Detailed information for compound 1627577

Basic information

Technical information
  • TDR Targets ID: 1627577
  • Name: (6E,8R,9S,13S,14S,17S)-6-hydroxyimino-13-meth yl-2-(2,2,2-trifluoroethoxy)-8,9,11,12,14,15, 16,17-octahydro-7H-cyclopenta[a]phenanthrene- 3,17-diol
  • MW: 399.404 | Formula: C20H24F3NO4
  • H donors: 3 H acceptors: 3 LogP: 4.15 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O/N=C/1\C[C@@H]2[C@@H](c3c1cc(O)c(c3)OCC(F)(F)F)CC[C@]1([C@H]2CC[C@@H]1O)C
  • InChi: 1S/C20H24F3NO4/c1-19-5-4-10-11-8-17(28-9-20(21,22)23)16(25)7-13(11)15(24-27)6-12(10)14(19)2-3-18(19)26/h7-8,10,12,14,18,25-27H,2-6,9H2,1H3/b24-15+/t10-,12-,14+,18+,19+/m1/s1
  • InChiKey: DNICCASOGBIQBS-WBNCGUHTSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (8R,9S,13S,14S,17S)-6-hydroxyimino-13-methyl-2-(2,2,2-trifluoroethoxy)-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthrene-3,17-diol
  • (8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-2-(2,2,2-trifluoroethoxy)-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one oxime
  • 2-Trifluoroethoxy-6-hydroxyiminoestra-1,3,5(10)-trien-3,17-.beta.-diol
  • NCI60_029176

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved protein 0.0038 0.0198 0.0685
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.1307 0.5327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0335 0.0873
Schistosoma mansoni hypothetical protein 0.0523 0.5481 0.7103
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0509
Toxoplasma gondii cathepsin CPC1 0.0363 0.3734 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0123 0.112 0.1447
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.1307 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0287 0.0283
Schistosoma mansoni sex comb on midleg homolog 0.0101 0.088 0.1136
Echinococcus multilocularis fibrillin 1 0.0042 0.0245 0.0241
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0198 0.0506
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Echinococcus granulosus lysine specific demethylase 5A 0.0123 0.112 0.1117
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0021 0.0009 0.0027
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0007
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Schistosoma mansoni jumonji domain containing protein 0.0119 0.108 0.1395
Echinococcus granulosus peroxisome assembly protein 26 0.0022 0.0019 0.0015
Onchocerca volvulus 0.0075 0.0603 0.1782
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0168 0.5019
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0063 0.047 0.121
Onchocerca volvulus 0.0101 0.088 0.2604
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0287 0.0283
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0075 0.0603 0.1573
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.011 0.0271
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0067 0.051 0.0506
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0021 0.0009 0.0275
Schistosoma mansoni bromodomain containing protein 0.0071 0.0558 0.0718
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0287 0.0367
Echinococcus multilocularis tubulin alpha 3 chain 0.0022 0.0019 0.0015
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0067 0.051 0.0506
Echinococcus granulosus transmembrane protease serine 3 0.0067 0.051 0.0506
Echinococcus granulosus Tubulin alpha 1 chain 0.0022 0.0019 0.0015
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0101 0.088 0.2604
Loa Loa (eye worm) hypothetical protein 0.0042 0.0243 0.0626
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0037 0.0062
Brugia malayi Bromodomain containing protein 0.0042 0.0242 0.0624
Echinococcus multilocularis Tubulin alpha 1 chain 0.0022 0.0019 0.0015
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.0021 0.0009 0.0005
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0671 0.0667
Schistosoma mansoni protein phosphatase 2C 0.0032 0.013 0.0163
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0034 0.004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0393 0.1006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0954 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0082 0.0194
Schistosoma mansoni jumonji/arid domain-containing protein 0.0123 0.112 0.1447
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Echinococcus multilocularis cubilin 0.0021 0.0009 0.0005
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0021 0.0009 0.0024
Brugia malayi MH1 domain containing protein 0.0026 0.0064 0.0165
Brugia malayi beta-lactamase family protein 0.0038 0.0198 0.0509
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0.0168 0.5019
Echinococcus granulosus Mastin 0.0067 0.051 0.0506
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0188 0.0481
Brugia malayi alpha-tubulin 0.0022 0.0019 0.005
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.013 0.0335
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Echinococcus granulosus tubulin subunit TubB 0.0022 0.0019 0.0015
Echinococcus granulosus microtubule associated protein 2 0.0729 0.7715 0.7714
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.112 0.2885
Plasmodium vivax endoplasmin, putative 0.0035 0.0168 0.04
Loa Loa (eye worm) hypothetical protein 0.0062 0.0465 0.1197
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0021 0.0009 0.0024
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.013 0.0126
Echinococcus granulosus tubulin alpha 1C chain 0.0022 0.0019 0.0015
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0021 0.0009 0.0024
Echinococcus multilocularis phd:f box containing protein 0.0032 0.013 0.0126
Toxoplasma gondii subtilisin SUB12 0.0075 0.0603 0.1573
Trypanosoma brucei alpha tubulin 0.0022 0.0019 0.0575
Schistosoma mansoni hypothetical protein 0.0401 0.4146 0.5371
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0147 0.0378
Schistosoma mansoni cpg binding protein 0.0032 0.0131 0.0165
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0113
Toxoplasma gondii microneme protein, putative 0.0075 0.0603 0.1573
Schistosoma mansoni glutaminase 0.028 0.2838 0.3675
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.1604 0.1601
Toxoplasma gondii calcium binding egf domain-containing protein 0.0042 0.0245 0.0608
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0147 0.0517
Onchocerca volvulus 0.0075 0.0603 0.1782
Loa Loa (eye worm) hypothetical protein 0.0032 0.013 0.0335
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0147 0.0378
Toxoplasma gondii ABC1 family protein 0.0038 0.0198 0.048
Leishmania major hypothetical protein, conserved 0.0038 0.0198 0.0587
Echinococcus multilocularis tubulin alpha 1C chain 0.0022 0.0019 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0188 0.0481
Echinococcus granulosus tubulin alpha chain 0.0022 0.0019 0.0015
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0671 0.0865
Echinococcus multilocularis microtubule associated protein 2 0.0729 0.7715 0.7714
Trichomonas vaginalis heat shock protein, putative 0.0028 0.009 0.0217
Brugia malayi Endoplasmin precursor 0.0035 0.0168 0.0432
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0818 0.8688 0.8688
Brugia malayi Trypsin-like protease protein 5 0.0067 0.051 0.1314
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Leishmania major hypothetical protein, conserved 0.0329 0.3367 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0022 0.0019 0.0015
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0147 0.0424
Echinococcus granulosus cubilin 0.0021 0.0009 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.018 0.0557
Brugia malayi tubulin alpha-2 chain 0.0022 0.0019 0.005
Brugia malayi glutaminase DH11.1 0.028 0.2838 0.7309
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0509
Loa Loa (eye worm) mbt repeat family protein 0.0101 0.088 0.2266
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0223 0.0661
Brugia malayi Nematode astacin protease protein 30 0.0021 0.0009 0.0024
Loa Loa (eye worm) Smad1 0.0026 0.0064 0.0165
Toxoplasma gondii heat shock protein HSP90 0.0035 0.0168 0.04
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0037 0.0096
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0198 0.0697
Mycobacterium ulcerans glutaminase 0.028 0.2838 1
Schistosoma mansoni pyruvate kinase 0.0033 0.0147 0.0185
Onchocerca volvulus 0.0038 0.0198 0.0576
Loa Loa (eye worm) DOMON domain-containing protein 0.0111 0.0989 0.2548
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0309 0.0796
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.1442 0.3715
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Schistosoma mansoni hypothetical protein 0.0048 0.0309 0.0396
Echinococcus granulosus polycomb protein SCMH1 0.0101 0.088 0.0876
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0363 0.3734 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0082 0.0194
Loa Loa (eye worm) alpha-tubulin 0.0022 0.0019 0.005
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0363 0.3734 1
Loa Loa (eye worm) PAN domain-containing protein 0.0075 0.0603 0.1554
Trichomonas vaginalis esterase, putative 0.0038 0.0198 0.0506
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0064 0.006
Onchocerca volvulus 0.0038 0.0198 0.0576
Loa Loa (eye worm) heat shock protein 90 0.0035 0.0168 0.0432
Echinococcus multilocularis cpg binding protein 0.0032 0.0131 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0254 0.0658
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0028 0.009 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Echinococcus multilocularis tubulin alpha chain 0.0022 0.0019 0.0015
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.002 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Giardia lamblia Pyruvate kinase 0.0033 0.0147 0.0343
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0147 0.0424
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Brugia malayi jmjC domain containing protein 0.0032 0.013 0.0335
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.04 0.4141 0.4139
Echinococcus granulosus Tubulin alpha 1 chain 0.0022 0.0019 0.0015
Echinococcus multilocularis CUB 0.0021 0.0009 0.0005
Schistosoma mansoni alpha-glucosidase 0.0144 0.1351 0.1747
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0363 0.3734 0.4838
Loa Loa (eye worm) hypothetical protein 0.0048 0.0309 0.0796
Echinococcus multilocularis zinc finger protein 0.0023 0.0036 0.0032
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0327 0.0841
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.013 0.0298
Entamoeba histolytica hypothetical protein 0.0023 0.0034 0.0051
Schistosoma mansoni hypothetical protein 0.0023 0.0031 0.0035
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0188 0.056
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0147 0.0343
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0062 0.0465 0.1197
Onchocerca volvulus 0.0329 0.3367 1
Echinococcus multilocularis heat shock protein 90 0.0028 0.009 0.0086
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.2901 0.7757
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0021 0.0009 0.0007
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0198 0.0685
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0034 0.004
Brugia malayi CUB domain containing protein 0.0021 0.0009 0.0024
Trichomonas vaginalis heat shock protein, putative 0.0022 0.002 0.0028
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Plasmodium vivax heat shock protein 86, putative 0.0035 0.0168 0.04
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0028 0.009 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0222 0.0571
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0147 0.0436
Onchocerca volvulus 0.0021 0.0009 0.0015
Echinococcus granulosus smad 0.0026 0.0064 0.006
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Echinococcus multilocularis Mastin 0.0067 0.051 0.0506
Echinococcus granulosus heat shock protein 90 0.0035 0.0168 0.0164
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0188 0.0481
Brugia malayi jmjC domain containing protein 0.0119 0.108 0.2781
Mycobacterium leprae Probable lipase LipE 0.0038 0.0198 0.1286
Loa Loa (eye worm) PAN domain-containing protein 0.0075 0.0603 0.1554
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0067 0.051 0.1314
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0335 1
Echinococcus granulosus Tolloid protein 1 0.0063 0.047 0.0466
Trypanosoma brucei alpha tubulin 0.0022 0.0019 0.0575
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0198 0.0506
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Echinococcus granulosus neuropeptide receptor A26 0.0938 1 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.1307 0.4605
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0034 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0154 0.0387
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.018 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0188 0.056
Echinococcus multilocularis Tubulin alpha 1 chain 0.0022 0.0019 0.0015
Brugia malayi Tubulin alpha-2 chain 0.0022 0.0019 0.005
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0198 0.0685
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Brugia malayi Trypsin family protein 0.0067 0.051 0.1314
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.4146 0.4143
Entamoeba histolytica hypothetical protein 0.0036 0.018 0.0557
Echinococcus granulosus alpha tubulin 0.0022 0.0019 0.0015
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.013 0.0386
Schistosoma mansoni hypothetical protein 0.0048 0.0309 0.0396
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0335 0.0873
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Brugia malayi MH2 domain containing protein 0.0376 0.3883 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0101 0.088 0.1136
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0063 0.047 0.121
Brugia malayi Kelch motif family protein 0.0021 0.0009 0.0024
Echinococcus granulosus dnaJ subfamily B 0.0401 0.4146 0.4143
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0168 0.5019
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.013 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Brugia malayi PHD-finger family protein 0.0029 0.01 0.0257
Onchocerca volvulus 0.0111 0.0989 0.293
Loa Loa (eye worm) hypothetical protein 0.0101 0.088 0.2266
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0509
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0198 0.0506
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0064 0.0078
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0309 0.0305
Loa Loa (eye worm) hypothetical protein 0.0041 0.0229 0.0589
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0021 0.0009 0.0024
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Schistosoma mansoni phd/f-box containing protein 0.0032 0.013 0.0163
Brugia malayi jmjC domain containing protein 0.0032 0.013 0.0335
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0113 0.0279
Brugia malayi jmjC domain containing protein 0.0032 0.013 0.0335
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0021 0.0009 0.0007
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0021 0.0009 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.011 0.0271
Loa Loa (eye worm) hypothetical protein 0.0032 0.013 0.0335
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.013 0.0163
Brugia malayi hypothetical protein 0.0067 0.051 0.1314
Loa Loa (eye worm) hypothetical protein 0.0048 0.0311 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0193
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0067 0.051 0.0657
Mycobacterium ulcerans heat shock protein 90 0.0028 0.009 0.0317
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0198 0.0509
Brugia malayi beta-lactamase family protein 0.0038 0.0198 0.0509
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0335 0.0994
Brugia malayi Cytochrome P450 family protein 0.005 0.0327 0.0841
Loa Loa (eye worm) CUB domain-containing protein 0.0021 0.0009 0.0024
Mycobacterium ulcerans lipase LipD 0.0038 0.0198 0.0697
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0198 0.0685
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Loa Loa (eye worm) hypothetical protein 0.0083 0.0689 0.1775
Echinococcus granulosus histone acetyltransferase MYST2 0.0115 0.1031 0.1028
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Echinococcus multilocularis histone acetyltransferase MYST2 0.0115 0.1031 0.1028
Brugia malayi mbt repeat family protein 0.0101 0.088 0.2266
Entamoeba histolytica hypothetical protein 0.0036 0.018 0.0557
Brugia malayi Kringle domain containing protein 0.0329 0.3367 0.8671
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.009 0.0267
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0222 0.0571
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0147 0.0378
Echinococcus multilocularis enteropeptidase 0.0067 0.051 0.0506
Schistosoma mansoni zinc finger protein 0.0023 0.0036 0.0041
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0147 0.0436
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0198 0.0509
Loa Loa (eye worm) alpha-tubulin 0.0022 0.0019 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0198 0.0251
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0034 0.0101
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.1604 0.4132
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0185 0.0476
Echinococcus granulosus Smad4 0.0026 0.0064 0.006
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.013 0.0335
Schistosoma mansoni Smad4 0.0026 0.0064 0.0078
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0188 0.0481
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Echinococcus multilocularis neuropeptide receptor A26 0.0938 1 1
Echinococcus multilocularis endoplasmin 0.0028 0.009 0.0086
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.0168 0.0516
Onchocerca volvulus 0.0127 0.1165 0.3453
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Brugia malayi tubulin alpha chain - mouse 0.0022 0.0019 0.005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0188 0.0481
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0067 0.051 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0113 0.0279
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0034 0.004
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0492 0.0633
Echinococcus multilocularis polycomb protein SCMH1 0.0101 0.088 0.0876
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0335 0.1094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0082 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0363 0.3734 1
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0147 0.0369
Toxoplasma gondii microneme protein MIC17A 0.0075 0.0603 0.1573
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0198 0.0194
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0515 0.0511
Onchocerca volvulus 0.0021 0.0009 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0198 0.0251
Brugia malayi Calcium binding EGF domain containing protein 0.0042 0.0245 0.0632
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0671 0.1729
Loa Loa (eye worm) tubulin alpha chain 0.0022 0.0019 0.005
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0091 0.0234
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0335 1
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0492 0.1267
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0147 0.4385
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0515 0.0511
Schistosoma mansoni hypothetical protein 0.0615 0.6483 0.8402
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Brugia malayi Trypsin family protein 0.0067 0.051 0.1314
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0335 0.0994
Brugia malayi hypothetical protein 0.0021 0.0009 0.0024
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.013 0.0163
Plasmodium falciparum endoplasmin, putative 0.0022 0.002 0.0001
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0363 0.3734 1
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Echinococcus granulosus laminin 0.0042 0.0245 0.0241
Leishmania major pyruvate kinase 0.0033 0.0147 0.0436
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0492 0.0633
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0509
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0168 0.0499
Echinococcus granulosus SAM and MBT domain containing protein 0.0101 0.088 0.0876
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.013 0.0126
Schistosoma mansoni hypothetical protein 0.0329 0.3367 0.4361
Schistosoma mansoni alpha-glucosidase 0.0144 0.1351 0.1747
Loa Loa (eye worm) PAN domain-containing protein 0.0075 0.0603 0.1554
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0287 0.0739
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.1604 0.1601
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0019 0.0027
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0067 0.051 0.0657
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0492 0.0633
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Loa Loa (eye worm) MBCTL1 0.0115 0.1031 0.2657
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0119 0.108 0.1076
Echinococcus granulosus geminin 0.0523 0.5481 0.5479
Echinococcus granulosus endonuclease exonuclease phosphatase 0.04 0.4141 0.4139
Brugia malayi Muscle positioning protein 4 0.0127 0.1165 0.3001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0193
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Onchocerca volvulus 0.0097 0.0837 0.2477
Echinococcus granulosus tubulin alpha chain 0.0022 0.0019 0.0015
Giardia lamblia Grp94/Hsp90 0.0028 0.009 0.019
Schistosoma mansoni hypothetical protein 0.0048 0.0309 0.0396
Loa Loa (eye worm) TK/ROR protein kinase 0.0329 0.3367 0.8671
Echinococcus multilocularis glycoprotein Antigen 5 0.0067 0.051 0.0506
Onchocerca volvulus 0.0067 0.051 0.1505
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Echinococcus granulosus pyruvate kinase 0.0033 0.0147 0.0143
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0309 0.0305
Brugia malayi Trypsin family protein 0.0067 0.051 0.1314
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0329 0.3367 0.9011
Loa Loa (eye worm) hypothetical protein 0.0104 0.0918 0.2364
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0198 0.0697
Onchocerca volvulus 0.0075 0.0603 0.1782
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0214 0.021
Loa Loa (eye worm) hypothetical protein 0.0127 0.1165 0.3001
Echinococcus multilocularis tubulin alpha chain 0.0022 0.0019 0.0015
Echinococcus granulosus tubulin alpha 1C chain 0.0022 0.0019 0.0015
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0.0168 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0335 0.0873
Onchocerca volvulus 0.0021 0.0009 0.0015
Schistosoma mansoni tubulin subunit alpha 0.0022 0.0019 0.002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0188 0.0481
Brugia malayi Bromodomain containing protein 0.0084 0.0698 0.1797
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.2901 1
Echinococcus multilocularis tissue type plasminogen activator 0.0329 0.3367 0.3364
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0671 0.0667
Onchocerca volvulus 0.0111 0.0989 0.293
Brugia malayi Protein kinase domain containing protein 0.0329 0.3367 0.8671
Echinococcus granulosus endoplasmin 0.0028 0.009 0.0086
Echinococcus multilocularis SAM and MBT domain containing protein 0.0101 0.088 0.0876
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Schistosoma mansoni tubulin subunit alpha 0.0022 0.0019 0.002
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0198 0.0194
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0188 0.0587
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0119 0.108 0.1076
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0287 0.0283
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Echinococcus granulosus GPCR family 2 0.0048 0.0309 0.0305
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0309 0.0796
Brugia malayi TAR-binding protein 0.0065 0.0492 0.1267
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.009 0.0086
Loa Loa (eye worm) hypothetical protein 0.0042 0.0245 0.0632
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0168 0.0499
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.2901 1
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0147 0.0378
Brugia malayi CUB domain containing protein 0.0021 0.0009 0.0024
Onchocerca volvulus 0.0038 0.0198 0.0576
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0019 0.0027
Onchocerca volvulus 0.0028 0.0091 0.0258
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0309 0.0796
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0062 0.0465 0.1197
Schistosoma mansoni hypothetical protein 0.0036 0.018 0.0228
Schistosoma mansoni hypothetical protein 0.0067 0.051 0.0657
Onchocerca volvulus 0.0075 0.0603 0.1782
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0222 0.0571
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0492 0.0633
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.0168 0.0499
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0067 0.051 0.0657
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0064 0.006
Loa Loa (eye worm) endoplasmin 0.0035 0.0168 0.0432
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0492 0.1267
Loa Loa (eye worm) beta-lactamase 0.0038 0.0198 0.0509
Echinococcus multilocularis heat shock protein 0.0035 0.0168 0.0164
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Trypanosoma brucei glucosidase, putative 0.0037 0.0188 0.5634
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.018 0.0176
Loa Loa (eye worm) hypothetical protein 0.0329 0.3367 0.8671
Schistosoma mansoni tubulin subunit alpha 0.0022 0.0019 0.002
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.0168 0.0516
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0007
Loa Loa (eye worm) PAN domain-containing protein 0.0075 0.0603 0.1554
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Trypanosoma cruzi heat shock protein 90, putative 0.0021 0.0011 0.0032
Echinococcus granulosus glycoprotein Antigen 5 0.0067 0.051 0.0506
Brugia malayi CXXC zinc finger family protein 0.0028 0.0091 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0082 0.0194
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0198 0.0587
Onchocerca volvulus 0.0075 0.0603 0.1782
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0509
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.009 0.0267
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0335 0.1094
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0188 0.0485
Schistosoma mansoni sex comb on midleg homolog 0.0101 0.088 0.1136
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0222 0.0571
Brugia malayi hypothetical protein 0.0036 0.018 0.0463
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Loa Loa (eye worm) RNA binding protein 0.0065 0.0492 0.1267
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0287 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0193
Trypanosoma brucei alpha tubulin 0.0022 0.0019 0.0575
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0188 0.0456
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Echinococcus multilocularis tubulin alpha chain 0.0022 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0042 0.0245 0.0632
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0198 0.0685
Mycobacterium ulcerans beta-lactamase 0.0038 0.0198 0.0697
Echinococcus granulosus cubilin 0.0021 0.0009 0.0005
Brugia malayi Tubulin alpha chain 0.0022 0.0019 0.005
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0198 0.0506
Schistosoma mansoni alpha tubulin 0.0022 0.0019 0.002
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0034 0.1017
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.018 0.0228
Schistosoma mansoni hypothetical protein 0.0111 0.0989 0.1278
Onchocerca volvulus 0.0111 0.0989 0.293
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0067 0.051 0.0657
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0188 0.0184
Echinococcus granulosus tubulin alpha 3 chain 0.0022 0.0019 0.0015
Echinococcus multilocularis tubulin alpha chain 0.0022 0.0019 0.0015
Onchocerca volvulus 0.0081 0.0671 0.1984
Schistosoma mansoni endoplasmin 0.0035 0.0168 0.0212
Mycobacterium tuberculosis Conserved protein 0.0038 0.0198 0.0685
Brugia malayi Nematode astacin protease protein 30 0.0021 0.0009 0.0024
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0034 0.004
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0071 0.0067
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0309 0.0305
Schistosoma mansoni heat shock protein 0.0035 0.0168 0.0212
Toxoplasma gondii PAN domain-containing protein 0.0075 0.0603 0.1573
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.013 0.3888
Echinococcus granulosus tubulin alpha 3 chain 0.0022 0.0019 0.0015
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0363 0.3734 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.013 0.0386
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0188 0.0481
Toxoplasma gondii heat shock protein 90, putative 0.0035 0.0168 0.04
Toxoplasma gondii PAN domain-containing protein 0.0075 0.0603 0.1573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0198 0.0685
Echinococcus multilocularis geminin 0.0523 0.5481 0.5479
Schistosoma mansoni smad1 5 8 and 0.0026 0.0064 0.0078
Onchocerca volvulus 0.0021 0.0009 0.0015
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0028 0.009 0.0267
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0067 0.051 0.0506
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0019 0.0027
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0198 0.0685
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0287 0.0739
Brugia malayi beta-lactamase 0.0038 0.0198 0.0509
Plasmodium falciparum heat shock protein 90 0.0035 0.0168 0.04
Schistosoma mansoni pyruvate kinase 0.0033 0.0147 0.0185
Echinococcus granulosus heat shock protein 90 0.0028 0.009 0.0086
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Toxoplasma gondii microneme protein MIC4 0.0075 0.0603 0.1573
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0335 0.0862
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0024
Brugia malayi RNA binding protein 0.0065 0.0492 0.1267
Echinococcus multilocularis tubulin alpha 3 chain 0.0022 0.0019 0.0015
Loa Loa (eye worm) transcription factor SMAD2 0.0376 0.3883 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0071 0.0067
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0028 0.009 0.0439
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.013 0.0126
Onchocerca volvulus 0.0067 0.051 0.1505
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0064 0.0165
Schistosoma mansoni hypothetical protein 0.0104 0.0918 0.1185
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0168 0.0499
Echinococcus multilocularis Smad4 0.0026 0.0064 0.006
Onchocerca volvulus 0.0075 0.0603 0.1782
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Toxoplasma gondii microneme protein MIC17B 0.0075 0.0603 0.1573
Echinococcus multilocularis cubilin 0.0021 0.0009 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0198 0.0506
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0063 0.047 0.0604
Trypanosoma brucei alpha tubulin 0.0022 0.0019 0.0575
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0198 0.0685
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0042 0.0245 0.0632
Trypanosoma cruzi hypothetical protein, conserved 0.0329 0.3367 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Brugia malayi jmjC domain containing protein 0.0032 0.013 0.0335
Loa Loa (eye worm) hypothetical protein 0.0045 0.0271 0.0699
Schistosoma mansoni smad1 5 8 and 0.0026 0.0064 0.0078
Echinococcus multilocularis tubulin alpha 1C chain 0.0022 0.0019 0.0015
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Trichomonas vaginalis tubulin epsilon chain, putative 0.0022 0.0019 0.0027
Brugia malayi jmjC domain containing protein 0.0123 0.112 0.2885
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0492 0.0633
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0147 0.0369
Toxoplasma gondii PAN domain-containing protein 0.0075 0.0603 0.1573
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.002 0.0004 0.0011
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0019 0.0027
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0335 0.0331
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0492 0.0488
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0363 0.3734 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Brugia malayi CUB domain containing protein 0.0021 0.0009 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.1604 0.4132
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Toxoplasma gondii PAN/Apple domain-containing protein 0.0075 0.0603 0.1573
Trichomonas vaginalis heat shock protein, putative 0.0028 0.009 0.0217
Echinococcus multilocularis heat shock protein 90 0.0035 0.0168 0.0164
Echinococcus multilocularis laminin 0.0042 0.0245 0.0241
Echinococcus granulosus heat shock protein 0.0035 0.0168 0.0164
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.2901 1
Toxoplasma gondii hypothetical protein 0.0075 0.0603 0.1573
Schistosoma mansoni jumonji domain containing protein 0.0032 0.013 0.0163
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0335 0.0429
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Trichomonas vaginalis glutaminase, putative 0.028 0.2838 0.7594
Brugia malayi Tubulin alpha-2 chain 0.0022 0.0019 0.005
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0188 0.0184
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0509
Echinococcus multilocularis peroxisome assembly protein 26 0.0022 0.0019 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.1442 0.3715
Loa Loa (eye worm) trypsin family protein 0.0067 0.051 0.1314
Giardia lamblia GTOR 0.0051 0.0335 0.0849
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0434 0.0558
Schistosoma mansoni alpha tubulin 0.0022 0.0019 0.002
Brugia malayi MH2 domain containing protein 0.0026 0.0064 0.0165
Toxoplasma gondii microneme protein MIC17C 0.0075 0.0603 0.1573
Schistosoma mansoni endoplasmin 0.0035 0.0168 0.0212
Loa Loa (eye worm) hypothetical protein 0.0152 0.1442 0.3715
Schistosoma mansoni hypothetical protein 0.0048 0.0309 0.0396
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0147 0.4385
Echinococcus granulosus zinc finger protein 0.0023 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.005
Echinococcus granulosus Tubulin alpha 1 chain 0.0022 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Mycobacterium ulcerans hypothetical protein 0.0067 0.051 0.1798
Loa Loa (eye worm) hypothetical protein 0.0115 0.1031 0.2657
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.013 0.0126
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.013 0.0298
Schistosoma mansoni alpha glucosidase 0.0037 0.0188 0.0239
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0198 0.591
Schistosoma mansoni microtubule-associated protein tau 0.0729 0.7715 1
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0019 0.0027
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.013 0.0298
Brugia malayi CUB domain containing protein 0.0041 0.0229 0.0589
Onchocerca volvulus 0.0075 0.0603 0.1782
Echinococcus multilocularis GPCR, family 2 0.0048 0.0309 0.0305
Brugia malayi MH1 domain containing protein 0.0026 0.0064 0.0165
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0045 0.1337
Trichomonas vaginalis tubulin epsilon chain, putative 0.0022 0.0019 0.0027
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.013 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Loa Loa (eye worm) glutaminase 2 0.028 0.2838 0.7309
Loa Loa (eye worm) tubulin alpha chain 0.0022 0.0019 0.005
Onchocerca volvulus 0.0067 0.051 0.1505
Brugia malayi mbt repeat family protein 0.0101 0.088 0.2266
Schistosoma mansoni smad 0.0026 0.0064 0.0078
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0019 0.0027
Loa Loa (eye worm) DPY-31 protein 0.0021 0.0009 0.0024
Onchocerca volvulus 0.0111 0.0989 0.293
Schistosoma mansoni egf-like domain protein 0.0042 0.0245 0.0313
Chlamydia trachomatis pyruvate kinase 0.0033 0.0147 1
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0031 0.008
Onchocerca volvulus 0.0075 0.0603 0.1782
Brugia malayi heat shock protein 90 0.0035 0.0168 0.0432
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.013 0.0335
Toxoplasma gondii hypothetical protein 0.0075 0.0603 0.1573
Loa Loa (eye worm) tubulin alpha-2 chain 0.0022 0.0019 0.005
Echinococcus granulosus tubulin alpha chain 0.0022 0.0019 0.0015
Plasmodium falciparum pyruvate kinase 0.0033 0.0147 0.0343
Trichomonas vaginalis heat shock protein, putative 0.0028 0.009 0.0217
Echinococcus granulosus tubulin alpha chain 0.0022 0.0019 0.0015
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0022 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.2424 1
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0113 0.0279
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.017 0.0166
Echinococcus multilocularis pyruvate kinase 0.0033 0.0147 0.0143
Treponema pallidum heat shock protein 90 0.0028 0.009 0.0195
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.017 0.0166
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0115 0.1031 0.1028
Echinococcus granulosus phd:f box containing protein 0.0032 0.013 0.0126
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0064 0.006
Onchocerca volvulus Putative cubilin 0.0037 0.0185 0.0538
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0115 0.1031 0.1028
Schistosoma mansoni hypothetical protein 0.0067 0.051 0.0657
Mycobacterium tuberculosis Conserved protein 0.0038 0.0198 0.0685
Toxoplasma gondii calcium binding egf domain-containing protein 0.0042 0.0245 0.0608
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0067 0.051 0.0657
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0287 0.0367
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0335 0.0994
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0335 0.0862
Toxoplasma gondii kringle domain-containing protein 0.0329 0.3367 0.9011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Loa Loa (eye worm) glutaminase 0.028 0.2838 0.7309
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0034 0.012
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0335 0.0994
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0007
Echinococcus multilocularis neuropeptide s receptor 0.0938 1 1
Echinococcus granulosus enteropeptidase 0.0067 0.051 0.0506
Plasmodium falciparum cysteine repeat modular protein 1 0.0329 0.3367 0.9011
Schistosoma mansoni smad1 5 8 and 0.0026 0.0064 0.0078
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0147 0.0885
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0021 0.0009 0.0024
Toxoplasma gondii PAN domain-containing protein 0.0075 0.0603 0.1573
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0147 0.0472
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0013 0.0391
Schistosoma mansoni hypothetical protein 0.0523 0.5481 0.7103
Entamoeba histolytica hypothetical protein 0.0036 0.018 0.0557
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0223 0.0661
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.1604 0.1601
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0115 0.1031 0.2657
Echinococcus multilocularis transmembrane protease serine 3 0.0067 0.051 0.0506
Schistosoma mansoni alpha tubulin 0.0022 0.0019 0.002
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0194 0.0469
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.002 0.0004 0.0011
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0188 0.056
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0223 0.6651
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.2901 0.7763
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Toxoplasma gondii PAN domain-containing protein 0.0075 0.0603 0.1573
Loa Loa (eye worm) hypothetical protein 0.0081 0.0671 0.1729
Schistosoma mansoni cpg binding protein 0.0032 0.0131 0.0165
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0188 0.0587
Onchocerca volvulus 0.0067 0.051 0.1505
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0735 0.0948
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0096
Brugia malayi Lectin C-type domain containing protein 0.0021 0.0009 0.0024
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0188 0.0481
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0067 0.051 0.0506
Giardia lamblia Heat shock protein HSP 90-alpha 0.0028 0.009 0.019
Echinococcus multilocularis smad 0.0026 0.0064 0.006
Brugia malayi CUB domain containing protein 0.0021 0.0009 0.0024
Brugia malayi SEA domain containing protein 0.0111 0.0989 0.2548
Onchocerca volvulus Arrow homolog 0.0062 0.0465 0.1369
Loa Loa (eye worm) hypothetical protein 0.0078 0.0629 0.1621
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0142 0.0356
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Echinococcus multilocularis Tolloid protein 1 0.0063 0.047 0.0466
Loa Loa (eye worm) CUB domain-containing protein 0.0021 0.0009 0.0024
Echinococcus granulosus pyruvate kinase 0.0033 0.0147 0.0143
Echinococcus multilocularis tubulin subunit TubB 0.0022 0.0019 0.0015
Onchocerca volvulus 0.0075 0.0603 0.1782
Brugia malayi Smad1 0.0026 0.0064 0.0165
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0064 0.0165
Echinococcus multilocularis pyruvate kinase 0.0033 0.0147 0.0143
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0147 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Brugia malayi Fibulin-1 precursor 0.0042 0.0245 0.0632
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0918 0.2364
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0309 0.0305
Echinococcus granulosus neuropilin nrp and tolloid tll 0.0021 0.0009 0.0005
Echinococcus granulosus tissue type plasminogen activator 0.0329 0.3367 0.3364
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Leishmania major hypothetical protein, conserved 0.0032 0.013 0.0386
Echinococcus multilocularis lysine specific demethylase 5A 0.0119 0.108 0.1076
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0198 0.0587
Schistosoma mansoni heat shock protein 0.0035 0.0168 0.0212
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0335 0.0331
Echinococcus multilocularis tubulin alpha chain 0.0022 0.0019 0.0015
Toxoplasma gondii PAN domain-containing protein 0.0075 0.0603 0.1573
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0287 0.0367
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0147 0.0424
Loa Loa (eye worm) hypothetical protein 0.0032 0.013 0.0335
Plasmodium vivax JmjC domain containing protein 0.0032 0.013 0.0298
Loa Loa (eye worm) PAN domain-containing protein 0.0075 0.0603 0.1554
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0021 0.0009 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0188 0.0485
Brugia malayi MH2 domain containing protein 0.0026 0.0064 0.0165
Echinococcus granulosus CUB 0.0021 0.0009 0.0005
Brugia malayi astacin protease protein 30 0.0021 0.0009 0.0024
Trypanosoma brucei heat shock protein, putative 0.0035 0.0168 0.5019
Onchocerca volvulus 0.0067 0.051 0.1505
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Loa Loa (eye worm) hypothetical protein 0.0033 0.0147 0.0378
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0.0168 0.0499
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.1442 0.3715
Onchocerca volvulus 0.0075 0.0603 0.1782
Echinococcus granulosus tar DNA binding protein 0.0065 0.0492 0.0488
Echinococcus multilocularis pyruvate kinase 0.0026 0.007 0.0066
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0214 0.021
Onchocerca volvulus 0.0067 0.051 0.1505
Echinococcus granulosus tubulin alpha chain 0.0022 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0492 0.1267
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0007
Schistosoma mansoni myelin transcription factor 1 myt1 0.0115 0.1031 0.1332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0194 0.0495
Loa Loa (eye worm) hypothetical protein 0.0075 0.0603 0.1554
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Toxoplasma gondii preprocathepsin c precursor, putative 0.0363 0.3734 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.051 0.1314
Trichomonas vaginalis heat shock protein, putative 0.0035 0.0168 0.0426
Brugia malayi PAN domain containing protein 0.0075 0.0603 0.1554
Loa Loa (eye worm) hypothetical protein 0.0111 0.0989 0.2548
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0147 0.0378
Schistosoma mansoni cercarial elastase (S01 family) 0.0067 0.051 0.0657
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Echinococcus granulosus cpg binding protein 0.0032 0.0131 0.0127
Brugia malayi basement membrane proteoglycan precursor 0.002 0.0004 0.0011
Brugia malayi enteropeptidase precursor 0.002 0.0004 0.0011
Trypanosoma cruzi alpha tubulin, putative 0.0022 0.0019 0.0057
Mycobacterium ulcerans hypothetical protein 0.0038 0.0198 0.0697
Trichomonas vaginalis endoplasmin, putative 0.0022 0.002 0.0028
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0188 0.0481
Echinococcus multilocularis hypothetical protein 0.0022 0.0019 0.0015
Onchocerca volvulus 0.0075 0.0603 0.1782
Brugia malayi Trypsin family protein 0.0067 0.051 0.1314
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0071 0.0087
Leishmania major alpha tubulin 0.0022 0.0019 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0222 0.0571
Leishmania major heat shock protein 83-1 0.0035 0.0168 0.0499
Leishmania major pyruvate kinase 0.0033 0.0147 0.0436
Loa Loa (eye worm) MH2 domain-containing protein 0.0376 0.3883 1
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0198 0.048
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0198 0.1286
Loa Loa (eye worm) hypothetical protein 0.0037 0.0185 0.0476

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -7.957 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.754 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.725 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.635 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.524 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.458 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.448 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.414 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.403 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.059 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.481 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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