Detailed information for compound 629486

Basic information

Technical information
  • TDR Targets ID: 629486
  • Name: N-[3-[(4-ethoxyphenyl)-(4-methylpiperazin-1-y l)methyl]-4,5-dimethylthiophen-2-yl]furan-2-c arboxamide
  • MW: 453.597 | Formula: C25H31N3O3S
  • H donors: 1 H acceptors: 1 LogP: 4.62 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)C(c1c(sc(c1C)C)NC(=O)c1ccco1)N1CCN(CC1)C
  • InChi: 1S/C25H31N3O3S/c1-5-30-20-10-8-19(9-11-20)23(28-14-12-27(4)13-15-28)22-17(2)18(3)32-25(22)26-24(29)21-7-6-16-31-21/h6-11,16,23H,5,12-15H2,1-4H3,(H,26,29)
  • InChiKey: YRLRKOSBTQXEFW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[3-[(4-ethoxyphenyl)-(4-methylpiperazin-1-yl)methyl]-4,5-dimethyl-2-thienyl]furan-2-carboxamide
  • N-[3-[(4-ethoxyphenyl)-(4-methyl-1-piperazinyl)methyl]-4,5-dimethyl-2-thienyl]-2-furancarboxamide
  • N-[3-[(4-ethoxyphenyl)-(4-methylpiperazin-1-yl)methyl]-4,5-dimethyl-2-thienyl]-2-furamide
  • N-[3-[(4-ethoxyphenyl)-(4-methylpiperazin-1-yl)methyl]-4,5-dimethyl-thiophen-2-yl]furan-2-carboxamide
  • T5472941

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0095 0.0557 0.0903
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 0.0008 0.001 0.001
Echinococcus granulosus disco interacting protein 2 0.0008 0.001 0.0027
Brugia malayi Pre-SET motif family protein 0.0238 0.1465 0.3672
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0085 0.0221
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0189 0.0471
Schistosoma mansoni hypothetical protein 0.0008 0.001 0.0017
Onchocerca volvulus 0.0028 0.0139 0.0831
Brugia malayi latrophilin 2 splice variant baaae 0.01 0.0593 0.1486
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0166 0.2181
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0031 0.0158 0.2076
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0189 0.0306
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0722 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0039
Echinococcus granulosus tyrosine protein kinase Src42A 0.0007 0.0006 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0225 0.0559
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0166 0.0988
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0189 0.0189
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Echinococcus granulosus thyroid hormone receptor alpha 0.0009 0.0019 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0158 0.0396
Brugia malayi nuclear receptor RXR 0.001 0.0026 0.0065
Schistosoma mansoni hypothetical protein 0.0023 0.0106 0.0172
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0187 0.2478
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.0722 0.1788
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0031 0.0158 0.0396
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0085 0.0213
Onchocerca volvulus 0.0095 0.0557 0.3332
Echinococcus multilocularis cpg binding protein 0.0032 0.0163 0.0163
Schistosoma mansoni neutral sphingomyelinase 0.0008 0.0013 0.0021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0009 0.0019 0.0111
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0013 0.0033
Trypanosoma cruzi ISWI complex protein 0.0017 0.0068 0.0151
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0163 0.0403
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0059 0.0329 0.0826
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0031 0.0158 0.2076
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.0722 0.0722
Schistosoma mansoni hypothetical protein 0.01 0.0593 0.0961
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0158 0.0385
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0085 0.0138
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0225 0.0559
Plasmodium vivax long-chain fatty acid CoA ligase, putative 0.0008 0.001 0.0459
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0187 0.046
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0187 0.0466
Echinococcus multilocularis GPCR, family 2 0.0046 0.0253 0.0253
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0031 0.0158 0.0396
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0023 0.0023
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0058 0.0674
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Echinococcus multilocularis survival motor neuron protein 1 0.0464 0.289 0.289
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0112 0.0282
Loa Loa (eye worm) histone methyltransferase 0.001 0.0023 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0722 0.117
Schistosoma mansoni cpg binding protein 0.0028 0.0139 0.0225
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0085 0.0213
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0081 0.0211
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0166 0.1197
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0031 0.0158 0.0391
Echinococcus multilocularis disco interacting protein 2 0.0008 0.001 0.001
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0722 0.1809
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0031 0.0158 0.0385
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0031 0.0158 0.0371
Echinococcus granulosus dnaJ subfamily B 0.0404 0.2514 0.6542
Leishmania major acetyl-CoA synthetase, putative 0.0031 0.0158 0.0391
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0179 0.0179
Schistosoma mansoni nuclear receptor nhr-48 0.0009 0.0019 0.003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0225 0.0566
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0013 0.0039
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0085 0.0138
Loa Loa (eye worm) hypothetical protein 0.0085 0.0499 0.1251
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0847 0.1372
Echinococcus granulosus GPCR family 2 0.0046 0.0253 0.0658
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0008 0.0013 0.0007
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0031 0.0158 0.0391
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0189 0.1126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0847 0.1372
Echinococcus multilocularis geminin 0.0517 0.3224 0.3224
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0031 0.0158 0.0391
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0085 0.0138
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0008 0.0013 0.0077
Loa Loa (eye worm) SRC-1 0.0007 0.0006 0.0014
Brugia malayi Tyrosine-protein kinase abl-1 0.0092 0.0539 0.1352
Plasmodium vivax SET domain protein, putative 0.0035 0.0179 0.7967
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0039
Onchocerca volvulus 0.0009 0.0019 0.0111
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0013 0.0013
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0187 0.0443
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0187 0.135
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0246 0.0616
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0031 0.0158 0.0391
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0007 0.0006 0.0006
Onchocerca volvulus 0.0271 0.1673 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.0626 0.1569
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0166 0.1197
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0189 0.0491
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Schistosoma mansoni patched 1 0.0045 0.0246 0.0398
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0166 0.0988
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0847 0.1372
Leishmania major acetyl-CoA synthetase, putative 0.0031 0.0158 0.0391
Brugia malayi hypothetical protein 0.0008 0.001 0.0026
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0013 0.0582
Toxoplasma gondii MAPEG family protein 0.0225 0.1383 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0225 0.1382 0.3596
Trypanosoma brucei ISWI complex protein 0.0017 0.0068 0.0816
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0284 0.074
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0085 0.0221
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0013 0.0007
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0184 0.048
Brugia malayi nuclear hormone receptor 0.002 0.0085 0.0213
Entamoeba histolytica hypothetical protein 0.0036 0.0184 0.2444
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Brugia malayi nuclear receptor NHR-88 0.002 0.0085 0.0213
Schistosoma mansoni carbon catabolite repressor protein 0.0008 0.0013 0.0021
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0009 0.0019 0.003
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0013 0.0582
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.0722 0.1882
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0019 0.003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0189 0.0465
Brugia malayi AMP-binding enzyme family protein 0.0008 0.001 0.0026
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0284 0.0461
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.0026 0.0026
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0031 0.0158 0.0371
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0158 0.0391
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0085 0.0138
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0085 0.0138
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Brugia malayi hypothetical protein 0.0464 0.289 0.7243
Trichomonas vaginalis AMP dependent ligase, putative 0.0008 0.001 0.006
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Brugia malayi Bromodomain containing protein 0.0043 0.0232 0.0581
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0284 0.0461
Schistosoma mansoni hypothetical protein 0.0517 0.3224 0.5225
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0085 0.0213
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0187 0.2478
Echinococcus granulosus zinc finger protein 0.0024 0.0109 0.0284
Mycobacterium tuberculosis Probable exported protein 0.0008 0.0013 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0085 0.0213
Onchocerca volvulus 0.0031 0.0158 0.0945
Brugia malayi Nuclear hormone receptor E75 0.0009 0.0019 0.0047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0085 0.0221
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0333 0.0853
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.0722 0.1882
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.0722 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0007
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0187 0.0187
Brugia malayi CXXC zinc finger family protein 0.0028 0.0139 0.0349
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0187 0.046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0085 0.0138
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0085 0.0213
Loa Loa (eye worm) TK/ABL protein kinase 0.0225 0.1382 0.3463
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0189 0.0491
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0008 0.0013 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0008 0.001 0.0026
Plasmodium vivax acyl-CoA synthetase, putative 0.0008 0.001 0.0459
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0983 0.6171 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0065
Brugia malayi ecdysteroid receptor 0.002 0.0085 0.0213
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Echinococcus granulosus microsomal glutathione S transferase 3 0.0225 0.1383 0.36
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0225 0.0585
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.0625
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0085 0.0221
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Plasmodium vivax exodeoxyribonuclease III, putative 0.0008 0.0013 0.0582
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0039
Brugia malayi cDNA sequence BC018371 0.0008 0.001 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0847 0.0847
Schistosoma mansoni zinc finger protein 0.0024 0.0109 0.0177
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0112 0.1433
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0106 0.0267
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0106 0.0626 0.8652
Loa Loa (eye worm) inositol-1 0.0036 0.0187 0.0468
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0007
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0722 1
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0166 0.0988
Brugia malayi nuclear receptor NHR-88 0.0009 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.013 0.0339
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0058 0.0674
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0058 0.0058
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.001 0.0026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0013 0.0007
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0009 0.0019 0.0019
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0085 0.0085
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0329 0.0857
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0013 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0008 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0033
Plasmodium vivax acetyl-CoA synthetase, putative 0.0031 0.0158 0.7037
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 4 0.0008 0.001 0.001
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0064 0.014
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0007
Leishmania major RNA-editing complex protein MP100, putative 0.0008 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0009 0.0019 0.003
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0179 0.029
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0064 0.0141
Brugia malayi hypothetical protein 0.0009 0.0019 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0166 0.0988
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0008 0.001 0.006
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Echinococcus granulosus FTZ F1 alpha 0.002 0.0085 0.0221
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0189 0.1126
Echinococcus granulosus AMP dependent ligase 0.0008 0.001 0.0027
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0058 0.0152
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0225 1
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0112 0.0293
Onchocerca volvulus 0.0031 0.0158 0.0945
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0058 0.0125
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0158 0.0391
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0085 0.0213
Brugia malayi isocitrate dehydrogenase 0.0016 0.0058 0.0146
Leishmania major 4-coumarate:coa ligase-like protein 0.0031 0.0158 0.0391
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.001 0.0075
Schistosoma mansoni tyrosine kinase 0.0222 0.1362 0.2206
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0009 0.0019 0.0047
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0225 0.3011
Onchocerca volvulus 0.0031 0.0158 0.0945
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0722 0.4315
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0065
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0013 0.0582
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0023 0.006
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0225 1
Schistosoma mansoni hypothetical protein 0.0044 0.0235 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0246 0.1467
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0324 0.2343
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0085 0.0213
Loa Loa (eye worm) MBCTL1 0.0059 0.0329 0.0826
Echinococcus granulosus survival motor neuron protein 1 0.0464 0.289 0.7521
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0007 0.0006 0.0015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0147 0.0886 0.2221
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0081 0.0131
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0085 0.0507
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0085 0.0213
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0615 0.3842 1
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0008 0.0013 0.0077
Schistosoma mansoni hypothetical protein 0.0046 0.0253 0.041
Schistosoma mansoni synaptojanin 0.0008 0.0013 0.0021
Toxoplasma gondii hypothetical protein 0.0008 0.001 0.0075
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0187 0.1115
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Trichomonas vaginalis AMP dependent ligase, putative 0.0008 0.001 0.006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.0253 0.0658
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0065
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0112 0.0266
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0031 0.0158 0.0391
Brugia malayi AMP-binding enzyme family protein 0.0638 0.399 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0007 0.0006 0.0015
Schistosoma mansoni cpg binding protein 0.0032 0.0163 0.0264
Echinococcus granulosus cpg binding protein 0.0032 0.0163 0.0424
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0085 0.0085
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0085 0.0214
Giardia lamblia Inositol 5-phosphatase 4 0.0008 0.0013 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.03 0.0487
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0225 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0058 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0085 0.0213
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0007 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0158 0.0391
Brugia malayi Pre-SET motif family protein 0.0035 0.0179 0.0449
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.0607 0.3792 1
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0085 0.0138
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0189 0.0473
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0147 0.0886 0.2221
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0225 1
Brugia malayi hypothetical protein 0.0036 0.0184 0.0462
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0112 0.5
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0031 0.0158 0.0385
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0008 0.001 0.006
Schistosoma mansoni ap endonuclease 0.0042 0.0225 0.0364
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0031 0.0158 0.0391
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0085 0.0213
Schistosoma mansoni cript-related 0.0008 0.0013 0.0021
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0085 0.0085
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.001 0.0075
Toxoplasma gondii type I fatty acid synthase, putative 0.0008 0.001 0.0075
Brugia malayi Inositol-1 0.0036 0.0187 0.0468
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0847 0.0847
Schistosoma mansoni tyrosine kinase 0.0007 0.0006 0.0009
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0189 0.2505
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0058 0.2594
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0225 0.0563
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0085 0.0085
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0013 0.0007
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0158 0.0391
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0085 0.0085
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0008 0.001 0.006
Echinococcus granulosus Niemann Pick C1 protein 0.0151 0.0912 0.2374
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0638 0.399 1
Brugia malayi Nuclear hormone receptor E75 0.0009 0.0019 0.0047
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0329 0.0329
Schistosoma mansoni synaptojanin 0.0008 0.0013 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0166 0.0988
Schistosoma mansoni nuclear hormone receptor 0.002 0.0085 0.0138
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0013 0.0582
Onchocerca volvulus Putative neutral sphingomyelinase 0.0008 0.0013 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0085 0.0213
Brugia malayi AMP-binding enzyme family protein 0.0008 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0055 0.031 0.0777
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.0026 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.03 0.0752
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0166 0.2181
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Schistosoma mansoni bromodomain containing protein 0.0006 0 0.0001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0557 0.1397
Onchocerca volvulus 0.0008 0.001 0.0062
Schistosoma mansoni FFA transport protein 0.0615 0.3842 0.6227
Schistosoma mansoni tyrosine kinase 0.0007 0.0006 0.0009
Brugia malayi Bromodomain containing protein 0.0086 0.0503 0.1261
Treponema pallidum hypothetical protein 0.0008 0.0013 0.0039
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0019 0.003
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.001 0.0459
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0112 0.0182
Echinococcus granulosus geminin 0.0517 0.3224 0.8391
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0007 0.0006 0.0015
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0085 0.0085
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0158 0.0391
Schistosoma mansoni hypothetical protein 0.0046 0.0253 0.041
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0112 0.0182
Brugia malayi nuclear hormone receptor 0.0009 0.0019 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0085 0.0213
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0081 0.0081
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0031 0.0158 0.0371
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0008 0.0013 0.0007
Onchocerca volvulus 0.0008 0.0013 0.0078
Brugia malayi orphan nuclear receptor NR2E1 0.0009 0.0019 0.0047
Giardia lamblia hypothetical protein 0.0008 0.0013 0.0129
Echinococcus granulosus synaptojanin 1 0.0008 0.0013 0.0034
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Trichomonas vaginalis set domain proteins, putative 0.0271 0.1673 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0007 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0046 0.0253 0.041
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.0026 0.0065
Brugia malayi ecdysone receptor 0.0009 0.0019 0.0047
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0238 0.1465 0.3672
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0009 0.0019 0.0049
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Echinococcus multilocularis traf and tnf receptor associated protein 0.0008 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0085 0.0507
Onchocerca volvulus 0.0031 0.0158 0.0945
Echinococcus granulosus nuclear receptor nhr 48 0.0009 0.0019 0.0049
Echinococcus multilocularis AMP dependent ligase 0.0008 0.001 0.001
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0008 0.0013 0.0039
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0058 0.0421
Loa Loa (eye worm) nuclear hormone receptor 0.0009 0.0019 0.0047
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0139 0.0349
Loa Loa (eye worm) phosphofructokinase 0.0121 0.0722 0.1809
Loa Loa (eye worm) hypothetical protein 0.0045 0.0246 0.0616
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0031 0.0158 0.1142
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0166 1
Onchocerca volvulus 0.0031 0.0158 0.0945
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0008 0.0013 0.0039
Brugia malayi nuclear receptor RXR 0.0009 0.0019 0.0047
Schistosoma mansoni nuclear receptor 0.0009 0.0019 0.003
Leishmania major 4-coumarate:coa ligase-like protein 0.0031 0.0158 0.0391
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0225 0.0225
Brugia malayi Niemann-Pick C1 protein precursor 0.0106 0.0626 0.1569
Echinococcus multilocularis expressed conserved protein 0.0099 0.0586 0.0586
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0008 0.001 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0085 0.0213
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.001 0.0075
Echinococcus multilocularis Niemann Pick C1 protein 0.0151 0.0912 0.0912
Brugia malayi SRC-1 0.0007 0.0006 0.0014
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0013 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0189 0.1126
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 0.0008 0.001 0.0027
Echinococcus granulosus c src tyrosine kinase 0.0007 0.0006 0.0015
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0329 0.0534
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0009 0.0019 0.0019
Echinococcus multilocularis nuclear receptor nhr 48 0.0009 0.0019 0.0019
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.2514 0.2514
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.0019 0.0049
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0246 0.0639
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0211 0.1293 0.1293
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0179 0.029
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Loa Loa (eye worm) oxidoreductase 0.0031 0.0158 0.0396
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.0722 0.1882
Brugia malayi CCR4 0.0008 0.0013 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0225 0.0563
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.0253 0.0634
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0013 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Trypanosoma brucei RNA editing exonuclease 2 0.0008 0.0013 0.0039
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0031 0.0158 0.0396
Loa Loa (eye worm) hypothetical protein 0.0031 0.0158 0.0396
Schistosoma mansoni hypothetical protein 0.0044 0.0235 0.0381
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0225 0.1341
Schistosoma mansoni survival motor neuron protein 0.0095 0.0557 0.0903
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0008 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0147 0.0886 0.2221
Echinococcus multilocularis acyl coenzyme A synthetase family 0.0008 0.001 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0348 0.0564
Schistosoma mansoni hypothetical protein 0.0044 0.0235 0.0381
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Brugia malayi tailless protein 0.0009 0.0019 0.0047
Schistosoma mansoni coup transcription factor 0.002 0.0085 0.0138
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0225 0.0566
Echinococcus multilocularis protein patched 0.0045 0.0246 0.0246
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0085 0.0221
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0031 0.0158 0.7037
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 0.0008 0.001 0.0017
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.001 0.0026
Echinococcus granulosus long chain fatty acid transport protein 4 0.0615 0.3842 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0031 0.0158 0.2076
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 0.0008 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0085 0.0213
Echinococcus granulosus Niemann Pick C1 protein 0.0106 0.0626 0.1629
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0394 0.0394
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0158 0.0391
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0333 0.0333
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0333 0.0867
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0722 0.4315
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0166 0.7372
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0615 0.3842 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0009 0.0019 0.0047
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0058 0.0058
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0031 0.0158 0.0371
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0112 0.5
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0031 0.0158 0.0371
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0189 0.0473
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0722 1
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0107 0.0256
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0008 0.0013 0.0039
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0112 0.1433
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0008 0.0013 0.0039
Brugia malayi phosphofructokinase 0.0121 0.0722 0.1809
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0085 0.0085
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0012 0.0032
Trichomonas vaginalis antibiotic synthetase, putative 0.0031 0.0158 0.0943
Echinococcus multilocularis c src tyrosine kinase 0.0007 0.0006 0.0006
Onchocerca volvulus 0.002 0.0085 0.0507
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0179 0.1293
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0009 0.0019 0.0111
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0189 0.832
Echinococcus multilocularis tyrosine protein kinase Abl 0.0092 0.0539 0.0539
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0013 0.0033
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0638 0.399 1
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0036 0.0184 0.0299
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0284 0.17
Brugia malayi hypothetical protein 0.001 0.0026 0.0065
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 0.0008 0.001 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0189 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0333 0.0811
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0013 0.0033
Mycobacterium ulcerans acetyl-CoA synthetase 0.0031 0.0158 0.0371
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0085 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.03 0.0487
Schistosoma mansoni nuclear receptor 0.0009 0.0019 0.003
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0112 0.0182
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0615 0.3842 0.3842
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0085 0.0213
Plasmodium vivax hypothetical protein, conserved 0.0008 0.001 0.0459
Brugia malayi hypothetical protein 0.0008 0.001 0.0026
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 0.0008 0.001 0.001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.03 0.03
Brugia malayi steroid hormone receptor 0.002 0.0085 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0085 0.0213
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0031 0.0158 0.0158
Brugia malayi conserved hypotetical protein 0.0009 0.0019 0.0047
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0007 0.0006 0.0015
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0058 0.0058
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0007
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0012 0.0012
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.0253 0.0634
Loa Loa (eye worm) hypothetical protein 0.008 0.0462 0.1159
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0008 0.0013 0.0582
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0085 0.0507
Echinococcus granulosus expressed conserved protein 0.0099 0.0586 0.1524
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0085 0.0213
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0013 0.0077
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0033
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0246 0.0246
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.03 0.0781
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0211 0.1293 0.3365
Schistosoma mansoni thyroid hormone receptor 0.002 0.0085 0.0138
Toxoplasma gondii propionate-CoA ligase 0.0031 0.0158 0.1142
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0225 0.1341
Entamoeba histolytica hypothetical protein 0.0036 0.0184 0.2444
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0031 0.0158 0.0391
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0225 0.3011
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0166 0.0988
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0607 0.3792 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0593 0.1486
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0284 0.0461
Loa Loa (eye worm) DR-78 0.0009 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0722 0.4315
Onchocerca volvulus 0.0009 0.0019 0.0111
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0085 0.0138
Trichomonas vaginalis antibiotic synthetase, putative 0.0031 0.0158 0.0943
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0166 0.1197
Brugia malayi nuclear hormone receptor family member odr-7 0.0009 0.0019 0.0047
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0008 0.0013 0.0039
Entamoeba histolytica hypothetical protein 0.0036 0.0184 0.2444
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0031 0.0158 0.0371
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0187 0.1115
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0167 0.0435
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0163 0.0403
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0158 0.0396
Echinococcus granulosus tyrosine protein kinase Fyn 0.0007 0.0006 0.0015
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0215 0.056
Brugia malayi Disco-interacting protein 2 homolog 0.0008 0.001 0.0026
Trichomonas vaginalis Phospholipase C precursor, putative 0.0008 0.0013 0.0077
Trypanosoma cruzi ISWI complex protein 0.0017 0.0068 0.0151
Schistosoma mansoni cpg binding protein 0.0032 0.0163 0.0264
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0187 0.1115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0847 0.2204
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0031 0.0158 0.0391
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0058 0.2594
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 0.0008 0.001 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0085 0.0213
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0036 0.009
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0008 0.0013 0.0582
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0085 0.0221
Onchocerca volvulus 0.0035 0.0179 0.107
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0112 0.067
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0039
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0013 0.0033
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0058 0.0421
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0033
Brugia malayi nuclear hormone receptor family member nhr-6 0.0009 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0033
Echinococcus multilocularis zinc finger protein 0.0024 0.0109 0.0109
Entamoeba histolytica acyl-CoA synthetase, putative 0.0031 0.0158 0.2076
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Echinococcus granulosus acyl coenzyme A synthetase family 0.0008 0.001 0.0027
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0058 0.0125
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0008 0.0013 0.0034
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.005 0.0273 0.0684
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0013 0.0077
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0008 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0158 0.0396
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0085 0.0085
Brugia malayi Latrophilin receptor protein 2 0.0046 0.0253 0.0634
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0031 0.0158 0.0391
Loa Loa (eye worm) nuclear receptor NHR-67 0.0009 0.0019 0.0047
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0333 0.2407
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0847 0.2204
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0065
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.0019 0.0049
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0189 0.0189
Echinococcus multilocularis protein dispatched 1 0.0052 0.0286 0.0286
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0085 0.0213
Echinococcus multilocularis neutral sphingomyelinase 0.0008 0.0013 0.0013
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0008 0.0013 0.0077
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0158 0.0391
Leishmania major 4-coumarate:coa ligase-like protein 0.0031 0.0158 0.0391
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0189 0.0465
Loa Loa (eye worm) hypothetical protein 0.0043 0.0232 0.0583
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0085 0.0213
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0031 0.0158 0.0371
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0026 0.0065
Echinococcus granulosus neutral sphingomyelinase 0.0008 0.0013 0.0034
Echinococcus granulosus tyrosine protein kinase Fyn 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.013 0.0211
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0081 0.0131
Onchocerca volvulus 0.0008 0.0013 0.0078
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0158 0.0391
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Schistosoma mansoni hypothetical protein 0.0404 0.2514 0.4073
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0058 0.0058
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.001 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0008 0.001 0.006
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0008 0.0013 0.0007
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0085 0.0221
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0166 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.0187 0.0303
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0058 0.0127
Brugia malayi CHE-14 protein 0.0045 0.0246 0.0616
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0213
Toxoplasma gondii exonuclease III APE 0.0042 0.0225 0.1623
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0058 0.0095
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0031 0.0158 0.0371
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0189 0.2505
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0007 0.0006 0.0006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0215 0.0215
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0722 0.1809
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0284 0.074
Trichomonas vaginalis chaperonin, putative 0.0024 0.0112 0.067
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0722 0.1857
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0158 0.0391
Schistosoma mansoni AMP dependent ligase 0.0008 0.001 0.0017
Plasmodium falciparum DNase I-like protein, putative 0.0008 0.0013 0.0582
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0184 0.0299
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0008 0.001 0.006
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0008 0.001 0.006
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0284 0.0713
Leishmania major endonuclease/exonuclease protein-like protein 0.0008 0.0013 0.0007
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0007 0.0006 0.0006
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0284 0.0284
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0039
Brugia malayi Tyrosine-protein kinase abl-1 0.0137 0.0822 0.206
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0046 0.0253 0.0634
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0085 0.0138
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0112 0.0282
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0085 0.0213
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0026 0.0042
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0031 0.0158 0.0412
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0026
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0147 0.0886 0.2221
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 0.0008 0.001 0.0027
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0329 0.0826
Schistosoma mansoni nocturnin 0.0008 0.0013 0.0021
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0112 0.0282
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0008 0.0013 0.0007
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0225 0.0538
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Brugia malayi hypothetical protein 0.001 0.0026 0.0065
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.0112 0.4759
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0008 0.0013 0.0077
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0031 0.0158 0.0371
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0158 0.0385
Loa Loa (eye worm) hypothetical protein 0.0051 0.0284 0.0713
Brugia malayi mbt repeat family protein 0.0051 0.0284 0.0713
Schistosoma mansoni zinc finger protein 0.0009 0.0019 0.003
Schistosoma mansoni zinc finger protein 0.0017 0.0068 0.0111
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.0253 0.0658
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.0722 0.1879
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0246 0.0639
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0039
Schistosoma mansoni hypothetical protein 0.0044 0.0235 0.0381
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0225 0.1383 0.1383
Schistosoma mansoni ap endonuclease 0.0042 0.0225 0.0364
Leishmania major fatty acid transporter protein-like protein 0.0607 0.3792 1
Brugia malayi nuclear receptor NHR-67 0.0009 0.0019 0.0047
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0166 0.7372
Echinococcus granulosus tyrosine protein kinase Lyn 0.0007 0.0006 0.0015
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0008 0.001 0.0017
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0065
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0013 0.0033
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.001 0.0075
Plasmodium vivax long-chain-fatty-acid--CoA ligase, putative 0.0008 0.001 0.0459
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0058 0.0146
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0007 0.0006 0.0009
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0013 0.0007
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0008 0.0013 0.0007
Echinococcus granulosus traf and tnf receptor associated protein 0.0008 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0031 0.0158 0.1142
Schistosoma mansoni thyroid hormone receptor 0.002 0.0085 0.0138
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0722 0.117
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0225 0.1382 0.1382
Schistosoma mansoni hypothetical protein 0.0046 0.0253 0.041
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0329 0.0329
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0111
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Mycobacterium ulcerans hypothetical protein 0.0031 0.0158 0.0371
Trichomonas vaginalis AMP dependent ligase, putative 0.0008 0.001 0.006
Schistosoma mansoni tyrosine kinase 0.0007 0.0006 0.0009
Plasmodium vivax ATP-dependent acyl-CoA synthetase, putative 0.0008 0.001 0.0459
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Echinococcus multilocularis deoxyribonuclease 1 2 0.0008 0.0013 0.0013
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0008 0.001 0.0017
Brugia malayi mbt repeat family protein 0.0051 0.0284 0.0713
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.0253 0.0253
Echinococcus granulosus tyrosine protein kinase Fyn 0.0007 0.0006 0.0015
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0013 0.0582
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0013 0.0039
Echinococcus granulosus long chain fatty acid coenzyme A ligase 4 0.0008 0.001 0.0027
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0007 0.0006 0.0006
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.013 0.013
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0158 0.0396
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0187 0.0486
Brugia malayi 6-phosphofructokinase 0.0121 0.0722 0.1809
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.0636 0.1031
Schistosoma mansoni tyrosine kinase 0.0007 0.0006 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0847 0.2122
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0166 0.7372
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0085 0.0213
Entamoeba histolytica hypothetical protein 0.0036 0.0184 0.2444
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0333 0.0853
Echinococcus multilocularis Niemann Pick C1 protein 0.0106 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0047
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0329 0.0857
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0394 0.1026
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0166 0.7246
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0031 0.0158 0.0391
Brugia malayi PHD-finger family protein 0.003 0.0147 0.0368
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0008 0.0013 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0722 0.4315
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0026 0.0065
Echinococcus multilocularis synaptojanin 1 0.0008 0.0013 0.0013
Entamoeba histolytica acyl-coA synthetase, putative 0.0031 0.0158 0.2076
Brugia malayi 6-phosphofructokinase 0.0121 0.0722 0.1809
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0189 0.0306
Schistosoma mansoni hypothetical protein 0.0517 0.3224 0.5225
Schistosoma mansoni hypothetical protein 0.0321 0.1987 0.322
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0333 0.0811
Onchocerca volvulus 0.0051 0.0284 0.17
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0225 0.3011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0012 0.002
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0722 1
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0008 0.0013 0.0077
Schistosoma mansoni microsomal glutathione s-transferase 0.0225 0.1383 0.2241
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0085 0.0085
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0013 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0019 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0058 0.0058
Schistosoma mansoni acetyl-CoA synthetase 0.0031 0.0158 0.0256
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0166 0.0988
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 0.0008 0.001 0.001
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0112 0.027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0019 0.0049
Schistosoma mansoni inositol monophosphatase 0.0036 0.0187 0.0303
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0158 0.2076
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0007 0.0006 0.0006
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0085 0.0221
Loa Loa (eye worm) hypothetical protein 0.0464 0.289 0.7243
Schistosoma mansoni bromodomain containing protein 0.0073 0.042 0.068
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0013 0.0007
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0189 0.0491
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0031 0.0158 0.0371
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0333 0.054
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0013 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0158 0.0371
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0085 0.0213
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0166 0.7372
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0112 0.0812
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.0253 0.0253
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0333 0.0811
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0031 0.0158 0.0371
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0058 0.0146
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0847 0.2122
Brugia malayi hypothetical protein 0.0009 0.0019 0.0047
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.001 0.0459
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0333 0.054

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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