Detailed information for compound 263403

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 477.491 | Formula: C20H23N5O7S
  • H donors: 6 H acceptors: 7 LogP: -0.64 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(CNC(=O)c1ccc(cc1)S(=O)(=O)N)NCC(=O)NC(C(=O)O)Cc1ccc(cc1)N
  • InChi: 1S/C20H23N5O7S/c21-14-5-1-12(2-6-14)9-16(20(29)30)25-18(27)11-23-17(26)10-24-19(28)13-3-7-15(8-4-13)33(22,31)32/h1-8,16H,9-11,21H2,(H,23,26)(H,24,28)(H,25,27)(H,29,30)(H2,22,31,32)
  • InChiKey: OKXPPAQBIGLBLF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0029 0.0014 0.0041
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0000022153 0.0000022153
Toxoplasma gondii AGC kinase 0.0037 0.0029 0.0496
Echinococcus granulosus CREB binding protein 0.0135 0.0214 0.0624
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0093 0.182
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Echinococcus multilocularis neuropeptide Y receptor 0.0117 0.018 0.018
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0059 0.032
Echinococcus granulosus biogenic amine 5HT receptor 0.0117 0.018 0.0525
Mycobacterium tuberculosis Conserved protein 0.0071 0.0093 0.1147
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0000022153 0.0001
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0072 0.0389
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0117 0.018 0.018
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0034 0.0667
Giardia lamblia PHD finger protein 15 0.003 0.0016 0.1195
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0072 0.0888
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0042 0.0122
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0034 0.0023 0.0067
Echinococcus granulosus hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0048 0.005 0.0146
Echinococcus multilocularis dna polymerase kappa 0.006 0.0072 0.0072
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0000022153 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0029 0.0014 0.0041
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0038 0.0032 0.0032
Echinococcus granulosus carbonic anhydrase II 0.0147 0.0237 0.0693
Echinococcus multilocularis cpg binding protein 0.0066 0.0084 0.0084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0093 0.0503
Schistosoma mansoni coup transcription factor 0.0043 0.0042 0.0122
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0017 0.0093
Echinococcus granulosus geminin 0.0542 0.0982 0.2867
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0017 0.0037
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0117 0.018 0.0525
Brugia malayi TAR-binding protein 0.0202 0.034 0.0994
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis serotonin receptor 0.0117 0.018 0.018
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0042 0.0122
Giardia lamblia DINP protein human, muc B family 0.006 0.0072 0.5454
Onchocerca volvulus 0.0057 0.0068 0.0851
Echinococcus multilocularis neuropeptide receptor A26 0.0117 0.018 0.018
Echinococcus granulosus carbonic anhydrase 0.0034 0.0023 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0042 0.0122
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0002 0.0006
Brugia malayi Serotonin receptor 0.0117 0.018 0.0525
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0261 0.0452 0.132
Brugia malayi Cation transporter family protein 0.0029 0.0014 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus thioredoxin glutathione reductase 0.0089 0.0127 0.037
Giardia lamblia Kinase, CK1 Casein kinase 0.0046 0.0047 0.3566
Onchocerca volvulus 0.0199 0.0336 0.423
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0023 0.0067
Echinococcus multilocularis dnaJ subfamily B 0.0464 0.0834 0.0834
Schistosoma mansoni biogenic amine receptor 0.0117 0.018 0.0525
Brugia malayi Cation transporter family protein 0.0029 0.0014 0.0041
Echinococcus granulosus alpha 1A adrenergic receptor 0.0117 0.018 0.0525
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0106 0.0159 0.0464
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0117 0.018 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0032 0.0628
Schistosoma mansoni polycystin 1-related 0.024 0.0412 0.1202
Echinococcus granulosus tachykinin peptides receptor 99D 0.0117 0.018 0.0525
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0042 0.0042
Schistosoma mansoni survival motor neuron protein 0.0057 0.0068 0.0197
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Onchocerca volvulus 0.0043 0.004 0.0507
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0117 0.018 0.0525
Schistosoma mansoni alpha-1 adrenergic receptor 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0117 0.018 0.0525
Echinococcus granulosus casein kinase I delta 0.0046 0.0047 0.0138
Echinococcus multilocularis glycine receptor subunit beta 0.0029 0.0014 0.0014
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni cpg binding protein 0.0066 0.0084 0.0246
Giardia lamblia Kinase, AGC AKT 0.0091 0.0132 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0029 0.0014 0.0041
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Onchocerca volvulus 0.0032 0.002 0.0253
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0046 0.0047 0.0138
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0156 0.0254 0.0254
Giardia lamblia hypothetical protein 0.0038 0.0032 0.2434
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0057 0.0309
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0037 0.0029 0.0085
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0000022153 0.0000064671
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0174 0.0509
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Echinococcus multilocularis serine threonine protein kinase 0.0037 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0178 0.0296 0.0865
Trichomonas vaginalis esterase, putative 0.0071 0.0093 0.182
Onchocerca volvulus 0.0117 0.018 0.2263
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0023 0.0067
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0057 0.0975
Echinococcus granulosus glycine receptor subunit beta 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Schistosoma mansoni myosin xvIII 0.0117 0.018 0.0525
Brugia malayi Serotonin receptor 0.0572 0.1038 0.3031
Trichomonas vaginalis CK1 family protein kinase 0.0046 0.0047 0.092
Loa Loa (eye worm) TK/DDR protein kinase 0.0113 0.0173 0.0504
Echinococcus granulosus dna polymerase eta 0.006 0.0072 0.021
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0032 0.0628
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0117 0.018 0.018
Onchocerca volvulus 0.0029 0.0014 0.0178
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0117 0.018 0.0525
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0097 0.2317
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Echinococcus multilocularis thyroid hormone receptor alpha 0.0166 0.0273 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0042 0.0122
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0117 0.018 0.0525
Echinococcus multilocularis tumor protein p63 0.0327 0.0577 0.0577
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0259 0.0757
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Onchocerca volvulus 0.0117 0.018 0.2263
Brugia malayi Hemopexin family protein 0.0283 0.0493 0.144
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0002 0.0006
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0093 0.2229
Echinococcus granulosus glycine receptor subunit alpha 1 0.0029 0.0014 0.0041
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0117 0.018 0.0525
Leishmania major protein kinase, putative 0.0024 0.0006 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0034 0.01
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0097 0.2317
Loa Loa (eye worm) hypothetical protein 0.0022 0 0.0001
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0000022153 0.0001
Echinococcus multilocularis glycine receptor subunit beta 0.0029 0.0014 0.0014
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1003 0.1851 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0017 0.0093
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0000022153 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0254 0.0741
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus multilocularis musashi 0.0032 0.002 0.002
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0093 0.0272
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0097 0.0523
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0106 0.0159 0.0464
Loa Loa (eye worm) hypothetical protein 0.0178 0.0296 0.0865
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0017 0.1308
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0072 0.1725
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0029 0.0014 0.0041
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0029 0.0014 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Echinococcus granulosus discoidin domain receptor 0.0129 0.0203 0.0593
Loa Loa (eye worm) CMGC/MAPK/NMO protein kinase 0.0156 0.0254 0.0741
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0072 0.0389
Echinococcus multilocularis serotonin receptor 0.0117 0.018 0.018
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Leishmania major cathepsin L-like protease 0.0064 0.008 0.0435
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0117 0.018 0.018
Brugia malayi G protein-coupled receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) G-protein coupled receptor 0.0117 0.018 0.0525
Echinococcus granulosus neuropeptide receptor A26 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0041 0.0223
Leishmania major protein kinase, putative 0.0024 0.0006 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0106 0.0159 0.0159
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0042 0.0122
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0029 0.0014 0.0041
Plasmodium vivax hypothetical protein, conserved 0.003 0.0016 0.0269
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.2558
Onchocerca volvulus 0.0117 0.018 0.2263
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0097 0.2317
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0293 0.0512 0.1495
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0042 0.0122
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.1838 0.3425 1
Schistosoma mansoni hypothetical protein 0.0464 0.0834 0.2436
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Schistosoma mansoni lamin 0.0032 0.002 0.0059
Echinococcus granulosus neuropeptide Y receptor 0.0117 0.018 0.0525
Echinococcus granulosus Protein kinase C brain isozyme 0.0037 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Echinococcus granulosus g-protein coupled receptor 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0333 0.0587 1
Brugia malayi P38 map kinase family protein 2 0.1003 0.1851 0.5405
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0029 0.0014 0.0041
Echinococcus multilocularis neuropeptide FF receptor 2 0.0117 0.018 0.018
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Loa Loa (eye worm) oxidoreductase 0.0021 0.0000022153 0.0000064671
Onchocerca volvulus 0.0048 0.005 0.063
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0026 0.0077
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0029 0.0014 0.0014
Brugia malayi hypothetical protein 0.0033 0.0023 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0042 0.0122
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0106 0.0159 0.0159
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0106 0.0159 0.0464
Echinococcus multilocularis G-protein coupled receptor, putative 0.0117 0.018 0.018
Brugia malayi protein kinase C II. 0.0037 0.0029 0.0085
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0026 0.0513
Loa Loa (eye worm) hypothetical protein 0.0103 0.0153 0.0447
Echinococcus multilocularis allatostatin A receptor 0.0117 0.018 0.018
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0003 0.0009
Echinococcus granulosus carbonic anhydrase 0.0034 0.0023 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0017 0.0414
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0042 0.0122
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0116 0.0337
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0081 0.1383
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0062 0.1488
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Brugia malayi Hr1 repeat family protein 0.0037 0.0029 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0093 0.0503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0037 0.0201
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0097 0.2317
Echinococcus multilocularis casein kinase I alpha 0.0046 0.0047 0.0047
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1003 0.1851 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0093 0.1147
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0042 0.0122
Echinococcus granulosus neuropeptide FF receptor 2 0.0117 0.018 0.0525
Brugia malayi hypothetical protein 0.0087 0.0124 0.0363
Plasmodium falciparum carbonic anhydrase 0.0034 0.0023 0.1834
Trichomonas vaginalis CK1 family protein kinase 0.0046 0.0047 0.092
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Echinococcus granulosus tumor protein p63 0.0327 0.0577 0.1683
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0119 0.0184 0.0184
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.008 0.0435
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0057 0.4551
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Schistosoma mansoni eyes absent homolog 0.0087 0.0124 0.0363
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0057 0.0309
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0147 0.0237 0.0693
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0006 0.0006
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0026 0.0513
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0037 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Plasmodium vivax casein kinase 1, putative 0.0046 0.0047 0.0803
Brugia malayi jmjC domain containing protein 0.0097 0.0143 0.0418
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0032 0.0174
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0117 0.018 0.0525
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0097 0.0523
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Schistosoma mansoni alpha-glucosidase 0.0137 0.0218 0.0635
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0038 0.0032 0.0174
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Brugia malayi larval opioid receptor 0.0117 0.018 0.0525
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0342 0.6672
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0091 0.0132 0.0386
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0234 0.1266
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0042 0.0122
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0037 0.0029 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0029 0.0015 0.0296
Schistosoma mansoni hypothetical protein 0.0283 0.0493 0.144
Schistosoma mansoni thyroid hormone receptor 0.0166 0.0273 0.0797
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0143 0.0418
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Onchocerca volvulus 0.0029 0.0014 0.0178
Echinococcus multilocularis dro:myosuppressin receptor 0.0117 0.018 0.018
Brugia malayi intermediate filament protein 0.0032 0.002 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Schistosoma mansoni alpha-glucosidase 0.0137 0.0218 0.0635
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0093 0.1147
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0113 0.0173 0.0504
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0083 0.0116 0.0337
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0041
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma brucei unspecified product 0.006 0.0072 0.0389
Echinococcus multilocularis ABC domain containing protein kinase 0.0048 0.005 0.005
Schistosoma mansoni intermediate filament proteins 0.0032 0.002 0.0059
Echinococcus multilocularis G protein coupled receptor 139 0.0117 0.018 0.018
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0029 0.0014 0.0041
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0333 0.0587 0.3171
Onchocerca volvulus 0.0071 0.0093 0.1173
Brugia malayi GnHR receptor homolog 0.0117 0.018 0.0525
Trypanosoma brucei carbonic anhydrase-like protein 0.0147 0.0237 0.1282
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi MH2 domain containing protein 0.0025 0.0006 0.0019
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0038 0.0032 0.2558
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0199 0.0336 0.0981
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0117 0.018 0.0525
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) thioredoxin reductase 0.0088 0.0126 0.0367
Loa Loa (eye worm) hypoxia-induced factor 1 0.0179 0.0296 0.0865
Echinococcus granulosus casein kinase i 0.0046 0.0047 0.0138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0017 0.005
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) RNA binding protein 0.0202 0.034 0.0994
Loa Loa (eye worm) AGC/PKN protein kinase 0.0037 0.0029 0.0085
Brugia malayi MH2 domain containing protein 0.0025 0.0006 0.0019
Brugia malayi glutathione reductase 0.0088 0.0126 0.0367
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Brugia malayi hypoxia-induced factor 1 0.0179 0.0296 0.0865
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.0032 0.0094
Schistosoma mansoni hypothetical protein 0.0023 0.0003 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0116 0.0337
Schistosoma mansoni ABC transporter 0.0048 0.005 0.0147
Loa Loa (eye worm) transcription factor SMAD2 0.0363 0.0644 0.1879
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0223 0.0381 0.4687
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0029 0.0014 0.0014
Onchocerca volvulus Neuropeptide F receptor homolog 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0072 0.021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0117 0.018 0.2263
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0243 0.0418 0.122
Onchocerca volvulus 0.0071 0.0093 0.1173
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0017 0.0295
Loa Loa (eye worm) ACC-1 protein 0.0029 0.0014 0.0041
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0117 0.018 0.018
Schistosoma mansoni neuropeptide F-like receptor 0.0117 0.018 0.0525
Leishmania major casein kinase, putative 0.0046 0.0047 0.0255
Schistosoma mansoni DNA polymerase eta 0.006 0.0072 0.021
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0042 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0023 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Echinococcus granulosus mitogen activated protein kinase 11 0.1003 0.1851 0.5405
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0042 0.0122
Trypanosoma brucei rac serine-threonine kinase, putative 0.0037 0.0029 0.0157
Mycobacterium tuberculosis Conserved protein 0.0071 0.0093 0.1147
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Echinococcus granulosus glycine receptor subunit alpha 1 0.0029 0.0014 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0042 0.0042
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0026 0.0513
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0308 0.054 0.2917
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0165 0.0271 0.079
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.0237 0.0693
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0283
Loa Loa (eye worm) AGC/NDR protein kinase 0.0037 0.0029 0.0085
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0117 0.018 0.018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0042 0.0122
Echinococcus multilocularis g protein coupled receptor 0.0117 0.018 0.018
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0042 0.0122
Onchocerca volvulus Alhambra homolog 0.003 0.0016 0.0199
Loa Loa (eye worm) hypothetical protein 0.0243 0.0418 0.122
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0017 0.0093
Echinococcus granulosus dro:myosuppressin receptor 0.0117 0.018 0.0525
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0042 0.0042
Echinococcus granulosus mitogen activated protein kinase 14 0.1003 0.1851 0.5405
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.0046
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0259 0.0757
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium tuberculosis Probable oxidoreductase 0.0223 0.0381 0.4687
Loa Loa (eye worm) hypothetical protein 0.0146 0.0236 0.0689
Onchocerca volvulus 0.0046 0.0047 0.0593
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0016 0.0046
Brugia malayi hypothetical protein 0.0023 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0199 0.0336 0.0981
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Brugia malayi follicle stimulating hormone receptor 0.0354 0.0627 0.1829
Mycobacterium ulcerans hydrolase 0.0243 0.0418 1
Trypanosoma brucei casein kinase I, isoform 2 0.0046 0.0047 0.0255
Toxoplasma gondii hypothetical protein 0.0034 0.0023 0.0393
Leishmania major DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus multilocularis serine:threonine protein kinase N2 0.0037 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0029 0.0014 0.0041
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0548
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Echinococcus multilocularis CREB binding protein 0.015 0.0242 0.0242
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0093 0.0272
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0006 0.0019
Onchocerca volvulus 0.0129 0.0203 0.2556
Echinococcus granulosus peptide allatostatin:somatostatin 0.0117 0.018 0.0525
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Onchocerca volvulus 0.0071 0.0093 0.1173
Brugia malayi casein kinase 1, delta 0.0046 0.0047 0.0138
Mycobacterium tuberculosis Probable dehydrogenase 0.0201 0.0338 0.4167
Echinococcus granulosus neuropeptide Y receptor 0.0117 0.018 0.0525
Echinococcus granulosus casein kinase I alpha 0.0046 0.0047 0.0138
Leishmania major hypothetical protein, conserved 0.0052 0.0057 0.0309
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0029 0.0014 0.0041
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0006 0.0019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0000022153 0.0000064671
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0117 0.018 0.0525
Trichomonas vaginalis CK1 family protein kinase 0.0046 0.0047 0.092
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0000022153 0.0002
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Echinococcus multilocularis mitogen activated protein kinase 14 0.1003 0.1851 0.1851
Echinococcus granulosus dna polymerase kappa 0.006 0.0072 0.021
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0037 0.0201
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0042 0.0042
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0051 0.0056 0.0163
Brugia malayi hypothetical protein 0.028 0.0488 0.1426
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0042 0.0122
Schistosoma mansoni hypothetical protein 0.0542 0.0982 0.2867
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0023 0.0023
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0029 0.0014 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0072 0.0389
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0006 0.0019
Onchocerca volvulus 0.0092 0.0133 0.1675
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0017 0.0295
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) beta-lactamase 0.0071 0.0093 0.0272
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0333 0.0587 1
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0046 0.0047 0.0138
Echinococcus multilocularis g-protein coupled receptor 0.0117 0.018 0.018
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0023 0.0067
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0223 0.0381 0.4687
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0000022153 0.0001
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis lamin dm0 0.0032 0.002 0.002
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0265 0.3269
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0029 0.0015 0.0296
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1838 0.3425 0.3425
Brugia malayi hypothetical protein 0.0114 0.0174 0.0509
Echinococcus granulosus c-Jun N-terminal kinases 0.1838 0.3425 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0057 0.4551
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.054 0.2917
Loa Loa (eye worm) neuropeptide F receptor 0.0117 0.018 0.0525
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Loa Loa (eye worm) hypothetical protein 0.0062 0.0077 0.0225
Echinococcus granulosus dnaJ subfamily B 0.0464 0.0834 0.2436
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0116 0.0337
Leishmania major ABC1 protein, putative 0.0048 0.005 0.0272
Onchocerca volvulus 0.0043 0.0042 0.0525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.006 0.0072 0.021
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0293 0.0512 0.1495
Loa Loa (eye worm) PDE1B protein 0.0975 0.1798 0.5248
Echinococcus granulosus 7tm_1 domain containing protein 0.0117 0.018 0.0525
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0038 0.0032 0.2434
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0093 0.0093
Loa Loa (eye worm) LGC-31 protein 0.0029 0.0014 0.0041
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0072 0.0888
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.054 0.2917
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Onchocerca volvulus 0.0117 0.018 0.2263
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0097 0.0283
Brugia malayi Smad1 0.0025 0.0006 0.0019
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Schistosoma mansoni smad1 5 8 and 0.0025 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0097 0.0283
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0283
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus 7TM GPCR rhodopsin 0.0117 0.018 0.0525
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0042 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi excitatory GABA receptor EXP-1A 0.0029 0.0014 0.0041
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0038 0.0038
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0283
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0029 0.0015 0.0296
Onchocerca volvulus 0.0029 0.0014 0.0178
Mycobacterium tuberculosis Conserved protein 0.0071 0.0093 0.1147
Schistosoma mansoni ABC transporter 0.0048 0.005 0.0147
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.005 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Brugia malayi beta-lactamase family protein 0.0071 0.0093 0.0272
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0026 0.1506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Entamoeba histolytica casein kinase, putative 0.0046 0.0047 0.2704
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.018
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0117 0.018 0.018
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0174
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0093 0.0272
Brugia malayi CXXC zinc finger family protein 0.0063 0.0078 0.0227
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0000022153 0.0001
Echinococcus granulosus smad 0.0025 0.0006 0.0019
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0017 0.0093
Leishmania major cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Brugia malayi TAZ zinc finger family protein 0.0218 0.0372 0.1085
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0218 0.0372 0.1085
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0017 0.1375
Echinococcus multilocularis neuropeptide Y receptor 0.0117 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0023 0.0067
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0017 0.0338
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0075 0.022
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0029 0.0014 0.0041
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Brugia malayi Stress-activated protein kinase jnk-1 0.1838 0.3425 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0081 0.1943
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0088 0.0126 0.0679
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Schistosoma mansoni opsin-like receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1003 0.1851 0.5405
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0097 0.5555
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis Smad4 0.0025 0.0006 0.0006
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0117 0.018 0.018
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) ACC-1 protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0037 0.0029 0.0085
Echinococcus multilocularis casein kinase i 0.0046 0.0047 0.0047
Brugia malayi Protein kinase domain containing protein 0.0037 0.0029 0.0085
Schistosoma mansoni biogenic amine receptor 0.0117 0.018 0.0525
Brugia malayi MH1 domain containing protein 0.0025 0.0006 0.0019
Onchocerca volvulus 0.0029 0.0014 0.0178
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0047 0.0138
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0099 0.1681
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Leishmania major trypanothione reductase 0.0088 0.0126 0.0679
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0042 0.0122
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.008 0.0435
Echinococcus granulosus G protein coupled receptor 139 0.0117 0.018 0.0525
Trypanosoma cruzi ABC1 protein, putative 0.0048 0.005 0.0272
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0026 0.0077
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Plasmodium falciparum phd finger protein, putative 0.003 0.0016 0.1256
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0029 0.0014 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0199 0.0336 0.0981
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0201 0.0338 0.8095
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0034 0.01
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Echinococcus multilocularis casein kinase I alpha 0.0046 0.0047 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni neuropeptide F-like receptor 0.0117 0.018 0.0525
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0041 0.0223
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0000022153 0.0000064671
Loa Loa (eye worm) MH2 domain-containing protein 0.0363 0.0644 0.1879
Echinococcus granulosus survival motor neuron protein 1 0.028 0.0488 0.1426
Echinococcus granulosus lamin 0.0032 0.002 0.0059
Loa Loa (eye worm) hypothetical protein 0.0261 0.0452 0.132
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0147 0.0237 0.0693
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus granulosus serine:threonine protein kinase 36 0.0039 0.0034 0.01
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis mitogen activated protein kinase 11 0.1003 0.1851 0.1851
Onchocerca volvulus Glucosylceramidase homolog 0.0192 0.0322 0.4056
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0038 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0038 0.0032 0.0032
Brugia malayi neuropeptide F receptor 0.0117 0.018 0.0525
Brugia malayi MH2 domain containing protein 0.0363 0.0644 0.1879
Echinococcus granulosus nAChR subunit 0.0029 0.0014 0.0041
Schistosoma mansoni hypothetical protein 0.0123 0.0191 0.0558
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0116 0.0337
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0081 0.1943
Echinococcus multilocularis neuropeptide receptor 0.0117 0.018 0.018
Brugia malayi casein kinase I 0.0046 0.0047 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.2495 0.4665 1
Echinococcus multilocularis nAChR subunit 0.0029 0.0014 0.0014
Echinococcus granulosus protein kinase c iota type 0.0037 0.0029 0.0085
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0017 0.0093
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0088 0.0126 0.1548
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0041 0.0223
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0072 0.1408
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0117 0.018 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0017 0.0037
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Echinococcus granulosus tm gpcr rhodopsin 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable reductase 0.0201 0.0338 0.4167
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0093 0.1147
Brugia malayi Thioredoxin reductase 0.0088 0.0126 0.0367
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Schistosoma mansoni opsin-like receptor 0.0117 0.018 0.0525
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0117 0.018 0.0525
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0017 0.0093
Loa Loa (eye worm) hypothetical protein 0.0087 0.0124 0.0363
Echinococcus granulosus intermediate filament protein 0.0032 0.002 0.0059
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0117 0.018 0.0525
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0038 0.0032 0.0032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0174 0.0174
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0057 0.0068 0.0197
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0093 0.182
Schistosoma mansoni lamin 0.0032 0.002 0.0059
Schistosoma mansoni hypothetical protein 0.0542 0.0982 0.2867
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Brugia malayi bHLH-PAS transcription factor 0.0043 0.004 0.0118
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0055
Echinococcus granulosus CREB binding protein 0.0036 0.0027 0.008
Brugia malayi Protein kinase domain containing protein 0.0078 0.0108 0.0314
Brugia malayi Cation transporter family protein 0.0029 0.0014 0.0041
Echinococcus multilocularis casein kinase I delta 0.0046 0.0047 0.0047
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni opsin-like receptor 0.0117 0.018 0.0525
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0093 0.1147
Brugia malayi G-protein coupled receptor 0.0117 0.018 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0026 0.0142
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0017 0.0295
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0093 0.2229
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0093 0.1147
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.0032 0.0094
Brugia malayi Matrixin family protein 0.0482 0.0869 0.2538
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0029 0.0015 0.0296
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0091 0.0132 0.0714
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.0237 0.1282
Plasmodium falciparum ABC1 family, putative 0.0048 0.005 0.4013
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0147 0.0237 0.0693
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0038 0.0032 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Brugia malayi sulfakinin receptor protein 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0052 0.0057 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0023 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Echinococcus multilocularis somatostatin receptor 0.0117 0.018 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0117 0.018 0.018
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0081 0.0237
Plasmodium falciparum glutathione reductase 0.003 0.0017 0.1375
Onchocerca volvulus 0.0117 0.018 0.2263
Echinococcus granulosus serine:threonine protein kinase NLK 0.0156 0.0254 0.0741
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0042 0.0122
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0062 0.0766
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0042 0.0042
Echinococcus multilocularis CREB binding protein 0.0036 0.0027 0.0027
Brugia malayi hypothetical protein 0.0194 0.0325 0.0948
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0047 0.0049 0.0955
Loa Loa (eye worm) melatonin receptor type 1A 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0194 0.0325 0.0948
Loa Loa (eye worm) matrixin family protein 0.0442 0.0794 0.2318
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0072 0.0072
Onchocerca volvulus 0.0032 0.002 0.0253
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0057 0.0067 0.0195
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Leishmania major DNA polymerase eta, putative 0.006 0.0072 0.0389
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0117 0.018 0.018
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0333 0.0587 0.0587
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.0039 0.0034 0.0184
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) AGC/AKT protein kinase 0.0037 0.0029 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0093 0.182
Schistosoma mansoni alpha glucosidase 0.0035 0.0026 0.0077
Treponema pallidum NADH oxidase 0.003 0.0017 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0333 0.0587 0.1714
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0029 0.0014 0.0014
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0057 0.0975
Echinococcus multilocularis g protein coupled receptor 0.0117 0.018 0.018
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0026 0.1506
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Plasmodium falciparum thioredoxin reductase 0.0088 0.0126 1
Echinococcus granulosus orexin receptor type 2 0.0117 0.018 0.0525
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0042 0.0122
Echinococcus granulosus fmrfamide receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0093 0.0272
Schistosoma mansoni hypothetical protein 0.0034 0.0023 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0028 0.0028
Onchocerca volvulus 0.0029 0.0014 0.0178
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0116 0.0116
Onchocerca volvulus 0.0029 0.0014 0.0178
Schistosoma mansoni protein kinase 0.0046 0.0047 0.0138
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.0237 0.1282
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0106 0.0159 0.0464
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0119 0.0184 0.0536
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus protein kinase C gamma type 0.0037 0.0029 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0243 0.0418 0.5147
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0042 0.0525
Schistosoma mansoni smad1 5 8 and 0.0025 0.0006 0.0019
Trypanosoma brucei unspecified product 0.0041 0.0037 0.0201
Brugia malayi Protein kinase domain containing protein 0.0037 0.0029 0.0085
Echinococcus multilocularis lamin 0.0032 0.002 0.002
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0000022153 0.0000064671
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0117 0.018 0.0525
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus casein kinase I alpha 0.0046 0.0047 0.0138
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0034 0.01
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni Smad4 0.0025 0.0006 0.0019
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0006 0.0019
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0029 0.0014 0.0014
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0333 0.0587 0.3171
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0038 0.0032 0.2558
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0259 0.0259
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0042 0.0122
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0072 0.021
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0117 0.018 0.0525
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0017 0.1375
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0038 0.0032 0.0094
Brugia malayi hypothetical protein 0.0052 0.0057 0.0167
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Echinococcus multilocularis serine:threonine protein kinase 38 0.0037 0.0029 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0017 0.0414
Loa Loa (eye worm) NAK/GAK protein kinase 0.0078 0.0108 0.0314
Echinococcus multilocularis neuropeptide s receptor 0.0117 0.018 0.018
Onchocerca volvulus 0.0117 0.018 0.2263
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus protein kinase c epsilon type 0.0037 0.0029 0.0085
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0034 0.0667
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0029 0.0014 0.0041
Plasmodium vivax phosphodiesterase gamma, putative 0.0038 0.0032 0.0548
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0117 0.018 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0042 0.0122
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0029 0.0014 0.0041
Mycobacterium leprae Probable conserved ATP-binding protein ABC transporter 0.0048 0.005 0.1207
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0017 0.0017
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0003 0.0003
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.004 0.004
Brugia malayi G protein-coupled receptor F59B2.13 0.0117 0.018 0.0525
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.008 0.0435
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0201 0.0338 0.4167
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0117 0.018 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0042 0.0042
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0016 0.0269
Echinococcus granulosus lamin dm0 0.0032 0.002 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Schistosoma mansoni biogenic amine receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.002 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0975 0.1798 0.5248
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus cpg binding protein 0.0066 0.0084 0.0246
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0042 0.0122
Onchocerca volvulus Matrix metalloproteinase homolog 0.0442 0.0794 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0042 0.0122
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0038 0.0032 0.0032
Leishmania major hypothetical protein, conserved 0.0071 0.0093 0.0503
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0057 0.0309
Leishmania major cathepsin L-like protease 0.0064 0.008 0.0435
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0117 0.018 0.0525
Echinococcus granulosus CREB binding protein 0.0036 0.0027 0.008
Echinococcus granulosus neuropeptide receptor 0.0117 0.018 0.0525
Leishmania major mitogen-activated protein kinase kinase 2 0.0039 0.0034 0.0184
Schistosoma mansoni CREB-binding protein 2 0.0218 0.0372 0.1085
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0000022153 0.0000064671
Echinococcus multilocularis thioredoxin glutathione reductase 0.0089 0.0127 0.0127
Echinococcus granulosus GPCR family 2 0.0083 0.0116 0.0337
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0093 0.0503
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0093 0.0272
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi RNA binding protein 0.0202 0.034 0.0994
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0081 0.1943
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Echinococcus granulosus glycine receptor subunit beta 0.0029 0.0014 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Schistosoma mansoni biogenic amine (5HT) receptor 0.0117 0.018 0.0525
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.0812 1
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0042 0.0122
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0117 0.018 0.0525
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus multilocularis GPCR, family 2 0.0083 0.0116 0.0116
Toxoplasma gondii casein kinase I 0.0046 0.0047 0.0803
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0026 0.0142
Loa Loa (eye worm) hypothetical protein 0.0087 0.0124 0.0363
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0259 0.0757
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0106 0.0159 0.0464
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi PHD-finger family protein 0.003 0.0016 0.0046
Brugia malayi RNA recognition motif domain containing protein 0.0202 0.034 0.0994
Brugia malayi RE15519p 0.0117 0.018 0.0525
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0174
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0081 0.0237
Schistosoma mansoni atypical protein kinase C 0.0037 0.0029 0.0085
Schistosoma mansoni single-minded 0.0058 0.0069 0.02
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0067 0.1302
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0034 0.01
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0119 0.0184 0.0536
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0029 0.0014 0.0041
Onchocerca volvulus 0.0283 0.0493 0.621
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Echinococcus granulosus neuropeptide receptor 0.0117 0.018 0.0525
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0234 0.1266
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.008 0.0435
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0097 0.2317
Echinococcus granulosus CREB binding protein 0.0218 0.0372 0.1085
Echinococcus multilocularis neuropeptides capa receptor 0.0117 0.018 0.018
Echinococcus multilocularis dna polymerase eta 0.006 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0029 0.0015 0.0296
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0055 0.0295
Schistosoma mansoni serine/threonine kinase 0.0037 0.0029 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Giardia lamblia Kinase, ULK 0.0039 0.0034 0.2584
Brugia malayi latrophilin 2 splice variant baaae 0.0178 0.0296 0.0865
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0081 0.0081
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0026 0.0077
Schistosoma mansoni hypothetical protein 0.0057 0.0068 0.0197
Leishmania major mitochondrial DNA polymerase beta 0.0308 0.054 0.2917
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Brugia malayi Protein kinase domain containing protein 0.0057 0.0067 0.0195
Schistosoma mansoni lipoxygenase 0.0057 0.0067 0.0196
Onchocerca volvulus 0.0117 0.018 0.2263
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0097 0.2317
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0094
Echinococcus multilocularis serine:threonine protein kinase N2 0.0037 0.0029 0.0029
Plasmodium vivax ABC1 family, putative 0.0048 0.005 0.0859
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0117 0.018 0.018
Entamoeba histolytica casein kinase 1, putative 0.0046 0.0047 0.2704
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0034 0.01
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0038 0.0032 0.0094
Toxoplasma gondii thioredoxin reductase 0.0088 0.0126 0.2142
Plasmodium falciparum glutathione reductase 0.0088 0.0126 1
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0037 0.0029 0.0029
Loa Loa (eye worm) Smad1 0.0025 0.0006 0.0019
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0042 0.0122
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0093 0.1147
Schistosoma mansoni aryl hydrocarbon receptor 0.0058 0.0069 0.02
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0081 0.0438
Schistosoma mansoni carbonic anhydrase 0.0034 0.0023 0.0067
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0975 0.1798 0.5248
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0184 0.0536
Onchocerca volvulus 0.0117 0.018 0.2263
Echinococcus granulosus carbonic anhydrase 0.0034 0.0023 0.0067
Schistosoma mansoni neuropeptide f receptor 76f 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0067 0.1302
Echinococcus multilocularis fmrfamide receptor 0.0117 0.018 0.018
Trypanosoma brucei glucosidase, putative 0.0035 0.0026 0.0142
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0072 0.021
Echinococcus multilocularis casein kinase I delta 0.0046 0.0047 0.0047
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0072 0.021
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0037 0.0029 0.0029
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0975 0.1798 0.5248
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0129 0.0203 0.0593
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus multilocularis smad 0.0025 0.0006 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0122 0.019 0.3243
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni cpg binding protein 0.0066 0.0084 0.0246
Trypanosoma brucei unspecified product 0.0041 0.0037 0.0201
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0078 0.0227
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Plasmodium falciparum phosphodiesterase delta, putative 0.0038 0.0032 0.2558
Brugia malayi Dopamine receptor protein 2 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0081 0.1
Mycobacterium leprae Probable lipase LipE 0.0071 0.0093 0.2229
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0023 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0548
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Mycobacterium ulcerans hypothetical protein 0.0073 0.0097 0.2317
Echinococcus multilocularis neuropeptides capa receptor 0.0117 0.018 0.018
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0072 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Brugia malayi neuropeptide F receptor 0.0117 0.018 0.0525
Echinococcus granulosus serine:threonine protein kinase N2 0.0037 0.0029 0.0085
Loa Loa (eye worm) TAR-binding protein 0.0202 0.034 0.0994
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0108 0.0314
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0072 0.0389
Brugia malayi ORL1-like opioid receptor 0.0117 0.018 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0042 0.0122
Mycobacterium ulcerans putative regulatory protein 0.0043 0.004 0.0964
Echinococcus multilocularis protein kinase c iota type 0.0037 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0034 0.0667
Echinococcus granulosus g protein coupled receptor 0.0117 0.018 0.0525
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.2558
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0017 0.0093
Echinococcus granulosus cyclin g associated kinase 0.0078 0.0108 0.0314
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus NDR protein kinase 0.0037 0.0029 0.0085
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0017 0.005
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0117 0.018 0.0525
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0026 0.0026
Giardia lamblia Hypothetical protein 0.0038 0.0032 0.2434
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Echinococcus granulosus single minded 2 0.0043 0.004 0.0118
Onchocerca volvulus 0.0073 0.0097 0.1219
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0097 0.1193
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0143 0.0143
Echinococcus granulosus Smad4 0.0025 0.0006 0.0019
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1838 0.3425 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0017 0.0093
Echinococcus multilocularis serine:threonine protein kinase 36 0.0039 0.0034 0.0034
Schistosoma mansoni biogenic amine (5HT) receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) G-protein coupled receptor 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0000022153 0.0000064671
Schistosoma mansoni thyroid hormone receptor 0.0166 0.0273 0.0797
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0116 0.0116
Toxoplasma gondii ABC1 protein 0.0048 0.005 0.0859
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Plasmodium falciparum casein kinase 1 0.0046 0.0047 0.3748
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0067 0.1302
Loa Loa (eye worm) intermediate filament protein 0.0032 0.002 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0097 0.0283
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0037 0.0201
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0042 0.0122
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0174 0.0509
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0006 0.0019
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0097 0.5555
Loa Loa (eye worm) carbonic anhydrase 3 0.0147 0.0237 0.0693
Toxoplasma gondii ABC1 family protein 0.0074 0.0099 0.1681
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0072 0.1725
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0106 0.0308
Loa Loa (eye worm) CBP-B 0.0152 0.0246 0.0718
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0042 0.0122
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0975 0.1798 0.1798
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0174
Echinococcus multilocularis survival motor neuron protein 1 0.028 0.0488 0.0488
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0261 0.0452 0.132
Echinococcus multilocularis casein kinase I alpha 0.0046 0.0047 0.0047
Schistosoma mansoni adenoreceptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi PAS domain containing protein 0.0058 0.0069 0.02
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0199 0.0336 0.0981
Echinococcus granulosus biogenic amine 5HT receptor 0.0117 0.018 0.0525
Brugia malayi G-protein coupled receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0016 0.0269
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Echinococcus multilocularis CREB binding protein 0.0036 0.0027 0.0027
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0003 0.001
Schistosoma mansoni growth hormone secretagogue receptor 0.0117 0.018 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0029 0.0014 0.0014
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0038 0.0032 0.0032
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0029 0.0014 0.0041
Mycobacterium ulcerans ABC transporter ATP-binding protein 0.0048 0.005 0.1207
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0123 0.0191 0.0558
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Schistosoma mansoni cpg binding protein 0.0063 0.0078 0.0227
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0202 0.034 0.0994
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Echinococcus multilocularis carbonic anhydrase II 0.0147 0.0237 0.0237
Mycobacterium leprae PROBABLE HYDROLASE 0.0243 0.0418 1
Brugia malayi MH1 domain containing protein 0.0025 0.0006 0.0019
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0037 0.0029 0.0085
Trypanosoma brucei ABC1 protein, putative 0.0048 0.005 0.0272
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0062 0.1059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Echinococcus granulosus neuropeptides capa receptor 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0097 0.2317
Echinococcus multilocularis cyclin g associated kinase 0.0078 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0097 0.2317
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0062 0.4946
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0017 0.0295
Brugia malayi nuclear receptor NHR-88 0.0043 0.0042 0.0122
Trypanosoma cruzi ABC1 protein, putative 0.0048 0.005 0.0272
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0097 0.5555
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0081 0.0237
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0072 0.0389
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0259 0.0259
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0116 0.0337
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Echinococcus granulosus neuropeptide s receptor 0.0117 0.018 0.0525
Onchocerca volvulus 0.0063 0.0078 0.0978
Echinococcus granulosus sex peptide receptor 0.0117 0.018 0.0525
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus granulosus casein kinase I alpha 0.0046 0.0047 0.0138
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Onchocerca volvulus 0.0117 0.018 0.2263
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0117 0.018 0.0525
Echinococcus multilocularis geminin 0.0542 0.0982 0.0982
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0046 0.0047 0.0138
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0046 0.0047 0.0255
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0106 0.0159 0.0464
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0016 0.0046
Leishmania major carbonic anhydrase-like protein 0.0147 0.0237 0.1282
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0003 0.0009
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0029 0.0014 0.0014
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.002 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Plasmodium vivax glutathione reductase, putative 0.0088 0.0126 0.2142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0042 0.0122
Brugia malayi putative neuropeptide receptor NPR1 0.0117 0.018 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0029 0.0014 0.0041
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Brugia malayi p70 ribosomal S6 kinase beta 0.0037 0.0029 0.0085
Echinococcus multilocularis peregrin 0.0034 0.0023 0.0023
Brugia malayi Melatonin receptor type 1A 0.0117 0.018 0.0525
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0042 0.0525
Trypanosoma brucei trypanothione reductase 0.0088 0.0126 0.0679
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0017 0.0338
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0017 0.0414
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Schistosoma mansoni hypothetical protein 0.003 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Echinococcus multilocularis neuropeptide receptor 0.0117 0.018 0.018
Echinococcus granulosus casein kinase I delta 0.0046 0.0047 0.0138
Onchocerca volvulus 0.0117 0.018 0.2263
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0072 0.4136
Leishmania major hypothetical protein, conserved 0.0038 0.0032 0.0174
Schistosoma mansoni hypothetical protein 0.0114 0.0174 0.0509
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0201 0.0338 0.4167
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0003 0.0009
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0725 0.1327 0.1327
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0234 0.1266
Loa Loa (eye worm) neuropeptide F receptor 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus tm gpcr rhodopsin 0.0117 0.018 0.0525
Onchocerca volvulus 0.0037 0.0029 0.0369
Echinococcus multilocularis CREB binding protein 0.0036 0.0027 0.0027
Echinococcus granulosus somatostatin receptor 0.0117 0.018 0.0525
Mycobacterium ulcerans beta-lactamase 0.0071 0.0093 0.2229
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0003 0.0009
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0039 0.0034 0.0184
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0007 0.0022
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0029 0.0014 0.0041
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0041 0.0223
Plasmodium falciparum thioredoxin reductase 0.003 0.0017 0.1375
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0085
Leishmania major cathepsin L-like protease 0.0064 0.008 0.0435
Onchocerca volvulus Putative nachr subunit 0.0029 0.0014 0.0178
Brugia malayi AKH receptor 0.0117 0.018 0.0525
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0042 0.0122
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0038 0.0032 0.0094
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0093 0.1147
Brugia malayi putative neuropeptide receptor 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0072 0.0389
Brugia malayi beta-lactamase 0.0071 0.0093 0.0272
Plasmodium falciparum phosphodiesterase gamma, putative 0.0038 0.0032 0.2558
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0097 0.1193
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.0525
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Leishmania major hypothetical protein, conserved 0.0038 0.0032 0.0174
Mycobacterium ulcerans lipase LipD 0.0071 0.0093 0.2229
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0042 0.0122
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0026 0.0513
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Schistosoma mansoni smad1 5 8 and 0.0025 0.0006 0.0019
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0117 0.018 0.0525
Loa Loa (eye worm) matrixin family protein 0.0482 0.0869 0.2538
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0354 0.0627 0.1829
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) glutathione reductase 0.0088 0.0126 0.0367
Brugia malayi Dopamine receptor 0.0117 0.018 0.0525
Plasmodium vivax thioredoxin reductase, putative 0.0088 0.0126 0.2142
Onchocerca volvulus Matrilysin homolog 0.0199 0.0336 0.423
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Brugia malayi ecdysteroid receptor 0.0043 0.0042 0.0122
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0201 0.0338 0.4167
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0029 0.0014 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0042 0.0122
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0042 0.0122
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0097 0.0523
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0016 0.0016
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0062 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0117 0.018 0.018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0333 0.0587 1
Loa Loa (eye worm) TYRA-2 protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.028 0.0488 0.1426
Schistosoma mansoni smad 0.0025 0.0006 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0117 0.018 0.018
Schistosoma mansoni histamine h1 receptor 0.0117 0.018 0.0525
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Brugia malayi Protein kinase domain containing protein 0.0129 0.0203 0.0593
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0003 0.0009
Echinococcus multilocularis sex peptide receptor 0.0117 0.018 0.018
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.007 0.0378
Echinococcus granulosus serotonin receptor 0.0117 0.018 0.0525
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0072 0.1408
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0072 0.021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0042 0.0122
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0333 0.0587 0.3171
Echinococcus multilocularis mitogen activated protein kinase 14 0.1003 0.1851 0.1851
Mycobacterium tuberculosis Probable conserved ATP-binding protein ABC transporter 0.0048 0.005 0.0621
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0017 0.0093
Echinococcus multilocularis mitogen activated protein kinase 11 0.1003 0.1851 0.1851
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0201 0.0338 0.4167
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus g protein coupled receptor 0.0117 0.018 0.0525
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0023 0.0067
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0093 0.2229
Echinococcus granulosus peregrin 0.0034 0.0023 0.0067
Echinococcus granulosus tar DNA binding protein 0.0202 0.034 0.0994
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Brugia malayi hypothetical protein 0.0023 0.0003 0.0009
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0017 0.0213
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.021 0.0613
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0097 0.2317
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.0237 0.0693
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0106 0.0159 0.0464
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0156 0.0254 0.0741
Echinococcus granulosus allatostatin A receptor 0.0117 0.018 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0032 0.0628
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0067 0.0067
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0017 0.005
Echinococcus granulosus glycine receptor subunit alpha 1 0.0029 0.0014 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0042 0.0122
Brugia malayi jmjC domain containing protein 0.004 0.0034 0.01
Mycobacterium ulcerans hypothetical protein 0.0071 0.0093 0.2229
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0026 0.0447
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0342 0.6672
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0223 0.0381 0.9106
Echinococcus multilocularis protein kinase c epsilon type 0.0037 0.0029 0.0029
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1003 0.1851 1
Brugia malayi Bromodomain containing protein 0.0034 0.0023 0.0067
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0038 0.011
Onchocerca volvulus Matrilysin homolog 0.0442 0.0794 1
Echinococcus multilocularis tar DNA binding protein 0.0202 0.034 0.034
Echinococcus multilocularis fmrfamide receptor 0.0117 0.018 0.018
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) matrix metalloproteinase 0.0199 0.0336 0.0981
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0067 0.0196
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0093 0.182
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0117 0.018 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Brugia malayi nuclear hormone receptor 0.0043 0.0042 0.0122
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0026 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0333 0.0587 0.3171
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0042 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi beta-lactamase family protein 0.0071 0.0093 0.0272
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0093 0.182
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0000022153 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Calcitonin receptor-like protein seb-1 0.0261 0.0452 0.132
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0123 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Mycobacterium ulcerans hypothetical protein 0.0162 0.0265 0.6351
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus ABC domain containing protein kinase 0.0048 0.005 0.0147
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0029 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0042 0.0122
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0117 0.018 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus granulosus neuropeptides capa receptor 0.0117 0.018 0.0525
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Brugia malayi steroid hormone receptor 0.0043 0.0042 0.0122
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0038 0.0032 0.0174
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0725 0.1327 0.3875
Brugia malayi chaperone-activity of bc1 complex-like, mitochondrial, putative 0.0048 0.005 0.0147
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Brugia malayi nuclear receptor RXR 0.0023 0.0003 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0038 0.0032 0.0094
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0042 0.0122
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.0039 0.0034 0.0184
Brugia malayi Tachykinin-like peptides receptor 99D 0.0117 0.018 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus granulosus g protein coupled receptor 0.0117 0.018 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1003 0.1851 1
Brugia malayi Dopamine receptor protein 1 0.0117 0.018 0.0525
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0042 0.0122
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0037 0.0029 0.0159
Toxoplasma gondii hypothetical protein 0.005 0.0053 0.0909

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 210 nM Dissociation constant against human carbonic anhydrase II at 37 degree centigrade ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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