Detailed information for compound 1663304

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2691.02 | Formula: C115H192N42O33
  • H donors: 42 H acceptors: 33 LogP: -17.24 Rotable bonds: 121
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)CC(C)C)Cc1ccccc1)CCC(=O)O)[C@H](O)C)CCC(=O)O)CCC(=O)O)CC(=O)O)CC(C)C)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCC(=O)N)CCCNC(=N)N)CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(cc1)O)N)CCCNC(=N)N)CCCCN
  • InChi: 1S/C115H192N42O33/c1-59(2)52-78(104(184)154-80(56-89(169)170)106(186)151-76(37-41-87(165)166)102(182)150-77(38-42-88(167)168)103(183)156-90(61(5)158)107(187)139-58-85(162)141-74(36-40-86(163)164)100(180)153-79(55-62-20-7-6-8-21-62)105(185)155-81(53-60(3)4)108(188)157-51-19-30-82(157)109(189)190)152-99(179)73(29-18-50-137-115(130)131)147-96(176)70(26-15-47-134-112(124)125)145-97(177)71(27-16-48-135-113(126)127)148-101(181)75(35-39-83(119)160)149-98(178)72(28-17-49-136-114(128)129)146-95(175)69(25-14-46-133-111(122)123)144-94(174)68(23-10-12-44-117)143-93(173)67(22-9-11-43-116)142-92(172)66(24-13-45-132-110(120)121)140-84(161)57-138-91(171)65(118)54-63-31-33-64(159)34-32-63/h6-8,20-21,31-34,59-61,65-82,90,158-159H,9-19,22-30,35-58,116-118H2,1-5H3,(H2,119,160)(H,138,171)(H,139,187)(H,140,161)(H,141,162)(H,142,172)(H,143,173)(H,144,174)(H,145,177)(H,146,175)(H,147,176)(H,148,181)(H,149,178)(H,150,182)(H,151,186)(H,152,179)(H,153,180)(H,154,184)(H,155,185)(H,156,183)(H,163,164)(H,165,166)(H,167,168)(H,169,170)(H,189,190)(H4,120,121,132)(H4,122,123,133)(H4,124,125,134)(H4,126,127,135)(H4,128,129,136)(H4,130,131,137)/t61-,65+,66+,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,79+,80+,81+,82+,90+/m1/s1
  • InChiKey: NJSMWXSKGFJOKZ-SPDKSDCBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0204 0.0198
Loa Loa (eye worm) CXXC zinc finger family protein 0.0119 0.0618 0.0612
Trichomonas vaginalis ran, putative 0.0022 0.0043 0.0148
Plasmodium vivax vivapain-3 0.0029 0.0087 0.1012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0108 0.0554 0.1914
Loa Loa (eye worm) hypothetical protein 0.008 0.0386 0.038
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0043 0.027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Leishmania major cathepsin L-like protease 0.0057 0.0249 0.1208
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0072 0.0819
Mycobacterium tuberculosis Probable reductase 0.0105 0.0534 0.1801
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0108 0.0554 0.0549
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0135 0.0634
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Loa Loa (eye worm) hypothetical protein 0.0108 0.0554 0.0549
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0044 0.0038
Onchocerca volvulus 0.0057 0.0249 0.0757
Plasmodium vivax vivapain-2 0.0057 0.0249 0.3108
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0147 0.0784 0.0778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0029 0.0087 0.0393
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0503 0.2897 0.9898
Echinococcus granulosus ornithine aminotransferase 0.0072 0.0339 0.0333
Schistosoma mansoni smad1 5 8 and 0.0017 0.0015 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0249 0.0861
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0072 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0784 0.2705
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0147 0.0784 0.0778
Echinococcus granulosus cathepsin l cysteine peptidase 0.0057 0.0249 0.0244
Toxoplasma gondii hypothetical protein 0.0057 0.0251 0.1907
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0279 0.1571 0.1565
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0147 0.0784 0.0778
Leishmania major glycerol uptake protein, putative 0.0147 0.0784 0.3888
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.005 0.0208 0.1
Mycobacterium ulcerans beta-lactamase 0.008 0.0386 0.1306
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0044 0.0038
Brugia malayi Cathepsin L-like precursor 0.0057 0.0249 0.0244
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0548 0.0542
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0044 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0044 0.0038
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0087 0.0595
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0249 0.2788
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0147 0.0784 0.0778
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0074 0.0255
Trypanosoma brucei glycerol uptake protein, putative 0.0147 0.0784 0.3888
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0286 0.0281
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0044 0.0038
Echinococcus granulosus cpg binding protein 0.0125 0.0658 0.0652
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0138 0.128
Plasmodium falciparum cysteine proteinase falcipain 3 0.0057 0.0249 0.3108
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0386 0.1332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0352 0.2002 1
Brugia malayi beta-lactamase family protein 0.008 0.0386 0.038
Echinococcus multilocularis neuropeptide receptor A26 0.0455 0.2609 0.2604
Echinococcus multilocularis muscleblind protein 0.1262 0.7392 0.739
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0249 0.0861
Brugia malayi MH1 domain containing protein 0.0017 0.0015 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0139 0.1303
Loa Loa (eye worm) MBOAT family protein 0.0147 0.0784 0.0778
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0043 0.0444
Brugia malayi MH2 domain containing protein 0.0017 0.0015 0.0009
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0135 0.0466
Mycobacterium leprae Probable lipase LipE 0.008 0.0386 0.1129
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0057 0.0249 0.0244
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0279 0.1571 0.1565
Brugia malayi Cytochrome P450 family protein 0.0051 0.0216 0.021
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0072 0.0339 0.0961
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0279 0.1571 0.1565
Echinococcus granulosus sterol O acyltransferase 1 0.0147 0.0784 0.0778
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0046 0.004
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0046 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.016 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0074 0.0255
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0072 0.0339 0.0961
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0066 0.0198
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0151 0.0714
Loa Loa (eye worm) hypothetical protein 0.008 0.0386 0.038
Trypanosoma brucei trypanothione reductase 0.0046 0.0186 0.089
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Echinococcus multilocularis neuropeptide s receptor 0.0455 0.2609 0.2604
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Echinococcus granulosus o acyltransferase membrane bound domain 0.0147 0.0784 0.0778
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0135 0.0129
Brugia malayi hypothetical protein 0.0273 0.1534 0.1528
Plasmodium vivax hypothetical protein, conserved 0.008 0.0386 0.4869
Loa Loa (eye worm) hypothetical protein 0.0147 0.0784 0.0778
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0108 0.0554 0.1914
Trypanosoma cruzi cruzipain precursor, putative 0.0019 0.0025 0.0083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0108 0.0554 0.0549
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0151 0.0714
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0044 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0279 0.1571 0.1565
Entamoeba histolytica cysteine proteinase 1, putative 0.0029 0.0087 0.0595
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0046 0.0131
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0138 0.0648
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0044 0.0038
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0038 0.0138 0.0648
Plasmodium vivax unspecified product 0.0019 0.0025 0.0214
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0422 0.2416 0.2411
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0044 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0043 0.063
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0534 0.1801
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0145 0.0139
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0151 0.0145
Schistosoma mansoni cpg binding protein 0.0125 0.0658 0.0652
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0044 0.0038
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0072 0.0339 0.1142
Schistosoma mansoni rab6-interacting 0.0039 0.0148 0.0142
Schistosoma mansoni smad1 5 8 and 0.0017 0.0015 0.0009
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Plasmodium vivax SET domain protein, putative 0.0063 0.0286 0.3584
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0749 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.0554 0.1914
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0044 0.0038
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0603 0.2037
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0139 0.0133
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0147 0.0784 0.6093
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0455 0.0449
Echinococcus granulosus smad 0.0017 0.0015 0.0009
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0015 0.0009
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0151 0.0493
Schistosoma mansoni hypothetical protein 0.0376 0.2144 0.2139
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0603 0.2037
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0148 0.0142
Leishmania major hypothetical protein, conserved 0.008 0.0386 0.1893
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0249 0.0244
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0072 0.0819
Brugia malayi Cathepsin L-like precursor 0.0057 0.0249 0.0244
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0135 0.0634
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0143 0.0494
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Brugia malayi Thioredoxin reductase 0.0046 0.0186 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0089 0.0633
Echinococcus multilocularis ornithine aminotransferase 0.0072 0.0339 0.0333
Loa Loa (eye worm) hypothetical protein 0.0049 0.0204 0.0198
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0534 0.1801
Schistosoma mansoni hypothetical protein 0.0315 0.1778 0.1773
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0386 0.1893
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0074 0.0255
Loa Loa (eye worm) hypothetical protein 0.0029 0.0089 0.0083
Echinococcus granulosus cathepsin l1 0.0057 0.0249 0.0244
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0147 0.0784 0.0778
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0148 0.0142
Onchocerca volvulus 0.008 0.0386 0.126
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0186 0.018
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.1702 1 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0089 0.0404
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0603 0.2037
Echinococcus multilocularis RUN 0.0039 0.0148 0.0142
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.016 0.119
Mycobacterium tuberculosis Conserved protein 0.008 0.0386 0.1293
Brugia malayi ecdysteroid receptor 0.0022 0.0044 0.0038
Plasmodium falciparum importin beta, putative 0.0029 0.0089 0.1038
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0112 0.0106
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0186 0.018
Schistosoma mansoni rotamase 0.0039 0.0143 0.0137
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0286 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0044 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0135 0.0634
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0066 0.0746
Onchocerca volvulus 0.0147 0.0784 0.2725
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0087 0.0081
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0072 0.0339 0.1131
Echinococcus granulosus importin subunit beta 1 0.0029 0.0089 0.0083
Trichomonas vaginalis transmembrane protein nessy, putative 0.0147 0.0784 0.2705
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0044 0.0038
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0087 0.0081
Brugia malayi Cytochrome P450 family protein 0.0022 0.0046 0.004
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0066 0.1751
Trichomonas vaginalis helicase, putative 0.0027 0.0074 0.0255
Onchocerca volvulus 0.0091 0.0455 0.1513
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0386 0.1893
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0072 0.0339 0.0961
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0135 0.0634
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0038 0.0138 0.0648
Trypanosoma cruzi cysteine proteinase, putative 0.0029 0.0087 0.0393
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0087 0.0595
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0009 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0147 0.0784 0.0778
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0066 0.02
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0087 0.0081
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0066 0.0454
Onchocerca volvulus 0.0119 0.0618 0.2114
Echinococcus granulosus dnaJ subfamily B 0.0904 0.5269 0.5267
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0046 0.019
Mycobacterium ulcerans acetylornithine aminotransferase 0.0072 0.0339 0.1142
Toxoplasma gondii histone lysine methyltransferase SET1 0.0231 0.128 1
Echinococcus multilocularis geminin 0.0376 0.2144 0.2139
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0074 0.0255
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0066 0.0746
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0057 0.0249 0.3108
Schistosoma mansoni microtubule-associated protein tau 0.1532 0.8994 0.8994
Leishmania major cathepsin L-like protease 0.0215 0.1191 0.5929
Schistosoma mansoni ran 0.0022 0.0043 0.0037
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0044 0.0038
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0072 0.0319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0279 0.1571 0.1565
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0028 0.0022
Schistosoma mansoni cpg binding protein 0.0119 0.0618 0.0612
Loa Loa (eye worm) hypothetical protein 0.0273 0.1534 0.1528
Brugia malayi Doublecortin family protein 0.0039 0.0148 0.0142
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0386 0.1332
Onchocerca volvulus 0.0057 0.0249 0.0757
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0139 0.1688
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0072 0.0499
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0548 0.0542
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0148 0.0142
Brugia malayi Cytochrome P450 family protein 0.0022 0.0046 0.004
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0043 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0044 0.0038
Echinococcus multilocularis ornithine aminotransferase 0.0072 0.0339 0.0333
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0044 0.0038
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0455 0.0449
Onchocerca volvulus 0.0057 0.0249 0.0757
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0142 0.0136
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0003
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0249 0.1208
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.008 0.0386 0.038
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0145 0.0139
Schistosoma mansoni hypothetical protein 0.0107 0.0548 0.0542
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.1384 0.1379
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0044 0.0038
Schistosoma mansoni hypothetical protein 0.0147 0.0784 0.0778
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0009 0.0003
Loa Loa (eye worm) beta-lactamase 0.008 0.0386 0.038
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0044 0.0038
Onchocerca volvulus 0.0057 0.0249 0.0757
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.008 0.0386 0.1306
Trichomonas vaginalis set domain proteins, putative 0.048 0.2759 0.9523
Onchocerca volvulus 0.0057 0.0249 0.0757
Mycobacterium tuberculosis Conserved protein 0.008 0.0386 0.1293
Mycobacterium tuberculosis Probable aminotransferase 0.0503 0.2897 0.9898
Leishmania major cathepsin L-like protease 0.0215 0.1191 0.5929
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0044 0.0038
Schistosoma mansoni smad 0.0017 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0139 0.0133
Schistosoma mansoni rab6-interacting 0.0039 0.0148 0.0142
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0142
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0043 0.0037
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.016 0.0552
Entamoeba histolytica hypothetical protein 0.0107 0.0548 0.6815
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0044 0.0038
Entamoeba histolytica hypothetical protein 0.0107 0.0548 0.6815
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0044 0.0038
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1012 0.5914 0.5911
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0039 0.0143 0.0137
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Echinococcus granulosus Aminotransferase class III 0.0072 0.0339 0.0333
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0025 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0167 0.0903 0.4484
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0066
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0108 0.0554 0.0549
Echinococcus granulosus cysteine protease 0.0029 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.1262 0.7392 0.739
Leishmania major cathepsin L-like protease 0.0057 0.0249 0.1208
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0066 0.0454
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0534 0.1801
Onchocerca volvulus Cathepsin F homolog 0.0057 0.0249 0.0757
Onchocerca volvulus 0.0057 0.0249 0.0757
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.016 0.119
Leishmania major cytochrome p450-like protein 0.0022 0.0046 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0167 0.0903 0.4484
Toxoplasma gondii peptidylprolyl isomerase 0.0038 0.0138 0.1016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0286 0.0281
Echinococcus granulosus cathepsin L cysteine protease 0.0029 0.0087 0.0081
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0148 0.0142
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0102 0.0096
Trypanosoma cruzi GUP1, putative 0.0147 0.0784 0.3888
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0135 0.0129
Toxoplasma gondii exonuclease III APE 0.0037 0.0135 0.0993
Brugia malayi steroid hormone receptor 0.0022 0.0044 0.0038
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0249 0.2788
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0148 0.0142
Echinococcus granulosus Smad4 0.0017 0.0015 0.0009
Echinococcus granulosus geminin 0.0376 0.2144 0.2139
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0148 0.0142
Trichomonas vaginalis rotamase, putative 0.0039 0.0143 0.0494
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0046 0.019
Loa Loa (eye worm) ctsf protein 0.0057 0.0249 0.0244
Brugia malayi Cathepsin L-like precursor 0.0038 0.0139 0.0133
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0249 0.0757
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0197 0.108 0.5374
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0029 0.0087 0.0393
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0508 0.2927 1
Brugia malayi Muscleblind-like protein 0.1262 0.7392 0.739
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0072 0.0339 0.1131
Brugia malayi nuclear receptor NHR-88 0.0022 0.0044 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1646 0.9665 0.9665
Echinococcus granulosus expressed protein 0.0039 0.0143 0.0137
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0147 0.0784 0.0778
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Echinococcus granulosus neuropeptide s receptor 0.0455 0.2609 0.2604
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0272 0.1322
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0135 0.0433
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0044 0.0038
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0087 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0749 0.0743
Echinococcus multilocularis Aminotransferase class III 0.0072 0.0339 0.0333
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0029 0.0087 0.0393
Loa Loa (eye worm) hypothetical protein 0.0057 0.0249 0.0244
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0044 0.0038
Leishmania major cathepsin L-like protease 0.0057 0.0249 0.1208
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0249 0.0244
Trypanosoma cruzi cruzipain precursor, putative 0.0215 0.1191 0.5929
Brugia malayi Importin beta-1 subunit 0.0029 0.0089 0.0083
Trypanosoma cruzi cysteine protease, putative 0.0029 0.0087 0.0393
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0135 0.0129
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0151 0.1119
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0066 0.0746
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0148 0.0142
Loa Loa (eye worm) hypothetical protein 0.008 0.0386 0.038
Echinococcus granulosus microtubule associated protein 2 0.1532 0.8994 0.8994
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0044 0.0038
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Echinococcus multilocularis cysteine protease 0.0057 0.0249 0.0244
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0126 0.0403
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Brugia malayi Inositol-1 0.004 0.0151 0.0145
Trypanosoma brucei glycerol uptake protein, putative 0.0147 0.0784 0.3888
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0148 0.1796
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0147 0.0784 0.0778
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0108 0.0554 0.6906
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0204 0.0198
Echinococcus multilocularis muscleblind protein 1 0.1262 0.7392 0.739
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0087 0.0081
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0015 0.0009
Trypanosoma cruzi glycerol uptake protein, putative 0.0147 0.0784 0.3888
Loa Loa (eye worm) MBOAT family protein 0.0147 0.0784 0.0778
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0074 0.0255
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0025 0.0083
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0151 0.0521
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0056 0.0238
Echinococcus multilocularis zinc finger protein 0.1555 0.9131 0.913
Plasmodium falciparum cysteine proteinase falcipain 1 0.0029 0.0087 0.1012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0108 0.0554 0.2738
Mycobacterium tuberculosis Probable lipase LipE 0.008 0.0386 0.1293
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0108 0.0554 0.0549
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0019
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0108 0.0554 0.0549
Treponema pallidum alginate O-acetylation protein (algI) 0.0147 0.0784 1
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Brugia malayi hypothetical protein 0.0107 0.0548 0.0542
Echinococcus multilocularis sterol O acyltransferase 1 0.0147 0.0784 0.0778
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0056 0.0194
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0135 0.163
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0044 0.0038
Echinococcus granulosus RUN 0.0039 0.0148 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0046 0.004
Onchocerca volvulus 0.048 0.2759 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Echinococcus multilocularis snurportin 1 0.0315 0.1778 0.1773
Toxoplasma gondii cathepsin CPL 0.0057 0.0249 0.1894
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0249 0.0244
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0138 0.0648
Mycobacterium ulcerans hypothetical protein 0.0186 0.1014 0.3481
Loa Loa (eye worm) hypothetical protein 0.008 0.0386 0.038
Trypanosoma cruzi glycerol uptake protein, putative 0.0147 0.0784 0.3888
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Mycobacterium ulcerans hypothetical protein 0.0503 0.2897 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0044 0.0038
Onchocerca volvulus 0.008 0.0386 0.126
Schistosoma mansoni cathepsin F (C01 family) 0.0038 0.0139 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0044 0.0038
Echinococcus granulosus survival motor neuron protein 1 0.0273 0.1534 0.1528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0279 0.1571 0.1565
Loa Loa (eye worm) hypothetical protein 0.0038 0.0139 0.0133
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0044 0.0038
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0044 0.0038
Echinococcus granulosus cathepsin L cysteine proteinase 0.0057 0.0249 0.0244
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0044 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0072 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0087 0.03
Leishmania major cysteine peptidase A (CPA) 0.0057 0.0249 0.1208
Echinococcus multilocularis dnaJ subfamily B 0.0904 0.5269 0.5267
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0147 0.0784 0.6093
Brugia malayi hypothetical protein 0.0039 0.0148 0.0142
Echinococcus multilocularis cpg binding protein 0.0125 0.0658 0.0652
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0044 0.0038
Entamoeba histolytica hypothetical protein 0.0024 0.0056 0.0177
Schistosoma mansoni polycystin 1-related 0.0039 0.0148 0.0142
Echinococcus multilocularis microtubule associated protein 2 0.1532 0.8994 0.8994
Brugia malayi Cathepsin L-like precursor 0.0019 0.0025 0.0019
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0089 0.0404
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0019 0.0025 0.0019
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0135 0.0129
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0147 0.0784 0.0778
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0102 0.0096
Mycobacterium leprae conserved hypothetical protein 0.008 0.0386 0.1129
Echinococcus granulosus cathepsin l1 0.0038 0.0139 0.0133
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0352 0.2002 1
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0386 0.1893
Schistosoma mansoni inositol monophosphatase 0.004 0.0151 0.0145
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0145 0.0139
Loa Loa (eye worm) hypothetical protein 0.0147 0.0784 0.0778
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0009 0.003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0044 0.0038
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0044 0.0038
Mycobacterium ulcerans lipase LipD 0.008 0.0386 0.1306
Onchocerca volvulus 0.008 0.0386 0.126
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0147 0.0784 0.0778
Schistosoma mansoni coup transcription factor 0.0022 0.0044 0.0038
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0066 0.029
Brugia malayi hypothetical protein 0.0017 0.0016 0.001
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0043 0.0037
Schistosoma mansoni cathepsin s 0.0019 0.0025 0.0019
Brugia malayi glutathione reductase 0.0046 0.0186 0.018
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0108 0.0554 0.2738
Brugia malayi follicle stimulating hormone receptor 0.1012 0.5914 0.5911
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Brugia malayi MH2 domain containing protein 0.0248 0.1384 0.1379
Schistosoma mansoni ap endonuclease 0.0037 0.0135 0.0129
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0044 0.0038
Plasmodium falciparum thioredoxin reductase 0.0046 0.0186 0.229
Echinococcus multilocularis survival motor neuron protein 1 0.0273 0.1534 0.1528
Schistosoma mansoni lipoxygenase 0.01 0.0509 0.0503
Entamoeba histolytica cysteine protease, putative 0.0057 0.0249 0.2788
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0186 0.0608
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0135 0.0466
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0087 0.0081
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Schistosoma mansoni hypothetical protein 0.0033 0.0112 0.0106
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0135 0.3829
Echinococcus granulosus snurportin 1 0.0315 0.1778 0.1773
Plasmodium falciparum glutathione reductase 0.0046 0.0186 0.229
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0072 0.0339 0.1142
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0087 0.0595
Leishmania major glycerol uptake protein, putative 0.0147 0.0784 0.3888
Schistosoma mansoni ap endonuclease 0.0037 0.0135 0.0129
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0455 0.0449
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0044 0.0038
Toxoplasma gondii thioredoxin reductase 0.0046 0.0186 0.1395
Mycobacterium tuberculosis Probable conserved lipoprotein 0.008 0.0386 0.1293
Onchocerca volvulus 0.0038 0.0139 0.0349
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0139 0.2397
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0072 0.0339 0.1131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0087 0.03
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0249 0.0757
Brugia malayi cathepsin F-like cysteine proteinase 0.0019 0.0025 0.0019
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0147 0.0784 1
Loa Loa (eye worm) hhat protein 0.0147 0.0784 0.0778
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0015 0.0009
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0171 0.0929 0.0923
Trypanosoma brucei DNA polymerase beta thumb, putative 0.005 0.0208 0.1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0167 0.0903 0.4484
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0089 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0044 0.0038
Schistosoma mansoni cpg binding protein 0.0125 0.0658 0.0652
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0108 0.0554 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0044 0.0038
Loa Loa (eye worm) Smad1 0.0017 0.0015 0.0009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0135 0.0437
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0015 0.0009
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0072 0.0339 0.2594
Mycobacterium tuberculosis Probable hydrolase 0.008 0.0386 0.1293
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0074 0.0255
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.008 0.0386 0.038
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0286 0.0281
Brugia malayi beta-lactamase family protein 0.008 0.0386 0.038
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0056 0.0194
Schistosoma mansoni sterol O-acyltransferase 1 0.0147 0.0784 0.0778
Brugia malayi MH1 domain containing protein 0.0017 0.0015 0.0009
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0147 0.0784 0.0778
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0245 0.0239
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0151 0.1458
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0147 0.0784 0.0778
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Brugia malayi nuclear hormone receptor 0.0022 0.0044 0.0038
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0072 0.0339 1
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0147 0.0784 0.0778
Loa Loa (eye worm) glutathione reductase 0.0046 0.0186 0.018
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0147 0.0784 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.008 0.0386 0.038
Leishmania major mitochondrial DNA polymerase beta 0.0352 0.2002 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0044 0.0038
Trichomonas vaginalis porcupine, putative 0.0147 0.0784 0.2705
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.008 0.0386 0.1293
Mycobacterium tuberculosis Conserved protein 0.008 0.0386 0.1293
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0039 0.0143 0.0137
Schistosoma mansoni ran 0.0022 0.0043 0.0037
Brugia malayi cathepsin L-like precursor 0.0038 0.0139 0.0133
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0147 0.0784 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0151 0.4315
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0019
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0015 0.0009
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0056 0.0194
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0108 0.0554 0.0549
Plasmodium vivax vivapain-1 0.0029 0.0087 0.1012
Echinococcus multilocularis Smad4 0.0017 0.0015 0.0009
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0286 0.2184
Loa Loa (eye worm) acetyltransferase 0.0141 0.0749 0.0743
Leishmania major hypothetical protein, conserved 0.0147 0.0784 0.3888
Leishmania major glycerol uptake protein, putative 0.0147 0.0784 0.3888
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0208 0.1
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Leishmania major cathepsin L-like protease 0.0057 0.0249 0.1208
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.1191 0.5929
Brugia malayi Cathepsin L-like precursor 0.0057 0.0249 0.0244
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0074 0.0255
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0044 0.0038
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0066 0.02
Plasmodium vivax importin-beta 2, putative 0.0029 0.0089 0.1038
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0352 0.2002 1
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0147 0.0784 0.0778
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0139 0.1293
Brugia malayi Cathepsin L-like precursor 0.0057 0.0249 0.0244
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0043 0.0172
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.1702 1 1
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0147 0.0784 0.0778
Schistosoma mansoni zinc finger protein 0.1702 1 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0147 0.0784 0.0778
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0386 0.1332
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0279 0.1571 0.1565
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0147 0.0784 0.0778
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0044 0.0038
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0455 0.0449
Schistosoma mansoni loxhd1 0.0039 0.0148 0.0142
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Toxoplasma gondii hypothetical protein 0.0147 0.0784 0.6093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.1191 0.5929
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0286 0.0281
Brugia malayi Smad1 0.0017 0.0015 0.0009
Brugia malayi Pre-SET motif family protein 0.0422 0.2416 0.2411
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0044 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0044 0.0038
Brugia malayi beta-lactamase 0.008 0.0386 0.038
Echinococcus multilocularis expressed protein 0.0039 0.0143 0.0137
Plasmodium vivax ornithine aminotransferase, putative 0.0072 0.0339 0.4257
Schistosoma mansoni hypothetical protein 0.0039 0.0148 0.0142
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Onchocerca volvulus 0.0063 0.0286 0.0893
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0043 0.0172
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0249 0.0244
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0102 0.0096
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0151 0.0521
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0249 0.0244
Loa Loa (eye worm) hypothetical protein 0.0147 0.0784 0.0778
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0147 0.0784 1
Brugia malayi MBOAT family protein 0.0147 0.0784 0.0778
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0147 0.0784 0.0778
Schistosoma mansoni Smad4 0.0017 0.0015 0.0009
Echinococcus granulosus ubiquitin specific protease 41 0.0108 0.0554 0.0549
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0135 0.163
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0072 0.0339 0.0333
Echinococcus multilocularis smad 0.0017 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.1262 0.7392 0.739
Brugia malayi Pre-SET motif family protein 0.0063 0.0286 0.0281
Mycobacterium ulcerans hypothetical protein 0.008 0.0386 0.1306
Schistosoma mansoni hypothetical protein 0.0056 0.0245 0.0239
Plasmodium vivax glutathione reductase, putative 0.0046 0.0186 0.229
Entamoeba histolytica vacuolar protein sorting 26 0.0147 0.0784 1
Entamoeba histolytica hypothetical protein 0.0147 0.0784 1
Brugia malayi MH2 domain containing protein 0.0017 0.0015 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0784 0.2705
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0216 0.021
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0043 0.0172
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0171 0.0929 0.0923
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0147 0.0784 0.0778
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0072 0.0339 0.1131
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0087 0.0393
Loa Loa (eye worm) hypothetical protein 0.008 0.0386 0.038
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0534 0.1801
Echinococcus granulosus zinc finger protein 0.1555 0.9131 0.913
Plasmodium falciparum ornithine aminotransferase 0.0072 0.0339 0.4257
Leishmania major cathepsin L-like protease 0.0057 0.0249 0.1208
Brugia malayi Cathepsin L-like cysteine proteinase 0.0038 0.0139 0.0133
Echinococcus granulosus muscleblind protein 0.1262 0.7392 0.739
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0139 0.0479
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0147 0.0784 0.0778
Echinococcus multilocularis ubiquitin specific protease 41 0.0108 0.0554 0.0549
Leishmania major hypothetical protein, conserved 0.0027 0.0072 0.0319
Schistosoma mansoni hypothetical protein 0.0376 0.2144 0.2139
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0074 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Leishmania major cathepsin L-like protease 0.0215 0.1191 0.5929
Toxoplasma gondii ABC1 family protein 0.008 0.0386 0.2967
Brugia malayi CXXC zinc finger family protein 0.0119 0.0618 0.0612
Echinococcus multilocularis cysteine protease 0.0057 0.0249 0.0244
Brugia malayi RNA, U transporter 1 0.0084 0.0411 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0044 0.0038
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0749 0.0743
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0044 0.0038
Leishmania major GTP-binding protein, putative 0.0022 0.0043 0.0172
Schistosoma mansoni importin beta-1 0.0029 0.0089 0.0083
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0503 0.2897 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0043 0.0037
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0386 0.1332
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0249 0.0244
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0186 0.229
Brugia malayi Cathepsin L-like precursor 0.0057 0.0249 0.0244
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0249 0.0244
Entamoeba histolytica hypothetical protein 0.0026 0.0066 0.0316
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0151 0.0145
Plasmodium vivax vivapain-2 0.0057 0.0249 0.3108
Loa Loa (eye worm) inositol-1 0.004 0.0151 0.0145
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0126 0.0211
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0534 0.1801
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0066 0.029
Schistosoma mansoni hypothetical protein 0.0904 0.5269 0.5267
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0258 0.0252
Entamoeba histolytica cysteine protease, putative 0.0029 0.0087 0.0595
Echinococcus granulosus o acyltransferase membrane bound domain 0.0147 0.0784 0.0778
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0072 0.0339 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0204 0.0198
Trypanosoma cruzi glycerol uptake protein, putative 0.0147 0.0784 0.3888
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.005 0.0208 0.1
Brugia malayi Hhat protein 0.0147 0.0784 0.0778
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0044 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0286 0.0281
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0186 0.089
Leishmania major glycerol uptake protein, putative 0.0147 0.0784 0.3888
Brugia malayi MBOAT family protein 0.0147 0.0784 0.0778
Onchocerca volvulus 0.0039 0.0148 0.0383
Brugia malayi MBOAT family protein 0.0147 0.0784 0.0778
Entamoeba histolytica hypothetical protein, conserved 0.0147 0.0784 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0135 0.163
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0074 0.0255
Schistosoma mansoni survival motor neuron protein 0.0056 0.0245 0.0239
Loa Loa (eye worm) hhat protein 0.0147 0.0784 0.0778
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0108 0.0554 0.0549
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0066 0.1751
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0726 0.072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0072 0.0339 0.1142
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0108 0.0554 0.2738
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0057 0.0249 0.3108
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0548 0.0542
Schistosoma mansoni smad1 5 8 and 0.0017 0.0015 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0091 0.0455 0.0449
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0072 0.0819
Leishmania major importin beta-1 subunit, putative 0.0024 0.0056 0.0238
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Echinococcus granulosus cathepsin L 0.0029 0.0087 0.0081
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0072 0.0339 0.0333
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0151 0.0714
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0286 0.0281
Loa Loa (eye worm) hypothetical protein 0.0033 0.0112 0.0106
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0186 0.018
Loa Loa (eye worm) cysteine protease 0.0057 0.0249 0.0244
Trichomonas vaginalis esterase, putative 0.008 0.0386 0.1332
Trichomonas vaginalis rotamase, putative 0.0038 0.0138 0.0476
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0151 0.0521
Echinococcus granulosus o acyltransferase membrane bound domain 0.0147 0.0784 0.0778
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0386 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0279 0.1571 0.1565
Echinococcus granulosus neuropeptide receptor A26 0.0455 0.2609 0.2604
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0249 0.0861
Onchocerca volvulus 0.0039 0.0148 0.0383
Loa Loa (eye worm) fibroinase 0.0057 0.0249 0.0244
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0534 0.1652
Loa Loa (eye worm) hypothetical protein 0.008 0.0386 0.038
Entamoeba histolytica hypothetical protein 0.0107 0.0548 0.6815
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0102 0.0096
Brugia malayi Cathepsin L-like precursor 0.0057 0.0249 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0044 0.0038
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.008 0.0386 0.1293
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0147 0.0784 1
Leishmania major glycerol uptake protein, putative 0.0147 0.0784 0.3888
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.016 0.1952
Loa Loa (eye worm) MBOAT family protein 0.1702 1 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0169 0.0918 0.4559
Brugia malayi hypothetical protein 0.0027 0.0072 0.0066
Mycobacterium tuberculosis Conserved hypothetical protein 0.0186 0.1014 0.3446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.1191 0.5929
Leishmania major trypanothione reductase 0.0046 0.0186 0.089
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.1384 0.1379
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0044 0.0038
Plasmodium vivax unspecified product 0.0029 0.0087 0.1012
Schistosoma mansoni lipoxygenase 0.0171 0.0929 0.0923
Onchocerca volvulus 0.0057 0.0249 0.0757
Brugia malayi MBOAT family protein 0.0147 0.0784 0.0778
Trypanosoma cruzi cysteine proteinase, putative 0.0029 0.0087 0.0393
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0044 0.0038
Mycobacterium ulcerans esterase/lipase LipP 0.008 0.0386 0.1306
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0015 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0139 0.0479
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0386 0.1332
Trypanosoma cruzi GUP1, putative 0.0147 0.0784 0.3888
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0279 0.1571 0.1565
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0249 0.0244
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.1191 0.5929
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.1778 0.1773
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0254 0.1419 0.1414
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0044 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.008 0.0386 0.1293
Mycobacterium tuberculosis Probable lipase LipD 0.008 0.0386 0.1293
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0044 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0249 0.0861
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0503 0.2897 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0151 0.0714
Brugia malayi hypothetical protein 0.0039 0.0148 0.0142
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.016 0.0552
Brugia malayi diacylglycerol acyltransferase 0.0147 0.0784 0.0778
Mycobacterium ulcerans L-lysine aminotransferase 0.0072 0.0339 0.1142
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0108 0.0554 0.2738
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0135 0.2314
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0044 0.0038
Brugia malayi Cathepsin L-like precursor 0.0038 0.0139 0.0133
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0072 0.0339 0.1142
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0603 0.1896
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0386 0.038
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0043 0.0444
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0046 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0102 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0784 0.2705
Echinococcus multilocularis cathepsin L 0.0029 0.0087 0.0081
Entamoeba histolytica cysteine proteinase 2 0.0029 0.0087 0.0595
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0135 0.1241
Onchocerca volvulus 0.0056 0.0245 0.074
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0015 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0044 0.0038
Schistosoma mansoni inositol monophosphatase 0.004 0.0151 0.0145
Entamoeba histolytica hypothetical protein 0.0107 0.0548 0.6815
Loa Loa (eye worm) hypothetical protein 0.0063 0.0286 0.0281
Echinococcus granulosus beta LACTamase domain containing family member 0.008 0.0386 0.038
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0503 0.2897 1
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0148 0.1796
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0038

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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