Detailed information for compound 1127446

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 262.243 | Formula: C13H14F4O
  • H donors: 0 H acceptors: 1 LogP: 4.69 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(C(=O)C(F)(F)F)CCCCc1ccccc1
  • InChi: 1S/C13H14F4O/c14-11(12(18)13(15,16)17)9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7,11H,4-5,8-9H2
  • InChiKey: NWIVHHJMCFVMET-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0045
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0045 0.0045
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0093 0.0456
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0013 0.0023 0.0023
Echinococcus granulosus g protein coupled receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0308 0.1613 0.1613
Brugia malayi Protein kinase domain containing protein 0.0009 0.0003 0.0006
Loa Loa (eye worm) AGC/PKN protein kinase 0.0009 0.0003 0.0002
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0062 0.0288 0.0703
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Schistosoma mansoni nuclear receptor nhr-48 0.0013 0.0023 0.0023
Brugia malayi Niemann-Pick C1 protein precursor 0.0107 0.0532 0.1296
Echinococcus multilocularis sodium leak channel non selective protein 0.0017 0.0045 0.0045
Echinococcus multilocularis transient receptor potential gamma protein 0.0017 0.0045 0.0045
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0101 0.0101
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0325 0.0325
Schistosoma mansoni carbonic anhydrase 0.0062 0.0288 0.0288
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.001 0.0006 0.0006
Echinococcus multilocularis transfer RNA-Gly 0.0017 0.0045 0.0045
Brugia malayi AKH receptor 0.0027 0.0099 0.0241
Loa Loa (eye worm) hhat protein 0.0182 0.0935 0.0934
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0099 0.0099
Mycobacterium tuberculosis Probable esterase LipL 0.0029 0.0109 0.0639
Schistosoma mansoni serine/threonine-protein kinase 0.0017 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0202 0.1843
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0017 0.0045 0.0109
Brugia malayi nuclear receptor RXR 0.0015 0.0032 0.0077
Schistosoma mansoni transient receptor potential channel 4 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0045 0.0045
Brugia malayi Matrixin family protein 0.0078 0.0372 0.0907
Echinococcus granulosus metabotropic glutamate receptor 2 0.001 0.0006 0.0006
Echinococcus granulosus serine/threonine protein kinase 0.0017 0.0043 0.0043
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0101 0.0101
Schistosoma mansoni hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0182 0.0935 0.0935
Schistosoma mansoni opsin-like receptor 0.0027 0.0099 0.0099
Entamoeba histolytica hypothetical protein 0.0039 0.0165 0.1502
Mycobacterium tuberculosis Probable lipase LipE 0.0029 0.0109 0.0639
Echinococcus granulosus hypothetical protein 0.0027 0.0099 0.0099
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus multilocularis GPCR, family 3, C terminal 0.0017 0.0045 0.0045
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0045 0.0045
Schistosoma mansoni sterol O-acyltransferase 1 0.1866 1 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0099 0.0099
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Onchocerca volvulus 0.0043 0.0187 0.1123
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0017 0.0045 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0006 0.0034
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0182 0.0935 0.0934
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0132 0.0666 0.0666
Loa Loa (eye worm) RGC/RGC protein kinase 0.0013 0.0024 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0101 0.0101
Trypanosoma brucei aurora B kinase 0.021 0.1082 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0093 0.0454 0.0454
Schistosoma mansoni serine/threonine-protein kinase 0.0017 0.0043 0.0043
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0143 0.0722 0.0722
Echinococcus granulosus neurogenic locus notch protein 0.0012 0.002 0.002
Leishmania major glycerol uptake protein, putative 0.0182 0.0935 0.8632
Echinococcus multilocularis microtubule associated protein 2 0.05 0.2643 0.2643
Schistosoma mansoni transient receptor potential channel 0.0017 0.0045 0.0045
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0099 0.0099
Brugia malayi calpain 7 0.002 0.0058 0.0142
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0069 0.0325 0.0325
Onchocerca volvulus 0.0027 0.0099 0.0575
Loa Loa (eye worm) hypothetical protein 0.0095 0.0463 0.0463
Trichomonas vaginalis AGC family protein kinase 0.021 0.1082 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0099 0.0099
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0045 0.0045
Brugia malayi Matrixin family protein 0.0188 0.0965 0.2353
Echinococcus granulosus protein kinase c iota type 0.0009 0.0003 0.0003
Leishmania major protein kinase, putative 0.021 0.1082 1
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0011 0.0079
Schistosoma mansoni notch 0.0012 0.002 0.002
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.001 0.0006 0.0006
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0017 0.0045 0.0315
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0182 0.0935 0.0935
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.0054 0.0438
Entamoeba histolytica hypothetical protein 0.0039 0.0165 0.1502
Trypanosoma cruzi kinesin, putative 0.002 0.0058 0.0483
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0069 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Onchocerca volvulus 0.0046 0.0202 0.1212
Schistosoma mansoni opsin-like receptor 0.0027 0.0099 0.0099
Plasmodium falciparum ataxin-2 like protein, putative 0.0019 0.0054 0.0396
Entamoeba histolytica hypothetical protein, conserved 0.0182 0.0935 0.8636
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0045 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0045 0.0045
Toxoplasma gondii hypothetical protein 0.0017 0.0045 0.0315
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Mycobacterium tuberculosis Probable lipase LipD 0.0029 0.0109 0.0639
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Brugia malayi calpain family protein 1 0.0066 0.0307 0.0748
Brugia malayi cation channel family protein 0.0017 0.0045 0.0109
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0093 0.0834
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0101 0.0101
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0101 0.059
Echinococcus multilocularis neuropeptide receptor A26 0.0504 0.2668 0.2668
Loa Loa (eye worm) hypothetical protein 0.0078 0.0372 0.0371
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0017 0.0045 0.0045
Trichomonas vaginalis helicase, putative 0.001 0.0006 0.0034
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0045 0.0045
Schistosoma mansoni notch 0.0012 0.002 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0029 0.0109 0.0639
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis fibropellin Ia 0.0012 0.002 0.002
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0101 0.0101
Echinococcus granulosus slit 2 protein 0.0012 0.002 0.002
Schistosoma mansoni histamine h1 receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.1866 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) RGC/RGC protein kinase 0.0013 0.0024 0.0023
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0069 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0057
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0045 0.0045
Schistosoma mansoni neuropeptide receptor 0.0027 0.0099 0.0099
Leishmania major hypothetical protein, conserved 0.0017 0.0045 0.0357
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0045 0.0045
Trichomonas vaginalis AGC family protein kinase 0.021 0.1082 1
Trypanosoma brucei calpain-like protein, putative 0.002 0.0058 0.0442
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0023 0.0056
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0099 0.0099
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0017 0.0045 0.0045
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0099 0.0099
Brugia malayi Dopamine receptor 0.0027 0.0099 0.0241
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.0054 0.0438
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0109 0.0953
Brugia malayi MBOAT family protein 0.0182 0.0935 0.2278
Brugia malayi MBOAT family protein 0.0182 0.0935 0.2278
Echinococcus multilocularis hypothetical protein 0.002 0.0058 0.0058
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0015 0.0036 0.0232
Echinococcus granulosus nmda type glutamate receptor 0.001 0.0006 0.0006
Echinococcus multilocularis neurogenic locus protein delta 0.0012 0.002 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0099 0.0099
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0099 0.0099
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0036 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0045
Echinococcus granulosus carbonic anhydrase 0.0062 0.0288 0.0288
Echinococcus multilocularis atrial natriuretic peptide receptor 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Trypanosoma cruzi kinesin, putative 0.002 0.0058 0.0483
Brugia malayi nuclear hormone receptor family member nhr-6 0.0013 0.0023 0.0056
Echinococcus multilocularis nmda type glutamate receptor 0.001 0.0006 0.0006
Echinococcus granulosus glutamate receptor 2 0.001 0.0006 0.0006
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0017 0.0045 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0442
Schistosoma mansoni vesicular amine transporter 0.0053 0.0236 0.0236
Onchocerca volvulus 0.0013 0.0023 0.0104
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0101 0.0101
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0045 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0099 0.0099
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0099 0.0241
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0013 0.0023 0.0023
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0101 0.059
Leishmania major hypothetical protein, unknown function 0.0017 0.0045 0.0357
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0017 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0101 0.0101
Trichomonas vaginalis esterase, putative 0.0029 0.0109 0.0985
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0006 0.0034
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0016 0.0016
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0039 0.0165 0.1471
Onchocerca volvulus 0.0013 0.0023 0.0104
Schistosoma mansoni cell polarity protein 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0039 0.0165 0.0165
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0099 0.0099
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0016 0.0016
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0317 0.1658 0.1658
Echinococcus multilocularis carbonic anhydrase 0.0062 0.0288 0.0288
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0017 0.0045 0.0109
Loa Loa (eye worm) AUR protein kinase 0.021 0.1082 0.1081
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0182 0.0935 0.0935
Giardia lamblia Aurora kinase 0.021 0.1082 1
Echinococcus granulosus sex peptide receptor 0.0027 0.0099 0.0099
Onchocerca volvulus Poor gastrulation protein homolog 0.0017 0.0045 0.024
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0182 0.0935 0.8636
Echinococcus granulosus mitogen activated protein kinase 3 0.0039 0.0165 0.0165
Entamoeba histolytica protein kinase, putative 0.021 0.1082 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0109 0.0913
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.002 0.0058 0.0442
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0099 0.0099
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0101 0.0101
Echinococcus multilocularis geminin 0.027 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.1684 0.9019 0.9019
Mycobacterium ulcerans lipase LipD 0.0029 0.0109 0.1415
Brugia malayi Serotonin receptor 0.0027 0.0099 0.0241
Brugia malayi Protein kinase domain containing protein 0.0009 0.0003 0.0006
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0923 0.492 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0087 0.0087
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0045 0.0045
Trichomonas vaginalis AGC family protein kinase 0.001 0.0009 0.0063
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0098 0.0098
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0011
Echinococcus granulosus hyperpolarization activated cyclic 0.0017 0.0045 0.0045
Echinococcus granulosus fibropellin Ia 0.0012 0.002 0.002
Schistosoma mansoni laminin gamma-3 chain 0.0012 0.002 0.002
Brugia malayi MBOAT family protein 0.0182 0.0935 0.2278
Loa Loa (eye worm) ion channel NompC 0.0017 0.0045 0.0044
Mycobacterium tuberculosis Conserved protein 0.0029 0.0109 0.0639
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0182 0.0935 0.0935
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0099 0.0099
Echinococcus granulosus nuclear receptor nhr 48 0.0013 0.0023 0.0023
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0045 0.0045
Echinococcus multilocularis Niemann Pick C1 protein 0.0107 0.0532 0.0532
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0099 0.0241
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0015 0.0032 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0101 0.0247
Echinococcus multilocularis protein jagged 1 0.0012 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Brugia malayi protein kinase C II. 0.0009 0.0003 0.0006
Echinococcus granulosus serine:threonine protein kinase 12 B 0.021 0.1082 0.1082
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0011
Echinococcus granulosus notch 0.0012 0.002 0.002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0099 0.0099
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0017 0.0045 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.0022 0.0073 0.0652
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0032 0.0127 0.108
Echinococcus multilocularis nervana 2 0.0013 0.0021 0.0021
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Echinococcus multilocularis hyperpolarization activated cyclic 0.0017 0.0045 0.0045
Giardia lamblia High cysteine protein 0.0012 0.002 0.008
Schistosoma mansoni hypothetical protein 0.0308 0.1613 0.1613
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0023 0.0104
Brugia malayi Protein kinase domain containing protein 0.0023 0.0078 0.0189
Onchocerca volvulus 0.0191 0.0983 0.6067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis potassium large conductance calcium activated 0.0017 0.0045 0.0045
Echinococcus granulosus microtubule associated protein 2 0.05 0.2643 0.2643
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0011 0.0011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0057 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0011 0.0079
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0095 0.0463 0.1129
Brugia malayi hypothetical protein 0.0011 0.0011 0.0027
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0099 0.0099
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Echinococcus multilocularis protein jagged 2 0.0012 0.002 0.002
Onchocerca volvulus 0.0017 0.0045 0.0239
Schistosoma mansoni notch 0.0012 0.002 0.002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0099 0.0575
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis protein patched 0.0046 0.0202 0.0202
Echinococcus granulosus o acyltransferase membrane bound domain 0.0182 0.0935 0.0935
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0017 0.0045 0.0045
Schistosoma mansoni zinc finger protein 0.0013 0.0023 0.0023
Brugia malayi hypothetical protein 0.0017 0.0045 0.0109
Entamoeba histolytica PH domain containing protein kinase, putative 0.0017 0.0043 0.0373
Loa Loa (eye worm) hypothetical protein 0.0078 0.0372 0.0371
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0099 0.0099
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0045 0.0045
Brugia malayi Ets-domain containing protein 0.0049 0.0217 0.053
Loa Loa (eye worm) carbonic anhydrase 3 0.0132 0.0666 0.0666
Echinococcus multilocularis slit 2 protein 0.0012 0.002 0.002
Brugia malayi Dopamine receptor protein 2 0.0027 0.0099 0.0241
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0143 0.0722 0.1759
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0017 0.0045 0.0357
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0031
Onchocerca volvulus 0.0027 0.0099 0.0575
Leishmania major carbonic anhydrase-like protein 0.0132 0.0666 0.6136
Trypanosoma cruzi glycerol uptake protein, putative 0.0182 0.0935 0.8632
Echinococcus multilocularis tyrosine kinase 0.0013 0.0024 0.0024
Brugia malayi nuclear receptor NHR-88 0.0013 0.0023 0.0056
Onchocerca volvulus Matrilysin homolog 0.0172 0.0882 0.5439
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0017 0.0045 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0099 0.0099
Trypanosoma cruzi GUP1, putative 0.0182 0.0935 0.8632
Brugia malayi serine/threonine protein kinase 6 0.021 0.1082 0.2637
Echinococcus multilocularis cpg binding protein 0.0046 0.0201 0.0201
Onchocerca volvulus 0.0012 0.002 0.0083
Entamoeba histolytica hypothetical protein 0.0182 0.0935 0.8636
Loa Loa (eye worm) hypothetical protein 0.0049 0.0219 0.0218
Echinococcus granulosus Protein kinase C brain isozyme 0.0009 0.0003 0.0003
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0045 0.0239
Leishmania major glycerol uptake protein, putative 0.0182 0.0935 0.8632
Brugia malayi nuclear receptor RXR 0.0013 0.0023 0.0056
Echinococcus granulosus neuropeptide receptor A26 0.0504 0.2668 0.2668
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Giardia lamblia Histone acetyltransferase GCN5 0.003 0.0112 0.0945
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0087 0.0087
Echinococcus granulosus defective proboscis extension response 0.0036 0.0145 0.0145
Trypanosoma cruzi Protein kinase B 0.0017 0.0043 0.0338
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Echinococcus granulosus neurogenic locus protein delta 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0202 0.0201
Trichomonas vaginalis AGC family protein kinase 0.021 0.1082 1
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.021 0.1082 1
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0182 0.0935 0.0935
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0017 0.0045 0.0044
Brugia malayi p70 ribosomal S6 kinase beta 0.0022 0.0071 0.0173
Loa Loa (eye worm) RGC/RGC protein kinase 0.0013 0.0024 0.0023
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0045 0.0045
Echinococcus multilocularis calpain 7 (C02 family) 0.002 0.0058 0.0058
Loa Loa (eye worm) latrophilin receptor protein 2 0.0143 0.0722 0.0721
Brugia malayi G-protein coupled receptor 0.0027 0.0099 0.0241
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0045 0.0315
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0093 0.0226
Brugia malayi Calcium binding EGF domain containing protein 0.0012 0.002 0.0048
Schistosoma mansoni septate junction protein 0.0012 0.002 0.002
Echinococcus multilocularis neuropeptide s receptor 0.0504 0.2668 0.2668
Echinococcus multilocularis calpain 0.002 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0009 0.0003 0.0003
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0045 0.0239
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Schistosoma mansoni two-pore calcium channel 0.0017 0.0045 0.0045
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0099 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Leishmania major glycerol uptake protein, putative 0.0182 0.0935 0.8632
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0109 0.0985
Schistosoma mansoni voltage-gated cation channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0099 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0099 0.0099
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0078 0.0372 0.0371
Schistosoma mansoni notch 0.0012 0.002 0.002
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0015 0.0032 0.0032
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0099 0.0099
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0101 0.0101
Trypanosoma cruzi FHA domain containing protein, putative 0.0011 0.0011 0.0044
Toxoplasma gondii LsmAD domain-containing protein 0.0019 0.0054 0.0396
Loa Loa (eye worm) hypothetical protein 0.0182 0.0935 0.0934
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.0023 0.0078 0.0695
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0045 0.0045
Mycobacterium ulcerans esterase/lipase LipP 0.0029 0.0109 0.1415
Echinococcus granulosus neurogenic locus notch protein 4 0.0012 0.002 0.002
Loa Loa (eye worm) glutamate receptor 0.0041 0.0176 0.0175
Trypanosoma cruzi glycerol uptake protein, putative 0.0182 0.0935 0.8632
Trypanosoma cruzi aurora B kinase, putative 0.021 0.1082 1
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0099 0.0099
Echinococcus granulosus voltage gated hydrogen channel 1 0.0017 0.0045 0.0045
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0182 0.0935 0.0935
Echinococcus granulosus fmrfamide receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0046 0.0202 0.0201
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0031
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0182 0.0935 0.0934
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0101 0.0101
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0325 0.0325
Brugia malayi TAR-binding protein 0.0069 0.0325 0.0793
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0306
Loa Loa (eye worm) MBOAT family protein 0.0182 0.0935 0.0934
Echinococcus multilocularis protein kinase c iota type 0.0009 0.0003 0.0003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0099 0.0099
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0023 0.0023
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0032 0.0127 0.108
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0017 0.0045 0.0045
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0935 0.8636
Echinococcus granulosus calpain 7 C02 family 0.002 0.0058 0.0058
Brugia malayi hypothetical protein 0.0013 0.0023 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Schistosoma mansoni hypothetical protein 0.0143 0.0722 0.0722
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0449 0.0449
Schistosoma mansoni myosin xvIII 0.0027 0.0099 0.0099
Schistosoma mansoni protein kinase 0.021 0.1082 0.1082
Echinococcus granulosus twitchin 0.0038 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Onchocerca volvulus 0.0029 0.0109 0.0637
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0044 0.0193 0.0193
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis neurogenic locus protein delta 0.0012 0.002 0.002
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0013 0.0023 0.0056
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Brugia malayi Cadherin domain containing protein 0.0012 0.002 0.0048
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0017 0.0045 0.0045
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0017 0.0045 0.0045
Onchocerca volvulus 0.0027 0.0099 0.0575
Brugia malayi putative neuropeptide receptor 0.0027 0.0099 0.0241
Brugia malayi Muscleblind-like protein 0.0101 0.0498 0.1215
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0109
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0182 0.0935 0.8626
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0132 0.0666 0.6136
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0013 0.0021 0.0021
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0045 0.0045
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0139 0.0702 0.7259
Brugia malayi steroid hormone receptor 0.0028 0.0101 0.0247
Entamoeba histolytica hypothetical protein 0.0039 0.0165 0.1502
Plasmodium vivax SET domain protein, putative 0.0025 0.0087 0.0713
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0045 0.0045
Brugia malayi MBOAT family protein 0.0182 0.0935 0.2278
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0099 0.0099
Mycobacterium ulcerans hydrolase 0.0095 0.0463 0.6542
Loa Loa (eye worm) hypothetical protein 0.0042 0.0179 0.0179
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0325 0.0325
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0325 0.0793
Echinococcus multilocularis aurora kinase A 0.021 0.1082 0.1082
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0182 0.0935 0.0935
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0101 0.0247
Onchocerca volvulus 0.0078 0.0372 0.2271
Loa Loa (eye worm) calpain 0.002 0.0058 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0101 0.0247
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0099 0.0099
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0099 0.0099
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0045 0.0045
Echinococcus granulosus calcium activated potassium channel 0.002 0.0059 0.0059
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0132 0.0666 0.6136
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0101 0.0101
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Echinococcus multilocularis neurogenic locus notch protein 0.0012 0.002 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0087 0.0087
Trichomonas vaginalis AGC family protein kinase 0.021 0.1082 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0143 0.0722 0.0722
Loa Loa (eye worm) glutamate receptor 0.0027 0.0098 0.0098
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Schistosoma mansoni opsin-like receptor 0.0027 0.0099 0.0099
Schistosoma mansoni coup transcription factor 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0101 0.0101
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0093 0.0834
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0202 0.0202
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0182 0.0935 0.0935
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0057 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.011 0.0543 0.0543
Entamoeba histolytica protein kinase domain containing protein 0.021 0.1082 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0011 0.0079
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0039 0.0165 0.0164
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0017 0.0045 0.0045
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0099 0.0099
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0099 0.0241
Schistosoma mansoni hypothetical protein 0.0044 0.0193 0.0193
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0017 0.0045 0.0045
Brugia malayi Protein kinase domain containing protein 0.0771 0.4102 1
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0099 0.0099
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0058 0.0483
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Brugia malayi sulfakinin receptor protein 0.0027 0.0099 0.0241
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0078 0.0372 0.0372
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0045 0.0045
Schistosoma mansoni metabotropic glutamate receptor 0.0051 0.0229 0.0229
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0101 0.0101
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0093 0.1179
Brugia malayi Receptor family ligand binding region containing protein 0.0013 0.0024 0.0058
Echinococcus multilocularis receptor type guanylyl cyclase 0.0013 0.0024 0.0024
Echinococcus multilocularis voltage dependent calcium channel 0.0017 0.0045 0.0045
Onchocerca volvulus 0.0012 0.002 0.0083
Echinococcus granulosus ryanodine receptor 44f 0.0017 0.0045 0.0045
Plasmodium falciparum histone acetyltransferase GCN5 0.003 0.0112 0.0945
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0101 0.0247
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0099 0.0575
Brugia malayi nuclear hormone receptor 0.0028 0.0101 0.0247
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0017 0.0045 0.0045
Loa Loa (eye worm) voltage-dependent calcium channel 0.0017 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus granulosus roundabout 2 0.0036 0.0145 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0101 0.0247
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Loa Loa (eye worm) AUR protein kinase 0.021 0.1082 0.1081
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0013 0.0023 0.0023
Mycobacterium leprae conserved hypothetical protein 0.0029 0.0109 0.2164
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0013 0.0023 0.0023
Echinococcus granulosus neuropeptide s receptor 0.0504 0.2668 0.2668
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0099 0.0099
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0011 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Echinococcus granulosus geminin 0.027 0.1405 0.1405
Echinococcus multilocularis sterol O acyltransferase 1 0.1866 1 1
Echinococcus multilocularis muscleblind protein 0.0101 0.0498 0.0498
Trypanosoma brucei rac serine-threonine kinase, putative 0.0023 0.0078 0.0621
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Plasmodium falciparum serine/threonine protein kinase, putative 0.021 0.1082 1
Schistosoma mansoni serine/threonine protein kinase 0.021 0.1082 0.1082
Loa Loa (eye worm) hypothetical protein 0.0062 0.0288 0.0288
Brugia malayi DKFZp564C0469 protein 0.0011 0.0011 0.0027
Echinococcus multilocularis GA binding protein alpha chain 0.0049 0.0217 0.0217
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0009 0.0003 0.0003
Echinococcus granulosus sodium leak channel non selective protein 0.0017 0.0045 0.0045
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0017 0.0045 0.0045
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.001 0.0006 0.0006
Brugia malayi Matrixin family protein 0.0078 0.0372 0.0907
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0202 0.0202
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0039 0.0165 0.1434
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0449 0.0448
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0032 0.0127 0.115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Brugia malayi G-protein coupled receptor 0.0027 0.0099 0.0241
Brugia malayi cation channel family protein 0.0017 0.0045 0.0109
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0109 0.0913
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.0092
Echinococcus multilocularis neurogenic locus notch protein 4 0.0012 0.002 0.002
Brugia malayi nuclear receptor NHR-88 0.0028 0.0101 0.0247
Loa Loa (eye worm) hypothetical protein 0.0013 0.0024 0.0023
Brugia malayi nuclear hormone receptor 0.0013 0.0023 0.0056
Echinococcus granulosus protein jagged 2 0.0012 0.002 0.002
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0039 0.0165 0.1471
Echinococcus granulosus Immunoglobulin 0.0036 0.0145 0.0145
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0009 0.0003 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0023 0.0023
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Echinococcus granulosus protein kinase C gamma type 0.0009 0.0003 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0099 0.0099
Schistosoma mansoni ets-related 0.0149 0.0755 0.0755
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0132 0.0666 0.0666
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0182 0.0935 0.0935
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0101 0.0247
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0101 0.0101
Schistosoma mansoni amine GPCR 0.0027 0.0099 0.0099
Schistosoma mansoni tyrosine kinase 0.0013 0.0024 0.0024
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0045 0.0045
Echinococcus granulosus protein jagged 1 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0015 0.0032 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0099 0.0099
Echinococcus multilocularis Niemann Pick C1 protein 0.0154 0.078 0.078
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus multilocularis ryanodine receptor 44f 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0002
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0017 0.0045 0.0109
Toxoplasma gondii hypothetical protein 0.0017 0.0045 0.0315
Brugia malayi GnHR receptor homolog 0.0027 0.0099 0.0241
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0045 0.0045
Brugia malayi Delta serrate ligand family protein 0.0012 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Echinococcus multilocularis neurogenic locus notch protein 0.0012 0.002 0.002
Brugia malayi hypothetical protein 0.0036 0.0145 0.0352
Schistosoma mansoni polycystin 1-related 0.0081 0.039 0.039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0162 0.0395
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0045 0.0109
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0536 0.284 0.284
Schistosoma mansoni neuropeptide receptor 0.0027 0.0099 0.0099
Brugia malayi MAP kinase sur-1 0.0039 0.0165 0.0401
Brugia malayi Pre-SET motif family protein 0.0025 0.0087 0.0213
Schistosoma mansoni metabotropic glutamate receptor 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Schistosoma mansoni DNA ligase IV 0.0011 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Brugia malayi notch-like transmembrane receptor 0.0012 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0087 0.0087
Brugia malayi orphan nuclear receptor NR2E1 0.0013 0.0023 0.0056
Loa Loa (eye worm) matrixin family protein 0.0172 0.0882 0.0881
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0045 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Echinococcus granulosus delta-like protein 1 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0057
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Plasmodium vivax ataxin-2 like protein, putative 0.0019 0.0054 0.0396
Schistosoma mansoni topbp1 0.0011 0.0011 0.0011
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.021 0.1082 0.1082
Entamoeba histolytica hypothetical protein 0.0039 0.0165 0.1502
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus multilocularis Immunoglobulin 0.0036 0.0145 0.0145
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0013 0.0024 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Onchocerca volvulus 0.0029 0.0109 0.0637
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.001 0.0006 0.0006
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.021 0.1082 1
Onchocerca volvulus 0.0027 0.0099 0.0575
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0062 0.0288 0.0703
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0099 0.0241
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0017 0.0043 0.0338
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0182 0.0935 0.0935
Loa Loa (eye worm) hypothetical protein 0.0046 0.0202 0.0201
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0029 0.0109 0.0109
Brugia malayi metabotropic GABA-B receptor subtype 2 0.001 0.0006 0.0016
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0182 0.0935 0.0935
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0057 0.0432
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0011 0.0079
Mycobacterium ulcerans hypothetical protein 0.0029 0.0109 0.1415
Loa Loa (eye worm) AUR protein kinase 0.021 0.1082 0.1081
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0099 0.0099
Brugia malayi latrophilin 2 splice variant baaae 0.0308 0.1613 0.3933
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0069 0.0325 0.0325
Entamoeba histolytica protein kinase, putative 0.0023 0.0078 0.0695
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0045 0.0045
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) fli-1 protein 0.0149 0.0755 0.0755
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0101 0.0101
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0325 0.0325
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0017 0.0045 0.0109
Echinococcus multilocularis serine:threonine protein kinase N2 0.0009 0.0003 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0101 0.0247
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0109 0.0109
Echinococcus multilocularis serine:threonine protein kinase N2 0.0009 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus granulosus histone acetyltransferase KAT2B 0.0106 0.0527 0.0527
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0325 0.0325
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0044 0.0193 0.0193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0109 0.0109
Echinococcus granulosus nervana 2 0.0013 0.0021 0.0021
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0017 0.0045 0.0045
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0013 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0306
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0017 0.0045 0.0109
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0165 0.1502
Brugia malayi olfactory channel protein osm-9 0.0017 0.0045 0.011
Brugia malayi voltage-dependent calcium channel 0.0017 0.0045 0.0109
Trypanosoma brucei calpain-like protein, putative 0.002 0.0058 0.0442
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0087 0.0087
Echinococcus granulosus neurogenic locus notch protein 0.0012 0.002 0.002
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0011 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0101 0.0247
Echinococcus multilocularis calpain family protein 1, d 0.0046 0.0202 0.0202
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0023 0.0056
Echinococcus granulosus calpain A 0.0069 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0051 0.0229 0.0228
Trypanosoma cruzi GUP1, putative 0.0182 0.0935 0.8632
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Entamoeba histolytica vacuolar protein sorting 26 0.0182 0.0935 0.8636
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Brugia malayi Matrixin family protein 0.0078 0.0372 0.0907
Schistosoma mansoni topbp1 0.0011 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Schistosoma mansoni zinc finger protein 0.0182 0.0935 0.0935
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0017 0.0045 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.025 0.1297 0.1297
Trichomonas vaginalis transmembrane protein nessy, putative 0.0182 0.0935 0.8636
Echinococcus multilocularis hyperpolarization activated cyclic 0.0017 0.0045 0.0045
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0099 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0101 0.0247
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0045 0.0045
Schistosoma mansoni nuclear receptor 0.0013 0.0023 0.0023
Leishmania major glycerol uptake protein, putative 0.0182 0.0935 0.8632
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0283 0.1475 0.1475
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0032 0.0077
Echinococcus multilocularis voltage dependent calcium channel 0.0017 0.0045 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0093 0.1179
Brugia malayi bZIP transcription factor family protein 0.0051 0.0226 0.0551
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Loa Loa (eye worm) hypothetical protein 0.0143 0.0722 0.0721
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0099 0.0099
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0017 0.0045 0.0045
Loa Loa (eye worm) nuclear hormone receptor 0.0013 0.0023 0.0023
Mycobacterium leprae Probable lipase LipE 0.0029 0.0109 0.2164
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0093 0.1179
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0029 0.0109 0.0639
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0079
Toxoplasma gondii hypothetical protein 0.0182 0.0935 0.8626
Loa Loa (eye worm) hypothetical protein 0.0107 0.0532 0.0531
Loa Loa (eye worm) ryanodine receptor 0.0017 0.0045 0.0044
Brugia malayi beta-lactamase family protein 0.0029 0.0109 0.0266
Echinococcus granulosus g protein coupled receptor 0.0027 0.0099 0.0099
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0029 0.0072
Schistosoma mansoni calpain-7 (C02 family) 0.002 0.0058 0.0058
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0099 0.0099
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0202 0.0201
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0045 0.0045
Onchocerca volvulus 0.0027 0.0099 0.0575
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0093 0.1179
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus granulosus orexin receptor type 2 0.0027 0.0099 0.0099
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0011 0.0011
Brugia malayi CHE-14 protein 0.0046 0.0202 0.0491
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0012 0.002 0.0048
Schistosoma mansoni amine GPCR 0.0027 0.0099 0.0099
Brugia malayi beta-lactamase 0.0029 0.0109 0.0266
Echinococcus granulosus nuclear factor of activated T cells 5 0.0044 0.0193 0.0193
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0062 0.0288 0.0703
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0132 0.0666 0.1624
Brugia malayi hypothetical protein 0.004 0.0168 0.0408
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0045 0.0045
Echinococcus granulosus atrial natriuretic peptide receptor 0.001 0.0006 0.0006
Echinococcus granulosus protein jagged 2 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0029 0.0109 0.0266
Brugia malayi Calcium binding EGF domain containing protein 0.0012 0.002 0.0048
Loa Loa (eye worm) calpain family protein 1 0.0046 0.0202 0.0201
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0449 0.0449
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0045 0.0045
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0093 0.1802
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0771 0.4102 0.4102
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0017 0.0045 0.0109
Brugia malayi Transient-receptor-potential like protein 0.0017 0.0045 0.0109
Echinococcus multilocularis Glutaredoxin protein 5 0.0013 0.0021 0.0021
Onchocerca volvulus 0.0012 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0045 0.0045
Brugia malayi GCC2 and GCC3 family protein 0.0012 0.002 0.0048
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0449 0.0449
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0087 0.0087
Trypanosoma cruzi calpain cysteine peptidase, putative 0.002 0.0058 0.0483
Onchocerca volvulus Neurogenic locus notch homolog 0.0012 0.002 0.0085
Onchocerca volvulus 0.0027 0.0099 0.0575
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0145 0.0352
Echinococcus granulosus protein jagged 1 0.0012 0.002 0.002
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0099 0.0099
Schistosoma mansoni nephrin 0.0036 0.0145 0.0145
Onchocerca volvulus 0.0182 0.0935 0.5768
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis dnaJ subfamily B 0.0317 0.1658 0.1658
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0093 0.0801
Entamoeba histolytica calpain large subunit domain III containing protein 0.002 0.0058 0.0517
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0062 0.0288 0.0288
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Brugia malayi hypothetical protein 0.0015 0.0032 0.0077
Echinococcus multilocularis nuclear receptor nhr 48 0.0013 0.0023 0.0023
Loa Loa (eye worm) RNA binding protein 0.0069 0.0325 0.0325
Brugia malayi neuropeptide F receptor 0.0027 0.0099 0.0241
Brugia malayi Muscle positioning protein 4 0.0012 0.002 0.0048
Entamoeba histolytica protein kinase, putative 0.0022 0.0071 0.0632
Plasmodium vivax serine/threonine protein kinase 6, putative 0.021 0.1082 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0057
Brugia malayi acetyltransferase, GNAT family protein 0.011 0.0543 0.1324
Echinococcus granulosus glutamate receptor 2 0.001 0.0006 0.0006
Trypanosoma brucei glycerol uptake protein, putative 0.0182 0.0935 0.8626
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0023 0.0023
Brugia malayi Dopamine receptor protein 1 0.0027 0.0099 0.0241
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis serine threonine protein kinase 0.0009 0.0003 0.0003
Schistosoma mansoni protein kinase 0.0013 0.0024 0.0024
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0145 0.0145
Echinococcus granulosus o acyltransferase membrane bound domain 0.0182 0.0935 0.0935
Onchocerca volvulus 0.025 0.1297 0.8018
Brugia malayi metabotropic glutamate receptor type 2 0.0051 0.0229 0.0558
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0051 0.0226 0.0226
Brugia malayi RNA binding protein 0.0069 0.0325 0.0793
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi Melatonin receptor type 1A 0.0027 0.0099 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0935 0.8636
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0058 0.0483
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0017 0.0045 0.0045
Leishmania major kinesin, putative 0.002 0.0058 0.0483
Brugia malayi Calcitonin receptor-like protein seb-1 0.0536 0.284 0.6923
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Trypanosoma cruzi glycerol uptake protein, putative 0.0182 0.0935 0.8632
Brugia malayi Hhat protein 0.0182 0.0935 0.2278
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Mycobacterium tuberculosis Probable hydrolase 0.0029 0.0109 0.0639
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Schistosoma mansoni voltage-dependent calcium channel 0.0017 0.0045 0.0045
Schistosoma mansoni patched 1 0.0046 0.0202 0.0202
Echinococcus granulosus Niemann Pick C1 protein 0.0154 0.078 0.078
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0011 0.0000026075
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0093 0.0801
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0015 0.0036 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0006 0.0034
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0012 0.002 0.002
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0132 0.0666 0.1624
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0101 0.0101
Echinococcus granulosus receptor type guanylyl cyclase 0.0013 0.0024 0.0024
Echinococcus multilocularis rac serine:threonine kinase 0.0017 0.0043 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0023 0.0023
Onchocerca volvulus Slit protein homolog 0.0012 0.002 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0101 0.0247
Echinococcus granulosus GPCR family 2 0.0143 0.0722 0.0722
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0017 0.0045 0.0044
Echinococcus granulosus jun protein 0.0051 0.0226 0.0226
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0165 0.1502
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0039 0.0165 0.1434
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0182 0.0935 0.0935
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0045 0.0045
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0099 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0099 0.0099
Schistosoma mansoni microtubule-associated protein tau 0.05 0.2643 0.2643
Toxoplasma gondii aurora kinase 0.021 0.1082 1
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0182 0.0935 0.0935
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0451 0.2382 0.5807
Echinococcus multilocularis conserved hypothetical protein 0.0017 0.0045 0.0045
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0062 0.0288 0.0703
Echinococcus multilocularis jun protein 0.0051 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0009 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0109 0.0953
Echinococcus multilocularis glutamate receptor 2 0.001 0.0006 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0006 0.0034
Onchocerca volvulus 0.0012 0.002 0.0083
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0449 0.0449
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0132 0.0666 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0165 0.0165
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0093 0.1179
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0099 0.0099
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0099 0.0099
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0012 0.002 0.0083
Echinococcus multilocularis glutamate receptor 2 0.001 0.0006 0.0006
Brugia malayi beta-lactamase family protein 0.0029 0.0109 0.0266
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Loa Loa (eye worm) matrixin family protein 0.0188 0.0965 0.0965
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0165 0.1502
Echinococcus granulosus aurora kinase A 0.021 0.1082 0.1082
Echinococcus granulosus thyroid hormone receptor alpha 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Echinococcus granulosus carbonic anhydrase 0.0062 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0054 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0101 0.0101
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0093 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Loa Loa (eye worm) nuclear receptor NHR-67 0.0013 0.0023 0.0023
Echinococcus granulosus neuroglian 0.0036 0.0145 0.0145
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi Guanylyl cyclase protein 23 0.0013 0.0024 0.0058
Echinococcus multilocularis mitogen activated protein kinase 0.0039 0.0165 0.0165
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0101 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0449 0.0449
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0101 0.0101
Schistosoma mansoni hypothetical protein 0.0044 0.0193 0.0193
Brugia malayi serine/threonine kinase 12 0.021 0.1082 0.2637
Schistosoma mansoni hypothetical protein 0.027 0.1405 0.1405
Echinococcus granulosus o acyltransferase membrane bound domain 0.0182 0.0935 0.0935
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0045 0.0045
Trichomonas vaginalis porcupine, putative 0.0182 0.0935 0.8636
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0009 0.0003 0.0003
Onchocerca volvulus 0.004 0.0168 0.1001
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis two pore calcium channel protein 2 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0062 0.0288 0.0288
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Trypanosoma brucei calpain-like protein, putative 0.002 0.0058 0.0442
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Onchocerca volvulus 0.0026 0.0093 0.0535
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Echinococcus multilocularis calpain 5 0.002 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0101 0.0498 0.0498
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0099 0.0099
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0017 0.0045 0.0109
Mycobacterium ulcerans hypothetical protein 0.0026 0.0093 0.1179
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0449 0.0449
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Brugia malayi larval opioid receptor 0.0027 0.0099 0.0241
Echinococcus granulosus calpain A 0.002 0.0058 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) histone methyltransferase 0.0014 0.003 0.003
Brugia malayi tailless protein 0.0013 0.0023 0.0056
Onchocerca volvulus 0.0027 0.0099 0.0575
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0058 0.0483
Brugia malayi topoisomerase 0.0011 0.0011 0.0027
Schistosoma mansoni neuropeptide receptor 0.0027 0.0099 0.0099
Schistosoma mansoni cpg binding protein 0.0046 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus hypothetical protein 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0057
Trypanosoma brucei carbonic anhydrase-like protein 0.0132 0.0666 0.6119
Onchocerca volvulus 0.0309 0.1616 1
Echinococcus granulosus nibrin 0.0011 0.0011 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0011 0.0044
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0182 0.0935 0.0935
Mycobacterium ulcerans beta-lactamase 0.0029 0.0109 0.1415
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0045 0.0391
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0051 0.0229 0.0229
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0165 0.0165
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0101 0.0101
Schistosoma mansoni cell adhesion molecule 0.0036 0.0145 0.0145
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis serotonin receptor 0.0027 0.0099 0.0099
Toxoplasma gondii ABC1 family protein 0.0029 0.0109 0.0913
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0044 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Loa Loa (eye worm) calpain 5 0.002 0.0058 0.0058
Echinococcus granulosus g protein coupled receptor 0.0027 0.0099 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0109 0.0985
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0101 0.0101
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0045 0.0045
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0017 0.0045 0.0045
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0009 0.0003 0.0002
Trypanosoma brucei calpain-like protein, putative 0.002 0.0058 0.0442
Toxoplasma gondii histone lysine methyltransferase SET1 0.0086 0.0416 0.3778
Echinococcus granulosus hyperpolarization activated cyclic 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0031
Loa Loa (eye worm) hhat protein 0.0182 0.0935 0.0934
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0045 0.0045
Brugia malayi ecdysone receptor 0.0013 0.0023 0.0056
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Brugia malayi hypothetical protein 0.0011 0.0011 0.0027
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0011 0.0044
Mycobacterium leprae PROBABLE HYDROLASE 0.0095 0.0463 1
Schistosoma mansoni hypothetical protein 0.0143 0.0722 0.0722
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0145 0.0352
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0015 0.0032 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0101 0.0247
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0093 0.0834
Schistosoma mansoni notch 0.0012 0.002 0.002
Schistosoma mansoni serine/threonine kinase 0.0009 0.0003 0.0003
Brugia malayi hypothetical protein 0.0013 0.0023 0.0056
Brugia malayi Matrixin family protein 0.0078 0.0372 0.0907
Schistosoma mansoni amine GPCR 0.0027 0.0099 0.0099
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0023 0.0078 0.0078
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0101 0.0101
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0017 0.0045 0.0045
Schistosoma mansoni glutamate receptor NMDA 0.001 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0043 0.0187 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0109 0.0985
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0027 0.0098 0.0098
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0099 0.0099
Echinococcus multilocularis nervana 2 0.0013 0.0021 0.0021
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0039 0.0162 0.0162
Entamoeba histolytica hypothetical protein 0.001 0.0006 0.0036
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis sex peptide receptor 0.0027 0.0099 0.0099
Onchocerca volvulus 0.0011 0.0011 0.0029
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0283 0.1475 0.1475
Loa Loa (eye worm) calpain family protein 1 0.0066 0.0307 0.0306
Echinococcus granulosus sodium channel protein 0.0017 0.0045 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0101 0.0101
Echinococcus granulosus neuropeptide receptor 0.0027 0.0099 0.0099
Brugia malayi Pre-SET motif family protein 0.0168 0.0858 0.2092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0101 0.059
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0079
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Echinococcus multilocularis carbonic anhydrase 0.0062 0.0288 0.0288
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0056 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Onchocerca volvulus 0.0027 0.0099 0.0575
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.001 0.0006 0.0006
Entamoeba histolytica protein kinase 2, putative 0.0015 0.0036 0.0309
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus transient receptor potential gamma protein 0.0017 0.0045 0.0045
Leishmania major hypothetical protein, conserved 0.0182 0.0935 0.8632
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus multilocularis GPCR, family 2 0.0143 0.0722 0.0722
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0182 0.0935 0.0935
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0099 0.0099
Plasmodium falciparum carbonic anhydrase 0.0062 0.0288 0.2588
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0099 0.0241
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0045 0.0045
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0182 0.0935 0.0934
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0202 0.0202
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0099 0.0099
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Echinococcus granulosus neural cadherin 0.0012 0.002 0.002
Echinococcus granulosus voltage dependent calcium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) matrix metalloproteinase 0.0078 0.0372 0.0371
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Echinococcus multilocularis serotonin receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis carbonic anhydrase II 0.0132 0.0666 0.0666
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0049 0.0217 0.0217
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0182 0.0935 0.8636
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0057 0.0669
Echinococcus multilocularis calpain A 0.0069 0.0325 0.0325
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0109 0.0985
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0011 0.0044
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0045 0.0044
Echinococcus multilocularis somatostatin receptor 0.0027 0.0099 0.0099
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0015 0.0036 0.0036
Brugia malayi hypothetical protein 0.0015 0.0032 0.0077
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0107 0.0532 0.4903
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0165 0.1502
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0185 0.0948 1
Echinococcus granulosus calpain 5 0.002 0.0058 0.0058
Echinococcus granulosus dnaJ subfamily B 0.0317 0.1658 0.1658
Onchocerca volvulus 0.0025 0.0087 0.0503
Trypanosoma brucei protein kinase, putative 0.0039 0.0165 0.1434
Schistosoma mansoni carbonic anhydrase-related 0.0062 0.0288 0.0288
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0182 0.0935 0.8626
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0099 0.0099
Brugia malayi hypothetical protein 0.0039 0.0165 0.0401
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0009 0.0003 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0099 0.0099
Giardia lamblia Kinase, CMGC MAPK 0.0039 0.0165 0.1434
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0101 0.0101
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0143 0.0722 0.0722
Onchocerca volvulus 0.0028 0.0101 0.059
Schistosoma mansoni transient receptor potential channel 0.0017 0.0045 0.0045
Brugia malayi Latrophilin receptor protein 2 0.0143 0.0722 0.1759
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0017 0.0045 0.0045
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0045 0.0045
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0017 0.0045 0.0045
Echinococcus multilocularis metabotropic glutamate receptor 2 0.001 0.0006 0.0006
Echinococcus multilocularis notch 0.0012 0.002 0.002
Brugia malayi Serotonin receptor 0.0027 0.0099 0.0241
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0029 0.0109 0.1415
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0182 0.0935 0.0935
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.0092
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0101 0.0101
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0017 0.0045 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi hypothetical protein 0.0019 0.0054 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Schistosoma mansoni notch 0.0012 0.002 0.002
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0307 0.0307
Schistosoma mansoni calpain-7 (C02 family) 0.002 0.0058 0.0058
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0045 0.0045
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1513 0.8096 0.8096
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0101 0.0247
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0079
Onchocerca volvulus Putative cubilin 0.0012 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0109
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0165 0.0165
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0017 0.0045 0.0045
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Brugia malayi Ets-domain containing protein 0.0049 0.0217 0.053
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0062 0.0288 0.0703
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Brugia malayi neuropeptide F receptor 0.0027 0.0099 0.0241
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0087 0.0713
Echinococcus multilocularis carbonic anhydrase 0.0062 0.0288 0.0288
Schistosoma mansoni calpain C (C02 family) 0.002 0.0058 0.0058
Schistosoma mansoni calpain (C02 family) 0.002 0.0058 0.0058
Onchocerca volvulus 0.0027 0.0099 0.0575
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0078 0.0695
Entamoeba histolytica PH domain containing protein kinase, putative 0.0017 0.0043 0.0373
Echinococcus granulosus Niemann Pick C1 protein 0.0107 0.0532 0.0532
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0031
Echinococcus granulosus potassium large conductance calcium activated 0.0017 0.0045 0.0045
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0165 0.1471
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0101 0.0101
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0015 0.0036 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0099 0.0099
Echinococcus granulosus expressed conserved protein 0.0101 0.0497 0.0497
Schistosoma mansoni biogenic amine receptor 0.0027 0.0099 0.0099
Echinococcus granulosus allatostatin A receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0101 0.0101
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0182 0.0935 0.0935
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0017 0.0045 0.0045
Brugia malayi Receptor family ligand binding region containing protein 0.0027 0.0098 0.0239
Schistosoma mansoni biogenic amine receptor 0.0027 0.0099 0.0099
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0449 0.1094
Echinococcus granulosus calpain 0.002 0.0058 0.0058
Echinococcus multilocularis nibrin 0.0011 0.0011 0.0011
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0099 0.0099
Onchocerca volvulus 0.011 0.0547 0.3358
Echinococcus multilocularis neuroglian 0.0036 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0182 0.0935 0.0934
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0099 0.0241
Brugia malayi ion channel NompC 0.0017 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Echinococcus multilocularis shaker cognate 0.0017 0.0045 0.0045
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0017 0.0045 0.0315
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0006 0.0034
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0029 0.0109 0.0639
Echinococcus multilocularis mitogen activated protein kinase 3 0.0039 0.0165 0.0165
Brugia malayi small heat shock protein 0.0318 0.1668 0.4066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Schistosoma mansoni biogenic amine receptor 0.0027 0.0099 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0045 0.0045
Brugia malayi Hemopexin family protein 0.011 0.0547 0.1333
Echinococcus multilocularis fat cadherin tumor suppressor 0.0012 0.002 0.002
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0013 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Echinococcus granulosus carbonic anhydrase II 0.0132 0.0666 0.0666
Echinococcus granulosus serine:threonine protein kinase N2 0.0009 0.0003 0.0003
Loa Loa (eye worm) calcium channel 0.0017 0.0045 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus TRP transient receptor potential channel 0.0017 0.0045 0.0045
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0099 0.0099
Echinococcus granulosus neuropeptide receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) beta-lactamase 0.0029 0.0109 0.0109
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.011 0.0543 0.0543
Loa Loa (eye worm) hypothetical protein 0.0318 0.1668 0.1668
Echinococcus multilocularis sodium channel protein 0.0017 0.0045 0.0045
Schistosoma mansoni neuropeptide receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0325 0.0325
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0011 0.0027
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0045 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0101 0.0247
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0017 0.0045 0.0045
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0101 0.0101
Plasmodium falciparum ataxin-2 like protein, putative 0.0019 0.0054 0.0396
Brugia malayi calpain 5 0.002 0.0058 0.0142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Entamoeba histolytica acetyltransferase, GNAT family 0.003 0.0112 0.1016
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0099 0.0099
Echinococcus granulosus GPCR family 3 C terminal 0.0017 0.0045 0.0045
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0009 0.0003 0.0003
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0017 0.0045 0.011
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Brugia malayi RE15519p 0.0027 0.0099 0.0241
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0093 0.1179
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0009 0.0003 0.0002
Echinococcus multilocularis protein jagged 1 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0099 0.0099
Schistosoma mansoni ryanodine receptor related 0.0017 0.0045 0.0045
Loa Loa (eye worm) MBOAT family protein 0.0182 0.0935 0.0934
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0101 0.0101
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0013 0.0023 0.0023
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0109 0.0985
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0182 0.0935 0.0935
Schistosoma mansoni hypothetical protein 0.0027 0.0099 0.0099
Plasmodium vivax calpain, putative 0.002 0.0058 0.0442
Echinococcus granulosus nervana 2 0.0013 0.0021 0.0021
Onchocerca volvulus 0.0013 0.0024 0.0108
Echinococcus granulosus voltage dependent calcium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi Cadherin domain containing protein 0.0012 0.002 0.0048
Treponema pallidum alginate O-acetylation protein (algI) 0.0182 0.0935 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.021 0.1082 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Brugia malayi ORL1-like opioid receptor 0.0027 0.0099 0.0241
Schistosoma mansoni amine GPCR 0.0027 0.0099 0.0099
Mycobacterium ulcerans epoxide hydrolase EphA 0.0139 0.0702 1
Echinococcus multilocularis protein dispatched 1 0.0053 0.0237 0.0237
Schistosoma mansoni calcium-activated potassium channel 0.0017 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0039 0.0165 0.1471
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.001 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0029 0.0109 0.0639
Brugia malayi MBOAT family protein 0.0182 0.0935 0.2278
Echinococcus granulosus tyrosine kinase 0.0013 0.0024 0.0024
Echinococcus granulosus muscleblind protein 0.0101 0.0498 0.0498
Loa Loa (eye worm) acetyltransferase 0.011 0.0543 0.0543
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0058 0.0483
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus shaker cognate 0.0017 0.0045 0.0045
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0099 0.0099
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0023 0.0023
Echinococcus granulosus two pore calcium channel protein 2 0.0017 0.0045 0.0045
Trichomonas vaginalis set domain proteins, putative 0.0191 0.0982 0.9078
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0023 0.0104
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0079
Echinococcus granulosus Glutaredoxin protein 5 0.0013 0.0021 0.0021
Loa Loa (eye worm) CXXC zinc finger family protein 0.0043 0.0187 0.0187
Onchocerca volvulus 0.0029 0.0109 0.0637
Trypanosoma brucei antigen, putative 0.002 0.0058 0.0442
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0017 0.0045 0.024
Loa Loa (eye worm) hypothetical protein 0.0101 0.0498 0.0498
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0182 0.0935 0.8626
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0032 0.0077
Brugia malayi CXXC zinc finger family protein 0.0043 0.0187 0.0456
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0093 0.1802
Onchocerca volvulus Matrix metalloproteinase homolog 0.0172 0.0882 0.5439
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0099 0.0099
Brugia malayi Calcium binding EGF domain containing protein 0.0012 0.002 0.0048
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0101 0.0101
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0006 0.0034
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0099 0.0099
Echinococcus granulosus carbonic anhydrase 0.0062 0.0288 0.0288
Schistosoma mansoni amine GPCR 0.0027 0.0099 0.0099
Echinococcus multilocularis protein kinase c epsilon type 0.0009 0.0003 0.0003
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0045 0.0315
Echinococcus granulosus rho-associated protein kinase 1 0.025 0.1297 0.1297
Schistosoma mansoni hypothetical protein 0.0062 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0011 0.0011 0.0079
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.001 0.0006 0.0006
Brugia malayi diacylglycerol acyltransferase 0.0182 0.0935 0.2278
Echinococcus multilocularis serine:threonine protein kinase 38 0.0009 0.0003 0.0003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0182 0.0935 0.8626
Brugia malayi Metabotropic glutamate receptor precursor. 0.0027 0.0098 0.0239
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Brugia malayi hypothetical protein 0.0027 0.0099 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0101 0.0247
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0099 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0099 0.0099
Schistosoma mansoni cpg binding protein 0.0046 0.0201 0.0201
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0099 0.0241
Schistosoma mansoni transient receptor potential channel 0.0017 0.0045 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0093 0.0226
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0093 0.0226
Onchocerca volvulus 0.0247 0.1282 0.7928
Echinococcus granulosus cpg binding protein 0.0046 0.0201 0.0201
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0045 0.0391
Brugia malayi calpain family protein 1 0.0066 0.0307 0.0748
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0039 0.0165 0.1471
Echinococcus granulosus serine threonine protein kinase nrc 0.0015 0.0036 0.0036
Loa Loa (eye worm) AGC/AKT protein kinase 0.0023 0.0078 0.0077
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis expressed conserved protein 0.0101 0.0497 0.0497
Brugia malayi hypothetical protein 0.0012 0.0018 0.0044
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0182 0.0935 0.0935
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0045 0.0315
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis muscleblind protein 1 0.0101 0.0498 0.0498
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0022 0.0071 0.007
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0011 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0099 0.0099
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0451 0.2382 0.2382
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0045 0.0045
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0017 0.0045 0.0045
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0325 0.0325
Trypanosoma brucei PAB1-binding protein , putative 0.0019 0.0054 0.0396
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0045 0.0045
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0099 0.0099
Schistosoma mansoni nuclear receptor 0.0013 0.0023 0.0023
Onchocerca volvulus 0.0027 0.0099 0.0575
Loa Loa (eye worm) hypothetical protein 0.0062 0.0288 0.0288
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0017 0.0045 0.011
Schistosoma mansoni tyrosine kinase 0.0013 0.0024 0.0024
Echinococcus multilocularis beta LACTamase domain containing family member 0.0029 0.0109 0.0109
Schistosoma mansoni Mername-AA248 (C02 family) 0.002 0.0058 0.0058
Brugia malayi conserved hypotetical protein 0.0013 0.0023 0.0056
Echinococcus granulosus NDR protein kinase 0.0009 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0101 0.0101
Brugia malayi nuclear receptor NHR-67 0.0013 0.0023 0.0056
Echinococcus granulosus beta LACTamase domain containing family member 0.0029 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Schistosoma mansoni gabp alpha 0.0049 0.0217 0.0217
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0045 0.0045
Onchocerca volvulus 0.0027 0.0099 0.0575
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0011
Echinococcus granulosus two pore calcium channel protein 1 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) MBOAT family protein 0.0182 0.0935 0.0934
Schistosoma mansoni jun-related protein 0.0041 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0109
Trichomonas vaginalis bromodomain-containing protein, putative 0.0032 0.0127 0.115
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0093 0.1179
Schistosoma mansoni hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0027 0.0098 0.0098
Brugia malayi Cyclic-nucleotide gated cation channel 0.0017 0.0045 0.0109
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0064 0.0299 0.0299
Echinococcus multilocularis two pore calcium channel protein 1 0.0017 0.0045 0.0045
Toxoplasma gondii hypothetical protein 0.0062 0.0288 0.2588
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0449 0.0449
Echinococcus granulosus somatostatin receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Schistosoma mansoni atypical protein kinase C 0.0009 0.0003 0.0003
Toxoplasma gondii EGF family domain-containing protein 0.0012 0.002 0.008
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0045 0.0315
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0006 0.0034
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0168 0.0858 0.0858
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0017 0.0045 0.0109
Echinococcus granulosus mixed lineage leukemia protein mll 0.0012 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0029 0.0109 0.0639
Brugia malayi serine/threonine-protein kinase 6 0.021 0.1082 0.2637
Echinococcus multilocularis neural cadherin 0.0012 0.002 0.002
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0045 0.0045
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0017 0.0045 0.0045
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0058 0.0483
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0099 0.0099
Schistosoma mansoni voltage-gated ion channel 0.0017 0.0045 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0003 0.0003
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0011 0.0079
Schistosoma mansoni carbonic anhydrase-related 0.0062 0.0288 0.0288
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Leishmania major glycerol uptake protein, putative 0.0182 0.0935 0.8632
Trypanosoma brucei kinesin, putative 0.002 0.0058 0.0442
Echinococcus granulosus serotonin receptor 0.0027 0.0099 0.0099
Echinococcus multilocularis roundabout 2 0.0036 0.0145 0.0145
Echinococcus granulosus tar DNA binding protein 0.0069 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0109
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0165 0.1471
Schistosoma mansoni slit 0.0012 0.002 0.002
Schistosoma mansoni hypothetical protein 0.011 0.0547 0.0547
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0017 0.0045 0.0357
Brugia malayi ecdysteroid receptor 0.0028 0.0101 0.0247
Schistosoma mansoni hypothetical protein 0.0143 0.0722 0.0722
Echinococcus granulosus protein kinase c epsilon type 0.0009 0.0003 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0045 0.0315
Leishmania major hypothetical protein, conserved 0.0029 0.0109 0.0953
Loa Loa (eye worm) Notch2 0.0012 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0051 0.0226 0.0226
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0045 0.0045
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Loa Loa (eye worm) notch protein 0.0012 0.002 0.0019
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0019
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0015 0.0036 0.0036
Entamoeba histolytica protein kinase , putative 0.021 0.1082 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0017 0.0045 0.0044
Brugia malayi G protein-coupled receptor 0.0027 0.0099 0.0241
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0017 0.0045 0.0045
Loa Loa (eye worm) DR-78 0.0013 0.0023 0.0023
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0058 0.0483
Echinococcus granulosus metabotropic glutamate receptor 5 0.0051 0.0229 0.0229
Onchocerca volvulus Matrilysin homolog 0.0078 0.0372 0.2271
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0087 0.0087
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0101 0.0247
Echinococcus granulosus GA binding protein alpha chain 0.0049 0.0217 0.0217
Schistosoma mansoni hypothetical protein 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Onchocerca volvulus 0.0012 0.002 0.0083
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0032 0.0127 0.108
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus multilocularis rho associated protein kinase 0.025 0.1297 0.1297
Trypanosoma brucei glycerol uptake protein, putative 0.0182 0.0935 0.8626
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.021 0.1082 1
Echinococcus multilocularis Immunoglobulin 0.0036 0.0145 0.0145
Brugia malayi hypothetical protein 0.001 0.0006 0.0016
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0099 0.0099
Schistosoma mansoni carbonic anhydrase-related 0.0062 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0009 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0011
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0017 0.0045 0.0357
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0093 0.0801
Brugia malayi Fli-1 protein 0.0149 0.0755 0.1842
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0109
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.003 0.003
Schistosoma mansoni adenoreceptor 0.0027 0.0099 0.0099
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0041 0.0175 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0935 0.8636
Toxoplasma gondii AGC kinase 0.0022 0.0071 0.0557
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Echinococcus multilocularis calcium activated potassium channel 0.002 0.0059 0.0059
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0182 0.0935 0.0935
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0045 0.0044
Brugia malayi Hr1 repeat family protein 0.0009 0.0003 0.0006
Leishmania major hypothetical protein, conserved 0.0019 0.0054 0.0438
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0009 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus mitogen activated protein kinase 0.0039 0.0165 0.0165
Brugia malayi nuclear hormone receptor family member odr-7 0.0013 0.0023 0.0056
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0144
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0044
Loa Loa (eye worm) AGC/NDR protein kinase 0.0009 0.0003 0.0002
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0325 0.0325
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0095 0.0463 0.4592
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0017 0.0045 0.0109
Brugia malayi Protein kinase domain containing protein 0.0011 0.0015 0.0035
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0017 0.0045 0.0109
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0182 0.0935 0.8636
Echinococcus granulosus histone acetyltransferase KAT2B 0.0032 0.0127 0.0127
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0099 0.0099
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0041 0.0176 0.0176
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0099 0.0099
Giardia lamblia Kinase, AGC PKA 0.0015 0.0036 0.0232
Loa Loa (eye worm) voltage-gated calcium channel 0.0017 0.0045 0.0044
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0109 0.0541 0.0541
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0143 0.0722 0.0722
Schistosoma mansoni hypothetical protein 0.0143 0.0722 0.0722
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0099 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0101 0.0247
Brugia malayi EGF-like domain containing protein 0.0012 0.002 0.0048
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0057 0.0432
Schistosoma mansoni hypothetical protein 0.027 0.1405 0.1405

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) Inhibition of human group 5 sPLA2 at 0.091 mol fraction after 30 mins ChEMBL. 20369880
Inhibition (binding) = 66 % Inhibition of human group 5A cPLA2 at 0.091 mol fraction after 30 mins by Dole assay ChEMBL. 20369880
Inhibition (binding) = 98.8 % Inhibition of human recombinant group 6A iPLA2 expressed in Sf9 insect cells at 0.091 mol fraction after 30 mins by Dole assay ChEMBL. 20369880
XI50 (binding) = 0.0013 mole fraction Inhibition of human recombinant group 6A iPLA2 expressed in Sf9 insect cells after 30 mins by Dole assay ChEMBL. 20369880

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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