Detailed information for compound 1036443

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 397.898 | Formula: C22H24ClN3O2
  • H donors: 1 H acceptors: 2 LogP: 3.35 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNCc1nccn1CC1OC(=O)C(C1)(c1ccccc1)c1ccccc1.Cl
  • InChi: 1S/C22H23N3O2.ClH/c1-23-15-20-24-12-13-25(20)16-19-14-22(21(26)27-19,17-8-4-2-5-9-17)18-10-6-3-7-11-18;/h2-13,19,23H,14-16H2,1H3;1H
  • InChiKey: KIGLPWCJKOUEOU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0025 0.0107
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0017 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0017 0.0052
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0196 0.0383 0.0382
Onchocerca volvulus 0.0205 0.0405 0.1146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Entamoeba histolytica cysteine proteinase, putative 0.0144 0.0259 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0074 0.0094 0.3584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni sodium/chloride dependent transporter 0.0205 0.0405 0.079
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0015 0.0035
Leishmania major GTP-binding protein, putative 0.0045 0.0025 0.0107
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0025 0.0068
Echinococcus granulosus importin subunit beta 1 0.0061 0.0063 0.0122
Schistosoma mansoni importin beta-1 0.0061 0.0063 0.0122
Brugia malayi TAR-binding protein 0.0321 0.068 0.2276
Plasmodium falciparum phosphatase, putative 0.0051 0.0039 0.07
Toxoplasma gondii ABC1 family protein 0.0185 0.0357 0.6732
Echinococcus multilocularis phd:f box containing protein 0.0039 0.0011 0.001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0175 0.0617
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0017 0.004
Echinococcus granulosus tumor protein p63 0.1341 0.3102 0.6058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0039 0.0206
Schistosoma mansoni tar DNA-binding protein 0.0321 0.068 0.1327
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0015 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0094 0.3584
Schistosoma mansoni cathepsin F (C01 family) 0.0144 0.0259 0.0504
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0234 0.0474 0.0924
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0025 0.0531
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.001 0.033
Echinococcus granulosus peregrin 0.0122 0.0208 0.0405
Plasmodium falciparum amino acid transporter, putative 0.0205 0.0405 1
Mycobacterium leprae Probable imidazole glycerol-phosphate dehydratase HisB 0.0606 0.1357 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0017 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Brugia malayi glutaminase DH11.1 0.0273 0.0566 0.1891
Leishmania major DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0025 0.0341
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Schistosoma mansoni cathepsin s 0.0048 0.0031 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0017 0.004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.7675
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0015 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0096 0.0146 0.0402
Schistosoma mansoni smad 0.0066 0.0075 0.0144
Loa Loa (eye worm) hypothetical protein 0.0236 0.0478 0.1587
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0015 0.0522
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0114 0.0189 0.0368
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0025 0.0107
Echinococcus granulosus lysosomal alpha glucosidase 0.0336 0.0716 0.1396
Leishmania major cathepsin L-like protease 0.0144 0.0259 0.1752
Loa Loa (eye worm) hypothetical protein 0.0188 0.0363 0.1202
Loa Loa (eye worm) hypothetical protein 0.0039 0.0011 0.0023
Schistosoma mansoni cathepsin F (C01 family) 0.0144 0.0259 0.0504
Trypanosoma cruzi polynucleotide kinase 3'-phosphatase, putative 0.0051 0.0039 0.0206
Echinococcus granulosus cathepsin L cysteine protease 0.0074 0.0094 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0095 0.0597
Plasmodium falciparum cysteine proteinase falcipain 1 0.0074 0.0094 0.2086
Trypanosoma brucei polynucleotide kinase 3'-phosphatase, putative 0.0051 0.0039 0.0206
Brugia malayi RNA binding protein 0.0321 0.068 0.2276
Echinococcus granulosus cathepsin l1 0.0096 0.0146 0.0284
Plasmodium falciparum importin beta, putative 0.0061 0.0063 0.1317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Loa Loa (eye worm) jmjC domain-containing protein 0.0155 0.0286 0.0943
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.004 0.0013 0.0058
Trichomonas vaginalis ran, putative 0.0045 0.0025 0.0045
Schistosoma mansoni hypothetical protein 0.07 0.1581 0.3085
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0196 0.0383 0.0746
Schistosoma mansoni microtubule-associated protein tau 0.2191 0.512 1
Trichomonas vaginalis D-aminoacylase, putative 0.0185 0.0357 0.1021
Plasmodium falciparum cysteine proteinase falcipain 3 0.0144 0.0259 0.6291
Mycobacterium ulcerans beta-lactamase 0.0185 0.0357 0.1229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0639 0.1434 1
Echinococcus granulosus muscleblind protein 0.0674 0.1518 0.2963
Echinococcus granulosus lysine specific demethylase 5A 0.0155 0.0286 0.0556
Mycobacterium tuberculosis Probable imidazole glycerol-phosphate dehydratase HisB 0.1229 0.2835 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Trypanosoma brucei PAB1-binding protein , putative 0.0102 0.0159 0.105
Trypanosoma cruzi cruzipain precursor, putative 0.0548 0.1219 0.849
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0026 0.0049
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0039 0.0011 0.0013
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0205 0.0405 0.079
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0015 0.0018
Echinococcus granulosus mixed lineage leukemia protein mll 0.0037 0.0005 0.0008
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0095 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0144 0.0259 0.0734
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0109 0.0178 0.1179
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0095 0.025
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.0095 0.0597
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0196 0.0383 0.0746
Schistosoma mansoni tar DNA-binding protein 0.0321 0.068 0.1327
Echinococcus granulosus dna polymerase eta 0.0041 0.0015 0.0026
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.0095 0.0183
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0204 0.0718
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0044 0.0023 0.0021
Echinococcus granulosus ubiquitin specific protease 41 0.0114 0.0189 0.0368
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0188 0.0363 0.0362
Echinococcus multilocularis bifunctional polynucleotide 0.0051 0.0039 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0047 0.003 0.0474
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0639 0.1434 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0205 0.0405 0.079
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0188 0.0363 0.0707
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.003 0.0107
Echinococcus multilocularis ubiquitin specific protease 41 0.0114 0.0189 0.0188
Schistosoma mansoni aldehyde dehydrogenase 0.0256 0.0525 0.1024
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0205 0.0405 0.0404
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0478 0.0931
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0063 0.0377
Mycobacterium tuberculosis Probable lipase LipE 0.0185 0.0357 0.1258
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0234 0.0474 0.0924
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0017 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0185 0.0357 0.1181
Brugia malayi Thioredoxin reductase 0.0047 0.003 0.0098
Echinococcus multilocularis GPCR, family 2 0.0196 0.0383 0.0382
Echinococcus granulosus JmjC domain containing protein 4 0.0039 0.0011 0.002
Loa Loa (eye worm) RNA binding protein 0.0321 0.068 0.2267
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0094 0.3584
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.0357 0.2437
Brugia malayi hypothetical protein 0.0236 0.0478 0.1597
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0017 0.003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0196 0.0383 0.0382
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0017 0.0052
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0144 0.0259 0.0854
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0302 0.0635 0.4393
Onchocerca volvulus 0.0144 0.0259 0.0715
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.003 0.0029
Loa Loa (eye worm) MH2 domain-containing protein 0.0066 0.0075 0.0236
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0074 0.0094 0.059
Toxoplasma gondii cathepsin CPL 0.0144 0.0259 0.4841
Onchocerca volvulus 0.0144 0.0259 0.0715
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0234 0.0474 0.0924
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Schistosoma mansoni hypothetical protein 0.0655 0.1473 0.2874
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0015 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0063 0.0062
Mycobacterium tuberculosis Conserved hypothetical protein 0.0336 0.0717 0.2527
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0017 0.0016
Brugia malayi Cytochrome P450 family protein 0.0081 0.0111 0.0367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0017 0.0016
Mycobacterium leprae conserved hypothetical protein 0.0185 0.0357 0.263
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0015 0.0013
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.001 0.5
Schistosoma mansoni phosphatidylserine receptor 0.0039 0.0011 0.002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0175 0.0617
Plasmodium falciparum glutathione reductase 0.0047 0.003 0.0482
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0094 0.059
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0185 0.0357 0.1258
Echinococcus multilocularis cathepsin L 0.0074 0.0094 0.0093
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0095 0.0302
Loa Loa (eye worm) Smad1 0.0066 0.0075 0.0236
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0063 0.1041
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.1354
Echinococcus multilocularis cysteine protease 0.0144 0.0259 0.0258
Brugia malayi Pre-SET motif family protein 0.0188 0.0363 0.1213
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0185 0.0357 0.1258
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0025 0.0107
Echinococcus multilocularis beta LACTamase domain containing family member 0.0185 0.0357 0.0356
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0017 0.0052
Loa Loa (eye worm) TAR-binding protein 0.0321 0.068 0.2267
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0013 0.0021
Toxoplasma gondii hypothetical protein 0.0205 0.0405 0.7675
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0094 0.059
Echinococcus multilocularis cpg binding protein 0.0128 0.0221 0.022
Loa Loa (eye worm) serotonin transporter b 0.121 0.2791 0.9345
Schistosoma mansoni cathepsin F (C01 family) 0.0096 0.0146 0.0284
Echinococcus multilocularis sodium and chloride dependent glycine 0.0205 0.0405 0.0404
Leishmania major cathepsin L-like protease 0.0548 0.1219 0.849
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0234 0.0474 0.1585
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0094 0.031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0185 0.0357 0.0695
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0017 0.0052
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0114 0.0189 0.0188
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0114 0.0189 0.7288
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0017 0.003
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Echinococcus granulosus GPCR family 2 0.0196 0.0383 0.0746
Brugia malayi F/Y-rich N-terminus family protein 0.0084 0.0116 0.0386
Echinococcus granulosus tar DNA binding protein 0.0321 0.068 0.1327
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.1344
Plasmodium vivax importin-beta 2, putative 0.0061 0.0063 0.1317
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0005 0.0008
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0039 0.0011 0.0035
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0017 0.003
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Loa Loa (eye worm) hypothetical protein 0.121 0.2791 0.9345
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.0095 0.025
Brugia malayi PHD-finger family protein 0.0122 0.0208 0.0694
Echinococcus granulosus PHD finger protein rhinoceros 0.0122 0.0208 0.0405
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0175 0.0617
Plasmodium falciparum transporter, putative 0.0205 0.0405 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0205 0.0405 0.5
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.003 0.0482
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0017 0.003
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0256 0.0525 0.3619
Echinococcus multilocularis muscleblind protein 1 0.0674 0.1518 0.1517
Brugia malayi Cathepsin L-like precursor 0.0048 0.0031 0.0099
Brugia malayi RNA recognition motif domain containing protein 0.0321 0.068 0.2276
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0263 0.0542 0.1057
Trichomonas vaginalis esterase, putative 0.0185 0.0357 0.1021
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0017 0.0052
Echinococcus granulosus neuropeptide receptor A26 0.0484 0.1067 0.2082
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0017 0.003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0011 0.0013
Trypanosoma cruzi cysteine protease, putative 0.0074 0.0094 0.059
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0178 0.0341 0.0663
Brugia malayi Calcitonin receptor-like protein seb-1 0.0619 0.1389 0.4649
Echinococcus granulosus geminin 0.07 0.1581 0.3085
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0256 0.0525 0.1024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0114 0.0189 0.0528
Mycobacterium tuberculosis Probable lipase LipD 0.0185 0.0357 0.1258
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0036 0.0077
Trypanosoma brucei glucosidase, putative 0.0075 0.0095 0.0597
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Loa Loa (eye worm) hypothetical protein 0.0619 0.1389 0.4643
Echinococcus granulosus dna polymerase kappa 0.0041 0.0015 0.0026
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0114 0.0189 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0189 0.0528
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0144 0.0259 0.0854
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0074 0.0094 0.0181
Brugia malayi jmjC domain containing protein 0.0401 0.0869 0.2908
Plasmodium vivax vivapain-2 0.0144 0.0259 0.6291
Entamoeba histolytica cysteine proteinase, putative 0.0144 0.0259 1
Mycobacterium tuberculosis Conserved protein 0.0185 0.0357 0.1258
Loa Loa (eye worm) hypothetical protein 0.0122 0.0208 0.0683
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0048 0.0031 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0017 0.0052
Brugia malayi Cathepsin L-like precursor 0.0144 0.0259 0.0865
Brugia malayi Inositol-1 0.0039 0.001 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0094 0.3584
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0205 0.0405 0.079
Trichomonas vaginalis penicillin-binding protein, putative 0.0185 0.0357 0.1021
Brugia malayi Cathepsin L-like precursor 0.0096 0.0146 0.0487
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0039 0.0011 0.0035
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0144 0.0259 0.0258
Schistosoma mansoni hypothetical protein 0.0196 0.0383 0.0746
Onchocerca volvulus 0.0205 0.0405 0.1146
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0095 0.025
Leishmania major cathepsin L-like protease 0.0144 0.0259 0.1752
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0185 0.0357 0.0695
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.009 0.0131 0.0851
Plasmodium vivax glutathione reductase, putative 0.0047 0.003 0.0482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0096 0.0146 0.0402
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0074 0.0094 0.0181
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0114 0.0189 0.1261
Loa Loa (eye worm) hypothetical protein 0.0185 0.0357 0.1181
Loa Loa (eye worm) hypothetical protein 0.0102 0.0159 0.0519
Onchocerca volvulus 0.0205 0.0405 0.1146
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.003 0.0057
Leishmania major cathepsin L-like protease 0.0144 0.0259 0.1752
Onchocerca volvulus 0.0048 0.0032 0.0045
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0114 0.0189 0.0368
Mycobacterium ulcerans aldehyde dehydrogenase 0.0256 0.0525 0.1825
Loa Loa (eye worm) hypothetical protein 0.0185 0.0357 0.1181
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0144 0.0259 0.0258
Leishmania major importin beta-1 subunit, putative 0.005 0.0036 0.0184
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0205 0.0405 0.079
Echinococcus multilocularis dnaJ subfamily B 0.0869 0.1982 0.1981
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.0159 0.3752
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0015 0.0026
Trypanosoma cruzi cysteine proteinase, putative 0.0074 0.0094 0.059
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.7675
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0015 0.0015
Brugia malayi jmjC domain containing protein 0.0039 0.0011 0.0035
Brugia malayi hypothetical protein 0.0205 0.0405 0.1354
Brugia malayi PHD-finger family protein 0.0047 0.0029 0.0093
Echinococcus granulosus cathepsin l1 0.0144 0.0259 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0017 0.0052
Leishmania major cathepsin L-like protease 0.0144 0.0259 0.1752
Brugia malayi hypothetical protein 0.0102 0.0159 0.053
Onchocerca volvulus 0.0196 0.0384 0.1082
Mycobacterium tuberculosis Probable esterase LipL 0.0185 0.0357 0.1258
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Leishmania major hypothetical protein, conserved 0.0102 0.0159 0.105
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0017 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0321 0.068 0.1327
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0114 0.0189 0.9021
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0005 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0017 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0015 0.0045
Onchocerca volvulus Cathepsin L homolog 0.0144 0.0259 0.0715
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0114 0.0189 0.0188
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0114 0.0189 0.0528
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0017 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Brugia malayi steroid hormone receptor 0.0042 0.0017 0.0052
Schistosoma mansoni ran 0.0045 0.0025 0.0046
Entamoeba histolytica cysteine protease, putative 0.0144 0.0259 1
Echinococcus granulosus bifunctional polynucleotide 0.0051 0.0039 0.0074
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0205 0.0405 0.079
Trypanosoma brucei DNA polymerase beta thumb, putative 0.009 0.0131 0.0851
Plasmodium vivax amine transporter, putative 0.0205 0.0405 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0047 0.003 0.0474
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0017 0.0052
Schistosoma mansoni hypothetical protein 0.0869 0.1982 0.3869
Schistosoma mansoni hypothetical protein 0.0196 0.0383 0.0746
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0321 0.068 0.2267
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0017 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0017 0.004
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0256 0.0525 0.0524
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0175 0.0617
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Echinococcus multilocularis cathepsin L cysteine protease 0.0144 0.0259 0.0258
Plasmodium vivax ataxin-2 like protein, putative 0.0102 0.0159 0.3752
Brugia malayi MH1 domain containing protein 0.0037 0.0005 0.0012
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0048 0.0031 0.0099
Giardia lamblia PHD finger protein 15 0.0122 0.0208 1
Brugia malayi Cathepsin L-like precursor 0.0144 0.0259 0.0865
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0015 0.0035
Onchocerca volvulus 0.0144 0.0259 0.0715
Plasmodium vivax hypothetical protein, conserved 0.0185 0.0357 0.8766
Brugia malayi Cathepsin L-like precursor 0.0096 0.0146 0.0487
Brugia malayi Smad1 0.0066 0.0075 0.0247
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0114 0.0189 0.063
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0063 0.0377
Entamoeba histolytica cysteine proteinase, putative 0.0096 0.0146 0.5626
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0015 0.0035
Mycobacterium ulcerans imidazoleglycerol-phosphate dehydratase 0.1229 0.2835 1
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.003 0.0146
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0234 0.0474 0.0924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.0095 0.165
Schistosoma mansoni jumonji/arid domain-containing protein 0.0155 0.0286 0.0556
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0017 0.003
Echinococcus granulosus sodium and chloride dependent glycine 0.0205 0.0405 0.079
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0015 0.0026
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0036 0.0077
Echinococcus multilocularis Smad4 0.0066 0.0075 0.0074
Trypanosoma cruzi cysteine peptidase, putative 0.0048 0.0031 0.0147
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0302 0.0635 0.4393
Loa Loa (eye worm) latrophilin receptor protein 2 0.0196 0.0383 0.127
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0025 0.008
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0095 0.025
Loa Loa (eye worm) hypothetical protein 0.0196 0.0384 0.1272
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0234 0.0474 0.0924
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0026 0.0025
Mycobacterium tuberculosis Conserved protein 0.0185 0.0357 0.1258
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0017 0.003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.121 0.2791 0.5449
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.003 0.0087
Loa Loa (eye worm) hypothetical protein 0.0674 0.1518 0.5076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni hypothetical protein 0.0046 0.0026 0.0049
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0015 0.0015
Onchocerca volvulus Cathepsin L homolog 0.0144 0.0259 0.0715
Loa Loa (eye worm) hypothetical protein 0.0051 0.0039 0.0115
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344
Schistosoma mansoni hypothetical protein 0.004 0.0013 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.1354
Brugia malayi beta-lactamase 0.0185 0.0357 0.1192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0017 0.0016
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0204 0.0718
Brugia malayi Cathepsin L-like precursor 0.0144 0.0259 0.0865
Echinococcus granulosus beta LACTamase domain containing family member 0.0185 0.0357 0.0695
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0205 0.0405 0.079
Echinococcus multilocularis lysine specific demethylase 6a 0.0039 0.0011 0.001
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0017 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Schistosoma mansoni hypothetical protein 0.0423 0.0923 0.1802
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.0095 0.025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0234 0.0474 0.1575
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.0111 0.0355
Loa Loa (eye worm) hypothetical protein 0.0048 0.0031 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Leishmania major hypothetical protein, conserved 0.0185 0.0357 0.2437
Loa Loa (eye worm) hypothetical protein 0.0185 0.0357 0.1181
Loa Loa (eye worm) MH2 domain-containing protein 0.0972 0.2226 0.745
Echinococcus granulosus lysine specific demethylase 6a 0.0039 0.0011 0.002
Leishmania major hypothetical protein, conserved 0.0039 0.0011 0.0013
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0017 0.0016
Schistosoma mansoni alpha glucosidase 0.0075 0.0095 0.0183
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0114 0.0189 0.1261
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0095 0.025
Onchocerca volvulus 0.0144 0.0259 0.0715
Echinococcus multilocularis snurportin 1 0.0655 0.1473 0.1472
Echinococcus granulosus smad 0.0066 0.0075 0.0144
Loa Loa (eye worm) hypothetical protein 0.021 0.0416 0.1379
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344
Loa Loa (eye worm) beta-lactamase 0.0185 0.0357 0.1181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Loa Loa (eye worm) glutathione reductase 0.0047 0.003 0.0087
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.7675
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.0131 0.0851
Echinococcus granulosus histone lysine methyltransferase setb 0.0188 0.0363 0.0707
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0017 0.003
Echinococcus granulosus cpg binding protein 0.0128 0.0221 0.0429
Trypanosoma cruzi cysteine peptidase, putative 0.0548 0.1219 0.849
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0185 0.0357 0.1181
Brugia malayi beta-lactamase family protein 0.0185 0.0357 0.1192
Leishmania major DNA polymerase eta, putative 0.0041 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0122 0.0208 0.3851
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0619 0.1389 0.4649
Echinococcus granulosus microtubule associated protein 2 0.2191 0.512 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.05 0.1106 0.7697
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0025 0.0341
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.0159 0.3752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0094 0.0247
Echinococcus multilocularis jumonji domain containing protein 0.017 0.0322 0.0321
Loa Loa (eye worm) hypothetical protein 0.0185 0.0357 0.1181
Plasmodium vivax SET domain protein, putative 0.0188 0.0363 0.8928
Schistosoma mansoni sodium-dependent amino acid transporter 0.0205 0.0405 0.079
Brugia malayi Cathepsin L-like precursor 0.0144 0.0259 0.0865
Onchocerca volvulus 0.121 0.2791 0.8177
Trichomonas vaginalis penicillin-binding protein, putative 0.0185 0.0357 0.1021
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.0159 0.105
Echinococcus granulosus Smad4 0.0066 0.0075 0.0144
Loa Loa (eye worm) cysteine protease 0.0144 0.0259 0.0854
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0017 0.0052
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0175 0.1289
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0017 0.003
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0017 0.003
Schistosoma mansoni inositol monophosphatase 0.0039 0.001 0.0017
Brugia malayi beta-lactamase family protein 0.0185 0.0357 0.1192
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0639 0.1434 1
Loa Loa (eye worm) norepinephrine transporter 0.121 0.2791 0.9345
Brugia malayi MH2 domain containing protein 0.0066 0.0075 0.0247
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0095 0.025
Brugia malayi jmjC domain containing protein 0.0039 0.0011 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Mycobacterium ulcerans lipase LipD 0.0185 0.0357 0.1229
Plasmodium vivax vivapain-1 0.0074 0.0094 0.2086
Schistosoma mansoni alpha-glucosidase 0.0289 0.0604 0.1179
Schistosoma mansoni sodium/chloride dependent transporter 0.121 0.2791 0.5449
Echinococcus multilocularis cysteine protease 0.0144 0.0259 0.0258
Plasmodium falciparum phd finger protein, putative 0.0122 0.0208 0.4995
Leishmania major cysteine peptidase A (CPA) 0.0144 0.0259 0.1752
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Plasmodium vivax bifunctional polynucleotide phosphatase/kinase, putative 0.0051 0.0039 0.07
Schistosoma mansoni tar DNA-binding protein 0.0321 0.068 0.1327
Mycobacterium ulcerans aldehyde dehydrogenase 0.0256 0.0525 0.1825
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0066 0.0075 0.0144
Onchocerca volvulus 0.0188 0.0363 0.1021
Loa Loa (eye worm) MH1 domain-containing protein 0.0066 0.0075 0.0236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni hypothetical protein 0.0196 0.0383 0.0746
Loa Loa (eye worm) hypothetical protein 0.0047 0.0029 0.0082
Echinococcus granulosus mothers against decapentaplegic 5 0.0066 0.0075 0.0144
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0017 0.003
Entamoeba histolytica polynucleotide kinase-3-phosphatase, putative 0.0051 0.0039 0.1468
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0039 0.0206
Loa Loa (eye worm) hypothetical protein 0.0041 0.0015 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Brugia malayi hypothetical protein 0.0066 0.0074 0.0243
Brugia malayi DNA 3'-phosphatase family protein 0.0051 0.0039 0.0127
Schistosoma mansoni jumonji/arid domain-containing protein 0.0155 0.0286 0.0556
Echinococcus granulosus jumonji domain containing protein 0.017 0.0322 0.0627
Onchocerca volvulus 0.0121 0.0204 0.0553
Echinococcus multilocularis dna polymerase eta 0.0041 0.0015 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni inositol monophosphatase 0.0039 0.001 0.0017
Schistosoma mansoni coup transcription factor 0.0042 0.0017 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Loa Loa (eye worm) hypothetical protein 0.0048 0.0031 0.0087
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0204 0.0718
Echinococcus multilocularis PHD finger protein rhinoceros 0.0122 0.0208 0.0207
Echinococcus multilocularis geminin 0.07 0.1581 0.158
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.0159 0.105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Plasmodium falciparum bifunctional polynucleotide phosphatase/kinase 0.0051 0.0039 0.07
Echinococcus granulosus snurportin 1 0.0655 0.1473 0.2874
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0363 0.0707
Entamoeba histolytica Ran family GTPase 0.0045 0.0025 0.092
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0094 0.031
Trypanosoma cruzi cysteine proteinase, putative 0.0074 0.0094 0.059
Schistosoma mansoni aldehyde dehydrogenase 0.0256 0.0525 0.1024
Loa Loa (eye worm) inositol-1 0.0039 0.001 0.0017
Brugia malayi Glycosyl hydrolases family 31 protein 0.0336 0.0716 0.2394
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.0716 0.0715
Mycobacterium ulcerans glutaminase 0.0273 0.0566 0.1968
Leishmania major cathepsin L-like protease 0.0548 0.1219 0.849
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0114 0.0189 0.0368
Leishmania major trypanothione reductase 0.0047 0.003 0.0146
Toxoplasma gondii thioredoxin reductase 0.0047 0.003 0.0404
Echinococcus multilocularis smad 0.0066 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Echinococcus multilocularis peregrin 0.0122 0.0208 0.0207
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0204 0.1501
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0017 0.004
Leishmania major mitochondrial DNA polymerase beta 0.0639 0.1434 1
Schistosoma mansoni cpg binding protein 0.0128 0.0221 0.0429
Schistosoma mansoni polynucleotide kinase-3'-phosphatase 0.0051 0.0039 0.0074
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0025 0.0295
Schistosoma mansoni jumonji domain containing protein 0.0039 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0114 0.0189 0.0619
Trichomonas vaginalis importin beta-1, putative 0.005 0.0036 0.0077
Echinococcus multilocularis microtubule associated protein 2 0.2191 0.512 0.512
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.001 0.0009
Echinococcus granulosus cysteine protease 0.0074 0.0094 0.0181
Echinococcus granulosus neuropeptide s receptor 0.0484 0.1067 0.2082
Echinococcus multilocularis sodium and chloride dependent glycine 0.0205 0.0405 0.0404
Mycobacterium tuberculosis Probable reductase 0.0108 0.0175 0.0617
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0017 0.004
Loa Loa (eye worm) PHD-finger family protein 0.0122 0.0208 0.0683
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.1344
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0122 0.0208 0.0405
Trichomonas vaginalis D-aminoacylase, putative 0.0185 0.0357 0.1021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Brugia malayi Cathepsin L-like precursor 0.0144 0.0259 0.0865
Brugia malayi jmjC domain containing protein 0.0155 0.0286 0.0953
Loa Loa (eye worm) glutaminase 0.0273 0.0566 0.1882
Mycobacterium leprae Probable lipase LipE 0.0185 0.0357 0.263
Trypanosoma brucei trypanothione reductase 0.0047 0.003 0.0146
Plasmodium vivax unspecified product 0.0074 0.0094 0.2086
Echinococcus granulosus serotonin transporter 0.121 0.2791 0.5449
Brugia malayi RNA, U transporter 1 0.0174 0.0332 0.1108
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0015 0.0026
Onchocerca volvulus 0.0185 0.0357 0.1003
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0094 0.3584
Schistosoma mansoni cellular tumor antigen P53 0.0196 0.0384 0.0748
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0095 0.025
Brugia malayi nuclear receptor NHR-88 0.0042 0.0017 0.0052
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0478 0.0477
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.0036 0.0184
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0188 0.0363 0.0362
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0017 0.003
Loa Loa (eye worm) transcription factor SMAD2 0.0972 0.2226 0.745
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0017 0.0052
Echinococcus granulosus cathepsin L cysteine proteinase 0.0144 0.0259 0.0504
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Brugia malayi Pre-SET motif family protein 0.1292 0.2986 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0363 0.0707
Loa Loa (eye worm) hypothetical protein 0.0039 0.0011 0.0023
Mycobacterium ulcerans hypothetical protein 0.0185 0.0357 0.1229
Trypanosoma cruzi polynucleotide kinase 3'-phosphatase, putative 0.0051 0.0039 0.0206
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Loa Loa (eye worm) glutaminase 2 0.0273 0.0566 0.1882
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0066 0.0075 0.0074
Toxoplasma gondii hypothetical protein 0.0205 0.0405 0.7675
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0205 0.0405 0.079
Onchocerca volvulus 0.0185 0.0357 0.1003
Schistosoma mansoni cpg binding protein 0.0128 0.0221 0.0429
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.0095 0.0094
Leishmania major cathepsin L-like protease 0.0144 0.0259 0.1752
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Schistosoma mansoni protein phosphatase 2C 0.0039 0.0011 0.002
Brugia malayi jmjC domain containing protein 0.0039 0.0011 0.0035
Mycobacterium tuberculosis Probable hydrolase 0.0185 0.0357 0.1258
Brugia malayi ecdysteroid receptor 0.0042 0.0017 0.0052
Onchocerca volvulus 0.0194 0.0379 0.1069
Loa Loa (eye worm) hypothetical protein 0.0674 0.1518 0.5076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Trypanosoma cruzi major cysteine proteinase, putative 0.0431 0.0941 0.6535
Schistosoma mansoni survival motor neuron protein 0.0048 0.0032 0.006
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0205 0.0405 0.1354
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0095 0.025
Schistosoma mansoni tar DNA-binding protein 0.0321 0.068 0.1327
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0017 0.003
Loa Loa (eye worm) hypothetical protein 0.121 0.2791 0.9345
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1292 0.2986 1
Mycobacterium ulcerans hypothetical protein 0.0336 0.0717 0.2502
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0302 0.0635 0.4393
Echinococcus multilocularis muscleblind protein 0.0674 0.1518 0.1517
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0234 0.0474 0.0473
Schistosoma mansoni cpg binding protein 0.0121 0.0204 0.0397
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Toxoplasma gondii aldehyde dehydrogenase 0.0256 0.0525 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0017 0.004
Entamoeba histolytica hypothetical protein 0.005 0.0036 0.1343
Onchocerca volvulus 0.0185 0.0357 0.1003
Brugia malayi Muscleblind-like protein 0.0674 0.1518 0.5082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0363 0.0707
Onchocerca volvulus 0.0144 0.0259 0.0715
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0205 0.0405 0.0404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0074 0.0094 0.0181
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0037 0.0005 0.0004
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0401 0.0869 0.1696
Loa Loa (eye worm) solute carrier family 6 member 4 0.121 0.2791 0.9345
Echinococcus multilocularis neuropeptide s receptor 0.0484 0.1067 0.1066
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0144 0.0259 0.6291
Loa Loa (eye worm) ctsf protein 0.0144 0.0259 0.0854
Echinococcus granulosus jumonji domain containing 1A 0.0039 0.0011 0.002
Echinococcus multilocularis neuropeptide receptor A26 0.0484 0.1067 0.1066
Loa Loa (eye worm) hypothetical protein 0.121 0.2791 0.9345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0144 0.0259 0.0734
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.0357 0.2437
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0205 0.0405 0.079
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0336 0.0716 0.2385
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344
Onchocerca volvulus 0.0096 0.0146 0.0382
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0256 0.0525 0.1853
Brugia malayi jmjC domain containing protein 0.0039 0.0011 0.0035
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0185 0.0357 0.1229
Loa Loa (eye worm) hypothetical protein 0.0144 0.0259 0.0854
Mycobacterium ulcerans aldehyde dehydrogenase 0.0256 0.0525 0.1825
Plasmodium vivax hypothetical protein, conserved 0.0122 0.0208 0.4995
Loa Loa (eye worm) hypothetical protein 0.0196 0.0383 0.127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0015 0.0033
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0655 0.1473 0.4924
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0401 0.0869 0.0868
Toxoplasma gondii PHD-finger domain-containing protein 0.004 0.0013 0.0058
Mycobacterium tuberculosis Conserved protein 0.0185 0.0357 0.1258
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Trypanosoma brucei hypothetical protein, conserved 0.0185 0.0357 0.2437
Onchocerca volvulus Bifunctional polynucleotide phosphatase\/kinase homolog 0.0051 0.0039 0.0066
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0205 0.0405 0.0404
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0015 0.0018
Echinococcus granulosus sodium and chloride dependent glycine 0.0205 0.0405 0.079
Onchocerca volvulus Cathepsin F homolog 0.0144 0.0259 0.0715
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0205 0.0405 0.1354
Plasmodium falciparum thioredoxin reductase 0.0047 0.003 0.0482
Schistosoma mansoni jumonji domain containing protein 0.0318 0.0674 0.1314
Mycobacterium ulcerans esterase/lipase LipP 0.0185 0.0357 0.1229
Loa Loa (eye worm) histone methyltransferase 0.0044 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0423 0.0923 0.3081
Echinococcus multilocularis JmjC domain containing protein 4 0.0039 0.0011 0.001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0205 0.0405 0.079
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0144 0.0259 0.6291
Trichomonas vaginalis glutaminase, putative 0.0273 0.0566 0.1636
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0017 0.0052
Loa Loa (eye worm) jmjC domain-containing protein 0.0253 0.0518 0.172
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0015 0.0051
Echinococcus granulosus cathepsin l cysteine peptidase 0.0144 0.0259 0.0504
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0017 0.003
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.001 0.0017
Brugia malayi Importin beta-1 subunit 0.0061 0.0063 0.0208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0094 0.059
Brugia malayi MH1 domain containing protein 0.0066 0.0075 0.0247
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0017 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0423 0.0923 0.309
Loa Loa (eye worm) hypothetical protein 0.0096 0.0146 0.0475
Onchocerca volvulus 0.147 0.3409 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0185 0.0357 0.1192
Onchocerca volvulus Alhambra homolog 0.0122 0.0208 0.0565
Brugia malayi glutathione reductase 0.0047 0.003 0.0098
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.0131 0.0851
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0114 0.0189 0.1261
Trichomonas vaginalis D-aminoacylase, putative 0.0185 0.0357 0.1021
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0013 0.0021
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0017 0.003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0234 0.0474 0.0473
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0017 0.0016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.121 0.2791 0.9346
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Plasmodium vivax phosphatase, putative 0.0051 0.0039 0.07
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.004
Schistosoma mansoni phd/f-box containing protein 0.0039 0.0011 0.002
Schistosoma mansoni smad1 5 8 and 0.0066 0.0075 0.0144
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344
Trypanosoma cruzi cysteine peptidase, putative 0.0548 0.1219 0.849
Leishmania major cathepsin L-like protease 0.0548 0.1219 0.849
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0095 0.3627
Schistosoma mansoni smad1 5 8 and 0.0066 0.0075 0.0144
Plasmodium vivax hypothetical protein, conserved 0.0205 0.0405 1
Schistosoma mansoni hypothetical protein 0.0048 0.0032 0.006
Schistosoma mansoni smad1 5 8 and 0.0066 0.0075 0.0144
Brugia malayi MH2 domain containing protein 0.0066 0.0075 0.0247
Loa Loa (eye worm) CXXC zinc finger family protein 0.0121 0.0204 0.067
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0205 0.0405 0.079
Toxoplasma gondii PHD-finger domain-containing protein 0.0122 0.0208 0.3851
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0175 0.0617
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0017 0.003
Loa Loa (eye worm) fibroinase 0.0144 0.0259 0.0854
Brugia malayi MH1 domain containing protein 0.0066 0.0075 0.0247
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344
Brugia malayi cathepsin F-like cysteine proteinase 0.0048 0.0031 0.0099
Echinococcus multilocularis tumor protein p63 0.1341 0.3102 0.3101
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0188 0.0363 0.6856
Trichomonas vaginalis set domain proteins, putative 0.147 0.3409 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0077 0.01 0.0193
Plasmodium vivax vivapain-3 0.0074 0.0094 0.2086
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0236 0.0477 0.9066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Echinococcus multilocularis cathepsin L cysteine protease 0.0144 0.0259 0.0258
Schistosoma mansoni glutaminase 0.0273 0.0566 0.1103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0046 0.0028 0.0052
Loa Loa (eye worm) hypothetical protein 0.0096 0.0146 0.0475
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0011 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0017 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0017 0.0016
Schistosoma mansoni hypothetical protein 0.07 0.1581 0.3085
Brugia malayi Cathepsin L-like cysteine proteinase 0.0096 0.0146 0.0487
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0017 0.003
Toxoplasma gondii LsmAD domain-containing protein 0.0102 0.0159 0.2902
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0095 0.3627
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Brugia malayi Papain family cysteine protease containing protein 0.0144 0.0259 0.0865
Schistosoma mansoni alpha-glucosidase 0.0289 0.0604 0.1179
Treponema pallidum sodium- and chloride- dependent transporter 0.121 0.2791 0.5
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0017 0.0052
Plasmodium vivax unspecified product 0.0048 0.0031 0.0486
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0205 0.0405 0.079
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1181 0.2723 0.9604
Brugia malayi CXXC zinc finger family protein 0.0121 0.0204 0.0681
Plasmodium vivax vivapain-2 0.0144 0.0259 0.6291
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0548 0.1219 0.849
Echinococcus multilocularis tar DNA binding protein 0.0321 0.068 0.0679
Brugia malayi Cathepsin L-like precursor 0.0144 0.0259 0.0865
Echinococcus granulosus TGF beta signal transducer SmadC 0.0066 0.0075 0.0144
Loa Loa (eye worm) hypothetical protein 0.0096 0.0146 0.0475
Onchocerca volvulus 0.0144 0.0259 0.0715
Trypanosoma cruzi cruzipain precursor, putative 0.0048 0.0031 0.0147
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0011 0.0013
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0025 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0259 0.0734
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.0259 0.1752
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0011 0.0023
Entamoeba histolytica cysteine protease, putative 0.0074 0.0094 0.3584
Echinococcus multilocularis mothers against decapentaplegic 5 0.0066 0.0075 0.0074
Brugia malayi Latrophilin receptor protein 2 0.0196 0.0383 0.128
Loa Loa (eye worm) hypothetical protein 0.0061 0.0063 0.0197
Brugia malayi nuclear hormone receptor 0.0042 0.0017 0.0052
Echinococcus multilocularis serotonin transporter 0.121 0.2791 0.279
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0017 0.003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0015 0.0051
Brugia malayi MH1 domain containing protein 0.0037 0.0005 0.0012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0017 0.003
Schistosoma mansoni ran 0.0045 0.0025 0.0046
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0205 0.0405 0.079
Schistosoma mansoni Smad4 0.0066 0.0075 0.0144
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0114 0.0189 0.1261
Entamoeba histolytica cysteine proteinase 2 0.0074 0.0094 0.3584
Trypanosoma cruzi cysteine peptidase, putative 0.0548 0.1219 0.849
Schistosoma mansoni DNA polymerase eta 0.0041 0.0015 0.0026
Brugia malayi MH2 domain containing protein 0.0972 0.2226 0.7453
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0044 0.0023 0.0042
Onchocerca volvulus 0.0144 0.0259 0.0715
Echinococcus multilocularis lysine specific demethylase 5A 0.0148 0.0269 0.0268
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0017 0.003
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0039 0.0011 0.002
Trypanosoma brucei unspecified product 0.0041 0.0015 0.0035
Echinococcus granulosus cathepsin L 0.0074 0.0094 0.0181
Loa Loa (eye worm) hypothetical protein 0.0048 0.0031 0.0087
Brugia malayi cathepsin L-like precursor 0.0096 0.0146 0.0487
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0185 0.0357 0.1181
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0032 0.0103
Echinococcus granulosus dnaJ subfamily B 0.0869 0.1982 0.3869
Brugia malayi AF-10 protein 0.004 0.0013 0.0039
Echinococcus granulosus phd:f box containing protein 0.0039 0.0011 0.002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0619 0.1389 0.4643
Echinococcus multilocularis jumonji domain containing 1A 0.0039 0.0011 0.001
Brugia malayi Bromodomain containing protein 0.0122 0.0208 0.0694
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0095 0.0597
Toxoplasma gondii hypothetical protein 0.0103 0.0162 0.2961
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.0716 0.0715
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0196 0.0383 0.128
Schistosoma mansoni hypothetical protein 0.0122 0.0208 0.0405
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0205 0.0405 0.079
Schistosoma mansoni hypothetical protein 0.0196 0.0383 0.0746
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0094 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0144 0.0259 0.0734
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0185 0.0357 0.1258
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0046 0.0028 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.1344

Activities

Activity type Activity value Assay description Source Reference
Kb (binding) = 166 nM Antimuscarinic activity against muscarinic acetylcholine receptor M3 from the ileum of guinea pig ChEMBL. 1447741
Kb (binding) = 4743 nM Antimuscarinic activity test against muscarinic acetylcholine receptor M1 from rabbit vas deferens ChEMBL. 1447741
Kb (binding) > 10000 nM Antimuscarinic activity to muscarinic acetylcholine receptor M2 from atria of guinea pig. ChEMBL. 1447741

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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