Detailed information for compound 1720704

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1047.37 | Formula: C61H86N6O9
  • H donors: 6 H acceptors: 8 LogP: 11.48 Rotable bonds: 29
    Rule of 5 violations (Lipinski): 3
  • SMILES: COc1cc(/C=C/C(=C(/C(=O)/C=C/c2ccc(c(c2)OC)O)\Cc2nnn(c2)CCNC(=O)COCC(=O)NCCCCN[C@H]2CC[C@]3(C(=CC[C@@H]4[C@@H]3CC[C@]3([C@H]4CC[C@@H]3[C@@H](CCCC(C)C)C)C)C2)C)/O)ccc1O
  • InChi: 1S/C61H86N6O9/c1-40(2)11-10-12-41(3)49-19-20-50-47-18-17-44-35-45(25-27-60(44,4)51(47)26-28-61(49,50)5)62-29-8-9-30-63-58(72)38-76-39-59(73)64-31-32-67-37-46(65-66-67)36-48(52(68)21-13-42-15-23-54(70)56(33-42)74-6)53(69)22-14-43-16-24-55(71)57(34-43)75-7/h13-17,21-24,33-34,37,40-41,45,47,49-51,62,68,70-71H,8-12,18-20,25-32,35-36,38-39H2,1-7H3,(H,63,72)(H,64,73)/b21-13+,22-14+,52-48-/t41-,45+,47+,49-,50+,51+,60+,61-/m1/s1
  • InChiKey: LKBWYXHGAFHRGN-HQKNYHJVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0014 0.0005
Brugia malayi tailless protein 0.001 0.0018 0.0015
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.013 0.1134
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0534 0.1175
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0084 0.019
Schistosoma mansoni hypothetical protein 0.0148 0.0849 0.1878
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0024 0.0102 0.0474
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1671 0.3964
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0014 0.0005
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0031 0.0049
Leishmania major DNA repair and recombination protein RAD54, putative 0.0024 0.0102 0.0474
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0151 0.0867 0.192
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0033 0.0025
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0018 0.0015
Schistosoma mansoni coup transcription factor 0.0021 0.0084 0.017
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0025 0.0034
Schistosoma mansoni microtubule-associated protein tau 0.0753 0.4484 1
Echinococcus granulosus RUN 0.0023 0.0095 0.0195
Echinococcus multilocularis 0.0024 0.0102 0.0094
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.016 0.0152
Schistosoma mansoni inositol monophosphatase 0.0043 0.0214 0.0461
Schistosoma mansoni hypothetical protein 0.032 0.1881 0.4186
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.1671 0.3916
Brugia malayi hypothetical protein 0.0011 0.0025 0.0034
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0018 0.001
Loa Loa (eye worm) hypothetical protein 0.0044 0.0224 0.0556
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0164 0.0942 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0643 0.3822 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Schistosoma mansoni hypothetical protein 0.0023 0.0095 0.0195
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0534 0.1175
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.0012 0.0004
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0064 0.0136
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0124 0.4455
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0018 0.001
Brugia malayi Importin beta-1 subunit 0.0029 0.013 0.0311
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0084 0.0185
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0164 0.0942 0.8193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0534 0.1175
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0025 0.0038
Toxoplasma gondii hypothetical protein 0.0026 0.0113 0.1067
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0014 0.0006
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0104 0.0215
Plasmodium falciparum importin beta, putative 0.0029 0.013 0.5427
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0084 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0084 0.019
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Echinococcus granulosus L aminoadipate semialdehyde 0.0096 0.0534 0.1175
Plasmodium vivax DNA repair protein RAD54, putative 0.0024 0.0102 0.105
Leishmania major hypothetical protein, conserved 0.0028 0.0124 0.0676
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0942 0.2457
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.016 0.034
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.1667 0.4356
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0214 0.0461
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0014 0.0006
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0018 0.0022
Brugia malayi nuclear receptor NHR-67 0.001 0.0018 0.0015
Brugia malayi nuclear receptor NHR-88 0.0021 0.0084 0.019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Trypanosoma brucei protein kinase, putative 0.0164 0.0942 0.8193
Schistosoma mansoni rab6-interacting 0.0023 0.0095 0.0195
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0084 0.017
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.1667 0.4356
Plasmodium falciparum amino acid transporter, putative 0.0026 0.0113 0.2737
Onchocerca volvulus 0.0106 0.0594 0.1524
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Schistosoma mansoni lipoxygenase 0.0095 0.0529 0.1165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0534 0.0526
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0018 0.001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.016 0.1003
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0018 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.1667 0.4356
Onchocerca volvulus 0.0096 0.0534 0.1366
Echinococcus multilocularis dnaJ subfamily B 0.0471 0.279 0.2784
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0534 0.1175
Brugia malayi hypothetical protein 0.0009 0.0014 0.0005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.012 0.3904
Loa Loa (eye worm) hypothetical protein 0.0151 0.0867 0.2245
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0795 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0164 0.0942 0.8111
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0795 0.1823
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0148 0.0849 0.0841
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0164 0.0942 0.8111
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0214 0.1864
Loa Loa (eye worm) inositol-1 0.0043 0.0214 0.0531
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0084 0.019
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0033 0.0055
Schistosoma mansoni loxhd1 0.0023 0.0095 0.0195
Schistosoma mansoni hypothetical protein 0.0148 0.0849 0.1878
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0084 0.019
Echinococcus multilocularis microtubule associated protein 2 0.0753 0.4484 0.4479
Brugia malayi N-terminal motif family protein 0.0187 0.1082 0.2807
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0643 0.3822 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0164 0.0942 0.244
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0643 0.3822 1
Brugia malayi RNA, U transporter 1 0.0081 0.0447 0.1142
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0095 0.0195
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.006 0.0117
Loa Loa (eye worm) hypothetical protein 0.007 0.038 0.0966
Schistosoma mansoni smad1 5 8 and 0.0009 0.0012 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0084 0.019
Brugia malayi hypothetical protein 0.0011 0.0025 0.0034
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0214 0.2159
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0018 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0084 0.019
Brugia malayi follicle stimulating hormone receptor 0.0464 0.275 0.7186
Brugia malayi Bromodomain containing protein 0.0076 0.0417 0.1062
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0326 0.071
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0194 0.1127 0.2594
Schistosoma mansoni hypothetical protein 0.0305 0.1792 0.3986
Onchocerca volvulus 0.0033 0.0157 0.0377
Echinococcus multilocularis L aminoadipate semialdehyde 0.0096 0.0534 0.0527
Schistosoma mansoni Smad4 0.0009 0.0012 0.0009
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0113 0.0105
Loa Loa (eye worm) hypothetical protein 0.0096 0.0534 0.137
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0113 0.0234
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0643 0.3822 0.938
Schistosoma mansoni nuclear hormone receptor 0.001 0.0018 0.0022
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0095 0.0087
Brugia malayi MAP kinase sur-1 0.0164 0.0942 0.244
Brugia malayi hypothetical protein 0.0023 0.0095 0.0218
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0026 0.0113 0.0265
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0084 0.017
Echinococcus granulosus DNA repair and recombination protein RAD54B 0.0024 0.0102 0.021
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.0265
Entamoeba histolytica hypothetical protein 0.004 0.0197 0.0249
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0643 0.3822 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0096 0.0534 0.1175
Echinococcus granulosus flap endonuclease 1 0.0028 0.013 0.0272
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0113 0.0234
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0164 0.0942 0.8111
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.1667 0.4356
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0084 0.019
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0084 0.019
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.002 0.0012
Loa Loa (eye worm) type III restriction enzyme 0.0024 0.0102 0.0236
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0326 0.0318
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0148 0.0849 0.1878
Echinococcus granulosus microtubule associated protein 2 0.0753 0.4484 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0214 0.1496
Schistosoma mansoni dishevelled 0.0009 0.0014 0.0013
Echinococcus granulosus GPCR family 2 0.0148 0.0849 0.1878
Onchocerca volvulus 0.0026 0.0113 0.026
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.016 0.0158
Echinococcus multilocularis RUN 0.0023 0.0095 0.0087
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.0012 0.0009
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0084 0.0076
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0113 0.0234
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0098 0.0247
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.016 0.1003
Echinococcus multilocularis dna repair and recombination protein rad54 0.0024 0.0102 0.0094
Schistosoma mansoni hypothetical protein 0.0015 0.005 0.0093
Onchocerca volvulus Huntingtin homolog 0.0141 0.0807 0.2081
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0084 0.017
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0113 0.0234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0084 0.019
Brugia malayi hypothetical protein 0.001 0.0018 0.0015
Schistosoma mansoni glutaminase 0.028 0.1643 0.3653
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.016 0.034
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.114 0.2976
Brugia malayi glutaminase DH11.1 0.028 0.1643 0.4281
Brugia malayi Doublecortin family protein 0.0023 0.0095 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0198 0.115 1
Schistosoma mansoni smad 0.0009 0.0012 0.0009
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0084 0.0076
Schistosoma mansoni importin beta-1 0.0029 0.013 0.0273
Brugia malayi hypothetical protein 0.004 0.0197 0.0485
Brugia malayi nuclear receptor RXR 0.0011 0.0025 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0025 0.0034
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0024 0.0102 0.021
Brugia malayi Nuclear hormone receptor E75 0.001 0.0018 0.0015
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0014 0.0006
Brugia malayi DIX domain containing protein 0.0009 0.0014 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Echinococcus granulosus Smad4 0.0009 0.0012 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0084 0.017
Onchocerca volvulus 0.001 0.0018 0.001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0084 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0084 0.019
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0534 0.1369
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0084 0.017
Schistosoma mansoni hypothetical protein 0.0106 0.0594 0.131
Echinococcus multilocularis serotonin transporter 0.0151 0.0867 0.086
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0643 0.3822 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0084 0.017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0084 0.019
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0095 0.0195
Schistosoma mansoni dep domain containing protein 0.0009 0.0014 0.0013
Brugia malayi Inositol-1 0.0043 0.0214 0.0531
Loa Loa (eye worm) hypothetical protein 0.0028 0.0124 0.0294
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0014 0.0005
Leishmania major hypothetical protein, conserved 0.0198 0.115 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.016 1
Echinococcus granulosus SPRY domain containing protein 0.0024 0.0102 0.021
Echinococcus granulosus zinc finger protein 0.0021 0.0087 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0084 0.019
Schistosoma mansoni nuclear receptor 0.001 0.0018 0.0022
Plasmodium falciparum flap endonuclease 1 0.0028 0.013 0.5298
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0084 0.019
Schistosoma mansoni hypothetical protein 0.0148 0.0849 0.1878
Schistosoma mansoni nuclear receptor 0.001 0.0018 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.012 0.1048
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0464 0.275 0.7186
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0026 0.0113 0.0105
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.1067
Loa Loa (eye worm) glutaminase 2 0.028 0.1643 0.4281
Loa Loa (eye worm) histone methyltransferase 0.001 0.002 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Echinococcus granulosus snurportin 1 0.0305 0.1792 0.3986
Echinococcus multilocularis dna repair and recombination protein rad54 0.0024 0.0102 0.0094
Schistosoma mansoni nuclear hormone receptor 0.001 0.0018 0.0022
Treponema pallidum sodium- and chloride- dependent transporter 0.0151 0.0867 0.4817
Echinococcus multilocularis 0.0024 0.0102 0.0094
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0034
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0018 0.0015
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0214 0.0206
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0018 0.0015
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0534 0.1369
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.016 0.1393
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0643 0.3822 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0084 0.0076
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0018 0.0015
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0014 0.0013
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0197 0.0421
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.114 0.2976
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0084 0.017
Schistosoma mansoni inositol monophosphatase 0.0043 0.0214 0.0461
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.038 0.0832
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0014 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0084 0.017
Brugia malayi hypothetical protein 0.0018 0.0065 0.014
Onchocerca volvulus Glucosylceramidase homolog 0.0187 0.108 0.2798
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0098 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0084 0.019
Loa Loa (eye worm) hypothetical protein 0.032 0.1881 0.4906
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0124 0.1079
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0065 0.0126
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0084 0.019
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0349 0.3615
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0025 0.0017
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0026 0.0113 0.0105
Echinococcus multilocularis zinc finger protein 0.0021 0.0087 0.0079
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.016 0.1576
Brugia malayi PHD-finger family protein 0.0027 0.0118 0.0279
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0025 0.0038
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0795 0.2687
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0024 0.0102 0.021
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0104 0.0096
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.013 0.0725
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0124 0.0676
Entamoeba histolytica DNA repair protein, putative 0.0024 0.0102 0.001
Echinococcus multilocularis snurportin 1 0.0305 0.1792 0.1786
Plasmodium vivax importin-beta 2, putative 0.0029 0.013 0.5427
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0025 0.0034
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0018 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0018 0.001
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0018 0.0022
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0084 0.017
Onchocerca volvulus 0.0023 0.0095 0.0213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0018 0.0015
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0214 0.0552
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0084 0.017
Schistosoma mansoni lipoxygenase 0.0136 0.0775 0.1714
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0214 0.1496
Brugia malayi Bromodomain containing protein 0.0038 0.0187 0.0459
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0025 0.0038
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.016 0.1393
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0136 0.0775 0.0768
Trypanosoma brucei DNA repair and recombination protein RAD54, putative 0.0024 0.0102 0.0886
Brugia malayi latrophilin 2 splice variant baaae 0.032 0.1881 0.4906
Schistosoma mansoni zinc finger protein 0.0015 0.005 0.0093
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0034
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0065 0.0126
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.1792 0.4672
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0157 0.0382
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0084 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0187 0.0267
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0148 0.0849 0.2196
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0084 0.0076
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0113 0.0105
Giardia lamblia Kinase, CMGC MAPK 0.0164 0.0942 0.2063
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0151 0.0867 0.2245
Entamoeba histolytica hypothetical protein 0.004 0.0197 0.0249
Entamoeba histolytica hypothetical protein 0.0027 0.012 0.0057
Entamoeba histolytica hypothetical protein 0.004 0.0197 0.0249
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Schistosoma mansoni dishevelled 0.0009 0.0014 0.0013
Schistosoma mansoni survival motor neuron protein 0.0106 0.0594 0.131
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0942 0.2457
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0102 0.0236
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0198 0.115 0.3001
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Plasmodium vivax amine transporter, putative 0.0026 0.0113 0.2737
Brugia malayi hypothetical protein 0.0028 0.0124 0.0294
Loa Loa (eye worm) hypothetical protein 0.0148 0.0849 0.2196
Brugia malayi isocitrate dehydrogenase 0.0034 0.016 0.0389
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0012 0.0009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0164 0.0942 0.0935
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.0265
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0018 0.0022
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.1671 1
Brugia malayi ecdysone receptor 0.001 0.0018 0.0015
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0164 0.0942 0.8111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0084 0.019
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0198 0.115 0.3001
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0124 0.4455
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.016 0.0389
Trichomonas vaginalis glutaminase, putative 0.028 0.1643 0.4293
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0024 0.0102 0.0474
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0014 0.0013
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0643 0.3822 0.9385
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0084 0.0076
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0084 0.017
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0445 0.2631 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0084 0.017
Onchocerca volvulus 0.0026 0.0113 0.026
Brugia malayi MH2 domain containing protein 0.013 0.0741 0.1915
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.013 0.0309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0124 0.4455
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.013 0.033
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0014 0.0013
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0082 0.0183
Echinococcus multilocularis flap endonuclease 1 0.0028 0.013 0.0122
Echinococcus multilocularis SPRY domain containing protein 0.0024 0.0102 0.0094
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0018 0.0015
Toxoplasma gondii hypothetical protein 0.0026 0.0113 0.1067
Brugia malayi hypothetical protein 0.0023 0.0095 0.0218
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0164 0.0942 0.8111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0095 0.0087
Schistosoma mansoni sodium-dependent amino acid transporter 0.0026 0.0113 0.0234
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0643 0.3822 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.1067
Echinococcus granulosus dna repair and recombination protein rad54 0.0024 0.0102 0.021
Schistosoma mansoni flap endonuclease-1 0.0026 0.0113 0.0235
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.1667 0.4344
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.006 0.0117
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0014 0.0006
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0014 0.0013
Onchocerca volvulus 0.0023 0.0095 0.0213
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0173 0.0165
Echinococcus multilocularis dna repair and recombination protein rad54 0.0024 0.0102 0.0094
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Echinococcus multilocularis GPCR, family 2 0.0148 0.0849 0.0841
Loa Loa (eye worm) hypothetical protein 0.0024 0.0102 0.0236
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0084 0.017
Echinococcus granulosus SPRY domain containing protein 0.0024 0.0102 0.021
Brugia malayi hypothetical protein 0.0009 0.0014 0.0005
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0014 0.0013
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0096 0.0534 0.137
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0113 0.0234
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0084 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Echinococcus granulosus mitogen activated protein kinase 0.0164 0.0942 0.2087
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.016 0.0152
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0214 0.1496
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.016 0.1576
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0124 0.1187
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0468 0.2771 0.7242
Brugia malayi Flap endonuclease-1 0.0028 0.013 0.0309
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.013 0.5298
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0214 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0214 0.0253
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0197 0.0189
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Brugia malayi nuclear hormone receptor 0.001 0.0018 0.0015
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.013 0.1134
Loa Loa (eye worm) hypothetical protein 0.0024 0.0102 0.0236
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0095 0.0195
Echinococcus multilocularis importin subunit beta 1 0.0029 0.013 0.0122
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0148 0.0849 0.0841
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0468 0.2771 0.7242
Entamoeba histolytica hypothetical protein 0.004 0.0197 0.0249
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0084 0.019
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0104 0.0215
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Brugia malayi nuclear receptor RXR 0.001 0.0018 0.0015
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0113 0.0234
Brugia malayi ecdysteroid receptor 0.0021 0.0084 0.019
Brugia malayi CXXC zinc finger family protein 0.0033 0.0157 0.0382
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0534 0.1175
Brugia malayi conserved hypotetical protein 0.001 0.0018 0.0015
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.012 0.1149
Brugia malayi hypothetical protein 0.001 0.0018 0.0015
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0014 0.0006
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0643 0.3822 0.9385
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0018 0.0022
Echinococcus granulosus importin subunit beta 1 0.0029 0.013 0.0273
Loa Loa (eye worm) hypothetical protein 0.0141 0.0807 0.2085
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0084 0.017
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0018 0.0022
Brugia malayi nuclear receptor NHR-88 0.001 0.0018 0.0015
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0187 0.1082 0.2804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0534 0.0526
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0018 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0942 0.2087
Loa Loa (eye worm) hypothetical protein 0.0151 0.0867 0.2245
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0124 0.0676
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0741 0.1915
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0084 0.0076
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0741 0.1915
Echinococcus multilocularis smad 0.0009 0.0012 0.0004
Echinococcus multilocularis survival motor neuron protein 1 0.0519 0.3075 0.3069
Trypanosoma brucei ISWI complex protein 0.0015 0.005 0.0433
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0084 0.0076
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1671 0.3964
Schistosoma mansoni hypothetical protein 0.004 0.0197 0.0421
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0942 0.2457
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.002 0.0027
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0014 0.0013
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.0012 0.0004
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0643 0.3822 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0113 0.0234
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.1067
Loa Loa (eye worm) glutaminase 0.028 0.1643 0.4281
Onchocerca volvulus 0.0151 0.0867 0.2241
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0084 0.017
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.006 0.0117
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0187 0.0993
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Entamoeba histolytica hypothetical protein 0.0194 0.1127 0.2594
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0095 0.0218
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0214 0.0293
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0018 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0102 0.0236
Plasmodium falciparum DNA repair and recombination protein RAD54, putative 0.0024 0.0102 0.105
Brugia malayi Nuclear hormone receptor E75 0.001 0.0018 0.0015
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0198 0.115 1
Brugia malayi hypothetical protein 0.0519 0.3075 0.8039
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0643 0.3822 1
Giardia lamblia DNA repair protein RAD52 0.0683 0.4066 1
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0084 0.017
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Schistosoma mansoni hypothetical protein 0.0148 0.0849 0.1878
Schistosoma mansoni hypothetical protein 0.0471 0.279 0.6215
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.016 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0084 0.017
Schistosoma mansoni smad1 5 8 and 0.0009 0.0012 0.0009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0173 0.0368
Brugia malayi Calcitonin receptor-like protein seb-1 0.0468 0.2771 0.7242
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0942 0.2457
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0136 0.0775 0.1714
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0084 0.019
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.013 0.1246
Mycobacterium ulcerans glutaminase 0.028 0.1643 0.4113
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.1667 0.4344
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0084 0.017
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Echinococcus multilocularis SPRY domain containing protein 0.0024 0.0102 0.0094
Loa Loa (eye worm) DR-78 0.001 0.0018 0.0015
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0014 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.1667 0.4356
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.1667 0.4356
Schistosoma mansoni cpg binding protein 0.0037 0.018 0.0385
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0065 0.0126
Schistosoma mansoni bromodomain containing protein 0.0065 0.0347 0.0757
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.013 0.0725
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0026 0.0113 0.0234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.046
Schistosoma mansoni smad1 5 8 and 0.0009 0.0012 0.0009
Onchocerca volvulus 0.0643 0.3822 1
Echinococcus multilocularis cpg binding protein 0.0037 0.018 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Loa Loa (eye worm) hypothetical protein 0.004 0.0201 0.0497
Schistosoma mansoni cpg binding protein 0.0033 0.0157 0.0334
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0026 0.0113 0.0234
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Schistosoma mansoni zinc finger protein 0.001 0.0018 0.0022
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.012 0.3904
Brugia malayi Isocitrate dehydrogenase 0.0034 0.016 0.0389
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.006 0.0052
Echinococcus granulosus mitogen activated protein kinase 3 0.0164 0.0942 0.2087
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.012 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0084 0.019
Brugia malayi Latrophilin receptor protein 2 0.0148 0.0849 0.2196
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.016 0.1003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0005
Brugia malayi recombination factor GdRad54 0.0024 0.0102 0.0236
Brugia malayi hypothetical protein 0.0141 0.0807 0.2085
Plasmodium falciparum transporter, putative 0.0026 0.0113 0.2737
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0084 0.019
Loa Loa (eye worm) serotonin transporter b 0.0151 0.0867 0.2245
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0148 0.0849 0.1878
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0084 0.019
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0311
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0018 0.0022
Echinococcus granulosus cpg binding protein 0.0037 0.018 0.0385
Loa Loa (eye worm) solute carrier family 6 member 4 0.0151 0.0867 0.2245
Loa Loa (eye worm) latrophilin receptor protein 2 0.0148 0.0849 0.2196
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0122 0.0254
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.012 0.1149
Schistosoma mansoni polycystin 1-related 0.0023 0.0095 0.0195
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0018 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0198 0.115 1
Schistosoma mansoni cpg binding protein 0.0037 0.018 0.0385
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.016 0.0152
Schistosoma mansoni rab6-interacting 0.0023 0.0095 0.0195
Loa Loa (eye worm) hypothetical protein 0.0468 0.2771 0.7242
Loa Loa (eye worm) hypothetical protein 0.0519 0.3075 0.8039
Echinococcus multilocularis mitogen activated protein kinase 0.0164 0.0942 0.0935
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.016 0.0152
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0084 0.017
Loa Loa (eye worm) norepinephrine transporter 0.0151 0.0867 0.2245
Brugia malayi hypothetical protein 0.0026 0.0113 0.0265
Schistosoma mansoni hypothetical protein 0.002 0.0082 0.0164
Entamoeba histolytica DNA repair protein, putative 0.0024 0.0102 0.001
Brugia malayi nuclear hormone receptor 0.0021 0.0084 0.019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0065 0.0057
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0214 0.0552
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.013 0.1255
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.0265
Loa Loa (eye worm) hypothetical protein 0.0141 0.0807 0.2085
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.016 0.0152
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0084 0.019
Echinococcus multilocularis Smad4 0.0009 0.0012 0.0004
Schistosoma mansoni hypothetical protein 0.0012 0.0033 0.0055
Onchocerca volvulus Huntingtin homolog 0.0141 0.0807 0.2081
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.012 0.0643
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.019
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0214 0.0552
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0098 0.0438
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0026 0.0113 0.0105
Echinococcus granulosus smad 0.0009 0.0012 0.0009
Onchocerca volvulus 0.001 0.0018 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0197 0.0421
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0005
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0084 0.0076
Onchocerca volvulus 0.0026 0.0113 0.026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0065 0.0138
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0015
Brugia malayi steroid hormone receptor 0.0021 0.0084 0.019
Schistosoma mansoni zinc finger protein 0.0021 0.0087 0.0176
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0113 0.2737
Echinococcus granulosus SPRY domain containing protein 0.0024 0.0102 0.021
Leishmania major importin beta-1 subunit, putative 0.0023 0.0098 0.0438
Echinococcus granulosus dnaJ subfamily B 0.0471 0.279 0.6215
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0594 0.1528
Echinococcus granulosus serotonin transporter 0.0151 0.0867 0.192
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0095 0.0087
Onchocerca volvulus 0.0021 0.0084 0.0185
Loa Loa (eye worm) hypothetical protein 0.0026 0.0113 0.0265
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0683 0.4066 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0098 0.0247
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0018 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1671 0.4367
Echinococcus granulosus survival motor neuron protein 1 0.0519 0.3075 0.6853
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.108 0.2817
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0084 0.017
Schistosoma mansoni sodium/chloride dependent transporter 0.0151 0.0867 0.192
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.013 0.1127
Entamoeba histolytica Flap nuclease, putative 0.0028 0.013 0.008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0164 0.0942 0.8111
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0113 0.0265
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0084 0.019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0084 0.019
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0187 0.1082 0.2807
Loa Loa (eye worm) hypothetical protein 0.0151 0.0867 0.2245
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0014 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0102 0.0236

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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