Detailed information for compound 985103

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 291.733 | Formula: C14H14ClN3O2
  • H donors: 1 H acceptors: 2 LogP: 2.03 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccc(c(c1Cl)C)/N=C/1\OC[C@H]2N1CC[C@H]2O
  • InChi: 1S/C14H14ClN3O2/c1-8-10(3-2-9(6-16)13(8)15)17-14-18-5-4-12(19)11(18)7-20-14/h2-3,11-12,19H,4-5,7H2,1H3/b17-14-/t11-,12-/m1/s1
  • InChiKey: MNCIEDZVIIWLCH-QPEQGOCJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Androgen Receptor Starlite/ChEMBL References
Homo sapiens androgen receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0035 0.0025 0.011
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Schistosoma mansoni opsin-like receptor 0.0144 0.0436 0.0855
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.011 0.0308 0.6676
Brugia malayi Nuclear hormone receptor family member nhr-14 0.008 0.0194 0.0266
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0043 0.0057 0.0078
Echinococcus granulosus neuropeptide Y receptor 0.0144 0.0436 0.0435
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0043 0.0057 0.0078
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0034 0.0022 0.0277
Toxoplasma gondii microneme protein MIC17C 0.0172 0.054 0.0544
Echinococcus granulosus voltage gated potassium channel 0.0043 0.0057 0.0057
Plasmodium vivax importin-beta 2, putative 0.0028 0.0000063435 0.0003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.008 0.0194 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.008 0.0194 0.0266
Loa Loa (eye worm) hypothetical protein 0.0725 0.2618 0.3584
Brugia malayi G-protein coupled receptor 0.0144 0.0436 0.0596
Brugia malayi voltage-dependent calcium channel 0.0043 0.0057 0.0078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0036 0.0036
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0028 0.0028
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0055 0.0676
Schistosoma mansoni neuropeptide F-like receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0129 0.0254
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0077 0.0182 0.0249
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0256 0.0503
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1057 0.3867 0.3867
Onchocerca volvulus 0.0077 0.0183 0.1483
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0043 0.0057 0.0057
Schistosoma mansoni cpg binding protein 0.0029 0.0005 0.0009
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0346 0.2125
Brugia malayi Nuclear hormone receptor family member nhr-40 0.008 0.0194 0.0266
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0171 0.5819
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.269 1 1
Echinococcus granulosus hypothetical protein 0.0144 0.0436 0.0435
Brugia malayi GnHR receptor homolog 0.0144 0.0436 0.0596
Echinococcus multilocularis voltage gated potassium channel 0.0043 0.0057 0.0057
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0158 0.0158
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0057 0.0057
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0028 0.0875
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0102 0.0278 0.0278
Schistosoma mansoni hypothetical protein 0.0043 0.0057 0.0111
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0144 0.0436 0.0855
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0038 0.0036 0.0036
Echinococcus multilocularis transient receptor potential gamma protein 0.0043 0.0057 0.0057
Schistosoma mansoni protein kinase 0.0151 0.0463 0.091
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0144 0.0436 0.0855
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0436 0.0435
Schistosoma mansoni protein kinase 0.0151 0.0463 0.091
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0034 0.0022 0.0277
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni zinc finger protein 0.0038 0.0036 0.007
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Loa Loa (eye worm) glutathione reductase 0.0047 0.0072 0.0099
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Echinococcus multilocularis lysosomal alpha glucosidase 0.0332 0.1142 0.1142
Echinococcus granulosus ryanodine receptor 44f 0.0043 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0057 0.0111
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1973 0.7306 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0195 0.0383
Brugia malayi Cytochrome P450 family protein 0.0031 0.0012 0.0017
Toxoplasma gondii microneme protein MIC17A 0.0172 0.054 0.0544
Echinococcus multilocularis survival motor neuron protein 1 0.0725 0.2618 0.2618
Onchocerca volvulus 0.0144 0.0436 0.3662
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Onchocerca volvulus 0.01 0.0269 0.2224
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.03 0.1836
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0043 0.0057 0.0057
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0144 0.0436 0.0596
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0031 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.008 0.0195 0.0267
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0158 0.0929
Brugia malayi Pre-SET motif family protein 0.0031 0.0012 0.0016
Brugia malayi cation channel family protein 0.0043 0.0057 0.0078
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0036 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0144 0.0436 0.0596
Echinococcus multilocularis glycoprotein Antigen 5 0.008 0.0195 0.0195
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0109 0.0305 0.0305
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0034 0.0022 0.0277
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0144 0.0436 0.0855
Echinococcus granulosus dro:myosuppressin receptor 0.0144 0.0436 0.0435
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Echinococcus multilocularis potassium large conductance calcium activated 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0031 0.0009 0.0009
Trypanosoma cruzi 14-3-3 protein 2, putative 0.0034 0.0022 0.0222
Brugia malayi beta-lactamase family protein 0.007 0.0158 0.0216
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0158 0.1952
Echinococcus granulosus hyperpolarization activated cyclic 0.0043 0.0057 0.0057
Onchocerca volvulus 0.028 0.0946 0.8074
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0043 0.0057 0.0111
Schistosoma mansoni amine GPCR 0.0144 0.0436 0.0855
Leishmania major hypothetical protein, unknown function 0.0043 0.0057 0.0278
Schistosoma mansoni transient receptor potential channel 0.0043 0.0057 0.0111
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0038 0.0036 0.007
Mycobacterium tuberculosis Conserved protein 0.007 0.0158 0.0929
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0038 0.0036 0.0049
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0158 0.0929
Leishmania major trypanothione reductase 0.0047 0.0072 0.0376
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0012 0.0023
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0043 0.0057 0.0078
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0043 0.0057 0.0057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0195 0.0383
Brugia malayi neuropeptide F receptor 0.0144 0.0436 0.0596
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Echinococcus granulosus jun protein 0.0098 0.0262 0.0262
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0036 0.0146
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0036 0.0036
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0129 0.0177
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0043 0.0057 0.0057
Loa Loa (eye worm) G-protein coupled receptor 0.0144 0.0436 0.0596
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.008 0.0194 0.0194
Brugia malayi hypothetical protein 0.0038 0.0036 0.0049
Brugia malayi Trypsin family protein 0.008 0.0195 0.0267
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0036 0.007
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0436 0.0435
Schistosoma mansoni hypothetical protein 0.008 0.0193 0.038
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus multilocularis fmrfamide receptor 0.0144 0.0436 0.0435
Schistosoma mansoni hypothetical protein 0.0035 0.0025 0.005
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.008 0.0195 0.0383
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0144 0.0436 0.0596
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0171 0.2114
Echinococcus multilocularis voltage dependent calcium channel 0.0151 0.0461 0.0461
Brugia malayi putative neuropeptide receptor 0.0144 0.0436 0.0596
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0144 0.0436 0.0435
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0078 0.3567
Echinococcus granulosus 14-3-3 protein beta:alpha 0.0034 0.0022 0.0022
Toxoplasma gondii microneme protein MIC4 0.0172 0.054 0.0544
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0216
Echinococcus granulosus TRP transient receptor potential channel 0.0043 0.0057 0.0057
Brugia malayi Trypsin family protein 0.008 0.0195 0.0267
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.008 0.0194 0.0381
Schistosoma mansoni survival motor neuron protein 0.0148 0.045 0.0883
Schistosoma mansoni hypothetical protein 0.0441 0.1552 0.3046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0072 0.0099
Echinococcus granulosus G protein coupled receptor 139 0.0144 0.0436 0.0435
Brugia malayi Dopamine receptor 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.0215 0.0701 0.096
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Onchocerca volvulus 0.0144 0.0436 0.3662
Schistosoma mansoni deoxyribonuclease II-related 0.0073 0.0167 0.0329
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Echinococcus granulosus neuropeptides capa receptor 0.0144 0.0436 0.0435
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0044
Echinococcus granulosus transient receptor potential gamma protein 0.0043 0.0057 0.0057
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.044 0.0863
Loa Loa (eye worm) hypothetical protein 0.0339 0.1169 0.1601
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0046 0.0068 0.0068
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0215 0.0701 0.1376
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.0194 0.0194
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0144 0.0436 0.0435
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.238 0.8835 0.8835
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Onchocerca volvulus 0.0244 0.081 0.6896
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.008 0.0194 0.0194
Onchocerca volvulus 0.0144 0.0436 0.3662
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0195 0.0383
Schistosoma mansoni hypothetical protein 0.0301 0.1024 0.2009
Brugia malayi Trypsin-like protease protein 5 0.008 0.0195 0.0267
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0041 0.2275
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0171 0.2114
Schistosoma mansoni hypothetical protein 0.0144 0.0436 0.0855
Echinococcus granulosus sex peptide receptor 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Brugia malayi putative neuropeptide receptor NPR1 0.0144 0.0436 0.0596
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0171 0.2114
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0036 0.0036
Echinococcus granulosus neuropeptide receptor 0.0144 0.0436 0.0435
Echinococcus granulosus hypothetical protein 0.0043 0.0057 0.0057
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0158 0.0216
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0259 0.0866 0.0866
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni alpha glucosidase 0.0074 0.0171 0.0336
Echinococcus multilocularis G protein coupled receptor 139 0.0144 0.0436 0.0435
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Schistosoma mansoni growth hormone secretagogue receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0036 0.0049
Onchocerca volvulus 0.0038 0.0036 0.0208
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0043 0.0057 0.0111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Echinococcus multilocularis somatostatin receptor 0.0144 0.0436 0.0435
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0151 0.0461 0.0905
Brugia malayi Importin beta-1 subunit 0.0028 0.0000063435 0.000008683
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0078 0.1452
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Echinococcus granulosus microtubule associated protein 2 0.0673 0.2422 0.2422
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0057 0.0057
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0038 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Toxoplasma gondii kringle domain-containing protein 0.0074 0.0174 0.0175
Brugia malayi beta-lactamase family protein 0.007 0.0158 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0158 0.3246
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0151 0.0461 0.0461
Echinococcus multilocularis cpg binding protein 0.0029 0.0005 0.0004
Echinococcus granulosus voltage dependent calcium channel 0.0151 0.0461 0.0461
Brugia malayi Cyclic-nucleotide gated cation channel 0.0043 0.0057 0.0078
Brugia malayi nuclear receptor RXR 0.0042 0.0053 0.0072
Brugia malayi ecdysteroid receptor 0.008 0.0194 0.0266
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0158 0.0929
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.008 0.0194 0.0194
Brugia malayi hypothetical protein 0.008 0.0195 0.0267
Echinococcus multilocularis orexin receptor type 2 0.0144 0.0436 0.0435
Loa Loa (eye worm) G-protein coupled receptor 0.0144 0.0436 0.0596
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0144 0.0436 0.0596
Schistosoma mansoni serine-type protease inhibitor 0.1384 0.5095 1
Onchocerca volvulus 0.0048 0.0076 0.0554
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis SWI:SNF matrix associated 0.0077 0.0182 0.0182
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0158 0.1952
Echinococcus multilocularis adenylate cyclase type IX 0.0082 0.0201 0.0201
Mycobacterium tuberculosis Conserved protein 0.007 0.0158 0.0929
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0158 0.1952
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Onchocerca volvulus Protein ultraspiracle homolog 0.008 0.0194 0.1576
Brugia malayi sulfakinin receptor protein 0.0144 0.0436 0.0596
Onchocerca volvulus 0.008 0.0195 0.1585
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0036 0.0208
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0043 0.0057 0.0057
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.008 0.0194 0.0194
Echinococcus multilocularis neuropeptide receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis 14-3-3 protein zeta:delta 0.0034 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0025 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.008 0.0194 0.0266
Echinococcus granulosus neuropeptide receptor A26 0.1179 0.4322 0.4322
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Onchocerca volvulus 0.0172 0.054 0.4566
Brugia malayi Glutamate receptor 1 precursor 0.0031 0.0009 0.0013
Loa Loa (eye worm) cytochrome P450 0.0031 0.0012 0.0017
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Brugia malayi Cytochrome P450 family protein 0.0107 0.0296 0.0405
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0129 0.0129
Onchocerca volvulus 0.0172 0.054 0.4566
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0308 0.1858
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0009 0.0019
Loa Loa (eye worm) deoxyribonuclease II family protein 0.0073 0.0167 0.0229
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0043 0.0057 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0078 0.1452
Echinococcus multilocularis 0.0034 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0035 0.0025 0.011
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0009 0.0019
Schistosoma mansoni 60S ribosomal protein L21 0.0043 0.0057 0.0111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Schistosoma mansoni neuropeptide receptor 0.0144 0.0436 0.0855
Leishmania major cytochrome p450-like protein 0.0049 0.0078 0.041
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0061 0.0124 0.0124
Onchocerca volvulus 0.0259 0.0868 0.7401
Onchocerca volvulus 0.0058 0.0112 0.0871
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0108 0.0299 0.0409
Echinococcus multilocularis tissue type plasminogen activator 0.0074 0.0174 0.0174
Echinococcus granulosus tissue type plasminogen activator 0.0074 0.0174 0.0174
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Brugia malayi 14-3-3-like protein 2 0.0034 0.0022 0.0031
Echinococcus multilocularis sodium channel protein 0.0455 0.1602 0.1602
Schistosoma mansoni amine GPCR 0.0144 0.0436 0.0855
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0042 0.0053 0.0072
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Schistosoma mansoni calcium-activated potassium channel 0.0043 0.0057 0.0111
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0028 0.0351
Brugia malayi nuclear receptor NHR-88 0.008 0.0194 0.0266
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus multilocularis microtubule associated protein 2 0.0673 0.2422 0.2422
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0182 0.2244
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0044
Mycobacterium tuberculosis Probable reductase 0.0108 0.03 0.1836
Trypanosoma brucei calpain, putative 0.011 0.0308 0.6676
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.0308 0.6676
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0012 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0129 0.0254
Brugia malayi hypothetical protein 0.0725 0.2618 0.3584
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0151 0.0461 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0057 0.0057
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.008 0.0194 0.0381
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni inositol monophosphatase 0.0036 0.0028 0.0056
Onchocerca volvulus 0.0172 0.054 0.4566
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Schistosoma mansoni neuropeptide receptor 0.0144 0.0436 0.0855
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0171 0.2114
Echinococcus granulosus potassium large conductance calcium activated 0.0043 0.0057 0.0057
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Schistosoma mansoni hypothetical protein 0.0215 0.0701 0.1376
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0339 0.1169 0.2295
Echinococcus multilocularis shaker cognate 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0158 0.049 0.067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0256 0.0503
Echinococcus multilocularis tumor protein p63 0.0682 0.2456 0.2455
Brugia malayi hypothetical protein 0.0077 0.0183 0.0251
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.0308 0.6676
Onchocerca volvulus 0.008 0.0195 0.1585
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) steroid hormone receptor 0.008 0.0194 0.0266
Trypanosoma brucei 14-3-3 protein 1 0.0034 0.0022 0.0485
Onchocerca volvulus 0.0339 0.1169 1
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0158 0.0158
Trichomonas vaginalis deoxyribonuclease II, putative 0.0073 0.0167 0.2067
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0057 0.0111
Echinococcus multilocularis dro:myosuppressin receptor 0.0144 0.0436 0.0435
Toxoplasma gondii PAN domain-containing protein 0.2671 0.993 1
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0046 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.008 0.0194 0.0266
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0057 0.0057
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0034 0.0022 0.0277
Brugia malayi tailless protein 0.0038 0.0036 0.0049
Brugia malayi Glycosyl hydrolases family 31 protein 0.0332 0.1142 0.1564
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0436 0.0855
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0455 0.1602 0.1602
Loa Loa (eye worm) cytochrome P450 family protein 0.0107 0.0296 0.0405
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0129 0.0254
Schistosoma mansoni apoptosis regulator bax 0.0215 0.0701 0.1376
Brugia malayi follicle stimulating hormone receptor 0.0144 0.0436 0.0596
Onchocerca volvulus 0.0172 0.054 0.4566
Loa Loa (eye worm) RNA binding protein 0.0063 0.0129 0.0177
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0057 0.0111
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0151 0.0461 0.0461
Schistosoma mansoni hypothetical protein 0.008 0.0195 0.0383
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0144 0.0436 0.0855
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0053 0.0103
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0036 0.196
Brugia malayi Thioredoxin reductase 0.0047 0.0072 0.0099
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0441 0.1552 0.1552
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0346 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0171 0.0171
Echinococcus granulosus tumor protein p63 0.0682 0.2456 0.2455
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0036 0.007
Trichomonas vaginalis esterase, putative 0.007 0.0158 0.1952
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0346 0.2125
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Plasmodium vivax hypothetical protein, conserved 0.007 0.0158 0.8698
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0036 0.1268
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0072
Schistosoma mansoni opsin-like receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) inositol-1 0.0036 0.0028 0.0039
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0215 0.0701 0.096
Schistosoma mansoni retinoic acid receptor RXR 0.008 0.0194 0.0381
Trypanosoma brucei calpain-like protein, putative 0.011 0.0308 0.6676
Echinococcus granulosus 14-3-3 protein epsilon 0.0034 0.0022 0.0022
Brugia malayi nuclear hormone receptor 0.0038 0.0036 0.0049
Schistosoma mansoni steroid hormone receptor ad4bp 0.008 0.0194 0.0381
Echinococcus granulosus nuclear receptor nhr 48 0.0038 0.0036 0.0036
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0055 0.0676
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Schistosoma mansoni nuclear receptor 0.0038 0.0036 0.007
Leishmania major hypothetical protein, conserved 0.0043 0.0057 0.0278
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Loa Loa (eye worm) trypsin family protein 0.008 0.0195 0.0267
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.008 0.0195 0.0267
Schistosoma mansoni nuclear receptor 0.0038 0.0036 0.007
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0043 0.0057 0.0057
Toxoplasma gondii microneme protein MIC17B 0.0172 0.054 0.0544
Trichomonas vaginalis deoxyribonuclease II precursor, putative 0.0073 0.0167 0.2067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0068 0.0068
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0144 0.0436 0.0435
Schistosoma mansoni alpha-1 adrenergic receptor 0.0144 0.0436 0.0855
Brugia malayi Dopamine receptor protein 1 0.0144 0.0436 0.0596
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0036 0.0049
Schistosoma mansoni ap endonuclease 0.0038 0.0036 0.007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0144 0.0436 0.0596
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0144 0.0436 0.0855
Schistosoma mansoni neuropeptide receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) hypothetical protein 0.008 0.0195 0.0267
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.03 0.864
Loa Loa (eye worm) hypothetical protein 0.0151 0.0461 0.0631
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0256 0.0351
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0161 0.0499 0.4209
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0278 0.0546
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0144 0.0436 0.0435
Leishmania major 14-3-3 protein, putative 0.0034 0.0022 0.0063
Schistosoma mansoni two-pore calcium channel 0.0043 0.0057 0.0111
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0195 0.0383
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0216
Loa Loa (eye worm) hypothetical protein 0.0519 0.1845 0.2525
Brugia malayi neuropeptide F receptor 0.0144 0.0436 0.0596
Schistosoma mansoni histamine h1 receptor 0.0144 0.0436 0.0855
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0455 0.1602 1
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0053 0.0072
Brugia malayi Serotonin receptor 0.0144 0.0436 0.0596
Toxoplasma gondii hypothetical protein 0.0043 0.0057 0.0057
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0028 0.0616
Echinococcus multilocularis 14-3-3 protein epsilon 0.0034 0.0022 0.0022
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Echinococcus granulosus retinoic acid receptor rxr beta a 0.008 0.0194 0.0194
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.0308 0.6676
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0031 0.0012 0.0269
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0077 0.0182 1
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0057 0.0057
Brugia malayi Deoxyribonuclease II family protein 0.0073 0.0167 0.0229
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0036 0.0208
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0144 0.0436 0.0435
Schistosoma mansoni RAR-like nuclear receptor 0.008 0.0194 0.0381
Brugia malayi Adenylyl cyclase protein 0.0058 0.0112 0.0154
Brugia malayi Steroid receptor seven-up type 2 0.008 0.0194 0.0266
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0057 0.0057
Brugia malayi map kinase activated protein kinase protein 2 0.0185 0.0588 0.0805
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0043 0.0057 0.0057
Echinococcus granulosus neuropeptide FF receptor 2 0.0144 0.0436 0.0435
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0057 0.0057
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0077 0.0182 0.0182
Toxoplasma gondii PAN domain-containing protein 0.0172 0.054 0.0544
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0036 0.0029 0.0057
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0043 0.0057 0.0078
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0144 0.0436 0.0435
Mycobacterium leprae conserved hypothetical protein 0.007 0.0158 0.4372
Loa Loa (eye worm) glutamate receptor 2 0.0031 0.0009 0.0013
Echinococcus granulosus GPCR family 2 0.0441 0.1552 0.1552
Brugia malayi G protein-coupled receptor 0.0144 0.0436 0.0596
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0031 0.0009 0.0009
Echinococcus multilocularis 0.0031 0.0012 0.0012
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0057 0.0699
Loa Loa (eye worm) PAN domain-containing protein 0.0172 0.054 0.0739
Brugia malayi larval opioid receptor 0.0144 0.0436 0.0596
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0098 0.0262 0.0262
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0025 0.0025
Leishmania major hypothetical protein, conserved 0.0074 0.0174 0.1014
Brugia malayi Glutamate receptor 2 precursor 0.0031 0.0009 0.0013
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0068 0.0068
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0185 0.0588 0.0588
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0436 0.0435
Schistosoma mansoni hypothetical protein 0.0074 0.0174 0.0341
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0038 0.0036 0.0049
Echinococcus multilocularis ryanodine receptor 44f 0.0043 0.0057 0.0057
Trypanosoma cruzi 14-3-3 protein 2, putative 0.0034 0.0022 0.0222
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0171 0.3538
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0278 0.3433
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0077 0.0182 0.0357
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0072
Schistosoma mansoni hypothetical protein 0.0144 0.0436 0.0855
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0215 0.0701 0.1376
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0057 0.0111
Loa Loa (eye worm) deoxyribonuclease II family protein 0.0073 0.0167 0.0229
Entamoeba histolytica hypothetical protein 0.0035 0.0025 0.011
Echinococcus granulosus neuropeptides capa receptor 0.0144 0.0436 0.0435
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.012 0.0235
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0072
Echinococcus multilocularis hyperpolarization activated cyclic 0.0043 0.0057 0.0057
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0043 0.0057 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0144 0.0436 0.0435
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0072 0.0381
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis FTZ F1 alpha 0.008 0.0194 0.0194
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.0308 0.6676
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0256 0.0256
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0057 0.0057
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Echinococcus granulosus voltage gated potassium channel 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Toxoplasma gondii hypothetical protein 0.0043 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.008 0.0195 0.0383
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0441 0.1552 0.2124
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus granulosus two pore calcium channel protein 1 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0171 0.0171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.0194 0.0194
Echinococcus multilocularis neuropeptide Y receptor 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0216
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0038 0.0036 0.0036
Echinococcus granulosus glutamate receptor subunit protein glur 0.0031 0.0009 0.0009
Onchocerca volvulus 0.007 0.0158 0.1265
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Brugia malayi brahma associated protein 60 kDa 0.0077 0.0182 0.0249
Echinococcus multilocularis neuropeptide FF receptor 2 0.0144 0.0436 0.0435
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0079 0.019 0.9694
Loa Loa (eye worm) ryanodine receptor 0.0043 0.0057 0.0078
Echinococcus granulosus lysosomal alpha glucosidase 0.0332 0.1142 0.1142
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Echinococcus granulosus fmrfamide receptor 0.0144 0.0436 0.0435
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0036 0.0036
Schistosoma mansoni voltage-gated ion channel 0.0043 0.0057 0.0111
Mycobacterium leprae Probable lipase LipE 0.007 0.0158 0.4372
Schistosoma mansoni hypothetical protein 0.0215 0.0701 0.1376
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0057 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0012 0.0023
Schistosoma mansoni alpha-glucosidase 0.0286 0.0969 0.1901
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0042 0.0053 0.0053
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0308 0.6584
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.008 0.0194 0.0381
Brugia malayi Transient-receptor-potential like protein 0.0043 0.0057 0.0078
Echinococcus granulosus tachykinin peptides receptor 99D 0.0144 0.0436 0.0435
Echinococcus multilocularis transfer RNA-Gly 0.0043 0.0057 0.0057
Onchocerca volvulus 0.0144 0.0436 0.3662
Schistosoma mansoni hypothetical protein 0.0108 0.03 0.0589
Toxoplasma gondii PAN/Apple domain-containing protein 0.0172 0.054 0.0544
Brugia malayi AKH receptor 0.0144 0.0436 0.0596
Schistosoma mansoni glutamate receptor NMDA 0.0046 0.0068 0.0134
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0144 0.0436 0.0435
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0078 0.0106
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0057 0.0057
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0038 0.0036 0.007
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0151 0.0461 0.0461
Toxoplasma gondii exonuclease III APE 0.0038 0.0036 0.0036
Trypanosoma brucei RNA helicase, putative 0.0108 0.03 0.651
Echinococcus multilocularis NMDA receptor 0.0031 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus granulosus deoxyribonuclease ii 0.0073 0.0167 0.0167
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0436 0.0435
Schistosoma mansoni protein kinase 0.0151 0.0463 0.091
Echinococcus granulosus 7tm_1 domain containing protein 0.0144 0.0436 0.0435
Onchocerca volvulus 0.008 0.0194 0.1576
Echinococcus multilocularis serotonin receptor 0.0144 0.0436 0.0435
Brugia malayi 14-3-3-like protein 2 0.0034 0.0022 0.0031
Echinococcus multilocularis 14-3-3 protein beta:alpha 0.0034 0.0022 0.0022
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0072 0.0072
Echinococcus granulosus snurportin 1 0.0301 0.1024 0.1024
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0044
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0042 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0043 0.0057 0.0078
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0132 0.0389 0.0533
Brugia malayi hypothetical protein 0.0042 0.0053 0.0072
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0074 0.0174 0.9551
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.03 0.1836
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.044 0.0602
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0028 0.0235
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0055 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-31 0.008 0.0194 0.0266
Echinococcus multilocularis neuropeptide receptor A26 0.1179 0.4322 0.4322
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0151 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.0057 0.0057
Trypanosoma brucei 14-3-3 protein 2 0.0034 0.0022 0.0485
Brugia malayi beta-lactamase 0.007 0.0158 0.0216
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0014 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0036 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0256 0.0256
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0036 0.0049
Loa Loa (eye worm) voltage-dependent calcium channel 0.0151 0.0461 0.0631
Brugia malayi ion channel NompC 0.0043 0.0057 0.0078
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.008 0.0194 0.0194
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0346 0.2125
Schistosoma mansoni hypothetical protein 0.0915 0.3333 0.6542
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0077 0.0182 1
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0436 0.0435
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0057 0.0111
Onchocerca volvulus 0.0148 0.045 0.3785
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis nuclear receptor nhr 48 0.0038 0.0036 0.0036
Brugia malayi Calcitonin receptor-like protein seb-1 0.1357 0.4991 0.6832
Loa Loa (eye worm) melatonin receptor type 1A 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0043 0.0057 0.0078
Brugia malayi Serotonin receptor 0.0144 0.0436 0.0596
Loa Loa (eye worm) ion channel NompC 0.0043 0.0057 0.0078
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0043 0.0057 0.0057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0195 0.0383
Schistosoma mansoni ap endonuclease 0.0038 0.0036 0.007
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.044 0.044
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0057 0.0057
Schistosoma mansoni vesicular amine transporter 0.0043 0.0057 0.0111
Schistosoma mansoni nuclear hormone receptor 0.008 0.0194 0.0381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.008 0.0194 0.0266
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0043 0.0057 0.0389
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0436 0.0855
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0043 0.0057 0.0078
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0129 0.0177
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0151 0.0461 0.0461
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Brugia malayi hypothetical protein 0.0043 0.0057 0.0078
Onchocerca volvulus Neuropeptide F receptor homolog 0.0144 0.0436 0.3662
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0449 0.158 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0171 0.5819
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0009 0.0019
Schistosoma mansoni biogenic amine receptor 0.0144 0.0436 0.0855
Brugia malayi SWIB/MDM2 domain containing protein 0.0077 0.0182 0.0249
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0172 0.054 0.0544
Onchocerca volvulus 0.0077 0.0182 0.147
Echinococcus multilocularis fmrfamide receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis transmembrane protease serine 3 0.008 0.0195 0.0195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Onchocerca volvulus 0.0144 0.0436 0.3662
Schistosoma mansoni serine-type protease inhibitor 0.1384 0.5095 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0038 0.0036 0.0049
Loa Loa (eye worm) TK/ROR protein kinase 0.0074 0.0174 0.0238
Schistosoma mansoni ryanodine receptor related 0.0043 0.0057 0.0111
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0308 0.6584
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0216
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0278 0.3433
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni thyroid hormone receptor 0.008 0.0194 0.0381
Brugia malayi Melatonin receptor type 1A 0.0144 0.0436 0.0596
Mycobacterium ulcerans hypothetical protein 0.008 0.0195 1
Echinococcus granulosus g protein coupled receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis Mastin 0.008 0.0195 0.0195
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.011 0.0308 0.6676
Echinococcus multilocularis two pore calcium channel protein 1 0.0043 0.0057 0.0057
Echinococcus granulosus 14-3-3 protein zeta:delta 0.0034 0.0022 0.0022
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0043 0.0057 0.0057
Brugia malayi brahma associated protein 60 kDa 0.0077 0.0182 0.0249
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0031 0.0009 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0028 0.0356
Brugia malayi nuclear hormone receptor family member odr-7 0.0038 0.0036 0.0049
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0057 0.0057
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0132 0.0389 0.0533
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0148 0.045 0.0883
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.0057 0.0057
Schistosoma mansoni amine GPCR 0.0144 0.0436 0.0855
Brugia malayi glutathione reductase 0.0047 0.0072 0.0099
Onchocerca volvulus 0.0172 0.054 0.4566
Brugia malayi Nuclear hormone receptor family member nhr-3 0.008 0.0194 0.0266
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0043 0.0057 0.0057
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.008 0.0195 0.0195
Brugia malayi Protein kinase domain containing protein 0.0074 0.0174 0.0238
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0043 0.0057 0.0078
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0077 0.0182 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0036 0.6979
Echinococcus granulosus tar DNA binding protein 0.0063 0.0129 0.0129
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Mycobacterium tuberculosis Conserved protein 0.007 0.0158 0.0929
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Schistosoma mansoni hypothetical protein 0.0441 0.1552 0.3046
Loa Loa (eye worm) latrophilin receptor protein 2 0.0441 0.1552 0.2124
Echinococcus multilocularis adenylate cyclase 9 0.0058 0.0112 0.0112
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0215 0.0701 0.0701
Brugia malayi nuclear receptor NHR-67 0.0038 0.0036 0.0049
Echinococcus multilocularis voltage gated potassium channel 0.0043 0.0057 0.0057
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0332 0.1142 0.1564
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.008 0.0194 0.0194
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0158 0.7975
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0031 0.0009 0.0009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0645 0.2319 0.2319
Trypanosoma cruzi calpain cysteine peptidase, putative 0.011 0.0308 0.6584
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0436 0.0435
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0425 0.0425
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0057 0.0111
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0043 0.0057 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0278 0.3433
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Loa Loa (eye worm) hypothetical protein 0.008 0.0195 0.0267
Brugia malayi ecdysone receptor 0.0038 0.0036 0.0049
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0061 0.0124 0.0124
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.008 0.0195 0.0195
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0151 0.0463 0.0463
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0078 0.0106
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.0194 0.0194
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0102 0.0278 0.0381
Echinococcus granulosus glutamate receptor 2 0.0046 0.0068 0.0068
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0079 0.019 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0012 0.0012
Schistosoma mansoni ATP-binding cassette transporter 0.0031 0.0009 0.0019
Loa Loa (eye worm) nuclear hormone receptor 0.0038 0.0036 0.0049
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0077 0.0182 0.0183
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0043 0.0057 0.0078
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0057 0.0057
Echinococcus granulosus neuropeptide s receptor 0.1179 0.4322 0.4322
Brugia malayi Kringle domain containing protein 0.0074 0.0174 0.0238
Echinococcus multilocularis serotonin receptor 0.0144 0.0436 0.0435
Schistosoma mansoni brg-1 associated factor 0.0077 0.0182 0.0357
Toxoplasma gondii subtilisin SUB12 0.0172 0.054 0.0544
Echinococcus granulosus cytochrome P450 2K1 0.0031 0.0012 0.0012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0144 0.0436 0.0855
Toxoplasma gondii hypothetical protein 0.0172 0.054 0.0544
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0308 0.6584
Plasmodium vivax SET domain protein, putative 0.0031 0.0012 0.0641
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Brugia malayi steroid hormone receptor 0.008 0.0194 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-1 0.008 0.0194 0.0266
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0028 0.0356
Brugia malayi Caveolin-1 0.0519 0.1845 0.2525
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0072 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0171 0.3538
Echinococcus multilocularis 14-3-3 protein 0.0034 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0588 0.1154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0144 0.0436 0.0596
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0043 0.0057 0.0057
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0305 0.0305
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0098 0.0262 0.0262
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0043 0.0057 0.0111
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Loa Loa (eye worm) neuropeptide F receptor 0.0144 0.0436 0.0596
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0036 0.0772
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Loa Loa (eye worm) beta-lactamase 0.007 0.0158 0.0216
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.0057 0.0057
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0158 0.7975
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0077 0.0182 0.0182
Loa Loa (eye worm) bone morphogenic protein 6 0.0061 0.0124 0.017
Echinococcus multilocularis neuropeptides capa receptor 0.0144 0.0436 0.0435
Brugia malayi Latrophilin receptor protein 2 0.0441 0.1552 0.2124
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Trypanosoma cruzi 14-3-3 protein 1, putative 0.0034 0.0022 0.0222
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0144 0.0436 0.0855
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0036 0.0036
Loa Loa (eye worm) PAN domain-containing protein 0.0172 0.054 0.0739
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0144 0.0436 0.0855
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0144 0.0436 0.0855
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1057 0.3867 0.3867
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0044
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0057 0.0111
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0171 0.2114
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0057 0.0111
Brugia malayi nuclear receptor RXR 0.0038 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0000063435 0.000008683
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0043 0.0057 0.0057
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.03 0.1836
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0144 0.0436 0.0435
Onchocerca volvulus 0.0056 0.0103 0.079
Toxoplasma gondii transporter, cation channel family protein 0.0043 0.0057 0.0057
Echinococcus granulosus peptide allatostatin:somatostatin 0.0144 0.0436 0.0435
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0014 0.0057
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0055 0.0055
Toxoplasma gondii 14-3-3 protein 0.0034 0.0022 0.0023
Plasmodium vivax glutathione reductase, putative 0.0047 0.0072 0.3975
Echinococcus granulosus sodium leak channel non selective protein 0.0043 0.0057 0.0057
Echinococcus multilocularis hyperpolarization activated cyclic 0.0043 0.0057 0.0057
Schistosoma mansoni neuropeptide f receptor 76f 0.0144 0.0436 0.0855
Brugia malayi TAR-binding protein 0.0063 0.0129 0.0177
Echinococcus granulosus SWI:SNF matrix associated 0.0077 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.028 0.0946 0.1295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0256 0.0503
Schistosoma mansoni amine GPCR 0.0144 0.0436 0.0855
Entamoeba histolytica protein kinase, putative 0.0102 0.0278 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0057 0.0057
Loa Loa (eye worm) calcium channel 0.0151 0.0461 0.0631
Schistosoma mansoni transient receptor potential channel 0.0043 0.0057 0.0111
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0057 0.0078
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0012 0.0012
Echinococcus granulosus serotonin receptor 0.0144 0.0436 0.0435
Echinococcus granulosus orexin receptor type 2 0.0144 0.0436 0.0435
Toxoplasma gondii PAN domain-containing protein 0.0172 0.054 0.0544
Brugia malayi Trypsin family protein 0.008 0.0195 0.0267
Echinococcus multilocularis allatostatin A receptor 0.028 0.0946 0.0946
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.008 0.0194 0.0266
Loa Loa (eye worm) hypothetical protein 0.0108 0.0299 0.0409
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Echinococcus granulosus g protein coupled receptor 0.0144 0.0436 0.0435
Brugia malayi Cytochrome P450 family protein 0.0049 0.0078 0.0106
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus granulosus survival motor neuron protein 1 0.0725 0.2618 0.2618
Brugia malayi Tachykinin-like peptides receptor 99D 0.0144 0.0436 0.0596
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0043 0.0057 0.0078
Schistosoma mansoni hypothetical protein 0.0441 0.1552 0.3046
Echinococcus granulosus glutamate NMDA receptor subunit 0.0259 0.0866 0.0866
Toxoplasma gondii PAN domain-containing protein 0.0172 0.054 0.0544
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0036 0.0036
Trypanosoma brucei glucosidase, putative 0.0074 0.0171 0.3712
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Brugia malayi photoreceptor-specific nuclear receptor 0.008 0.0194 0.0266
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0158 0.0929
Brugia malayi latrophilin 2 splice variant baaae 0.0915 0.3333 0.4562
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0151 0.0461 1
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0269 0.0528
Onchocerca volvulus 0.0172 0.054 0.4566
Echinococcus multilocularis neuropeptide receptor 0.0144 0.0436 0.0435
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0036 0.0036
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.03 0.1836
Echinococcus multilocularis 14-3-3 protein 0.0034 0.0022 0.0022
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0151 0.0461 0.0461
Echinococcus multilocularis sex peptide receptor 0.0144 0.0436 0.0435
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0129 0.0254
Loa Loa (eye worm) DR-78 0.0038 0.0036 0.0049
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0308 0.1858
Echinococcus granulosus two pore calcium channel protein 2 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni amine GPCR 0.0144 0.0436 0.0855
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.008 0.0194 0.1576
Echinococcus multilocularis jun protein 0.0098 0.0262 0.0262
Brugia malayi Transforming growth factor beta like domain containing protein 0.0061 0.0124 0.017
Schistosoma mansoni neuropeptide F-like receptor 0.0144 0.0436 0.0855
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0041 0.074
Plasmodium falciparum 14-3-3 protein 0.0034 0.0022 0.1234
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0144 0.0436 0.0435
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0436 0.0435
Brugia malayi bZIP transcription factor family protein 0.0098 0.0262 0.0359
Onchocerca volvulus 0.0144 0.0436 0.3662
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0171 0.0234
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.1024 0.1401
Schistosoma mansoni transient receptor potential channel 0.0043 0.0057 0.0111
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0171 0.0234
Brugia malayi hypothetical protein 0.0042 0.0053 0.0072
Schistosoma mansoni adenoreceptor 0.0144 0.0436 0.0855
Echinococcus multilocularis GPCR, family 2 0.0441 0.1552 0.1552
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0144 0.0436 0.0435
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0256 0.0351
Echinococcus granulosus voltage gated hydrogen channel 1 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0057 0.0057
Loa Loa (eye worm) voltage-gated calcium channel 0.0043 0.0057 0.0078
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0042 0.0053 0.0103
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Brugia malayi PAN domain containing protein 0.0172 0.054 0.0739
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.008 0.0194 0.0266
Onchocerca volvulus 0.008 0.0195 0.1585
Onchocerca volvulus 0.0043 0.0057 0.0389
Brugia malayi phosphoinositide-dependent protein kinase I 0.0102 0.0278 0.0381
Onchocerca volvulus 0.0172 0.054 0.4566
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0171 0.2114
Brugia malayi Trypsin family protein 0.0339 0.1169 0.1601
Brugia malayi olfactory channel protein osm-9 0.0043 0.0057 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0036 0.044
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0072 0.3975
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni thyroid hormone receptor 0.008 0.0194 0.0381
Loa Loa (eye worm) hypothetical protein 0.0441 0.1552 0.2124
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0057 0.0699
Schistosoma mansoni jun-related protein 0.008 0.0193 0.038
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0171 0.2114
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0079 0.019 0.1129
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0057 0.0057
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0078 0.1682
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0043 0.0057 0.0078
Echinococcus granulosus adenylate cyclase type IX 0.0082 0.0201 0.0201
Echinococcus multilocularis neuropeptide s receptor 0.1179 0.4322 0.4322
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0436 0.0855
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.03 0.1836
Schistosoma mansoni nuclear receptor nhr-48 0.0038 0.0036 0.007
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Brugia malayi nuclear hormone receptor 0.008 0.0194 0.0266
Echinococcus granulosus hyperpolarization activated cyclic 0.0043 0.0057 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) neuropeptide F receptor 0.0144 0.0436 0.0596
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0028 0.0351
Leishmania major hypothetical protein, conserved 0.007 0.0158 0.0916
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0043 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0077 0.0182 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-25 0.008 0.0194 0.0266
Brugia malayi hypothetical protein 0.0035 0.0025 0.0035
Schistosoma mansoni inositol monophosphatase 0.0036 0.0028 0.0056
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0144 0.0436 0.0435
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0036 0.196
Brugia malayi cation channel family protein 0.0043 0.0057 0.0078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0436 0.0855
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0057 0.0057
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0171 0.2114
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0215 0.0701 0.0701
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.008 0.0194 0.0194
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0194 0.0266
Loa Loa (eye worm) hypothetical protein 0.0339 0.1169 0.1601
Loa Loa (eye worm) PAN domain-containing protein 0.0172 0.054 0.0739
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0158 0.1952
Echinococcus multilocularis snurportin 1 0.0301 0.1024 0.1024
Loa Loa (eye worm) hypothetical protein 0.0095 0.0252 0.0345
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.008 0.0195 0.0195
Echinococcus granulosus FTZ F1 alpha 0.008 0.0194 0.0194
Echinococcus multilocularis calcium activated potassium channel 0.0045 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Echinococcus multilocularis g-protein coupled receptor 0.0144 0.0436 0.0435
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0171 0.2114
Brugia malayi orphan nuclear receptor NR2E1 0.0038 0.0036 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-19 0.008 0.0194 0.0266
Loa Loa (eye worm) TYRA-2 protein 0.0144 0.0436 0.0596
Brugia malayi cytochrome P450 0.0031 0.0012 0.0017
Echinococcus granulosus g-protein coupled receptor 0.0144 0.0436 0.0435
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0057 0.0057
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0144 0.0436 0.3662
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0036 0.0148
Toxoplasma gondii thioredoxin reductase 0.0047 0.0072 0.0073
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0216
Mycobacterium ulcerans lipase LipD 0.007 0.0158 0.7975
Brugia malayi conserved hypotetical protein 0.0038 0.0036 0.0049
Echinococcus granulosus g protein coupled receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0129 0.0177
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Echinococcus multilocularis SWI:SNF matrix associated 0.0077 0.0182 0.0182
Brugia malayi Protein kinase domain containing protein 0.0102 0.0278 0.0381
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0036 0.0516
Echinococcus multilocularis lysosomal alpha glucosidase 0.0332 0.1142 0.1142
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.008 0.0195 0.0267
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Echinococcus granulosus 7TM GPCR rhodopsin 0.0144 0.0436 0.0435
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0151 0.0461 0.0461
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0043 0.0057 0.0078
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.008 0.0194 0.0266
Entamoeba histolytica hypothetical protein 0.0035 0.0025 0.011
Plasmodium falciparum importin beta, putative 0.0028 0.0000063435 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0129 0.0254
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0031 0.0009 0.0009
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0068 0.0068
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0057 0.0057
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0441 0.1552 0.1552
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0144 0.0436 0.0435
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.0172 0.054 0.0739
Loa Loa (eye worm) hypothetical protein 0.0151 0.0461 0.0631
Echinococcus multilocularis sodium leak channel non selective protein 0.0043 0.0057 0.0057
Trichomonas vaginalis set domain proteins, putative 0.0244 0.081 1
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0174 0.3592
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0043 0.0057 0.0057
Echinococcus granulosus neuropeptide receptor 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0043 0.0057 0.0057
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0043 0.0057 0.0389
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0057 0.0111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0012 0.0023
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.008 0.0195 0.0267
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0072 0.1333
Loa Loa (eye worm) acetyltransferase 0.0145 0.044 0.0602
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0144 0.0436 0.0596
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.01 0.0269 0.0368
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0144 0.0436 0.0596
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0058 0.0112 0.0871
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0079 0.019 1
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Onchocerca volvulus 0.0172 0.054 0.4566
Echinococcus multilocularis glutamate receptor 2 0.0031 0.0009 0.0009
Brugia malayi Pre-SET motif family protein 0.0214 0.0699 0.0957
Schistosoma mansoni cpg binding protein 0.0029 0.0005 0.0009
Loa Loa (eye worm) PAN domain-containing protein 0.0172 0.054 0.0739
Loa Loa (eye worm) PAN domain-containing protein 0.0172 0.054 0.0739
Schistosoma mansoni biogenic amine receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Schistosoma mansoni cytochrome P450 0.0031 0.0012 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.0194 0.0381
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0102 0.0278 0.0278
Echinococcus multilocularis SWI:SNF matrix associated 0.0077 0.0182 0.0182
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0158 0.031
Echinococcus multilocularis voltage dependent calcium channel 0.0151 0.0461 0.0461
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0158 0.3246
Toxoplasma gondii cytochrome p450 superfamily protein 0.0031 0.0012 0.0013
Schistosoma mansoni opsin-like receptor 0.0144 0.0436 0.0855
Onchocerca volvulus 0.008 0.0195 0.1585
Brugia malayi Inositol-1 0.0036 0.0028 0.0039
Echinococcus granulosus glycoprotein Antigen 5 0.008 0.0195 0.0195
Onchocerca volvulus Bile acid receptor homolog 0.008 0.0194 0.1576
Echinococcus granulosus alpha 1A adrenergic receptor 0.0144 0.0436 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0436 0.0435
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0185 0.0588 0.0805
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0436 0.0435
Echinococcus multilocularis G-protein coupled receptor, putative 0.0144 0.0436 0.0435
Schistosoma mansoni transient receptor potential channel 4 0.0043 0.0057 0.0111
Trichomonas vaginalis DNAse2-prov protein, putative 0.0073 0.0167 0.2067
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0308 0.6584
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-25 0.008 0.0194 0.0266
Schistosoma mansoni peptide (allatostatin)-like receptor 0.028 0.0946 0.1857
Echinococcus granulosus adenylate cyclase 9 0.0058 0.0112 0.0112
Onchocerca volvulus 0.007 0.0158 0.1265
Plasmodium falciparum cysteine repeat modular protein 1 0.0074 0.0174 0.9551
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0036 0.0049
Onchocerca volvulus 0.0074 0.0174 0.1399
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Toxoplasma gondii transporter, cation channel family protein 0.0043 0.0057 0.0057
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0102 0.0278 0.0381
Schistosoma mansoni microtubule-associated protein tau 0.0673 0.2422 0.4755
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0151 0.0461 0.0905
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0144 0.0436 0.0596
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0028 0.0351
Toxoplasma gondii ABC1 family protein 0.007 0.0158 0.0159
Brugia malayi Dopamine receptor protein 2 0.0144 0.0436 0.0596
Echinococcus granulosus sodium channel protein 0.0455 0.1602 0.1602
Echinococcus granulosus calcium activated potassium channel 0.0045 0.0063 0.0063
Onchocerca volvulus 0.0038 0.0036 0.0208
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.0024
Trypanosoma cruzi 14-3-3 protein 1, putative 0.0034 0.0022 0.0222
Loa Loa (eye worm) voltage-gated potassium channel 0.0043 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0308 0.1858
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1357 0.4991 0.6832
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0158 0.031
Schistosoma mansoni hypothetical protein 0.0031 0.0009 0.0019
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0025 0.0025
Toxoplasma gondii PAN domain-containing protein 0.0172 0.054 0.0544
Brugia malayi Nuclear hormone receptor family member nhr-19 0.008 0.0194 0.0266
Echinococcus granulosus 14-3-3 protein gamma 0.0034 0.0022 0.0022
Brugia malayi ORL1-like opioid receptor 0.0144 0.0436 0.0596
Loa Loa (eye worm) voltage-gated potassium channel 0.0043 0.0057 0.0078
Schistosoma mansoni glutamate receptor NMDA 0.0259 0.0866 0.1699
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus granulosus allatostatin A receptor 0.028 0.0946 0.0946
Plasmodium falciparum thioredoxin reductase 0.0047 0.0072 0.3975
Echinococcus granulosus thyroid hormone receptor alpha 0.0038 0.0036 0.0036
Onchocerca volvulus 0.007 0.0158 0.1265
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0185 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0072
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0151 0.0461 0.0461
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Brugia malayi RNA, U transporter 1 0.008 0.0195 0.0267
Echinococcus granulosus tm gpcr rhodopsin 0.0645 0.2319 0.2319
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0078 0.0106
Schistosoma mansoni hypothetical protein 0.0441 0.1552 0.3046
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0158 0.0929
Toxoplasma gondii microneme protein, putative 0.0172 0.054 0.0544
Trypanosoma brucei hypothetical protein 0.011 0.0308 0.6676
Schistosoma mansoni hypothetical protein 0.0144 0.0436 0.0855
Echinococcus granulosus cpg binding protein 0.0029 0.0005 0.0004
Schistosoma mansoni biogenic amine receptor 0.0144 0.0436 0.0855
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0079 0.019 1
Chlamydia trachomatis glutamine binding protein 0.0079 0.019 1
Echinococcus granulosus 14-3-3 protein 0.0034 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-49 0.008 0.0194 0.0266
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0256 0.0256
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis conserved hypothetical protein 0.0043 0.0057 0.0057
Echinococcus multilocularis deoxyribonuclease ii 0.0073 0.0167 0.0167
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.008 0.0194 0.0266
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Brugia malayi nuclear receptor NHR-88 0.0038 0.0036 0.0049
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0036 0.044
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0339 0.1169 0.2295
Schistosoma mansoni coup transcription factor 0.008 0.0194 0.0381
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0158 0.0929
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.008 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Loa Loa (eye worm) hypothetical protein 0.0058 0.0112 0.0154
Echinococcus granulosus ecdysone induced protein 78C 0.008 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0216
Onchocerca volvulus 0.0144 0.0436 0.3662
Onchocerca volvulus 0.0172 0.054 0.4566
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0043 0.0057 0.0985
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0041 1
Onchocerca volvulus 0.0144 0.0436 0.3662
Schistosoma mansoni hypothetical protein 0.0077 0.0182 0.0357
Onchocerca volvulus 0.008 0.0195 0.1585
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0043 0.0057 0.1228
Trypanosoma brucei trypanothione reductase 0.0047 0.0072 0.1566
Echinococcus multilocularis neuropeptide Y receptor 0.0144 0.0436 0.0435
Schistosoma mansoni alpha-glucosidase 0.0286 0.0969 0.1901
Echinococcus granulosus neuropeptide Y receptor 0.0144 0.0436 0.0435
Echinococcus granulosus enteropeptidase 0.008 0.0195 0.0195
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0171 0.0172
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0057 0.0057
Onchocerca volvulus 0.0192 0.0616 0.5221
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0036 0.0516
Schistosoma mansoni hypothetical protein 0.0077 0.0182 0.0357
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0195 0.0383
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.0308 0.6676
Echinococcus multilocularis ecdysone induced protein 78C 0.008 0.0194 0.0194
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0034 0.0022 0.0277
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0055 0.0055
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0057 0.0057
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0171 0.0998
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0000063435 0.0000063883
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0068 0.0068
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0057 0.0111
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Onchocerca volvulus 0.0144 0.0436 0.3662
Brugia malayi Deoxyribonuclease II family protein 0.0073 0.0167 0.0229
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0158 0.1952
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Echinococcus multilocularis two pore calcium channel protein 2 0.0043 0.0057 0.0057
Toxoplasma gondii transporter, cation channel family protein 0.0151 0.0461 0.0464
Brugia malayi nuclear hormone receptor family member nhr-6 0.0038 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.1973 0.7306 1
Loa Loa (eye worm) brahma associated protein 0.0077 0.0182 0.0249
Onchocerca volvulus 0.0172 0.054 0.4566
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0158 0.0216
Echinococcus granulosus Mastin 0.008 0.0195 0.0195
Brugia malayi G protein-coupled receptor F59B2.13 0.0144 0.0436 0.0596
Brugia malayi RE15519p 0.0144 0.0436 0.0596
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0266
Brugia malayi G-protein coupled receptor 0.0144 0.0436 0.0596
Brugia malayi hypothetical protein 0.0038 0.0036 0.0049
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0182 1
Schistosoma mansoni voltage-gated cation channel 0.0151 0.0461 0.0905
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0043 0.0057 0.0078
Toxoplasma gondii hypothetical protein 0.0108 0.0299 0.0301
Loa Loa (eye worm) hypothetical protein 0.0074 0.0174 0.0238
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0055 0.301
Mycobacterium ulcerans hypothetical protein 0.007 0.0158 0.7975
Schistosoma mansoni myosin xvIII 0.0144 0.0436 0.0855
Loa Loa (eye worm) adenylyl cyclase 3 0.0137 0.041 0.0561
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0144 0.0436 0.0435
Plasmodium falciparum glutathione reductase 0.0047 0.0072 0.3975
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0144 0.0436 0.0435
Echinococcus granulosus somatostatin receptor 0.0144 0.0436 0.0435
Schistosoma mansoni neuropeptide receptor 0.0144 0.0436 0.0855
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0036 0.0516
Echinococcus granulosus 14-3-3 protein 0.0034 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0078
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0028 0.01
Toxoplasma gondii PAN domain-containing protein 0.2671 0.993 1
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.0009 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.0194 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-41 0.008 0.0194 0.0266
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0151 0.0461 0.0631
Echinococcus multilocularis enteropeptidase 0.008 0.0195 0.0195
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.045 0.0616
Loa Loa (eye worm) hypothetical protein 0.0915 0.3333 0.4562
Schistosoma mansoni Tr4/Tr2 (homologue) 0.008 0.0194 0.0381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.008 0.0194 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0436 0.0855
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0028 0.0029
Echinococcus granulosus shaker cognate 0.0043 0.0057 0.0057
Onchocerca volvulus 0.0172 0.054 0.4566
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.0699 0.0957
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.008 0.0194 0.0381
Loa Loa (eye worm) glutamate receptor 1 0.0031 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0049
Mycobacterium ulcerans beta-lactamase 0.007 0.0158 0.7975
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0144 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0144 0.0436 0.0596
Onchocerca volvulus 0.0144 0.0436 0.3662
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0028 0.0028
Loa Loa (eye worm) apoptosis regulator protein 0.0215 0.0701 0.096
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0436 0.0855
Brugia malayi hypothetical protein 0.0144 0.0436 0.0596
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0057 0.0111
Brugia malayi RNA binding protein 0.0063 0.0129 0.0177
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0057 0.0111
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0057 0.0057
Schistosoma mansoni voltage-dependent calcium channel 0.0043 0.0057 0.0111
Echinococcus granulosus voltage dependent calcium channel 0.0151 0.0461 0.0461
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0158 0.0929
Toxoplasma gondii hypothetical protein 0.0172 0.054 0.0544
Leishmania major 14-3-3 protein-like protein 0.0034 0.0022 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0256 0.0256
Brugia malayi Cytochrome P450 family protein 0.0049 0.0078 0.0106
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0158 0.3428
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0031
Echinococcus multilocularis thyroid hormone receptor alpha 0.008 0.0194 0.0194
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0057 0.0057
Echinococcus granulosus transmembrane protease serine 3 0.008 0.0195 0.0195

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 4.8 nM Agonist activity at rat androgen receptor expressed in mouse skeletal muscle C2C12 cells assessed as transcriptional activation after 24 hrs by androgen-specific response element driven luciferase reporter gene assay ChEMBL. 19351168
Ki (binding) = 0.8 nM Displacement of [3H[DHT from androgen receptor endogenously expressed in human MDA-MB-453 cells ChEMBL. 19351168

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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