Detailed information for compound 264089

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 534.542 | Formula: C22H26N6O8S
  • H donors: 7 H acceptors: 8 LogP: -1.3 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 3
  • SMILES: O=C(NCC(=O)NC(C(=O)O)Cc1ccc(cc1)N)CNC(=O)CNC(=O)c1ccc(cc1)S(=O)(=O)N
  • InChi: 1S/C22H26N6O8S/c23-15-5-1-13(2-6-15)9-17(22(33)34)28-20(31)12-26-18(29)10-25-19(30)11-27-21(32)14-3-7-16(8-4-14)37(24,35)36/h1-8,17H,9-12,23H2,(H,25,30)(H,26,29)(H,27,32)(H,28,31)(H,33,34)(H2,24,35,36)
  • InChiKey: VTJOZQNEBCZEMS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0028 0.0028
Onchocerca volvulus 0.0029 0.0014 0.0178
Schistosoma mansoni hypothetical protein 0.0034 0.0023 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0093 0.0272
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0116 0.0116
Onchocerca volvulus 0.0029 0.0014 0.0178
Schistosoma mansoni protein kinase 0.0046 0.0047 0.0138
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0119 0.0184 0.0536
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0106 0.0159 0.0464
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.0237 0.1282
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Loa Loa (eye worm) matrixin family protein 0.0442 0.0794 0.2318
Loa Loa (eye worm) hypothetical protein 0.0194 0.0325 0.0948
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0333 0.0587 0.0587
Echinococcus multilocularis g protein coupled receptor 0.0117 0.018 0.018
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Leishmania major DNA polymerase eta, putative 0.006 0.0072 0.0389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0057 0.0067 0.0195
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Onchocerca volvulus 0.0032 0.002 0.0253
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0072 0.0072
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0029 0.0014 0.0014
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0333 0.0587 0.1714
Treponema pallidum NADH oxidase 0.003 0.0017 1
Schistosoma mansoni alpha glucosidase 0.0035 0.0026 0.0077
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0093 0.182
Loa Loa (eye worm) AGC/AKT protein kinase 0.0037 0.0029 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.0039 0.0034 0.0184
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Echinococcus granulosus fmrfamide receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0042 0.0122
Echinococcus granulosus orexin receptor type 2 0.0117 0.018 0.0525
Plasmodium falciparum thioredoxin reductase 0.0088 0.0126 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0026 0.1506
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Echinococcus multilocularis g protein coupled receptor 0.0117 0.018 0.018
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0057 0.0975
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0023 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Loa Loa (eye worm) hypothetical protein 0.0052 0.0057 0.0167
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0117 0.018 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus multilocularis somatostatin receptor 0.0117 0.018 0.018
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0062 0.0766
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0042 0.0122
Echinococcus granulosus serine:threonine protein kinase NLK 0.0156 0.0254 0.0741
Onchocerca volvulus 0.0117 0.018 0.2263
Plasmodium falciparum glutathione reductase 0.003 0.0017 0.1375
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0081 0.0237
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0047 0.0049 0.0955
Loa Loa (eye worm) melatonin receptor type 1A 0.0117 0.018 0.0525
Brugia malayi hypothetical protein 0.0194 0.0325 0.0948
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0042 0.0042
Echinococcus multilocularis CREB binding protein 0.0036 0.0027 0.0027
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0093 0.1147
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0093 0.2229
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0017 0.0295
Brugia malayi G-protein coupled receptor 0.0117 0.018 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0026 0.0142
Plasmodium falciparum ABC1 family, putative 0.0048 0.005 0.4013
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0147 0.0237 0.0693
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.0237 0.1282
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0029 0.0015 0.0296
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0091 0.0132 0.0714
Brugia malayi Matrixin family protein 0.0482 0.0869 0.2538
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.0032 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0038 0.0032 0.0094
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Brugia malayi sulfakinin receptor protein 0.0117 0.018 0.0525
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0094
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0016 0.0269
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0117 0.018 0.0525
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0201 0.0338 0.4167
Brugia malayi G protein-coupled receptor F59B2.13 0.0117 0.018 0.0525
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.008 0.0435
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.004 0.004
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0003 0.0003
Echinococcus granulosus cpg binding protein 0.0066 0.0084 0.0246
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0975 0.1798 0.5248
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.002 0.0059
Schistosoma mansoni biogenic amine receptor 0.0117 0.018 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Echinococcus granulosus lamin dm0 0.0032 0.002 0.0059
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0057 0.0309
Leishmania major cathepsin L-like protease 0.0064 0.008 0.0435
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Leishmania major hypothetical protein, conserved 0.0071 0.0093 0.0503
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0038 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0042 0.0122
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0042 0.0122
Onchocerca volvulus Matrix metalloproteinase homolog 0.0442 0.0794 1
Echinococcus granulosus neuropeptide receptor 0.0117 0.018 0.0525
Echinococcus granulosus CREB binding protein 0.0036 0.0027 0.008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) NAK/GAK protein kinase 0.0078 0.0108 0.0314
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0017 0.0414
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0117 0.018 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0042 0.0122
Echinococcus multilocularis serine:threonine protein kinase 38 0.0037 0.0029 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Echinococcus granulosus protein kinase c epsilon type 0.0037 0.0029 0.0085
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Echinococcus multilocularis neuropeptide s receptor 0.0117 0.018 0.018
Mycobacterium leprae Probable conserved ATP-binding protein ABC transporter 0.0048 0.005 0.1207
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0029 0.0014 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0042 0.0122
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0117 0.018 0.0525
Plasmodium vivax phosphodiesterase gamma, putative 0.0038 0.0032 0.0548
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0034 0.0667
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0017 0.0017
Schistosoma mansoni Smad4 0.0025 0.0006 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0034 0.01
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0259 0.0259
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0038 0.0032 0.2558
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0333 0.0587 0.3171
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0029 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0006 0.0019
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0042 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Brugia malayi hypothetical protein 0.0052 0.0057 0.0167
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0038 0.0032 0.0094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0017 0.1375
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0117 0.018 0.0525
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0072 0.021
Echinococcus granulosus protein kinase C gamma type 0.0037 0.0029 0.0085
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0243 0.0418 0.5147
Schistosoma mansoni smad1 5 8 and 0.0025 0.0006 0.0019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0042 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus multilocularis lamin 0.0032 0.002 0.002
Brugia malayi Protein kinase domain containing protein 0.0037 0.0029 0.0085
Trypanosoma brucei unspecified product 0.0041 0.0037 0.0201
Echinococcus granulosus casein kinase I alpha 0.0046 0.0047 0.0138
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0000022153 0.0000064671
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0117 0.018 0.0525
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0081 0.0081
Brugia malayi latrophilin 2 splice variant baaae 0.0178 0.0296 0.0865
Giardia lamblia Kinase, ULK 0.0039 0.0034 0.2584
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0055 0.0295
Schistosoma mansoni serine/threonine kinase 0.0037 0.0029 0.0085
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0029 0.0015 0.0296
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Leishmania major mitochondrial DNA polymerase beta 0.0308 0.054 0.2917
Schistosoma mansoni hypothetical protein 0.0057 0.0068 0.0197
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0026 0.0077
Schistosoma mansoni lipoxygenase 0.0057 0.0067 0.0196
Brugia malayi Protein kinase domain containing protein 0.0057 0.0067 0.0195
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0097 0.2317
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0029 0.0014 0.0041
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0119 0.0184 0.0536
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0034 0.01
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0067 0.1302
Schistosoma mansoni atypical protein kinase C 0.0037 0.0029 0.0085
Schistosoma mansoni single-minded 0.0058 0.0069 0.02
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0081 0.0237
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Onchocerca volvulus 0.0283 0.0493 0.621
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0097 0.2317
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.008 0.0435
Echinococcus granulosus neuropeptide receptor 0.0117 0.018 0.0525
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0234 0.1266
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis dna polymerase eta 0.006 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis neuropeptides capa receptor 0.0117 0.018 0.018
Echinococcus granulosus CREB binding protein 0.0218 0.0372 0.1085
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0117 0.018 0.0525
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0042 0.0122
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0259 0.0757
Loa Loa (eye worm) hypothetical protein 0.0087 0.0124 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0026 0.0142
Toxoplasma gondii casein kinase I 0.0046 0.0047 0.0803
Echinococcus multilocularis GPCR, family 2 0.0083 0.0116 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi PHD-finger family protein 0.003 0.0016 0.0046
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0106 0.0159 0.0464
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0174
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Brugia malayi RE15519p 0.0117 0.018 0.0525
Brugia malayi RNA recognition motif domain containing protein 0.0202 0.034 0.0994
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0000022153 0.0000064671
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Schistosoma mansoni CREB-binding protein 2 0.0218 0.0372 0.1085
Leishmania major mitogen-activated protein kinase kinase 2 0.0039 0.0034 0.0184
Brugia malayi RNA binding protein 0.0202 0.034 0.0994
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0093 0.0272
Echinococcus granulosus GPCR family 2 0.0083 0.0116 0.0337
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0093 0.0503
Echinococcus multilocularis thioredoxin glutathione reductase 0.0089 0.0127 0.0127
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0081 0.1943
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.0812 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0117 0.018 0.0525
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Echinococcus granulosus glycine receptor subunit beta 0.0029 0.0014 0.0041
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.2558
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0034 0.0667
Echinococcus granulosus g protein coupled receptor 0.0117 0.018 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0042 0.0122
Mycobacterium ulcerans putative regulatory protein 0.0043 0.004 0.0964
Echinococcus multilocularis protein kinase c iota type 0.0037 0.0029 0.0029
Brugia malayi ORL1-like opioid receptor 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0072 0.0389
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0017 0.005
Echinococcus granulosus NDR protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus cyclin g associated kinase 0.0078 0.0108 0.0314
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0017 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Giardia lamblia Hypothetical protein 0.0038 0.0032 0.2434
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0026 0.0026
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0117 0.018 0.0525
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Onchocerca volvulus 0.0073 0.0097 0.1219
Echinococcus granulosus single minded 2 0.0043 0.004 0.0118
Mycobacterium leprae Probable lipase LipE 0.0071 0.0093 0.2229
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0081 0.1
Brugia malayi Dopamine receptor protein 2 0.0117 0.018 0.0525
Plasmodium falciparum phosphodiesterase delta, putative 0.0038 0.0032 0.2558
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0078 0.0227
Echinococcus multilocularis neuropeptides capa receptor 0.0117 0.018 0.018
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Mycobacterium ulcerans hypothetical protein 0.0073 0.0097 0.2317
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0023 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Brugia malayi neuropeptide F receptor 0.0117 0.018 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0072 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0108 0.0314
Loa Loa (eye worm) TAR-binding protein 0.0202 0.034 0.0994
Echinococcus granulosus serine:threonine protein kinase N2 0.0037 0.0029 0.0085
Trypanosoma brucei glucosidase, putative 0.0035 0.0026 0.0142
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0072 0.021
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0067 0.1302
Echinococcus multilocularis fmrfamide receptor 0.0117 0.018 0.018
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0037 0.0029 0.0029
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0072 0.021
Echinococcus multilocularis casein kinase I delta 0.0046 0.0047 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0975 0.1798 0.5248
Trypanosoma brucei unspecified product 0.0041 0.0037 0.0201
Schistosoma mansoni cpg binding protein 0.0066 0.0084 0.0246
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis smad 0.0025 0.0006 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0122 0.019 0.3243
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0129 0.0203 0.0593
Toxoplasma gondii thioredoxin reductase 0.0088 0.0126 0.2142
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0037 0.0029 0.0029
Plasmodium falciparum glutathione reductase 0.0088 0.0126 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0038 0.0032 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0034 0.01
Entamoeba histolytica casein kinase 1, putative 0.0046 0.0047 0.2704
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0117 0.018 0.018
Echinococcus multilocularis serine:threonine protein kinase N2 0.0037 0.0029 0.0029
Plasmodium vivax ABC1 family, putative 0.0048 0.005 0.0859
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0094
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0093 0.1147
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0042 0.0122
Loa Loa (eye worm) Smad1 0.0025 0.0006 0.0019
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0184 0.0536
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0975 0.1798 0.5248
Schistosoma mansoni carbonic anhydrase 0.0034 0.0023 0.0067
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0081 0.0438
Schistosoma mansoni aryl hydrocarbon receptor 0.0058 0.0069 0.02
Schistosoma mansoni neuropeptide f receptor 76f 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Echinococcus granulosus carbonic anhydrase 0.0034 0.0023 0.0067
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0029 0.0014 0.0041
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0038 0.0032 0.0032
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0029 0.0014 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Schistosoma mansoni growth hormone secretagogue receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0123 0.0191 0.0558
Mycobacterium ulcerans ABC transporter ATP-binding protein 0.0048 0.005 0.1207
Trypanosoma brucei ABC1 protein, putative 0.0048 0.005 0.0272
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0037 0.0029 0.0085
Brugia malayi MH1 domain containing protein 0.0025 0.0006 0.0019
Echinococcus multilocularis carbonic anhydrase II 0.0147 0.0237 0.0237
Mycobacterium leprae PROBABLE HYDROLASE 0.0243 0.0418 1
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0202 0.034 0.0994
Schistosoma mansoni cpg binding protein 0.0063 0.0078 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0097 0.2317
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus neuropeptides capa receptor 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0062 0.1059
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0029 0.0014 0.0041
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0174
Echinococcus multilocularis survival motor neuron protein 1 0.028 0.0488 0.0488
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0975 0.1798 0.1798
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni adenoreceptor 0.0117 0.018 0.0525
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0261 0.0452 0.132
Echinococcus multilocularis casein kinase I alpha 0.0046 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus biogenic amine 5HT receptor 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0199 0.0336 0.0981
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0117 0.018 0.0525
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Onchocerca volvulus 0.0117 0.018 0.2263
Brugia malayi PAS domain containing protein 0.0058 0.0069 0.02
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0003 0.001
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Echinococcus multilocularis CREB binding protein 0.0036 0.0027 0.0027
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0016 0.0269
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi G-protein coupled receptor 0.0117 0.018 0.0525
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0174 0.0509
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0072 0.1725
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Toxoplasma gondii ABC1 family protein 0.0074 0.0099 0.1681
Loa Loa (eye worm) carbonic anhydrase 3 0.0147 0.0237 0.0693
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0097 0.5555
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) CBP-B 0.0152 0.0246 0.0718
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0106 0.0308
Schistosoma mansoni biogenic amine (5HT) receptor 0.0117 0.018 0.0525
Echinococcus multilocularis serine:threonine protein kinase 36 0.0039 0.0034 0.0034
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0017 0.0093
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1838 0.3425 1
Echinococcus granulosus Smad4 0.0025 0.0006 0.0019
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0143 0.0143
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0097 0.1193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0000022153 0.0000064671
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0003 0.0009
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) G-protein coupled receptor 0.0117 0.018 0.0525
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0116 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0166 0.0273 0.0797
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0042 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0037 0.0201
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0097 0.0283
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0067 0.1302
Loa Loa (eye worm) intermediate filament protein 0.0032 0.002 0.0059
Plasmodium falciparum casein kinase 1 0.0046 0.0047 0.3748
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Toxoplasma gondii ABC1 protein 0.0048 0.005 0.0859
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0234 0.1266
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0725 0.1327 0.1327
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0003 0.0009
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0201 0.0338 0.4167
Schistosoma mansoni hypothetical protein 0.0114 0.0174 0.0509
Onchocerca volvulus 0.0037 0.0029 0.0369
Echinococcus granulosus tm gpcr rhodopsin 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Loa Loa (eye worm) neuropeptide F receptor 0.0117 0.018 0.0525
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0041 0.0223
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0029 0.0014 0.0041
Plasmodium falciparum thioredoxin reductase 0.003 0.0017 0.1375
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0007 0.0022
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0039 0.0034 0.0184
Mycobacterium ulcerans beta-lactamase 0.0071 0.0093 0.2229
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0003 0.0009
Echinococcus granulosus somatostatin receptor 0.0117 0.018 0.0525
Echinococcus multilocularis CREB binding protein 0.0036 0.0027 0.0027
Onchocerca volvulus Putative nachr subunit 0.0029 0.0014 0.0178
Leishmania major cathepsin L-like protease 0.0064 0.008 0.0435
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0085
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trypanosoma brucei trypanothione reductase 0.0088 0.0126 0.0679
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0042 0.0525
Brugia malayi Melatonin receptor type 1A 0.0117 0.018 0.0525
Echinococcus multilocularis peregrin 0.0034 0.0023 0.0023
Brugia malayi p70 ribosomal S6 kinase beta 0.0037 0.0029 0.0085
Schistosoma mansoni hypothetical protein 0.003 0.0016 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0017 0.0414
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0017 0.0338
Echinococcus granulosus casein kinase I delta 0.0046 0.0047 0.0138
Echinococcus multilocularis neuropeptide receptor 0.0117 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Leishmania major hypothetical protein, conserved 0.0038 0.0032 0.0174
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0072 0.4136
Onchocerca volvulus 0.0117 0.018 0.2263
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Echinococcus granulosus casein kinase I alpha 0.0046 0.0047 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0046 0.0047 0.0255
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0046 0.0047 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Echinococcus multilocularis geminin 0.0542 0.0982 0.0982
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0117 0.018 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Leishmania major carbonic anhydrase-like protein 0.0147 0.0237 0.1282
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0016 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0106 0.0159 0.0464
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0029 0.0014 0.0041
Brugia malayi putative neuropeptide receptor NPR1 0.0117 0.018 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0042 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.002 0.0059
Plasmodium vivax glutathione reductase, putative 0.0088 0.0126 0.2142
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0062 0.4946
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0097 0.2317
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Echinococcus multilocularis cyclin g associated kinase 0.0078 0.0108 0.0108
Trypanosoma cruzi ABC1 protein, putative 0.0048 0.005 0.0272
Brugia malayi nuclear receptor NHR-88 0.0043 0.0042 0.0122
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0017 0.0295
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0116 0.0337
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0259 0.0259
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0081 0.0237
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0072 0.0389
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0097 0.5555
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0029 0.0014 0.0041
Echinococcus granulosus sex peptide receptor 0.0117 0.018 0.0525
Onchocerca volvulus 0.0063 0.0078 0.0978
Echinococcus granulosus neuropeptide s receptor 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Mycobacterium tuberculosis Probable conserved ATP-binding protein ABC transporter 0.0048 0.005 0.0621
Echinococcus multilocularis mitogen activated protein kinase 14 0.1003 0.1851 0.1851
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0333 0.0587 0.3171
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0201 0.0338 0.4167
Echinococcus multilocularis mitogen activated protein kinase 11 0.1003 0.1851 0.1851
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0017 0.0093
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0023 0.0067
Echinococcus granulosus g protein coupled receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus granulosus tar DNA binding protein 0.0202 0.034 0.0994
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0093 0.2229
Echinococcus granulosus peregrin 0.0034 0.0023 0.0067
Echinococcus multilocularis orexin receptor type 2 0.0117 0.018 0.018
Schistosoma mansoni smad 0.0025 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.028 0.0488 0.1426
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0333 0.0587 1
Loa Loa (eye worm) TYRA-2 protein 0.0117 0.018 0.0525
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Schistosoma mansoni histamine h1 receptor 0.0117 0.018 0.0525
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Echinococcus granulosus serotonin receptor 0.0117 0.018 0.0525
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.007 0.0378
Echinococcus multilocularis sex peptide receptor 0.0117 0.018 0.018
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0003 0.0009
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Brugia malayi Protein kinase domain containing protein 0.0129 0.0203 0.0593
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0042 0.0122
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0072 0.021
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0072 0.1408
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Plasmodium vivax thioredoxin reductase, putative 0.0088 0.0126 0.2142
Brugia malayi Dopamine receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) glutathione reductase 0.0088 0.0126 0.0367
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0354 0.0627 0.1829
Loa Loa (eye worm) matrixin family protein 0.0482 0.0869 0.2538
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0201 0.0338 0.4167
Brugia malayi ecdysteroid receptor 0.0043 0.0042 0.0122
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Onchocerca volvulus Matrilysin homolog 0.0199 0.0336 0.423
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0042 0.0122
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0097 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0042 0.0122
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0029 0.0014 0.0041
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0117 0.018 0.018
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0062 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi putative neuropeptide receptor 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0093 0.1147
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0038 0.0032 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0042 0.0122
Brugia malayi AKH receptor 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0097 0.1193
Brugia malayi beta-lactamase 0.0071 0.0093 0.0272
Plasmodium falciparum phosphodiesterase gamma, putative 0.0038 0.0032 0.2558
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0072 0.0389
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.0525
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0117 0.018 0.0525
Schistosoma mansoni smad1 5 8 and 0.0025 0.0006 0.0019
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0026 0.0513
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0042 0.0122
Mycobacterium ulcerans lipase LipD 0.0071 0.0093 0.2229
Leishmania major hypothetical protein, conserved 0.0038 0.0032 0.0174
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0038 0.0032 0.0094
Brugia malayi nuclear receptor RXR 0.0023 0.0003 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Brugia malayi chaperone-activity of bc1 complex-like, mitochondrial, putative 0.0048 0.005 0.0147
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Tachykinin-like peptides receptor 99D 0.0117 0.018 0.0525
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0042 0.0122
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.0039 0.0034 0.0184
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus granulosus g protein coupled receptor 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Toxoplasma gondii hypothetical protein 0.005 0.0053 0.0909
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0042 0.0122
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0037 0.0029 0.0159
Brugia malayi Dopamine receptor protein 1 0.0117 0.018 0.0525
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1003 0.1851 1
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi beta-lactamase family protein 0.0071 0.0093 0.0272
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0042 0.0042
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0333 0.0587 0.3171
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0123 0.0191 0.0191
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0000022153 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0261 0.0452 0.132
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0093 0.182
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0042 0.0122
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus ABC domain containing protein kinase 0.0048 0.005 0.0147
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Mycobacterium ulcerans hypothetical protein 0.0162 0.0265 0.6351
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0725 0.1327 0.3875
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0038 0.0032 0.0174
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi steroid hormone receptor 0.0043 0.0042 0.0122
Echinococcus granulosus neuropeptides capa receptor 0.0117 0.018 0.0525
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0117 0.018 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium ulcerans hypothetical protein 0.0071 0.0093 0.2229
Brugia malayi jmjC domain containing protein 0.004 0.0034 0.01
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0038 0.011
Echinococcus multilocularis protein kinase c epsilon type 0.0037 0.0029 0.0029
Brugia malayi Bromodomain containing protein 0.0034 0.0023 0.0067
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1003 0.1851 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0223 0.0381 0.9106
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0342 0.6672
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0026 0.0447
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0014 0.0041
Echinococcus multilocularis fmrfamide receptor 0.0117 0.018 0.018
Echinococcus multilocularis tar DNA binding protein 0.0202 0.034 0.034
Onchocerca volvulus Matrilysin homolog 0.0442 0.0794 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Brugia malayi nuclear hormone receptor 0.0043 0.0042 0.0122
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0026 0.0142
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0117 0.018 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0067 0.0196
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0093 0.182
Loa Loa (eye worm) matrix metalloproteinase 0.0199 0.0336 0.0981
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0029 0.0014 0.0041
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0097 0.2317
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.021 0.0613
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0017 0.0213
Brugia malayi hypothetical protein 0.0023 0.0003 0.0009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0106 0.0159 0.0464
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.0237 0.0693
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0032 0.0628
Echinococcus granulosus allatostatin A receptor 0.0117 0.018 0.0525
Brugia malayi Protein kinase domain containing protein 0.0156 0.0254 0.0741
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0042 0.0122
Echinococcus granulosus glycine receptor subunit alpha 1 0.0029 0.0014 0.0041
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0017 0.005
Schistosoma mansoni survival motor neuron protein 0.0057 0.0068 0.0197
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0042 0.0042
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Onchocerca volvulus 0.0043 0.004 0.0507
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Giardia lamblia Kinase, AGC AKT 0.0091 0.0132 1
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni cpg binding protein 0.0066 0.0084 0.0246
Echinococcus multilocularis glycine receptor subunit beta 0.0029 0.0014 0.0014
Onchocerca volvulus 0.0117 0.018 0.2263
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0117 0.018 0.0525
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0117 0.018 0.0525
Schistosoma mansoni alpha-1 adrenergic receptor 0.0117 0.018 0.0525
Echinococcus granulosus casein kinase I delta 0.0046 0.0047 0.0138
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Onchocerca volvulus 0.0032 0.002 0.0253
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0029 0.0014 0.0041
Brugia malayi Serotonin receptor 0.0117 0.018 0.0525
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0042 0.0122
Echinococcus granulosus carbonic anhydrase 0.0034 0.0023 0.0067
Echinococcus multilocularis dnaJ subfamily B 0.0464 0.0834 0.0834
Onchocerca volvulus 0.0199 0.0336 0.423
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0023 0.0067
Giardia lamblia Kinase, CK1 Casein kinase 0.0046 0.0047 0.3566
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus thioredoxin glutathione reductase 0.0089 0.0127 0.037
Brugia malayi Cation transporter family protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0261 0.0452 0.132
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0106 0.0159 0.0464
Echinococcus granulosus alpha 1A adrenergic receptor 0.0117 0.018 0.0525
Brugia malayi Cation transporter family protein 0.0029 0.0014 0.0041
Schistosoma mansoni biogenic amine receptor 0.0117 0.018 0.0525
Echinococcus granulosus tachykinin peptides receptor 99D 0.0117 0.018 0.0525
Schistosoma mansoni polycystin 1-related 0.024 0.0412 0.1202
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0032 0.0628
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0117 0.018 0.018
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0072 0.0888
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0034 0.0667
Giardia lamblia PHD finger protein 15 0.003 0.0016 0.1195
Echinococcus multilocularis dna polymerase kappa 0.006 0.0072 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) hypothetical protein 0.0048 0.005 0.0146
Echinococcus granulosus hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0034 0.0023 0.0067
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0042 0.0122
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0042 0.0122
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0017 0.0037
Echinococcus granulosus geminin 0.0542 0.0982 0.2867
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0017 0.0093
Schistosoma mansoni coup transcription factor 0.0043 0.0042 0.0122
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0093 0.0503
Echinococcus multilocularis cpg binding protein 0.0066 0.0084 0.0084
Echinococcus granulosus carbonic anhydrase II 0.0147 0.0237 0.0693
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0038 0.0032 0.0032
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0029 0.0014 0.0041
Echinococcus multilocularis neuropeptide receptor A26 0.0117 0.018 0.018
Onchocerca volvulus 0.0057 0.0068 0.0851
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0042 0.0122
Giardia lamblia DINP protein human, muc B family 0.006 0.0072 0.5454
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus multilocularis serotonin receptor 0.0117 0.018 0.018
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0117 0.018 0.0525
Brugia malayi TAR-binding protein 0.0202 0.034 0.0994
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0093 0.182
Echinococcus granulosus CREB binding protein 0.0135 0.0214 0.0624
Toxoplasma gondii AGC kinase 0.0037 0.0029 0.0496
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0000022153 0.0000022153
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0029 0.0014 0.0041
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0059 0.032
Echinococcus multilocularis neuropeptide Y receptor 0.0117 0.018 0.018
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0023 0.0067
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0072 0.0389
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0000022153 0.0001
Mycobacterium tuberculosis Conserved protein 0.0071 0.0093 0.1147
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus granulosus biogenic amine 5HT receptor 0.0117 0.018 0.0525
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0117 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0178 0.0296 0.0865
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0106 0.0159 0.0464
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0097 0.0523
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0072 0.1725
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0029 0.0014 0.0041
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0017 0.1308
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis serotonin receptor 0.0117 0.018 0.018
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0072 0.0389
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Loa Loa (eye worm) CMGC/MAPK/NMO protein kinase 0.0156 0.0254 0.0741
Echinococcus granulosus discoidin domain receptor 0.0129 0.0203 0.0593
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Leishmania major protein kinase, putative 0.0024 0.0006 0.0031
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0117 0.018 0.0525
Echinococcus granulosus glycine receptor subunit alpha 1 0.0029 0.0014 0.0041
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0038 0.0032 0.0094
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0093 0.2229
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1003 0.1851 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0042 0.0122
Echinococcus multilocularis glycine receptor subunit beta 0.0029 0.0014 0.0014
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0000022153 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0 0.0001
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0034 0.01
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0097 0.2317
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0254 0.0741
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0000022153 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0026 0.0513
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0017 0.0093
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0038 0.0032 0.0094
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0093 0.0272
Echinococcus multilocularis musashi 0.0032 0.002 0.002
Onchocerca volvulus 0.0029 0.0014 0.0178
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0117 0.018 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0032 0.0628
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) TK/DDR protein kinase 0.0113 0.0173 0.0504
Echinococcus granulosus dna polymerase eta 0.006 0.0072 0.021
Echinococcus multilocularis tumor protein p63 0.0327 0.0577 0.0577
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0042 0.0122
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0097 0.2317
Echinococcus multilocularis thyroid hormone receptor alpha 0.0166 0.0273 0.0273
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0117 0.018 0.0525
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0259 0.0757
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.0032 0.0094
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0002 0.0006
Brugia malayi Hemopexin family protein 0.0283 0.0493 0.144
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0156 0.0254 0.0254
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0046 0.0047 0.0138
Schistosoma mansoni hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0037 0.0029 0.0085
Giardia lamblia hypothetical protein 0.0038 0.0032 0.2434
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0057 0.0309
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0000022153 0.0001
Onchocerca volvulus 0.0117 0.018 0.2263
Trichomonas vaginalis esterase, putative 0.0071 0.0093 0.182
Schistosoma mansoni hypothetical protein 0.0178 0.0296 0.0865
Echinococcus multilocularis serine threonine protein kinase 0.0037 0.0029 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0000022153 0.0000064671
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0174 0.0509
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Trichomonas vaginalis CK1 family protein kinase 0.0046 0.0047 0.092
Brugia malayi Serotonin receptor 0.0572 0.1038 0.3031
Schistosoma mansoni myosin xvIII 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0057 0.0975
Echinococcus granulosus glycine receptor subunit beta 0.0029 0.0014 0.0041
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0023 0.0067
Brugia malayi hypothetical protein 0.0087 0.0124 0.0363
Echinococcus granulosus neuropeptide FF receptor 2 0.0117 0.018 0.0525
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0042 0.0122
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0038 0.0032 0.0094
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0057 0.4551
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.008 0.0435
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0119 0.0184 0.0184
Echinococcus granulosus tumor protein p63 0.0327 0.0577 0.1683
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0000022153 0.0000064671
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Plasmodium falciparum carbonic anhydrase 0.0034 0.0023 0.1834
Trichomonas vaginalis CK1 family protein kinase 0.0046 0.0047 0.092
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0147 0.0237 0.0693
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0057 0.0309
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni eyes absent homolog 0.0087 0.0124 0.0363
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0026 0.0513
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0116 0.0337
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0042 0.0122
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0017 0.0414
Echinococcus granulosus carbonic anhydrase 0.0034 0.0023 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0003 0.0009
Brugia malayi Hr1 repeat family protein 0.0037 0.0029 0.0085
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0006 0.0031
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0062 0.1488
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0081 0.1383
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0093 0.1147
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1003 0.1851 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis casein kinase I alpha 0.0046 0.0047 0.0047
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0097 0.2317
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0037 0.0201
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0093 0.0503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0117 0.018 0.018
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0029 0.0014 0.0041
Brugia malayi P38 map kinase family protein 2 0.1003 0.1851 0.5405
Onchocerca volvulus 0.0048 0.005 0.063
Loa Loa (eye worm) oxidoreductase 0.0021 0.0000022153 0.0000064671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Brugia malayi protein kinase C II. 0.0037 0.0029 0.0085
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0106 0.0159 0.0464
Echinococcus multilocularis G-protein coupled receptor, putative 0.0117 0.018 0.018
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0042 0.0122
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0106 0.0159 0.0159
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0026 0.0077
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0029 0.0014 0.0014
Brugia malayi hypothetical protein 0.0033 0.0023 0.0066
Echinococcus multilocularis allatostatin A receptor 0.0117 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0103 0.0153 0.0447
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0026 0.0513
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0041 0.0223
Echinococcus granulosus neuropeptide receptor A26 0.0117 0.018 0.0525
Loa Loa (eye worm) G-protein coupled receptor 0.0117 0.018 0.0525
Brugia malayi G protein-coupled receptor 0.0117 0.018 0.0525
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0117 0.018 0.018
Leishmania major cathepsin L-like protease 0.0064 0.008 0.0435
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0097 0.2317
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.2558
Onchocerca volvulus 0.0117 0.018 0.2263
Plasmodium vivax hypothetical protein, conserved 0.003 0.0016 0.0269
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0042 0.0122
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0106 0.0159 0.0159
Leishmania major protein kinase, putative 0.0024 0.0006 0.0031
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0029 0.0014 0.0041
Schistosoma mansoni hypothetical protein 0.0464 0.0834 0.2436
Schistosoma mansoni serine/threonine protein kinase 0.1838 0.3425 1
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0042 0.0122
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0094
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0293 0.0512 0.1495
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0333 0.0587 1
Echinococcus granulosus g-protein coupled receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Echinococcus granulosus neuropeptide Y receptor 0.0117 0.018 0.0525
Echinococcus granulosus Protein kinase C brain isozyme 0.0037 0.0029 0.0085
Schistosoma mansoni lamin 0.0032 0.002 0.0059
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Loa Loa (eye worm) AGC/PKN protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) RNA binding protein 0.0202 0.034 0.0994
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0017 0.005
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0117 0.018 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Brugia malayi glutathione reductase 0.0088 0.0126 0.0367
Brugia malayi MH2 domain containing protein 0.0025 0.0006 0.0019
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0116 0.0337
Schistosoma mansoni hypothetical protein 0.0023 0.0003 0.001
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.0032 0.0094
Brugia malayi hypoxia-induced factor 1 0.0179 0.0296 0.0865
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0041
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0072 0.021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Onchocerca volvulus Neuropeptide F receptor homolog 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0029 0.0014 0.0014
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0223 0.0381 0.4687
Loa Loa (eye worm) transcription factor SMAD2 0.0363 0.0644 0.1879
Schistosoma mansoni ABC transporter 0.0048 0.005 0.0147
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0029 0.0014 0.0041
Echinococcus multilocularis G protein coupled receptor 139 0.0117 0.018 0.018
Schistosoma mansoni intermediate filament proteins 0.0032 0.002 0.0059
Echinococcus multilocularis ABC domain containing protein kinase 0.0048 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0199 0.0336 0.0981
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0014 0.0041
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0038 0.0032 0.2558
Brugia malayi MH2 domain containing protein 0.0025 0.0006 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi GnHR receptor homolog 0.0117 0.018 0.0525
Trypanosoma brucei carbonic anhydrase-like protein 0.0147 0.0237 0.1282
Onchocerca volvulus 0.0071 0.0093 0.1173
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0333 0.0587 0.3171
Loa Loa (eye worm) hypoxia-induced factor 1 0.0179 0.0296 0.0865
Loa Loa (eye worm) thioredoxin reductase 0.0088 0.0126 0.0367
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0117 0.018 0.0525
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Echinococcus granulosus casein kinase i 0.0046 0.0047 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Brugia malayi intermediate filament protein 0.0032 0.002 0.0059
Echinococcus multilocularis dro:myosuppressin receptor 0.0117 0.018 0.018
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Onchocerca volvulus 0.0029 0.0014 0.0178
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0042 0.0122
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0093 0.1147
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0083 0.0116 0.0337
Onchocerca volvulus 0.0117 0.018 0.2263
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Schistosoma mansoni alpha-glucosidase 0.0137 0.0218 0.0635
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0083 0.0116 0.0337
Loa Loa (eye worm) hypothetical protein 0.0113 0.0173 0.0504
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma brucei unspecified product 0.006 0.0072 0.0389
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0006 0.0006
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Brugia malayi jmjC domain containing protein 0.0097 0.0143 0.0418
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0032 0.0174
Plasmodium vivax casein kinase 1, putative 0.0046 0.0047 0.0803
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0037 0.0029 0.0029
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0038 0.0032 0.0174
Schistosoma mansoni alpha-glucosidase 0.0137 0.0218 0.0635
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0097 0.0523
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0029 0.0015 0.0296
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0234 0.1266
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0091 0.0132 0.0386
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0042 0.0122
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0037 0.0029 0.0085
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0342 0.6672
Trypanosoma cruzi casein kinase, putative 0.0046 0.0047 0.0255
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Brugia malayi larval opioid receptor 0.0117 0.018 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0117 0.018 0.0525
Schistosoma mansoni hypothetical protein 0.0283 0.0493 0.144
Schistosoma mansoni thyroid hormone receptor 0.0166 0.0273 0.0797
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0143 0.0418
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0548
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0029 0.0014 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Echinococcus multilocularis serine:threonine protein kinase N2 0.0037 0.0029 0.0029
Leishmania major DNA polymerase kappa, putative 0.006 0.0072 0.0389
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Echinococcus granulosus peptide allatostatin:somatostatin 0.0117 0.018 0.0525
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0006 0.0019
Onchocerca volvulus 0.0129 0.0203 0.2556
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0093 0.0272
Echinococcus multilocularis CREB binding protein 0.015 0.0242 0.0242
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi casein kinase 1, delta 0.0046 0.0047 0.0138
Onchocerca volvulus 0.0071 0.0093 0.1173
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0006 0.0019
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0029 0.0014 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0042 0.0122
Echinococcus granulosus casein kinase I alpha 0.0046 0.0047 0.0138
Leishmania major hypothetical protein, conserved 0.0052 0.0057 0.0309
Echinococcus granulosus neuropeptide Y receptor 0.0117 0.018 0.0525
Mycobacterium tuberculosis Probable dehydrogenase 0.0201 0.0338 0.4167
Echinococcus granulosus dro:myosuppressin receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0243 0.0418 0.122
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0017 0.0093
Onchocerca volvulus Alhambra homolog 0.003 0.0016 0.0199
Echinococcus granulosus mitogen activated protein kinase 14 0.1003 0.1851 0.5405
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0042 0.0042
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0016 0.0046
Onchocerca volvulus 0.0046 0.0047 0.0593
Loa Loa (eye worm) hypothetical protein 0.0146 0.0236 0.0689
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.0046
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0259 0.0757
Mycobacterium tuberculosis Probable oxidoreductase 0.0223 0.0381 0.4687
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trypanosoma brucei casein kinase I, isoform 2 0.0046 0.0047 0.0255
Toxoplasma gondii hypothetical protein 0.0034 0.0023 0.0393
Brugia malayi follicle stimulating hormone receptor 0.0354 0.0627 0.1829
Mycobacterium ulcerans hydrolase 0.0243 0.0418 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0199 0.0336 0.0981
Brugia malayi hypothetical protein 0.0023 0.0003 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0165 0.0271 0.079
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0308 0.054 0.2917
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0026 0.0513
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0042 0.0042
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Loa Loa (eye worm) AGC/NDR protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0283
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.0237 0.0693
Echinococcus multilocularis g protein coupled receptor 0.0117 0.018 0.018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0042 0.0122
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0117 0.018 0.018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0117 0.018 0.0525
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0000022153 0.0001
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0243 0.0418 0.122
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0117 0.018 0.2263
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0054 0.0062 0.0182
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0042 0.0042
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0117 0.018 0.018
Leishmania major casein kinase, putative 0.0046 0.0047 0.0255
Schistosoma mansoni DNA polymerase eta 0.006 0.0072 0.021
Schistosoma mansoni neuropeptide F-like receptor 0.0117 0.018 0.0525
Loa Loa (eye worm) ACC-1 protein 0.0029 0.0014 0.0041
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0017 0.0295
Onchocerca volvulus 0.0071 0.0093 0.1173
Trypanosoma brucei rac serine-threonine kinase, putative 0.0037 0.0029 0.0157
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0042 0.0122
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0029 0.0014 0.0041
Echinococcus granulosus mitogen activated protein kinase 11 0.1003 0.1851 0.5405
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0023 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0094
Echinococcus granulosus glycine receptor subunit alpha 1 0.0029 0.0014 0.0041
Mycobacterium tuberculosis Conserved protein 0.0071 0.0093 0.1147
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0072 0.0888
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0093 0.0093
Loa Loa (eye worm) LGC-31 protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) PDE1B protein 0.0975 0.1798 0.5248
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0038 0.0032 0.2434
Echinococcus granulosus 7tm_1 domain containing protein 0.0117 0.018 0.0525
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0293 0.0512 0.1495
Schistosoma mansoni tar DNA-binding protein 0.0202 0.034 0.0994
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.054 0.2917
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Brugia malayi Smad1 0.0025 0.0006 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0097 0.0283
Onchocerca volvulus 0.0117 0.018 0.2263
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0029 0.0014 0.0041
Schistosoma mansoni smad1 5 8 and 0.0025 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus granulosus c-Jun N-terminal kinases 0.1838 0.3425 1
Brugia malayi hypothetical protein 0.0114 0.0174 0.0509
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1838 0.3425 0.3425
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0042 0.0122
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0037 0.0029 0.0085
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0057 0.4551
Loa Loa (eye worm) hypothetical protein 0.0062 0.0077 0.0225
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0017 0.0093
Brugia malayi Matrixin family protein 0.0199 0.0336 0.0981
Loa Loa (eye worm) neuropeptide F receptor 0.0117 0.018 0.0525
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.054 0.2917
Loa Loa (eye worm) hypothetical protein 0.006 0.0072 0.021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Onchocerca volvulus 0.0043 0.0042 0.0525
Leishmania major ABC1 protein, putative 0.0048 0.005 0.0272
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0116 0.0337
Echinococcus granulosus dnaJ subfamily B 0.0464 0.0834 0.2436
Loa Loa (eye worm) beta-lactamase 0.0071 0.0093 0.0272
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Onchocerca volvulus 0.0092 0.0133 0.1675
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0017 0.0295
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0006 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0072 0.0389
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0046 0.0047 0.0138
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0333 0.0587 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0000022153 0.0001
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Loa Loa (eye worm) hypothetical protein 0.0071 0.0093 0.0272
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0000022153 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0029 0.0014 0.0014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0223 0.0381 0.4687
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0023 0.0067
Echinococcus multilocularis g-protein coupled receptor 0.0117 0.018 0.018
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0029 0.0015 0.0296
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0265 0.3269
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0057 0.0697
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Echinococcus multilocularis lamin dm0 0.0032 0.002 0.002
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis mitogen activated protein kinase 14 0.1003 0.1851 0.1851
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0000022153 0.0002
Trichomonas vaginalis CK1 family protein kinase 0.0046 0.0047 0.092
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0021 0.0000022153 0.0000064671
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0009
Echinococcus granulosus dna polymerase kappa 0.006 0.0072 0.021
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0042 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0037 0.0201
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0023 0.0023
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0029 0.0014 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Schistosoma mansoni hypothetical protein 0.0542 0.0982 0.2867
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0042 0.0122
Brugia malayi hypothetical protein 0.028 0.0488 0.1426
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0051 0.0056 0.0163
Entamoeba histolytica hypothetical protein 0.0114 0.0174 1
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0099 0.1681
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0047 0.0138
Brugia malayi MH1 domain containing protein 0.0025 0.0006 0.0019
Onchocerca volvulus 0.0029 0.0014 0.0178
Schistosoma mansoni biogenic amine receptor 0.0117 0.018 0.0525
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0042 0.0122
Leishmania major trypanothione reductase 0.0088 0.0126 0.0679
Trypanosoma cruzi ABC1 protein, putative 0.0048 0.005 0.0272
Echinococcus granulosus G protein coupled receptor 139 0.0117 0.018 0.0525
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.008 0.0435
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0174
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0199 0.0336 0.0981
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Plasmodium falciparum phd finger protein, putative 0.003 0.0016 0.1256
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0122
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0029 0.0014 0.0041
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0026 0.0077
Trypanosoma cruzi trypanothione reductase, putative 0.0088 0.0126 0.0679
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0081 0.1943
Brugia malayi Stress-activated protein kinase jnk-1 0.1838 0.3425 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0029 0.0014 0.0041
Schistosoma mansoni neuropeptide receptor 0.0117 0.018 0.0525
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0097 0.5555
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1003 0.1851 0.5405
Schistosoma mansoni opsin-like receptor 0.0117 0.018 0.0525
Brugia malayi Protein kinase domain containing protein 0.0037 0.0029 0.0085
Echinococcus multilocularis casein kinase i 0.0046 0.0047 0.0047
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0037 0.0029 0.0085
Loa Loa (eye worm) ACC-1 protein 0.0029 0.0014 0.0041
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0117 0.018 0.018
Echinococcus multilocularis Smad4 0.0025 0.0006 0.0006
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi CXXC zinc finger family protein 0.0063 0.0078 0.0227
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0038 0.0032 0.0174
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0093 0.0272
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0117 0.018 0.018
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0218 0.0372 0.1085
Brugia malayi TAZ zinc finger family protein 0.0218 0.0372 0.1085
Leishmania major cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0017 0.0093
Echinococcus granulosus smad 0.0025 0.0006 0.0019
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0000022153 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.008 0.0435
Echinococcus multilocularis neuropeptide Y receptor 0.0117 0.018 0.018
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0017 0.1375
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0017 0.0338
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0075 0.022
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0023 0.0067
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0038 0.0038
Brugia malayi excitatory GABA receptor EXP-1A 0.0029 0.0014 0.0041
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0042 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus 7TM GPCR rhodopsin 0.0117 0.018 0.0525
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0283
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0097 0.0283
Brugia malayi beta-lactamase family protein 0.0071 0.0093 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0029 0.0085
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.005 0.0146
Schistosoma mansoni ABC transporter 0.0048 0.005 0.0147
Mycobacterium tuberculosis Conserved protein 0.0071 0.0093 0.1147
Onchocerca volvulus 0.0029 0.0014 0.0178
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0283
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0029 0.0015 0.0296
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Entamoeba histolytica casein kinase, putative 0.0046 0.0047 0.2704
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Echinococcus multilocularis rhodopsin orphan GPCR 0.0117 0.018 0.018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0026 0.1506
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0117 0.018 0.018
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0117 0.018 0.0525
Echinococcus granulosus intermediate filament protein 0.0032 0.002 0.0059
Loa Loa (eye worm) hypothetical protein 0.0087 0.0124 0.0363
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0017 0.0093
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0117 0.018 0.0525
Schistosoma mansoni opsin-like receptor 0.0117 0.018 0.0525
Schistosoma mansoni lamin 0.0032 0.002 0.0059
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0093 0.182
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0057 0.0068 0.0197
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0322 0.6291
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0174 0.0174
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0038 0.0032 0.0032
Brugia malayi Protein kinase domain containing protein 0.0078 0.0108 0.0314
Echinococcus granulosus CREB binding protein 0.0036 0.0027 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0055
Schistosoma mansoni nAChR subunit 0.0029 0.0014 0.0041
Brugia malayi bHLH-PAS transcription factor 0.0043 0.004 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0072 0.0389
Schistosoma mansoni hypothetical protein 0.0542 0.0982 0.2867
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0093 0.1147
Schistosoma mansoni opsin-like receptor 0.0117 0.018 0.0525
Echinococcus multilocularis casein kinase I delta 0.0046 0.0047 0.0047
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Brugia malayi Cation transporter family protein 0.0029 0.0014 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0081 0.1943
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0117 0.018 0.018
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0072 0.1408
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0041 0.0223
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0017 0.0093
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0088 0.0126 0.1548
Echinococcus granulosus protein kinase c iota type 0.0037 0.0029 0.0085
Echinococcus multilocularis nAChR subunit 0.0029 0.0014 0.0014
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.2495 0.4665 1
Brugia malayi casein kinase I 0.0046 0.0047 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0015 0.0296
Echinococcus multilocularis neuropeptide receptor 0.0117 0.018 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0117 0.018 0.0525
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0038 0.0032 0.0094
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0017 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0029 0.0568
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.0032 0.0628
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0117 0.018 0.0525
Entamoeba histolytica protein kinase, putative 0.0037 0.0029 0.1669
Brugia malayi Thioredoxin reductase 0.0088 0.0126 0.0367
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0093 0.1147
Mycobacterium tuberculosis Probable reductase 0.0201 0.0338 0.4167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0147 0.0237 0.0693
Loa Loa (eye worm) hypothetical protein 0.0261 0.0452 0.132
Echinococcus multilocularis mitogen activated protein kinase 11 0.1003 0.1851 0.1851
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0072 0.0389
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.0032 0.0628
Echinococcus granulosus serine:threonine protein kinase 36 0.0039 0.0034 0.01
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0038 0.0032 0.0032
Onchocerca volvulus Glucosylceramidase homolog 0.0192 0.0322 0.4056
Echinococcus granulosus nAChR subunit 0.0029 0.0014 0.0041
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0116 0.0337
Schistosoma mansoni hypothetical protein 0.0123 0.0191 0.0558
Brugia malayi MH2 domain containing protein 0.0363 0.0644 0.1879
Brugia malayi neuropeptide F receptor 0.0117 0.018 0.0525
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0038 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0032 0.0548
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0201 0.0338 0.8095
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.0032 0.0174
Loa Loa (eye worm) hypothetical protein 0.0117 0.018 0.0525
Schistosoma mansoni amine GPCR 0.0117 0.018 0.0525
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0034 0.01
Schistosoma mansoni neuropeptide F-like receptor 0.0117 0.018 0.0525
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0041 0.0223
Brugia malayi hypothetical protein 0.0117 0.018 0.0525
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0512 1
Echinococcus multilocularis casein kinase I alpha 0.0046 0.0047 0.0047
Echinococcus granulosus lamin 0.0032 0.002 0.0059
Echinococcus granulosus survival motor neuron protein 1 0.028 0.0488 0.1426
Loa Loa (eye worm) MH2 domain-containing protein 0.0363 0.0644 0.1879
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0000022153 0.0000064671

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 190 nM Dissociation constant against human carbonic anhydrase II at 37 degree centigrade ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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