Detailed information for compound 175006

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 270.197 | Formula: C14H17Cl2N
  • H donors: 0 H acceptors: 0 LogP: 3.98 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCC(=CC1)CCc1ccc(c(c1)Cl)Cl
  • InChi: 1S/C14H17Cl2N/c1-17-8-6-11(7-9-17)2-3-12-4-5-13(15)14(16)10-12/h4-6,10H,2-3,7-9H2,1H3
  • InChiKey: IQJAHBUEFCXGSZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis CAAX prenyl protease 2 0.0082 0.0142 0.0135
Echinococcus multilocularis lamin dm0 0.0031 0.0032 0.0025
Entamoeba histolytica protein kinase, putative 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0056 0.0087 0.0087
Schistosoma mansoni fkbp-rapamycin associated protein 0.0869 0.1862 0.186
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0018 0.0012
Echinococcus granulosus muscleblind protein 0.0628 0.1335 0.1329
Brugia malayi nuclear receptor NHR-88 0.0053 0.008 0.008
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0056 0.0087 0.008
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0297 0.0611 1
Brugia malayi Wnt-2 protein precursor 0.0029 0.0027 0.0027
Echinococcus granulosus protein Wnt 1 0.0029 0.0027 0.0021
Echinococcus multilocularis voltage gated potassium channel 0.0033 0.0035 0.0029
Echinococcus multilocularis cpg binding protein 0.0093 0.0166 0.0159
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0034 0.0034
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0297 0.0611 0.0605
Brugia malayi nuclear receptor NHR-67 0.0025 0.0018 0.0018
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0018 0.0016
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0033 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0064 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0034 0.0556
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.008 0.0073
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0508 0.1072 0.107
Loa Loa (eye worm) phosphatidylinositol 3 0.0297 0.0611 0.0611
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.1214 0.1208
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0297 0.0611 0.0611
Echinococcus granulosus serine protein kinase ATM 0.0869 0.1862 0.1856
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.0698 0.0694
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0134 0.0129
Echinococcus granulosus CAAX prenyl protease 2 0.0082 0.0142 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0869 0.1862 0.1856
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0088 0.0156 0.0156
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0023 0.0013 0.0006
Entamoeba histolytica protein kinase 2, putative 0.002 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.3656 0.7946 0.7945
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0034 0.0029
Trichomonas vaginalis heat shock protein, putative 0.0026 0.002 0.0013
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0297 0.0611 0.0605
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0045 0.0062 0.0062
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0297 0.0611 0.0611
Echinococcus granulosus FTZ F1 alpha 0.0053 0.008 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0018 0.0012
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0089 0.0158 0.0155
Echinococcus granulosus dnaJ subfamily B 0.1248 0.2687 0.2682
Schistosoma mansoni zinc finger protein 0.0025 0.0018 0.0016
Echinococcus multilocularis zinc finger transcription factor gli2 0.0668 0.1422 0.1416
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0043
Giardia lamblia Hypothetical protein 0.0297 0.0611 0.0604
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.004 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0869 0.1862 0.1856
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0311 0.0306
Leishmania major phosphatidylinositol 3-kinase, putative 0.1541 0.3329 0.3316
Echinococcus multilocularis Niemann Pick C1 protein 0.0088 0.0155 0.0148
Echinococcus multilocularis heat shock protein 90 0.0032 0.0034 0.0027
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0012 0.0009
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0023 0.0013 0.0006
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.4596 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Echinococcus multilocularis wnt family member wnt11 2 0.0029 0.0027 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0053 0.008 0.0077
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.008 0.008
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0297 0.0611 0.0579
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0297 0.0611 0.0605
Toxoplasma gondii target of rapamycin (TOR), putative 0.3419 0.7428 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.3083 0.6696 0.6693
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0033 0.0035 0.0029
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0297 0.0611 0.0604
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0297 0.0611 0.0609
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0225 0.0455 0.0449
Brugia malayi ecdysone receptor 0.0025 0.0018 0.0018
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0297 0.0611 0.0822
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.0031
Brugia malayi hypothetical protein 0.005 0.0074 0.0074
Echinococcus multilocularis fk506 binding protein 0.0056 0.0087 0.008
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0046 0.0062
Schistosoma mansoni hypothetical protein 0.0297 0.0611 0.0609
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.031 0.0639 0.0639
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0067 0.0062
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0297 0.0611 0.0605
Onchocerca volvulus 0.0297 0.0611 0.7248
Entamoeba histolytica hypothetical protein 0.0088 0.0156 0.0156
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0243 0.0494 0.0488
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0297 0.0611 0.0609
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0045 0.0062 0.0056
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0038 0.0046 0.0046
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1541 0.3329 0.3307
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0013 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0034 0.0029
Echinococcus multilocularis thyroid hormone receptor alpha 0.0053 0.008 0.0073
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0018 0.0018
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0297 0.0611 0.0606
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0017 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0018 0.0016
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0225 0.0455 0.0453
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.008 0.0753
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0018 0.0018
Loa Loa (eye worm) DR-78 0.0025 0.0018 0.0018
Schistosoma mansoni wnt related 0.0029 0.0027 0.0025
Echinococcus granulosus endoplasmin 0.0026 0.002 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.008 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.04 0.0836 0.0836
Echinococcus multilocularis neuropeptide s receptor 0.0412 0.0863 0.0857
Schistosoma mansoni hypothetical protein 0.0036 0.0043 0.004
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1541 0.3329 0.3325
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0034 0.0029
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0095 0.2699
Loa Loa (eye worm) hypothetical protein 0.0297 0.0611 0.0611
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0046 0.075
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.3656 0.7946 0.7945
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0018 0.0018
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0046 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.1541 0.3329 0.3325
Echinococcus granulosus lamin dm0 0.0031 0.0032 0.0025
Schistosoma mansoni microtubule-associated protein tau 0.2063 0.4469 0.4467
Giardia lamblia DNA repair protein RAD52 0.031 0.0639 0.0633
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.1909 0.4132 0.4112
Schistosoma mansoni hypothetical protein 0.0508 0.1072 0.107
Schistosoma mansoni hypothetical protein 0.0036 0.0043 0.004
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0869 0.1862 0.1857
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0869 0.1862 0.1862
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0297 0.0611 0.0605
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0018 0.0012
Echinococcus multilocularis tumor protein p63 0.0335 0.0694 0.0688
Brugia malayi Protein kinase domain containing protein 0.0032 0.0034 0.0034
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0297 0.0611 0.0605
Echinococcus multilocularis endoplasmin 0.0026 0.002 0.0013
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0225 0.0455 0.0449
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0297 0.0611 0.0605
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0187 0.0372 0.0369
Echinococcus granulosus heat shock protein 0.0032 0.0034 0.0027
Echinococcus multilocularis WNT 0.0029 0.0027 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0043 0.0041
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.366 0.7955 0.7951
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0095 0.0075
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0297 0.0611 0.0605
Brugia malayi Pax transcription factor protein 2 0.0214 0.0431 0.0431
Brugia malayi steroid hormone receptor 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0032
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0579
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0025
Plasmodium falciparum endoplasmin, putative 0.002 0.0007 0.0109
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2435 0.5279 0.5276
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0337 0.0698 0.0667
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0297 0.0611 0.0611
Echinococcus granulosus neuropeptide s receptor 0.0412 0.0863 0.0857
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0134 0.0101
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0297 0.0611 0.0611
Schistosoma mansoni endoplasmin 0.0032 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0969 0.2078 0.2073
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0014 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.2482 0.5383 0.538
Echinococcus multilocularis serine protein kinase ATM 0.0869 0.1862 0.1856
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0013 0.0013
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0297 0.0611 0.0605
Entamoeba histolytica hypothetical protein 0.0225 0.0455 0.0455
Loa Loa (eye worm) hepatopoietin HPO2 0.0038 0.0046 0.0046
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0067 0.0062
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0013 0.0006
Echinococcus multilocularis sterol regulatory element binding protein 0.0038 0.0046 0.0039
Onchocerca volvulus 0.0214 0.0431 0.5053
Trichomonas vaginalis PIKK family atypical protein kinase 0.1541 0.3329 0.3325
Entamoeba histolytica hypothetical protein 0.0297 0.0611 0.0611
Trichomonas vaginalis PIKK family atypical protein kinase 0.2984 0.6479 0.6476
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Loa Loa (eye worm) nuclear hormone receptor 0.0215 0.0433 0.0433
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0297 0.0611 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0017 0.0017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1541 0.3329 0.3329
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0025 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0067 0.0062
Trichomonas vaginalis endoplasmin, putative 0.002 0.0007 0.0000070047
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0056 0.0087 0.008
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.008 0.0073
Schistosoma mansoni smad 0.0024 0.0017 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Giardia lamblia GTOR 0.4596 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0095 0.2699
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0018 0.0012
Chlamydia trachomatis hypothetical protein 0.0017 0 0.5
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0046 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.1541 0.3329 0.3325
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0297 0.0611 0.0605
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0611
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0297 0.0611 0.0605
Echinococcus granulosus Protein Wnt-11b 0.0029 0.0027 0.0021
Loa Loa (eye worm) hypothetical protein 0.0218 0.0439 0.0439
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.4596 1 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0311 0.0292
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.008 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0124 0.0235 0.0232
Onchocerca volvulus 0.0297 0.0611 0.7248
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.008 0.0073
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0082 0.0142 0.0139
Brugia malayi hypothetical protein 0.0025 0.0018 0.0018
Echinococcus granulosus expressed conserved protein 0.0082 0.0143 0.0137
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0297 0.0611 0.0605
Schistosoma mansoni thyroid hormone receptor 0.0053 0.008 0.0077
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0297 0.0611 0.0606
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0114 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0049 0.007 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.0098 0.0178 0.0178
Echinococcus multilocularis rac serine:threonine kinase 0.0022 0.0012 0.0005
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0672 0.1431 0.1425
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0297 0.0611 0.0592
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0049 0.007 0.0063
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0018 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.008 0.0077
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0012 0.0011
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0017 0.001
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0056 0.0087 0.0084
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0032 0.0032
Loa Loa (eye worm) endoplasmin 0.0032 0.0034 0.0034
Trypanosoma brucei CAAX amino terminal protease, putative 0.0082 0.0142 0.0108
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.007 0.0068
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0297 0.0611 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0159 0.0311 0.0279
Echinococcus multilocularis protein Wnt 1 0.0029 0.0027 0.0021
Entamoeba histolytica protein kinase, putative 0.0032 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0869 0.1862 0.1862
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0018 0.0012
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0297 0.0611 0.0605
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0297 0.0611 0.0605
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.008 0.0077
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0297 0.0611 0.0605
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1541 0.3329 0.3307
Schistosoma mansoni Smad4 0.0024 0.0017 0.0014
Echinococcus multilocularis survival motor neuron protein 1 0.0746 0.1593 0.1587
Toxoplasma gondii histone lysine methyltransferase SET1 0.0167 0.0328 0.0442
Schistosoma mansoni endoplasmin 0.0032 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Echinococcus multilocularis protein patched 0.0038 0.0046 0.0039
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0013 0.0006
Brugia malayi CXXC zinc finger family protein 0.0088 0.0155 0.0155
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Echinococcus granulosus intermediate filament protein 0.0031 0.0032 0.0025
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.4596 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0143 0.0277 0.0277
Echinococcus multilocularis geminin 0.0508 0.1072 0.1066
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0297 0.0611 0.0822
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.0078 0.0134 0.0115
Loa Loa (eye worm) hypothetical protein 0.0573 0.1214 0.1214
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0297 0.0611 0.0605
Brugia malayi Smad1 0.0024 0.0017 0.0017
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0297 0.0611 0.0606
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0095 0.1548
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.008 0.0073
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Brugia malayi hypothetical protein 0.0078 0.0134 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.008 0.008
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0869 0.1862 0.1856
Brugia malayi ecdysteroid receptor 0.0053 0.008 0.008
Loa Loa (eye worm) Wnt2 protein 0.0029 0.0027 0.0027
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0297 0.0611 0.0606
Trypanosoma brucei target of rapamycin kinase 3, putative 0.366 0.7955 0.7948
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0056 0.0087 0.008
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0297 0.0611 0.0605
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0046 0.0041
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0017 0.0014
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0869 0.1862 0.1856
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Giardia lamblia Phosphatidylinositol 4-kinase 0.0297 0.0611 0.0604
Loa Loa (eye worm) phosphatidylinositol 3 0.4596 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0358 0.0746 0.0746
Brugia malayi Pre-SET motif family protein 0.0037 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0088 0.0155 0.0155
Brugia malayi Niemann-Pick C1 protein precursor 0.0088 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Trichomonas vaginalis heat shock protein, putative 0.0026 0.002 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.008 0.008
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0095 0.0092
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0611
Onchocerca volvulus 0.0049 0.007 0.0636
Trypanosoma cruzi target of rapamycin kinase 3 0.366 0.7955 0.7954
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0297 0.0611 0.0606
Loa Loa (eye worm) AGC/AKT protein kinase 0.0032 0.0034 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0013 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0014 0.0007
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.0225 0.0455 0.0455
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0056 0.0087 0.0086
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0606
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0869 0.1862 0.1857
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0017 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Echinococcus granulosus microtubule associated protein 2 0.2063 0.4469 0.4465
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0082 0.0142 0.0137
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Echinococcus granulosus Protein patched homolog 1 0.0038 0.0046 0.0039
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0297 0.0611 0.0609
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0025 0.0018
Leishmania major phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0592
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0013 0.001
Brugia malayi wnt family protein 0.0029 0.0027 0.0027
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0045 0.0062 0.0056
Toxoplasma gondii hypothetical protein 0.0054 0.0082 0.011
Schistosoma mansoni wnt related 0.0029 0.0027 0.0025
Echinococcus granulosus Protein Wnt-04 0.0029 0.0027 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0869 0.1862 0.1856
Schistosoma mansoni hypothetical protein 0.0036 0.0043 0.004
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.002 0.0015
Entamoeba histolytica hypothetical protein 0.0225 0.0455 0.0455
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.008 0.0073
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0297 0.0611 0.0605
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0297 0.0611 0.0605
Echinococcus multilocularis neuropeptide receptor A26 0.0412 0.0863 0.0857
Brugia malayi Zinc finger, C2H2 type family protein 0.0668 0.1422 0.1422
Loa Loa (eye worm) hypothetical protein 0.0045 0.0062 0.0062
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0025 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Trichomonas vaginalis PIKK family atypical protein kinase 0.2482 0.5383 0.538
Schistosoma mansoni nuclear receptor 0.0025 0.0018 0.0016
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0022 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0672 0.1431 0.1431
Trichomonas vaginalis PIKK family atypical protein kinase 0.2478 0.5375 0.5371
Mycobacterium leprae conserved hypothetical protein 0.0297 0.0611 1
Plasmodium vivax SET domain protein, putative 0.0037 0.0043 0.0707
Loa Loa (eye worm) zinc finger protein 0.0668 0.1422 0.1422
Brugia malayi hypothetical protein 0.0028 0.0025 0.0025
Loa Loa (eye worm) Smad1 0.0024 0.0017 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0114 0.0212 0.0205
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0297 0.0611 1
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0056 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0869 0.1862 0.186
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0297 0.0611 0.0609
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0018 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0297 0.0611 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Brugia malayi wnt family protein 0.0029 0.0027 0.0027
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1541 0.3329 0.3328
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.0698 0.0694
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.4596 1 1
Plasmodium vivax endoplasmin, putative 0.0032 0.0034 0.0556
Brugia malayi MH2 domain containing protein 0.0024 0.0017 0.0017
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.008 0.0073
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0018 0.0012
Onchocerca volvulus 0.0031 0.0032 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0025
Echinococcus granulosus cpg binding protein 0.0093 0.0166 0.0159
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.008 0.0753
Onchocerca volvulus 0.0031 0.0032 0.0165
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0018 0.0016
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0869 0.1862 0.1862
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0095 0.0092
Loa Loa (eye worm) hypothetical protein 0.0033 0.0035 0.0035
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0134 0.2194
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0018 0.0012
Echinococcus granulosus Protein Wnt-5 0.0029 0.0027 0.0021
Trypanosoma cruzi Protein kinase B 0.0022 0.0012 0.0006
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0082 0.0142 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.2719 0.5901 0.5898
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0034 0.0034
Treponema pallidum heat shock protein 90 0.0026 0.002 0.2266
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.008 0.0073
Echinococcus granulosus Niemann Pick C1 protein 0.0125 0.0237 0.023
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0056 0.0087 0.0087
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1541 0.3329 0.3316
Schistosoma mansoni hypothetical protein 0.0035 0.004 0.0037
Mycobacterium tuberculosis Conserved hypothetical protein 0.0297 0.0611 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0143 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus granulosus survival motor neuron protein 1 0.0746 0.1593 0.1587
Brugia malayi CHE-14 protein 0.0038 0.0046 0.0046
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.008 0.008
Loa Loa (eye worm) wnt-4 protein 0.0029 0.0027 0.0027
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.008 0.0073
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.008 0.0753
Schistosoma mansoni coup transcription factor 0.0053 0.008 0.0077
Onchocerca volvulus Huntingtin homolog 0.04 0.0836 1
Brugia malayi p70 ribosomal S6 kinase beta 0.003 0.0029 0.0029
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0012 0.0009
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0018 0.0018
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0056 0.0087 1
Brugia malayi Wnt-4 protein precursor 0.0029 0.0027 0.0027
Brugia malayi wnt family protein 0.0029 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.1248 0.2687 0.2686
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.008 0.0073
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0056 0.0087 0.1414
Leishmania major phosphatidylinositol kinase related protein, putative 0.0297 0.0611 0.0592
Brugia malayi Cyclic-nucleotide gated cation channel 0.0023 0.0013 0.0013
Brugia malayi nuclear hormone receptor 0.0025 0.0018 0.0018
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Schistosoma mansoni lamin 0.0031 0.0032 0.0029
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0013 0.001
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Plasmodium vivax hypothetical protein 0.0297 0.0611 1
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0034 0.0029
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0297 0.0611 0.0605
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.008 0.0073
Toxoplasma gondii AGC kinase 0.003 0.0029 0.0039
Brugia malayi CAAX amino terminal protease family protein 0.0082 0.0142 0.0142
Brugia malayi Calcitonin receptor-like protein seb-1 0.0143 0.0277 0.0277
Schistosoma mansoni lamin 0.0031 0.0032 0.0029
Echinococcus multilocularis Zinc finger, PHD finger 0.0297 0.0611 0.0605
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.006
Mycobacterium ulcerans hypothetical protein 0.0177 0.0351 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.008 0.0077
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0056 0.0087 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.008 0.008
Brugia malayi FAT domain containing protein 0.0672 0.1431 0.1431
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0017
Entamoeba histolytica protein kinase rad3, putative 0.0869 0.1862 0.1862
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1541 0.3329 0.3326
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0034 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0155 0.0155
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0018 0.0016
Loa Loa (eye worm) phosphatidylinositol 3 0.0297 0.0611 0.0611
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0297 0.0611 0.0605
Loa Loa (eye worm) hypothetical protein 0.0098 0.0178 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.2482 0.5383 0.538
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.2478 0.5375 0.5371
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.002 0.0012
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0297 0.0611 0.0604
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0017 0.001
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.008 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0297 0.0611 0.0605
Brugia malayi hypothetical protein 0.0028 0.0025 0.0025
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0056 0.0087 0.0086
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0089 0.0084
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0297 0.0611 0.0606
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.004 0.0033
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0134 0.2194
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0034 0.0029
Echinococcus granulosus sterol regulatory element binding protein 0.0038 0.0046 0.0039
Echinococcus multilocularis protein dispatched 1 0.0043 0.0057 0.005
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0297 0.0611 0.0822
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.008 0.008
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0056 0.0087 0.0081
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0095 0.0088
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0025 0.0025
Trichomonas vaginalis fk506-binding protein, putative 0.0056 0.0087 0.008
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0869 0.1862 0.1834
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0027
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0013 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0043 0.0041
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0034 0.0046
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.006
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0134 0.0129
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0297 0.0611 0.0605
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0043 0.0037
Schistosoma mansoni voltage-gated potassium channel 0.0124 0.0235 0.0232
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0297 0.0611 0.0606
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.002 0.0007 0.0116
Schistosoma mansoni wnt related 0.0029 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Echinococcus multilocularis muscleblind protein 0.0628 0.1335 0.1329
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.008 0.0077
Echinococcus granulosus zinc finger transcription factor gli2 0.0668 0.1422 0.1416
Trichomonas vaginalis PIKK family atypical protein kinase 0.4596 1 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.002 0.0321
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0056 0.0087 0.0053
Schistosoma mansoni nuclear receptor 0.0025 0.0018 0.0016
Schistosoma mansoni hypothetical protein 0.0036 0.0043 0.004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0297 0.0611 0.0611
Giardia lamblia Grp94/Hsp90 0.0026 0.002 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.4596 1 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0179 0.0179
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0297 0.0611 0.0611
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.008 0.0073
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0025 0.0022
Echinococcus granulosus Smad4 0.0024 0.0017 0.001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0106 0.0196 0.0189
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0056 0.0087 0.0053
Brugia malayi wnt family protein 0.0029 0.0027 0.0027
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0573 0.1214 0.121
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.008 0.008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0056 0.0087 0.0081
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.4596 1 1
Echinococcus granulosus voltage gated potassium channel 0.0033 0.0035 0.0029
Schistosoma mansoni heat shock protein 0.0032 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0046 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.2747 0.5961 0.5958
Echinococcus granulosus heat shock protein 90 0.0026 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0025
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0023 0.0013 0.0006
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0297 0.0611 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0013 0.0006
Brugia malayi nuclear receptor RXR 0.0028 0.0025 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0035 0.0033
Loa Loa (eye worm) pax transcription factor protein 2 0.0214 0.0431 0.0431
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.008 0.008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0244 0.0496 0.0496
Leishmania major hypothetical protein, unknown function 0.0297 0.0611 0.0592
Schistosoma mansoni heat shock protein 0.0032 0.0034 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.3656 0.7946 0.7945
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0611
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0611
Loa Loa (eye worm) hypothetical protein 0.0628 0.1335 0.1335
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0034 0.0027
Echinococcus granulosus heat shock protein 90 0.0032 0.0034 0.0027
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Schistosoma mansoni hypothetical protein 0.0098 0.0178 0.0175
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0043 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.008 0.008
Loa Loa (eye worm) phosphatidylinositol kinase 0.0297 0.0611 0.0611
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0142
Entamoeba histolytica hypothetical protein 0.0225 0.0455 0.0455
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.003 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0013
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0056 0.0087 0.008
Echinococcus multilocularis wingless type MMTV integration site family 0.0029 0.0027 0.0021
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0045 0.0062 0.0056
Onchocerca volvulus 0.0277 0.0569 0.6733
Trichomonas vaginalis conserved hypothetical protein 0.0573 0.1214 0.1208
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.002 0.0007 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.3656 0.7946 0.7945
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0046 0.0041
Echinococcus granulosus tumor protein p63 0.0335 0.0694 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.4596 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.008 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0035 0.0033
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0297 0.0611 0.0611
Loa Loa (eye worm) hypothetical protein 0.04 0.0836 0.0836
Onchocerca volvulus 0.0152 0.0296 0.3392
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0036 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.1541 0.3329 0.3325
Echinococcus granulosus protein Wnt 2 0.0029 0.0027 0.0021
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0297 0.0611 0.0609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.008 0.008
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0297 0.0611 0.0609
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0082 0.0142 0.0135
Brugia malayi Latrophilin receptor protein 2 0.0045 0.0062 0.0062
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0017
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.008 0.0077
Echinococcus granulosus lamin 0.0031 0.0032 0.0025
Leishmania major phosphatidylinositol kinase, putative 0.0297 0.0611 0.0592
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0297 0.0611 0.0609
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0297 0.0611 1
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0034 0.0034
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0106 0.0196 0.0189
Schistosoma mansoni intermediate filament proteins 0.0031 0.0032 0.0029
Brugia malayi nuclear receptor NHR-88 0.0025 0.0018 0.0018
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.4596 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.008 0.0077
Echinococcus granulosus neuropeptide receptor A26 0.0412 0.0863 0.0857
Echinococcus granulosus GPCR family 2 0.0045 0.0062 0.0056
Trichomonas vaginalis set domain proteins, putative 0.0277 0.0569 0.0562
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Echinococcus multilocularis musashi 0.0031 0.0032 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0243 0.0494 0.0488
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0013 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2174 0.471 0.4692
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0014 0.0007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0025 0.0019
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0049 0.007 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.008 0.008
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0018 0.0016
Onchocerca volvulus Huntingtin homolog 0.04 0.0836 1
Brugia malayi MH2 domain containing protein 0.0358 0.0746 0.0746
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0034 0.0027
Loa Loa (eye worm) phosphatidylinositol 3 0.1541 0.3329 0.3329
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.4596 1 1
Loa Loa (eye worm) hypothetical protein 0.0746 0.1593 0.1593
Echinococcus multilocularis GPCR, family 2 0.0045 0.0062 0.0056
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0018 0.0012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.008 0.008
Echinococcus multilocularis lamin 0.0031 0.0032 0.0025
Echinococcus multilocularis expressed conserved protein 0.0082 0.0143 0.0137
Leishmania major peptidylprolyl isomerase-like protein 0.0056 0.0087 0.0067
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0297 0.0611 0.0605
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0095 0.0088
Echinococcus multilocularis protein Wnt 2 0.0029 0.0027 0.0021
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0013 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0297 0.0611 0.0611
Schistosoma mansoni wnt related 0.0029 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Echinococcus multilocularis Niemann Pick C1 protein 0.0125 0.0237 0.023
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.008 0.0073
Plasmodium falciparum heat shock protein 90 0.0032 0.0034 0.0556
Brugia malayi MH2 domain containing protein 0.0024 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Echinococcus multilocularis WNT 0.0029 0.0027 0.0021
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0045 0.0062 0.0056
Entamoeba histolytica CAAX prenyl protease family 0.0082 0.0142 0.0141
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0297 0.0611 0.0611
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0018 0.0018
Schistosoma mansoni patched 1 0.0038 0.0046 0.0043
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.008 0.0073
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0025 0.0022
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0017 0.001
Schistosoma mansoni cpg binding protein 0.0093 0.0166 0.0163
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0082 0.0142 0.0139
Leishmania major fk506-binding protein 1-like protein 0.0056 0.0087 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.008 0.008
Brugia malayi heat shock protein 90 0.0032 0.0034 0.0034
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0152 0.0296 0.0296
Entamoeba histolytica hypothetical protein 0.0297 0.0611 0.0611
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.4596 1 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.008 0.008
Echinococcus granulosus serine/threonine protein kinase 0.0022 0.0012 0.0005
Brugia malayi Augmenter of liver regeneration 0.0038 0.0046 0.0046
Brugia malayi nuclear hormone receptor 0.0053 0.008 0.008
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0056 0.0087 0.0079
Echinococcus granulosus Niemann Pick C1 protein 0.0088 0.0155 0.0148
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Echinococcus multilocularis Smad4 0.0024 0.0017 0.001
Loa Loa (eye worm) phosphatidylinositol 3 0.0297 0.0611 0.0611
Loa Loa (eye worm) FKBP5 protein 0.0056 0.0087 0.0087
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0095 0.2699
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.4596 1 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0046 0.0041
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.008 0.0077
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0013 0.001
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.008 0.008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.008 0.0077
Brugia malayi Pre-SET motif family protein 0.0244 0.0496 0.0496
Echinococcus granulosus Protein Wnt-111 0.0029 0.0027 0.0021
Onchocerca volvulus 0.0037 0.0043 0.0306
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0025 0.0025
Onchocerca volvulus 0.0053 0.008 0.0753
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Brugia malayi hypothetical protein 0.0225 0.0455 0.0455
Brugia malayi Steroid receptor seven-up type 2 0.0243 0.0494 0.0494
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0018 0.0012
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0297 0.0611 0.0605
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0082 0.0142 0.0137
Trichomonas vaginalis heat shock protein, putative 0.002 0.0007 0.0000070047
Trichomonas vaginalis PIKK family atypical protein kinase 0.2478 0.5375 0.5371
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.002 0.5
Brugia malayi Endoplasmin precursor 0.0032 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.2747 0.5961 0.5958
Echinococcus multilocularis microtubule associated protein 2 0.2063 0.4469 0.4465
Trichomonas vaginalis heat shock protein, putative 0.0026 0.002 0.0013
Loa Loa (eye worm) transcription factor SMAD2 0.0358 0.0746 0.0746
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0013 0.0013
Schistosoma mansoni immunophilin 0.0049 0.007 0.0067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0018 0.0012
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0023 0.0013 0.0006
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0014 0.0007
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0067 0.0033
Brugia malayi hypothetical protein 0.0746 0.1593 0.1593
Loa Loa (eye worm) hypothetical protein 0.0078 0.0134 0.0134
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0969 0.2078 0.2798
Schistosoma mansoni wnt-5 0.0029 0.0027 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0043 0.0041
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0046 0.075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.008 0.008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0088 0.0155 0.0155
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0297 0.0611 0.0579
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1541 0.3329 0.3325
Loa Loa (eye worm) CWN-2 protein 0.0029 0.0027 0.0027
Leishmania major hypothetical protein, conserved 0.0038 0.0046 0.0026
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0043 0.0037
Schistosoma mansoni cpg binding protein 0.0088 0.0155 0.0152
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0056 0.0087 0.008
Echinococcus granulosus geminin 0.0508 0.1072 0.1066
Leishmania major phosphatidylinositol 4-kinase, putative 0.0297 0.0611 0.0592
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0018 0.0012
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0297 0.0611 1
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.002 0.0015
Loa Loa (eye worm) phosphatidylinositol 3 0.0297 0.0611 0.0611
Loa Loa (eye worm) latrophilin receptor protein 2 0.0045 0.0062 0.0062
Loa Loa (eye worm) phosphatidylinositol 3 0.0297 0.0611 0.0611
Schistosoma mansoni transcription factor LCR-F1 0.0225 0.0455 0.0453
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1541 0.3329 0.3326
Echinococcus multilocularis smad 0.0024 0.0017 0.001
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0033 0.0035 0.0029
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.008 0.0073
Leishmania major hypothetical protein, conserved 0.0297 0.0611 0.0592
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0869 0.1862 0.1862
Trichomonas vaginalis PIKK family atypical protein kinase 0.1541 0.3329 0.3325
Loa Loa (eye worm) hypothetical protein 0.0937 0.2009 0.2009
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Trypanosoma cruzi rac serine-threonine kinase, putative 0.002 0.0007 0.0002
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.4596 1 1
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0056 0.0087 0.1414
Leishmania major heat shock protein 83-1 0.0032 0.0034 0.0014
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0114 0.0212 0.0212
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0056 0.0087 0.0081
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0013 0.0006
Schistosoma mansoni hypothetical protein 0.0152 0.0296 0.0293
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0297 0.0611 0.0605
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0297 0.0611 0.0611
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0053 0.008 0.0077
Entamoeba histolytica hypothetical protein 0.0297 0.0611 0.0611
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0297 0.0611 0.0611
Schistosoma mansoni cpg binding protein 0.0093 0.0166 0.0163
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0297 0.0611 0.0579
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.4596 1 1
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0134 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0672 0.1431 0.1425
Toxoplasma gondii FATC domain-containing protein 0.0869 0.1862 0.2506
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0628 0.1335 0.1335
Echinococcus multilocularis 0.0297 0.0611 0.0605
Echinococcus multilocularis heat shock protein 0.0032 0.0034 0.0027
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0034 0.0046
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0297 0.0611 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.2719 0.5901 0.5898
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0297 0.0611 0.0606
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0014
Brugia malayi hypothetical protein 0.04 0.0836 0.0836
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0043 0.0037
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0056 0.0087 0.2465
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0134 0.2194
Loa Loa (eye worm) hypothetical protein 0.0869 0.1862 0.1862
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0023 0.0013 0.0006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0012 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.2747 0.5961 0.5958
Trichomonas vaginalis immunophilin, putative 0.0056 0.0087 0.008
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0095 0.0127
Brugia malayi hypothetical protein 0.0025 0.0018 0.0018
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0297 0.0611 0.0606
Entamoeba histolytica protein kinase, putative 0.003 0.0029 0.0029
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0297 0.0611 0.0611
Loa Loa (eye worm) hypothetical protein 0.0038 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.3924 0.8532 0.8531
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0043 0.0041
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.006
Loa Loa (eye worm) hypothetical protein 0.0053 0.008 0.008
Leishmania major mitochondrial DNA polymerase beta 0.0337 0.0698 0.068
Entamoeba histolytica hypothetical protein 0.0297 0.0611 0.0611
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0025 0.0025
Onchocerca volvulus 0.0088 0.0155 0.1667
Echinococcus multilocularis muscleblind protein 1 0.0628 0.1335 0.1329
Brugia malayi tailless protein 0.0025 0.0018 0.0018
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0297 0.0611 0.0822
Echinococcus granulosus smad 0.0024 0.0017 0.001
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0038 0.0046 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.3419 0.7428 0.7426
Trichomonas vaginalis PIKK family atypical protein kinase 0.2482 0.5383 0.538
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0672 0.1431 0.1425
Trichomonas vaginalis PIKK family atypical protein kinase 0.1233 0.2656 0.2651
Mycobacterium ulcerans heat shock protein 90 0.0026 0.002 0.0559
Brugia malayi conserved hypotetical protein 0.0025 0.0018 0.0018
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0297 0.0611 0.0822
Trichomonas vaginalis PIKK family atypical protein kinase 0.3656 0.7946 0.7945
Schistosoma mansoni immunophilin 0.0056 0.0087 0.0084
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0297 0.0611 0.0605
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0013 0.001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0177 0.0351 0.5737
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0297 0.0611 0.0605
Loa Loa (eye worm) hypothetical protein 0.0049 0.007 0.007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0014 0.0011
Brugia malayi Muscleblind-like protein 0.0628 0.1335 0.1335
Brugia malayi intermediate filament protein 0.0031 0.0032 0.0032
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0038 0.0046 0.0039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0297 0.0611 0.0611
Schistosoma mansoni hypothetical protein 0.0672 0.1431 0.1429
Echinococcus multilocularis dnaJ subfamily B 0.1248 0.2687 0.2682
Loa Loa (eye worm) hypothetical protein 0.0143 0.0277 0.0277
Schistosoma mansoni survival motor neuron protein 0.0152 0.0296 0.0293
Loa Loa (eye worm) hypothetical protein 0.0969 0.2078 0.2078
Brugia malayi nuclear receptor RXR 0.0025 0.0018 0.0018
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0056 0.0087 0.0081
Giardia lamblia Hypothetical protein 0.0082 0.0142 0.0134
Echinococcus multilocularis heat shock protein 90 0.0026 0.002 0.0013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0114 0.0212 0.0205
Schistosoma mansoni immunophilin 0.0056 0.0087 0.0084

Activities

Activity type Activity value Assay description Source Reference
Km (binding) 0 uM Kinetic constant (Km) of the compound determined in rat brain mitochondria; ND = Not determined ChEMBL. 2258899
Ratio (binding) 0 Ratio of Kinetic constants (Km) to that of (Vmax) was determined; ND = Not determined ChEMBL. 2258899
Vmax (binding) 0 (nM of H202) min-1 (ug of protein)-1 Kinetic constant (Vmax) of the compound determined in rat brain mitochondria; ND = Not determined ChEMBL. 2258899

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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