Detailed information for compound 1053680

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 393.264 | Formula: C19H18Cl2N2O3
  • H donors: 1 H acceptors: 3 LogP: 4.72 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)Cc1ncc(n1C)C(=O)O)OCc1ccccc1.Cl
  • InChi: 1S/C19H17ClN2O3.ClH/c1-22-16(19(23)24)11-21-18(22)10-14-9-15(20)7-8-17(14)25-12-13-5-3-2-4-6-13;/h2-9,11H,10,12H2,1H3,(H,23,24);1H
  • InChiKey: DCOLTGMKTLIRKN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens prostaglandin E receptor 1 (subtype EP1), 42kDa Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.1274 0.4566
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0151 0.152 0.294
Loa Loa (eye worm) hypothetical protein 0.0022 0.0077 0.0148
Brugia malayi Bromodomain containing protein 0.005 0.0395 0.0764
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.022 0.0194
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Trypanosoma cruzi hexose transporter, putative 0.003 0.0167 0.0532
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0425
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0039 0.0007
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.012 0.1176 0.5019
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0213 0.0186
Schistosoma mansoni cpg binding protein 0.0032 0.0189 0.0199
Echinococcus granulosus solute carrier family 22 0.003 0.0167 0.0166
Trypanosoma brucei trypanothione reductase 0.0053 0.0421 0.1455
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0066 0.0045
Schistosoma mansoni glucose transport protein 0.0214 0.2227 0.2619
Plasmodium falciparum glutathione reductase 0.0018 0.0035 0.0007
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0262 0.2764 1
Schistosoma mansoni hypothetical protein 0.0051 0.0404 0.0455
Brugia malayi hypothetical protein 0.0022 0.0077 0.0148
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0039 0.0021
Schistosoma mansoni ap endonuclease 0.004 0.0275 0.0301
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.022 0.0322
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Leishmania major hypothetical protein, conserved 0.0026 0.0117 0.035
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0275 0.0923
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0565 0.0538
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0124 0.1219 0.4366
Schistosoma mansoni polycystin 1-related 0.0022 0.0077 0.0065
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0565 0.0538
Mycobacterium ulcerans hypothetical protein 0.0138 0.1376 0.4723
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0064
Brugia malayi Thioredoxin reductase 0.0053 0.0421 0.0814
Giardia lamblia DNA repair protein RAD52 0.0367 0.3936 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0564 0.1092
Brugia malayi Latrophilin receptor protein 2 0.0151 0.152 0.294
Onchocerca volvulus 0.003 0.0167 0.0178
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0116 0.1128 0.2182
Trypanosoma brucei unspecified product 0.0019 0.0039 0.0064
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0367 0.3936 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0035 0.0016
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Onchocerca volvulus 0.0022 0.0077 0.0019
Loa Loa (eye worm) inositol-1 0.003 0.0162 0.0314
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0167 0.014
Mycobacterium ulcerans hypothetical protein 0.0035 0.022 0.0651
Schistosoma mansoni hypothetical protein 0.0022 0.0077 0.0065
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.0162 0.0222
Echinococcus granulosus GPCR family 2 0.0151 0.152 0.1773
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.1274 0.1487
Schistosoma mansoni alpha glucosidase 0.003 0.0167 0.0173
Brugia malayi beta-lactamase family protein 0.0035 0.022 0.0425
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2613
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.022 0.0839
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0574 0.094
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0151 0.152 0.1504
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0035 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Brugia malayi Sugar transporter family protein 0.003 0.0167 0.0324
Echinococcus multilocularis lysosomal alpha glucosidase 0.0136 0.1348 0.133
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0365 0.0707
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0365 0.0408
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0039 0.0015
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0692 0.0789
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0167 0.0467
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0066 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0338 0.0376
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0638
Entamoeba histolytica acetyltransferase, GNAT family 0.0085 0.078 0.19
Brugia malayi Inositol-1 0.003 0.0162 0.0314
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0243 0.0808
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0275 0.0923
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.022 0.0839
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0541
Plasmodium falciparum protein kinase 7 0.0605 0.66 0.6591
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0066 0.0053
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0167 0.0141
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0243 0.0808
Onchocerca volvulus 0.003 0.0167 0.0178
Echinococcus granulosus calcium dependent protein kinase 0.0062 0.0519 0.0584
Leishmania major protein kinase, putative 0.0066 0.0564 0.1979
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0077 0.0058
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Echinococcus multilocularis geminin 0.0572 0.6232 0.6254
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0066 0.0128
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.022 0.0322
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.003 0.0167 0.0212
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0064
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.1274 0.1896
Echinococcus granulosus dna polymerase eta 0.0019 0.0039 0.0014
Mycobacterium tuberculosis Conserved protein 0.0035 0.022 0.0839
Onchocerca volvulus 0.003 0.0169 0.0181
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0085 0.1497
Brugia malayi Sugar transporter family protein 0.003 0.0167 0.0324
Loa Loa (eye worm) hypothetical protein 0.0066 0.0564 0.1092
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0574 0.2013
Echinococcus granulosus tumor protein p63 0.0359 0.3849 0.4542
Schistosoma mansoni loxhd1 0.0022 0.0077 0.0065
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0541
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Plasmodium vivax hexose transporter 0.0214 0.2227 0.2205
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.022 0.0425
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0066 0.0128
Trichomonas vaginalis glucose transporter, putative 0.003 0.0167 0.0231
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0085 0.0174
Plasmodium falciparum thioredoxin reductase 0.0018 0.0035 0.0007
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0564 0.1092
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Echinococcus multilocularis inositol monophosphatase 1 0.003 0.0162 0.0136
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0035 0.0007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.022 0.0839
Echinococcus granulosus solute carrier family 22 0.003 0.0167 0.0166
Leishmania major DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Echinococcus granulosus lysosomal alpha glucosidase 0.0136 0.1348 0.1569
Leishmania major trypanothione reductase 0.0053 0.0421 0.1455
Plasmodium vivax sugar transporter, putative 0.003 0.0167 0.014
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0043 0.0026
Schistosoma mansoni alpha-glucosidase 0.0117 0.1136 0.1324
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0035 0.0049
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0039 0.0012
Schistosoma mansoni cpg binding protein 0.0036 0.0233 0.0251
Toxoplasma gondii hypothetical protein 0.0042 0.0304 0.042
Trypanosoma brucei sugar transporter, putative 0.003 0.0167 0.0532
Schistosoma mansoni hypothetical protein 0.0326 0.348 0.4107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0066 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0116 0.1128 0.1314
Schistosoma mansoni survival motor neuron protein 0.0051 0.0404 0.0455
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Brugia malayi Pre-SET motif family protein 0.0466 0.5047 0.9764
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0421 0.1455
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0095 0.0895 0.087
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0275 0.0604
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Loa Loa (eye worm) sugar transporter 0.003 0.0167 0.0324
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0117 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0574 0.094
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0167 0.0329
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0167 0.0611
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0167 0.0324
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0167 0.0166
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0275 0.0923
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0317 0.338 0.3989
Schistosoma mansoni hypothetical protein 0.0151 0.152 0.1779
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0167 0.0329
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0117 0.009
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Toxoplasma gondii sugar transporter ST1 0.003 0.0167 0.0213
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0365 0.0576
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0066 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0275 0.0293
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0066 0.0039
Loa Loa (eye worm) hypothetical protein 0.0053 0.0419 0.081
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0076 0.0682 0.0778
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0066 0.0128
Echinococcus granulosus RUN 0.0022 0.0077 0.0058
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0132 0.0105
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0167 0.0166
Schistosoma mansoni inositol monophosphatase 0.003 0.0162 0.0167
Brugia malayi acetyltransferase, GNAT family protein 0.0317 0.338 0.654
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.003 0.0162 0.0449
Onchocerca volvulus 0.003 0.0167 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0066 0.0128
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0067 0.0585 0.0562
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0574 0.2013
Schistosoma mansoni zinc finger protein 0.0031 0.0182 0.019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0066 0.0039
Echinococcus granulosus microtubule associated protein 2 0.077 0.8441 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0066 0.0128
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0035 0.0068
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0039 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0077 0.0049
Loa Loa (eye worm) sugar transporter 0.0214 0.2227 0.4308
Echinococcus multilocularis tumor protein p63 0.0359 0.3849 0.3852
Loa Loa (eye worm) hypothetical protein 0.0057 0.0469 0.0908
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0028 0.0007
Echinococcus granulosus neuropeptide s receptor 0.0374 0.4017 0.4742
Brugia malayi hypothetical protein 0.003 0.0167 0.0324
Echinococcus multilocularis lamin 0.003 0.0169 0.0143
Loa Loa (eye worm) hypothetical protein 0.0086 0.0798 0.1544
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0338 0.0376
Leishmania major alpha glucosidase II subunit, putative 0.003 0.0167 0.0531
Toxoplasma gondii histone lysine methyltransferase SET1 0.0073 0.0653 0.0951
Echinococcus granulosus histone lysine methyltransferase setb 0.0086 0.0798 0.0916
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0117 0.035
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Brugia malayi PHD-finger family protein 0.0034 0.0213 0.0413
Brugia malayi hypothetical protein 0.0017 0.0016 0.003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.012 0.1176 0.5019
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0167 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0066 0.0128
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0117 0.0136
Echinococcus multilocularis dnaJ subfamily B 0.0456 0.4934 0.4946
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0066 0.0045
Echinococcus granulosus histone acetyltransferase KAT2B 0.0095 0.0895 0.1031
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0565 0.0538
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0035 0.0049
Onchocerca volvulus 0.0035 0.022 0.027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0477 0.5169 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Echinococcus multilocularis GPCR, family 2 0.0151 0.152 0.1504
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0079 0.0713 0.138
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0167 0.0231
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0066 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.022 0.0723
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0365 0.034
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0039 0.005
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.003 0.0167 0.0323
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0574 0.2013
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0167 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0564 0.0645
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0167 0.0231
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0574 0.2013
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Echinococcus multilocularis lamin dm0 0.003 0.0169 0.0143
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.055 0.0621
Schistosoma mansoni lipoxygenase 0.0132 0.1302 0.1521
Schistosoma mansoni jumonji domain containing protein 0.0089 0.0827 0.0956
Echinococcus multilocularis peregrin 0.0045 0.0329 0.0304
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0214 0.2227 0.2216
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.0549 0.1063
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0692 0.0669
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Giardia lamblia Sugar-proton symporter 0.003 0.0167 0.0339
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0213 0.0283
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0365 0.1254
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0035 0.0011
Toxoplasma gondii sugar transporter ST3 0.003 0.0167 0.0213
Entamoeba histolytica hypothetical protein 0.0048 0.0365 0.0837
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0066 0.0128
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0638
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0066 0.0053
Echinococcus multilocularis RUN 0.0022 0.0077 0.0049
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0043 0.0019
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0425
Onchocerca volvulus 0.003 0.0167 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0167 0.0231
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0043 0.0026
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0669 0.2359
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1274 0.4364
Onchocerca volvulus 0.003 0.0167 0.0178
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0039 0.0064
Loa Loa (eye worm) hypothetical protein 0.0052 0.0415 0.0802
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0035 0.0007
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0117 0.009
Loa Loa (eye worm) hypothetical protein 0.003 0.0163 0.0316
Plasmodium vivax hypothetical protein, conserved 0.0035 0.022 0.0193
Echinococcus multilocularis neuropeptide receptor A26 0.0374 0.4017 0.4021
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0088 0.017
Echinococcus multilocularis cpg binding protein 0.0036 0.0233 0.0207
Schistosoma mansoni DNA polymerase eta 0.0019 0.0039 0.0021
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.2643 0.2636
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0035 0.0049
Onchocerca volvulus 0.003 0.0167 0.0178
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0574 0.094
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0151 0.152 0.1773
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.0549 0.0526
Entamoeba histolytica hypothetical protein 0.0077 0.0692 0.1675
Entamoeba histolytica hypothetical protein 0.0077 0.0692 0.1675
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.0285 0.1123
Brugia malayi hypothetical protein 0.0022 0.0077 0.0148
Plasmodium vivax proline--tRNA ligase, putative 0.0075 0.0669 0.0643
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.0162 0.0222
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0419 0.0472
Echinococcus multilocularis neutral alpha glucosidase AB 0.003 0.0167 0.0141
Trypanosoma cruzi sugar transporter, putative 0.003 0.0167 0.0532
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.0549 0.1063
Brugia malayi hypothetical protein 0.0251 0.2643 0.5113
Brugia malayi steroid hormone receptor 0.0021 0.0066 0.0128
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0066 0.0039
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0075 0.0669 0.0975
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.2317 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Trypanosoma brucei glucose transporter 1E 0.0066 0.0574 0.2013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0169 0.0328
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0421 0.1716
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0077 0.0148
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0035 0.0049
Brugia malayi latrophilin 2 splice variant baaae 0.0326 0.348 0.6732
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Echinococcus multilocularis musashi 0.003 0.0169 0.0143
Mycobacterium tuberculosis Probable dehydrogenase 0.012 0.1176 0.5019
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0365 0.1254
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0285 0.131
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.012 0.1176 0.5019
Giardia lamblia DINP protein human, muc B family 0.0019 0.0039 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0124 0.1219 0.4366
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2216
Plasmodium vivax SET domain protein, putative 0.0067 0.0585 0.0559
Loa Loa (eye worm) glutaminase 2 0.0272 0.2874 0.556
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0564 0.0638
Loa Loa (eye worm) hypothetical protein 0.0043 0.0309 0.0599
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0565 0.0538
Echinococcus multilocularis neuropeptide s receptor 0.0374 0.4017 0.4021
Brugia malayi jmjC domain containing protein 0.0045 0.0338 0.0654
Plasmodium falciparum hexose transporter 0.0214 0.2227 0.2205
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0275 0.0531
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0151 0.152 0.1504
Brugia malayi hypothetical protein 0.003 0.0167 0.0324
Plasmodium falciparum mitogen-activated protein kinase 2 0.0346 0.3702 0.3685
Schistosoma mansoni protein kinase 0.0066 0.0564 0.0645
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Schistosoma mansoni ap endonuclease 0.004 0.0275 0.0301
Entamoeba histolytica hypothetical protein 0.0104 0.0999 0.2462
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0346 0.3702 0.3685
Schistosoma mansoni glucose transport protein 0.0214 0.2227 0.2619
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0167 0.0231
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0124 0.1219 0.4366
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0365 0.0514
Onchocerca volvulus 0.003 0.0167 0.0178
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0134 0.1327 0.5675
Mycobacterium ulcerans lipase LipD 0.0035 0.022 0.0651
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0066 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.0117 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0066 0.0128
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0035 0.0011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0077 0.0049
Schistosoma mansoni lamin 0.003 0.0169 0.0176
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0134 0.1327 1
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0085 0.2064
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0275 0.0923
Mycobacterium ulcerans glutaminase 0.0272 0.2874 1
Schistosoma mansoni hypothetical protein 0.0023 0.0088 0.0079
Toxoplasma gondii protein kinase, putative 0.0605 0.66 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0167 0.0141
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0066 0.0053
Schistosoma mansoni protein kinase 0.0066 0.0564 0.0645
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0167 0.0324
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0066 0.0039
Brugia malayi Doublecortin family protein 0.0022 0.0077 0.0148
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0039 0.0021
Schistosoma mansoni hypothetical protein 0.0034 0.0213 0.0228
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0574 0.094
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0669 0.2359
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0066 0.0128
Loa Loa (eye worm) hypothetical protein 0.0059 0.0487 0.0942
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0167 0.0611
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0365 0.0339
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0167 0.0531
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0365 0.0847
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0028 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0338 0.0654
Brugia malayi MH2 domain containing protein 0.0121 0.1189 0.23
Plasmodium falciparum histone acetyltransferase GCN5 0.0085 0.078 0.0754
Leishmania major mitochondrial DNA polymerase beta 0.0262 0.2764 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0365 0.1254
Onchocerca volvulus 0.0032 0.0189 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.0798 0.0923
Echinococcus multilocularis dna polymerase eta 0.0019 0.0039 0.0012
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Onchocerca volvulus Alhambra homolog 0.0034 0.0213 0.0259
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0167 0.0231
Brugia malayi hypothetical protein 0.003 0.0167 0.0324
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0066 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0585 0.067
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0028 0.0023
Schistosoma mansoni hypothetical protein 0.0214 0.2227 0.2619
Schistosoma mansoni protein kinase 0.0066 0.0564 0.0645
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0116 0.1128 0.1314
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Echinococcus multilocularis solute carrier family 22 0.003 0.0167 0.0141
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0565 0.0538
Onchocerca volvulus 0.003 0.0167 0.0178
Echinococcus granulosus General substrate transporter 0.0184 0.189 0.2213
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0066 0.0053
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0638
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0086 0.0798 0.0777
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2613
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.022 0.0235
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0167 0.5528
Trichomonas vaginalis maltase-glucoamylase, putative 0.003 0.0167 0.0231
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0574 0.2013
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0285 0.1123
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0043 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0167 0.0231
Schistosoma mansoni glutaminase 0.0272 0.2874 0.3387
Loa Loa (eye worm) hypothetical protein 0.0251 0.2643 0.5113
Trichomonas vaginalis glutaminase, putative 0.0272 0.2874 0.4953
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0904 0.9949 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0066 0.0045
Schistosoma mansoni hypothetical protein 0.0572 0.6232 0.7376
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0275 0.1079
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0549 0.0627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0066 0.0128
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.0549 0.1309
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0317 0.338 0.3379
Entamoeba histolytica protein kinase, putative 0.0066 0.0564 0.1347
Leishmania major DNA polymerase eta, putative 0.0019 0.0039 0.0064
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0338 0.0369
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.003 0.0162 0.0205
Onchocerca volvulus 0.0022 0.0077 0.0019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0112 0.1085 0.1065
Loa Loa (eye worm) hypothetical protein 0.0022 0.0077 0.0148
Echinococcus granulosus solute carrier family 22 0.003 0.0167 0.0166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0066 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.1274 0.1481
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0066 0.0128
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2216
Schistosoma mansoni rab6-interacting 0.0022 0.0077 0.0065
Entamoeba histolytica hypothetical protein 0.0077 0.0692 0.1675
Onchocerca volvulus 0.003 0.0167 0.0178
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0565 0.0538
Schistosoma mansoni glucose transport protein 0.0214 0.2227 0.2619
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0565 0.0817
Onchocerca volvulus 0.0067 0.0585 0.0911
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0095 0.0895 0.132
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.022 0.0322
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0012 0.0023
Schistosoma mansoni hypothetical protein 0.0077 0.0692 0.0796
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0262 0.2764 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0132 0.0124
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0066 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.022 0.0723
Onchocerca volvulus 0.003 0.0167 0.0178
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0112 0.1085 0.1256
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Brugia malayi Bromodomain containing protein 0.0045 0.0329 0.0637
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0243 0.0808
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0077 0.0058
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0565 0.0817
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0066 0.0039
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0117 0.009
Onchocerca volvulus 0.0053 0.0419 0.0619
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0692 0.0796
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0618 0.0709
Giardia lamblia Hexose transporter 0.003 0.0167 0.0339
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0213 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0167 0.0231
Echinococcus granulosus zinc finger protein 0.0031 0.0182 0.0183
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0213 0.0413
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0035 0.0009
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0077 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Echinococcus multilocularis lysosomal alpha glucosidase 0.0136 0.1348 0.133
Entamoeba histolytica protein kinase, putative 0.0066 0.0564 0.1347
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0039 0.0076
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0039 0.0014
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0066 0.0045
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0076
Onchocerca volvulus 0.0051 0.0404 0.0593
Plasmodium falciparum proline--tRNA ligase 0.0075 0.0669 0.0643
Brugia malayi Glycosyl hydrolases family 31 protein 0.003 0.0167 0.0323
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Schistosoma mansoni hypothetical protein 0.0151 0.152 0.1779
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0275 0.0531
Plasmodium vivax glutathione reductase, putative 0.0053 0.0421 0.0394
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Loa Loa (eye worm) hypothetical protein 0.0151 0.152 0.294
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0066 0.0045
Schistosoma mansoni rab6-interacting 0.0022 0.0077 0.0065
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0066 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0574 0.094
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0167 0.0231
Echinococcus granulosus dna polymerase kappa 0.0019 0.0039 0.0014
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Echinococcus granulosus jumonji domain containing protein 0.0048 0.0363 0.0399
Trypanosoma brucei glucosidase, putative 0.003 0.0167 0.0531
Loa Loa (eye worm) hypothetical protein 0.0477 0.5169 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0669 0.2359
Echinococcus multilocularis zinc finger protein 0.0031 0.0182 0.0155
Giardia lamblia Histone acetyltransferase GCN5 0.0085 0.078 0.1908
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0365 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0565 0.0817
Brugia malayi PHD-finger family protein 0.0037 0.0248 0.048
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Onchocerca volvulus Putative transporter 0.003 0.0167 0.0178
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0072 0.006
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0095 0.0895 0.1501
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0035 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0066 0.0128
Brugia malayi Cam kinase protein 1 0.0066 0.0564 0.1092
Onchocerca volvulus 0.003 0.0167 0.0178
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.0549 0.0898
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0541
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0132 0.0132
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0279 0.0299
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0035 0.0049
Toxoplasma gondii exonuclease III APE 0.004 0.0275 0.0376
Schistosoma mansoni alpha-glucosidase 0.0117 0.1136 0.1324
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0039 0.0015
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Plasmodium vivax CDK-related protein kinase 6, putative 0.0909 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0076 0.0682 0.066
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0039 0.0012
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.022 0.0839
Trichomonas vaginalis set domain proteins, putative 0.0531 0.5766 1
Giardia lamblia PHD finger protein 15 0.0034 0.0213 0.0457
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0565 0.0538
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0421 0.0396
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Echinococcus granulosus neuropeptide receptor A26 0.0374 0.4017 0.4742
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0564 0.0923
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0066 0.0053
Brugia malayi CXXC zinc finger family protein 0.0032 0.0189 0.0366
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.022 0.0322
Entamoeba histolytica hypothetical protein 0.0077 0.0692 0.1675
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0028 0.0023
Schistosoma mansoni bromodomain containing protein 0.008 0.0727 0.0838
Brugia malayi major facilitator superfamily protein 0.003 0.0167 0.0324
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0275 0.0248
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0027 0.0128 0.0437
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0346 0.3702 0.5591
Loa Loa (eye worm) hypothetical protein 0.0064 0.0549 0.1063
Mycobacterium tuberculosis Putative ferredoxin reductase 0.012 0.1176 0.5019
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0213 0.0221
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0066 0.0128
Toxoplasma gondii facilitative glucose transporter GT1 0.0214 0.2227 0.3346
Loa Loa (eye worm) acetyltransferase 0.0317 0.338 0.654
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0167 0.0532
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0117 0.0225
Echinococcus granulosus lamin dm0 0.003 0.0169 0.0168
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0066 0.0045
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0162 0.0514
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0037 0.0243 0.0808
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0275 0.0614
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0077 0.0058
Brugia malayi glutathione reductase 0.0053 0.0421 0.0814
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Loa Loa (eye worm) hypothetical protein 0.0053 0.0425 0.0823
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Loa Loa (eye worm) latrophilin receptor protein 2 0.0151 0.152 0.294
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0066 0.0128
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.0549 0.062
Echinococcus granulosus solute carrier family 22 0.003 0.0167 0.0166
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0116 0.1128 0.1314
Echinococcus granulosus intermediate filament protein 0.003 0.0169 0.0168
Brugia malayi hypothetical protein 0.0077 0.0692 0.1338
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2613
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.022 0.0651
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0064
Echinococcus multilocularis microtubule associated protein 2 0.077 0.8441 0.848
Leishmania major glucose transporter, lmgt1 0.0066 0.0574 0.2013
Schistosoma mansoni intermediate filament proteins 0.003 0.0169 0.0176
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0262 0.2764 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0167 0.0231
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0066 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0066 0.0039
Brugia malayi beta-lactamase family protein 0.0035 0.022 0.0425
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0066 0.0039
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0035 0.0049
Brugia malayi nuclear hormone receptor 0.0021 0.0066 0.0128
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0279 0.0253
Onchocerca volvulus 0.003 0.0167 0.0178
Echinococcus multilocularis General substrate transporter 0.0184 0.189 0.1877
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0035 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0066 0.0128
Onchocerca volvulus 0.003 0.0167 0.0178
Echinococcus multilocularis solute carrier family 22 0.003 0.0167 0.0141
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.003 0.0162 0.5318
Trichomonas vaginalis bromodomain-containing protein, putative 0.0095 0.0895 0.1501
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0275 0.0844
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0066 0.0128
Schistosoma mansoni hypothetical protein 0.0151 0.152 0.1779
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0039 0.0076
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0275 0.0248
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0126 0.0243
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0136 0.1348 0.2607
Brugia malayi isocitrate dehydrogenase 0.0018 0.0028 0.0054
Echinococcus multilocularis jumonji domain containing protein 0.0048 0.0363 0.0338
Schistosoma mansoni microtubule-associated protein tau 0.077 0.8441 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0067 0.0585 0.067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Onchocerca volvulus 0.0078 0.0708 0.1126
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0066 0.0128
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0167 0.0231
Schistosoma mansoni hypothetical protein 0.0572 0.6232 0.7376
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0012 0.0023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0116 0.1128 0.1109
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.022 0.0839
Leishmania major glucose transporter, lmgt2 0.0066 0.0574 0.2013
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0365 0.1164
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0565 0.0538
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.022 0.0322
Schistosoma mansoni lamin 0.003 0.0169 0.0176
Loa Loa (eye worm) beta-lactamase 0.0035 0.022 0.0425
Mycobacterium ulcerans sugar transporter 0.003 0.0167 0.0467
Echinococcus granulosus cpg binding protein 0.0036 0.0233 0.0244
Onchocerca volvulus 0.0035 0.022 0.027
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0167 0.0324
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0365 0.0408
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0151 0.152 0.1773
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0565 0.0538
Schistosoma mansoni inositol monophosphatase 0.003 0.0162 0.0167
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0066 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0167 0.0531
Echinococcus granulosus neutral alpha glucosidase AB 0.003 0.0167 0.0166
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0066 0.0128
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0132 0.1302 0.1515
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0365 0.0401
Schistosoma mansoni coup transcription factor 0.0021 0.0066 0.0053
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0095 0.0895 0.132
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0574 0.2013
Brugia malayi Bromodomain containing protein 0.0093 0.0873 0.1689
Plasmodium falciparum phd finger protein, putative 0.0034 0.0213 0.0186
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0067 0.0585 0.0849
Onchocerca volvulus 0.003 0.0167 0.0178
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0167 0.0231
Mycobacterium leprae Probable lipase LipE 0.0035 0.022 0.0768
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0167 0.0467
Trichomonas vaginalis inositol monophosphatase, putative 0.003 0.0162 0.0222
Brugia malayi nuclear receptor NHR-88 0.0021 0.0066 0.0128
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0189 0.0366
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0425
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0028 0.0023
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0299 0.0461
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0425
Loa Loa (eye worm) glutaminase 0.0272 0.2874 0.556
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0116 0.1128 0.1109
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0066 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1274 0.4364
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0035 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0213 0.0413
Echinococcus granulosus peregrin 0.0045 0.0329 0.0358
Schistosoma mansoni sugar transporter 0.003 0.0167 0.0173
Leishmania major hypothetical protein, conserved 0.0035 0.022 0.0723
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0213 0.0187
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.012 0.1176 0.8747
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0116 0.1128 0.1307
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.022 0.0723
Brugia malayi Glycosyl hydrolases family 31 protein 0.0136 0.1348 0.2607
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0162 0.0514
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0162 0.0514
Mycobacterium leprae conserved hypothetical protein 0.0035 0.022 0.0768
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.1274 0.1487
Brugia malayi jmjC domain containing protein 0.0112 0.1085 0.2098
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0167 0.0467
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0066 0.0045
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0028 0.0023
Trypanosoma cruzi glucose transporter, putative 0.003 0.0167 0.0532
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0028 0.0054
Brugia malayi glutaminase DH11.1 0.0272 0.2874 0.556
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.2643 0.3108
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.1274 0.5444
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0365 0.1164
Brugia malayi Pre-SET motif family protein 0.0067 0.0585 0.1133
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0574 0.2013
Schistosoma mansoni lipoxygenase 0.0092 0.0859 0.0995
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0116 0.1128 0.2182
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0128
Onchocerca volvulus 0.003 0.0167 0.0178
Loa Loa (eye worm) intermediate filament protein 0.003 0.0169 0.0328
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0116 0.1128 0.1307
Trypanosoma cruzi hexose transporter 0.0066 0.0574 0.2013
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0549 0.0627
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0167 0.0231
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0077 0.0049
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0039 0.0064
Echinococcus multilocularis solute carrier family 22 0.003 0.0167 0.0141
Echinococcus granulosus lamin 0.003 0.0169 0.0168
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0421 0.0814
Loa Loa (eye worm) hypothetical protein 0.0048 0.0365 0.0707
Leishmania major glucose transporter, lmgt3 0.0066 0.0574 0.2013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.022 0.0235
Onchocerca volvulus 0.003 0.0167 0.0178
Schistosoma mansoni glucose transporter 0.003 0.0167 0.0173
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0324
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0564 0.0541
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.0549 0.1319
Trichomonas vaginalis esterase, putative 0.0035 0.022 0.0322
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0404 0.0782
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0117 0.035
Echinococcus multilocularis calcium dependent protein kinase 0.0062 0.0519 0.0495
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0039 0.005
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0574 0.094
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2216
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0574 0.094
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1189 0.23
Toxoplasma gondii sugar transporter ST2 0.003 0.0167 0.0213
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.022 0.0651
Trichomonas vaginalis sucrase-isomaltase, putative 0.003 0.0167 0.0231
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0167 0.0231
Loa Loa (eye worm) glutathione reductase 0.0053 0.0421 0.0814
Brugia malayi ecdysteroid receptor 0.0021 0.0066 0.0128
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Brugia malayi beta-lactamase 0.0035 0.022 0.0425
Brugia malayi intermediate filament protein 0.003 0.0169 0.0328
Schistosoma mansoni cpg binding protein 0.0036 0.0233 0.0251
Mycobacterium tuberculosis Conserved hypothetical protein 0.0138 0.1376 0.5889
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0425
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.022 0.0839
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0162 0.0514
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0275 1
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Plasmodium falciparum glutathione reductase 0.0053 0.0421 0.0394
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0039 0.0076
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0669 0.2359
Loa Loa (eye worm) hypothetical protein 0.003 0.0169 0.0328
Echinococcus multilocularis solute carrier family 22 0.003 0.0167 0.0141
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0035 0.0049
Schistosoma mansoni hypothetical protein 0.0151 0.152 0.1779
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0134 0.1327 0.5675
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.1274 0.1256
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0077 0.0049
Entamoeba histolytica myo-inositol monophosphatase, putative 0.003 0.0162 0.0316
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0132 0.1302 0.1285
Echinococcus granulosus inositol monophosphatase 1 0.003 0.0162 0.016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0549 0.1063
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0669 0.2359
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0035 0.0049
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0425
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0169 0.0328
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0421 0.0467
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0066 0.0053
Mycobacterium tuberculosis Probable reductase 0.012 0.1176 0.5019
Leishmania major hypothetical protein, conserved 0.003 0.0167 0.0532
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1274 0.4364
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.022 0.0228
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0275 0.0418
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.022 0.0425
Loa Loa (eye worm) bromodomain containing protein 0.0027 0.0137 0.0266
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0421 0.0394
Echinococcus granulosus dnaJ subfamily B 0.0456 0.4934 0.5832
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0466 0.5047 0.9764
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0066 0.0128
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0167 0.0213
Mycobacterium tuberculosis Probable oxidoreductase 0.0134 0.1327 0.5675
Mycobacterium tuberculosis Conserved protein 0.0035 0.022 0.0839
Schistosoma mansoni sugar transporter 0.003 0.0167 0.0173
Brugia malayi Sugar transporter family protein 0.0214 0.2227 0.4308
Onchocerca volvulus 0.0035 0.022 0.027
Trypanosoma brucei glucose transporter 2A 0.0066 0.0574 0.2013
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.022 0.0839
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0104 0.0999 0.2462
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0477 0.5169 1
Mycobacterium ulcerans beta-lactamase 0.0035 0.022 0.0651
Toxoplasma gondii ABC1 family protein 0.0035 0.022 0.0292
Brugia malayi major facilitator superfamily protein 0.003 0.0167 0.0324
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.0798 0.0923
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0066 0.0039
Toxoplasma gondii thioredoxin reductase 0.0053 0.0421 0.0598
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1189 0.23
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Brugia malayi Calcitonin receptor-like protein seb-1 0.0477 0.5169 1
Trichomonas vaginalis conserved hypothetical protein 0.0214 0.2227 0.3824
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0066 0.0128
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0333 0.1137
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0167 0.0532
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0035 0.0049
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0035 0.0032
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0564 0.1979
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0294 0.0268
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0213 0.0283
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0167 0.0231
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0275 0.0418
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0365 0.0339
Echinococcus granulosus geminin 0.0572 0.6232 0.7374
Schistosoma mansoni hypothetical protein 0.0456 0.4934 0.5835
Echinococcus granulosus histone acetyltransferase KAT2B 0.0306 0.3252 0.3832
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2227 0.2613
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0365 0.1983
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0621 0.1202
Onchocerca volvulus 0.003 0.0169 0.0181
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.0549 0.3518
Brugia malayi hypothetical protein 0.0026 0.0117 0.0227
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0167 0.0324
Plasmodium falciparum thioredoxin reductase 0.0053 0.0421 0.0394
Trypanosoma brucei glucose transporter, putative 0.0066 0.0574 0.2013
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0066 0.0128
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0237 0.0785
Loa Loa (eye worm) hypothetical protein 0.0326 0.348 0.6732
Trichomonas vaginalis sugar transporter, putative 0.003 0.0167 0.0231
Schistosoma mansoni sugar transporter 0.003 0.0167 0.0173
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0564 0.1092
Mycobacterium tuberculosis Conserved protein 0.0035 0.022 0.0839
Onchocerca volvulus 0.0531 0.5766 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0064
Schistosoma mansoni sugar transporter 0.003 0.0167 0.0173
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0275 0.0249
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0039 0.0007

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) < -6 Displacement of [3H]PGE2 from EP1 receptor (unknown origin) ChEMBL. 18262416

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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