Detailed information for compound 1038019

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 434.96 | Formula: C22H31ClN4O3
  • H donors: 1 H acceptors: 3 LogP: 4.65 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2nc(nc(c2cc1OC)N)N1CCC(CC1)C(=O)C1CCCCC1.Cl
  • InChi: 1S/C22H30N4O3.ClH/c1-28-18-12-16-17(13-19(18)29-2)24-22(25-21(16)23)26-10-8-15(9-11-26)20(27)14-6-4-3-5-7-14;/h12-15H,3-11H2,1-2H3,(H2,23,24,25);1H
  • InChiKey: AVXZPBFXCSERAM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0128 0.046
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0295 0.1712 1
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.013 0.0154
Brugia malayi hypothetical protein 0.0163 0.0894 0.2238
Echinococcus multilocularis cathepsin b 0.0054 0.022 0.0259
Onchocerca volvulus Putative cubilin 0.0034 0.0095 0.0554
Schistosoma mansoni smad1 5 8 and 0.0043 0.0146 0.0175
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Brugia malayi Cathepsin L-like precursor 0.0097 0.0487 0.1218
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0295 0.1712 0.2018
Brugia malayi latrophilin 2 splice variant baaae 0.0453 0.2695 0.6742
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Leishmania major cathepsin L-like protease 0.0295 0.1712 0.2466
Loa Loa (eye worm) hypothetical protein 0.0453 0.2695 0.6742
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0204 0.0176
Brugia malayi Peroxidasin 0.0268 0.1545 0.3866
Loa Loa (eye worm) hypothetical protein 0.0213 0.1201 0.3006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0113 0.0445
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.054 0.2942
Trypanosoma cruzi cruzipain precursor, putative 0.0097 0.0487 0.0554
Echinococcus granulosus cathepsin L cysteine proteinase 0.0295 0.1712 0.2018
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0001
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0825 0.12
Schistosoma mansoni hypothetical protein 0.021 0.1184 0.1416
Onchocerca volvulus 0.0197 0.1107 0.6466
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0054 0.022 0.1014
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0054 0.022 0.1082
Echinococcus multilocularis cathepsin L cysteine protease 0.0295 0.1712 0.2018
Echinococcus granulosus protein jagged 2 0.0034 0.0095 0.0112
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0054 0.022 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0056 0.0101
Loa Loa (eye worm) nuclear factor I 0.0024 0.0028 0.007
Schistosoma mansoni hypothetical protein 0.0124 0.0651 0.0779
Brugia malayi MH1 domain containing protein 0.0024 0.0028 0.007
Loa Loa (eye worm) hypothetical protein 0.004 0.013 0.0326
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0204 0.0241
Schistosoma mansoni jumonji/arid domain-containing protein 0.0152 0.0826 0.0988
Entamoeba histolytica hypothetical protein 0.0186 0.1037 0.5991
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0374 0.044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0308 0.0363
Loa Loa (eye worm) hypothetical protein 0.0203 0.1141 0.2855
Echinococcus granulosus protein jagged 1 0.0034 0.0095 0.0112
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0255 0.1466 0.1441
Echinococcus multilocularis lysine specific demethylase 5A 0.015 0.0813 0.0959
Mycobacterium tuberculosis Conserved protein 0.0255 0.1466 0.1441
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0054 0.022 0.1082
Trichomonas vaginalis D-aminoacylase, putative 0.0255 0.1466 0.8528
Plasmodium falciparum glutathione reductase 0.005 0.0192 0.0846
Schistosoma mansoni bromodomain containing protein 0.0072 0.0332 0.0397
Loa Loa (eye worm) hypothetical protein 0.0197 0.1107 0.277
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0673 0.1685
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.022 0.1082
Schistosoma mansoni cathepsin s 0.0097 0.0487 0.0582
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.022 0.1082
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 1
Loa Loa (eye worm) hypothetical protein 0.0663 0.3996 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.022 0.1082
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0125 0.0147
Trichomonas vaginalis D-aminoacylase, putative 0.0255 0.1466 0.8528
Onchocerca volvulus Slit protein homolog 0.0034 0.0095 0.0554
Mycobacterium tuberculosis Probable lipase LipE 0.0255 0.1466 0.1441
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0098 0.0281
Leishmania major hypothetical protein, conserved 0.0255 0.1466 0.2105
Loa Loa (eye worm) hypothetical protein 0.005 0.0192 0.0482
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0192 0.0226
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0136 0.0727 0.1819
Brugia malayi Bromodomain containing protein 0.013 0.069 0.1726
Plasmodium falciparum serine repeat antigen 7 0.0054 0.022 0.1014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0255 0.1466 0.1441
Loa Loa (eye worm) animal heme peroxidase 0.0268 0.1545 0.3866
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0097 0.0487 0.1218
Brugia malayi hypothetical protein 0.0186 0.1037 0.2595
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.081 0.0969
Schistosoma mansoni lamin 0.0254 0.1459 0.1745
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 0.5
Onchocerca volvulus 0.0203 0.1141 0.6664
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0192 0.048
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Brugia malayi MH1 domain containing protein 0.0043 0.0146 0.0365
Brugia malayi notch-like transmembrane receptor 0.0034 0.0095 0.0237
Schistosoma mansoni notch 0.0034 0.0095 0.0113
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.054 0.0633
Echinococcus granulosus smad 0.0043 0.0146 0.0172
Echinococcus granulosus cysteine protease 0.0152 0.0825 0.0972
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.054 0.2942
Loa Loa (eye worm) hypothetical protein 0.0106 0.054 0.1351
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Brugia malayi MH2 domain containing protein 0.0043 0.0146 0.0365
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.013 0.0476
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0668 0.0641
Echinococcus granulosus single minded 2 0.0036 0.0105 0.0124
Schistosoma mansoni Smad4 0.0043 0.0146 0.0175
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0295 0.1712 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0255 0.1466 0.1753
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.007
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0374 0.044
Schistosoma mansoni jumonji domain containing protein 0.004 0.013 0.0156
Schistosoma mansoni cell polarity protein 0.0034 0.0095 0.0113
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0041 0.0133 0.0191
Loa Loa (eye worm) animal heme peroxidase 0.0268 0.1545 0.3866
Loa Loa (eye worm) hypothetical protein 0.0077 0.036 0.09
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Echinococcus multilocularis thyroid hormone receptor alpha 0.0138 0.0738 0.087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0173 0.08
Brugia malayi beta-lactamase family protein 0.0255 0.1466 0.3667
Toxoplasma gondii thioredoxin reductase 0.005 0.0192 0.0846
Trypanosoma cruzi cysteine proteinase, putative 0.0152 0.0825 0.1055
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0054 0.022 0.1082
Onchocerca volvulus Peroxidasin homolog 0.0268 0.1545 0.9024
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0054 0.022 0.1014
Schistosoma mansoni notch 0.0034 0.0096 0.0114
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0663 0.3996 1
Schistosoma mansoni phosphatidylserine receptor 0.004 0.013 0.0156
Brugia malayi cathepsin F-like cysteine proteinase 0.0097 0.0487 0.1218
Giardia lamblia Cathepsin L precursor 0.0054 0.022 0.2242
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0095 0.0237
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0673 0.0805
Brugia malayi cytoplasmic intermediate filament protein 0.0136 0.0727 0.1819
Loa Loa (eye worm) blistered cuticle protein 3 0.0268 0.1545 0.3866
Schistosoma mansoni hypothetical protein 0.0048 0.0177 0.0212
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0105 0.0531
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0204 0.122
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0128 0.0591
Loa Loa (eye worm) hypothetical protein 0.0123 0.0643 0.1609
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0825 0.12
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0231 0.1319 0.3299
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0674 0.0795
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0308 0.0363
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Entamoeba histolytica cysteine protease, putative 0.0054 0.022 0.1133
Echinococcus multilocularis cathepsin b 0.0054 0.022 0.0259
Schistosoma mansoni notch 0.0034 0.0095 0.0113
Brugia malayi F/Y-rich N-terminus family protein 0.0043 0.0146 0.0366
Onchocerca volvulus 0.0268 0.1545 0.9024
Plasmodium vivax unspecified product 0.0152 0.0825 0.4657
Echinococcus granulosus fibropellin Ia 0.0034 0.0095 0.0112
Brugia malayi Cathepsin L-like precursor 0.0197 0.1107 0.277
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.013 0.0186
Trypanosoma cruzi cysteine peptidase, putative 0.1123 0.6854 1
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0192 0.0226
Plasmodium falciparum serine repeat antigen 5 0.0054 0.022 0.1014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0073
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0173 0.0432
Mycobacterium ulcerans esterase/lipase LipP 0.0255 0.1466 1
Leishmania major cathepsin L-like protease 0.0295 0.1712 0.2466
Echinococcus multilocularis lamin 0.0254 0.1459 0.172
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0054 0.022 0.055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0173 0.08
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0029 0.0073
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0034 0.004
Onchocerca volvulus 0.0255 0.1466 0.8562
Onchocerca volvulus 0.0268 0.1545 0.9024
Echinococcus granulosus protein jagged 2 0.0034 0.0095 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0673 0.0805
Loa Loa (eye worm) hypothetical protein 0.0197 0.1107 0.277
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0146 0.0172
Trypanosoma cruzi cysteine protease, putative 0.0152 0.0825 0.1055
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0589 0.0561
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0406 0.2402 0.2832
Echinococcus multilocularis protein jagged 1 0.0034 0.0095 0.0112
Echinococcus granulosus tar DNA binding protein 0.0128 0.0673 0.0794
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Entamoeba histolytica cysteine protease, putative 0.0054 0.022 0.1133
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0825 0.4728
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0113 0.0445
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0173 0.0248
Echinococcus multilocularis Smad4 0.0043 0.0146 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0113 0.0445
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0019 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi cathepsin L-like precursor 0.0197 0.1107 0.277
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0054 0.022 0.1014
Onchocerca volvulus Dual oxidase homolog 0.0268 0.1545 0.9024
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0113 0.0445
Echinococcus multilocularis zinc finger protein 0.0025 0.0037 0.0043
Brugia malayi Cathepsin L-like cysteine proteinase 0.0197 0.1107 0.277
Echinococcus granulosus jumonji domain containing protein 0.0173 0.0953 0.1123
Trypanosoma cruzi major cysteine proteinase, putative 0.0883 0.5362 0.7786
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0095 0.0112
Brugia malayi Cathepsin L-like precursor 0.0295 0.1712 0.4284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.022 0.1082
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0054 0.022 0.1133
Giardia lamblia Cathepsin L-like protease 0.0054 0.022 0.2242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.022 0.1082
Plasmodium vivax vivapain-1 0.0152 0.0825 0.4657
Schistosoma mansoni cathepsin F (C01 family) 0.0295 0.1712 0.2047
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0054 0.022 0.1014
Onchocerca volvulus Peroxidase homolog 0.0268 0.1545 0.9024
Echinococcus multilocularis geminin 0.0179 0.0992 0.117
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Onchocerca volvulus 0.0268 0.1545 0.9024
Brugia malayi Cathepsin L-like precursor 0.0295 0.1712 0.4284
Brugia malayi AF-10 protein 0.0041 0.0133 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.022 0.1082
Loa Loa (eye worm) hypothetical protein 0.0097 0.0487 0.1218
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0668 0.0641
Echinococcus multilocularis cysteine protease 0.0295 0.1712 0.2018
Schistosoma mansoni smad1 5 8 and 0.0043 0.0146 0.0175
Echinococcus granulosus intermediate filament protein 0.0254 0.1459 0.172
Echinococcus granulosus geminin 0.0179 0.0992 0.117
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0146 0.0365
Schistosoma mansoni hypothetical protein 0.0186 0.1037 0.1241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0113 0.0445
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0185 0.0462
Echinococcus multilocularis peroxidasin 0.0268 0.1545 0.1821
Echinococcus multilocularis slit 2 protein 0.0034 0.0095 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0056 0.0101
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0054 0.022 0.1014
Echinococcus granulosus cathepsin l cysteine peptidase 0.0295 0.1712 0.2018
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Trypanosoma cruzi cysteine proteinase, putative 0.0152 0.0825 0.1055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0173 0.0088
Brugia malayi jmjC domain containing protein 0.004 0.013 0.0326
Plasmodium vivax JmjC domain containing protein 0.004 0.013 0.0476
Mycobacterium tuberculosis Conserved protein 0.0255 0.1466 0.1441
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0255 0.1466 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.021 0.1184 0.2962
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0054 0.022 0.1014
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0054 0.022 0.2242
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0374 0.2399
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0673 0.1685
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Brugia malayi jmjC domain containing protein 0.004 0.013 0.0326
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Giardia lamblia Cathepsin L precursor 0.0054 0.022 0.2242
Entamoeba histolytica cysteine proteinase 2 0.0152 0.0825 0.4728
Toxoplasma gondii ABC1 family protein 0.0255 0.1466 0.8517
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0173 0.0088
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0173 0.021
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.013 0.0025
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0054 0.022 0.1014
Loa Loa (eye worm) Notch2 0.0034 0.0095 0.0237
Plasmodium falciparum phd finger protein, putative 0.0124 0.0651 0.3614
Echinococcus multilocularis cysteine protease 0.0295 0.1712 0.2018
Schistosoma mansoni protein phosphatase 2C 0.004 0.013 0.0156
Brugia malayi Papain family cysteine protease containing protein 0.0295 0.1712 0.4284
Trichomonas vaginalis penicillin-binding protein, putative 0.0255 0.1466 0.8528
Onchocerca volvulus 0.0295 0.1712 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0125 0.0147
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0173 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Schistosoma mansoni slit 0.0034 0.0095 0.0113
Echinococcus granulosus lysine specific demethylase 5A 0.0152 0.0826 0.0974
Schistosoma mansoni cathepsin C 0.0054 0.022 0.0263
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0166 0.0691
Echinococcus granulosus peroxidasin 0.0268 0.1545 0.1821
Brugia malayi hypothetical protein 0.0068 0.0307 0.0767
Brugia malayi cathepsin F-like cysteine proteinase 0.0054 0.022 0.055
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.013 0.0156
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0204 0.0241
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.013 0.0154
Brugia malayi cathepsin Z-like cysteine proteinase 0.0054 0.022 0.055
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.013 0.0154
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0113 0.0124
Loa Loa (eye worm) hypothetical protein 0.0255 0.1466 0.3667
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0051 0.0155
Brugia malayi Cathepsin L-like precursor 0.0295 0.1712 0.4284
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Plasmodium falciparum serine repeat antigen 4 0.0054 0.022 0.1014
Loa Loa (eye worm) notch protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) cathepsin B 0.0054 0.022 0.055
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0054 0.022 0.0263
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0054 0.022 0.1014
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0339 0.0399
Entamoeba histolytica cysteine protease, putative 0.0295 0.1712 1
Entamoeba histolytica cysteine protease, putative 0.0054 0.022 0.1133
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0173 0.0432
Loa Loa (eye worm) hypothetical protein 0.0097 0.0487 0.1218
Entamoeba histolytica cysteine proteinase, putative 0.0295 0.1712 1
Onchocerca volvulus 0.0254 0.1459 0.8523
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0673 0.0805
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Plasmodium falciparum cysteine proteinase falcipain 1 0.0152 0.0825 0.4657
Schistosoma mansoni hypothetical protein 0.021 0.1184 0.1416
Brugia malayi Papain family cysteine protease containing protein 0.0152 0.0825 0.2063
Schistosoma mansoni hypothetical protein 0.0179 0.0992 0.1187
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Schistosoma mansoni hypothetical protein 0.0453 0.2695 0.3223
Brugia malayi Cathepsin L-like precursor 0.0295 0.1712 0.4284
Brugia malayi Cathepsin L-like precursor 0.0295 0.1712 0.4284
Schistosoma mansoni zinc finger protein 0.0025 0.0037 0.0044
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0173 0.0203
Onchocerca volvulus 0.0157 0.0859 0.5018
Echinococcus granulosus neural cadherin 0.0034 0.0095 0.0112
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0255 0.1466 0.3667
Echinococcus granulosus microtubule associated protein 2 0.1366 0.8362 0.9857
Loa Loa (eye worm) MH2 domain-containing protein 0.0624 0.3758 0.9402
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.022 0.055
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0173 0.0203
Onchocerca volvulus 0.0034 0.0095 0.0554
Onchocerca volvulus Peroxidasin homolog 0.0268 0.1545 0.9024
Toxoplasma gondii cathepsin CPC1 0.0054 0.022 0.1014
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0095 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.081 0.2026
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0374 0.1941
Toxoplasma gondii cathepsin CPL 0.0295 0.1712 1
Entamoeba histolytica cysteine proteinase, putative 0.0295 0.1712 1
Brugia malayi beta-lactamase family protein 0.0255 0.1466 0.3667
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0128 0.0587
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0589 0.0561
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.022 0.1082
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.022 0.1082
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0097 0.0487 0.1218
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0768 0.0906
Loa Loa (eye worm) hypothetical protein 0.0295 0.1712 0.4284
Brugia malayi Thioredoxin reductase 0.005 0.0192 0.048
Loa Loa (eye worm) hypothetical protein 0.0255 0.1466 0.3667
Echinococcus granulosus lamin 0.0254 0.1459 0.172
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Giardia lamblia Cathepsin L precursor 0.0054 0.022 0.2242
Schistosoma mansoni peroxidasin 0.0268 0.1545 0.1848
Leishmania major hypothetical protein, conserved 0.0106 0.054 0.0748
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0255 0.1466 0.1441
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0166 0.0691
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Loa Loa (eye worm) hypothetical protein 0.0097 0.0487 0.1218
Loa Loa (eye worm) hypothetical protein 0.0254 0.1459 0.3651
Brugia malayi PAS domain containing protein 0.0049 0.0184 0.046
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0054 0.022 0.1014
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0034 0.0095 0.0554
Onchocerca volvulus 0.0295 0.1712 1
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0186 0.1037 0.1223
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Echinococcus multilocularis GPCR, family 2 0.021 0.1184 0.1396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.1107 0.6385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0054 0.022 0.0263
Brugia malayi MH2 domain containing protein 0.0043 0.0146 0.0365
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0177 0.0209
Mycobacterium ulcerans beta-lactamase 0.0255 0.1466 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0177 0.0209
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.022 0.055
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0673 0.0794
Echinococcus granulosus cathepsin L 0.0054 0.022 0.0259
Schistosoma mansoni smad 0.0043 0.0146 0.0175
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0146 0.0172
Echinococcus granulosus cathepsin L cysteine protease 0.0152 0.0825 0.0972
Trypanosoma cruzi hypothetical protein, conserved 0.0255 0.1466 0.2006
Brugia malayi MH1 domain containing protein 0.0024 0.0028 0.007
Schistosoma mansoni notch 0.0034 0.0095 0.0113
Leishmania major cathepsin L-like protease 0.0295 0.1712 0.2466
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0825 0.4728
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0095 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0077 0.0229
Schistosoma mansoni cathepsin F (C01 family) 0.0295 0.1712 0.2047
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0146 0.0172
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0295 0.1712 1
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Echinococcus multilocularis peregrin 0.013 0.069 0.0813
Giardia lamblia Cathepsin L precursor 0.0054 0.022 0.2242
Schistosoma mansoni hypothetical protein 0.0179 0.0992 0.1187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0001
Echinococcus multilocularis phd:f box containing protein 0.004 0.013 0.0154
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Brugia malayi jmjC domain containing protein 0.0152 0.0826 0.2067
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0054 0.022 0.0263
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0054 0.022 0.0158
Echinococcus multilocularis protein jagged 2 0.0034 0.0095 0.0112
Plasmodium vivax serine-repeat antigen (SERA) 0.0054 0.022 0.1014
Trichomonas vaginalis penicillin-binding protein, putative 0.0255 0.1466 0.8528
Echinococcus multilocularis neurogenic locus notch protein 4 0.0034 0.0095 0.0112
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0184 0.022
Brugia malayi Bromodomain containing protein 0.0085 0.0411 0.1028
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0095 0.0112
Echinococcus granulosus neurogenic locus notch protein 4 0.0034 0.0095 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.022 0.1082
Schistosoma mansoni hypothetical protein 0.021 0.1184 0.1416
Brugia malayi cathepsin L precursor 0.0054 0.022 0.055
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0054 0.022 0.055
Onchocerca volvulus 0.0295 0.1712 1
Brugia malayi Animal haem peroxidase family protein 0.0268 0.1545 0.3866
Schistosoma mansoni cellular tumor antigen P53 0.0203 0.1141 0.1364
Echinococcus multilocularis musashi 0.0254 0.1459 0.172
Loa Loa (eye worm) hypothetical protein 0.021 0.1184 0.2962
Schistosoma mansoni thyroid hormone receptor 0.0138 0.0738 0.0882
Entamoeba histolytica cysteine proteinase, putative 0.0197 0.1107 0.6405
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.013 0.0476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0173 0.08
Onchocerca volvulus 0.0034 0.0095 0.0554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.022 0.1082
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0255 0.1466 0.3667
Giardia lamblia PHD finger protein 15 0.0124 0.0651 1
Brugia malayi PHD-finger family protein 0.0031 0.0073 0.0182
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Mycobacterium tuberculosis Probable esterase LipL 0.0255 0.1466 0.1441
Giardia lamblia Cathepsin L precursor 0.0054 0.022 0.2242
Plasmodium vivax hypothetical protein, conserved 0.0255 0.1466 0.8517
Onchocerca volvulus Cathepsin L homolog 0.0295 0.1712 1
Plasmodium falciparum serine repeat antigen 8 0.0054 0.022 0.1014
Mycobacterium ulcerans lipase LipD 0.0255 0.1466 1
Toxoplasma gondii cathepsin B 0.0054 0.022 0.1014
Giardia lamblia Cysteine protease 0.0054 0.022 0.2242
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0042 0.0143 0.0169
Brugia malayi hypothetical protein 0.0106 0.054 0.1351
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.013 0.0326
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.054 0.0633
Brugia malayi Smad1 0.0043 0.0146 0.0365
Echinococcus granulosus beta LACTamase domain containing family member 0.0255 0.1466 0.1728
Trichomonas vaginalis esterase, putative 0.0255 0.1466 0.8528
Plasmodium vivax glutathione reductase, putative 0.005 0.0192 0.0846
Schistosoma mansoni hypothetical protein 0.0041 0.0133 0.016
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.081 0.0955
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0091
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0054 0.022 0.0279
Leishmania major cathepsin L-like protease 0.1123 0.6854 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0651 0.163
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0124 0.0651 0.0779
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 0.2399
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0029 0.0073
Schistosoma mansoni hypothetical protein 0.0128 0.0674 0.0806
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi Cadherin domain containing protein 0.0034 0.0095 0.0237
Echinococcus multilocularis jumonji domain containing protein 0.0173 0.0953 0.1123
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0673 0.0805
Trypanosoma cruzi cysteine peptidase, putative 0.1123 0.6854 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0001
Trypanosoma cruzi cruzipain precursor, putative 0.1123 0.6854 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Plasmodium vivax vivapain-3 0.0152 0.0825 0.4657
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trypanosoma brucei hypothetical protein, conserved 0.0255 0.1466 0.2135
Loa Loa (eye worm) PHD-finger family protein 0.0124 0.0651 0.163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi Muscle positioning protein 4 0.0034 0.0095 0.0237
Onchocerca volvulus 0.0034 0.0095 0.0554
Onchocerca volvulus 0.0295 0.1712 1
Brugia malayi Animal haem peroxidase family protein 0.0268 0.1545 0.3866
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.013 0.0154
Giardia lamblia Cysteine protease 0.0054 0.022 0.2242
Brugia malayi beta-lactamase 0.0255 0.1466 0.3667
Echinococcus granulosus cathepsin l1 0.0197 0.1107 0.1305
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) animal heme peroxidase 0.0268 0.1545 0.3866
Trypanosoma cruzi cysteine peptidase, putative 0.0152 0.0825 0.1055
Onchocerca volvulus 0.0255 0.1466 0.8562
Plasmodium falciparum serine repeat antigen 2 0.0054 0.022 0.1014
Echinococcus multilocularis fat cadherin tumor suppressor 0.0034 0.0095 0.0112
Loa Loa (eye worm) beta-lactamase 0.0255 0.1466 0.3667
Mycobacterium tuberculosis Probable lipase LipD 0.0255 0.1466 0.1441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0825 0.4697
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.021 0.1184 0.1396
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0146 0.0175
Schistosoma mansoni hypothetical protein 0.021 0.1184 0.1416
Echinococcus granulosus phd:f box containing protein 0.004 0.013 0.0154
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0113 0.0162
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0366
Echinococcus granulosus protein jagged 1 0.0034 0.0095 0.0112
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0152 0.0825 0.0986
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Loa Loa (eye worm) animal heme peroxidase 0.0268 0.1545 0.3866
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0054 0.022 0.1014
Entamoeba histolytica hypothetical protein 0.0186 0.1037 0.5991
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0166 0.0762
Leishmania major trypanothione reductase 0.005 0.0192 0.0239
Onchocerca volvulus 0.0295 0.1712 1
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0095 0.0112
Loa Loa (eye worm) hypothetical protein 0.0255 0.1466 0.3667
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Trypanosoma brucei trypanothione reductase 0.005 0.0192 0.0276
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0651 0.3614
Giardia lamblia Cysteine protease 0.0054 0.022 0.2242
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.021 0.1184 0.1396
Trypanosoma cruzi cysteine peptidase, putative 0.0097 0.0487 0.0554
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0042 0.0143 0.0169
Onchocerca volvulus Neurogenic locus notch homolog 0.0034 0.0096 0.0559
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0073
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.022 0.1082
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.013 0.0326
Echinococcus multilocularis microtubule associated protein 2 0.1366 0.8362 0.9857
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Schistosoma mansoni transcription factor LCR-F1 0.0186 0.1037 0.1241
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Echinococcus granulosus slit 2 protein 0.0034 0.0095 0.0112
Echinococcus granulosus jumonji domain containing 1A 0.004 0.013 0.0154
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0054 0.022 0.0263
Echinococcus multilocularis fibropellin Ia 0.0034 0.0095 0.0112
Brugia malayi Animal haem peroxidase family protein 0.0268 0.1545 0.3866
Brugia malayi MH1 domain containing protein 0.0043 0.0146 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0054 0.022 0.055
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0054 0.022 0.2242
Loa Loa (eye worm) hypothetical protein 0.0255 0.1466 0.3667
Giardia lamblia Cathepsin L-like protease 0.0054 0.022 0.2242
Entamoeba histolytica hypothetical protein 0.0054 0.022 0.1133
Onchocerca volvulus 0.0024 0.0029 0.017
Onchocerca volvulus Chorion peroxidase homolog 0.0268 0.1545 0.9024
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0295 0.1712 0.2018
Brugia malayi Cathepsin L-like precursor 0.0295 0.1712 0.4284
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Plasmodium vivax unspecified product 0.0054 0.022 0.1014
Loa Loa (eye worm) jmjC domain-containing protein 0.0256 0.1471 0.368
Echinococcus granulosus zinc finger protein 0.0025 0.0037 0.0043
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0054 0.022 0.1014
Mycobacterium leprae conserved hypothetical protein 0.0255 0.1466 1
Schistosoma mansoni cathepsin B (C01 family) 0.0054 0.022 0.0263
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0589 0.0561
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0651 0.3614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0056 0.0101
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.013 0.0326
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0374 0.1941
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0105 0.0263
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0091
Plasmodium falciparum serine repeat antigen 6 0.0054 0.022 0.1014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0026
Schistosoma mansoni microtubule-associated protein tau 0.1366 0.8362 1
Loa Loa (eye worm) hypothetical protein 0.0249 0.143 0.3579
Loa Loa (eye worm) hypothetical protein 0.0054 0.022 0.055
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0054 0.022 0.2242
Loa Loa (eye worm) transcription factor SMAD2 0.0624 0.3758 0.9402
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0041 0.0133 0.0494
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0054 0.022 0.1014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0024 0.0059
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 0.5
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.013 0.0025
Loa Loa (eye worm) ctsf protein 0.0295 0.1712 0.4284
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0668 0.0641
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi hypoxia-induced factor 1 0.015 0.0816 0.2041
Loa Loa (eye worm) hypothetical protein 0.0048 0.018 0.0449
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0339 0.0399
Echinococcus granulosus notch 0.0034 0.0095 0.0112
Brugia malayi Bromodomain containing protein 0.0045 0.0163 0.0408
Mycobacterium tuberculosis Probable reductase 0.0114 0.0589 0.0561
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0673 0.1685
Loa Loa (eye worm) cysteine protease 0.0295 0.1712 0.4284
Toxoplasma gondii cathepsin CPC2 0.0054 0.022 0.1014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0152 0.0825 0.0986
Leishmania major cathepsin L-like protease 0.0295 0.1712 0.2466
Loa Loa (eye worm) fibroinase 0.0295 0.1712 0.4284
Echinococcus multilocularis cathepsin L 0.0054 0.022 0.0259
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi glutathione reductase 0.005 0.0192 0.048
Brugia malayi jmjC domain containing protein 0.004 0.013 0.0326
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1026 0.6249 0.9103
Onchocerca volvulus 0.0255 0.1466 0.8562
Brugia malayi RNA binding protein 0.0128 0.0673 0.1685
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0173 0.0206
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0674 0.0795
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0054 0.022 0.2242
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0054 0.022 0.0263
Brugia malayi Papain family cysteine protease containing protein 0.0152 0.0825 0.2063
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0192 0.0846
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0034 0.0095 0.0237
Loa Loa (eye worm) hypothetical protein 0.0042 0.0141 0.0353
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0095 0.0112
Onchocerca volvulus 0.0254 0.1459 0.8523
Brugia malayi fibroinase precursor 0.0054 0.022 0.055
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Giardia lamblia Hypothetical protein 0.0054 0.022 0.2242
Leishmania major cathepsin L-like protease 0.1123 0.6854 1
Brugia malayi jmjC domain containing protein 0.004 0.013 0.0326
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0105 0.0124
Onchocerca volvulus Cathepsin L homolog 0.0295 0.1712 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0856 0.5196 0.6125
Schistosoma mansoni jumonji/arid domain-containing protein 0.0152 0.0826 0.0988
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0166 0.0762
Loa Loa (eye worm) jmjC domain-containing protein 0.0152 0.0826 0.2067
Giardia lamblia Cysteine protease 0.0054 0.022 0.2242
Brugia malayi Blistered cuticle protein 3 0.0268 0.1545 0.3866
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0173 0.0853
Loa Loa (eye worm) Smad1 0.0043 0.0146 0.0365
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Plasmodium vivax unspecified product 0.0097 0.0487 0.2623
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0073
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0186 0.1037 0.1223
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0204 0.0176
Brugia malayi Calcitonin receptor-like protein seb-1 0.0663 0.3996 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0295 0.1712 0.2018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0095 0.0237
Onchocerca volvulus 0.0034 0.0095 0.0554
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0651 0.3614
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0146 0.0365
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.013 0.0546
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.022 0.1082
Giardia lamblia Encystation-specific protease 0.0054 0.022 0.2242
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0054 0.022 0.1014
Loa Loa (eye worm) acetyltransferase 0.015 0.081 0.2026
Trypanosoma brucei cysteine peptidase C (CPC) 0.0054 0.022 0.0317
Loa Loa (eye worm) hypothetical protein 0.0255 0.1466 0.3667
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0034 0.0041
Brugia malayi follicle stimulating hormone receptor 0.0231 0.1319 0.3299
Onchocerca volvulus 0.0036 0.0105 0.0615
Onchocerca volvulus Peroxidase homolog 0.0268 0.1545 0.9024
Giardia lamblia GTOR 0.0047 0.0173 0.1396
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0374 0.1941
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0054 0.022 0.1082
Plasmodium falciparum cysteine proteinase falcipain 3 0.0295 0.1712 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0123 0.0643 0.0758
Echinococcus multilocularis beta LACTamase domain containing family member 0.0255 0.1466 0.1728
Echinococcus granulosus lamin dm0 0.0254 0.1459 0.172
Brugia malayi hypothetical protein 0.0157 0.0859 0.215
Schistosoma mansoni cathepsin F (C01 family) 0.0197 0.1107 0.1324
Brugia malayi PHD-finger family protein 0.0043 0.0146 0.0366
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0295 0.1712 0.4284
Onchocerca volvulus Alhambra homolog 0.0124 0.0651 0.3805
Echinococcus granulosus tumor protein p63 0.1386 0.8483 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0166 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi Probable ClpP-like protease 0.0079 0.0374 0.0935
Plasmodium vivax serine-repeat antigen (SERA) 0.0054 0.022 0.1014
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 0.1941
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0133 0.0494
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0041 0.0133 0.0494
Brugia malayi Cadherin domain containing protein 0.0034 0.0095 0.0237
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) intermediate filament protein 0.0254 0.1459 0.3651
Brugia malayi TAR-binding protein 0.0128 0.0673 0.1685
Trypanosoma cruzi hypothetical protein, conserved 0.0255 0.1466 0.2006
Loa Loa (eye worm) latrophilin receptor protein 2 0.021 0.1184 0.2962
Trypanosoma cruzi cysteine peptidase, putative 0.1123 0.6854 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0374 0.0447
Leishmania major hypothetical protein, conserved 0.004 0.013 0.0148
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0825 0.4728
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Entamoeba histolytica hypothetical protein 0.0186 0.1037 0.5991
Onchocerca volvulus 0.0054 0.022 0.1283
Echinococcus multilocularis neural cadherin 0.0034 0.0095 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Leishmania major cysteine peptidase A (CPA) 0.0295 0.1712 0.2466
Onchocerca volvulus 0.0295 0.1712 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.1107 0.6385
Echinococcus granulosus neurogenic locus protein delta 0.0034 0.0095 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.022 0.1082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Schistosoma mansoni cathepsin S (C01 family) 0.0054 0.022 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Plasmodium falciparum serine repeat antigen 9 0.0054 0.022 0.1014
Onchocerca volvulus Cathepsin F homolog 0.0295 0.1712 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0034 0.004
Brugia malayi Animal haem peroxidase family protein 0.0268 0.1545 0.3866
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0673 0.0805
Brugia malayi PHD-finger family protein 0.0124 0.0651 0.163
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0173 0.021
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0152 0.0825 0.1055
Entamoeba histolytica cysteine proteinase 1, putative 0.0152 0.0825 0.4728
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0113
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0041 0.0133 0.016
Giardia lamblia Cathepsin L precursor 0.0054 0.022 0.2242
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Onchocerca volvulus Cathepsin L homolog 0.0054 0.022 0.1283
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.0095 0.0237
Schistosoma mansoni notch 0.0034 0.0095 0.0113
Plasmodium falciparum serine repeat antigen 1 0.0054 0.022 0.1014
Brugia malayi cathepsin L-like cysteine proteinase 0.0054 0.022 0.055
Giardia lamblia Hypothetical protein 0.0054 0.022 0.2242
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0254 0.1459 0.3651
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0021 0.0053
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0192 0.0116
Mycobacterium ulcerans hypothetical protein 0.0255 0.1466 1
Loa Loa (eye worm) glutathione reductase 0.005 0.0192 0.048
Brugia malayi EGF-like domain containing protein 0.0034 0.0095 0.0237
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.054 0.0784
Loa Loa (eye worm) hypothetical protein 0.0118 0.0614 0.1537
Echinococcus multilocularis cathepsin L 0.0152 0.0825 0.0972
Loa Loa (eye worm) hypothetical protein 0.0157 0.0859 0.215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0589 0.0561
Toxoplasma gondii PHD-finger domain-containing protein 0.0041 0.0133 0.0494
Echinococcus granulosus delta-like protein 1 0.0034 0.0095 0.0112
Loa Loa (eye worm) RNA binding protein 0.0128 0.0673 0.1685
Echinococcus granulosus peregrin 0.013 0.069 0.0813
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0295 0.1712 1
Onchocerca volvulus 0.0295 0.1712 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0374 0.0935
Brugia malayi MH2 domain containing protein 0.0624 0.3758 0.9402
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0295 0.1712 0.4284
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0054 0.022 0.1133
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.0816 0.2041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.022 0.0263
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0166 0.0691
Schistosoma mansoni intermediate filament proteins 0.0254 0.1459 0.1745
Brugia malayi cathepsin B-like cysteine proteinase 0.0054 0.022 0.055
Echinococcus granulosus PHD finger protein rhinoceros 0.0124 0.0651 0.0768
Schistosoma mansoni phd/f-box containing protein 0.004 0.013 0.0156
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0589 0.3896
Schistosoma mansoni smad1 5 8 and 0.0043 0.0146 0.0175
Plasmodium vivax vivapain-2 0.0295 0.1712 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.054 0.2942
Echinococcus multilocularis notch 0.0034 0.0095 0.0112
Schistosoma mansoni single-minded 0.0049 0.0184 0.022
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.022 0.0158
Schistosoma mansoni laminin gamma-3 chain 0.0034 0.0095 0.0113
Brugia malayi Cytochrome P450 family protein 0.0049 0.0185 0.0462
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.054 0.2942
Onchocerca volvulus 0.0034 0.0095 0.0554
Echinococcus multilocularis tumor protein p63 0.1386 0.8483 1
Entamoeba histolytica cysteine protease, putative 0.0054 0.022 0.1133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.022 0.1082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0041 0.0133 0.0191
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0374 0.2399
Mycobacterium tuberculosis Probable hydrolase 0.0255 0.1466 0.1441
Trypanosoma cruzi cysteine peptidase, putative 0.0295 0.1712 0.2371
Echinococcus multilocularis PHD finger protein rhinoceros 0.0124 0.0651 0.0768
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0029 0.0073
Plasmodium falciparum serine repeat antigen 3 0.0054 0.022 0.1014
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0173 0.0853
Loa Loa (eye worm) hypothetical protein 0.0197 0.1107 0.277
Echinococcus granulosus cathepsin l1 0.0295 0.1712 0.2018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0825 0.4697
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0192 0.0163
Echinococcus granulosus Solute carrier family 22 5 0.1034 0.6302 0.743
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.022 0.055
Brugia malayi hypothetical protein 0.0268 0.1545 0.3866
Loa Loa (eye worm) hypothetical protein 0.0118 0.0614 0.1537
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0095 0.0237
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.021 0.1184 0.1396
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0123 0.0643 0.0758
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0034 0.0095 0.0113
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0071 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.022 0.1082
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.013 0.0476
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Echinococcus multilocularis lamin dm0 0.0254 0.1459 0.172
Entamoeba histolytica cysteine protease, putative 0.0054 0.022 0.1133
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Loa Loa (eye worm) hypothetical protein 0.0163 0.0894 0.2238
Echinococcus granulosus GPCR family 2 0.021 0.1184 0.1396
Brugia malayi cathepsin Z-like cysteine proteinase 0.0054 0.022 0.055
Mycobacterium tuberculosis Conserved protein 0.0255 0.1466 0.1441
Leishmania major cathepsin L-like protease 0.1123 0.6854 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Brugia malayi Intermediate filament tail domain containing protein 0.0254 0.1459 0.3651
Brugia malayi Delta serrate ligand family protein 0.0034 0.0095 0.0237
Entamoeba histolytica hypothetical protein 0.0186 0.1037 0.5991
Giardia lamblia Cathepsin B precursor 0.0054 0.022 0.2242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0098 0.0355
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0146 0.0172
Echinococcus multilocularis smad 0.0043 0.0146 0.0172
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0663 0.3996 1
Schistosoma mansoni notch 0.0034 0.0095 0.0113
Entamoeba histolytica cysteine protease, putative 0.0152 0.0825 0.4728
Echinococcus granulosus cathepsin b 0.0054 0.022 0.0259
Trichomonas vaginalis D-aminoacylase, putative 0.0255 0.1466 0.8528
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.021 0.1184 0.1396
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0668 0.4446
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0054 0.022 0.055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Loa Loa (eye worm) hypothetical protein 0.0255 0.1466 0.3667
Echinococcus granulosus cathepsin b 0.0054 0.022 0.0259
Schistosoma mansoni jumonji domain containing protein 0.0323 0.1884 0.2253
Echinococcus multilocularis protein jagged 1 0.0034 0.0095 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0295 0.1712 1
Brugia malayi Animal haem peroxidase family protein 0.0268 0.1545 0.3866
Echinococcus granulosus cathepsin L 0.0152 0.0825 0.0972
Schistosoma mansoni septate junction protein 0.0034 0.0095 0.0113
Plasmodium vivax vivapain-2 0.0295 0.1712 1
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.013 0.0154
Schistosoma mansoni lamin 0.0254 0.1459 0.1745
Toxoplasma gondii EGF family domain-containing protein 0.0034 0.0095 0.0262
Brugia malayi Cathepsin L-like precursor 0.0197 0.1107 0.277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.022 0.1082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Echinococcus granulosus Smad4 0.0043 0.0146 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1123 0.6854 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0295 0.1712 1
Plasmodium falciparum thioredoxin reductase 0.005 0.0192 0.0846
Mycobacterium leprae Probable lipase LipE 0.0255 0.1466 1
Schistosoma mansoni peroxidasin 0.0268 0.1545 0.1848
Entamoeba histolytica cysteine protease, putative 0.0054 0.022 0.1133
Loa Loa (eye worm) hypothetical protein 0.004 0.013 0.0326
Brugia malayi intermediate filament protein 0.0254 0.1459 0.3651
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0825 0.4728
Brugia malayi jmjC domain containing protein 0.0406 0.2402 0.6011
Brugia malayi Latrophilin receptor protein 2 0.021 0.1184 0.2962
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0237
Toxoplasma gondii preprocathepsin c precursor, putative 0.0054 0.022 0.1014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0152 0.0825 0.0986
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0255 0.1466 0.1753
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0406 0.2402 0.2832
Leishmania major cathepsin L-like protease 0.0295 0.1712 0.2466
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0589 0.0561
Loa Loa (eye worm) hypothetical protein 0.0268 0.1545 0.3866
Schistosoma mansoni thyroid hormone receptor 0.0138 0.0738 0.0882

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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