Detailed information for compound 188122

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.263 | Formula: C17H13Cl2NS
  • H donors: 0 H acceptors: 1 LogP: 5.98 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1cc(C)nc2c1cccc2c1ccc(cc1Cl)Cl
  • InChi: 1S/C17H13Cl2NS/c1-10-8-16(21-2)14-5-3-4-13(17(14)20-10)12-7-6-11(18)9-15(12)19/h3-9H,1-2H3
  • InChiKey: RJBIUSLAWHJLED-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens corticotropin releasing hormone receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative Get druggable targets OG5_130760 All targets in OG5_130760
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 Get druggable targets OG5_130760 All targets in OG5_130760
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 Get druggable targets OG5_130760 All targets in OG5_130760
Schistosoma japonicum IPR001879,Hormone receptor, extracellular,domain-containing Get druggable targets OG5_130760 All targets in OG5_130760
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130760 All targets in OG5_130760
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c corticotropin releasing hormone receptor 1 444 aa 445 aa 25.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Onchocerca volvulus 0.0036 0.046 0.1359
Echinococcus granulosus lamin 0.0022 0.0213 0.0206
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0213 0.0467
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0599 0.1777
Echinococcus multilocularis expressed protein 0.0028 0.0308 0.0301
Onchocerca volvulus Chorion peroxidase homolog 0.0054 0.0769 0.229
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Echinococcus granulosus hypothetical protein 0.0023 0.0217 0.021
Echinococcus granulosus tubulin beta 1 chain 0.0049 0.0678 0.0671
Echinococcus multilocularis muscleblind protein 0.014 0.2288 0.2283
Trichomonas vaginalis tubulin alpha chain, putative 0.0026 0.0279 0.0812
Brugia malayi Tubulin alpha-2 chain 0.0026 0.0279 0.059
Trypanosoma brucei unspecified product 0.0016 0.01 0.1171
Loa Loa (eye worm) animal heme peroxidase 0.0054 0.0769 0.1685
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0077 0.017
Mycobacterium ulcerans hypothetical protein 0.0014 0.006 0.0609
Plasmodium falciparum heat shock protein 90 0.0054 0.0775 1
Brugia malayi intermediate filament protein 0.0022 0.0213 0.0445
Giardia lamblia Grp94/Hsp90 0.0043 0.0579 0.7443
Mycobacterium ulcerans carboxylesterase, LipT 0.0017 0.0123 0.1388
Loa Loa (eye worm) hypothetical protein 0.0037 0.0476 0.1043
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0279 0.0812
Trypanosoma cruzi beta tubulin, putative 0.0049 0.0678 0.8736
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Entamoeba histolytica tubulin gamma chain 0.0026 0.0279 0.3517
Loa Loa (eye worm) hypothetical protein 0.0019 0.0152 0.0334
Brugia malayi Animal haem peroxidase family protein 0.0054 0.0769 0.1666
Trichomonas vaginalis tubulin gamma chain, putative 0.0011 0.0017 0.0018
Entamoeba histolytica hypothetical protein 0.003 0.0346 0.4392
Giardia lamblia Epsilon tubulin 0.0011 0.0017 0.008
Echinococcus granulosus GPCR family 2 0.0019 0.0152 0.0145
Onchocerca volvulus 0.0015 0.0078 0.0203
Brugia malayi hypothetical protein 0.003 0.0346 0.0737
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0381 0.4855
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.004 0.0525 0.6352
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0017 0.0123 0.0113
Brugia malayi Carboxylesterase family protein 0.0017 0.0123 0.0247
Echinococcus granulosus RUN 0.002 0.0161 0.0153
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Trypanosoma cruzi DNA polymerase eta, putative 0.0026 0.028 0.352
Trypanosoma cruzi metacaspase, putative 0.0044 0.0599 0.7697
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0265 0.0255
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.073 0.0721
Onchocerca volvulus 0.0022 0.0213 0.0612
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0011 0.0011 0.0003
Loa Loa (eye worm) tubulin beta chain 0.0011 0.0017 0.0037
Echinococcus multilocularis muscleblind protein 1 0.014 0.2288 0.2283
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0016 0.01 0.1104
Loa Loa (eye worm) tubulin beta-4 chain 0.0049 0.0678 0.1486
Echinococcus granulosus peroxidasin 0.0054 0.0769 0.0762
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0011 0.0017 0.0018
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.01 0.1171
Onchocerca volvulus 0.0017 0.0123 0.034
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0027 0.0297 0.3743
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Brugia malayi Cytochrome P450 family protein 0.0015 0.0077 0.0147
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0011 0.0017 0.0075
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Schistosoma mansoni lipoxygenase 0.0117 0.1881 0.1873
Echinococcus multilocularis lamin dm0 0.0022 0.0213 0.0206
Onchocerca volvulus 0.0054 0.0769 0.229
Entamoeba histolytica tubulin family protein 0.0049 0.0678 0.8736
Giardia lamblia Heat shock protein HSP 90-alpha 0.0054 0.0775 1
Onchocerca volvulus 0.0017 0.0123 0.034
Trypanosoma cruzi heat shock protein 90, putative 0.0054 0.0775 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0016 0.0103 0.1137
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0048 0.0495
Echinococcus granulosus neuroligin 0.0017 0.0123 0.0116
Echinococcus multilocularis tubulin epsilon chain 0.0026 0.0279 0.0272
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0599 0.7697
Echinococcus granulosus caspase 3 0.0121 0.1962 0.1956
Trichomonas vaginalis aldehyde oxidase, putative 0.0085 0.1321 0.3958
Trypanosoma brucei heat shock protein 90, putative 0.0054 0.0775 1
Entamoeba histolytica hypothetical protein 0.003 0.0346 0.4392
Loa Loa (eye worm) hypothetical protein 0.0044 0.0599 0.1312
Echinococcus multilocularis protein quaking 0.0023 0.0217 0.021
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0026 0.0279 0.0812
Echinococcus granulosus dna polymerase eta 0.0037 0.0476 0.0469
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0085 0.1321 0.3958
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0016 0.01 0.0219
Entamoeba histolytica hypothetical protein 0.003 0.0346 0.4392
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0029 0.0324 0.3864
Trypanosoma brucei alpha tubulin 0.0026 0.0279 0.3517
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.0775 1
Trypanosoma cruzi heat shock protein 85, putative 0.0043 0.0579 0.7443
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0043 0.0579 0.7021
Giardia lamblia Beta tubulin 0.0049 0.0678 0.8736
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0043 0.0579 0.0572
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0036 0.046 0.0453
Echinococcus granulosus intermediate filament protein 0.0022 0.0213 0.0206
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Echinococcus multilocularis heat shock protein 90 0.0043 0.0579 0.0572
Echinococcus multilocularis isocitrate dehydrogenase 0.0013 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0279 0.0612
Trypanosoma brucei zeta tubulin 0.0011 0.0017 0.008
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0013 0.0048 0.0495
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Echinococcus multilocularis dna polymerase eta 0.0037 0.0476 0.0469
Brugia malayi Tubulin beta-1 chain 0.0049 0.0678 0.1467
Plasmodium falciparum tubulin gamma chain 0.0026 0.0279 0.3517
Echinococcus multilocularis tubulin alpha chain 0.0026 0.0279 0.0272
Brugia malayi Trypsin family protein 0.0036 0.046 0.0988
Onchocerca volvulus Cell death protein 3 homolog 0.0044 0.0599 0.1777
Loa Loa (eye worm) tubulin alpha-2 chain 0.0026 0.0279 0.0612
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0022 0.0208 0.0597
Echinococcus multilocularis tubulin alpha 1C chain 0.0026 0.0279 0.0272
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0029 0.0324 0.3864
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0599 0.1777
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Echinococcus granulosus caspase 2 0.0044 0.0599 0.0592
Trypanosoma brucei epsilon tubulin 0.0026 0.0279 0.3517
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0028 0.0039
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Brugia malayi Carboxylesterase family protein 0.0017 0.0123 0.0247
Trichomonas vaginalis DNA polymerase eta, putative 0.0016 0.01 0.027
Plasmodium vivax endoplasmin, putative 0.0054 0.0775 1
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0279 0.0812
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0057 0.082 1
Schistosoma mansoni endoplasmin 0.0054 0.0775 0.0765
Echinococcus multilocularis tubulin alpha 3 chain 0.0026 0.0279 0.0272
Echinococcus multilocularis musashi 0.0022 0.0213 0.0206
Giardia lamblia DINP protein human, muc B family 0.0016 0.01 0.1171
Plasmodium vivax metacaspase 1, putative 0.0044 0.0599 0.7697
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Echinococcus multilocularis caspase 0.0166 0.2745 0.274
Brugia malayi Isocitrate dehydrogenase 0.0013 0.0048 0.0083
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0013 0.0048 0.0495
Schistosoma mansoni neuroligin 3 (S09 family) 0.0017 0.0123 0.0113
Echinococcus granulosus Tubulin alpha 1 chain 0.0026 0.0279 0.0272
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.003 0.0346 0.0339
Loa Loa (eye worm) hypothetical protein 0.0041 0.0545 0.1195
Giardia lamblia Alpha-tubulin 0.0026 0.0279 0.3517
Brugia malayi Carboxylesterase family protein 0.0103 0.1637 0.3574
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Echinococcus multilocularis tubulin alpha 0.0026 0.0279 0.0272
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0018
Schistosoma mansoni lipoxygenase 0.0082 0.126 0.125
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Trypanosoma cruzi heat shock protein, putative 0.0022 0.0208 0.2588
Trypanosoma cruzi tubulin delta chain 0.0011 0.0017 0.008
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0023
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0279 0.0812
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0678 0.0671
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0057 0.082 0.0814
Onchocerca volvulus 0.0036 0.046 0.1359
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0152 0.0145
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0599 0.1292
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0016 0.01 0.1104
Plasmodium falciparum tubulin delta chain, putative 0.0011 0.0017 0.008
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0022 0.0208 0.0201
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0043 0.0579 1
Echinococcus granulosus Mastin 0.0036 0.046 0.0453
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Leishmania major DNA polymerase eta, putative 0.0026 0.028 0.3321
Brugia malayi tubulin alpha-2 chain 0.0026 0.0279 0.059
Onchocerca volvulus 0.0025 0.0265 0.0769
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0308 0.0899
Plasmodium vivax tubulin alpha chain, putative 0.0026 0.0279 0.3517
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0023
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0016 0.01 0.027
Plasmodium vivax heat shock protein 90, putative 0.0022 0.0208 0.2588
Loa Loa (eye worm) hypothetical protein 0.0245 0.4159 0.9117
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Brugia malayi Trypsin family protein 0.0036 0.046 0.0988
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Schistosoma mansoni tubulin subunit alpha 0.0026 0.0279 0.0269
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Brugia malayi Cell death protein 3 precursor 0.0044 0.0599 0.1292
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0011 0.0011 0.0003
Loa Loa (eye worm) tubulin alpha 2 0.0015 0.0078 0.0171
Loa Loa (eye worm) hypothetical protein 0.0023 0.0217 0.0475
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0213 0.0467
Onchocerca volvulus Peroxidase homolog 0.0054 0.0769 0.229
Schistosoma mansoni loxhd1 0.002 0.0161 0.015
Loa Loa (eye worm) tubulin beta-1 chain 0.0049 0.0678 0.1486
Trypanosoma cruzi epsilon tubulin, putative 0.0026 0.0279 0.3517
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0161 0.0153
Echinococcus multilocularis caspase 8 0.0044 0.0599 0.0592
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Loa Loa (eye worm) hypothetical protein 0.0197 0.3305 0.7246
Schistosoma mansoni lamin 0.0022 0.0213 0.0203
Leishmania major delta tubulin, putative 0.0011 0.0017 0.0075
Brugia malayi Trypsin-like protease protein 5 0.0036 0.046 0.0988
Loa Loa (eye worm) hypothetical protein 0.0103 0.1637 0.3589
Brugia malayi Tubulin beta chain 0.0011 0.0017 0.0013
Schistosoma mansoni hypothetical protein 0.002 0.0161 0.015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.01 0.1171
Brugia malayi Pre-SET motif family protein 0.0025 0.0265 0.0559
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0043 0.0579 1
Leishmania major cytochrome p450-like protein 0.0015 0.0077 0.0825
Schistosoma mansoni heat shock protein 0.0054 0.0775 0.0765
Echinococcus granulosus tubulin subunit beta 0.0049 0.0678 0.0671
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Echinococcus granulosus enteropeptidase 0.0036 0.046 0.0453
Echinococcus multilocularis para nitrobenzyl esterase 0.0017 0.0123 0.0116
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0404 0.1188
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0544 0.1171
Trichomonas vaginalis rotamase, putative 0.0028 0.0308 0.0899
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0352
Trypanosoma cruzi Heat shock protein 83, putative 0.0054 0.0775 1
Brugia malayi hypothetical protein 0.0036 0.046 0.0988
Trypanosoma brucei beta tubulin 0.0049 0.0678 0.8736
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0011 0.0017 0.0018
Onchocerca volvulus 0.004 0.0527 0.156
Loa Loa (eye worm) tubulin alpha chain 0.0026 0.0279 0.0612
Schistosoma mansoni tubulin subunit gamma 0.0026 0.0279 0.0269
Schistosoma mansoni cpg binding protein 0.0025 0.0263 0.0253
Loa Loa (eye worm) tubulin alpha-3 chain 0.0011 0.0017 0.0037
Echinococcus granulosus tubulin alpha chain 0.0026 0.0279 0.0272
Schistosoma mansoni hypothetical protein 0.0023 0.0217 0.0206
Entamoeba histolytica heat shock protein 90, putative 0.0054 0.0775 1
Entamoeba histolytica tubulin alpha-1 chain 0.0026 0.0279 0.3517
Plasmodium vivax SET domain protein, putative 0.0025 0.0265 0.333
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0881 0.1912
Treponema pallidum quinoline 2-oxidoreductase 0.0014 0.0054 0.0768
Leishmania major metacaspase, putative 0.0044 0.0599 0.7261
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0161 0.0153
Brugia malayi Muscleblind-like protein 0.014 0.2288 0.5005
Echinococcus multilocularis dnaJ subfamily B 0.0341 0.5852 0.5849
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Trichomonas vaginalis tubulin, putative 0.0049 0.0678 0.2016
Giardia lamblia Heat shock protein HSP 90-alpha 0.0043 0.0579 0.7443
Trypanosoma brucei metacaspase MCA2 0.0044 0.0599 0.7697
Echinococcus granulosus acetylcholinesterase 0.0103 0.1637 0.1631
Trypanosoma cruzi metacaspase, putative 0.0044 0.0599 0.7697
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.1881 0.1875
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0011 0.0011 0.0003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0245 0.4159 0.9115
Plasmodium vivax tubulin epsilon chain, putative 0.0026 0.0279 0.3517
Echinococcus granulosus glycoprotein Antigen 5 0.0036 0.046 0.0453
Mycobacterium ulcerans aldehyde dehydrogenase 0.0057 0.082 1
Echinococcus granulosus tubulin alpha chain 0.0026 0.0279 0.0272
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0161 0.0153
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0013 0.0048 0.0041
Toxoplasma gondii alpha-tubulin I, putative 0.0026 0.0279 0.3318
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0078 0.0203
Trypanosoma brucei epsilon tubulin 0.0026 0.0279 0.3517
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0012 0.0014
Echinococcus granulosus transmembrane protease serine 3 0.0036 0.046 0.0453
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0279 0.0812
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Schistosoma mansoni rotamase 0.0028 0.0308 0.0298
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Entamoeba histolytica heat shock protein 90, putative 0.0054 0.0775 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Echinococcus multilocularis Tubulin alpha 1 chain 0.0026 0.0279 0.0272
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Loa Loa (eye worm) doublecortin family protein 0.002 0.0161 0.0352
Echinococcus multilocularis dna polymerase kappa 0.0016 0.01 0.0093
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Plasmodium falciparum tubulin beta chain 0.0049 0.0678 0.8736
Schistosoma mansoni aldehyde dehydrogenase 0.0057 0.082 0.0811
Schistosoma mansoni tubulin subunit alpha 0.0011 0.0017 0.0006
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0043 0.0579 0.7021
Echinococcus granulosus tubulin subunit TubB 0.0026 0.0279 0.0272
Schistosoma mansoni tubulin subunit beta 0.0049 0.0678 0.0668
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0599 0.7261
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.01 0.1171
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0161 0.0153
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0161 0.0153
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0265 0.0258
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0265 0.0255
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0678 0.2016
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0012 0.0014
Trichomonas vaginalis rotamase, putative 0.0027 0.0297 0.0864
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Echinococcus granulosus tumor protein p63 0.0282 0.4802 0.4798
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0017 0.0123 0.0113
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0265 0.3142
Trypanosoma brucei DNA polymerase eta, putative 0.0037 0.0476 0.6091
Brugia malayi Blistered cuticle protein 3 0.0054 0.0769 0.1666
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.01 0.0197
Echinococcus multilocularis tubulin alpha chain 0.0026 0.0279 0.0272
Schistosoma mansoni hypothetical protein 0.0041 0.0544 0.0534
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0011 0.0011 0.0003
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Brugia malayi Doublecortin family protein 0.002 0.0161 0.033
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0048 0.0467
Onchocerca volvulus 0.0036 0.046 0.1359
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Loa Loa (eye worm) hypothetical protein 0.0073 0.1116 0.2446
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0085 0.1321 0.3958
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Entamoeba histolytica deoxycytidyl transferase, putative 0.0016 0.01 0.1171
Schistosoma mansoni rab6-interacting 0.002 0.0161 0.015
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0016 0.01 0.0093
Schistosoma mansoni tubulin subunit alpha 0.0026 0.0279 0.0269
Echinococcus granulosus lamin dm0 0.0022 0.0213 0.0206
Schistosoma mansoni terminal deoxycytidyl transferase 0.0016 0.01 0.009
Loa Loa (eye worm) animal heme peroxidase 0.0054 0.0769 0.1685
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.01 0.1171
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0881 0.1931
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Echinococcus multilocularis tubulin alpha 1C chain 0.0026 0.0279 0.0272
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Mycobacterium ulcerans DNA polymerase IV 0.0016 0.01 0.1104
Trichomonas vaginalis tubulin alpha chain, putative 0.0015 0.0078 0.0203
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0013 0.0048 0.0467
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0048 0.0041
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0028 0.0308 0.0654
Plasmodium falciparum heat shock protein 90, putative 0.0022 0.0208 0.2588
Giardia lamblia Beta tubulin 0.0049 0.0678 0.8736
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0026 0.028 0.3321
Echinococcus granulosus alpha tubulin 0.0026 0.0279 0.0272
Echinococcus multilocularis tubulin gamma 1 chain 0.0026 0.0279 0.0272
Leishmania major gamma-tubulin 0.0026 0.0279 0.3318
Echinococcus granulosus cpg binding protein 0.0025 0.0263 0.0256
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0011 0.0017 0.0108
Brugia malayi beta-tubulin, identical 0.0049 0.0678 0.1467
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0599 0.0589
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0017 0.0123 0.1388
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0678 0.0671
Schistosoma mansoni rab6-interacting 0.002 0.0161 0.015
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0678 0.2016
Brugia malayi heat shock protein 90 0.0054 0.0775 0.1679
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0077 0.017
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0174 0.2896 0.6349
Echinococcus granulosus beta tubulin 0.0049 0.0678 0.0671
Echinococcus multilocularis Tubulin alpha 1 chain 0.0026 0.0279 0.0272
Treponema pallidum hypothetical protein 0.0011 0.0017 0.0108
Toxoplasma gondii beta-1 tubulin, putative 0.0049 0.0678 0.8241
Giardia lamblia Gamma tubulin 0.0026 0.0279 0.3517
Mycobacterium ulcerans aldehyde dehydrogenase 0.0057 0.082 1
Schistosoma mansoni heat shock protein 0.0054 0.0775 0.0765
Brugia malayi Tubulin gamma chain 0.0026 0.0279 0.059
Toxoplasma gondii histone lysine methyltransferase SET1 0.0046 0.0634 0.7703
Plasmodium falciparum endoplasmin, putative 0.0033 0.0404 0.5145
Echinococcus granulosus dna polymerase kappa 0.0016 0.01 0.0093
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.003 0.0346 0.0339
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Brugia malayi Tubulin alpha-2 chain 0.0026 0.0279 0.059
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Trypanosoma brucei beta tubulin 0.0026 0.0279 0.3517
Brugia malayi hypothetical protein 0.0054 0.0769 0.1666
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0678 0.0671
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0265 0.0255
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0017 0.0123 0.034
Trypanosoma brucei zeta tubulin, putative 0.0011 0.0017 0.008
Chlamydia trachomatis DNA gyrase subunit B 0.0011 0.0011 0.5
Brugia malayi Pre-SET motif family protein 0.0174 0.2896 0.6341
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Loa Loa (eye worm) tubulin gamma chain 0.0026 0.0279 0.0612
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Echinococcus multilocularis glycoprotein Antigen 5 0.0036 0.046 0.0453
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0027 0.0297 0.3743
Schistosoma mansoni tubulin subunit beta 0.0049 0.0678 0.0668
Plasmodium vivax tubulin beta chain, putative 0.0049 0.0678 0.8736
Schistosoma mansoni heat shock protein 0.0022 0.0208 0.0198
Echinococcus multilocularis BC026374 protein (S09 family) 0.0017 0.0123 0.0116
Leishmania major DNA polymerase eta, putative 0.0037 0.0476 0.5746
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0015 0.0078 0.0203
Schistosoma mansoni hypothetical protein 0.0019 0.0152 0.0142
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0028 0.0308 0.0676
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0678 0.0671
Schistosoma mansoni hypothetical protein 0.0023 0.0217 0.0206
Toxoplasma gondii Hsp90 domain-containing protein 0.0022 0.0208 0.2441
Echinococcus granulosus acetylcholinesterase 0.0103 0.1637 0.1631
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Trypanosoma brucei beta tubulin 0.0049 0.0678 0.8736
Loa Loa (eye worm) hypothetical protein 0.0022 0.0213 0.0467
Schistosoma mansoni hypothetical protein 0.003 0.0346 0.0336
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0678 0.0671
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Echinococcus multilocularis cpg binding protein 0.0025 0.0263 0.0256
Loa Loa (eye worm) tubulin beta chain 0.0049 0.0678 0.1486
Brugia malayi Carboxylesterase family protein 0.0017 0.0123 0.0247
Echinococcus multilocularis peroxisome assembly protein 26 0.0026 0.0279 0.0272
Toxoplasma gondii heat shock protein HSP90 0.0054 0.0775 0.9434
Leishmania major DNA polymerase kappa, putative 0.0016 0.01 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0599 0.1777
Schistosoma mansoni intermediate filament proteins 0.0022 0.0213 0.0203
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Loa Loa (eye worm) isocitrate dehydrogenase 0.0013 0.0048 0.0106
Brugia malayi Animal haem peroxidase family protein 0.0054 0.0769 0.1666
Echinococcus granulosus tubulin alpha chain 0.0026 0.0279 0.0272
Echinococcus granulosus caspase 8 0.0044 0.0599 0.0592
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Schistosoma mansoni hypothetical protein 0.0019 0.0152 0.0142
Schistosoma mansoni hypothetical protein 0.004 0.0527 0.0517
Brugia malayi Tubulin alpha chain 0.0011 0.0017 0.0013
Onchocerca volvulus Peroxidasin homolog 0.0054 0.0769 0.229
Trypanosoma brucei Metacaspase-4 0.0044 0.0599 0.7697
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0161 0.0153
Echinococcus granulosus peroxisome assembly protein 26 0.0026 0.0279 0.0272
Echinococcus granulosus tubulin alpha chain 0.0026 0.0279 0.0272
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Echinococcus granulosus heat shock protein 90 0.0043 0.0579 0.0572
Echinococcus granulosus tubulin alpha 3 chain 0.0026 0.0279 0.0272
Schistosoma mansoni tubulin subunit beta 0.0011 0.0017 0.0006
Echinococcus granulosus carboxylesterase 5A 0.0103 0.1637 0.1631
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0015 0.0077 0.0825
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0025 0.0261 0.3098
Loa Loa (eye worm) animal heme peroxidase 0.0054 0.0769 0.1685
Echinococcus multilocularis neuroligin 0.0017 0.0123 0.0116
Trypanosoma cruzi epsilon tubulin, putative 0.0026 0.0279 0.3517
Brugia malayi Carboxylesterase family protein 0.0017 0.0123 0.0247
Schistosoma mansoni caspase-7 (C14 family) 0.0044 0.0599 0.0589
Leishmania major epsilon tubulin, putative 0.0026 0.0279 0.3318
Echinococcus granulosus tubulin epsilon chain 0.0026 0.0279 0.0272
Mycobacterium ulcerans DNA polymerase IV 0.0016 0.01 0.1104
Loa Loa (eye worm) alpha-tubulin 0.0026 0.0279 0.0612
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Schistosoma mansoni hypothetical protein 0.0341 0.5852 0.5848
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0599 0.1777
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.0453
Onchocerca volvulus 0.0022 0.0213 0.0612
Trypanosoma cruzi alpha tubulin, putative 0.0026 0.0279 0.3517
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.027
Brugia malayi Tubulin beta chain 0.0015 0.0078 0.0148
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0029 0.0324 0.3864
Trichomonas vaginalis tubulin gamma chain, putative 0.0049 0.0678 0.2016
Mycobacterium tuberculosis Carboxylesterase LipT 0.0017 0.0123 0.1388
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0204 0.343 0.3426
Echinococcus granulosus Tubulin alpha 1 chain 0.0026 0.0279 0.0272
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0023
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0265 0.0258
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0015 0.0078 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0013 0.0048 0.0495
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0011 0.0011 0.0003
Echinococcus granulosus tubulin alpha 3 chain 0.0026 0.0279 0.0272
Schistosoma mansoni eyes absent homolog 0.0073 0.1116 0.1106
Toxoplasma gondii heat shock protein 90, putative 0.0054 0.0775 0.9434
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0057 0.082 0.0814
Trichomonas vaginalis tubulin epsilon chain, putative 0.0026 0.0279 0.0812
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Echinococcus granulosus tubulin alpha 0.0026 0.0279 0.0272
Schistosoma mansoni lamin 0.0022 0.0213 0.0203
Echinococcus granulosus Tubulin alpha 1 chain 0.0026 0.0279 0.0272
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Echinococcus granulosus tubulin gamma 1 chain 0.0026 0.0279 0.0272
Schistosoma mansoni tubulin subunit beta 0.0049 0.0678 0.0668
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0016
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0027 0.0297 0.3531
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0017 0.0123 0.0116
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.004 0.0525 0.6352
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Echinococcus multilocularis heat shock protein 0.0054 0.0775 0.0768
Schistosoma mansoni caspase-3 (C14 family) 0.0166 0.2745 0.2738
Loa Loa (eye worm) endoplasmin 0.0054 0.0775 0.1698
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0579 0.1718
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0036 0.046 0.0453
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0011 0.0011 0.5
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0775 0.2308
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0204 0.343 0.3426
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0036 0.046 0.0988
Plasmodium falciparum metacaspase-like protein 0.0044 0.0599 0.7697
Loa Loa (eye worm) carboxylesterase 0.0017 0.0123 0.027
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0678 0.0671
Trichomonas vaginalis tubulin epsilon chain, putative 0.0026 0.0279 0.0812
Brugia malayi Animal haem peroxidase family protein 0.0054 0.0769 0.1666
Schistosoma mansoni tubulin subunit delta 0.0011 0.0017 0.0006
Echinococcus multilocularis caspase 2 0.0044 0.0599 0.0592
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0579 0.1718
Onchocerca volvulus Peroxidasin homolog 0.0054 0.0769 0.229
Echinococcus multilocularis Mastin 0.0036 0.046 0.0453
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Schistosoma mansoni survival motor neuron protein 0.004 0.0527 0.0517
Brugia malayi Cytochrome P450 family protein 0.0015 0.0077 0.0147
Echinococcus multilocularis carboxylesterase 5A 0.0103 0.1637 0.1631
Trypanosoma brucei Heat shock protein 83, putative 0.0054 0.0775 1
Trichomonas vaginalis tubulin, putative 0.0015 0.0078 0.0203
Giardia lamblia Beta tubulin 0.0049 0.0678 0.8736
Trichomonas vaginalis tubulin alpha chain, putative 0.0049 0.0678 0.2016
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0017 0.0123 0.0116
Toxoplasma gondii beta-tubulin, putative 0.0049 0.0678 0.8241
Trichomonas vaginalis tubulin alpha chain, putative 0.0015 0.0078 0.0203
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.024 0.0232
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Echinococcus multilocularis endoplasmin 0.0043 0.0579 0.0572
Echinococcus granulosus tubulin beta 4A class IVa 0.0049 0.0678 0.0671
Plasmodium falciparum heat shock protein 90, putative 0.0022 0.0208 0.2588
Onchocerca volvulus Peroxidase homolog 0.0054 0.0769 0.229
Schistosoma mansoni polycystin 1-related 0.002 0.0161 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0599 0.1777
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0013 0.0048 0.0495
Toxoplasma gondii beta tubulin 0.0049 0.0678 0.8241
Echinococcus granulosus heat shock protein 90 0.0054 0.0775 0.0768
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0077 0.0875
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.004 0.0525 0.6352
Brugia malayi Animal haem peroxidase family protein 0.0054 0.0769 0.1666
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.01 0.1104
Mycobacterium leprae cell division protein FtsZ 0.0011 0.0017 0.0108
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0152 0.0312
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0016 0.01 0.0093
Loa Loa (eye worm) hypothetical protein 0.0041 0.0544 0.1192
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0013 0.0048 0.0041
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0265 0.0258
Brugia malayi isocitrate dehydrogenase 0.0013 0.0048 0.0083
Brugia malayi Tubulin alpha chain 0.0026 0.0279 0.059
Echinococcus multilocularis tubulin beta 1 chain 0.0049 0.0678 0.0671
Plasmodium vivax tubulin gamma chain, putative 0.0026 0.0279 0.3517
Loa Loa (eye worm) hypothetical protein 0.0025 0.0265 0.0581
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Echinococcus multilocularis survival motor neuron protein 1 0.0197 0.3305 0.33
Schistosoma mansoni gliotactin 0.0017 0.0123 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0077 0.017
Trypanosoma cruzi tubulin delta chain 0.0011 0.0017 0.008
Loa Loa (eye worm) blistered cuticle protein 3 0.0054 0.0769 0.1685
Onchocerca volvulus 0.002 0.0161 0.0453
Echinococcus multilocularis GPCR, family 2 0.0019 0.0152 0.0145
Toxoplasma gondii alpha tubulin TUBA1 0.0026 0.0279 0.3318
Echinococcus granulosus tubulin alpha chain 0.0026 0.0279 0.0272
Echinococcus granulosus expressed protein 0.0028 0.0308 0.0301
Mycobacterium ulcerans aldehyde dehydrogenase 0.0057 0.082 1
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.01 0.1171
Schistosoma mansoni caspase-7 (C14 family) 0.0166 0.2745 0.2738
Schistosoma mansoni hypothetical protein 0.0019 0.0152 0.0142
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0599 0.7697
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0599 0.7697
Schistosoma mansoni hypothetical protein 0.0019 0.0152 0.0142
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0048 0.0041
Echinococcus multilocularis tubulin subunit TubB 0.0026 0.0279 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.01 0.1171
Trichomonas vaginalis heat shock protein, putative 0.0022 0.0208 0.0597
Schistosoma mansoni tubulin subunit alpha 0.0026 0.0279 0.0269
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0022 0.0208 0.2588
Loa Loa (eye worm) hypothetical protein 0.014 0.2288 0.5017
Treponema pallidum hypothetical protein 0.0014 0.006 0.0868
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0048 0.0495
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0028 0.0062
Echinococcus multilocularis acetylcholinesterase 0.0103 0.1637 0.1631
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0279 0.0812
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0027 0.0297 0.3743
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.0775 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0049 0.0678 0.0671
Schistosoma mansoni peroxidasin 0.0054 0.0769 0.0759
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Trypanosoma brucei alpha tubulin 0.0026 0.0279 0.3517
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Brugia malayi Trypsin family protein 0.0036 0.046 0.0988
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0016 0.0103 0.1137
Schistosoma mansoni peroxidasin 0.0054 0.0769 0.0759
Onchocerca volvulus 0.002 0.0161 0.0453
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Mycobacterium ulcerans cell division protein FtsZ 0.0011 0.0017 0.0075
Echinococcus multilocularis lamin 0.0022 0.0213 0.0206
Echinococcus multilocularis tumor protein p63 0.0282 0.4802 0.4798
Treponema pallidum cell division protein FtsZ 0.0011 0.0017 0.0108
Echinococcus granulosus dnaJ subfamily B 0.0341 0.5852 0.5849
Loa Loa (eye worm) beta-tubulin 0.0049 0.0678 0.1486
Trichomonas vaginalis tubulin gamma chain, putative 0.0026 0.0279 0.0812
Schistosoma mansoni alpha tubulin 0.0026 0.0279 0.0269
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1116 0.2446
Onchocerca volvulus 0.0054 0.0769 0.229
Schistosoma mansoni DNA polymerase eta 0.0037 0.0476 0.0466
Onchocerca volvulus 0.0036 0.046 0.1359
Schistosoma mansoni tubulin subunit epsilon 0.0026 0.0279 0.0269
Brugia malayi hypothetical protein 0.002 0.0161 0.033
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0013 0.0048 0.0038
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0152 0.0334
Onchocerca volvulus 0.0017 0.0123 0.034
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0279 0.0812
Echinococcus multilocularis caspase 3 0.0121 0.1962 0.1956
Loa Loa (eye worm) hypothetical protein 0.0015 0.0078 0.0171
Echinococcus multilocularis hypothetical protein 0.0026 0.0279 0.0272
Loa Loa (eye worm) carboxylesterase 0.0017 0.0123 0.027
Trypanosoma cruzi tubulin gamma chain 0.0026 0.0279 0.3517
Loa Loa (eye worm) tubulin alpha chain 0.0026 0.0279 0.0612
Schistosoma mansoni aldehyde dehydrogenase 0.0057 0.082 0.0811
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0599 0.7697
Plasmodium vivax heat shock protein 86, putative 0.0054 0.0775 1
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0166 0.2745 0.274
Schistosoma mansoni acetylcholinesterase 0.0017 0.0123 0.0113
Loa Loa (eye worm) heat shock protein 75 0.0022 0.0208 0.0457
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0678 0.0671
Echinococcus granulosus caspase 0.0166 0.2745 0.274
Onchocerca volvulus 0.0036 0.046 0.1359
Schistosoma mansoni hypothetical protein 0.0036 0.046 0.045
Brugia malayi hypothetical protein 0.0073 0.1116 0.2428
Echinococcus multilocularis tubulin alpha chain 0.0026 0.0279 0.0272
Onchocerca volvulus 0.0054 0.0769 0.229
Echinococcus granulosus endoplasmin 0.0043 0.0579 0.0572
Echinococcus granulosus tubulin alpha 1C chain 0.0026 0.0279 0.0272
Trichomonas vaginalis tubulin gamma chain, putative 0.0026 0.0279 0.0812
Schistosoma mansoni cellular tumor antigen P53 0.0041 0.0545 0.0535
Leishmania major heat shock protein, putative 0.0022 0.0208 0.2441
Plasmodium vivax delta tubulin, putative 0.0011 0.0017 0.008
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0036 0.046 0.0453
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0352
Mycobacterium ulcerans hypothetical protein 0.0036 0.046 0.5552
Trypanosoma brucei tubulin gamma chain 0.0026 0.0279 0.3517
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0678 0.1486
Echinococcus granulosus tubulin alpha 1C chain 0.0026 0.0279 0.0272
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0011 0.0017 0.0075
Trypanosoma brucei metacaspase 0.0044 0.0599 0.7697
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0678 0.1486
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0213 0.0445
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Schistosoma mansoni BC026374 protein (S09 family) 0.0017 0.0123 0.0113
Onchocerca volvulus 0.0024 0.0239 0.069
Schistosoma mansoni cpg binding protein 0.0025 0.0263 0.0253
Trichomonas vaginalis tubulin, putative 0.0015 0.0078 0.0203
Loa Loa (eye worm) tubulin alpha 2 0.0015 0.0078 0.0171
Brugia malayi tubulin alpha chain - mouse 0.0026 0.0279 0.059
Brugia malayi CXXC zinc finger family protein 0.0024 0.0239 0.0502
Trypanosoma cruzi metacaspase, putative 0.0044 0.0599 0.7697
Trypanosoma cruzi metacaspase, putative 0.0044 0.0599 0.7697
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0016 0.0103 0.1137
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0036 0.046 0.1009
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0017 0.0123 0.0113
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0036 0.046 0.045
Trypanosoma brucei heat shock protein 84, putative 0.0022 0.0208 0.2588
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0404 0.1188
Giardia lamblia Delta tubulin 0.0011 0.0017 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0036 0.046 0.045
Echinococcus granulosus muscleblind protein 0.014 0.2288 0.2283
Entamoeba histolytica tubulin alpha chain, putative 0.0026 0.0279 0.3517
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0476 0.6091
Loa Loa (eye worm) hypothetical protein 0.0103 0.1637 0.3589
Echinococcus granulosus protein quaking 0.0023 0.0217 0.021
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0161 0.1963
Echinococcus multilocularis tubulin subunit beta 0.0049 0.0678 0.0671
Trypanosoma brucei epsilon tubulin 0.0026 0.0279 0.3517
Trypanosoma brucei alpha tubulin 0.0026 0.0279 0.3517
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Loa Loa (eye worm) animal heme peroxidase 0.0054 0.0769 0.1685
Trypanosoma brucei unspecified product 0.0011 0.0012 0.0014
Echinococcus multilocularis heat shock protein 90 0.0054 0.0775 0.0768
Brugia malayi Endoplasmin precursor 0.0054 0.0775 0.1679
Toxoplasma gondii aldehyde dehydrogenase 0.0057 0.082 1
Schistosoma mansoni transcription factor LCR-F1 0.003 0.0346 0.0336
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0022 0.0208 0.0201
Echinococcus granulosus tubulin delta chain 0.0011 0.0017 0.0009
Plasmodium vivax heat shock protein, putative 0.0022 0.0208 0.2588
Echinococcus multilocularis Tubulin alpha 1 chain 0.0026 0.0279 0.0272
Mycobacterium tuberculosis Cell division protein FtsZ 0.0011 0.0017 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Echinococcus multilocularis enteropeptidase 0.0036 0.046 0.0453
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0152 0.0145
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Echinococcus granulosus BC026374 protein S09 family 0.0017 0.0123 0.0116
Echinococcus multilocularis acetylcholinesterase 0.0103 0.1637 0.1631
Echinococcus multilocularis microtubule associated protein 2 0.0575 1 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0161 0.1963
Loa Loa (eye worm) heat shock protein 90 0.0054 0.0775 0.1698
Echinococcus multilocularis tubulin alpha 3 chain 0.0026 0.0279 0.0272
Giardia lamblia Alpha-tubulin 0.0026 0.0279 0.3517
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0599 0.7261
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Trypanosoma brucei beta tubulin 0.0049 0.0678 0.8736
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0678 0.0671
Loa Loa (eye worm) trypsin family protein 0.0036 0.046 0.1009
Trichomonas vaginalis set domain proteins, putative 0.0198 0.332 1
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0678 0.0671
Plasmodium vivax tubulin alpha chain, putative 0.0026 0.0279 0.3517
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Mycobacterium ulcerans heat shock protein 90 0.0043 0.0579 0.7021
Echinococcus granulosus para nitrobenzyl esterase 0.0017 0.0123 0.0116
Toxoplasma gondii peptidylprolyl isomerase 0.0027 0.0297 0.3531
Onchocerca volvulus 0.0017 0.0123 0.034
Onchocerca volvulus 0.0017 0.0123 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0018
Trichomonas vaginalis tubulin epsilon chain, putative 0.0011 0.0017 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Brugia malayi Carboxylesterase family protein 0.0103 0.1637 0.3574
Onchocerca volvulus 0.0198 0.332 1
Plasmodium falciparum alpha tubulin 1 0.0026 0.0279 0.3517
Leishmania major alpha tubulin 0.0026 0.0279 0.3318
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0048 0.0467
Trypanosoma brucei alpha tubulin, putative 0.0015 0.0078 0.088
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Brugia malayi alpha-tubulin 0.0026 0.0279 0.059
Trypanosoma cruzi zeta tubulin, putative 0.0011 0.0017 0.008
Brugia malayi Peroxidasin 0.0054 0.0769 0.1666
Echinococcus granulosus survival motor neuron protein 1 0.0197 0.3305 0.33
Echinococcus multilocularis transmembrane protease serine 3 0.0036 0.046 0.0453
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0476 0.1023
Brugia malayi hypothetical protein 0.002 0.0161 0.033
Treponema pallidum heat shock protein 90 0.0043 0.0579 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0015 0.0078 0.0203
Schistosoma mansoni cpg binding protein 0.0024 0.0239 0.0229
Echinococcus granulosus heat shock protein 0.0054 0.0775 0.0768
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Onchocerca volvulus Dual oxidase homolog 0.0054 0.0769 0.229
Schistosoma mansoni tubulin subunit beta 0.0049 0.0678 0.0668
Echinococcus multilocularis tubulin alpha chain 0.0026 0.0279 0.0272
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Schistosoma mansoni alpha tubulin 0.0026 0.0279 0.0269
Trypanosoma cruzi heat shock protein 90, putative 0.0043 0.0579 0.7443
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0057 0.082 1
Trypanosoma cruzi zeta tubulin, putative 0.0011 0.0017 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0044 0.0599 0.1312
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0678 0.0671
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.01 0.009
Loa Loa (eye worm) acetylcholinesterase 1 0.0103 0.1637 0.3589
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0037
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0056 0.0812 0.9901
Trypanosoma brucei heat shock protein 90, putative 0.0054 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0206 0.0451
Echinococcus granulosus beta tubulin 0.0049 0.0678 0.0671
Plasmodium falciparum alpha tubulin 2 0.0026 0.0279 0.3517
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0017 0.0123 0.1388
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Loa Loa (eye worm) tumor suppressor 0.0268 0.4562 1
Brugia malayi hypothetical protein 0.0197 0.3305 0.724
Loa Loa (eye worm) hypothetical protein 0.0054 0.0769 0.1685
Brugia malayi Animal haem peroxidase family protein 0.0054 0.0769 0.1666
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.1881 0.1875
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Schistosoma mansoni hypothetical protein 0.0036 0.046 0.045
Brugia malayi Trypsin family protein 0.0036 0.046 0.0988
Trypanosoma brucei heat shock protein, putative 0.0054 0.0775 1
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.01 0.1171
Toxoplasma gondii heat shock protein 75, putative 0.0022 0.0208 0.2441
Loa Loa (eye worm) carboxylesterase 0.0103 0.1637 0.3589
Echinococcus multilocularis beta tubulin 0.0049 0.0678 0.0671
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0579 0.1718
Entamoeba histolytica tubulin family protein 0.0049 0.0678 0.8736
Trypanosoma brucei alpha tubulin 0.0026 0.0279 0.3517
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0599 0.7261
Schistosoma mansoni tubulin subunit beta 0.0049 0.0678 0.0668
Trichomonas vaginalis tubulin, putative 0.0011 0.0017 0.0018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0103 0.1637 0.1628
Onchocerca volvulus 0.0036 0.046 0.1359
Loa Loa (eye worm) CXXC zinc finger family protein 0.0024 0.0239 0.0524
Echinococcus multilocularis RUN 0.002 0.0161 0.0153
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0048 0.0467
Entamoeba histolytica hypothetical protein 0.003 0.0346 0.4392
Brugia malayi Temporarily assigned gene name protein 44 0.0023 0.0217 0.0453
Schistosoma mansoni microtubule-associated protein tau 0.0575 1 1
Trypanosoma brucei unspecified product 0.0011 0.0012 0.0014
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0026 0.0279 0.3318
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.0775 1
Schistosoma mansoni tubulin subunit beta 0.0049 0.0678 0.0668
Trichomonas vaginalis spcc417.12 protein, putative 0.0017 0.0123 0.034
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0027 0.0297 0.3743
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Leishmania major heat shock protein 83-1 0.0054 0.0775 0.9434
Schistosoma mansoni cercarial elastase (S01 family) 0.0036 0.046 0.045
Trichomonas vaginalis tubulin beta chain, putative 0.0049 0.0678 0.2016
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0077 0.0875
Echinococcus multilocularis tubulin delta chain 0.0011 0.0017 0.0009
Onchocerca volvulus 0.0041 0.0545 0.1615
Loa Loa (eye worm) TOPoisomerase family member 0.0011 0.0011 0.0023
Echinococcus multilocularis peroxidasin 0.0054 0.0769 0.0762
Plasmodium falciparum metacaspase 1 0.0044 0.0599 0.7697
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0599 0.1777
Brugia malayi Hsp90 protein 0.0022 0.0208 0.0434
Echinococcus multilocularis tubulin alpha chain 0.0026 0.0279 0.0272
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0166 0.2745 0.274
Trypanosoma brucei metacaspase MCA3 0.0044 0.0599 0.7697
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0077 0.0875
Loa Loa (eye worm) tubulin beta-2A chain 0.0049 0.0678 0.1486
Schistosoma mansoni alpha tubulin 0.0026 0.0279 0.0269
Leishmania major beta tubulin 0.0049 0.0678 0.8241
Plasmodium falciparum tubulin epsilon chain, putative 0.0026 0.0279 0.3517
Leishmania major zeta tubulin, putative 0.0011 0.0017 0.0075
Schistosoma mansoni endoplasmin 0.0054 0.0775 0.0765
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.01 0.1171
Brugia malayi hypothetical protein 0.0023 0.0217 0.0453
Echinococcus multilocularis beta tubulin 0.0049 0.0678 0.0671
Loa Loa (eye worm) hypothetical protein 0.014 0.2288 0.5017
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0152 0.0312
Brugia malayi hypothetical protein 0.0017 0.0123 0.0247
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.004 0.0527 0.1135
Brugia malayi Cell division protein ftsZ 0.0011 0.0017 0.0013
Loa Loa (eye worm) alpha-tubulin 0.0026 0.0279 0.0612
Brugia malayi tumor suppressor. 0.0268 0.4562 1
Trypanosoma brucei tubulin delta chain 0.0011 0.0017 0.008
Trypanosoma brucei beta tubulin 0.0049 0.0678 0.8736
Chlamydia trachomatis DNA gyrase subunit B 0.0011 0.0011 0.5
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0599 0.1777
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0265 0.0255
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0015 0.0078 0.0203

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 16 nM Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand ChEMBL. 12951129
Ki (binding) = 16 nM Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand ChEMBL. 12951129

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.