Detailed information for compound 172616

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 410.595 | Formula: C11H12ClIN4O3
  • H donors: 3 H acceptors: 4 LogP: 0.36 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCC1OC(C(C1O)O)n1cc(c2c1ncnc2Cl)I
  • InChi: 1S/C11H12ClIN4O3/c12-9-6-4(13)2-17(10(6)16-3-15-9)11-8(19)7(18)5(1-14)20-11/h2-3,5,7-8,11,18-19H,1,14H2
  • InChiKey: QATUTGXCWAHTTP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus phd:f box containing protein 0.0019 0.0016 0.0018
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0021 0.0023
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0044 0.0182 0.0201
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0266 0.0108
Trichomonas vaginalis tubulin alpha chain, putative 0.0017 0.0001 0.0001
Echinococcus granulosus tubulin gamma 1 chain 0.0029 0.0085 0.0094
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0044 0.0182 0.1002
Echinococcus multilocularis Tubulin beta 2C chain 0.0046 0.0194 0.0214
Toxoplasma gondii alpha tubulin TUBA1 0.0046 0.0192 0.0578
Onchocerca volvulus 0.0093 0.0506 0.0816
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Echinococcus granulosus tubulin alpha 1C chain 0.0046 0.0192 0.0212
Giardia lamblia Thioredoxin reductase 0.0044 0.0182 0.027
Loa Loa (eye worm) tubulin beta-4 chain 0.0046 0.0194 0.0211
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.053 0.1736
Echinococcus multilocularis tubulin alpha 3 chain 0.0046 0.0192 0.0212
Echinococcus granulosus tubulin alpha chain 0.0046 0.0192 0.0212
Schistosoma mansoni tubulin subunit beta 0.0046 0.0194 0.0194
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0601 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Toxoplasma gondii beta-1 tubulin, putative 0.0046 0.0194 0.0585
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0802 0.2623
Leishmania major phosphopantetheinyl transferase-like protein 0.0047 0.02 0.0605
Brugia malayi 6-phosphofructokinase 0.0108 0.0601 0.0655
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0021 0.0023
Plasmodium falciparum glutathione reductase 0.0166 0.0988 0.3196
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0046 0.0194 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Echinococcus multilocularis expressed protein 0.0383 0.2417 0.2664
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0361 0.0361
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0192 0.031
Echinococcus granulosus axis inhibition protein axin 0.002 0.0021 0.0023
Echinococcus multilocularis transcription factor btf3 0.0035 0.0125 0.0137
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0083 0.0221
Trypanosoma cruzi DNA polymerase eta, putative 0.0183 0.1099 0.3598
Trypanosoma brucei epsilon tubulin 0.0029 0.0085 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0553 0.0892
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0166 0.0988 0.3231
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0166 0.0988 0.1089
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0044 0.0182 0.1002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Echinococcus granulosus L aminoadipate semialdehyde 0.0166 0.099 0.1091
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0021 0.0023
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0016 0.0018
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0098 0.0538 0.176
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0279 0.0308
Giardia lamblia PHD finger protein 15 0.0059 0.0279 0.0534
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0266 0.0822
Schistosoma mansoni tubulin subunit beta 0.0046 0.0194 0.0194
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0166 0.0988 0.3196
Echinococcus granulosus tubulin alpha 3 chain 0.0046 0.0192 0.0212
Echinococcus granulosus tubulin alpha 3 chain 0.0046 0.0192 0.0212
Echinococcus multilocularis lamin dm0 0.0027 0.0067 0.0074
Plasmodium falciparum glutathione reductase 0.0479 0.3056 1
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0047 0.02 0.0246
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Toxoplasma gondii selenide, water dikinase 0.0044 0.0182 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Giardia lamblia Beta tubulin 0.0046 0.0194 0.0302
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0083 0.022
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0125 0.0356
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0047 0.02 0.0605
Plasmodium falciparum alpha tubulin 2 0.0046 0.0192 0.0578
Echinococcus granulosus Tubulin alpha 1 chain 0.0046 0.0192 0.0212
Echinococcus granulosus axis inhibition protein axin 0.002 0.0021 0.0023
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0125 0.0405
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0016 0.0016
Schistosoma mansoni axis inhibition protein axin 0.002 0.0021 0.0021
Entamoeba histolytica tubulin family protein 0.0046 0.0194 0.0517
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0166 0.0988 0.3196
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0125 0.0136
Trypanosoma brucei beta tubulin 0.0046 0.0194 0.0632
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0067 0.0073
Plasmodium vivax tubulin alpha chain, putative 0.0046 0.0192 0.0578
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0195 0.0215
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0021 0.0023
Toxoplasma gondii beta tubulin 0.0046 0.0194 0.0585
Leishmania major gamma-tubulin 0.0029 0.0085 0.0226
Echinococcus granulosus tubulin alpha 0.0029 0.0085 0.0094
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0016 0.0018
Plasmodium falciparum thioredoxin reductase 0.0166 0.0988 0.3196
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0601 0.097
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3196
Loa Loa (eye worm) tubulin gamma chain 0.0029 0.0085 0.0093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Brugia malayi PHD-finger family protein 0.0019 0.0018 0.002
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0021 0.0023
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0131 0.0758 0.0826
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0044 0.0182 0.0594
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.0845 0.2728
Echinococcus multilocularis beta tubulin 0.0046 0.0194 0.0214
Onchocerca volvulus Alhambra homolog 0.0059 0.0279 0.045
Leishmania major NADH dehydrogenase, putative 0.0044 0.0182 0.0546
Schistosoma mansoni DNA polymerase IV / kappa 0.0041 0.016 0.016
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0021 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0131 0.0758 0.0836
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0131 0.0758 0.0758
Echinococcus granulosus lamin dm0 0.0027 0.0067 0.0074
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Loa Loa (eye worm) tubulin alpha-3 chain 0.0029 0.0082 0.009
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.012 0.0686 0.0757
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0044 0.0182 0.0546
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Onchocerca volvulus 0.0166 0.099 0.1595
Trypanosoma brucei unspecified product 0.0091 0.0489 0.1599
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0044 0.0182 0.0198
Echinococcus granulosus Tubulin beta 2C chain 0.0046 0.0194 0.0214
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0044 0.0182 0.0546
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0601 0.2728
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0601 0.0542
Plasmodium vivax tubulin alpha chain, putative 0.0046 0.0192 0.0578
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0204 0.0617
Loa Loa (eye worm) tubulin alpha 2 0.0033 0.0108 0.0117
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0044 0.0182 0.0201
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0241 0.0262
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0044 0.0182 0.0486
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1093 0.711 0.8958
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0083 0.022
Giardia lamblia Kinase, PLK 0.0097 0.053 0.1219
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0001 0.0001
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0044 0.0182 0.0201
Trichomonas vaginalis tubulin alpha chain, putative 0.0017 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0601 0.1968
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.016 0.0525
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0601 0.0542
Trypanosoma cruzi trypanothione reductase, putative 0.0166 0.0988 0.3233
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0044 0.0182 0.0198
Echinococcus multilocularis glutamate synthase 0.0044 0.0182 0.0201
Echinococcus granulosus Tubulin beta 2C chain 0.0046 0.0194 0.0214
Schistosoma mansoni kinase 0.0049 0.0216 0.0216
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0125 0.0408
Echinococcus granulosus alpha tubulin 0.0046 0.0192 0.0212
Trypanosoma brucei polo-like protein kinase 0.0097 0.053 0.1734
Brugia malayi Pre-SET motif family protein 0.012 0.0686 0.0748
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.0845 0.2767
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0034
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0218 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0182 0.0596
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0175 0.0572
Trichomonas vaginalis tubulin alpha chain, putative 0.0029 0.0085 0.0137
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0018 0.0005
Echinococcus granulosus thioredoxin glutathione reductase 0.0482 0.3073 0.3387
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0016 0.0018
Trichomonas vaginalis tubulin epsilon chain, putative 0.0046 0.0194 0.0313
Echinococcus multilocularis dna polymerase kappa 0.0158 0.0934 0.103
Giardia lamblia Beta tubulin 0.0046 0.0194 0.0302
Entamoeba histolytica tubulin alpha chain, putative 0.0046 0.0192 0.0512
Onchocerca volvulus 0.0027 0.0067 0.0109
Mycobacterium tuberculosis Probable oxidoreductase 0.1215 0.7915 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0044 0.0182 0.0486
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0016 0.0016
Brugia malayi tubulin alpha-2 chain 0.0046 0.0192 0.0209
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Trypanosoma brucei NADH dehydrogenase 0.0044 0.0182 0.0594
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0044 0.0182 0.0135
Echinococcus granulosus peroxisome assembly protein 26 0.0046 0.0192 0.0212
Echinococcus granulosus tubulin subunit beta 0.0046 0.0194 0.0214
Trichomonas vaginalis tubulin gamma chain, putative 0.0029 0.0085 0.0137
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0266 0.0293
Trichomonas vaginalis rotamase, putative 0.01 0.0553 0.0892
Brugia malayi glutamate synthase 0.0044 0.0182 0.0198
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0021 0.0021
Schistosoma mansoni sulfide quinone reductase 0.0044 0.0182 0.0182
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0058 0.0187
Loa Loa (eye worm) hypothetical protein 0.0067 0.0336 0.0366
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0125 0.0356
Trypanosoma brucei DNA polymerase IV, putative 0.0151 0.0891 0.2913
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0021 0.0021
Brugia malayi Tubulin alpha-2 chain 0.0046 0.0192 0.0209
Echinococcus granulosus geminin 0.0339 0.213 0.2347
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.0431 0.0475
Schistosoma mansoni jumonji domain containing protein 0.0153 0.09 0.09
Schistosoma mansoni regulator of G protein signaling 0.002 0.0021 0.0021
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0044 0.0182 0.0135
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Brugia malayi beta-tubulin, identical 0.0046 0.0194 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0208 0.0335
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0479 0.3056 0.3716
Trypanosoma brucei alpha tubulin 0.0046 0.0192 0.0626
Trypanosoma cruzi epsilon tubulin, putative 0.0029 0.0085 0.0279
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0195 0.0195
Brugia malayi intermediate filament protein 0.0027 0.0067 0.0073
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0092 0.0501 0.1596
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0372 0.041
Brugia malayi beta-NAC-like protein 0.0035 0.0125 0.0136
Echinococcus granulosus tubulin alpha chain 0.0046 0.0192 0.0212
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.003 0.0093 0.03
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.1468 0.1599
Trypanosoma brucei adenosine kinase, putative 0.0105 0.0585 0.1913
Echinococcus multilocularis Tubulin beta 2C chain 0.0046 0.0194 0.0214
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0018
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0018 0.0056
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0044 0.0182 0.0546
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Echinococcus multilocularis dna polymerase eta 0.0183 0.1099 0.1212
Schistosoma mansoni lamin 0.0027 0.0067 0.0067
Schistosoma mansoni transcription factor btf3 0.0035 0.0125 0.0125
Plasmodium vivax tubulin beta chain, putative 0.0046 0.0194 0.0585
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.0845 0.2765
Brugia malayi hypothetical protein 0.002 0.0021 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Schistosoma mansoni regulator of G protein signaling 0.002 0.0021 0.0021
Schistosoma mansoni regulator of G protein signaling 0.002 0.0021 0.0021
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0585 0.3752 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0016 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0533 0.1742
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0361 0.0393
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0067 0.0073
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0044 0.0182 0.0546
Echinococcus multilocularis tubulin alpha chain 0.0046 0.0192 0.0212
Echinococcus granulosus dna polymerase kappa 0.0158 0.0934 0.103
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0286 0.1777 0.2063
Echinococcus multilocularis hypothetical protein 0.0046 0.0192 0.0212
Trypanosoma brucei epsilon tubulin 0.0029 0.0085 0.0276
Plasmodium falciparum DNA repair protein REV1, putative 0.0041 0.016 0.0474
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0166 0.0988 0.3231
Echinococcus multilocularis geminin 0.0339 0.213 0.2347
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0083 0.0134
Echinococcus granulosus expressed protein 0.0383 0.2417 0.2664
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0601 0.0663
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0192 0.031
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0021 0.0023
Trypanosoma brucei DNA polymerase IV, putative 0.0158 0.0934 0.3056
Plasmodium vivax DNA repair protein REV1, putative 0.0041 0.016 0.0474
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.005 0.0218 0.0238
Schistosoma mansoni tubulin subunit beta 0.0046 0.0194 0.0194
Echinococcus multilocularis lamin 0.0027 0.0067 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3233
Plasmodium vivax tubulin epsilon chain, putative 0.0029 0.0085 0.0226
Trypanosoma cruzi DNA polymerase kappa, putative 0.0158 0.0934 0.3058
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0044 0.0182 0.0198
Brugia malayi Tubulin beta-1 chain 0.0046 0.0194 0.0211
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.1908 0.6243
Brugia malayi AF-10 protein 0.0019 0.0018 0.002
Schistosoma mansoni lamin 0.0027 0.0067 0.0067
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0131 0.0758 0.0836
Trichomonas vaginalis tubulin gamma chain, putative 0.0029 0.0085 0.0137
Schistosoma mansoni tubulin subunit alpha 0.0046 0.0192 0.0192
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0044 0.0182 0.1002
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0083 0.0134
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0044 0.0182 0.0135
Plasmodium falciparum phd finger protein, putative 0.0059 0.0279 0.0864
Brugia malayi jmjC domain containing protein 0.0019 0.0016 0.0018
Brugia malayi MH2 domain containing protein 0.0239 0.1468 0.1599
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0601 0.1413
Brugia malayi 6-phosphofructokinase 0.0108 0.0601 0.0655
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0029 0.0085 0.0226
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0083 0.0134
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.016 0.0522
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0047 0.02 0.0319
Schistosoma mansoni disulfide oxidoreductase 0.0044 0.0182 0.0182
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0046 0.0192 0.031
Trypanosoma cruzi epsilon tubulin, putative 0.0029 0.0085 0.0279
Echinococcus multilocularis microtubule associated protein 2 0.138 0.9008 0.9928
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0023 0.0025
Plasmodium falciparum ferrodoxin reductase-like protein 0.0044 0.0182 0.0546
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3196
Schistosoma mansoni rotamase 0.01 0.0553 0.0553
Trypanosoma cruzi NADH dehydrogenase, putative 0.0044 0.0182 0.0596
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0044 0.0182 0.0135
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.016 0.0522
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.016 0.0525
Schistosoma mansoni tubulin subunit gamma 0.0029 0.0085 0.0085
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0692 0.0754
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0279 0.0864
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0021 0.0023
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0021 0.0021
Giardia lamblia Glutamate synthase 0.0044 0.0182 0.027
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0044 0.0182 0.0486
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0286 0.1777 1
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0192 0.031
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1215 0.7915 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0018 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0195 0.0215
Schistosoma mansoni alpha tubulin 0.0046 0.0192 0.0192
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0083 0.0134
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0166 0.0988 0.3196
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0601 0.1603
Loa Loa (eye worm) beta-tubulin 0.0046 0.0194 0.0211
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Loa Loa (eye worm) hypothetical protein 0.0046 0.0192 0.0209
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Echinococcus multilocularis tubulin alpha chain 0.0046 0.0192 0.0212
Loa Loa (eye worm) RGS-3 protein 0.002 0.0021 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0182 0.0294
Loa Loa (eye worm) alpha-tubulin 0.0046 0.0192 0.0209
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0166 0.0988 0.3231
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0182 0.0596
Schistosoma mansoni tubulin subunit beta 0.0046 0.0194 0.0194
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0195 0.0195
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0018 0.0056
Onchocerca volvulus 0.0044 0.0182 0.0294
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0044 0.0182 0.0546
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0047 0.02 0.0605
Entamoeba histolytica hypothetical protein 0.002 0.0021 0.0056
Leishmania major adenosine kinase, putative 0.0105 0.0585 0.1872
Giardia lamblia Beta tubulin 0.0046 0.0194 0.0302
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0166 0.0988 0.1042
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0175 0.0569
Echinococcus multilocularis peroxisome assembly protein 26 0.0046 0.0192 0.0212
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0585 0.3752 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.0336 0.1098
Toxoplasma gondii thioredoxin reductase 0.0479 0.3056 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0372 0.041
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0266 0.0293
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.01 0.0553 0.0603
Brugia malayi phosphofructokinase 0.0108 0.0601 0.0655
Schistosoma mansoni tyrosine kinase 0.139 0.9073 0.9073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Trypanosoma brucei DNA damage repair protein, putative 0.0041 0.016 0.0522
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.0336 0.1098
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0021 0.0023
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0016 0.0018
Schistosoma mansoni hypothetical protein 0.0339 0.213 0.213
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Trichomonas vaginalis tubulin epsilon chain, putative 0.0046 0.0192 0.031
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0182 0.0294
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0044 0.0182 0.0546
Schistosoma mansoni hypothetical protein 0.0059 0.0279 0.0279
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0166 0.0988 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0023
Trichomonas vaginalis tubulin, putative 0.0017 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0125 0.0201
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0047 0.02 0.1294
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0601 0.1603
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0125 0.0332
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0016 0.0053
Echinococcus granulosus jumonji domain containing protein 0.0082 0.0431 0.0475
Trypanosoma brucei epsilon tubulin 0.0029 0.0085 0.0276
Echinococcus multilocularis tubulin alpha 3 chain 0.0046 0.0192 0.0212
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0044 0.0182 0.0201
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3233
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.003 0.0093 0.0303
Echinococcus multilocularis Tubulin beta 2C chain 0.0046 0.0194 0.0214
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0058 0.0137
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0016 0.0016
Leishmania major trypanothione reductase 0.0479 0.3056 1
Trichomonas vaginalis glutamate synthase, putative 0.0044 0.0182 0.0294
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0266 0.0654
Trypanosoma cruzi DNA polymerase kappa, putative 0.0158 0.0934 0.3058
Mycobacterium ulcerans DNA polymerase IV 0.0158 0.0934 0.4787
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0182 0.0294
Echinococcus granulosus tubulin beta 1 chain 0.0046 0.0194 0.0214
Echinococcus multilocularis L aminoadipate semialdehyde 0.0166 0.099 0.1091
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0601 0.0655
Treponema pallidum thioredoxin reductase (trxB) 0.0044 0.0182 0.027
Toxoplasma gondii kinase, pfkB family protein 0.0105 0.0585 0.1872
Giardia lamblia DINP protein human, muc B family 0.0138 0.0802 0.196
Brugia malayi glutathione reductase 0.0479 0.3056 0.3328
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0044 0.0182 0.027
Leishmania major hypothetical protein, conserved 0.0044 0.0182 0.0546
Schistosoma mansoni adenosine kinase 0.0105 0.0585 0.0585
Trypanosoma brucei beta tubulin 0.0046 0.0194 0.0632
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.016 0.0474
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0021 0.0023
Mycobacterium ulcerans DNA polymerase IV 0.0158 0.0934 0.4787
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Mycobacterium ulcerans dehydrogenase 0.0044 0.0182 0.0135
Trichomonas vaginalis glutathione reductase, putative 0.0166 0.0988 0.1593
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0601 0.097
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0182 0.0594
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.053 0.1414
Loa Loa (eye worm) alpha-tubulin 0.0046 0.0192 0.0209
Trypanosoma brucei DNA polymerase IV, putative 0.0158 0.0934 0.3056
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.003 0.0093 0.0303
Echinococcus multilocularis musashi 0.0027 0.0067 0.0074
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.053 0.1692
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0023 0.0023
Plasmodium falciparum tubulin gamma chain 0.0029 0.0085 0.0226
Schistosoma mansoni axis inhibition protein axin 0.002 0.0021 0.0021
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0044 0.0182 0.0596
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0166 0.0988 0.3196
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.012 0.0686 0.0757
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0601 0.1925
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0195 0.0215
Mycobacterium ulcerans monoxygenase 0.0044 0.0182 0.0135
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.003 0.0093 0.0251
Trypanosoma brucei alpha tubulin 0.0046 0.0192 0.0626
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0083 0.0134
Plasmodium falciparum alpha tubulin 1 0.0046 0.0192 0.0578
Echinococcus multilocularis tubulin alpha 0.0029 0.0085 0.0094
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0047 0.02 0.1202
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0044 0.0182 0.0486
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.012 0.0686 0.0748
Loa Loa (eye worm) tubulin beta-1 chain 0.0046 0.0194 0.0211
Echinococcus multilocularis tubulin alpha 1C chain 0.0046 0.0192 0.0212
Echinococcus granulosus Tubulin beta 2C chain 0.0046 0.0194 0.0214
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0016 0.0018
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0044 0.0182 0.0201
Echinococcus granulosus Solute carrier family 22 5 0.1024 0.6656 0.7336
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.012 0.0686 0.2205
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0018
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0182 0.0596
Loa Loa (eye worm) programmed cell death 8 0.0044 0.0182 0.0198
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0098 0.0538 0.1433
Loa Loa (eye worm) tubulin beta chain 0.0046 0.0194 0.0211
Entamoeba histolytica disulphide oxidoreductase, putative 0.0044 0.0182 0.0486
Loa Loa (eye worm) tubulin alpha chain 0.0046 0.0192 0.0209
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.1468 0.1599
Echinococcus multilocularis Tubulin alpha 1 chain 0.0046 0.0192 0.0212
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Trypanosoma cruzi alpha tubulin, putative 0.0046 0.0192 0.0629
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0601 0.0655
Onchocerca volvulus 0.0956 0.6202 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0122 0.0697 0.0759
Echinococcus granulosus tubulin alpha chain 0.0046 0.0192 0.0212
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0195 0.0215
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0016 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0034
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0166 0.0988 0.3196
Trypanosoma cruzi adenosine kinase, putative 0.0105 0.0585 0.1915
Giardia lamblia Alpha-tubulin 0.0046 0.0192 0.0297
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.053 0.0578
Trichomonas vaginalis rotamase, putative 0.0098 0.0538 0.0867
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0175 0.0572
Trypanosoma cruzi tubulin gamma chain 0.0029 0.0085 0.0279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0686 0.0686
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0266 0.0266
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0138 0.0802 0.0802
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0021 0.0023
Leishmania major hypothetical protein, conserved 0.0044 0.0182 0.0546
Plasmodium vivax SET domain protein, putative 0.012 0.0686 0.2205
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0098 0.0538 0.176
Loa Loa (eye worm) tubulin alpha 2 0.0033 0.0108 0.0117
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0098 0.0538 0.1716
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0044 0.0182 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0125 0.0201
Toxoplasma gondii hypothetical protein 0.0049 0.0216 0.0658
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0067 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0023
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.0953 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0034
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0029 0.0082 0.0133
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0166 0.0988 0.5117
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0047 0.02 0.0023
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0058 0.0137
Trypanosoma brucei DNA polymerase eta, putative 0.0183 0.1099 0.3596
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0021 0.0034
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0122 0.0697 0.0759
Trypanosoma brucei DNA damage repair protein, putative 0.0041 0.016 0.0522
Leishmania major DNA polymerase eta, putative 0.0092 0.0501 0.1596
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0166 0.0988 0.3231
Entamoeba histolytica thioredoxin reductase, putative 0.0044 0.0182 0.0486
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0361 0.0361
Schistosoma mansoni tubulin subunit alpha 0.0046 0.0192 0.0192
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1215 0.7915 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.1099 0.1197
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0021 0.0023
Trichomonas vaginalis tubulin alpha chain, putative 0.0017 0.0001 0.0001
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0266 0.029
Echinococcus granulosus dna polymerase eta 0.0183 0.1099 0.1212
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0839 0.5435 0.592
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0166 0.0988 1
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0016 0.0018
Entamoeba histolytica hypothetical protein 0.002 0.0021 0.0056
Plasmodium vivax glutathione reductase, putative 0.0479 0.3056 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0166 0.099 0.1078
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0021 0.0023
Entamoeba histolytica hypothetical protein 0.0047 0.02 0.0533
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0601 0.1603
Trypanosoma brucei beta tubulin 0.0046 0.0194 0.0632
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0166 0.0988 0.3233
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0266 0.0654
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0021 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0533 0.1742
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3233
Echinococcus multilocularis Tubulin beta 2C chain 0.0046 0.0194 0.0214
Echinococcus granulosus histone lysine methyltransferase setb 0.012 0.0686 0.0757
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0158 0.0934 0.1507
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0166 0.099 0.099
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0083 0.022
Plasmodium vivax ferrodoxin reductase, putative 0.0044 0.0182 0.0546
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0044 0.0182 0.0135
Schistosoma mansoni terminal deoxycytidyl transferase 0.0131 0.0758 0.0758
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0195 0.0213
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0305 0.1908 0.6241
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Echinococcus granulosus tumor protein p63 0.0339 0.2127 0.2344
Onchocerca volvulus 0.0017 0.0001 0.0001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0138 0.0802 0.2585
Brugia malayi Tubulin beta chain 0.0017 0.0001 0.0001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0182 0.0294
Trypanosoma brucei hypothetical protein, conserved 0.0047 0.02 0.0652
Echinococcus multilocularis tubulin epsilon chain 0.0029 0.0085 0.0094
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0016 0.0016
Echinococcus granulosus tubulin alpha 1C chain 0.0046 0.0192 0.0212
Mycobacterium tuberculosis Conserved hypothetical protein 0.0131 0.0758 0.0745
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0044 0.0182 0.0294
Entamoeba histolytica tubulin family protein 0.0046 0.0194 0.0517
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0044 0.0182 0.0135
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0017 0.0001 0.0001
Echinococcus granulosus Tubulin beta 2C chain 0.0046 0.0194 0.0214
Toxoplasma gondii peptidylprolyl isomerase 0.0098 0.0538 0.1716
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0023 0.0025
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.003 0.0093 0.0251
Echinococcus multilocularis tubulin alpha 1C chain 0.0046 0.0192 0.0212
Treponema pallidum oxidoreductase 0.0044 0.0182 0.027
Trypanosoma brucei alpha tubulin 0.0046 0.0192 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.053 0.053
Echinococcus multilocularis protein tyrosine kinase 0.139 0.9073 1
Brugia malayi ImpB/MucB/SamB family protein 0.0183 0.1099 0.1197
Echinococcus multilocularis tubulin subunit TubB 0.0046 0.0192 0.0212
Giardia lamblia Gamma tubulin 0.0029 0.0085 0.0006
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0182 0.0294
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Trichomonas vaginalis apoptosis inducing factor, putative 0.0044 0.0182 0.0294
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.002
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0023 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0083 0.0134
Leishmania major hypothetical protein, conserved 0.0025 0.0058 0.0137
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0044 0.0182 0.0596
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0016 0.0018
Mycobacterium ulcerans NADH dehydrogenase 0.0044 0.0182 0.0135
Mycobacterium tuberculosis Probable reductase 0.1093 0.711 0.8958
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0033 0.0108 0.0174
Trichomonas vaginalis DNA polymerase eta, putative 0.0158 0.0934 0.1507
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0279 0.0308
Loa Loa (eye worm) hypothetical protein 0.0166 0.099 0.1078
Loa Loa (eye worm) tubulin beta-2A chain 0.0046 0.0194 0.0211
Echinococcus granulosus beta tubulin 0.0046 0.0194 0.0214
Echinococcus multilocularis tumor protein p63 0.0339 0.2127 0.2344
Echinococcus granulosus Tubulin alpha 1 chain 0.0046 0.0192 0.0212
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.082 0.5305 0.5847
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0686 0.0686
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0044 0.0182 0.0201
Echinococcus multilocularis tubulin gamma 1 chain 0.0029 0.0085 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3233
Trichomonas vaginalis set domain proteins, putative 0.0955 0.6201 1
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0279 0.0304
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0286 0.1777 0.2063
Brugia malayi Tubulin alpha-2 chain 0.0046 0.0192 0.0209
Trichomonas vaginalis tubulin alpha chain, putative 0.0046 0.0194 0.0313
Plasmodium falciparum tubulin beta chain 0.0046 0.0194 0.0585
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0175 0.0572
Brugia malayi PXA domain containing protein 0.002 0.0021 0.0023
Schistosoma mansoni glutamate synthase 0.0044 0.0182 0.0182
Onchocerca volvulus 0.005 0.0218 0.0352
Echinococcus multilocularis Tubulin alpha 1 chain 0.0046 0.0192 0.0212
Chlamydia trachomatis thioredoxin reductase 0.0044 0.0182 0.1096
Mycobacterium ulcerans hypothetical protein 0.0161 0.0953 0.4903
Schistosoma mansoni intermediate filament proteins 0.0027 0.0067 0.0067
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Brugia malayi Tubulin alpha chain 0.0046 0.0192 0.0209
Loa Loa (eye worm) hypothetical protein 0.0101 0.0556 0.0606
Echinococcus granulosus protein tyrosine kinase 0.139 0.9073 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0016 0.0018
Schistosoma mansoni hypothetical protein 0.0044 0.0182 0.0182
Echinococcus granulosus microtubule associated protein 2 0.138 0.9008 0.9928
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0195 0.0213
Brugia malayi Tubulin gamma chain 0.0029 0.0085 0.0093
Loa Loa (eye worm) tubulin alpha-2 chain 0.0046 0.0192 0.0209
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0058 0.0137
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Trypanosoma cruzi beta tubulin, putative 0.0046 0.0194 0.0635
Plasmodium vivax tubulin gamma chain, putative 0.0029 0.0085 0.0226
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0125 0.0408
Toxoplasma gondii beta-tubulin, putative 0.0046 0.0194 0.0585
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0021 0.0023
Echinococcus granulosus glutamate synthase 0.0044 0.0182 0.0201
Trichomonas vaginalis tubulin gamma chain, putative 0.0046 0.0194 0.0313
Mycobacterium leprae conserved hypothetical protein 0.0047 0.02 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0166 0.0988 1
Schistosoma mansoni hypothetical protein 0.0339 0.213 0.213
Echinococcus granulosus Tubulin beta 2C chain 0.0046 0.0194 0.0214
Trypanosoma cruzi trypanothione reductase, putative 0.0479 0.3056 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0023 0.0025
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0021 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Schistosoma mansoni glutamate synthase 0.0044 0.0182 0.0182
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.053 0.0585
Brugia malayi tubulin alpha chain - mouse 0.0046 0.0192 0.0209
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0044 0.0182 0.0546
Trypanosoma brucei beta tubulin 0.0029 0.0085 0.0276
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0023 0.0023
Leishmania major basic transcription factor 3a, putative 0.0035 0.0125 0.0356
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0016 0.0051
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0018 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Echinococcus multilocularis expressed protein 0.01 0.0553 0.061
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0182 0.0594
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0073
Echinococcus granulosus tubulin subunit TubB 0.0046 0.0192 0.0212
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0601 0.0601
Leishmania major DNA polymerase kappa, putative 0.0138 0.0802 0.2585
Echinococcus multilocularis tubulin alpha chain 0.0046 0.0192 0.0212
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0601 0.0663
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0166 0.0988 0.3196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0195 0.0195
Toxoplasma gondii alpha-tubulin I, putative 0.0046 0.0192 0.0578
Schistosoma mansoni regulator of G protein signaling 0.002 0.0021 0.0021
Brugia malayi hypothetical protein 0.0025 0.0058 0.0063
Trypanosoma brucei tubulin gamma chain 0.0029 0.0085 0.0276
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1093 0.711 0.8958
Schistosoma mansoni tubulin subunit epsilon 0.0029 0.0085 0.0085
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0044 0.0182 0.0294
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0601 0.1966
Trichomonas vaginalis glutamate synthase, putative 0.0044 0.0182 0.0294
Loa Loa (eye worm) BEN-1 protein 0.0046 0.0194 0.0211
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0021 0.0023
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0279 0.0864
Echinococcus granulosus peregrin 0.0059 0.0279 0.0308
Leishmania major DNA polymerase kappa, putative 0.0041 0.016 0.0474
Treponema pallidum fructose-bisphosphate aldolase 0.0585 0.3752 1
Onchocerca volvulus 0.0027 0.0067 0.0109
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0192 0.1161 0.128
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0016 0.0018
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0182 0.0294
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0192 0.031
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0044 0.0182 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Entamoeba histolytica hypothetical protein 0.0035 0.0125 0.0332
Trypanosoma cruzi DNA damage repair protein, putative 0.0041 0.016 0.0525
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1093 0.711 0.8958
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3233
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0016 0.0016
Loa Loa (eye worm) BEN-1 protein 0.0046 0.0194 0.0211
Trypanosoma cruzi DNA polymerase eta, putative 0.0092 0.0501 0.1641
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.007
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0021 0.0023
Mycobacterium tuberculosis Probable dehydrogenase 0.1093 0.711 0.8958
Mycobacterium ulcerans hypothetical protein 0.0044 0.0182 0.0135
Brugia malayi alpha-tubulin 0.0046 0.0192 0.0209
Brugia malayi Thioredoxin reductase 0.0479 0.3056 0.3328
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.053 0.1736
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0166 0.0988 0.1089
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0166 0.0988 0.0988
Trichomonas vaginalis tubulin, putative 0.0017 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0044 0.0182 0.0546
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0058 0.019
Trypanosoma cruzi DNA damage repair protein, putative 0.0041 0.016 0.0525
Echinococcus multilocularis peregrin 0.0059 0.0279 0.0308
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0047 0.02 0.0605
Echinococcus multilocularis tubulin beta 1 chain 0.0046 0.0194 0.0214
Schistosoma mansoni alpha tubulin 0.0046 0.0192 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.053 0.0855
Brugia malayi jmjC domain containing protein 0.0071 0.0361 0.0393
Schistosoma mansoni alpha tubulin 0.0046 0.0192 0.0192
Echinococcus multilocularis beta tubulin 0.0046 0.0194 0.0214
Giardia lamblia DNA damage repair protein 0.0041 0.016 0.0211
Brugia malayi jmjC domain containing protein 0.0192 0.1161 0.1265
Loa Loa (eye worm) TK/FAK protein kinase 0.1407 0.9182 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0108 0.0117
Plasmodium falciparum thioredoxin reductase 0.0479 0.3056 1
Trypanosoma brucei alpha tubulin 0.0046 0.0192 0.0626
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0021 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0016 0.0018
Leishmania major epsilon tubulin, putative 0.0029 0.0085 0.0226
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0083 0.022
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0083 0.022
Mycobacterium ulcerans glutamate synthase subunit beta 0.0044 0.0182 0.0135
Brugia malayi Bromodomain containing protein 0.0059 0.0279 0.0304
Echinococcus multilocularis Tubulin beta 2C chain 0.0046 0.0194 0.0214
Echinococcus granulosus expressed protein 0.01 0.0553 0.061
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1093 0.711 0.8958
Echinococcus granulosus tubulin alpha chain 0.0046 0.0192 0.0212
Trypanosoma brucei adenosine kinase, putative 0.0105 0.0585 0.1913
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.012 0.0686 0.0686
Toxoplasma gondii NADPH-glutathione reductase 0.0166 0.0988 0.3196
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0988 0.3233
Brugia malayi hypothetical protein 0.002 0.0021 0.0023
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0166 0.0988 0.1076
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0166 0.0988 0.5117
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Leishmania major DNA damage repair protein, putative 0.0041 0.016 0.0474
Loa Loa (eye worm) hypothetical protein 0.0105 0.0585 0.0637
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0182 0.0596
Loa Loa (eye worm) thioredoxin reductase 0.0479 0.3056 0.3328
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0047 0.02 0.0605
Echinococcus multilocularis tubulin alpha chain 0.0046 0.0192 0.0212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0585 0.3752 0.6051
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0125 0.0201
Trichomonas vaginalis tubulin epsilon chain, putative 0.0046 0.0192 0.031
Trichomonas vaginalis tubulin, putative 0.0046 0.0194 0.0313
Entamoeba histolytica tubulin gamma chain 0.0029 0.0085 0.0227
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0044 0.0182 0.0294
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.0018 0.0005
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0182 0.0594
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0044 0.0182 0.0201
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0023 0.0023
Entamoeba histolytica tubulin alpha-1 chain 0.0046 0.0192 0.0512
Leishmania major mitochondrial DNA polymerase beta 0.0305 0.1908 0.6222
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0044 0.0182 0.0546
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0044 0.0182 0.0201
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0047 0.0047
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0058 0.0137
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0044 0.0182 0.0201
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0044 0.0182 0.0596
Loa Loa (eye worm) hypothetical protein 0.0029 0.0082 0.009
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0044 0.0182 0.0201
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0044 0.0182 0.0594
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0601 0.097
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0279 0.0864
Brugia malayi jmjC domain containing protein 0.0019 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0044 0.0182 0.0198
Schistosoma mansoni adenosine kinase 0.0105 0.0585 0.0585
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0044 0.0182 0.0135
Echinococcus granulosus tubulin alpha chain 0.0046 0.0192 0.0212
Brugia malayi jmjC domain containing protein 0.0019 0.0016 0.0018
Trypanosoma brucei beta tubulin 0.0046 0.0194 0.0632
Schistosoma mansoni sulfide quinone reductase 0.0044 0.0182 0.0182
Giardia lamblia Alpha-tubulin 0.0046 0.0192 0.0297
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0083 0.022
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0034
Schistosoma mansoni tubulin subunit alpha 0.0046 0.0192 0.0192
Echinococcus granulosus intermediate filament protein 0.0027 0.0067 0.0074
Echinococcus granulosus beta tubulin 0.0046 0.0194 0.0214
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0361 0.0397
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0279 0.0279
Echinococcus granulosus adenosine kinase 0.0105 0.0585 0.0645
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0044 0.0182 0.0546
Trypanosoma cruzi DNA polymerase kappa, putative 0.0158 0.0934 0.3058
Plasmodium falciparum tubulin epsilon chain, putative 0.0029 0.0085 0.0226
Echinococcus multilocularis tubulin subunit beta 0.0046 0.0194 0.0214
Brugia malayi jmjC domain containing protein 0.0019 0.0016 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0601 0.097
Schistosoma mansoni tubulin subunit beta 0.0046 0.0194 0.0194
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.053 0.0578
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0058 0.019
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0361 0.0397
Echinococcus granulosus lamin 0.0027 0.0067 0.0074
Trypanosoma cruzi NADH dehydrogenase, putative 0.0044 0.0182 0.0596
Trypanosoma brucei unspecified product 0.0091 0.0489 0.1599
Entamoeba histolytica hypothetical protein 0.002 0.0021 0.0056
Trypanosoma cruzi adenosine kinase, putative 0.0105 0.0585 0.1915
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0016 0.0018
Schistosoma mansoni microtubule-associated protein tau 0.138 0.9008 0.9008
Mycobacterium ulcerans ferredoxin reductase 0.0044 0.0182 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0034
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0047 0.02 0.0246
Echinococcus granulosus transcription factor btf3 0.0035 0.0125 0.0137
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0125 0.0356
Giardia lamblia Fructose-bisphosphate aldolase 0.0585 0.3752 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0083 0.022
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.0657 0.0724
Leishmania major beta tubulin 0.0046 0.0194 0.0585
Schistosoma mansoni DNA polymerase eta 0.0183 0.1099 0.1099
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0021 0.0023
Brugia malayi Protein kinase domain containing protein 0.1407 0.9182 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0044 0.0182 0.0198
Echinococcus granulosus Tubulin alpha 1 chain 0.0046 0.0192 0.0212
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0021 0.0023
Trypanosoma brucei chrX additional, unordered contigs 0.0041 0.016 0.0522
Schistosoma mansoni glutamate synthase 0.0044 0.0182 0.0182
Trichomonas vaginalis tubulin epsilon chain, putative 0.0046 0.0194 0.0313
Plasmodium vivax thioredoxin reductase, putative 0.0479 0.3056 1
Brugia malayi Pre-SET motif family protein 0.0839 0.5435 0.592
Leishmania major alpha tubulin 0.0046 0.0192 0.0578
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0044 0.0182 0.0486
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.053 0.0855
Brugia malayi polk-prov protein 0.0067 0.0336 0.0366
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0021 0.0021
Trichomonas vaginalis mercuric reductase, putative 0.0166 0.0988 0.1593
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0208 0.0335
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0023
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.01 0.0553 0.0603
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0047 0.0051
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0192 0.031
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0934 0.3056
Echinococcus multilocularis Tubulin alpha 1 chain 0.0046 0.0192 0.0212
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0166 0.0988 0.5117
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1093 0.711 0.8958
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1215 0.7915 1
Treponema pallidum NADH oxidase 0.0166 0.0988 0.2465
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0033 0.0108 0.0117
Echinococcus multilocularis tubulin alpha chain 0.0046 0.0192 0.0212
Entamoeba histolytica deoxycytidyl transferase, putative 0.0131 0.0758 0.2021
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0044 0.0182 0.0546
Leishmania major DNA polymerase eta, putative 0.0183 0.1099 0.3564
Schistosoma mansoni regulator of G protein signaling 0.002 0.0021 0.0021
Loa Loa (eye worm) tubulin alpha chain 0.0046 0.0192 0.0209
Onchocerca volvulus 0.012 0.0686 0.1107
Loa Loa (eye worm) hypothetical protein 0.0059 0.0279 0.0304
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0098 0.0538 0.1758
Echinococcus multilocularis adenosine kinase 0.0105 0.0585 0.0645
Brugia malayi PHD-finger family protein 0.0059 0.0279 0.0304
Loa Loa (eye worm) glutathione reductase 0.0479 0.3056 0.3328
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0044 0.0182 0.0546
Echinococcus granulosus tubulin epsilon chain 0.0029 0.0085 0.0094
Giardia lamblia NADH oxidase lateral transfer candidate 0.0166 0.0988 0.2465
Echinococcus granulosus tubulin beta 4A class IVa 0.0046 0.0194 0.0214
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0194 0.0313
Trypanosoma cruzi DNA polymerase kappa, putative 0.0158 0.0934 0.3058
Echinococcus multilocularis thioredoxin glutathione reductase 0.0482 0.3073 0.3387
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0166 0.0988 0.3233
Schistosoma mansoni tubulin subunit beta 0.0046 0.0194 0.0194
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.0192 0.031
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0533 0.1742
Brugia malayi ImpB/MucB/SamB family protein 0.0131 0.0758 0.0826
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0686 0.0686
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0044 0.0182 0.0201
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0166 0.0988 0.3196
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0192 0.1161 0.128
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0021 0.0023
Trypanosoma brucei trypanothione reductase 0.0479 0.3056 1
Brugia malayi Adenosine kinase-like 0.0105 0.0585 0.0637
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0083 0.0134
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.053 0.0585
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0023 0.0025
Brugia malayi PXA domain containing protein 0.002 0.0021 0.0023
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.1908 0.6243
Trypanosoma brucei unspecified product 0.0151 0.0891 0.2913
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0237 0.0775

Activities

Activity type Activity value Assay description Source Reference
Log IC50 (binding) = 4 Concentration required for 50% inhibition of the adenosine kinase (AK) activity. ChEMBL. 15149648

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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