Detailed information for compound 873994

Basic information

Technical information
  • TDR Targets ID: 873994
  • Name: 5-chloro-N-(2-dimethylaminoethyl)-N-(6-ethyl- 1,3-benzothiazol-2-yl)thiophene-2-carboxamide
  • MW: 393.954 | Formula: C18H20ClN3OS2
  • H donors: 0 H acceptors: 2 LogP: 5.54 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc2c(c1)sc(n2)N(C(=O)c1ccc(s1)Cl)CCN(C)C
  • InChi: 1S/C18H20ClN3OS2/c1-4-12-5-6-13-15(11-12)25-18(20-13)22(10-9-21(2)3)17(23)14-7-8-16(19)24-14/h5-8,11H,4,9-10H2,1-3H3
  • InChiKey: RHJQCEJZUBMVIZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-chloro-N-(2-dimethylaminoethyl)-N-(6-ethyl-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0697 0.0696
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0394 0.0939
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0016 0.0092
Brugia malayi PHD-finger family protein 0.0034 0.0088 0.0611
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0045 0.0141 0.0337
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0017 0.0017
Leishmania major eukaryotic translation initiation factor-like protein 0.0035 0.0093 0.067
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0679 0.1096
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0044 0.0134 0.0924
Onchocerca volvulus 0.0058 0.0198 0.2682
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0198 0.1368
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0078 0.0078
Treponema pallidum NADH oxidase 0.0022 0.0033 0.0078
Leishmania major metacaspase, putative 0.0044 0.0134 0.0969
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0224 0.0224
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0022 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0134 0.0273
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0022 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0118
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0187 0.1291
Mycobacterium ulcerans hypothetical protein 0.0162 0.0679 0.1059
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0012 0.0011
Brugia malayi nuclear hormone receptor 0.0032 0.0078 0.0536
Brugia malayi Temporarily assigned gene name protein 44 0.0028 0.0059 0.0408
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0027 0.0027
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0078 0.0186
Brugia malayi Doublecortin family protein 0.002 0.0022 0.0147
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0101 0.0101
Leishmania major succinate dehydrogenase flavoprotein, putative 0.0021 0.0029 0.0188
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0078 0.0077
Brugia malayi translation initiation factor 4E 0.0035 0.0093 0.0645
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0106 0.0422 0.0673
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0209 0.0322
Leishmania major hypothetical protein, conserved 0.0027 0.0058 0.0409
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0124
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0003 0.0067
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0134 0.0969
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Onchocerca volvulus 0.0049 0.0155 0.2109
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0035 0.0093 0.0093
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0009 0.0008
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0045 0.0141 0.0141
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0035 0.0093 0.0093
Schistosoma mansoni jumonji domain containing protein 0.0058 0.02 0.02
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0022 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0047 0.0147 0.1018
Trypanosoma brucei metacaspase MCA3 0.0044 0.0134 0.0969
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0167 0.0351
Schistosoma mansoni caspase-7 (C14 family) 0.0116 0.0466 0.0466
Plasmodium falciparum flavoprotein subunit of succinate dehydrogenase 0.0021 0.0029 0.1391
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0066 0.3424
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0078 0.0077
Echinococcus granulosus hypothetical protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0119 0.0862
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0209 0.0311
Plasmodium vivax glutathione reductase, putative 0.0047 0.0149 0.7988
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0078 0.0536
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0017 0.0017
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0174 0.0736 0.5102
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0078 0.0078
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0029 0.0195
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0022 0.0033 0.0225
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0078 0.0077
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0016 0.033
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0021 0.0029 0.0382
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0194 0.1341
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0016 0.0092
Trypanosoma cruzi trypanothione reductase, putative 0.0022 0.0033 0.022
Giardia lamblia NADH oxidase lateral transfer candidate 0.0022 0.0033 0.0031
Echinococcus multilocularis caspase 0.0116 0.0466 0.0466
Giardia lamblia Fructose-bisphosphate aldolase 0.0924 0.4196 1
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0019
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0078 0.014
Schistosoma mansoni microtubule-associated protein tau 0.2182 1 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Trypanosoma cruzi metacaspase, putative 0.0044 0.0134 0.0969
Brugia malayi succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial 0.005 0.0161 0.1113
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0044 0.0934
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.135 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0184 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0007 0.003
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0074 0.0273 0.2003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0131 0.0949
Brugia malayi hypothetical protein 0.0174 0.0736 0.5102
Schistosoma mansoni coup transcription factor 0.0032 0.0078 0.0078
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0016 0.068
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0066 0.1398
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0134 0.0969
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0078 0.0077
Brugia malayi Bromodomain containing protein 0.0085 0.0324 0.2243
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0078 0.0556
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.01 0.0193
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0066 0.3424
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0155 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0078 0.0536
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0093 0.067
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.02 0.02
Toxoplasma gondii exonuclease III APE 0.0019 0.002 0.042
Brugia malayi hypothetical protein 0.0019 0.0018 0.0122
Brugia malayi hypothetical protein 0.002 0.0022 0.0147
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0022 0.1011
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1378 0.6289 1
Brugia malayi hypothetical protein 0.0029 0.0066 0.0452
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0187 0.0186
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0003 0.0003
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0003 0.0003
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0022 0.0033 0.0695
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0074 0.0273 0.1891
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Schistosoma mansoni hypothetical protein 0.0041 0.0123 0.0123
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0167 0.1152
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0101 0.0195
Echinococcus granulosus protein quaking 0.0028 0.0059 0.0059
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Trichomonas vaginalis mercuric reductase, putative 0.0022 0.0033 0.0031
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0151 0.3199
Loa Loa (eye worm) succinate-ubiquinone oxidoreductase 0.0021 0.0029 0.0195
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0045 0.0141 0.1026
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0631 0.0631
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0394 0.0393
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0101 0.0241
Trypanosoma cruzi NADH dehydrogenase, putative 0.0033 0.0082 0.0582
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Schistosoma mansoni hypothetical protein 0.002 0.0022 0.0022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0194 0.0287
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0134 0.2834
Onchocerca volvulus 0.0076 0.0284 0.386
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0394 0.0393
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0119 0.0168
Leishmania major eukaryotic translation initiation factor-like 0.0035 0.0093 0.067
Plasmodium vivax metacaspase 1, putative 0.0044 0.0134 0.7154
Trypanosoma cruzi metacaspase, putative 0.0044 0.0134 0.0969
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0045 0.0141 0.0291
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0167 0.0166
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.002 0.0134
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0124
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0209 0.0311
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.02 0.02
Brugia malayi tumor suppressor. 0.0327 0.1442 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.01 0.571
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.002 0.0912
Trichomonas vaginalis glutathione reductase, putative 0.0022 0.0033 0.0031
Onchocerca volvulus 0.0174 0.0736 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0194 0.1415
Echinococcus multilocularis transcription factor eb 0.0124 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0147
Echinococcus multilocularis protein dispatched 1 0.0049 0.0158 0.0158
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0066 0.0464
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0209 0.0209
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Brugia malayi CXXC zinc finger family protein 0.0058 0.0198 0.1368
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0924 0.4196 1
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0078 0.0077
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0134 0.0134
Brugia malayi polk-prov protein 0.0031 0.0074 0.0507
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0194 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0101 0.0728
Mycobacterium ulcerans succinate dehydrogenase iron-sulfur subunit 0.0027 0.0058 0.0071
Plasmodium vivax flavoprotein subunit of succinate dehydrogenase, putative 0.0021 0.0029 0.1391
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0003 0.0003
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0187 0.0186
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0078 0.105
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0078 0.0078
Brugia malayi Cell death protein 3 precursor 0.012 0.0486 0.3372
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0141 0.757
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0019
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0074 0.0273 0.2003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.01 0.0193
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0019
Onchocerca volvulus Cell death protein 3 homolog 0.012 0.0486 0.661
Echinococcus multilocularis microtubule associated protein 2 0.2182 1 1
Leishmania major DNA polymerase kappa, putative 0.0021 0.0028 0.0183
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0119 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Echinococcus granulosus caspase 0.0116 0.0466 0.0466
Schistosoma mansoni cpg binding protein 0.0058 0.0198 0.0198
Schistosoma mansoni CREB-binding protein 2 0.0106 0.0423 0.0423
Schistosoma mansoni protein kinase 0.0074 0.0273 0.0273
Echinococcus granulosus CREB binding protein 0.0068 0.0245 0.0245
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0093 0.0176
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0187 0.0186
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0055 0.0186 1
Echinococcus granulosus CREB binding protein 0.0106 0.0423 0.0422
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0016 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0078 0.0078
Echinococcus multilocularis CREB binding protein 0.0016 0.0007 0.0007
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0119 0.0119
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0603 0.4452
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0078 0.0077
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.005 0.0161 0.016
Echinococcus multilocularis neuropeptide s receptor 0.0471 0.2103 0.2103
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0209 0.0209
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0209 0.4432
Plasmodium falciparum glutathione reductase 0.0047 0.0149 0.7988
Schistosoma mansoni DNA helicase recq1 0.0029 0.0066 0.0066
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0252 0.0251
Mycobacterium tuberculosis Probable reductase 0.0096 0.0376 0.0598
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0078 0.0077
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0016 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0697 0.0696
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0195 0.0832 0.0832
Echinococcus granulosus Protein patched homolog 1 0.0043 0.013 0.0129
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0096 0.0376 0.0598
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0078 0.0536
Trypanosoma brucei metacaspase MCA2 0.0044 0.0134 0.0969
Loa Loa (eye worm) hypothetical protein 0.0047 0.0148 0.1021
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0022 0.0148
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0078 0.0077
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0074 0.0273 0.2003
Schistosoma mansoni caspase-7 (C14 family) 0.012 0.0486 0.0486
Loa Loa (eye worm) tumor suppressor 0.0327 0.1442 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0134 0.0273
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0022 0.0033 0.022
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0003 0.0019
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0141 0.018
Schistosoma mansoni alpha-glucosidase 0.0143 0.059 0.059
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0003 0.0003
Schistosoma mansoni alpha-glucosidase 0.0143 0.059 0.059
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0003 0.0019
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0167 0.1213
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0119 0.0238
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0101 0.0195
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0003 0.0003
Echinococcus multilocularis protein patched 0.0043 0.013 0.0129
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0093 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0078 0.0536
Plasmodium falciparum thioredoxin reductase 0.0047 0.0149 0.7988
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0096 0.0376 0.0598
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.002 0.0019
Treponema pallidum fructose-bisphosphate aldolase 0.0924 0.4196 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.01 0.0721
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0035 0.0093 0.1981
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0021 0.0029 0.0382
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0066 0.344
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0119 0.0862
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0055 0.0186 0.1285
Trypanosoma brucei trypanothione reductase 0.0047 0.0149 0.1082
Schistosoma mansoni hypothetical protein 0.0028 0.0059 0.0059
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0016 0.0015
Schistosoma mansoni lipoxygenase 0.002 0.0022 0.0022
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0033 0.0082 0.4299
Mycobacterium tuberculosis Probable succinate dehydrogenase (flavoprotein subunit) SdhA (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogena 0.0021 0.0029 0.0024
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0033 0.0082 0.173
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0016 0.068
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0209 0.1529
Echinococcus multilocularis cpg binding protein 0.0063 0.0222 0.0221
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0125 0.0251
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0066 0.0454
Schistosoma mansoni zinc finger protein 0.0029 0.0063 0.0063
Trypanosoma cruzi succinate dehydrogenase, putative 0.0032 0.0079 0.056
Echinococcus granulosus phd:f box containing protein 0.0016 0.0003 0.0003
Echinococcus multilocularis protein quaking 0.0028 0.0059 0.0059
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0056 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0078 0.0536
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0047 0.2385
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.01 0.0138
Plasmodium falciparum thioredoxin reductase 0.0022 0.0033 0.1624
Echinococcus granulosus CREB binding protein 0.0016 0.0007 0.0007
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0035 0.0093 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Loa Loa (eye worm) hypothetical protein 0.0141 0.0584 0.4046
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0022 0.0033 0.1432
Schistosoma mansoni hypothetical protein 0.0021 0.0028 0.0028
Brugia malayi hypothetical protein 0.0017 0.0009 0.0057
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0115 0.0228
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0408
Loa Loa (eye worm) hypothetical protein 0.0055 0.0187 0.1291
Trypanosoma cruzi ISWI complex protein 0.0016 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0158 0.109
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit, putative 0.0032 0.0079 0.056
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0022 0.1011
Brugia malayi ecdysteroid receptor 0.0032 0.0078 0.0536
Loa Loa (eye worm) RecQ helicase 0.0042 0.0125 0.0863
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0022 0.0033 0.003
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0016 0.0015
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.005 0.0161 0.0161
Brugia malayi CHE-14 protein 0.0043 0.013 0.0898
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0022 0.0033 0.022
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0014 0.0013
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0078 0.0536
Echinococcus granulosus caspase 3 0.0072 0.0264 0.0263
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.01 0.0239
Schistosoma mansoni inositol monophosphatase 0.0037 0.01 0.01
Trypanosoma brucei metacaspase 0.0044 0.0134 0.0969
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0603 0.4452
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0078 0.0536
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0101 0.0728
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0593 0.0593
Echinococcus granulosus succinate dehydrogenase (ubiquinone) iron sulfur 0.005 0.0161 0.016
Echinococcus granulosus transcription factor eb 0.0124 0.0506 0.0506
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0019
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0033 0.0922
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0167 0.353
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.01 0.01
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0697 0.0696
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0101 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0007 0.003
Trichomonas vaginalis STE family protein kinase 0.0074 0.0273 0.0606
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0007 0.003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0014 0.0013
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0012 0.0012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0472 1
Mycobacterium tuberculosis Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) 0.0021 0.0029 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0134 0.0273
Echinococcus granulosus expressed conserved protein 0.0094 0.0366 0.0365
Loa Loa (eye worm) hypothetical protein 0.0047 0.0149 0.1031
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0167 0.0166
Loa Loa (eye worm) glutathione reductase 0.0047 0.0149 0.103
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0003 0.0067
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0016 0.0105
Loa Loa (eye worm) hypothetical protein 0.0052 0.0172 0.1188
Brugia malayi jmjC domain containing protein 0.0063 0.0224 0.1554
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0012 0.0012
Echinococcus granulosus caspase 8 0.0044 0.0134 0.0133
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit 0.0027 0.0058 0.0409
Schistosoma mansoni caspase-3 (C14 family) 0.0116 0.0466 0.0466
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0078 0.0078
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0078 0.0077
Schistosoma mansoni hypothetical protein 0.0299 0.1311 0.1311
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0155 0.0155
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0697 0.483
Echinococcus granulosus succinate dehydrogenase ubiquinone 0.0021 0.0029 0.0028
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0055 0.0186 0.3935
Loa Loa (eye worm) hypothetical protein 0.0031 0.0074 0.0507
Schistosoma mansoni inositol monophosphatase 0.0037 0.01 0.01
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0167 0.1213
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0057
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0184 0.0183
Echinococcus granulosus cpg binding protein 0.0063 0.0222 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0078 0.0536
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0167 0.0351
Trypanosoma brucei Metacaspase-4 0.0044 0.0134 0.0969
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0224 0.0224
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0078 0.0078
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0033 0.0922
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.135 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0078 0.0536
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0078 0.0078
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0003 0.0019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0101 0.0241
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0039 0.0269
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0057
Plasmodium falciparum metacaspase-like protein 0.0044 0.0134 0.7154
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0151 0.3199
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0151 0.0314
Echinococcus granulosus CREB binding protein 0.0016 0.0007 0.0007
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0195 0.0832 0.0832
Echinococcus granulosus bloom syndrome protein 0.0042 0.0125 0.0124
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0014 0.0093
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0003 0.0003
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0155 0.0155
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0078 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0028 0.0183
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0078 0.0077
Brugia malayi glutathione reductase 0.0047 0.0149 0.103
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0167 0.1213
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0101 0.2147
Trypanosoma cruzi metacaspase, putative 0.0044 0.0134 0.0969
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0078 0.0077
Brugia malayi hypothetical protein 0.002 0.0022 0.0147
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0252 0.0251
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0134 0.0969
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0033 0.022
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0066 0.0454
Echinococcus granulosus caspase 2 0.012 0.0486 0.0486
Schistosoma mansoni hypothetical protein 0.0041 0.0123 0.0123
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0033 0.0082 0.173
Schistosoma mansoni hypothetical protein 0.0041 0.0123 0.0123
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0155 0.0155
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.01 0.01
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.135 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0083 0.0114
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0003 0.0003
Brugia malayi Bromodomain containing protein 0.0044 0.0136 0.0941
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0115 0.6129
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0028 0.0183
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0194 0.0193
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.002 0.0047
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0078 0.0078
Leishmania major succinate dehydrogenase, putative 0.0032 0.0079 0.056
Echinococcus multilocularis expressed protein 0.0055 0.0186 0.0185
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0028 0.0023
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0209 0.0209
Brugia malayi steroid hormone receptor 0.0032 0.0078 0.0536
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0053 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0167 0.1213
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0101 0.0195
Loa Loa (eye worm) MBCTL1 0.0055 0.0187 0.1291
Brugia malayi nuclear receptor NHR-88 0.0032 0.0078 0.0536
Schistosoma mansoni hypothetical protein 0.0028 0.0059 0.0059
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0124 0.0506 0.3508
Trypanosoma brucei Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0029 0.0188
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0194 0.0193
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0187 0.0187
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0101 0.0195
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0066 0.011
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0066 0.0464
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0209 0.0311
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0471 0.0753
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.01 0.0721
Loa Loa (eye worm) hypothetical protein 0.01 0.0394 0.2729
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0141 0.1026
Plasmodium falciparum iron-sulfur subunit of succinate dehydrogenase 0.005 0.0161 0.8641
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase iron-sulfur subunit 0.005 0.0161 1
Toxoplasma gondii TIM10 family protein, putative 0.0055 0.0186 0.3935
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0022 0.0033 0.1624
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0047 0.0147 0.0147
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0093 0.0223
Echinococcus multilocularis tumor protein p63 0.0335 0.1476 0.1476
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0047 0.0147 0.3121
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0149 0.7988
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0066 0.3424
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0167 0.0166
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Echinococcus granulosus dual specificity mitogen activated protein 0.0074 0.0273 0.0273
Brugia malayi Thioredoxin reductase 0.0047 0.0149 0.103
Brugia malayi hypothetical protein 0.0042 0.0126 0.0873
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0134 0.2834
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0101 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.013 0.0264
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0021 0.0029 0.0024
Schistosoma mansoni hypothetical protein 0.0821 0.3722 0.3722
Trypanosoma cruzi Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0029 0.0188
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0141 0.757
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0016 0.0016
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0022 0.0033 0.003
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0009 0.0057
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0131 0.0949
Echinococcus multilocularis caspase 8 0.0044 0.0134 0.0133
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0697 0.483
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0045 0.0141 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0078 0.0536
Echinococcus multilocularis RUN 0.002 0.0022 0.0021
Schistosoma mansoni loxhd1 0.002 0.0022 0.0022
Leishmania major hypothetical protein, conserved 0.0029 0.0066 0.0464
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0022 0.0033 0.0031
Leishmania major trypanothione reductase 0.0047 0.0149 0.1082
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0066 0.0065
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0149 0.0223
Leishmania major NADH dehydrogenase, putative 0.0033 0.0082 0.0582
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0019
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0151 0.015
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0131 0.0949
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0045 0.0141 0.0203
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0106 0.0422 0.0628
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0078 0.0536
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.002 0.0047
Echinococcus granulosus muscleblind protein 0.0172 0.0727 0.0726
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0022 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0101 0.0195
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0093 0.0223
Loa Loa (eye worm) doublecortin family protein 0.002 0.0022 0.0147
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.135 1
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.01 0.01
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0141 0.1026
Schistosoma mansoni cpg binding protein 0.0063 0.0222 0.0222
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0151 0.0151
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.002 0.0124
Loa Loa (eye worm) hypothetical protein 0.0172 0.0727 0.5038
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0078 0.0536
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0074 0.0523
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.01 0.01
Mycobacterium tuberculosis Probable oxidoreductase 0.0106 0.0422 0.0673
Toxoplasma gondii succinate dehydrogenase [ubiquinone] iron-sulfur protein 0.005 0.0161 0.341
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0021 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0141 0.0584 0.4046
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0047 0.0147 0.7896
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0592 0.0592
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0141 0.021
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0134 0.0924
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0066 0.0454
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0394 0.2729
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Schistosoma mansoni DNA helicase recq5 0.0029 0.0066 0.0066
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0141 0.021
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0009 0.0008
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0078 0.0077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0017 0.0017
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0022 0.0021
Brugia malayi Muscleblind-like protein 0.0172 0.0727 0.5038
Brugia malayi nuclear receptor RXR 0.0017 0.0009 0.0057
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.013 0.0898
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.002 0.0019
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0053 0.0053
Plasmodium falciparum glutathione reductase 0.0022 0.0033 0.1624
Onchocerca volvulus Huntingtin homolog 0.0141 0.0584 0.793
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0134 0.0273
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0151 0.8097
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0078 0.0077
Trichomonas vaginalis STE family protein kinase 0.0074 0.0273 0.0606
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.005 0.0161 0.016
Schistosoma mansoni polycystin 1-related 0.002 0.0022 0.0022
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0033 0.022
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0124 0.0503 0.3488
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) 0.0021 0.0029 0.0028
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0033 0.022
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0194 0.0194
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Trypanosoma cruzi metacaspase, putative 0.0044 0.0134 0.0969
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0078 0.0556
Brugia malayi hypothetical protein 0.0042 0.0126 0.0873
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0078 0.0536
Onchocerca volvulus Huntingtin homolog 0.0141 0.0584 0.793
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Echinococcus granulosus apoptotic protease activating factor 1 0.0076 0.0284 0.0284
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0592 0.0592
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0141 0.2995
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0113 0.5998
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0022 0.0033 0.003
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0078 0.0536
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0167 0.0167
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0032 0.0079 0.0078
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0078 0.0536
Loa Loa (eye worm) hypothetical protein 0.0039 0.0112 0.0772
Echinococcus multilocularis muscleblind protein 0.0172 0.0727 0.0726
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0176 0.1218
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0074 0.0523
Brugia malayi TAZ zinc finger family protein 0.0106 0.0423 0.2929
Brugia malayi hypothetical protein 0.0028 0.0059 0.0408
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0066 0.0464
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.002 0.0124
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.01 0.0721
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0022 0.0033 0.1624
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0224 0.1554
Mycobacterium leprae Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHY 0.0027 0.0058 0.0048
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0016 0.0092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Echinococcus multilocularis neuropeptide receptor A26 0.0471 0.2103 0.2103
Schistosoma mansoni succinate dehydrogenase 0.0021 0.0029 0.0029
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.0471 0.0706
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0078 0.0536
Brugia malayi jmjC domain containing protein 0.0058 0.02 0.1387
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0116 0.0466 0.0466
Mycobacterium tuberculosis Probable dehydrogenase 0.0096 0.0376 0.0598
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0009 0.0057
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0151 0.0314
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.002 0.0134
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0224 0.0224
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0032 0.0079 0.056
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0149 0.103
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Mycobacterium tuberculosis Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate deh 0.0027 0.0058 0.0073
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.002 0.0912
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0078 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0264 0.1826
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0158 0.0158
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0009 0.0009
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0022 0.0033 0.1624
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0115 0.0274
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase flavoprotein subunit 0.0021 0.0029 0.062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0078 0.0536
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0022 0.0021
Echinococcus multilocularis zinc finger protein 0.0029 0.0063 0.0063
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0451 0.2015 0.3172
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0055 0.0186 0.1285
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0078 0.105
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.013 0.0129
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0089 0.0638
Echinococcus multilocularis succinate dehydrogenase iron sulfur protein 0.0027 0.0058 0.0058
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0045 0.0141 0.0977
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0078 0.0536
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0078 0.0077
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0047 0.0147 0.1018
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0016 0.0015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.01 0.0193
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0078 0.0536
Brugia malayi mbt repeat family protein 0.0049 0.0155 0.1076
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0016 0.0015
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.02 0.02
Schistosoma mansoni lipoxygenase 0.0055 0.0184 0.0184
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0187 0.0186
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0057
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0175 0.1273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0078 0.0536
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0155 0.1076
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0101 0.07
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0131 0.0949
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0155 0.2109
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0016 0.0015
Echinococcus multilocularis CREB binding protein 0.0075 0.0277 0.0277
Trypanosoma cruzi ISWI complex protein 0.0016 0.0003 0.0001
Toxoplasma gondii flavoprotein subunit of succinate dehydrogenase 0.0021 0.0029 0.0605
Schistosoma mansoni alpha glucosidase 0.0037 0.0101 0.0101
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.002 0.001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0022 0.0033 0.022
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0155 0.0155
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0078 0.0536
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0167 0.0166
Echinococcus multilocularis CREB binding protein 0.0016 0.0007 0.0007
Echinococcus multilocularis CREB binding protein 0.0016 0.0007 0.0007
Trichomonas vaginalis STE family protein kinase 0.0074 0.0273 0.0606
Echinococcus multilocularis apoptotic protease activating factor 1 0.0076 0.0284 0.0284
Toxoplasma gondii hypothetical protein 0.005 0.016 0.3398
Giardia lamblia Kinase, STE STE20 0.0074 0.0273 0.0606
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Echinococcus granulosus zinc finger protein 0.0029 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0003
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.013 0.0129
Echinococcus multilocularis caspase 3 0.0072 0.0264 0.0263
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0101 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0134 0.0273
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0027 0.0058 0.0058
Loa Loa (eye worm) CBP-B 0.0076 0.0281 0.1947
Loa Loa (eye worm) hypothetical protein 0.0076 0.0284 0.1969
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0045 0.0141 0.0337
Giardia lamblia DINP protein human, muc B family 0.0021 0.0028 0.0019
Onchocerca volvulus 0.0049 0.0158 0.2137
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0078 0.0077
Echinococcus multilocularis caspase 2 0.012 0.0486 0.0486
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0167 0.1213
Toxoplasma gondii thioredoxin reductase 0.0047 0.0149 0.3157
Loa Loa (eye worm) translation initiation factor 4E 0.0035 0.0093 0.0645
Loa Loa (eye worm) hypothetical protein 0.0047 0.0147 0.1018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0078 0.0536
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0016 0.033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0106 0.0422 0.0673
Brugia malayi hypothetical protein 0.0017 0.0009 0.0057
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0093 0.067
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0167 0.0351
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0924 0.4196 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0496 0.0496
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0175 0.1208
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0022 0.0033 0.022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0452
Echinococcus multilocularis muscleblind protein 1 0.0172 0.0727 0.0726
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0631 0.0631
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0066 0.1392
Brugia malayi MAP kinase sur-1 0.0051 0.0167 0.1152
Loa Loa (eye worm) acetyltransferase 0.0152 0.0631 0.4378
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0078 0.0078
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0151 0.0151
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0194 0.0287
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0057
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0125 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0167 0.0351
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0454
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0028 0.0194
Schistosoma mansoni cpg binding protein 0.0063 0.0222 0.0222
Trypanosoma brucei unspecified product 0.0034 0.0089 0.0638
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0003 0.0003
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0631 0.4378
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0603 0.4452
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0147
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0035 0.0093 0.067
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0471 0.0753
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0022 0.0033 0.0033
Plasmodium falciparum metacaspase 1 0.0044 0.0134 0.7154
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0078 0.0536
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0134 0.7154
Echinococcus granulosus RUN 0.002 0.0022 0.0021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0451 0.2015 0.3188
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0012 0.0011
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0074 0.0273 0.1891
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0101 0.0728
Trypanosoma brucei glucosidase, putative 0.0037 0.0101 0.0728
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0078 0.0556
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0167 0.1213
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.002 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0405
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0167 0.0351
Echinococcus granulosus tumor protein p63 0.0335 0.1476 0.1476
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0116 0.0466 0.0466
Schistosoma mansoni zinc finger protein 0.0016 0.0003 0.0003
Echinococcus multilocularis dnaJ subfamily B 0.0821 0.3722 0.3722
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0924 0.4196 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0147
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1332 0.608 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.01 0.0721
Schistosoma mansoni rab6-interacting 0.002 0.0022 0.0022
Mycobacterium tuberculosis Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase) 0.0027 0.0058 0.0073
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0078 0.0077
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0101 0.07
Onchocerca volvulus 0.0032 0.0078 0.105
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0093 0.0176
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0016 0.0003
Loa Loa (eye worm) hypothetical protein 0.012 0.0486 0.3372
Schistosoma mansoni hypothetical protein 0.0076 0.0284 0.0284
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0022 0.0033 0.0032
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0053 0.0052
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.013 0.0898
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0821 0.3722 0.3722
Echinococcus multilocularis expressed conserved protein 0.0094 0.0366 0.0365
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0101 0.0195
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0016 0.0105
Loa Loa (eye worm) hypothetical protein 0.0124 0.0503 0.3488
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0003 0.0003
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0049 0.0155 0.1076
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0106 0.0423 0.0423
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0033 0.022
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0125 0.0863
Schistosoma mansoni rab6-interacting 0.002 0.0022 0.0022
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0093 0.0176
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0033 0.022
Mycobacterium tuberculosis Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase) 0.0021 0.0029 0.0024
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0016 0.0092
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1378 0.6289 1
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0141 0.1026
Echinococcus granulosus dna polymerase kappa 0.0041 0.0119 0.0119
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0078 0.105
Loa Loa (eye worm) hypothetical protein 0.0172 0.0727 0.5038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0078 0.0536
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0017 0.0017
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0078 0.0077
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0033 0.0082 0.0108
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0035 0.0093 0.067
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0134 0.2834
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0045 0.0141 0.0977
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0119 0.0168
Brugia malayi isocitrate dehydrogenase 0.0018 0.0016 0.0105
Toxoplasma gondii NADPH-glutathione reductase 0.0022 0.0033 0.0695
Echinococcus granulosus neuropeptide s receptor 0.0471 0.2103 0.2103
Onchocerca volvulus 0.0096 0.0374 0.5081
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0536
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0066 0.1398
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0134 0.0273
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0055 0.0186 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.01 0.2127
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0045 0.0141 0.0291
Chlamydia trachomatis succinate dehydrogenase iron sulfur subunit 0.0027 0.0058 1
Echinococcus granulosus expressed protein 0.0055 0.0186 0.0185
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0029 0.0195
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0083 0.0086
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0022 0.0033 0.1624
Echinococcus multilocularis dual specificity mitogen activated protein 0.0074 0.0273 0.0273
Onchocerca volvulus 0.002 0.0022 0.0288
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0003 0.0003
Trypanosoma brucei protein kinase, putative 0.0051 0.0167 0.1213
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0125 0.0251
Trypanosoma cruzi NADH dehydrogenase, putative 0.0033 0.0082 0.0582
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0022 0.0021
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0027 0.0058 0.0409
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0066 0.0065
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0101 0.0195
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0149 0.1082
Schistosoma mansoni bromodomain containing protein 0.0073 0.0269 0.0269
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0078 0.0078
Loa Loa (eye worm) succinate dehydrogenase iron-sulfur protein 0.005 0.0161 0.1113
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0401 0.0401
Brugia malayi hypothetical protein 0.0076 0.0284 0.1969
Loa Loa (eye worm) inositol-1 0.0037 0.01 0.0693
Trypanosoma brucei NADH dehydrogenase 0.0033 0.0082 0.0582
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0045 0.0141 0.0141
Schistosoma mansoni patched 1 0.0043 0.013 0.013
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0033 0.0082 0.4299
Brugia malayi Inositol-1 0.0037 0.01 0.0693
Onchocerca volvulus 0.002 0.0022 0.0288
Brugia malayi mbt repeat family protein 0.0049 0.0155 0.1076
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0055 0.0186 0.0186
Trypanosoma brucei ISWI complex protein 0.0016 0.0003 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0134 0.0273
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0047 0.0147 0.1018
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0047 0.0147 0.7896
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0078 0.0078
Brugia malayi hypothetical protein 0.0141 0.0584 0.4046
Schistosoma mansoni hypothetical protein 0.0041 0.0123 0.0123
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0066 0.0065
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0167 0.1213
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0119 0.0862
Plasmodium vivax iron-sulfur subunit of succinate dehydrogenase, putative 0.005 0.0161 0.8641
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0009 0.0057
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0451 0.2015 0.3299
Echinococcus granulosus neuropeptide receptor A26 0.0471 0.2103 0.2103

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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