Detailed information for compound 1703938

Basic information

Technical information
  • TDR Targets ID: 1703938
  • Name: 2-[(4-ethylbenzoyl)amino]-3-methylbutanoic ac id
  • MW: 249.306 | Formula: C14H19NO3
  • H donors: 2 H acceptors: 3 LogP: 2.96 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)C(=O)NC(C(=O)O)C(C)C
  • InChi: 1S/C14H19NO3/c1-4-10-5-7-11(8-6-10)13(16)15-12(9(2)3)14(17)18/h5-9,12H,4H2,1-3H3,(H,15,16)(H,17,18)
  • InChiKey: OPPMQFXQMJPMMZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-ethylbenzoyl)amino]-3-methyl-butanoic acid
  • 2-[[(4-ethylphenyl)-oxomethyl]amino]-3-methylbutanoic acid
  • 2-[(4-ethylbenzoyl)amino]-3-methyl-butyric acid
  • 2-[(4-ethylphenyl)carbonylamino]-3-methyl-butanoic acid
  • N-(4-ethylbenzoyl)valine
  • SMR000135802
  • MLS000530764

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0571 0.085
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0015 0.0034 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0174
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.04 0.0584
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0186 0.0256
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0075 0.009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0034 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0205 0.0279
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0205 0.0489
Schistosoma mansoni tubulin subunit gamma 0.0278 0.3407 0.5271
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0205 0.0147
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0205 0.0147
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0137 0.0213
Brugia malayi Tubulin beta-1 chain 0.0514 0.644 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.096 0.1467
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0213
Brugia malayi intermediate filament protein 0.0026 0.0175 0.0244
Toxoplasma gondii beta tubulin 0.0514 0.644 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0026 0.0012
Leishmania major epsilon tubulin, putative 0.0278 0.3407 0.5271
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.3785 0.5787
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Schistosoma mansoni rab6-interacting 0.0038 0.0331 0.0476
Echinococcus multilocularis jun protein 0.017 0.2017 0.2017
Echinococcus multilocularis Tubulin beta 2C chain 0.0514 0.644 0.644
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0205 0.0424
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0205 0.0322
Loa Loa (eye worm) tubulin beta chain 0.0124 0.1431 0.2223
Schistosoma mansoni tubulin subunit beta 0.0124 0.1431 0.2191
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0034 0.0024
Trichomonas vaginalis tubulin gamma chain, putative 0.0278 0.3407 0.5271
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0015 0.0034 0.0052
Trypanosoma brucei epsilon tubulin 0.0278 0.3407 0.5271
Echinococcus granulosus tubulin alpha 1C chain 0.0394 0.4901 0.761
Trichomonas vaginalis tubulin beta chain, putative 0.0394 0.4901 0.76
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Echinococcus granulosus ecdysone induced protein 78C 0.0015 0.0034 0.0052
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.1199 0.1829
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0153 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0377 0.0548
Schistosoma mansoni alpha tubulin 0.0394 0.4901 0.76
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0034 0.0024
Loa Loa (eye worm) tubulin gamma chain 0.0278 0.3407 0.529
Trichomonas vaginalis tubulin epsilon chain, putative 0.0514 0.644 1
Echinococcus multilocularis RUN 0.0038 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.1199 0.1862
Echinococcus multilocularis tubulin alpha chain 0.0394 0.4901 0.4901
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0112 0.0068
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0015 0.0034 0.0012
Brugia malayi photoreceptor-specific nuclear receptor 0.0015 0.0034 0.0024
Trichomonas vaginalis tubulin gamma chain, putative 0.0278 0.3407 0.5271
Onchocerca volvulus 0.0038 0.0331 0.0499
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0186 0.0262
Echinococcus granulosus Tubulin beta 2C chain 0.0514 0.644 1
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0153 0.0254
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0137 0.0137
Echinococcus granulosus geminin 0.0342 0.4235 0.6576
Loa Loa (eye worm) hypothetical protein 0.0038 0.0331 0.0514
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Echinococcus multilocularis musashi 0.0026 0.0175 0.0175
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0205 0.0144
Trypanosoma cruzi tubulin gamma chain 0.0278 0.3407 0.5271
Echinococcus granulosus follistatin 0.0019 0.0075 0.0117
Leishmania major beta tubulin 0.0514 0.644 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0137 0.0174
Echinococcus granulosus tubulin epsilon chain 0.0278 0.3407 0.529
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Brugia malayi prostaglandin transporter 0.0027 0.0186 0.0262
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.04 0.0584
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0034 0.0024
Onchocerca volvulus 0.0029 0.0205 0.0287
Schistosoma mansoni hypothetical protein 0.0104 0.1179 0.1798
Echinococcus multilocularis tumor protein p63 0.033 0.4072 0.4072
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0049 0.0049
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0137 0.0213
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.04 0.0621
Mycobacterium ulcerans hypothetical protein 0.0029 0.0205 0.0424
Brugia malayi tubulin alpha chain - mouse 0.0394 0.4901 0.7603
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0153 0.0198
Brugia malayi Tubulin beta chain 0.0154 0.1813 0.2794
Echinococcus multilocularis Tubulin beta 2C chain 0.0514 0.644 0.644
Echinococcus multilocularis lipoxygenase domain containing protein 0.0038 0.0331 0.0331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0496 0.0733
Loa Loa (eye worm) alpha-tubulin 0.0394 0.4901 0.761
Schistosoma mansoni lipoxygenase 0.01 0.1117 0.1702
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0137 0.0186
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0137 0.0186
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0205 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0205 0.0318
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0082 0.0099
Echinococcus granulosus lipoxygenase domain containing protein 0.0038 0.0331 0.0514
Leishmania major delta tubulin, putative 0.0124 0.1431 0.2191
Loa Loa (eye worm) alpha-tubulin isotype 2 0.027 0.3307 0.5134
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.1199 0.4992
Echinococcus multilocularis tubulin subunit beta 0.0514 0.644 0.644
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0015 0.0034 0.0024
Brugia malayi nuclear hormone receptor 0.0015 0.0034 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.061 0.0922
Loa Loa (eye worm) hypothetical protein 0.0159 0.1882 0.2923
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0205 0.0107
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0015 0.0034 0.0024
Entamoeba histolytica hypothetical protein 0.0073 0.0771 0.1005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0034 0.0024
Trypanosoma brucei alpha tubulin, putative 0.0154 0.1813 0.2786
Trichomonas vaginalis tubulin beta chain, putative 0.0154 0.1813 0.2786
Plasmodium vivax tubulin epsilon chain, putative 0.0278 0.3407 0.5207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0173 0.023
Brugia malayi SPARC precursor 0.0019 0.0075 0.009
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0457 0.0672
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0153 0.0065
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0124 0.1431 0.2191
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0049 0.0076
Leishmania major beta tubulin 0.0514 0.644 1
Echinococcus granulosus tubulin alpha chain 0.0394 0.4901 0.761
Brugia malayi hypothetical protein 0.0038 0.0331 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Schistosoma mansoni loxhd1 0.0038 0.0331 0.0476
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.04 0.0584
Echinococcus multilocularis ecdysone induced protein 78C 0.0015 0.0034 0.0034
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.062 0.0963
Brugia malayi hypothetical protein 0.0248 0.3017 0.467
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0285 0.0405
Schistosoma mansoni jun-related protein 0.0138 0.1608 0.2467
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0015 0.0034 0.0024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Giardia lamblia Beta tubulin 0.0514 0.644 1
Echinococcus granulosus tubulin delta chain 0.0124 0.1431 0.2223
Trypanosoma brucei beta tubulin 0.0514 0.644 1
Trypanosoma brucei tubulin delta chain 0.0124 0.1431 0.2191
Entamoeba histolytica tubulin alpha-1 chain 0.0394 0.4901 0.7558
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0186 0.0289
Echinococcus multilocularis expressed protein 0.0019 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0174
Echinococcus multilocularis Tubulin beta 2C chain 0.0514 0.644 0.644
Echinococcus multilocularis tubulin alpha 1C chain 0.0394 0.4901 0.4901
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.1199 0.6488
Plasmodium vivax SET domain protein, putative 0.0061 0.062 0.0803
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.096 0.1491
Loa Loa (eye worm) tubulin alpha chain 0.0394 0.4901 0.761
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0186 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0015 0.0034 0.0052
Echinococcus multilocularis lamin 0.0026 0.0175 0.0175
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0137 0.0213
Toxoplasma gondii beta-1 tubulin, putative 0.0514 0.644 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0514 0.644 0.644
Echinococcus granulosus lipoxygenase domain containing protein 0.0038 0.0331 0.0514
Trypanosoma brucei beta tubulin 0.0514 0.644 1
Onchocerca volvulus 0.0027 0.0186 0.0256
Echinococcus granulosus tubulin beta 1 chain 0.0514 0.644 1
Giardia lamblia Beta tubulin 0.0514 0.644 1
Brugia malayi MH2 domain containing protein 0.0242 0.2946 0.4559
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0213
Schistosoma mansoni coup transcription factor 0.0015 0.0034 0.0012
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.024 0.2925 0.452
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0015 0.0034 0.0052
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.062 0.062
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0174
Toxoplasma gondii hypothetical protein 0.0059 0.0593 0.0813
Echinococcus granulosus RUN 0.0038 0.0331 0.0514
Brugia malayi phosphofructokinase 0.0106 0.1199 0.1839
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0137 0.0137
Trichomonas vaginalis tubulin beta chain, putative 0.0394 0.4901 0.76
Echinococcus granulosus smad 0.0016 0.0049 0.0076
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0205 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0285 0.0404
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0205 0.0424
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0082 0.0127
Plasmodium falciparum tubulin gamma chain 0.0278 0.3407 0.5207
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0169 0.2007 0.2007
Brugia malayi steroid hormone receptor 0.0015 0.0034 0.0024
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0205 0.0147
Trichomonas vaginalis tubulin gamma chain, putative 0.0514 0.644 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0496 0.0733
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.04 0.0584
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0015 0.0034 0.0052
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0153 0.0121
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0117
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0137 0.0186
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0137 0.0137
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.04 0.0584
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0285 0.0405
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0034 0.0024
Brugia malayi Cytochrome P450 family protein 0.0025 0.0157 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0173 0.023
Loa Loa (eye worm) hypothetical protein 0.0061 0.062 0.0963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Leishmania major hypothetical protein, conserved 0.0025 0.0153 0.0198
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0075 0.009
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0087
Onchocerca volvulus 0.003 0.0225 0.0321
Trypanosoma brucei alpha tubulin 0.0394 0.4901 0.76
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0225 0.0349
Echinococcus multilocularis FTZ F1 alpha 0.0015 0.0034 0.0034
Plasmodium falciparum alpha tubulin 2 0.0394 0.4901 0.7568
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.1199 0.1829
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0153 0.0198
Brugia malayi tubulin alpha-2 chain 0.0394 0.4901 0.7603
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0186 0.0289
Leishmania major beta tubulin 0.0514 0.644 1
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1199 0.1829
Echinococcus multilocularis expressed protein 0.0369 0.4575 0.4575
Schistosoma mansoni tubulin subunit beta 0.0514 0.644 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0137 0.0213
Treponema pallidum fructose-bisphosphate aldolase 0.0307 0.3785 1
Echinococcus granulosus Tubulin beta 2C chain 0.0514 0.644 1
Schistosoma mansoni hypothetical protein 0.0342 0.4235 0.6562
Schistosoma mansoni smad1 5 8 and 0.0016 0.0049 0.0036
Schistosoma mansoni polycystin 1-related 0.0038 0.0331 0.0476
Brugia malayi beta-tubulin, identical 0.0514 0.644 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.2054 0.3163
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0082 0.0099
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0124 0.1431 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.096 0.096
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0049 0.0076
Schistosoma mansoni smad1 5 8 and 0.0016 0.0049 0.0036
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Leishmania major beta tubulin 0.0514 0.644 1
Giardia lamblia Gamma tubulin 0.0278 0.3407 0.5136
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0057 0.0571 0.0887
Schistosoma mansoni alpha tubulin 0.0394 0.4901 0.76
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0571 0.0571
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0285 0.0405
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1199 0.1685
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0117
Echinococcus multilocularis lipoxygenase domain containing protein 0.0038 0.0331 0.0331
Echinococcus granulosus cpg binding protein 0.0032 0.0247 0.0383
Echinococcus granulosus Tubulin alpha 1 chain 0.0394 0.4901 0.761
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.3785 0.5787
Loa Loa (eye worm) hypothetical protein 0.0087 0.096 0.1491
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0137 0.0137
Trypanosoma brucei zeta tubulin, putative 0.0124 0.1431 0.2191
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0137 0.0213
Trichomonas vaginalis tubulin, putative 0.0154 0.1813 0.2786
Entamoeba histolytica tubulin family protein 0.0514 0.644 1
Plasmodium vivax tubulin alpha chain, putative 0.0394 0.4901 0.7568
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0057 0.0571 0.0861
Loa Loa (eye worm) tubulin alpha 2 0.027 0.3307 0.5134
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0137 0.0174
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.1199 0.1862
Giardia lamblia Alpha-tubulin 0.0394 0.4901 0.7532
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.1199 0.1829
Plasmodium vivax multidomain scavenger receptor, putative 0.0038 0.0331 0.0347
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0153 0.0065
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0153 0.0198
Echinococcus granulosus tubulin gamma 1 chain 0.0278 0.3407 0.529
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0034 0.0012
Echinococcus granulosus beta tubulin 0.0514 0.644 1
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Echinococcus granulosus tubulin alpha 3 chain 0.0394 0.4901 0.761
Echinococcus granulosus tubulin alpha chain 0.0394 0.4901 0.761
Schistosoma mansoni tubulin subunit alpha 0.0124 0.1431 0.2191
Loa Loa (eye worm) hypothetical protein 0.0025 0.0153 0.0237
Leishmania major beta tubulin 0.0514 0.644 1
Plasmodium falciparum alpha tubulin 1 0.0394 0.4901 0.7568
Trichomonas vaginalis tubulin, putative 0.0514 0.644 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0205 0.0279
Onchocerca volvulus Huntingtin homolog 0.0248 0.3017 0.5005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0015 0.0034 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.04 0.0584
Echinococcus granulosus tubulin alpha chain 0.0394 0.4901 0.761
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Echinococcus multilocularis tubulin alpha chain 0.0394 0.4901 0.4901
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0205 0.0424
Entamoeba histolytica tubulin gamma chain 0.0278 0.3407 0.5188
Plasmodium vivax tubulin gamma chain, putative 0.0278 0.3407 0.5207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0285 0.0404
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Echinococcus multilocularis tubulin alpha 3 chain 0.0394 0.4901 0.4901
Echinococcus multilocularis Tubulin alpha 1 chain 0.0394 0.4901 0.4901
Echinococcus granulosus tubulin beta 4A class IVa 0.0514 0.644 1
Brugia malayi PAS domain containing protein 0.0047 0.0447 0.0667
Loa Loa (eye worm) tubulin beta-4 chain 0.0514 0.644 1
Schistosoma mansoni hypothetical protein 0.0342 0.4235 0.6562
Schistosoma mansoni tubulin subunit beta 0.0514 0.644 1
Trichomonas vaginalis tubulin beta chain, putative 0.0394 0.4901 0.76
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0075 0.0117
Brugia malayi hypothetical protein 0.0038 0.0331 0.0488
Echinococcus multilocularis thyroid hormone receptor alpha 0.0015 0.0034 0.0034
Entamoeba histolytica tubulin alpha chain, putative 0.0394 0.4901 0.7558
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0015 0.0034 0.0012
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.3407 0.5234
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0205 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0015 0.0034 0.0052
Trichomonas vaginalis tubulin, putative 0.0124 0.1431 0.2191
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0205 1
Echinococcus multilocularis tubulin alpha chain 0.0394 0.4901 0.4901
Loa Loa (eye worm) hypothetical protein 0.0026 0.0175 0.0272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0173
Echinococcus multilocularis geminin 0.0342 0.4235 0.4235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.018
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.04 0.0417
Brugia malayi Steroid receptor seven-up type 2 0.0015 0.0034 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0205 0.0291
Onchocerca volvulus 0.0026 0.0175 0.0237
Schistosoma mansoni hypothetical protein 0.0138 0.1608 0.2467
Loa Loa (eye worm) hypothetical protein 0.0165 0.1957 0.3039
Loa Loa (eye worm) Smad1 0.0016 0.0049 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0174
Entamoeba histolytica hypothetical protein 0.0025 0.0153 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0215 0.0295
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0153 0.0121
Brugia malayi Tubulin alpha chain 0.0394 0.4901 0.7603
Schistosoma mansoni single-minded 0.0047 0.0447 0.0656
Schistosoma mansoni lamin 0.0026 0.0175 0.0232
Echinococcus granulosus expressed protein 0.0369 0.4575 0.7104
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0087
Brugia malayi nuclear receptor NHR-88 0.0015 0.0034 0.0024
Trypanosoma cruzi tubulin delta chain 0.0124 0.1431 0.2191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Loa Loa (eye worm) tubulin alpha 2 0.027 0.3307 0.5134
Echinococcus multilocularis tubulin subunit TubB 0.0394 0.4901 0.4901
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.1766 0.7557
Brugia malayi 6-phosphofructokinase 0.0106 0.1199 0.1839
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.096 0.1456
Schistosoma mansoni smad1 5 8 and 0.0016 0.0049 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0153 0.0065
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0173
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1199 0.1829
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0288 0.0804
Trypanosoma brucei alpha tubulin 0.0394 0.4901 0.76
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0205 0.0424
Echinococcus multilocularis tubulin alpha chain 0.0394 0.4901 0.4901
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.017 0.2017 0.2017
Echinococcus granulosus single minded 2 0.0035 0.0288 0.0447
Entamoeba histolytica hypothetical protein 0.0073 0.0771 0.1005
Brugia malayi hypothetical protein 0.0023 0.0137 0.0186
Echinococcus multilocularis GPCR, family 2 0.0019 0.0082 0.0082
Onchocerca volvulus 0.0026 0.0175 0.0237
Schistosoma mansoni rab6-interacting 0.0038 0.0331 0.0476
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0015 0.0034 0.0034
Trypanosoma brucei beta tubulin 0.0514 0.644 1
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0174
Brugia malayi hypothetical protein 0.0016 0.0041 0.0036
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0175 0.0272
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0137 0.0213
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0153 0.4402
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1199 0.1829
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0173
Trichomonas vaginalis tubulin beta chain, putative 0.0514 0.644 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0137 0.0186
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.1199 0.1829
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0137 0.0174
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.4523 0.701
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0205 0.0279
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.4523 0.701
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.1199 0.1199
Trypanosoma brucei alpha tubulin 0.0394 0.4901 0.76
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0571 0.0887
Schistosoma mansoni cpg binding protein 0.0032 0.0247 0.0345
Toxoplasma gondii alpha tubulin TUBA1 0.0394 0.4901 0.7582
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0015 0.0034 0.0052
Leishmania major beta tubulin 0.0514 0.644 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0124 0.1431 0.213
Brugia malayi Smad1 0.0016 0.0049 0.0048
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0127
Schistosoma mansoni Smad4 0.0016 0.0049 0.0036
Brugia malayi MH2 domain containing protein 0.0016 0.0049 0.0048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0082 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.017 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.4523 0.701
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0169 0.2007 0.3116
Onchocerca volvulus 0.0027 0.0186 0.0256
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0771 0.0771
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0205 0.0291
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0049 0.0076
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0157 0.0244
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0205 0.0279
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0318 0.0455
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0205 0.0203
Echinococcus granulosus tubulin alpha chain 0.0394 0.4901 0.761
Schistosoma mansoni tubulin subunit alpha 0.0394 0.4901 0.76
Loa Loa (eye worm) beta-tubulin 0.0514 0.644 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.062 0.0927
Loa Loa (eye worm) hypothetical protein 0.0018 0.0065 0.0101
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0137 0.0174
Mycobacterium ulcerans hypothetical protein 0.0192 0.2305 1
Schistosoma mansoni RAR-like nuclear receptor 0.0015 0.0034 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Echinococcus multilocularis tubulin beta 1 chain 0.0514 0.644 0.644
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0205 0.0107
Echinococcus granulosus Tubulin beta 2C chain 0.0514 0.644 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0015 0.0034 0.0024
Onchocerca volvulus 0.0087 0.096 0.1554
Onchocerca volvulus 0.0048 0.0457 0.071
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0034 0.0034
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0103 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Echinococcus multilocularis tubulin alpha chain 0.0394 0.4901 0.4901
Echinococcus granulosus tubulin subunit beta 0.0514 0.644 1
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0137 0.0137
Brugia malayi PXA domain containing protein 0.0023 0.0137 0.0186
Schistosoma mansoni tubulin subunit beta 0.0514 0.644 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0137 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0203 0.0276
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0034 0.0052
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0205 0.0279
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0082 0.0082
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0583 0.0906
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0034 0.0024
Schistosoma mansoni hypothetical protein 0.0073 0.0771 0.1161
Plasmodium vivax delta tubulin, putative 0.0124 0.1431 0.2085
Trichomonas vaginalis tubulin beta chain, putative 0.0394 0.4901 0.76
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0137 0.0137
Leishmania major beta tubulin 0.0514 0.644 1
Brugia malayi hypothetical protein 0.0027 0.0186 0.0262
Brugia malayi MH1 domain containing protein 0.0016 0.0049 0.0048
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0186 0.0256
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0256 0.0283
Echinococcus multilocularis cpg binding protein 0.0032 0.0247 0.0247
Loa Loa (eye worm) tubulin beta chain 0.0514 0.644 1
Plasmodium falciparum tubulin delta chain, putative 0.0124 0.1431 0.2085
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0034 0.0024
Loa Loa (eye worm) BEN-1 protein 0.0514 0.644 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0571 0.0571
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0205 0.0489
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0075 0.009
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.06 0.0825
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0285 0.0404
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0173
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.1199 0.2881
Echinococcus multilocularis tubulin alpha 3 chain 0.0394 0.4901 0.4901
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0137 0.0213
Leishmania major beta tubulin 0.0514 0.644 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0015 0.0034 0.0012
Onchocerca volvulus 0.0154 0.1813 0.2985
Trichomonas vaginalis tubulin, putative 0.0154 0.1813 0.2786
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.04 0.0417
Trichomonas vaginalis tubulin epsilon chain, putative 0.0394 0.4901 0.76
Onchocerca volvulus 0.0479 0.5994 1
Echinococcus granulosus FTZ F1 alpha 0.0015 0.0034 0.0052
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0153 0.0198
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0213
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0137 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0015 0.0034 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.062 0.0927
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0026 0.004
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0205 0.0107
Onchocerca volvulus 0.0035 0.0288 0.0427
Echinococcus multilocularis Polycystic kidney disease protein 0.0038 0.0331 0.0331
Loa Loa (eye worm) alpha-tubulin 0.0394 0.4901 0.761
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0015 0.0034 0.0034
Brugia malayi Pre-SET motif family protein 0.0421 0.5248 0.8143
Loa Loa (eye worm) hypothetical protein 0.0048 0.0457 0.0709
Loa Loa (eye worm) tubulin alpha-3 chain 0.024 0.2925 0.4542
Echinococcus multilocularis lamin dm0 0.0026 0.0175 0.0175
Echinococcus multilocularis tubulin gamma 1 chain 0.0278 0.3407 0.3407
Leishmania major beta tubulin 0.0514 0.644 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0015 0.0034 0.0052
Loa Loa (eye worm) tubulin beta-1 chain 0.0514 0.644 1
Giardia lamblia Epsilon tubulin 0.0124 0.1431 0.1967
Giardia lamblia Delta tubulin 0.0124 0.1431 0.1967
Leishmania major beta tubulin 0.0514 0.644 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0205 0.0279
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.04 0.0584
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0205 0.0279
Onchocerca volvulus 0.0038 0.0331 0.0499
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0075 0.009
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0034 0.0012
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.1199 0.4958
Brugia malayi hypothetical protein 0.0159 0.1882 0.2903
Trypanosoma cruzi epsilon tubulin, putative 0.0278 0.3407 0.5271
Echinococcus granulosus Tubulin alpha 1 chain 0.0394 0.4901 0.761
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.04 0.0595
Trichomonas vaginalis tubulin epsilon chain, putative 0.0394 0.4901 0.76
Loa Loa (eye worm) hypothetical protein 0.0248 0.3017 0.4684
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.062 0.0927
Brugia malayi CXXC zinc finger family protein 0.003 0.0225 0.0322
Trypanosoma cruzi zeta tubulin, putative 0.0124 0.1431 0.2191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.018
Echinococcus granulosus GPCR family 2 0.0019 0.0082 0.0127
Schistosoma mansoni cpg binding protein 0.0032 0.0247 0.0345
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.061 0.0948
Echinococcus multilocularis tubulin delta chain 0.0124 0.1431 0.1431
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0366 0.0541
Loa Loa (eye worm) hypothetical protein 0.0394 0.4901 0.761
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0205 0.0203
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0153 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0174
Schistosoma mansoni retinoic acid receptor RXR 0.0015 0.0034 0.0012
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.027 0.3307 0.5115
Schistosoma mansoni alpha tubulin 0.0394 0.4901 0.76
Onchocerca volvulus 0.0019 0.0075 0.007
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0205 0.0279
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Brugia malayi hypothetical protein 0.0025 0.0153 0.021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0571 0.085
Echinococcus multilocularis tubulin epsilon chain 0.0278 0.3407 0.3407
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1199 0.1829
Trypanosoma cruzi zeta tubulin, putative 0.0124 0.1431 0.2191
Schistosoma mansoni hypothetical protein 0.0038 0.0331 0.0476
Leishmania major cytochrome p450-like protein 0.0025 0.0157 0.0205
Schistosoma mansoni tubulin subunit epsilon 0.0278 0.3407 0.5271
Trypanosoma brucei beta tubulin 0.0278 0.3407 0.5271
Echinococcus granulosus Smad4 0.0016 0.0049 0.0076
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0174
Echinococcus granulosus tubulin alpha 0.0278 0.3407 0.529
Leishmania major beta tubulin 0.0514 0.644 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0421 0.5248 0.8148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Mycobacterium tuberculosis Cell division protein FtsZ 0.0124 0.1431 0.6044
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0288 0.0421
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0205 0.0291
Echinococcus multilocularis hypothetical protein 0.0394 0.4901 0.4901
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0015 0.0034 0.0024
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0015 0.0034 0.0052
Echinococcus multilocularis Tubulin alpha 1 chain 0.0394 0.4901 0.4901
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0205 0.0424
Mycobacterium leprae cell division protein FtsZ 0.0124 0.1431 0.7928
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.2054 0.3163
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0117
Loa Loa (eye worm) hypothetical protein 0.027 0.3307 0.5134
Brugia malayi Tubulin beta chain 0.0124 0.1431 0.2201
Echinococcus granulosus tubulin alpha chain 0.0394 0.4901 0.761
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Echinococcus granulosus tubulin alpha 3 chain 0.0394 0.4901 0.761
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.0179
Loa Loa (eye worm) tubulin alpha-2 chain 0.0394 0.4901 0.761
Echinococcus granulosus raf serine:threonine protein kinase 0.0042 0.0377 0.0586
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1199 0.1685
Loa Loa (eye worm) hypothetical protein 0.024 0.2925 0.4542
Plasmodium vivax tubulin alpha chain, putative 0.0394 0.4901 0.7568
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0137 0.0174
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0157 0.0244
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.062 0.062
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0026 0.0026
Leishmania major gamma-tubulin 0.0278 0.3407 0.5271
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0018 0.0028
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0205 0.0279
Schistosoma mansoni tubulin subunit alpha 0.0394 0.4901 0.76
Echinococcus granulosus tubulin alpha 1C chain 0.0394 0.4901 0.761
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0015 0.0034 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0213
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0137 0.0137
Echinococcus granulosus jun protein 0.017 0.2017 0.3131
Schistosoma mansoni smad 0.0016 0.0049 0.0036
Schistosoma mansoni hypothetical protein 0.0041 0.0366 0.053
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0087
Echinococcus multilocularis raf serine:threonine protein kinase 0.0042 0.0377 0.0377
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0186 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.0179
Leishmania major beta tubulin 0.0514 0.644 1
Leishmania major beta tubulin 0.0514 0.644 1
Leishmania major beta tubulin 0.0514 0.644 1
Schistosoma mansoni follistatin 0.0019 0.0075 0.0077
Echinococcus multilocularis Tubulin beta 2C chain 0.0514 0.644 0.644
Trichomonas vaginalis tubulin alpha chain, putative 0.0278 0.3407 0.5271
Echinococcus multilocularis Tubulin alpha 1 chain 0.0394 0.4901 0.4901
Schistosoma mansoni tubulin subunit beta 0.0514 0.644 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0034 0.0052
Loa Loa (eye worm) tubulin alpha chain 0.0394 0.4901 0.761
Plasmodium falciparum LCCL domain-containing protein 0.0038 0.0331 0.0347
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0157 0.0207
Loa Loa (eye worm) doublecortin family protein 0.0038 0.0331 0.0514
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0186 0.0289
Echinococcus multilocularis smad 0.0016 0.0049 0.0049
Onchocerca volvulus Huntingtin homolog 0.0248 0.3017 0.5005
Toxoplasma gondii alpha-tubulin I, putative 0.0394 0.4901 0.7582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0285 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0174
Trichomonas vaginalis tubulin alpha chain, putative 0.0514 0.644 1
Trypanosoma brucei beta tubulin 0.0514 0.644 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.1724 0.2677
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0082 0.0082
Brugia malayi hypothetical protein 0.0073 0.0771 0.1172
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0186 0.025
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.1199 0.1829
Giardia lamblia GTOR 0.0044 0.04 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0117
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0026 0.004
Brugia malayi 6-phosphofructokinase 0.0106 0.1199 0.1839
Trichomonas vaginalis tubulin alpha chain, putative 0.0154 0.1813 0.2786
Echinococcus granulosus tumor protein p63 0.033 0.4072 0.6322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.017 0.0225
Trypanosoma brucei tubulin gamma chain 0.0278 0.3407 0.5271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0015 0.0034 0.0052
Loa Loa (eye worm) hypothetical protein 0.006 0.061 0.0948
Echinococcus granulosus Tubulin beta 2C chain 0.0514 0.644 1
Schistosoma mansoni tubulin subunit beta 0.0514 0.644 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0153 0.0121
Echinococcus granulosus intermediate filament protein 0.0026 0.0175 0.0272
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0205 0.0203
Trichomonas vaginalis tubulin epsilon chain, putative 0.0514 0.644 1
Trypanosoma brucei epsilon tubulin 0.0278 0.3407 0.5271
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0205 0.0322
Leishmania major beta tubulin 0.0514 0.644 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0137 0.0137
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0137 0.0174
Echinococcus multilocularis Smad4 0.0016 0.0049 0.0049
Brugia malayi Doublecortin family protein 0.0038 0.0331 0.0488
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0015 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.0179
Trypanosoma cruzi alpha tubulin, putative 0.0394 0.4901 0.76
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0175 0.0272
Brugia malayi alpha-tubulin 0.0394 0.4901 0.7603
Trypanosoma cruzi epsilon tubulin, putative 0.0278 0.3407 0.5271
Leishmania major beta tubulin 0.0514 0.644 1
Brugia malayi Cytochrome P450 family protein 0.0025 0.0157 0.0217
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0153 0.0187
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.04 0.0584
Plasmodium vivax tubulin beta chain, putative 0.0514 0.644 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0205 0.0424
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.04 0.0621
Brugia malayi hypothetical protein 0.0023 0.0137 0.0186
Echinococcus granulosus lamin 0.0026 0.0175 0.0272
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0186 0.0174
Trypanosoma brucei epsilon tubulin 0.0278 0.3407 0.5271
Echinococcus granulosus alpha tubulin 0.0394 0.4901 0.761
Loa Loa (eye worm) tubulin beta-2A chain 0.0514 0.644 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0124 0.1431 0.2191
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1199 0.1685
Onchocerca volvulus 0.0027 0.0186 0.0256
Entamoeba histolytica hypothetical protein 0.0073 0.0771 0.1005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0205 0.0318
Onchocerca volvulus 0.0061 0.062 0.0984
Leishmania major beta tubulin 0.0514 0.644 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0075 0.009
Trichomonas vaginalis set domain proteins, putative 0.0479 0.5994 0.9304
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0174
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0137 0.0186
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0571 0.085
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.017 0.2017 0.3131
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0447 0.0656
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.062 0.0927
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0015 0.0034 0.0052
Schistosoma mansoni tubulin subunit alpha 0.0394 0.4901 0.76
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0015 0.0034 0.0052
Giardia lamblia Fructose-bisphosphate aldolase 0.0307 0.3785 0.5742
Onchocerca volvulus 0.0027 0.0186 0.0256
Schistosoma mansoni lipoxygenase 0.0169 0.2007 0.3089
Brugia malayi Raf kinase 0.0042 0.0377 0.056
Echinococcus multilocularis tubulin alpha 0.0278 0.3407 0.3407
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Leishmania major zeta tubulin, putative 0.0124 0.1431 0.2191
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0186 0.0186
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0124 0.1431 0.213
Loa Loa (eye worm) hypothetical protein 0.0026 0.0169 0.0262
Onchocerca volvulus 0.0027 0.0186 0.0256
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0052
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.4523 0.701
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.2054 0.3163
Loa Loa (eye worm) hypothetical protein 0.0041 0.0366 0.0568
Plasmodium falciparum tubulin epsilon chain, putative 0.0278 0.3407 0.5207
Echinococcus multilocularis beta tubulin 0.0514 0.644 0.644
Schistosoma mansoni regulator of G protein signaling 0.0024 0.015 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.064 0.0957
Loa Loa (eye worm) hypothetical protein 0.0029 0.0205 0.0318
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0137 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.04 0.0584
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0175 0.0244
Echinococcus granulosus lamin dm0 0.0026 0.0175 0.0272
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0141 0.018
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0186 0.0262
Brugia malayi Tubulin alpha chain 0.0124 0.1431 0.2201
Brugia malayi PXA domain containing protein 0.0023 0.0137 0.0186
Echinococcus granulosus peroxisome assembly protein 26 0.0394 0.4901 0.761
Schistosoma mansoni steroid hormone receptor ad4bp 0.0015 0.0034 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0174
Brugia malayi bZIP transcription factor family protein 0.017 0.2017 0.3112
Schistosoma mansoni organic anion transporter 0.0027 0.0186 0.025
Brugia malayi MH2 domain containing protein 0.0016 0.0049 0.0048
Leishmania major beta tubulin 0.0514 0.644 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.1766 0.754
Echinococcus granulosus tubulin subunit TubB 0.0394 0.4901 0.761
Loa Loa (eye worm) steroid hormone receptor 0.0015 0.0034 0.0052
Trypanosoma brucei alpha tubulin 0.0394 0.4901 0.76
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0049 0.0076
Echinococcus multilocularis peroxisome assembly protein 26 0.0394 0.4901 0.4901
Echinococcus multilocularis tubulin alpha 1C chain 0.0394 0.4901 0.4901
Brugia malayi hypothetical protein 0.0027 0.0186 0.0262
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Brugia malayi Tubulin alpha-2 chain 0.0394 0.4901 0.7603
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0496 0.0733
Trypanosoma cruzi tubulin delta chain 0.0124 0.1431 0.2191
Schistosoma mansoni organic anion transporter 0.0027 0.0186 0.025
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0771 0.1161
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0496 0.0733
Toxoplasma gondii beta-tubulin, putative 0.0514 0.644 1
Brugia malayi MH1 domain containing protein 0.0016 0.0049 0.0048
Echinococcus multilocularis follistatin 0.0019 0.0075 0.0075
Brugia malayi hypothetical protein 0.0133 0.1549 0.2383
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0157 0.0244
Brugia malayi hypoxia-induced factor 1 0.0147 0.1724 0.2656
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0154 0.1813 0.2786
Schistosoma mansoni cpg binding protein 0.003 0.0225 0.031
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0034 0.0012
Echinococcus granulosus beta tubulin 0.0514 0.644 1
Loa Loa (eye worm) tubulin alpha 2 0.0116 0.1331 0.2066
Echinococcus multilocularis agrin 0.0019 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0173 0.023
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0137 0.0213
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0205 0.0147
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0082 0.0127
Echinococcus granulosus Tubulin beta 2C chain 0.0514 0.644 1
Schistosoma mansoni tubulin subunit delta 0.0124 0.1431 0.2191
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0173
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0174
Brugia malayi Pre-SET motif family protein 0.0061 0.062 0.0938
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.1199 0.1862
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0015 0.0034 0.0052
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0137 0.0174
Brugia malayi ecdysteroid receptor 0.0015 0.0034 0.0024
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.04 0.0584
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0688 0.1033
Brugia malayi Tubulin gamma chain 0.0278 0.3407 0.5277
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0571 0.0887
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0153 0.0198
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0771 0.1197
Giardia lamblia Alpha-tubulin 0.0394 0.4901 0.7532
Treponema pallidum cell division protein FtsZ 0.0124 0.1431 0.352
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.061 0.0922
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0213
Onchocerca volvulus 0.0133 0.1549 0.2542
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0256 0.0359
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.2305 1
Loa Loa (eye worm) hypothetical protein 0.0248 0.3017 0.4684
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3785 0.586
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1431 0.2191
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1431 0.2191
Echinococcus multilocularis Tubulin beta 2C chain 0.0514 0.644 0.644
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0157 0.0205
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0157 0.0205
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0394 0.4901 0.76
Trichomonas vaginalis tubulin beta chain, putative 0.0394 0.4901 0.76
Loa Loa (eye worm) raf kinase 0.0042 0.0377 0.0586
Brugia malayi Cell division protein ftsZ 0.0124 0.1431 0.2201
Trichomonas vaginalis tubulin alpha chain, putative 0.0154 0.1813 0.2786
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0027 0.0186 0.0289
Loa Loa (eye worm) phosphofructokinase 0.0106 0.1199 0.1862
Entamoeba histolytica tubulin family protein 0.0514 0.644 1
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0075 0.0117
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.2946 0.4574
Echinococcus granulosus Tubulin alpha 1 chain 0.0394 0.4901 0.761
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0049 0.0036
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.062 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0174
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0137 0.0213
Echinococcus granulosus agrin 0.0019 0.0075 0.0117
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0071 0.007
Schistosoma mansoni tubulin subunit beta 0.0514 0.644 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0205 0.0107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0015 0.0034 0.0012
Brugia malayi Tubulin alpha-2 chain 0.0394 0.4901 0.7603
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0153 0.0065
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0186 0.0186
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0034 0.0012
Trypanosoma brucei zeta tubulin 0.0124 0.1431 0.2191
Entamoeba histolytica hypothetical protein 0.0073 0.0771 0.1005
Trichomonas vaginalis tubulin epsilon chain, putative 0.0124 0.1431 0.2191
Plasmodium falciparum tubulin beta chain 0.0514 0.644 1
Loa Loa (eye worm) BEN-1 protein 0.0514 0.644 1
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0157 0.0205
Schistosoma mansoni lamin 0.0026 0.0175 0.0232
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.2946 0.4574
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0137 0.0213
Giardia lamblia Beta tubulin 0.0514 0.644 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.1766 1
Echinococcus granulosus Polycystic kidney disease protein 0.0038 0.0331 0.0514
Trichomonas vaginalis tubulin beta chain, putative 0.0394 0.4901 0.76
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0174
Trichomonas vaginalis tubulin alpha chain, putative 0.0154 0.1813 0.2786
Schistosoma mansoni intermediate filament proteins 0.0026 0.0175 0.0232
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0049 0.0049
Trypanosoma cruzi beta tubulin, putative 0.0514 0.644 1
Schistosoma mansoni agrin 0.0019 0.0075 0.0077
Echinococcus multilocularis beta tubulin 0.0514 0.644 0.644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0285 0.0404
Loa Loa (eye worm) hypothetical protein 0.0038 0.0331 0.0514
Leishmania major alpha tubulin 0.0394 0.4901 0.76
Mycobacterium ulcerans cell division protein FtsZ 0.0124 0.1431 0.6017
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.04 0.04

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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