Detailed information for compound 512636

Basic information

Technical information
  • TDR Targets ID: 512636
  • Name: 4-amino-N-[2-(trifluoromethyl)phenyl]benzamid e
  • MW: 280.245 | Formula: C14H11F3N2O
  • H donors: 2 H acceptors: 1 LogP: 2.96 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1ccc(cc1)C(=O)Nc1ccccc1C(F)(F)F
  • InChi: 1S/C14H11F3N2O/c15-14(16,17)11-3-1-2-4-12(11)19-13(20)9-5-7-10(18)8-6-9/h1-8H,18H2,(H,19,20)
  • InChiKey: VIDYXGSEFGOTSO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-azanyl-N-[2-(trifluoromethyl)phenyl]benzamide
  • ZINC07468092

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Schistosoma mansoni neuropeptide receptor 0.004 0.0212 0.02
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0976
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0053 0.0053
Brugia malayi G-protein alpha subunit 0.0012 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0012 0.0012 0.0036
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0074 0.0062
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.0686 0.0675
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0021 0.0076 0.1163
Brugia malayi Dopamine receptor protein 2 0.004 0.0212 0.0212
Brugia malayi nuclear receptor NHR-88 0.0018 0.0053 0.0053
Brugia malayi MH2 domain containing protein 0.0014 0.003 0.003
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0038 0.0415
Echinococcus multilocularis somatostatin receptor 0.004 0.0212 0.02
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0053 0.0041
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0121 0.0121
Trypanosoma cruzi protein farnesyltransferase, putative 0.0056 0.032 0.4584
Mycobacterium leprae conserved hypothetical protein 0.0109 0.0686 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0014 0.003 0.0018
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0056 0.0322 0.4623
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0053 0.0041
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0135 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0023 0.0205
Echinococcus granulosus apoptotic protease activating factor 1 0.056 0.3823 0.3815
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0014 0.0061
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0014 0.0023
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0265 0.0253
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0015 0.0037 0.0025
Trichomonas vaginalis Phospholipase C precursor, putative 0.0012 0.0012 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0121 0.1622
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0021 0.0074 0.0956
Schistosoma mansoni alpha-1 adrenergic receptor 0.004 0.0212 0.02
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0159 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0053 0.0053
Echinococcus multilocularis acylamino acid releasing enzyme 0.0013 0.0023 0.0011
Schistosoma mansoni bhlhzip transcription factor bigmax 0.0454 0.3091 0.3082
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0053 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Brugia malayi G-protein coupled receptor 0.004 0.0212 0.0212
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0212 0.02
Leishmania major endonuclease/exonuclease protein-like protein 0.0012 0.0012 0.0036
Onchocerca volvulus 0.0018 0.0053 0.0041
Echinococcus granulosus tar DNA binding protein 0.0177 0.1158 0.1148
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0114 0.1551
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0012 0.0036
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0012 0.0014 0.0002
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0048 0.0533
Echinococcus granulosus glutamate receptor 2 0.002 0.0072 0.006
Leishmania major oligopeptidase b 0.0013 0.0023 0.0205
Brugia malayi sulfakinin receptor protein 0.004 0.0212 0.0212
Echinococcus granulosus pyruvate kinase 0.0017 0.0048 0.0036
Mycobacterium tuberculosis Probable peptidase 0.0013 0.0023 0.0024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0093 0.0577 0.0566
Loa Loa (eye worm) calpain 5 0.0014 0.0031 0.0019
Echinococcus multilocularis dnaJ subfamily B 0.0434 0.2947 0.2939
Echinococcus multilocularis neuropeptide receptor 0.004 0.0212 0.02
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0053 0.0041
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0135 0.0123
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0078 0.0078
Entamoeba histolytica calpain large subunit domain III containing protein 0.0014 0.0031 0.0382
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0012 0.0014 0.0002
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0056 0.0322 0.4623
Onchocerca volvulus 0.0026 0.0114 0.0102
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0454 0.3091 0.3091
Loa Loa (eye worm) hypothetical protein 0.0109 0.0686 0.0675
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0277 0.1853 0.1844
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0026 0.0111 0.0099
Brugia malayi gonadotropin-releasing hormone receptor 2 0.004 0.0212 0.0212
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0002
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0023 0.0094 0.2556
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0277 0.1853 0.1844
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0014 0.0002
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0012 0.0012 0.0036
Chlamydia trachomatis pyruvate kinase 0.0033 0.0159 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0038 0.0802
Schistosoma mansoni amine GPCR 0.004 0.0212 0.02
Schistosoma mansoni hypothetical protein 0.005 0.0278 0.0267
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Echinococcus multilocularis orexin receptor type 2 0.004 0.0212 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Plasmodium vivax calpain, putative 0.0021 0.0074 0.0923
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0012 0.0014 0.0014
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0012 0.0043
Schistosoma mansoni growth hormone secretagogue receptor 0.004 0.0212 0.02
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0159 0.0147
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0074 0.0062
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0197 0.277
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0048 0.0265 0.0253
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0212 0.02
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0331 0.1788
Brugia malayi Smad1 0.0014 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Brugia malayi ImpB/MucB/SamB family protein 0.0063 0.0372 0.0372
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0014 0.003 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.0686 0.3757
Loa Loa (eye worm) calpain family protein 1 0.004 0.021 0.0199
Echinococcus multilocularis cpg binding protein 0.0032 0.0155 0.0143
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.004 0.0212 0.02
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0157 0.0145
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0331 0.032
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0014 0.0025
Echinococcus granulosus calpain 0.0021 0.0074 0.0062
Echinococcus granulosus dna polymerase eta 0.0063 0.0372 0.0361
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0078 0.0066
Schistosoma mansoni DNA polymerase eta 0.0063 0.0372 0.0361
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.004 0.0212 0.02
Echinococcus multilocularis neuropeptide s receptor 0.0515 0.3508 0.35
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0015 0.0037 0.015
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0014 0.0002
Echinococcus granulosus Smad4 0.0014 0.003 0.0018
Schistosoma mansoni hypothetical protein 0.0048 0.0265 0.0253
Trypanosoma cruzi protein farnesyltransferase, putative 0.0056 0.032 0.4584
Echinococcus granulosus TGF beta signal transducer SmadC 0.0014 0.003 0.0018
Schistosoma mansoni smad 0.0014 0.003 0.0018
Mycobacterium tuberculosis Conserved protein 0.0109 0.0686 0.1421
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0014 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0038 0.0026
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0021 0.0076 0.0943
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.004 0.0212 0.02
Schistosoma mansoni lamin 0.0026 0.0114 0.0102
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0976
Brugia malayi MH1 domain containing protein 0.0014 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0053 0.0053
Entamoeba histolytica hypothetical protein 0.0093 0.0577 1
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0074 0.0956
Schistosoma mansoni adenoreceptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0109 0.0686 0.0675
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0053 0.0041
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0012 0.0014 0.0014
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0038 0.038
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0135 0.0123
Echinococcus granulosus pyruvate kinase 0.0033 0.0159 0.0147
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0056 0.0322 0.0311
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0038 0.0415
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0121 0.0109
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0331 0.1769
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.0686 0.3743
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0197 0.039
Brugia malayi MH1 domain containing protein 0.0014 0.003 0.003
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0038 0.0026
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0012 0.0012 0.0014
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0056 0.032 0.4584
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0121 0.0121
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0074 0.0062
Echinococcus multilocularis pyruvate kinase 0.0026 0.0111 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Brugia malayi beta-lactamase 0.0109 0.0686 0.0686
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0012 0.0012 0.0036
Brugia malayi G protein-coupled receptor 0.004 0.0212 0.0212
Leishmania major geranylgeranyltransferase, putative 0.0015 0.0037 0.04
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0037 0.04
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0053 0.0041
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0053 0.0053
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0328 0.0316
Echinococcus granulosus intermediate filament protein 0.0026 0.0114 0.0102
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0012 0.0036
Echinococcus granulosus 7tm_1 domain containing protein 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0121 0.0121
Leishmania major RNA-editing complex protein MP100, putative 0.0012 0.0012 0.0036
Loa Loa (eye worm) Smad1 0.0014 0.003 0.0018
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0014 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Brugia malayi RE15519p 0.004 0.0212 0.0212
Echinococcus multilocularis musashi 0.0026 0.0114 0.0102
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0189 0.2623
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0053 0.0041
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.004 0.0212 0.02
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Onchocerca volvulus 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0025
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0038 0.0054
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0012 0.0014 0.0014
Giardia lamblia Rab geranylgeranyltransferase 0.0021 0.0076 0.1991
Schistosoma mansoni smad1 5 8 and 0.0014 0.003 0.0018
Onchocerca volvulus 0.0034 0.0167 0.0156
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0053 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0331 1
Loa Loa (eye worm) hypothetical protein 0.056 0.3823 0.3815
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0012 0.0043
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0121 0.0109
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0074 0.0956
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0265 0.0253
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0012 0.0043
Onchocerca volvulus 0.0026 0.0114 0.0102
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0976
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Brugia malayi Glutamate receptor 2 precursor 0.0025 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0049
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0212 0.02
Echinococcus granulosus somatostatin receptor 0.004 0.0212 0.02
Echinococcus granulosus caspase 2 0.056 0.3823 0.3815
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0047 0.0035
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0135 0.0123
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0023 0.0023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0331 0.5671
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0331 0.4739
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0056 0.0322 0.4623
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0331 0.1788
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0036
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0021 0.0076 0.1991
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0012 0.0012 0.0036
Loa Loa (eye worm) transcription factor SMAD2 0.0208 0.1376 0.1366
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0197 0.102
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Brugia malayi Melatonin receptor type 1A 0.004 0.0212 0.0212
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0331 0.0674
Trypanosoma cruzi prolyl endopeptidase 0.0013 0.0023 0.0205
Echinococcus granulosus g protein coupled receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0023 0.009 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.0986 0.0975
Onchocerca volvulus 0.0027 0.0121 0.0109
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.0686 0.1421
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0038 0.0415
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0012 0.0012 0.0036
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0021 0.0076 0.0064
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.0686 0.3757
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0275 0.1843 0.1834
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0074 0.0956
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0014 0.0002
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0021 0.0074 0.0956
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0976
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0074 0.0956
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0023 0.0244
Mycobacterium ulcerans hypothetical protein 0.0109 0.0686 0.3743
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0197 0.3302
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.0986 0.0986
Echinococcus multilocularis pyruvate kinase 0.0017 0.0048 0.0036
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.0686 0.1421
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0013 0.0023 0.0077
Giardia lamblia Pyruvate kinase 0.0033 0.0159 0.4592
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0159 0.2176
Onchocerca volvulus Neuropeptide F receptor homolog 0.004 0.0212 0.02
Echinococcus multilocularis sex peptide receptor 0.004 0.0212 0.02
Echinococcus multilocularis calpain 5 0.0021 0.0074 0.0062
Brugia malayi neuropeptide F receptor 0.004 0.0212 0.0212
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0121 0.0109
Plasmodium falciparum peptidase, putative 0.0013 0.0023 0.0357
Echinococcus multilocularis geminin 0.0514 0.3506 0.3498
Brugia malayi G protein-coupled receptor F59B2.13 0.004 0.0212 0.0212
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0014 0.0002
Schistosoma mansoni opsin-like receptor 0.004 0.0212 0.02
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0053 0.0053
Onchocerca volvulus 0.004 0.0212 0.02
Schistosoma mansoni transcription factor LCR-F1 0.0093 0.0577 0.0566
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0014 0.0014
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0021 0.0076 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Schistosoma mansoni amine GPCR 0.004 0.0212 0.02
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.004 0.0212 0.02
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0038 0.038
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0021 0.0076 0.0976
Onchocerca volvulus 0.0012 0.0014 0.0002
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0056 0.0322 0.4623
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.0686 0.1421
Echinococcus granulosus prolyl endopeptidase 0.0013 0.0023 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0012 0.0012 0.0014
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0056 0.032 0.1722
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0018 0.0053 0.0041
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0012 0.0012 0.0036
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.0686 0.3743
Giardia lamblia Alanyl dipeptidyl peptidase 0.0013 0.0023 0.0357
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0061 0.0061
Brugia malayi hypothetical protein 0.0027 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni neuropeptide receptor 0.004 0.0212 0.02
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0015 0.0037 0.0365
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.0102 0.0091
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0331 0.4758
Onchocerca volvulus Cell death protein 3 homolog 0.056 0.3823 0.3815
Toxoplasma gondii ABC1 family protein 0.0109 0.0686 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0212 0.02
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0012 0.0014 0.0014
Schistosoma mansoni opsin-like receptor 0.004 0.0212 0.02
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.004 0.0212 0.02
Onchocerca volvulus 0.004 0.0212 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0061 0.0049
Echinococcus multilocularis pyruvate kinase 0.0017 0.0048 0.0036
Echinococcus granulosus cpg binding protein 0.0032 0.0155 0.0143
Schistosoma mansoni neuropeptide f receptor 76f 0.004 0.0212 0.02
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Schistosoma mansoni organic anion transporter 0.0027 0.0121 0.0109
Brugia malayi polk-prov protein 0.0012 0.0014 0.0014
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0015 0.0037 0.0025
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0074 0.0956
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0197 0.0185
Onchocerca volvulus 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Echinococcus granulosus calpain 5 0.0021 0.0074 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0053 0.0053
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0197 0.039
Schistosoma mansoni hypothetical protein 0.0093 0.0577 0.0566
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0114 0.0114
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0197 0.1041
Brugia malayi GnHR receptor homolog 0.004 0.0212 0.0212
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0121 0.0109
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0038 0.0026
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0012 0.0014 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0212 0.02
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0074 0.0956
Brugia malayi SPARC precursor 0.0019 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0021 0.0076 0.0064
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0061 0.0727
Echinococcus granulosus neuropeptide receptor A26 0.0515 0.3508 0.35
Brugia malayi ORL1-like opioid receptor 0.004 0.0212 0.0212
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0056 0.032 0.032
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.004 0.0212 0.02
Trypanosoma cruzi DNA polymerase eta, putative 0.0063 0.0372 0.5358
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0053 0.0041
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0056 0.032 0.1722
Brugia malayi prostaglandin transporter 0.0027 0.0121 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0053 0.0041
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0012 0.0014
Onchocerca volvulus 0.004 0.0212 0.02
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0212 0.02
Schistosoma mansoni tar DNA-binding protein 0.0177 0.1158 0.1148
Brugia malayi isocitrate dehydrogenase 0.0015 0.0038 0.0038
Echinococcus multilocularis caspase 2 0.056 0.3823 0.3815
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0212 0.02
Brugia malayi Serotonin/octopamine receptor family protein 7 0.004 0.0212 0.0212
Schistosoma mansoni tar DNA-binding protein 0.0177 0.1158 0.1148
Schistosoma mansoni follistatin 0.0019 0.0061 0.0049
Echinococcus granulosus neuropeptide receptor 0.004 0.0212 0.02
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.004 0.0212 0.02
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0686 0.3757
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0038 0.0026
Brugia malayi hypothetical protein 0.0043 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0021 0.0076 0.1991
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0012 0.0014 0.0014
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0021 0.0076 0.0064
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0212 0.02
Echinococcus granulosus calpain A 0.0057 0.0328 0.0316
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0019 0.0007
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.031 0.0299
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0007
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0367
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0331 0.032
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0021 0.0076 0.0064
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0012 0.0012 0.0036
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0059 0.0341 0.033
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0177 0.1158 0.1148
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Brugia malayi beta-lactamase family protein 0.0109 0.0686 0.0686
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.004 0.0212 0.0212
Onchocerca volvulus 0.0027 0.0121 0.0109
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0197 0.0185
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.0686 0.0675
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0023 0.0011
Schistosoma mansoni biogenic amine receptor 0.004 0.0212 0.02
Brugia malayi intermediate filament protein 0.0026 0.0114 0.0114
Loa Loa (eye worm) prolyl oligopeptidase 0.0013 0.0023 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0074 0.0956
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.004 0.0212 0.0212
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0015 0.0037 0.04
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0012 0.0014 0.0002
Echinococcus granulosus baculoviral IAP repeat containing protein 0.1448 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0197 0.277
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus granulosus neuropeptide receptor 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0197 0.277
Onchocerca volvulus 0.0109 0.0686 0.0675
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0053 0.0041
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0048 0.0533
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0197 0.0185
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0012 0.0014
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0074 0.0956
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Giardia lamblia Rab geranylgeranyltransferase 0.0015 0.0037 0.077
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.1163
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0012 0.0036
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0012 0.0012 0.0036
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0014 0.0061
Echinococcus multilocularis pyruvate kinase 0.0033 0.0159 0.0147
Echinococcus multilocularis fmrfamide receptor 0.004 0.0212 0.02
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0023 0.0094 0.2556
Echinococcus granulosus orexin receptor type 2 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Trypanosoma cruzi lanosterol synthase, putative 0.0061 0.0358 0.5142
Giardia lamblia DINP protein human, muc B family 0.0038 0.0197 0.5791
Toxoplasma gondii hypothetical protein 0.0013 0.0023 0.0169
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.038 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Schistosoma mansoni pyruvate kinase 0.0033 0.0159 0.0147
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0053 0.0041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0326 0.2198 0.2189
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0015 0.0037 0.0025
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0331 1
Schistosoma mansoni tar DNA-binding protein 0.0177 0.1158 0.1148
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0159 0.2204
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0013 0.0023 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0053 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0078 0.0379
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0011
Schistosoma mansoni hypothetical protein 0.0104 0.0652 0.0641
Echinococcus multilocularis apoptotic protease activating factor 1 0.056 0.3823 0.3815
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0053 0.0053
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0038 0.0038
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0023 0.0023
Leishmania major lanosterol synthase, putative 0.0046 0.0252 0.3585
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0029 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0014 0.003 0.0018
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0021 0.0076 0.0064
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0012 0.0012 0.0036
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0056 0.032 0.0308
Plasmodium falciparum geranylgeranyltransferase, putative 0.0015 0.0037 0.077
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0053 0.0041
Schistosoma mansoni biogenic amine receptor 0.004 0.0212 0.02
Trypanosoma brucei unspecified product 0.0026 0.0114 0.1551
Echinococcus granulosus calpain A 0.0021 0.0074 0.0062
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0053 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0014 0.0061
Giardia lamblia Prenyltransferase 0.0056 0.032 0.9633
Loa Loa (eye worm) hypothetical protein 0.1448 1 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0197 0.0185
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Echinococcus multilocularis dna polymerase eta 0.0063 0.0372 0.0361
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0019 0.0007
Schistosoma mansoni hypothetical protein 0.004 0.0212 0.02
Entamoeba histolytica hypothetical protein 0.0093 0.0577 1
Brugia malayi steroid hormone receptor 0.0018 0.0053 0.0053
Echinococcus granulosus pyruvate kinase 0.0017 0.0048 0.0036
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0157 0.0145
Onchocerca volvulus Bile acid receptor homolog 0.0018 0.0053 0.0041
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.1448 1 1
Echinococcus granulosus expressed protein 0.0012 0.0014 0.0002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0167 0.1095 0.1084
Loa Loa (eye worm) hypothetical protein 0.0152 0.0986 0.0975
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0014 0.0025
Echinococcus multilocularis dro:myosuppressin receptor 0.004 0.0212 0.02
Echinococcus granulosus alpha 1A adrenergic receptor 0.004 0.0212 0.02
Brugia malayi beta-lactamase family protein 0.0109 0.0686 0.0686
Schistosoma mansoni bhlhzip transcription factor bigmax 0.0454 0.3091 0.3082
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Brugia malayi CCR4 0.0012 0.0012 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0053 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0265 0.0265
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0021 0.0076 0.0976
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0159 0.0147
Loa Loa (eye worm) hypothetical protein 0.0109 0.0686 0.0675
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Brugia malayi TAR-binding protein 0.0177 0.1158 0.1158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0277 0.1853 0.1844
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0212 0.02
Brugia malayi larval opioid receptor 0.004 0.0212 0.0212
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0212 0.02
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0023 0.0094 0.0445
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0212 0.02
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0332 0.4752
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0056 0.032 0.1722
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0053 0.0041
Schistosoma mansoni glutamate receptor NMDA 0.0025 0.0102 0.0091
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.0102 0.0091
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0074 0.0062
Brugia malayi Cell death protein 3 precursor 0.056 0.3823 0.3823
Echinococcus granulosus tachykinin peptides receptor 99D 0.0326 0.2198 0.2189
Mycobacterium leprae Probable lipase LipE 0.0109 0.0686 1
Schistosoma mansoni hypothetical protein 0.056 0.3823 0.3815
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0012 0.0014 0.0002
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0012 0.0014 0.0002
Brugia malayi Serotonin receptor 0.004 0.0212 0.0212
Echinococcus granulosus dro:myosuppressin receptor 0.004 0.0212 0.02
Schistosoma mansoni hypothetical protein 0.004 0.0212 0.02
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0686 1
Echinococcus granulosus pyruvate kinase 0.0033 0.0159 0.0147
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0012 0.0012 0.0043
Leishmania major farnesyltransferase beta subunit 0.0056 0.032 0.4584
Brugia malayi CXXC zinc finger family protein 0.003 0.0143 0.0143
Entamoeba histolytica protein kinase, putative 0.0014 0.0031 0.0382
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0053 0.0041
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0056 0.032 0.1722
Leishmania major DNA polymerase kappa, putative 0.0038 0.0197 0.277
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0037 0.04
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0159 0.2176
Loa Loa (eye worm) glutamate receptor 1 0.0025 0.0102 0.0091
Schistosoma mansoni histamine h1 receptor 0.004 0.0212 0.02
Echinococcus granulosus g protein coupled receptor 0.004 0.0212 0.02
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0014 0.0002
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0074 0.0062
Brugia malayi Dopamine receptor 0.004 0.0212 0.0212
Echinococcus granulosus hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0015 0.0037 0.0025
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0014 0.0002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0053 0.0041
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0038 0.038
Schistosoma mansoni cpg binding protein 0.0032 0.0155 0.0143
Onchocerca volvulus 0.004 0.0212 0.02
Echinococcus granulosus Dipeptidyl peptidase 9 0.0056 0.0322 0.0311
Onchocerca volvulus 0.004 0.0212 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Echinococcus granulosus dnaJ subfamily B 0.0434 0.2947 0.2939
Echinococcus multilocularis neuropeptide receptor A26 0.0515 0.3508 0.35
Plasmodium vivax hypothetical protein, conserved 0.0109 0.0686 1
Echinococcus multilocularis follistatin 0.0019 0.0061 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0014 0.0061
Loa Loa (eye worm) hypothetical protein 0.0109 0.0686 0.0675
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0197 0.277
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0015 0.0037 0.0025
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0053 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0053 0.0053
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0013 0.0023 0.0205
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.004 0.0212 0.02
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Echinococcus granulosus neuropeptide FF receptor 2 0.004 0.0212 0.02
Echinococcus granulosus g protein coupled receptor 0.004 0.0212 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0056 0.032 0.1722
Loa Loa (eye worm) MH1 domain-containing protein 0.0014 0.003 0.0018
Schistosoma mansoni cpg binding protein 0.0032 0.0155 0.0143
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0121 0.1652
Echinococcus multilocularis inhibitor of apoptosis protein 0.1448 1 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.004 0.0212 0.02
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0053 0.0041
Leishmania major DNA polymerase eta, putative 0.0037 0.0189 0.2649
Giardia lamblia Pyruvate kinase 0.0017 0.0048 0.1126
Entamoeba histolytica hypothetical protein 0.0093 0.0577 1
Trypanosoma brucei unspecified product 0.0026 0.0114 0.1551
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0014 0.0002
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0014 0.0002
Echinococcus granulosus smad 0.0014 0.003 0.0018
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0013 0.0023 0.0205
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0159 0.0828
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Onchocerca volvulus 0.0109 0.0686 0.0675
Echinococcus multilocularis g protein coupled receptor 0.004 0.0212 0.02
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0197 0.277
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0159 0.2041
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0023 0.0023
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0094 0.0172
Echinococcus granulosus sex peptide receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0114 0.1551
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0064
Entamoeba histolytica hypothetical protein 0.0093 0.0577 1
Toxoplasma gondii exonuclease III APE 0.0058 0.0331 0.4739
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0061 0.0727
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0093 0.0577 0.0566
Onchocerca volvulus 0.004 0.0212 0.02
Echinococcus multilocularis GPCR, family 2 0.0048 0.0265 0.0253
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0029 0.0017
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0021 0.0076 0.0076
Echinococcus multilocularis allatostatin A receptor 0.004 0.0212 0.02
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0159 0.0147
Onchocerca volvulus 0.0109 0.0686 0.0675
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0038 0.0026
Echinococcus multilocularis alpha 1A adrenergic receptor 0.004 0.0212 0.02
Brugia malayi follicle stimulating hormone receptor 0.0265 0.1777 0.1777
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0061 0.0061
Onchocerca volvulus 0.056 0.3823 0.3815
Echinococcus granulosus GPCR family 2 0.0048 0.0265 0.0253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0053 0.0041
Toxoplasma gondii hypothetical protein 0.0021 0.0076 0.0943
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trypanosoma brucei prolyl endopeptidase 0.0013 0.0023 0.0205
Echinococcus multilocularis g protein coupled receptor 0.004 0.0212 0.02
Schistosoma mansoni ATP-binding cassette transporter 0.0025 0.0102 0.0091
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0277 0.1853 0.1844
Echinococcus multilocularis expressed protein 0.0019 0.0061 0.0049
Brugia malayi putative neuropeptide receptor 0.004 0.0212 0.0212
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0197 0.0185
Loa Loa (eye worm) hypothetical protein 0.0106 0.067 0.0659
Brugia malayi calpain 5 0.0014 0.0031 0.0031
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0212 0.02
Echinococcus multilocularis fmrfamide receptor 0.004 0.0212 0.02
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0053 0.0041
Loa Loa (eye worm) hypothetical protein 0.0104 0.0652 0.0641
Trypanosoma cruzi oligopeptidase b 0.0013 0.0023 0.0205
Schistosoma mansoni lamin 0.0026 0.0114 0.0102
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0038 0.0026
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0015 0.0037 0.015
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.004 0.0212 0.02
Brugia malayi MH2 domain containing protein 0.0208 0.1376 0.1376
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0686 0.3757
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0013 0.0023 0.0244
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0056 0.032 0.1722
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0159 0.0147
Leishmania major hypothetical protein, conserved 0.0109 0.0686 1
Brugia malayi nuclear hormone receptor 0.0018 0.0053 0.0053
Entamoeba histolytica G protein alpha subunit, putative 0.0012 0.0014 0.0074
Echinococcus granulosus geminin 0.0514 0.3506 0.3498
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0109 0.0686 0.0675
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0061 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0023 0.0244
Schistosoma mansoni tar DNA-binding protein 0.0177 0.1158 0.1148
Echinococcus multilocularis G protein coupled receptor 139 0.004 0.0212 0.02
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0048 0.0267 0.0256
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Brugia malayi prolyl oligopeptidase family protein 0.0167 0.1095 0.1095
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0013 0.0023 0.0205
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus multilocularis smad 0.0014 0.003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0212 0.02
Schistosoma mansoni smad1 5 8 and 0.0014 0.003 0.0018
Schistosoma mansoni smad1 5 8 and 0.0014 0.003 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0053 0.0041
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0053 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0212 0.02
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0135 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0265 0.0253
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0057 0.0328 0.0316
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.006 0.1504
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0004
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.004 0.0212 0.0212
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0331 0.5
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0159 0.0147
Schistosoma mansoni amine GPCR 0.004 0.0212 0.02
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0074 0.0956
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0014 0.0002
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0114 0.0102
Schistosoma mansoni amine GPCR 0.004 0.0212 0.02
Schistosoma mansoni cpg binding protein 0.003 0.0143 0.0131
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Onchocerca volvulus 0.0027 0.0121 0.0109
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0038 0.0415
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0114 0.1551
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.009 0.1415
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0078 0.0379
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.004 0.0212 0.02
Giardia lamblia DNA damage repair protein 0.0012 0.0014 0.0053
Brugia malayi ecdysteroid receptor 0.0018 0.0053 0.0053
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0053 0.0041
Echinococcus granulosus neuropeptide s receptor 0.0515 0.3508 0.35
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0053 0.0041
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0159 0.0159
Brugia malayi putative neuropeptide receptor NPR1 0.004 0.0212 0.0212
Trypanosoma brucei lanosterol synthase 0.0061 0.0358 0.5142
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0029 0.0135 0.0123
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0013 0.0023 0.0024
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0102 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0076 0.0976
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0053 0.0041
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0023 0.0244
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.004 0.0212 0.02
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0057 0.0328 0.0316
Mycobacterium tuberculosis Conserved protein 0.0109 0.0686 0.1421
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0012 0.0012 0.0014
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0021 0.0076 0.0367
Loa Loa (eye worm) hypothetical protein 0.0109 0.0686 0.0675
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0038 0.0415
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0056 0.032 0.5464
Leishmania major DNA polymerase eta, putative 0.0063 0.0372 0.5358
Echinococcus granulosus glutamate receptor 2 0.0029 0.0135 0.0123
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0277 0.1853 0.1853
Mycobacterium tuberculosis Conserved protein 0.0109 0.0686 0.1421
Onchocerca volvulus 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0043 0.023 0.0218
Schistosoma mansoni hypothetical protein 0.0048 0.0265 0.0253
Brugia malayi G-protein coupled receptor 0.004 0.0212 0.0212
Mycobacterium ulcerans beta-lactamase 0.0109 0.0686 0.3743
Echinococcus multilocularis glutamate receptor 2 0.002 0.0072 0.006
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0012 0.0014 0.0014
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.0686 0.0686
Echinococcus granulosus lamin dm0 0.0026 0.0114 0.0102
Schistosoma mansoni neuropeptide receptor 0.004 0.0212 0.02
Echinococcus multilocularis neuropeptide receptor 0.004 0.0212 0.02
Onchocerca volvulus 0.004 0.0212 0.02
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0015 0.0037 0.015
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.0686 0.1421
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0023 0.0244
Echinococcus multilocularis glutamate receptor 2 0.0025 0.0102 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0053 0.0041
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0012 0.0012 0.0014
Echinococcus multilocularis serotonin receptor 0.004 0.0212 0.02
Schistosoma mansoni opsin-like receptor 0.004 0.0212 0.02
Loa Loa (eye worm) prolyl oligopeptidase 0.0167 0.1095 0.1084
Echinococcus multilocularis max protein X 0.0454 0.3091 0.3082
Giardia lamblia Rab geranylgeranyltransferase 0.0021 0.0076 0.1991
Loa Loa (eye worm) hypothetical protein 0.0055 0.031 0.0299
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0212 0.02
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0014 0.0023
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0015 0.0037 0.0365
Echinococcus multilocularis calpain 0.0021 0.0074 0.0062
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0135 0.0123
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0015 0.0037 0.0037
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0331 0.4758
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0197 0.277
Leishmania major hypothetical protein, conserved 0.0012 0.0012 0.0036
Echinococcus multilocularis g-protein coupled receptor 0.004 0.0212 0.02
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0212 0.02
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0331 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0053 0.0041
Leishmania major pantothenate kinase subunit, putative 0.0012 0.0012 0.0036
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.0686 0.1421
Loa Loa (eye worm) RecQ helicase 0.0021 0.0078 0.0066
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0265 0.0253
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0212 0.02
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0056 0.0322 0.4604
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0265 0.0265
Loa Loa (eye worm) MH2 domain-containing protein 0.0208 0.1376 0.1366
Brugia malayi hypothetical protein 0.0106 0.067 0.067
Echinococcus multilocularis serotonin receptor 0.004 0.0212 0.02
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0012 0.0012 0.0014
Loa Loa (eye worm) melatonin receptor type 1A 0.004 0.0212 0.02
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0013 0.0023 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0034 0.0167 0.0156
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0056 0.032 0.9633
Onchocerca volvulus 0.004 0.0212 0.02
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0212 0.02
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0331 0.4758
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.0686 0.1421
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0212 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Echinococcus multilocularis biogenic amine (5HT) receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Schistosoma mansoni amine GPCR 0.004 0.0212 0.02
Loa Loa (eye worm) glutamate receptor 2 0.0025 0.0102 0.0091
Trypanosoma cruzi oligopeptidase b 0.0013 0.0023 0.0205
Toxoplasma gondii prolyl endopeptidase 0.0013 0.0023 0.0169
Trypanosoma brucei oligopeptidase b 0.0013 0.0023 0.0205
Onchocerca volvulus 0.004 0.0212 0.02
Brugia malayi Serotonin receptor 0.004 0.0212 0.0212
Schistosoma mansoni coup transcription factor 0.0018 0.0053 0.0041
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0012 0.0043
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0012 0.0012 0.0036
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Leishmania major pyruvate kinase 0.0033 0.0159 0.2204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.1448 1 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0023 0.0011
Schistosoma mansoni agrin 0.0019 0.0061 0.0049
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0189 0.2649
Schistosoma mansoni pyruvate kinase 0.0017 0.0048 0.0036
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0056 0.0322 0.0311
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0159 0.2204
Onchocerca volvulus 0.004 0.0212 0.02
Schistosoma mansoni myosin xvIII 0.004 0.0212 0.02
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0053 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0686 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0076 0.0976
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0121 0.0109
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0331 0.032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0277 0.1853 0.1844
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0061 0.0727
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0014 0.0002
Echinococcus granulosus allatostatin A receptor 0.004 0.0212 0.02
Schistosoma mansoni glutaminase 0.027 0.1811 0.1801
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0053 0.0041
Loa Loa (eye worm) hypothetical protein 0.0063 0.0372 0.0361
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0021 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0011
Onchocerca volvulus 0.004 0.0212 0.02
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0159 0.0147
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0012 0.0014 0.0002
Schistosoma mansoni neuropeptide receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0049
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0212 0.02
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0056 0.032 0.4565
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni organic anion transporter 0.0027 0.0121 0.0109
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0197 0.102
Loa Loa (eye worm) TYRA-2 protein 0.004 0.0212 0.02
Echinococcus multilocularis Smad4 0.0014 0.003 0.0018
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.004 0.0212 0.02
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0053 0.0041
Schistosoma mansoni hypothetical protein 0.0514 0.3506 0.3498
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0056 0.0322 0.4623
Schistosoma mansoni hypothetical protein 0.1448 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0013 0.0023 0.0054
Brugia malayi glutaminase DH11.1 0.027 0.1811 0.1811
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0277 0.1853 0.1844
Brugia malayi Tachykinin-like peptides receptor 99D 0.004 0.0212 0.0212
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.004 0.0212 0.02
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0014 0.0023
Leishmania major DNA damage repair protein, putative 0.0012 0.0014 0.0061
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0056 0.032 0.0308
Mycobacterium ulcerans glutaminase 0.027 0.1811 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Onchocerca volvulus 0.1448 1 1
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0021 0.0076 0.0976
Brugia malayi hypothetical protein 0.0027 0.0121 0.0121
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0014 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.004 0.0212 0.02
Onchocerca volvulus 0.0019 0.0061 0.0049
Echinococcus multilocularis G-protein coupled receptor, putative 0.004 0.0212 0.02
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0014 0.0025
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus multilocularis g protein coupled receptor 0.004 0.0212 0.02
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0014 0.0002
Schistosoma mansoni inhibitor of apoptosis protein 0.1448 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0212 0.02
Echinococcus multilocularis pyruvate kinase 0.0033 0.0159 0.0147
Echinococcus granulosus inhibitor of apoptosis protein 0.1448 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0053 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0014 0.0061
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0014 0.0061
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0021 0.0076 0.0943
Onchocerca volvulus 0.0027 0.0121 0.0109
Echinococcus multilocularis expressed protein 0.0012 0.0014 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0686 0.3757
Echinococcus granulosus serotonin receptor 0.004 0.0212 0.02
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0275 0.1843 0.1834
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0025 0.0102 0.0091
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0053 0.0041
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0021 0.0076 0.0064
Onchocerca volvulus 0.004 0.0212 0.02
Schistosoma mansoni hypothetical protein 0.0514 0.3506 0.3498
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.009 0.0078
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0157 0.0145
Brugia malayi Dopamine receptor protein 1 0.004 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.056 0.3823 0.3815
Loa Loa (eye worm) MH2 domain-containing protein 0.0014 0.003 0.0018
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.1777 0.1767
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.0686 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0275 0.1843 0.1834
Schistosoma mansoni Smad4 0.0014 0.003 0.0018
Echinococcus granulosus dna polymerase kappa 0.0038 0.0197 0.0185
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus granulosus g-protein coupled receptor 0.004 0.0212 0.02
Echinococcus granulosus fmrfamide receptor 0.004 0.0212 0.02
Brugia malayi hypothetical protein 0.056 0.3823 0.3823
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0015 0.0037 0.077
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0061 0.0727
Brugia malayi prolyl oligopeptidase family protein 0.0056 0.0322 0.0322
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0102 0.0091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0053 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0048 0.1126
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0012 0.0014 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0548 0.3742 0.3735
Brugia malayi RNA binding protein 0.0177 0.1158 0.1158
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0053 0.0041
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0074 0.0062
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0014 0.0023
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0159 0.0807
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0212 0.02
Schistosoma mansoni intermediate filament proteins 0.0026 0.0114 0.0102
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0061 0.0727
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0277 0.1853 0.1844
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0014 0.003 0.0018
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0159 0.0309
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0023 0.0205
Leishmania major DNA polymerase kappa, putative 0.0012 0.0014 0.0061
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0012 0.0012 0.0043
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0167 0.1095 0.1084
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni calpain (C02 family) 0.0021 0.0074 0.0062
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0652 0.0652
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0014 0.0061
Echinococcus multilocularis calpain A 0.0057 0.0328 0.0316
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.004 0.0212 0.02
Onchocerca volvulus 0.0012 0.0014 0.0002
Loa Loa (eye worm) RNA binding protein 0.0177 0.1158 0.1148
Onchocerca volvulus Deterin homolog 0.1448 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0053 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0049
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0331 0.4758
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0167 0.1095 0.1084
Brugia malayi hypothetical protein 0.0093 0.0577 0.0577
Trypanosoma brucei antigen, putative 0.0021 0.0074 0.0956
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0012 0.0012 0.0043
Echinococcus multilocularis tar DNA binding protein 0.0177 0.1158 0.1148
Schistosoma mansoni hypothetical protein 0.0434 0.2947 0.2939
Schistosoma mansoni peptide (allatostatin)-like receptor 0.004 0.0212 0.02
Trichomonas vaginalis esterase, putative 0.0109 0.0686 0.3757
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0023 0.0077
Brugia malayi MH2 domain containing protein 0.0014 0.003 0.003
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0014 0.0014
Loa Loa (eye worm) calpain family protein 1 0.0055 0.031 0.0299
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0114 0.0102
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0.0012 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0212 0.02
Schistosoma mansoni ap endonuclease 0.0058 0.0331 0.032
Schistosoma mansoni pyruvate kinase 0.0033 0.0159 0.0147
Trypanosoma brucei DNA polymerase eta, putative 0.0063 0.0372 0.5358
Trypanosoma cruzi kinesin, putative 0.0014 0.0031 0.032
Echinococcus multilocularis hypothetical protein 0.0021 0.0074 0.0062
Onchocerca volvulus 0.003 0.0143 0.0131
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0012 0.0014 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0053 0.0053
Brugia malayi calpain 7 0.0021 0.0074 0.0074
Onchocerca volvulus 0.0021 0.0076 0.0064
Schistosoma mansoni biogenic amine receptor 0.004 0.0212 0.02
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.0686 0.0675
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) TAR-binding protein 0.0177 0.1158 0.1148
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0013 0.0023 0.0169
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0074 0.0956
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Brugia malayi Glutamate receptor 1 precursor 0.0025 0.0102 0.0102
Loa Loa (eye worm) calpain 0.0021 0.0074 0.0062
Brugia malayi calpain family protein 1 0.0055 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0135 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0053 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0014 0.0061
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.5429 0.5424
Plasmodium vivax geranylgeranyltransferase, putative 0.0015 0.0037 0.0365
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0014 0.0002
Echinococcus multilocularis lamin dm0 0.0026 0.0114 0.0102
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0011
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0014 0.0002
Leishmania major pyruvate kinase 0.0033 0.0159 0.2204
Trichomonas vaginalis glutaminase, putative 0.027 0.1811 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0277 0.1853 0.1844
Onchocerca volvulus 0.0106 0.067 0.0659
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0014 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0053 0.0041
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0.0012 0.0036
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0015 0.0037 0.0025
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0061 0.0358 0.0728
Trypanosoma brucei unspecified product 0.0038 0.0197 0.277
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0053 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Trypanosoma cruzi kinesin, putative 0.0014 0.0031 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0053 0.0041
Schistosoma mansoni hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0109
Echinococcus granulosus peptide allatostatin:somatostatin 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0102 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0049
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0004
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0012 0.0036
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.1448 1 1
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0021 0.0076 0.0064
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0212 0.02
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.003 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0014 0.0061
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0013 0.0023 0.0244
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0056 0.032 0.0308
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0012 0.0036
Onchocerca volvulus 0.004 0.0212 0.02
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0143 0.0131
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.0686 0.0675
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0328 0.0316
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0012 0.0014 0.0023
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0014 0.0002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.004 0.0212 0.02
Schistosoma mansoni hypothetical protein 0.0048 0.0265 0.0253
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0012 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0147
Mycobacterium ulcerans lipase LipD 0.0109 0.0686 0.3743
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0076 0.0976
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0212 0.02
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0014 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0053 0.0053
Echinococcus granulosus lamin 0.0026 0.0114 0.0102
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0548 0.3742 0.3735
Plasmodium falciparum pyruvate kinase 0.0033 0.0159 0.4592
Brugia malayi neuropeptide F receptor 0.004 0.0212 0.0212
Echinococcus granulosus follistatin 0.0019 0.0061 0.0049
Echinococcus granulosus acylamino acid releasing enzyme 0.0013 0.0023 0.0011
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0038 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.0686 0.0675
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0015 0.0037 0.0476
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0212 0.02
Echinococcus multilocularis pyruvate kinase 0.0017 0.0048 0.0036
Schistosoma mansoni hypothetical protein 0.0048 0.0265 0.0253
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0265 0.0253
Echinococcus multilocularis agrin 0.0019 0.0061 0.0049
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0056 0.032 0.4565
Loa Loa (eye worm) glutaminase 2 0.027 0.1811 0.1801
Echinococcus granulosus agrin 0.0019 0.0061 0.0049
Brugia malayi RNA recognition motif domain containing protein 0.0177 0.1158 0.1158
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0012 0.0014 0.0023
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0454 0.3091 0.3082
Trypanosoma cruzi lanosterol synthase, putative 0.0061 0.0358 0.5142
Schistosoma mansoni tar DNA-binding protein 0.0177 0.1158 0.1148
Schistosoma mansoni caspase-7 (C14 family) 0.056 0.3823 0.3815
Echinococcus multilocularis lamin 0.0026 0.0114 0.0102
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0013 0.0023 0.0205
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0015 0.0037 0.04
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0212 0.02
Echinococcus multilocularis prolyl endopeptidase 0.0013 0.0023 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.0686 0.1421
Onchocerca volvulus 0.004 0.0212 0.02
Schistosoma mansoni ap endonuclease 0.0058 0.0331 0.032
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0056 0.032 0.0308
Echinococcus granulosus max protein X 0.0454 0.3091 0.3082
Onchocerca volvulus Prolyl endopeptidase homolog 0.0013 0.0023 0.0011
Echinococcus multilocularis calpain family protein 1, d 0.004 0.021 0.0199
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0121 0.0109
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.1448 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0114 0.0102
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0041 0.0214 0.3001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0038 0.0026
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0012 0.0043
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0197 0.1041
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0694 0.4755 1
Brugia malayi calpain family protein 1 0.0055 0.031 0.031
Trypanosoma brucei RNA editing exonuclease 2 0.0012 0.0012 0.0036
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0061 0.0049
Brugia malayi hypothetical protein 0.0012 0.0014 0.0014
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0023 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0013 0.0023 0.0011
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0197 0.277
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0212 0.02
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0021 0.0076 0.0064
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0029 0.0255
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0053 0.0041
Echinococcus multilocularis neuropeptide FF receptor 2 0.004 0.0212 0.02
Echinococcus granulosus bloom syndrome protein 0.0021 0.0078 0.0066
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.004 0.0212 0.02
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0121 0.0109
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0013 0.0023 0.0205
Loa Loa (eye worm) beta-lactamase 0.0109 0.0686 0.0675
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0015 0.0037 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0023 0.0169
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0041
Loa Loa (eye worm) G protein alpha subunit 3 0.0012 0.0014 0.0002
Trypanosoma brucei prolyl oligopeptidase, putative 0.0013 0.0023 0.0205
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0014 0.0002
Echinococcus granulosus pyruvate kinase 0.0017 0.0048 0.0036
Brugia malayi AKH receptor 0.004 0.0212 0.0212
Onchocerca volvulus Protein ultraspiracle homolog 0.0018 0.0053 0.0041
Giardia lamblia Alanyl dipeptidyl peptidase 0.0013 0.0023 0.0357
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0197 0.0197
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0197 0.277
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0159 0.2204
Leishmania major hypothetical protein, conserved 0.0012 0.0012 0.0036
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0367
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0021 0.0076 0.0367
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0159 0.2204
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0197 0.277
Trypanosoma brucei kinesin, putative 0.0014 0.0031 0.032
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0061 0.0061
Echinococcus granulosus glutamate NMDA receptor subunit 0.0025 0.0102 0.0091
Echinococcus granulosus G protein coupled receptor 139 0.004 0.0212 0.02
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0014 0.0002
Brugia malayi hypothetical protein 0.004 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0121 0.0109
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0015 0.0037 0.0476
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0159 0.0828
Loa Loa (eye worm) hypothetical protein 0.004 0.021 0.0199
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.0986 0.0986
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0167 0.1095 0.1084
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0015 0.0037 0.0365
Onchocerca volvulus 0.0012 0.0014 0.0002
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0135 0.0123
Leishmania major kinesin, putative 0.0014 0.0031 0.032
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0029 0.0135 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.02
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0002
Loa Loa (eye worm) glutaminase 0.027 0.1811 0.1801
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0015 0.0037 0.0037
Onchocerca volvulus 0.0027 0.0121 0.0109
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0012 0.0043

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 100 uM Inhibition of COX1 (unknown origin) ChEMBL. 18363350
IC50 (binding) > 100 uM Inhibition of COX2 (unknown origin) ChEMBL. 18363350
IC50 (binding) > 100 uM Inhibition of COX1 (unknown origin) ChEMBL. 18363350
IC50 (binding) > 100 uM Inhibition of COX2 (unknown origin) ChEMBL. 18363350

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.