Detailed information for compound 233937

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 320.299 | Formula: C18H12N2O4
  • H donors: 2 H acceptors: 4 LogP: 2.64 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1/C(=C\c2ccc(cc2)n2cncc2)/Oc2c1ccc(c2O)O
  • InChi: 1S/C18H12N2O4/c21-14-6-5-13-16(22)15(24-18(13)17(14)23)9-11-1-3-12(4-2-11)20-8-7-19-10-20/h1-10,21,23H/b15-9+
  • InChiKey: FCUFNEGRJQGOKR-OQLLNIDSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Chorismate synthase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium vivax chorismate synthase Get druggable targets OG5_128304 All targets in OG5_128304
Plasmodium yoelii chorismate synthase, putative Get druggable targets OG5_128304 All targets in OG5_128304
Plasmodium berghei chorismate synthase, putative Get druggable targets OG5_128304 All targets in OG5_128304
Candida albicans Chorismate synthase Get druggable targets OG5_128304 All targets in OG5_128304
Candida albicans chorismate synthase Get druggable targets OG5_128304 All targets in OG5_128304
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) Get druggable targets OG5_128304 All targets in OG5_128304
Neospora caninum Chorismate synthase (EC 4.2.3.5), related Get druggable targets OG5_128304 All targets in OG5_128304
Mycobacterium ulcerans chorismate synthase Get druggable targets OG5_128304 All targets in OG5_128304
Toxoplasma gondii chorismate synthase, putative Get druggable targets OG5_128304 All targets in OG5_128304
Plasmodium falciparum chorismate synthase Get druggable targets OG5_128304 All targets in OG5_128304
Plasmodium knowlesi chorismate synthase, putative Get druggable targets OG5_128304 All targets in OG5_128304
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). Get druggable targets OG5_128304 All targets in OG5_128304
Chlamydia trachomatis chorismate synthase Get druggable targets OG5_128304 All targets in OG5_128304
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis expressed conserved protein 0.0102 0.0639 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0263 0.1211
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Toxoplasma gondii lysine-tRNA ligase 0.0071 0.0424 0.066
Entamoeba histolytica protein kinase, putative 0.0046 0.0246 0.3589
Brugia malayi neuroendocrine convertase 1 precursor 0.0013 0.0013 0.0062
Echinococcus multilocularis Niemann Pick C1 protein 0.0108 0.0685 0.0685
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Echinococcus multilocularis Small ubiquitin modifier 2 0.0034 0.016 0.016
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0048 0.0209
Entamoeba histolytica hypothetical protein 0.0027 0.0114 0.1659
Echinococcus granulosus ubiquitin 0.0012 0.0005 0.0005
Plasmodium vivax lysine--tRNA ligase, putative 0.0071 0.0424 0.0434
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0048 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0114 0.0502
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0071 0.0071
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0098 0.0613 0.2822
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0062 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0268 0.1234
Echinococcus granulosus Niemann Pick C1 protein 0.0108 0.0685 0.0685
Entamoeba histolytica protein kinase, putative 0.0046 0.0246 0.3589
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0062 0.0231
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0048 0.0037
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0098 0.0613 0.2674
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.0023 0.0149
Echinococcus multilocularis membrane bound transcription factor site 1 0.0013 0.0013 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0023 0.0107
Plasmodium vivax proline--tRNA ligase, putative 0.0111 0.0708 0.0735
Loa Loa (eye worm) subtilase 0.0013 0.0013 0.0062
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0098 0.0613 0.2822
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.0312
Mycobacterium ulcerans hypothetical protein 0.0049 0.0268 0.1775
Toxoplasma gondii sugar transporter ST1 0.0045 0.0238 0.0364
Schistosoma mansoni microtubule-associated protein tau 0.1426 1 1
Plasmodium falciparum mitogen-activated protein kinase 2 0.0515 0.3559 0.3749
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0013 0.0059
Loa Loa (eye worm) hypothetical protein 0.0198 0.1322 0.609
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.1031 0.4518
Loa Loa (eye worm) fli-1 protein 0.0213 0.1427 0.6571
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.0312
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0013 0.0013 0.0038
Loa Loa (eye worm) major facilitator superfamily transporter 0.0045 0.0238 0.1096
Schistosoma mansoni hypothetical protein 0.0045 0.0238 0.0238
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0045 0.0238 1
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.154 0.154
Echinococcus multilocularis neuroendocrine convertase 2 0.0013 0.0013 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0268 0.3853
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0071 0.0071
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0098 0.0613 0.0962
Brugia malayi Latrophilin receptor protein 2 0.0015 0.003 0.0136
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0111 0.0708 0.3098
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0071 0.0273
Mycobacterium ulcerans sugar transporter 0.0045 0.0238 0.1566
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Entamoeba histolytica hypothetical protein 0.0039 0.0201 0.2921
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0033 0.0105
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0023 0.0099
Schistosoma mansoni site-1 peptidase (S08 family) 0.0013 0.0013 0.0013
Brugia malayi Niemann-Pick C1 protein precursor 0.0108 0.0685 0.3157
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0033 0.0151
Leishmania major glucose transporter, lmgt1 0.0099 0.0619 0.2691
Schistosoma mansoni sugar transporter 0.0045 0.0238 0.0238
Brugia malayi Sugar transporter family protein 0.0318 0.2171 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0071 0.0257
Brugia malayi major facilitator superfamily protein 0.0045 0.0238 0.1096
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0095 0.0596 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0246 0.0246
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0011 0.0001 0.0001
Leishmania major myo-inositol/proton symporter (MIT) 0.0045 0.0238 0.0997
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.006 0.0348 0.5068
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0013 0.0013 0.0013
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0114 0.0167
Echinococcus multilocularis protein patched 0.0046 0.0249 0.0249
Brugia malayi major facilitator superfamily protein 0.0045 0.0238 0.1096
Trichomonas vaginalis myo-inositol transporter, putative 0.0045 0.0238 0.1093
Leishmania major hypothetical protein, conserved 0.0016 0.0033 0.0089
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0023 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0238 0.1093
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0198 0.1322 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0071 0.0424 0.2862
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0613 0.0613
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.089 0.6213 0.6213
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0023 0.0099
Schistosoma mansoni ets-related 0.0213 0.1427 0.1427
Onchocerca volvulus 0.0045 0.0238 0.1799
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0062 0.0285
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0023 0.0044
Onchocerca volvulus 0.0045 0.0238 0.1799
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0013 0.0059
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0062 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0013 0.0013 0.0056
Echinococcus granulosus solute carrier family 22 0.0045 0.0238 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.001 0.0042
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0023 0.0023
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0048 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0417 0.0417
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0071 0.0312
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0023 0.0044
Trypanosoma cruzi glucose transporter, putative 0.0045 0.0238 0.1047
Mycobacterium ulcerans hypothetical protein 0.0175 0.1156 0.7971
Echinococcus multilocularis 0.0013 0.0013 0.0013
Trichomonas vaginalis ubiquitin, putative 0.0012 0.0005 0.0019
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0417 0.1922
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0249 0.0249
Leishmania major DNA polymerase eta, putative 0.0021 0.0071 0.0257
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.1031 0.4549
Schistosoma mansoni site-1 peptidase (S08 family) 0.0013 0.0013 0.0013
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Loa Loa (eye worm) oxidoreductase 0.0014 0.0023 0.0107
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0019
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0023 0.0023
Onchocerca volvulus 0.0045 0.0238 0.1799
Schistosoma mansoni hypothetical protein 0.0318 0.2171 0.2171
Plasmodium falciparum subtilisin-like protease 1 0.0186 0.1236 0.1293
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0071 0.0071
Schistosoma mansoni lysyl-tRNA synthetase 0.0071 0.0424 0.0424
Brugia malayi lysyl-tRNA synthetase 0.0071 0.0424 0.1952
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Echinococcus multilocularis solute carrier family 22 0.0045 0.0238 0.0238
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0046 0.0246 0.0246
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Echinococcus multilocularis ubiquitin 0.0012 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0108 0.0685 1
Onchocerca volvulus 0.0045 0.0238 0.1799
Echinococcus granulosus Sugar transporter ERD6 protein 0.0045 0.0238 0.0238
Chlamydia trachomatis chorismate synthase 0.0216 0.1447 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0268 0.1775
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.1149
Schistosoma mansoni hypothetical protein 0.0015 0.003 0.003
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.154 0.154
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.0312
Plasmodium falciparum calcium-dependent protein kinase 2 0.0098 0.0613 0.0634
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0062 0.0083
Toxoplasma gondii subtilisin SUB7 0.0013 0.0013 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0013 0.0059
Onchocerca volvulus 0.0045 0.0238 0.1799
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Schistosoma mansoni hypothetical protein 0.0015 0.003 0.003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0263 0.1211
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0062 0.0285
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0268 0.3901
Leishmania major glucose transporter, lmgt2 0.0099 0.0619 0.2691
Echinococcus granulosus solute carrier family 22 0.0045 0.0238 0.0238
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0111 0.0708 0.3125
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0238 0.1096
Echinococcus granulosus calcium dependent protein kinase 0.0091 0.0568 0.0568
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0071 0.0424 0.1836
Toxoplasma gondii subtilisin SUB2 0.0013 0.0013 0.0006
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0033 0.0303
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0071 0.0424 0.6214
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0619 0.285
Plasmodium vivax hexose transporter 0.0318 0.2171 0.2281
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0071 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0166 0.137
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0045 0.0238 0.1566
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0062 0.0062
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0013 0.0013 0.0016
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0049 0.0268 0.1234
Schistosoma mansoni gabp alpha 0.007 0.0417 0.0417
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0071 0.0404
Plasmodium vivax calcium-dependent protein kinase, putative 0.0098 0.0613 0.0634
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0014 0.0023 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.016 0.0732
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0062 0.027
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0023 0.0123
Giardia lamblia Sugar-proton symporter 0.0045 0.0238 0.346
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.0023 0.0068
Trichomonas vaginalis sugar transport protein, putative 0.0045 0.0238 0.1093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0114 0.0523
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trypanosoma brucei subtilisin peptidase 0.0013 0.0013 0.0016
Onchocerca volvulus 0.0047 0.0252 0.1904
Onchocerca volvulus 0.0012 0.0005 0.0037
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0023 0.0099
Brugia malayi hypothetical protein 0.0045 0.0238 0.1096
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0062 0.0893
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0025 0.0067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0071 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0048 0.0048
Toxoplasma gondii chorismate synthase, putative 0.0216 0.1447 0.2292
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Toxoplasma gondii subtilisin SUB12 0.0013 0.0013 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0268 0.1234
Plasmodium falciparum protein kinase 6 0.1351 0.9472 1
Echinococcus granulosus neuroendocrine convertase 2 0.0013 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Brugia malayi celfurPC protein 0.0013 0.0013 0.0062
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0062 0.0285
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0023 0.0022
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0023 0.0123
Loa Loa (eye worm) major facilitator superfamily transporter 0.0045 0.0238 0.1096
Echinococcus granulosus membrane bound transcription factor site 1 0.0013 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Schistosoma mansoni lysyl-tRNA synthetase 0.0071 0.0424 0.0424
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0048 0.017
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0023 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0023 0.0022
Giardia lamblia DINP protein human, muc B family 0.0021 0.0071 0.0423
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.0023 0.0068
Plasmodium falciparum lysine--tRNA ligase 0.0071 0.0424 0.0434
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0023 0.0123
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0016 0.0033 0.0038
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Leishmania major protein kinase, putative 0.0098 0.0613 0.2662
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0155 0.0713
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0095 0.0596 0.2747
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Schistosoma mansoni glucose transport protein 0.0318 0.2171 0.2171
Entamoeba histolytica hypothetical protein 0.0039 0.0201 0.2921
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0251 0.1106
Loa Loa (eye worm) hypothetical protein 0.0108 0.0685 0.3157
Toxoplasma gondii facilitative glucose transporter GT1 0.0318 0.2171 0.3447
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0023 0.0107
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.001 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0238 0.1093
Loa Loa (eye worm) hypothetical protein 0.0078 0.047 0.2164
Onchocerca volvulus 0.0045 0.0238 0.1799
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Leishmania major hypothetical protein, conserved 0.0016 0.0033 0.0089
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.006 0.0348 0.2955
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0048 0.0222
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0045 0.0238 0.0238
Schistosoma mansoni fkbp-rapamycin associated protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0098 0.0613 0.2822
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Loa Loa (eye worm) hypothetical protein 0.0229 0.154 0.7095
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0268 0.2256
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Entamoeba histolytica hypothetical protein 0.0012 0.0005 0.006
Trypanosoma brucei glucose transporter 1E 0.0099 0.0619 0.2703
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.0023 0.0068
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Loa Loa (eye worm) hypothetical protein 0.0037 0.018 0.083
Giardia lamblia GTOR 0.002 0.0062 0.0251
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0045 0.0238 0.1995
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0023 0.0123
Mycobacterium ulcerans hypothetical protein 0.0016 0.0033 0.0139
Onchocerca volvulus 0.0045 0.0238 0.1799
Plasmodium falciparum chorismate synthase 0.0216 0.1447 0.1515
Leishmania major glucose transporter, lmgt3 0.0099 0.0619 0.2691
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Schistosoma mansoni glucose transport protein 0.0318 0.2171 0.2171
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0095 0.0596 0.87
Onchocerca volvulus 0.0045 0.0238 0.1799
Schistosoma mansoni hypothetical protein 0.0047 0.0252 0.0252
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0023 0.0123
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Leishmania major DNA polymerase kappa, putative 0.0021 0.0071 0.0257
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0062 0.0231
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0023 0.0068
Onchocerca volvulus 0.0014 0.0023 0.0176
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0071 0.0424 0.2862
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0268 0.1775
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0034 0.016 0.1022
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0238 0.1096
Schistosoma mansoni sugar transporter 0.0045 0.0238 0.0238
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0071 0.0328
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Plasmodium falciparum protein kinase 7 0.09 0.628 0.6625
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0251 0.1106
Brugia malayi endoprotease bli-4 precursor 0.0013 0.0013 0.0062
Trypanosoma brucei THT1 - hexose transporter, putative 0.0099 0.0619 0.2703
Trichomonas vaginalis sugar transporter, putative 0.0099 0.0619 0.285
Onchocerca volvulus 0.0014 0.0023 0.0176
Schistosoma mansoni sugar transporter 0.0045 0.0238 0.0238
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0033 0.0144
Echinococcus multilocularis Niemann Pick C1 protein 0.0154 0.1013 0.1013
Entamoeba histolytica hypothetical protein 0.0039 0.0201 0.2921
Giardia lamblia Sentrin 0.0034 0.016 0.2033
Giardia lamblia Lysyl-tRNA synthetase 0.0071 0.0424 0.6849
Trypanosoma cruzi hexose transporter, putative 0.0045 0.0238 0.1047
Echinococcus multilocularis synaptic vesicle 2 protein 0.0045 0.0238 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Brugia malayi hypothetical protein 0.0045 0.0238 0.1096
Brugia malayi proprotein convertase 2 0.0013 0.0013 0.0062
Onchocerca volvulus 0.0049 0.0268 0.2026
Plasmodium falciparum hexose transporter 0.0318 0.2171 0.2281
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0251 0.1106
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0062 0.0215
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0023 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0249 0.1146
Brugia malayi Subtilase family protein 0.0013 0.0013 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.018 0.083
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.1031 0.4527
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0023 0.0099
Echinococcus granulosus dna polymerase kappa 0.0021 0.0071 0.0071
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Echinococcus multilocularis Furin 1 0.0013 0.0013 0.0013
Echinococcus granulosus synaptic vesicle 2 protein 0.0045 0.0238 0.0238
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0268 0.1234
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Echinococcus granulosus Furin 1 0.0013 0.0013 0.0013
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0332 0.2265 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0013 0.0059
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.0062 0.027
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0048 0.0037
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0033 0.0212
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0023 0.0104
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.018 0.083
Echinococcus granulosus Niemann Pick C1 protein 0.0154 0.1013 0.1013
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0062 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0023 0.0107
Toxoplasma gondii subtilisin SUB1 0.0186 0.1236 0.1956
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0023 0.0107
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0071 0.0328
Onchocerca volvulus 0.0045 0.0238 0.1799
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0023 0.0107
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0098 0.0613 0.0634
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0268 0.3853
Schistosoma mansoni hypothetical protein 0.0045 0.0238 0.0238
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0013 0.0013 0.0056
Trypanosoma brucei glucose transporter 2A 0.0099 0.0619 0.2703
Brugia malayi Cam kinase protein 1 0.0098 0.0613 0.2822
Loa Loa (eye worm) hypothetical protein 0.0037 0.018 0.083
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Loa Loa (eye worm) SMO-1 protein 0.0034 0.016 0.0735
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0048 0.0526
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0268 0.3901
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0114 0.0527
Plasmodium falciparum calcium-dependent protein kinase 3 0.0098 0.0613 0.0634
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.0062 0.0215
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0025 0.0067
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0062 0.0062
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0014 0.0023 0.0068
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0023 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0033 0.0144
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0107
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0034 0.016 0.016
Schistosoma mansoni protein kinase 0.0098 0.0613 0.0613
Trypanosoma brucei THT1 - hexose transporter, putative 0.0099 0.0619 0.2703
Echinococcus multilocularis GPCR, family 2 0.0015 0.003 0.003
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0238 0.1093
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trypanosoma brucei THT1 - hexose transporter, putative 0.0099 0.0619 0.2703
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0268 0.113
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0071 0.0325
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0318 0.2171 0.2171
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Entamoeba histolytica protein kinase, putative 0.0098 0.0613 0.8937
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0013 0.0013 0.0013
Echinococcus multilocularis calcium dependent protein kinase 0.0091 0.0568 0.0568
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0048 0.0048
Trypanosoma cruzi small ubiquitin protein, putative 0.0034 0.016 0.0702
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.003 0.003
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0046 0.0246 0.0246
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0098 0.0613 0.0962
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0111 0.0708 0.3086
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.2265 1
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0048 0.0048
Toxoplasma gondii sugar transporter ST2 0.0045 0.0238 0.0364
Toxoplasma gondii subtilisin SUB9 0.0013 0.0013 0.0006
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0111 0.0708 0.1114
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0048 0.0209
Schistosoma mansoni hypothetical protein 0.0039 0.0201 0.0201
Trypanosoma cruzi hexose transporter, putative 0.0099 0.0619 0.2732
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0062 0.027
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.018 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Toxoplasma gondii small ubiquitin family modifier, putative 0.0034 0.016 0.0239
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0095 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0037 0.018 0.083
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0062 0.0062
Echinococcus granulosus solute carrier family 22 0.0045 0.0238 0.0238
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0023 0.0123
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.006 0.0348 0.2955
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0071 0.0273
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0018 0.0048 0.0692
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0071 0.0542
Echinococcus multilocularis General substrate transporter 0.0274 0.1855 0.1855
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Onchocerca volvulus 0.0013 0.0013 0.0102
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0046 0.0246 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0166 0.137
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0045 0.0238 0.1566
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0013 0.0013 0.0013
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0048 0.017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Leishmania major mitochondrial DNA polymerase beta 0.0332 0.2265 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0268 0.1234
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0071 0.0542
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0114 0.0114
Toxoplasma gondii sugar transporter ST3 0.0045 0.0238 0.0364
Loa Loa (eye worm) sugar transporter 0.0045 0.0238 0.1096
Echinococcus multilocularis solute carrier family 22 0.0045 0.0238 0.0238
Plasmodium vivax chorismate synthase 0.0216 0.1447 0.1515
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0111 0.0708 0.3086
Schistosoma mansoni glucose transport protein 0.0318 0.2171 0.2171
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0515 0.3559 0.5661
Leishmania major hypothetical protein, conserved 0.0045 0.0238 0.0997
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0071 0.0328
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Trichomonas vaginalis glucose transporter, putative 0.0099 0.0619 0.285
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0098 0.0613 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0023 0.0023
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0023 0.0104
Schistosoma mansoni hypothetical protein 0.0045 0.0238 0.0238
Brugia malayi Ubiquitin-like protein SMT3 0.0034 0.016 0.0735
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0023 0.0123
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0201 0.0201
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0062 0.0215
Plasmodium falciparum small ubiquitin-related modifier 0.0034 0.016 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0619 0.285
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0011 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0268 0.2256
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Loa Loa (eye worm) hypothetical protein 0.006 0.0345 0.1591
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0098 0.0613 0.0962
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0048 0.0242
Entamoeba histolytica protein kinase, putative 0.0098 0.0613 0.8937
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0023 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0201 0.0201
Brugia malayi hypothetical protein 0.0045 0.0238 0.1096
Brugia malayi Sugar transporter family protein 0.0045 0.0238 0.1096
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0013 0.0013 0.0013
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0045 0.0238 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.2171 1
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0048 0.0242
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Plasmodium vivax small ubiquitin-related modifier, putative 0.0034 0.016 0.0155
Brugia malayi Ets-domain containing protein 0.007 0.0417 0.1922
Trichomonas vaginalis glucose transporter, putative 0.0045 0.0238 0.1093
Onchocerca volvulus 0.0014 0.0023 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0062 0.0285
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0023 0.0329
Schistosoma mansoni hypothetical protein 0.0015 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Chlamydia trachomatis proline--tRNA ligase 0.0034 0.016 0.08
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0268 0.113
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0238 0.1093
Mycobacterium ulcerans chorismate synthase 0.0216 0.1447 1
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0048 0.0222
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0323 0.1424
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0098 0.0613 0.0634
Mycobacterium tuberculosis Conserved hypothetical protein 0.0175 0.1156 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0268 0.1234
Echinococcus granulosus dna polymerase eta 0.0021 0.0071 0.0071
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Plasmodium falciparum calcium-dependent protein kinase 4 0.0098 0.0613 0.0634
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0095 0.0596 0.2747
Brugia malayi hypothetical protein 0.0012 0.0005 0.0022
Plasmodium falciparum proline--tRNA ligase 0.0111 0.0708 0.0735
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0268 0.1775
Loa Loa (eye worm) hypothetical protein 0.0018 0.0048 0.0222
Schistosoma mansoni protein kinase 0.0098 0.0613 0.0613
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0268 0.3901
Toxoplasma gondii subtilisin SUB8 0.0013 0.0013 0.0006
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0062 0.0893
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.018 0.0945
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0033 0.0151
Trypanosoma brucei unspecified product 0.0021 0.0071 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0018 0.0048 0.0692
Echinococcus multilocularis solute carrier family 22 0.0045 0.0238 0.0238
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0252 0.116
Schistosoma mansoni hypothetical protein 0.0045 0.0238 0.0238
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trypanosoma brucei unspecified product 0.0015 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.0136
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0062 0.0215
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.018 0.1493
Trypanosoma brucei small ubiquitin-related modifier 0.0034 0.016 0.0664
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0062 0.027
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Toxoplasma gondii subtilisin SUB6 0.0013 0.0013 0.0006
Echinococcus granulosus Small ubiquitin modifier 2 0.0034 0.016 0.016
Toxoplasma gondii transporter, major facilitator family protein 0.0045 0.0238 0.0364
Brugia malayi Fli-1 protein 0.0213 0.1427 0.6571
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0249 0.0249
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0013 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trypanosoma cruzi hexose transporter, putative 0.0099 0.0619 0.2732
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0013 0.0013 0.0038
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0048 0.0061
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0048 0.0222
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0048 0.0154
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0045
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Leishmania major glucose transporter/membrane transporter D2, putative 0.0099 0.0619 0.2691
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Leishmania major small ubiquitin protein, putative 0.0034 0.016 0.0649
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Toxoplasma gondii hypothetical protein 0.0053 0.03 0.0462
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0095 0.0596 0.0596
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0249 0.1149
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0095 0.0596 0.8831
Trypanosoma cruzi hexose transporter 0.0099 0.0619 0.2732
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0023 0.006
Treponema pallidum prolyl-tRNA synthetase 0.0034 0.016 1
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0201 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0033 0.0151
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.2747
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0098 0.0613 0.0634
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0013 0.0013 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0013 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0099 0.0619 0.285
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.018 0.1164
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0048 0.034
Onchocerca volvulus 0.0045 0.0238 0.1799
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0114 0.0114
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0098 0.0613 0.2822
Plasmodium falciparum calcium-dependent protein kinase 1 0.0098 0.0613 0.0634
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0114 0.0464
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.2747
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0071 0.1031
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0048 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Mycobacterium ulcerans integral membrane transport protein 0.0045 0.0238 0.1566
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0001 0.0003
Toxoplasma gondii subtilisin SUB5 0.0013 0.0013 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0099 0.0619 0.285
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Echinococcus multilocularis dna polymerase eta 0.0021 0.0071 0.0071
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0014 0.0023 0.0068
Echinococcus granulosus GPCR family 2 0.0015 0.003 0.003
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0013 0.0013 0.0013
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0062 0.0231
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0013 0.0013 0.0038
Trypanosoma brucei unspecified product 0.0015 0.0025 0.0067
Trypanosoma cruzi subtilisin peptidase 0.0013 0.0013 0.0056
Brugia malayi hypothetical protein 0.0039 0.0201 0.0925
Schistosoma mansoni DNA polymerase eta 0.0021 0.0071 0.0071
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.0106 0.0674 0.5795
Onchocerca volvulus 0.0045 0.0238 0.1799
Toxoplasma gondii subtilisin SUB11 0.0013 0.0013 0.0006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0613 0.0613
Trypanosoma cruzi sugar transporter, putative 0.0045 0.0238 0.1047
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0268 0.1775
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.018 0.0176
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Schistosoma mansoni glucose transporter 0.0045 0.0238 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0033 0.0144
Onchocerca volvulus 0.0045 0.0238 0.1799
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0268 0.1775
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0062 0.0216
Trypanosoma cruzi small ubiquitin protein, putative 0.0034 0.016 0.0702
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Toxoplasma gondii protein kinase, putative 0.09 0.628 1
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Trypanosoma cruzi hexose transporter, putative 0.0054 0.0303 0.1335
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0062
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0424 0.1952
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0515 0.3559 0.3749
Loa Loa (eye worm) hypothetical protein 0.0033 0.0155 0.0713
Schistosoma mansoni protein kinase 0.0098 0.0613 0.0613
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0062 0.0231
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0111 0.0708 0.3125
Schistosoma mansoni furin-1 (S08 family) 0.0013 0.0013 0.0013
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0033 0.0144
Brugia malayi hypothetical protein 0.0229 0.154 0.7095
Brugia malayi Sugar transporter family protein 0.0045 0.0238 0.1096
Leishmania major lysyl-tRNA synthetase, putative 0.0071 0.0424 0.1822
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0087 0.0382
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0071 0.0424 0.1949
Onchocerca volvulus 0.0045 0.0238 0.1799
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.0023 0.0068
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0048 0.0048
Trypanosoma brucei sugar transporter, putative 0.0045 0.0238 0.1012
Echinococcus granulosus General substrate transporter 0.0274 0.1855 0.1855
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0023 0.0123
Plasmodium falciparum calcium-dependent protein kinase 5 0.0098 0.0613 0.0634
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0048 0.0222
Loa Loa (eye worm) hypothetical protein 0.0045 0.0238 0.1096
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0013 0.0013 0.0056
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.0106 0.0674 1
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0039 0.0199 0.0915
Echinococcus granulosus lysyl tRNA synthetase 0.0071 0.0424 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Plasmodium vivax CDK-related protein kinase 6, putative 0.1351 0.9472 1
Plasmodium vivax subtilisin-like protease 1 0.0186 0.1236 0.1293
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0268 0.113
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.0062 0.0215
Onchocerca volvulus 0.0045 0.0238 0.1799
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0013 0.0013 0.0062
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0048 0.0222
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0023 0.006
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0023 0.0022
Plasmodium vivax sugar transporter, putative 0.0045 0.0238 0.0237
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Echinococcus granulosus furin 0.0013 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Echinococcus granulosus expressed conserved protein 0.0102 0.0639 0.0639
Giardia lamblia Hexose transporter 0.0045 0.0238 0.346
Echinococcus multilocularis lysyl tRNA synthetase 0.0071 0.0424 0.0424
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0071 0.0273
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0046 0.0246 0.0246
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0251 0.107
Onchocerca volvulus 0.0045 0.0238 0.1799
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0071 0.0273
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0023 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0095 0.0596 0.0596
Loa Loa (eye worm) proprotein convertase 2 0.0013 0.0013 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Onchocerca volvulus 0.0045 0.0238 0.1799
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0107
Loa Loa (eye worm) endoprotease bli-4 0.0013 0.0013 0.0062
Trichomonas vaginalis glucose transporter, putative 0.0099 0.0619 0.285
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Schistosoma mansoni patched 1 0.0046 0.0249 0.0249
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0062 0.0271
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0062 0.0362 0.1664
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0318 0.2171 0.2171
Onchocerca volvulus 0.0014 0.0023 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0166 0.137
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0417 0.0417
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0282
Echinococcus multilocularis microtubule associated protein 2 0.1426 1 1
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0238 0.1093
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0249 0.0249
Entamoeba histolytica ubiquitin like protein 0.0034 0.016 0.232
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.2265 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0268 0.1775
Loa Loa (eye worm) sugar transporter 0.0318 0.2171 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.003 0.0136
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0045 0.0238 0.1012
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0023 0.0123
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0045 0.0238 0.1995
Schistosoma mansoni sugar transporter 0.0045 0.0238 0.0238
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0071 0.0404
Echinococcus granulosus solute carrier family 22 0.0045 0.0238 0.0238
Onchocerca volvulus Putative transporter 0.0045 0.0238 0.1799
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0613 0.282
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0025 0.0067
Entamoeba histolytica hypothetical protein 0.0039 0.0201 0.2921
Echinococcus multilocularis protein dispatched 1 0.0053 0.0296 0.0296
Giardia lamblia Prolyl-tRNA synthetase 0.0095 0.0596 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0268 0.1775
Chlamydia trachomatis lysine--tRNA ligase 0.0071 0.0424 0.2685
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0023 0.0068
Brugia malayi N-terminal motif family protein 0.0198 0.1322 0.609
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0273
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0095 0.0596 0.2745
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0166 0.137
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0013 0.0013 0.0013
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0045 0.0238 0.0237
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0013 0.0013 0.0038
Brugia malayi CHE-14 protein 0.0046 0.0249 0.1149
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0023 0.0149
Schistosoma mansoni survival motor neuron protein 0.0047 0.0252 0.0252
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.0312
Entamoeba histolytica hypothetical protein 0.0071 0.0424 0.6177
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.003 0.003
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0062
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0023 0.0044
Toxoplasma gondii subtilisin SUB4 0.0013 0.0013 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0013 0.0059
Trypanosoma brucei glucose transporter, putative 0.0099 0.0619 0.2703
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0263 0.1211
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0048 0.0048
Brugia malayi Ets-domain containing protein 0.007 0.0417 0.1922
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0238 0.1093
Schistosoma mansoni hypothetical protein 0.0015 0.003 0.003
Trypanosoma cruzi hexose transporter, putative 0.0099 0.0619 0.2732
Loa Loa (eye worm) hypothetical protein 0.0048 0.0263 0.1211
Toxoplasma gondii subtilisin SUB10 0.0013 0.0013 0.0006
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0023 0.0107
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0238 0.1096
Loa Loa (eye worm) hypothetical protein 0.0057 0.0323 0.1488
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0014 0.0023 0.0068
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0071 0.0424 0.1868
Echinococcus multilocularis solute carrier family 22 0.0045 0.0238 0.0238
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0023 0.0107
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0033 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0021 0.0071 0.0328
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.003 0.0136

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5.1 uM Inhibitory concentration against Streptococcus pneumoniae chorismate synthase ChEMBL. 12565943
IC50 (binding) = 5.1 uM Inhibitory concentration against Streptococcus pneumoniae chorismate synthase ChEMBL. 12565943

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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