Detailed information for compound 800611

Basic information

Technical information
  • TDR Targets ID: 800611
  • Name: 6-methyl-N-(4-nitrophenyl)-2-phenyl-5-prop-2- enylpyrimidin-4-amine
  • MW: 346.383 | Formula: C20H18N4O2
  • H donors: 1 H acceptors: 4 LogP: 5.04 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCc1c(Nc2ccc(cc2)[N+](=O)[O-])nc(nc1C)c1ccccc1
  • InChi: 1S/C20H18N4O2/c1-3-7-18-14(2)21-19(15-8-5-4-6-9-15)23-20(18)22-16-10-12-17(13-11-16)24(25)26/h3-6,8-13H,1,7H2,2H3,(H,21,22,23)
  • InChiKey: WMGOTJBORZLLSI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-allyl-6-methyl-N-(4-nitrophenyl)-2-phenyl-pyrimidin-4-amine
  • (5-allyl-6-methyl-2-phenyl-pyrimidin-4-yl)-(4-nitrophenyl)amine
  • 6-methyl-N-(4-nitrophenyl)-2-phenyl-5-prop-2-enyl-pyrimidin-4-amine
  • ZINC03878905
  • STOCK1S-61052
  • 5-Allyl-4-methyl-6-(4-nitroanilino)-2-phenylpyrimidine
  • 5-Allyl-6-methyl-N-(4-nitrophenyl)-2-phenyl-4-pyrimidinamine
  • CBDivE_011042
  • Oprea1_808905

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0031 0.0409
Loa Loa (eye worm) hypothetical protein 0.0046 0.0248 0.0704
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0129 0.0125
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0072 0.0068
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0439 0.6586
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0086 0.0532 0.1509
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0124 0.2275
Schistosoma mansoni hypothetical protein 0.0015 0.0027 0.0023
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0439 0.6586
Mycobacterium ulcerans hypothetical protein 0.0073 0.0439 0.6586
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0064 0.0374 0.8526
Leishmania major GTP-binding protein, putative 0.0022 0.0075 0.1511
Echinococcus granulosus snurportin 1 0.0315 0.2164 0.2161
Onchocerca volvulus 0.0152 0.1003 0.2693
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0225 0.4178
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0401 0.0398
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0075 0.1067
Loa Loa (eye worm) RecQ helicase 0.0093 0.0582 0.1651
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0086 0.0532 0.0529
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0102 0.1553
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0072 0.1081
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.005 0.0274 0.5769
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0072 0.0456
Brugia malayi Bromodomain containing protein 0.0031 0.0141 0.0399
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0182 0.0178
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0075 0.1396
Entamoeba histolytica hypothetical protein 0.0037 0.0182 0.2813
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0086 0.0532 0.0529
Brugia malayi polk-prov protein 0.007 0.0419 0.1189
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0129 0.2368
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0666 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0086 0.0532 0.0529
Giardia lamblia Sgs1 DNA helicase, putative 0.0038 0.0193 0.4726
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0072 0.1462
Echinococcus granulosus flap endonuclease 1 0.0026 0.0102 0.0098
Echinococcus multilocularis sodium and chloride dependent glycine 0.0086 0.0532 0.0529
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0072 0.1032
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0075 0.1396
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0072 0.1032
Leishmania major DNA polymerase eta, putative 0.0077 0.0472 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0225 0.3332
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0228 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0121 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0439 0.1245
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0172 0.0168
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0072 0.0068
Trichomonas vaginalis DNA helicase recq, putative 0.0093 0.0582 0.3685
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0072 0.1081
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.009 0.057
Onchocerca volvulus 0.0086 0.0532 0.1331
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0228 0.0224
Leishmania major DNA damage repair protein, putative 0.0016 0.0031 0.058
Brugia malayi Bloom's syndrome protein homolog 0.0093 0.0582 0.1651
Schistosoma mansoni hypothetical protein 0.0042 0.0217 0.0213
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0439 0.6586
Loa Loa (eye worm) hypothetical protein 0.0282 0.1934 0.5482
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0422 0.6592
Trypanosoma cruzi ISWI complex protein 0.0015 0.0027 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0072 0.0205
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0167 0.0163
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0031 0.0409
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Echinococcus multilocularis dna polymerase eta 0.0077 0.0472 0.0468
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Brugia malayi hypothetical protein 0.0086 0.0532 0.1509
Plasmodium falciparum phd finger protein, putative 0.0029 0.0124 0.2328
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0439 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0439 0.6586
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0401 0.0398
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0193 0.3584
Brugia malayi Bromodomain containing protein 0.0074 0.0445 0.1262
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0287 0.6526
Echinococcus granulosus jumonji domain containing protein 0.004 0.0204 0.02
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0205
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Loa Loa (eye worm) hypothetical protein 0.0506 0.3527 1
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.1003 0.0999
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0086 0.0532 0.1509
Loa Loa (eye worm) hypothetical protein 0.0069 0.0415 0.1177
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0451 0.0448
Onchocerca volvulus Alhambra homolog 0.0029 0.0124 0.015
Loa Loa (eye worm) hypothetical protein 0.0101 0.0638 0.1808
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0124 0.012
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0072 0.0205
Loa Loa (eye worm) serotonin transporter b 0.0506 0.3527 1
Trypanosoma brucei DNA polymerase IV, putative 0.0091 0.057 0.8545
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0439 0.1245
Leishmania major hypothetical protein, conserved 0.0015 0.0027 0.0495
Schistosoma mansoni blooms syndrome DNA helicase 0.0073 0.0443 0.0439
Entamoeba histolytica hypothetical protein 0.0037 0.0182 0.2813
Schistosoma mansoni flap endonuclease-1 0.0023 0.0085 0.0081
Echinococcus multilocularis bloom syndrome protein 0.0093 0.0582 0.0579
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0075 0.1269
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0666 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0439 0.1245
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0422 0.1195
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0072 0.1081
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0031 0.0409
Trichomonas vaginalis ran, putative 0.0022 0.0075 0.047
Giardia lamblia PHD finger protein 15 0.0029 0.0124 0.2712
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0039 0.0035
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0228 0.0646
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1378 0.3906
Loa Loa (eye worm) hypothetical protein 0.0073 0.0439 0.1245
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0072 0.1081
Echinococcus multilocularis protein patched 0.0043 0.0228 0.0224
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.005 0.0274 0.4073
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0401 0.0398
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Plasmodium falciparum importin beta, putative 0.0029 0.013 0.244
Onchocerca volvulus 0.0233 0.1579 0.4362
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0075 0.1067
Loa Loa (eye worm) RNA binding protein 0.0068 0.0401 0.1138
Entamoeba histolytica recQ family helicase, putative 0.005 0.0274 0.4257
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0054 0.0789
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0248 0.0245
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0182 0.0178
Trichomonas vaginalis DNA polymerase eta, putative 0.0105 0.0666 0.4218
Loa Loa (eye worm) hypothetical protein 0.0049 0.027 0.0766
Loa Loa (eye worm) hypothetical protein 0.0054 0.0308 0.0873
Entamoeba histolytica hypothetical protein 0.0024 0.009 0.1364
Brugia malayi Pre-SET motif family protein 0.0029 0.0129 0.0366
Schistosoma mansoni terminal deoxycytidyl transferase 0.005 0.0278 0.0274
Schistosoma mansoni sodium/chloride dependent transporter 0.0086 0.0532 0.0529
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0638 1
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0072 0.1081
Schistosoma mansoni zinc finger protein 0.0015 0.0027 0.0023
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0086 0.0532 0.1509
Mycobacterium tuberculosis Conserved hypothetical protein 0.005 0.0278 0.6329
Loa Loa (eye worm) hypothetical protein 0.0506 0.3527 1
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0278 0.0788
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0308 0.578
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0102 0.1862
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0072 0.0068
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0072 0.1079
Echinococcus granulosus sodium and chloride dependent glycine 0.0086 0.0532 0.0529
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0086 0.0532 1
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.013 0.2388
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0506 0.3527 0.3525
Brugia malayi Flap endonuclease-1 0.0026 0.0102 0.029
Plasmodium falciparum flap endonuclease 1 0.0026 0.0102 0.1918
Loa Loa (eye worm) hypothetical protein 0.0042 0.0219 0.062
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0072 0.1641
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0308 0.4616
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0193 0.0548
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0589 0.0585
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0401 0.0398
Loa Loa (eye worm) hypothetical protein 0.0038 0.0189 0.0535
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.005 0.0274 0.4073
Echinococcus multilocularis protein dispatched 1 0.0049 0.0271 0.0268
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0039 0.0035
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Onchocerca volvulus 0.0506 0.3527 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0072 0.1032
Schistosoma mansoni microtubule-associated protein tau 0.1414 1 1
Loa Loa (eye worm) 3'-5' exonuclease 0.0012 0.0004 0.0011
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.013 0.1905
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0205
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0038 0.0193 0.0189
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0342 0.0968
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0287 0.6526
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0044 0.0124
Plasmodium falciparum amino acid transporter, putative 0.0086 0.0532 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0078 0.0074
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0072 0.1641
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0548
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0439 0.6866
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0072 0.1294
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0204 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0059 0.0835
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Trypanosoma brucei DNA polymerase eta, putative 0.0077 0.0472 0.706
Schistosoma mansoni DNA polymerase eta 0.0077 0.0472 0.0468
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0422 0.8932
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0263 0.3914
Echinococcus multilocularis dna polymerase kappa 0.0105 0.0666 0.0663
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0124 0.012
Toxoplasma gondii hypothetical protein 0.0086 0.0532 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.005 0.0278 0.4325
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Schistosoma mansoni patched 1 0.0043 0.0228 0.0224
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0072 0.1572
Loa Loa (eye worm) hypothetical protein 0.0029 0.0124 0.0352
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0439 0.9303
Echinococcus granulosus sodium and chloride dependent glycine 0.0086 0.0532 0.0529
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0129 0.0125
Echinococcus multilocularis importin subunit beta 1 0.0029 0.013 0.0126
Schistosoma mansoni bromodomain containing protein 0.0062 0.0363 0.0359
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0439 0.6586
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0666 1
Echinococcus granulosus dna polymerase eta 0.0077 0.0472 0.0468
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0638 0.0634
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0062 0.0362 0.6786
Schistosoma mansoni sodium/chloride dependent transporter 0.0506 0.3527 0.3525
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0248 0.0245
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0072 0.1032
Loa Loa (eye worm) hypothetical protein 0.002 0.0059 0.0168
Brugia malayi jmjC domain containing protein 0.0037 0.018 0.0512
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0102 0.0646
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0072 0.1641
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0666 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0086 0.0532 0.0529
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Schistosoma mansoni ran 0.0022 0.0075 0.0071
Schistosoma mansoni sodium-dependent amino acid transporter 0.0086 0.0532 0.0529
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Trichomonas vaginalis importin beta-1, putative 0.0024 0.009 0.057
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0086 0.0532 0.1509
Loa Loa (eye worm) hypothetical protein 0.0152 0.1003 0.2843
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0072 0.1641
Schistosoma mansoni hypothetical protein 0.0042 0.0217 0.0213
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.079 0.224
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Mycobacterium ulcerans hypothetical protein 0.0012 0.0004 0.0054
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0019 0.0054 0.1008
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0439 0.1245
Brugia malayi 3'-5' exonuclease family protein 0.0012 0.0004 0.0011
Brugia malayi TAR-binding protein 0.0068 0.0401 0.1138
Brugia malayi Pre-SET motif family protein 0.0204 0.1378 0.3906
Echinococcus multilocularis peregrin 0.0031 0.0141 0.0137
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0338 0.0334
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0072 0.0205
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.005 0.0278 0.0274
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0039 0.0035
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0031 0.0409
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0072 0.0205
Schistosoma mansoni hypothetical protein 0.0029 0.0124 0.012
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0038 0.0193 0.0189
Echinococcus multilocularis tumor protein p63 0.1038 0.7319 0.7318
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0072 0.1641
Brugia malayi MH2 domain containing protein 0.0122 0.079 0.224
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.0127 0.2337
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0072 0.1081
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0038 0.0193 0.0189
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0072 0.1462
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0075 0.1067
Loa Loa (eye worm) hypothetical protein 0.0073 0.0439 0.1245
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Brugia malayi PHD-finger family protein 0.0029 0.0124 0.0352
Onchocerca volvulus 0.0086 0.0532 0.1331
Trypanosoma brucei unspecified product 0.0091 0.057 0.8545
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0086 0.0532 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.005 0.0278 0.0274
Treponema pallidum sodium- and chloride- dependent transporter 0.0506 0.3527 1
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1579 1
Plasmodium vivax SET domain protein, putative 0.0029 0.0129 0.2419
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0072 0.1641
Onchocerca volvulus 0.0086 0.0532 0.1331
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0064 0.0183
Mycobacterium tuberculosis Conserved hypothetical alanine rich protein 0.0012 0.0004 0.0082
Brugia malayi Importin beta-1 subunit 0.0029 0.013 0.0369
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0439 0.6866
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.009 0.1305
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0038 0.0193 0.0548
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0072 0.1572
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0439 0.6586
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0072 0.1641
Loa Loa (eye worm) hypothetical protein 0.0053 0.0297 0.0843
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0102 0.2076
Loa Loa (eye worm) norepinephrine transporter 0.0506 0.3527 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0124 0.012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0129 0.0125
Echinococcus multilocularis serotonin transporter 0.0506 0.3527 0.3525
Schistosoma mansoni hypothetical protein 0.0037 0.0182 0.0178
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0124 0.0352
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.009 0.057
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0829 0.5832 0.583
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0102 0.0098
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0422 0.6306
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0072 0.1081
Plasmodium vivax importin-beta 2, putative 0.0029 0.013 0.244
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0401 0.0398
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0072 0.1462
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0064 0.0374 0.792
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0102 0.029
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0072 0.1353
Echinococcus granulosus dna polymerase kappa 0.0105 0.0666 0.0663
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.018 0.0177
Trypanosoma brucei unspecified product 0.0035 0.0167 0.2459
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0401 0.1138
Echinococcus granulosus importin subunit beta 1 0.0029 0.013 0.0126
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0666 1
Leishmania major DNA polymerase kappa, putative 0.0016 0.0031 0.058
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.0472 0.1337
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0082 0.0502 0.9427
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.005 0.0278 0.0274
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0072 0.1641
Brugia malayi Bromodomain containing protein 0.0038 0.0188 0.0533
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0086 0.0532 0.0529
Onchocerca volvulus 0.0073 0.0439 0.1061
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0072 0.1032
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0059 0.0055
Trichomonas vaginalis DNA helicase recq1, putative 0.0093 0.0582 0.3685
Trypanosoma cruzi DNA polymerase eta, putative 0.0077 0.0472 0.706
Echinococcus multilocularis microtubule associated protein 2 0.1414 1 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0059 0.0835
Loa Loa (eye worm) hypothetical protein 0.007 0.0419 0.1189
Echinococcus multilocularis snurportin 1 0.0315 0.2164 0.2161
Brugia malayi PHD-finger family protein 0.0024 0.0094 0.0268
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0075 0.0211
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0072 0.1641
Schistosoma mansoni ran 0.0022 0.0075 0.0071
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0228 0.0224
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0422 0.6306
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0075 0.0211
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0439 0.6586
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0031 0.0409
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0086 0.0532 1
Trypanosoma brucei unspecified product 0.0035 0.0167 0.2459
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.021 0.0206
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.018 0.0512
Loa Loa (eye worm) hypothetical protein 0.0054 0.0308 0.0873
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0439 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0102 0.1485
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0072 0.1294
Leishmania major importin beta-1 subunit, putative 0.0024 0.009 0.1848
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0646
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0369
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0401 0.0398
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0338 0.0334
Echinococcus multilocularis sodium and chloride dependent glycine 0.0086 0.0532 0.0529
Trypanosoma brucei ISWI complex protein 0.0015 0.0027 0.0349
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0102 0.1485
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.2164 0.6135
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0439 0.9303
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0072 0.1641
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0248 0.0245
Mycobacterium ulcerans hypothetical protein 0.0016 0.0031 0.0461
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0075 0.0071
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Schistosoma mansoni importin beta-1 0.0029 0.013 0.0126
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Entamoeba histolytica hypothetical protein 0.0037 0.0182 0.2813
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0287 0.6526
Schistosoma mansoni hypothetical protein 0.0042 0.0217 0.0213
Schistosoma mansoni hypothetical protein 0.0315 0.2164 0.2161
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0072 0.1572
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0172 0.0168
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0031 0.0577
Loa Loa (eye worm) solute carrier family 6 member 4 0.0506 0.3527 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0666 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0439 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0038 0.0193 0.0189
Plasmodium vivax hypothetical protein, conserved 0.0086 0.0532 1
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0401 0.1138
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0308 0.578
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0422 0.0418
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0072 0.1353
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0946 0.0942
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0072 0.1081
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0086 0.0532 0.1509
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0072 0.0456
Brugia malayi hypothetical protein 0.0037 0.0182 0.0516
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0102 0.2104
Toxoplasma gondii hypothetical protein 0.0086 0.0532 1
Echinococcus granulosus serotonin transporter 0.0506 0.3527 0.3525
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0666 1
Plasmodium vivax amine transporter, putative 0.0086 0.0532 1
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0124 0.2328
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0666 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0308 0.0873
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0182 0.0178
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0638 0.1808
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.005 0.0278 0.0788
Onchocerca volvulus 0.0029 0.0129 0.0164
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0422 0.6306
Trichomonas vaginalis DNA helicase recq, putative 0.005 0.0274 0.1731
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0031 0.0513
Loa Loa (eye worm) oxidoreductase 0.0021 0.0072 0.0205
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0086 0.0532 0.0529
Schistosoma mansoni hypothetical protein 0.0042 0.0217 0.0213
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0063 0.0368 0.6907
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.013 0.1905
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.018 0.0177
Loa Loa (eye worm) hypothetical protein 0.0077 0.0472 0.1337
Schistosoma mansoni DNA helicase recq1 0.0038 0.0193 0.0189
Leishmania major DNA polymerase eta, putative 0.0043 0.0225 0.472
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0102 0.1918
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0086 0.0532 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0086 0.0532 0.0529
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0439 0.9303
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0086 0.0532 0.0529
Loa Loa (eye worm) hypothetical protein 0.0506 0.3527 1
Entamoeba histolytica Ran family GTPase 0.0022 0.0075 0.1115
Schistosoma mansoni hypothetical protein 0.002 0.0064 0.0061
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0031 0.0409
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0422 0.1195
Brugia malayi CHE-14 protein 0.0043 0.0228 0.0646
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0051 0.1158
Loa Loa (eye worm) hypothetical protein 0.0086 0.0532 0.1509
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0059 0.1047
Echinococcus multilocularis expressed conserved protein 0.0095 0.0594 0.059
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0263 0.3914
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0039 0.0035
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0649 0.0645
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0078 0.0074
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0072 0.1081
Echinococcus granulosus peregrin 0.0031 0.0141 0.0137
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0193 0.3584
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0072 0.1294
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0422 0.0418
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0031 0.0409
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0031 0.0409
Echinococcus granulosus tar DNA binding protein 0.0068 0.0401 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0228 0.1441
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0072 0.0205
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0072 0.0205
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0014 0.0016 0.0363
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0589 0.0585
Schistosoma mansoni zinc finger protein 0.0019 0.0057 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0374 0.5592
Plasmodium falciparum transporter, putative 0.0086 0.0532 1
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0946 0.0942
Brugia malayi RNA, U transporter 1 0.0084 0.0518 0.1468
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0419 0.6272
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0072 0.1081
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0078 0.0074
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0086 0.0532 0.1509
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0193 0.0548
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0038 0.0193 0.3628
Entamoeba histolytica hypothetical protein 0.0037 0.0182 0.2813
Plasmodium vivax exosome complex exonuclease RRP6, putative 0.0012 0.0004 0.0068
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0008 0.0022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0439 0.6866
Echinococcus granulosus transcription factor Dp 1 0.0041 0.021 0.0206
Echinococcus granulosus zinc finger protein 0.0019 0.0057 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0263 0.3914
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0401 0.1138
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0439 1
Echinococcus granulosus tumor protein p63 0.1038 0.7319 0.7318
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0072 0.1641
Leishmania major DNA polymerase kappa, putative 0.0064 0.0374 0.792
Entamoeba histolytica recQ family DNA helicase 0.002 0.0059 0.0873
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0031 0.0409
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0308 0.7009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0248 0.0245
Brugia malayi jmjC domain containing protein 0.0094 0.0589 0.1669
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0072 0.0205
Schistosoma mansoni DNA helicase recq5 0.0038 0.0193 0.0189
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0031 0.0577
Echinococcus multilocularis zinc finger protein 0.0019 0.0057 0.0053
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0075 0.1338
Loa Loa (eye worm) hypothetical protein 0.0054 0.0308 0.0873
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0422 0.0418
Giardia lamblia DINP protein human, muc B family 0.0064 0.0374 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0075 0.0071
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0638 0.0634
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0124 0.2275
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0287 0.6526
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0666 1
Brugia malayi RNA binding protein 0.0068 0.0401 0.1138
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0506 0.3527 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.079 0.224
Echinococcus granulosus expressed conserved protein 0.0095 0.0594 0.059
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0105 0.0666 0.4218
Loa Loa (eye worm) hypothetical protein 0.004 0.0205 0.0582
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0072 0.0205
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0072 0.1032
Echinococcus granulosus bloom syndrome protein 0.0093 0.0582 0.0579
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.018 0.0177
Schistosoma mansoni sodium/chloride dependent transporter 0.0086 0.0532 0.0529
Trypanosoma cruzi ISWI complex protein 0.0015 0.0027 0.0349
Loa Loa (eye worm) hypothetical protein 0.0054 0.0308 0.0873
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0419 0.6272

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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