Detailed information for compound 539088

Basic information

Technical information
  • TDR Targets ID: 539088
  • Name: (5S,8R,9S,10S,13S,14S)-17-hydroxy-17-[(E)-2-i odovinyl]-10,13-dimethyl-2,4,5,6,7,8,9,11,12, 14,15,16-dodecahydro-1H-cyclopenta[a]phenanth ren-3-one
  • MW: 442.374 | Formula: C21H31IO2
  • H donors: 1 H acceptors: 2 LogP: 4.72 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: I/C=C/C1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)CCC(=O)C2
  • InChi: 1S/C21H31IO2/c1-19-8-5-15(23)13-14(19)3-4-16-17(19)6-9-20(2)18(16)7-10-21(20,24)11-12-22/h11-12,14,16-18,24H,3-10,13H2,1-2H3/b12-11+/t14-,16+,17-,18-,19-,20-,21?/m0/s1
  • InChiKey: DWUIOIDQYOFBEC-RELFHSLBSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (5S,8R,9S,10S,13S,14S)-17-hydroxy-17-[(E)-2-iodoethenyl]-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
  • 17-(2-iodovinyl)dihydrotestosterone
  • 129163-98-0
  • (5alpha,17alpha,20E)-17-Hydroxy-21-iodopregn-20-en-3-one
  • 17-Hydroxy-21-iodopregn-20-en-3-one
  • 17-Ipeo
  • E-17alpha-(2-Iodovinyl)-5alpha-dihydrotestosterone
  • IV-Dht
  • Pregn-20-en-3-one, 17-hydroxy-21-iodo-, (5alpha,17alpha,20E)-
  • Z-17alpha-(2-Iodovinyl)-5alpha-dihydrotestosterone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.0288 0.0282
Brugia malayi glutathione reductase 0.0051 0.0097 0.0308
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0394 0.1242 0.1236
Loa Loa (eye worm) hypothetical protein 0.0043 0.0071 0.0195
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.001 0.0321
Echinococcus multilocularis GPCR, family 2 0.0294 0.0907 0.0901
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0057 0.005
Brugia malayi hypothetical protein 0.0044 0.0073 0.023
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0117 0.0316 0.031
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0564 0.3473
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0117 0.0316 0.1158
Loa Loa (eye worm) hypothetical protein 0.0044 0.0073 0.0204
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0394 0.1242 0.1236
Echinococcus multilocularis dnaJ subfamily B 0.3013 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0117 0.0316 0.031
Brugia malayi MAP kinase sur-1 0.0108 0.0288 0.092
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0058 0.0119 0.3758
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.0288 0.9089
Brugia malayi prolyl oligopeptidase family protein 0.0172 0.05 0.16
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0048 0.0086 0.0529
Echinococcus granulosus lamin 0.0084 0.0207 0.02
Echinococcus multilocularis lamin 0.0084 0.0207 0.02
Echinococcus granulosus zinc finger protein 0.0073 0.0171 0.0164
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.001 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.0517 0.0511
Loa Loa (eye worm) hypothetical protein 0.0273 0.0839 0.2667
Echinococcus multilocularis calpain A 0.0068 0.0152 0.0146
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0817 0.2656 1
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.001 0.0001
Brugia malayi jmjC domain containing protein 0.0083 0.0204 0.0648
Loa Loa (eye worm) CXXC zinc finger family protein 0.0212 0.0633 0.2005
Loa Loa (eye worm) histone methyltransferase 0.0065 0.0145 0.0433
Schistosoma mansoni bromodomain containing protein 0.0025 0.0011 0.0009
Brugia malayi Bromodomain containing protein 0.0247 0.075 0.2402
Loa Loa (eye worm) hypothetical protein 0.0064 0.0141 0.0423
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0112 0.0301 0.0295
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.0143 0.0137
Brugia malayi prolyl oligopeptidase family protein 0.0058 0.0119 0.0376
Echinococcus multilocularis lamin dm0 0.0084 0.0207 0.02
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0112 0.0301 0.0295
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.001 0.0001
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.0288 0.1052
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0097 0.0091
Schistosoma mansoni smad1 5 8 and 0.0033 0.0036 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Echinococcus granulosus tumor protein p63 0.0688 0.2226 0.222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Echinococcus granulosus lysosomal alpha glucosidase 0.0177 0.0517 0.0511
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0119 0.0118
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0036 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.015 0.4585
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.015 0.2006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0394 0.1242 0.124
Loa Loa (eye worm) hypothetical protein 0.0955 0.3119 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0294 0.0907 0.0901
Echinococcus granulosus mixed lineage leukemia protein mll 0.0053 0.0101 0.0095
Brugia malayi HSF-type DNA-binding domain containing protein 0.0108 0.0286 0.0912
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0061 0.0055
Schistosoma mansoni calpain-7 (C02 family) 0.0029 0.0021 0.002
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.001 0.0008
Brugia malayi intermediate filament protein 0.0084 0.0207 0.0659
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0025 0.001 0.0061
Schistosoma mansoni cpg binding protein 0.0212 0.0633 0.0632
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0317 0.8342
Echinococcus granulosus expressed protein 0.0051 0.0096 0.009
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0117 0.0316 1
Echinococcus granulosus roundabout 2 0.0031 0.0028 0.0021
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0117 0.0316 1
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0207 0.0634
Schistosoma mansoni hypothetical protein 0.0117 0.0316 0.0315
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0314 0.0974 0.3102
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0012 0.0072
Toxoplasma gondii cathepsin CPC1 0.0817 0.2656 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0091 0.2879
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.0288 0.1052
Echinococcus multilocularis smad 0.0033 0.0036 0.0029
Schistosoma mansoni jumonji/arid domain-containing protein 0.0083 0.0204 0.0202
Echinococcus multilocularis isocitrate dehydrogenase 0.0117 0.0316 0.031
Echinococcus granulosus lysine specific demethylase 5A 0.0083 0.0204 0.0197
Entamoeba histolytica heat shock transcription factor, putative 0.0108 0.0286 0.8395
Schistosoma mansoni lamin 0.0084 0.0207 0.0206
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0101 0.01
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.013 0.0361 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0136 0.4302
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0849 0.5227
Schistosoma mansoni glutaminase 0.0302 0.0937 0.0936
Schistosoma mansoni intermediate filament proteins 0.0084 0.0207 0.0206
Giardia lamblia Encystation-specific protease 0.0312 0.0968 0.3621
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0394 0.1242 0.3978
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0172 0.05 0.5518
Schistosoma mansoni calpain-7 (C02 family) 0.0029 0.0021 0.002
Echinococcus multilocularis calpain family protein 1, d 0.0045 0.0077 0.0071
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0117 0.0316 0.0315
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0076 0.024
Brugia malayi Latrophilin receptor protein 2 0.0294 0.0907 0.2906
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0849 0.5227
Schistosoma mansoni hypothetical protein 0.0294 0.0907 0.0906
Echinococcus multilocularis survival motor neuron protein 1 0.0955 0.3119 0.3114
Echinococcus granulosus geminin 0.0892 0.2909 0.2905
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0117 0.0316 0.031
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0036 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0849 0.5227
Leishmania major hypothetical protein, conserved 0.0025 0.001 0.001
Brugia malayi MH2 domain containing protein 0.0033 0.0036 0.011
Entamoeba histolytica heat shock transcription factor, putative 0.0108 0.0286 0.8395
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0057 0.0351
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0104 0.0103
Echinococcus granulosus Smad4 0.0033 0.0036 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0449 0.1426 0.1425
Echinococcus multilocularis cpg binding protein 0.023 0.0693 0.0687
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0817 0.2656 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0086 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0086 0.0529
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0177 0.0517 0.1632
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0394 0.1242 0.1236
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Echinococcus multilocularis musashi 0.0084 0.0207 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0288 0.1775
Echinococcus granulosus histone lysine methyltransferase setb 0.0058 0.0119 0.0113
Entamoeba histolytica hypothetical protein 0.0117 0.0316 0.9315
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0064 0.0141 0.0423
Schistosoma mansoni hypothetical protein 0.0195 0.0577 0.0576
Entamoeba histolytica hypothetical protein 0.0117 0.0316 0.9315
Loa Loa (eye worm) isocitrate dehydrogenase 0.0117 0.0316 0.0986
Loa Loa (eye worm) glutaminase 0.0302 0.0937 0.2982
Entamoeba histolytica hypothetical protein 0.0117 0.0316 0.9315
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.0288 0.0896
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.001 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0057 0.1803
Schistosoma mansoni hypothetical protein 0.0048 0.0086 0.0084
Loa Loa (eye worm) TAR-binding protein 0.0383 0.1205 0.3846
Schistosoma mansoni hypothetical protein 0.3013 1 1
Leishmania major cathepsin L-like protease 0.0063 0.0136 0.4119
Schistosoma mansoni zinc finger protein 0.0073 0.0171 0.0169
Schistosoma mansoni nephrin 0.0024 0.0007 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0065 0.0145 0.0138
Mycobacterium ulcerans glutaminase 0.0302 0.0937 1
Schistosoma mansoni alpha glucosidase 0.0039 0.0057 0.0056
Leishmania major cathepsin L-like protease 0.0063 0.0136 0.4119
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0117 0.0316 0.8299
Toxoplasma gondii thioredoxin reductase 0.0051 0.0097 0.0331
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0288 0.9117
Loa Loa (eye worm) calpain family protein 1 0.0064 0.0141 0.0423
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.0317 0.8342
Onchocerca volvulus 0.0084 0.0207 0.2274
Brugia malayi Calcitonin receptor-like protein seb-1 0.0928 0.3028 0.9708
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0051 0.0096 0.0304
Echinococcus multilocularis microtubule associated protein 2 0.14 0.4606 0.4603
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0058 0.0119 0.3758
Onchocerca volvulus 0.0286 0.0883 0.9753
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0207 0.0659
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0057 0.005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0057 0.0178
Brugia malayi manba-prov protein 0.0059 0.0124 0.0393
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0025 0.001 0.0311
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0928 0.3028 0.9708
Echinococcus multilocularis Smad4 0.0033 0.0036 0.0029
Brugia malayi Glycosyl hydrolases family 31 protein 0.0177 0.0517 0.1655
Echinococcus multilocularis zinc finger protein 0.0073 0.0171 0.0164
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0394 0.1242 0.3962
Onchocerca volvulus Huntingtin homolog 0.0273 0.0839 0.927
Onchocerca volvulus 0.0212 0.0633 0.6989
Schistosoma mansoni hypothetical protein 0.0892 0.2909 0.2908
Schistosoma mansoni cpg binding protein 0.023 0.0693 0.0692
Trypanosoma brucei ISWI complex protein 0.0048 0.0086 0.2709
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.015 0.0149
Brugia malayi RNA binding protein 0.0383 0.1205 0.3862
Loa Loa (eye worm) RNA binding protein 0.0383 0.1205 0.3846
Trichomonas vaginalis chaperonin, putative 0.0025 0.001 0.0061
Toxoplasma gondii isocitrate dehydrogenase 0.0117 0.0316 0.1158
Leishmania major cathepsin L-like protease 0.0063 0.0136 0.4119
Mycobacterium tuberculosis Probable reductase 0.0117 0.0317 0.8342
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0058 0.0119 0.0412
Schistosoma mansoni tar DNA-binding protein 0.0383 0.1205 0.1204
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0097 0.0282
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.001 0.0321
Trypanosoma cruzi ISWI complex protein 0.0048 0.0086 0.2709
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Schistosoma mansoni survival motor neuron protein 0.0195 0.0577 0.0576
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0057 0.0152
Loa Loa (eye worm) hypothetical protein 0.0273 0.0839 0.2667
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.0288 0.9117
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0051 0.0096 0.0327
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0058 0.0119 0.3758
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.0288 0.9117
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0288 0.0287
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0061 0.0055
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0064 0.014 0.042
Onchocerca volvulus Tyrosine kinase homolog 0.0293 0.0905 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0056 0.0149
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.0849 0.2699
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0025 0.001 0.0311
Echinococcus multilocularis roundabout 2 0.0031 0.0028 0.0021
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0051 0.0096 0.0327
Schistosoma mansoni hypothetical protein 0.0065 0.0141 0.014
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2593 0.8595 0.8594
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.0288 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0508 0.1624 1
Trypanosoma brucei trypanothione reductase 0.0051 0.0097 0.3081
Brugia malayi RNA recognition motif domain containing protein 0.0383 0.1205 0.3862
Brugia malayi calpain family protein 1 0.0064 0.0141 0.0449
Loa Loa (eye worm) PHD-finger family protein 0.0065 0.0141 0.0423
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.015 0.0144
Schistosoma mansoni jumonji domain containing protein 0.0065 0.0143 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Loa Loa (eye worm) transcription factor SMAD2 0.0482 0.1539 0.4917
Echinococcus granulosus tar DNA binding protein 0.0383 0.1205 0.1199
Brugia malayi PHD-finger family protein 0.009 0.0227 0.0722
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0086 0.0529
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0312 0.0968 0.3621
Brugia malayi hypothetical protein 0.0025 0.001 0.0028
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.0288 0.0282
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0001
Brugia malayi hypothetical protein 0.0955 0.3119 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0057 0.0351
Schistosoma mansoni hypothetical protein 0.0634 0.2046 0.2045
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0053 0.0101 0.0095
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0057 0.0351
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0394 0.1242 0.124
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0058 0.0119 0.0117
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0294 0.0907 0.0901
Loa Loa (eye worm) hypothetical protein 0.0145 0.0412 0.1293
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.001 0.0001
Trichomonas vaginalis glycoside hydrolase, putative 0.0292 0.0902 0.5551
Loa Loa (eye worm) hypothetical protein 0.0221 0.0665 0.2108
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0537 0.3305
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0312 0.0968 0.3621
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0058
Loa Loa (eye worm) hypothetical protein 0.0041 0.0061 0.0166
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0036 0.0083
Entamoeba histolytica hypothetical protein 0.0031 0.0029 0.0587
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0053 0.0104 0.0097
Loa Loa (eye worm) hypothetical protein 0.0045 0.0077 0.0217
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0086 0.0529
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0027 0.0026
Trypanosoma cruzi ISWI complex protein 0.0048 0.0086 0.2709
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0849 0.5227
Trichomonas vaginalis helicase, putative 0.0048 0.0086 0.0529
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.0288 0.9117
Brugia malayi MH2 domain containing protein 0.0033 0.0036 0.011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0057 0.1435
Onchocerca volvulus 0.0102 0.0268 0.2948
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.2525 0.8369 0.8369
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.001 0.0321
Schistosoma mansoni microtubule-associated protein tau 0.14 0.4606 0.4606
Onchocerca volvulus 0.0101 0.0262 0.2887
Brugia malayi Thioredoxin reductase 0.0051 0.0097 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0036 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0104 0.0103
Leishmania major trypanothione reductase 0.0051 0.0097 0.2859
Echinococcus granulosus survival motor neuron protein 1 0.0955 0.3119 0.3114
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0071 0.0222
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0057 0.0351
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.013 0.0361 1
Brugia malayi jmjC domain containing protein 0.0065 0.0143 0.0455
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0036 0.0029
Brugia malayi TAR-binding protein 0.0383 0.1205 0.3862
Plasmodium vivax glutathione reductase, putative 0.0051 0.0097 0.0331
Schistosoma mansoni bromodomain containing protein 0.021 0.0628 0.0626
Loa Loa (eye worm) bromodomain containing protein 0.0055 0.011 0.0324
Brugia malayi hypothetical protein 0.0039 0.0057 0.0177
Loa Loa (eye worm) MH2 domain-containing protein 0.0482 0.1539 0.4917
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0057 0.0351
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0025 0.001 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0288 0.1775
Schistosoma mansoni myst-related protein 0.0031 0.0029 0.0028
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0817 0.2656 1
Schistosoma mansoni hypothetical protein 0.0173 0.0505 0.0504
Brugia malayi Isocitrate dehydrogenase 0.0117 0.0316 0.101
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0312 0.0968 0.3621
Loa Loa (eye worm) Smad1 0.0033 0.0036 0.0083
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.0288 0.9089
Schistosoma mansoni cpg binding protein 0.023 0.0693 0.0692
Echinococcus granulosus cpg binding protein 0.023 0.0693 0.0687
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0817 0.2656 1
Brugia malayi calpain family protein 1 0.0064 0.0141 0.0449
Echinococcus multilocularis geminin 0.0892 0.2909 0.2905
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.0849 0.2718
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0618
Leishmania major hypothetical protein, conserved 0.0048 0.0086 0.2475
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0097 0.3081
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0383 0.1205 0.3846
Echinococcus granulosus twitchin 0.0025 0.001 0.0003
Loa Loa (eye worm) beta-glucuronidase 0.0059 0.0124 0.0367
Schistosoma mansoni smad1 5 8 and 0.0033 0.0036 0.0034
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0051 0.0096 0.0327
Toxoplasma gondii histone lysine methyltransferase SET1 0.0408 0.1291 0.4839
Trichomonas vaginalis beta-mannosidase, putative 0.0059 0.0124 0.0763
Schistosoma mansoni beta-mannosidase 0.0059 0.0124 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Plasmodium falciparum glutathione reductase 0.0051 0.0097 0.0331
Entamoeba histolytica hypothetical protein 0.0117 0.0316 0.9315
Entamoeba histolytica beta-galactosidase, putative 0.0123 0.0339 1
Plasmodium falciparum thioredoxin reductase 0.0051 0.0097 0.0331
Brugia malayi F/Y-rich N-terminus family protein 0.0071 0.0162 0.0514
Toxoplasma gondii TIM10 family protein, putative 0.0051 0.0096 0.0327
Loa Loa (eye worm) hypothetical protein 0.012 0.0327 0.102
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0025 0.001 0.0003
Schistosoma mansoni hypothetical protein 0.0892 0.2909 0.2908
Schistosoma mansoni jumonji/arid domain-containing protein 0.0083 0.0204 0.0202
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.0288 0.0282
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0294 0.0907 0.2887
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.0517 0.0511
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.013 0.0361 1
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0071 0.0222
Schistosoma mansoni Smad4 0.0033 0.0036 0.0034
Toxoplasma gondii cathepsin CPC2 0.0312 0.0968 0.3621
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0036 0.0083
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0141 0.014
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0817 0.2656 0.2655
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0064 0.014 0.0446
Brugia malayi glutaminase DH11.1 0.0302 0.0937 0.3001
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0817 0.2656 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0083 0.0204 0.0623
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0065 0.0145 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0072
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0057 0.0351
Echinococcus granulosus smad 0.0033 0.0036 0.0029
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0071 0.0222
Schistosoma mansoni tar DNA-binding protein 0.0383 0.1205 0.1204
Mycobacterium tuberculosis Probable oxidoreductase 0.013 0.0361 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.015 0.0144
Schistosoma mansoni tar DNA-binding protein 0.0383 0.1205 0.1204
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0058 0.0119 0.0113
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0036 0.0029
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.0152 0.0151
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0394 0.1242 0.124
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0172 0.05 0.0494
Brugia malayi latrophilin 2 splice variant baaae 0.0634 0.2046 0.656
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0048 0.0086 0.0529
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0317 0.8342
Loa Loa (eye worm) hypothetical protein 0.0108 0.0286 0.0888
Brugia malayi Smad1 0.0033 0.0036 0.011
Plasmodium falciparum zinc finger protein, putative 0.0031 0.0029 0.0073
Brugia malayi hypothetical protein 0.0039 0.0057 0.0177
Schistosoma mansoni alpha-glucosidase 0.0152 0.0435 0.0434
Schistosoma mansoni hypothetical protein 0.0294 0.0907 0.0906
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0172 0.05 0.0499
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.0262 0.0261
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0068 0.0152 0.0146
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0312 0.0968 0.3621
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0097 0.0331
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0053 0.0101 0.0095
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0108 0.0286 0.3146
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.001 0.0008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0288 0.9117
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.015 0.0149
Loa Loa (eye worm) glutaminase 2 0.0302 0.0937 0.2982
Onchocerca volvulus Huntingtin homolog 0.0273 0.0839 0.927
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0459 0.1461 0.146
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0199 0.059 0.0584
Loa Loa (eye worm) hypothetical protein 0.0101 0.0262 0.0812
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Toxoplasma gondii preprocathepsin c precursor, putative 0.0817 0.2656 1
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.0531 0.5865
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0294 0.0907 0.0901
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0143 0.0137
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0026 0.0011 0.0005
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0071 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0564 0.3473
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0143 0.0137
Schistosoma mansoni tar DNA-binding protein 0.0383 0.1205 0.1204
Loa Loa (eye worm) glutathione reductase 0.0051 0.0097 0.0282
Brugia malayi MH2 domain containing protein 0.0482 0.1539 0.4931
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0928 0.3028 0.9707
Schistosoma mansoni hypothetical protein 0.0294 0.0907 0.0906
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0051 0.0096 0.0095
Trichomonas vaginalis glutaminase, putative 0.0302 0.0937 0.5769
Echinococcus granulosus fetal alzheimer antigen falz 0.0083 0.0202 0.0195
Loa Loa (eye worm) hypothetical protein 0.0058 0.0119 0.0353
Onchocerca volvulus 0.0195 0.0577 0.6369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0058
Schistosoma mansoni tar DNA-binding protein 0.0383 0.1205 0.1204
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0136 0.4302
Schistosoma mansoni alpha-glucosidase 0.0152 0.0435 0.0434
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0294 0.0907 0.2906
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0083 0.0202 0.02
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0117 0.0316 0.031
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0044 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0394 0.1242 0.1236
Schistosoma mansoni hypothetical protein 0.0294 0.0907 0.0906
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0294 0.0907 0.0901
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.001 0.0027
Echinococcus granulosus intermediate filament protein 0.0084 0.0207 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0195 0.0577 0.1846
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0119 0.0118
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0071 0.023
Loa Loa (eye worm) calpain family protein 1 0.0045 0.0077 0.0217
Trypanosoma brucei protein kinase, putative 0.0108 0.0288 0.9117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0086 0.0529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Schistosoma mansoni lamin 0.0084 0.0207 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Echinococcus granulosus lamin dm0 0.0084 0.0207 0.02
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.0317 0.8342
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0117 0.0316 0.031
Brugia malayi hypothetical protein 0.0117 0.0316 0.1009
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0136 0.4302
Loa Loa (eye worm) latrophilin receptor protein 2 0.0294 0.0907 0.2887
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0057 0.0178
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0117 0.0316 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0083 0.0202 0.0195
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0051 0.0096 0.0278
Schistosoma mansoni smad1 5 8 and 0.0033 0.0036 0.0034
Schistosoma mansoni hypothetical protein 0.0043 0.0071 0.0069
Schistosoma mansoni cell adhesion molecule 0.0026 0.0011 0.001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0057 0.1435
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0207 0.0634
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0117 0.0316 1
Echinococcus granulosus calpain A 0.0068 0.0152 0.0146
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0058 0.0119 0.3557
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0288 0.1775
Brugia malayi hypothetical protein 0.0273 0.0839 0.2687
Schistosoma mansoni myst-related protein 0.0031 0.0029 0.0028
Toxoplasma gondii isocitrate dehydrogenase 0.0117 0.0316 0.1158
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0068 0.0152 0.0146
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0058 0.0119 0.0112
Brugia malayi CXXC zinc finger family protein 0.0212 0.0633 0.2026
Brugia malayi Beta-glucuronidase precursor 0.0059 0.0124 0.0393
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0057 0.1803
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0531 0.3272
Echinococcus granulosus microtubule associated protein 2 0.14 0.4606 0.4603
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0044 0.0037
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0053 0.0101 0.0095
Echinococcus granulosus GPCR family 2 0.0294 0.0907 0.0901
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.0316 0.0315
Echinococcus multilocularis expressed protein 0.0051 0.0096 0.009
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.015 0.0531
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.0152 0.0151
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0199 0.059 0.0584
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0071 0.023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.0316 0.031
Trichomonas vaginalis hypothetical protein 0.0026 0.0012 0.0072
Onchocerca volvulus 0.0084 0.0207 0.2274
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0005
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0043 0.0071 0.023
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.0317 0.8342
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.0316 0.031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0086 0.0529
Brugia malayi MH1 domain containing protein 0.0033 0.0036 0.011
Trypanosoma brucei glucosidase, putative 0.0039 0.0057 0.1803
Loa Loa (eye worm) hypothetical protein 0.0634 0.2046 0.655
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0172 0.05 0.0494
Loa Loa (eye worm) hypothetical protein 0.0928 0.3028 0.9707
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0136 0.4302
Loa Loa (eye worm) hypothetical protein 0.0084 0.0207 0.0634
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0118 0.3725
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0288 0.1775
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0057 0.0351
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0974 0.312
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0849 0.5227
Echinococcus multilocularis tar DNA binding protein 0.0383 0.1205 0.1199
Loa Loa (eye worm) hypothetical protein 0.0039 0.0056 0.0149
Loa Loa (eye worm) prolyl oligopeptidase 0.0172 0.05 0.1577
Onchocerca volvulus 0.0045 0.0077 0.0838
Echinococcus granulosus Dipeptidyl peptidase 9 0.0058 0.0119 0.0112
Loa Loa (eye worm) hypothetical protein 0.0045 0.0077 0.0217
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0097 0.0091
Brugia malayi isocitrate dehydrogenase 0.0117 0.0316 0.101
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0076 0.0214
Schistosoma mansoni smad 0.0033 0.0036 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0086 0.0529
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0057 0.0351
Echinococcus multilocularis tumor protein p63 0.0688 0.2226 0.222
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0117 0.0316 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0117 0.0316 0.1158
Brugia malayi MH1 domain containing protein 0.0033 0.0036 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0136 0.4302
Schistosoma mansoni zinc finger protein 0.0048 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0127 0.0352 0.1099
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0057 0.1539
Trichomonas vaginalis beta-galactosidase, putative 0.0183 0.0537 0.3305
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0057 0.0351
Brugia malayi Bromodomain containing protein 0.012 0.0326 0.1042
Echinococcus granulosus methyl CpG binding domain protein 2 0.0053 0.0104 0.0097
Entamoeba histolytica heat shock transcription factor, putative 0.0108 0.0286 0.8395
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0849 0.5227
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0058 0.0119 0.3758

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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