Detailed information for compound 1241755

Basic information

Technical information
  • TDR Targets ID: 1241755
  • Name: (2S)-N-(2,4-dimethylphenyl)-1-[(3S)-1,2,3,4-t etrahydroisoquinoline-3-carbonyl]pyrrolidine- 2-carboxamide
  • MW: 377.479 | Formula: C23H27N3O2
  • H donors: 2 H acceptors: 2 LogP: 3.04 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H]1NCc2c(C1)cccc2
  • InChi: 1S/C23H27N3O2/c1-15-9-10-19(16(2)12-15)25-22(27)21-8-5-11-26(21)23(28)20-13-17-6-3-4-7-18(17)14-24-20/h3-4,6-7,9-10,12,20-21,24H,5,8,11,13-14H2,1-2H3,(H,25,27)/t20-,21-/m0/s1
  • InChiKey: RSJWOWVMKRUPFD-SFTDATJTSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-N-(2,4-dimethylphenyl)-1-[oxo-[(3S)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl]-2-pyrrolidinecarboxamide
  • (2S)-N-(2,4-dimethylphenyl)-1-[[(3S)-1,2,3,4-tetrahydroisoquinolin-3-yl]carbonyl]pyrrolidine-2-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0016 0.0139
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0103 0.1267
Brugia malayi Muscleblind-like protein 0.0317 0.1305 0.5625
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0026 0.0042
Chlamydia trachomatis lysine--tRNA ligase 0.0124 0.0481 0.7266
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0063 0.0272
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0121 0.0466 0.1129
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.017 0.0678 0.1017
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0272 0.1173
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0282 0.3577
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0098
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0087 0.0306
Treponema pallidum fructose-bisphosphate aldolase 0.0338 0.1394 1
Giardia lamblia Asparaginyl-tRNA synthetase 0.0019 0.0032 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0677 0.2919
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0166 0.0659 1
Treponema pallidum aspartyl-tRNA synthetase 0.0019 0.0032 0.019
Echinococcus multilocularis calcium dependent protein kinase 0.0159 0.0632 0.1531
Echinococcus granulosus pyruvate kinase 0.0019 0.0033 0.0117
Schistosoma mansoni threonyl-tRNA synthetase 0.0012 0.0005 0.0023
Echinococcus multilocularis pyruvate kinase 0.0037 0.011 0.0266
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0282 0.1296
Loa Loa (eye worm) hypothetical protein 0.0077 0.0282 0.1217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0016 0.0057
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0166 0.0659 0.2835
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0078 0.0285 0.4276
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.007 0.029
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Schistosoma mansoni smad 0.0012 0.0002 0.0008
Leishmania major pyruvate kinase 0.0037 0.011 0.1356
Giardia lamblia Thioredoxin reductase 0.0166 0.0659 0.2113
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0039 0.0034
Plasmodium falciparum asparagine--tRNA ligase 0.0019 0.0032 0.0026
Brugia malayi replication factor A 73 kDa subunit 0.0015 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0204 0.0821 0.3537
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0166 0.0659 0.2835
Schistosoma mansoni DNA polymerase IV / kappa 0.0013 0.0006 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Schistosoma mansoni glucose transport protein 0.0555 0.232 1
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0127 0.1573
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0105 0.0401 0.1877
Echinococcus multilocularis Smad4 0.0026 0.0063 0.0153
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0067 0.0288
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0015 0.0017 0.0042
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0241 0.0982 0.4232
Schistosoma mansoni Smad4 0.0026 0.0063 0.0272
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Plasmodium falciparum replication protein A1, large subunit 0.0015 0.0017 0.0012
Schistosoma mansoni smad1 5 8 and 0.0026 0.0063 0.0272
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0058
Entamoeba histolytica hypothetical protein 0.0075 0.0272 0.0863
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.017 0.0678 0.0672
Brugia malayi Transient-receptor-potential like protein 0.0121 0.0466 0.2011
Schistosoma mansoni lysyl-tRNA synthetase 0.0124 0.0481 0.2072
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.017 0.0677 0.2919
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0282 0.1296
Schistosoma mansoni pyruvate kinase 0.0019 0.0033 0.0143
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0026 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0686 0.2951
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0019 0.0032 0.035
Schistosoma mansoni hypothetical protein 0.0032 0.0087 0.0373
Loa Loa (eye worm) sugar transporter 0.0555 0.232 1
Echinococcus multilocularis pyruvate kinase 0.0037 0.011 0.0266
Schistosoma mansoni sugar transporter 0.0078 0.0285 0.1229
Loa Loa (eye worm) hypothetical protein 0.0117 0.045 0.1941
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0282 0.1207
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0166 0.0662 0.2347
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0027
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0019 0.0032 0.0404
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Echinococcus granulosus cpg binding protein 0.0032 0.009 0.032
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0016 0.0139
Trypanosoma cruzi seryl-tRNA synthetase 0.0012 0.0005 0.0004
Brugia malayi Aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0282 0.4233
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0026 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0066 0.0271
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.196 0.6947
Brugia malayi MH1 domain containing protein 0.0014 0.0014 0.0059
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0016 0.0068
Brugia malayi latrophilin 2 splice variant baaae 0.0326 0.1341 0.5783
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0139 0.0337
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0026 0.027
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.1 0.4312
Entamoeba histolytica Flap nuclease, putative 0.0025 0.006 0.0176
Brugia malayi major facilitator superfamily protein 0.0078 0.0285 0.1229
Brugia malayi hypothetical protein 0.0078 0.0285 0.1229
Schistosoma mansoni hypothetical protein 0.0047 0.0151 0.0651
Loa Loa (eye worm) hypothetical protein 0.0031 0.0085 0.0368
Trypanosoma brucei sugar transporter, putative 0.0078 0.0285 0.3613
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0127 0.0536
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0067 0.0797
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0127 0.1573
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Echinococcus multilocularis histidyl tRNA synthetase 0.0019 0.0032 0.0078
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0338 0.1394 0.4488
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.413 1
Echinococcus granulosus transient receptor potential ion channel A 0.0313 0.1289 0.4567
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0006 0.0018
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.006 0.0703
Brugia malayi Cam kinase protein 1 0.017 0.0677 0.2919
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0127 0.0307
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0362 0.156
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Echinococcus multilocularis transient receptor potential ion channel A 0.0313 0.1289 0.3121
Loa Loa (eye worm) hypothetical protein 0.003 0.0078 0.0337
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.007 0.0836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0103 0.0433
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0016 0.0068
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0016 0.0056
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0067 0.0061
Echinococcus multilocularis lamin 0.0061 0.0213 0.0517
Trichomonas vaginalis seryl-tRNA synthetase, putative 0.0012 0.0005 0.0012
Echinococcus multilocularis cpg binding protein 0.0032 0.009 0.0218
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.017 0.0678 0.0672
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.011 0.1356
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Brugia malayi hypothetical protein 0.0075 0.0272 0.1173
Echinococcus granulosus histidyl tRNA synthetase 0.0019 0.0032 0.0114
Echinococcus multilocularis pyruvate kinase 0.0019 0.0033 0.008
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.011 0.1438
Brugia malayi seryl-tRNA synthetase, mitochondrial precursor, putative 0.0012 0.0005 0.0023
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0063 0.0224
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0033 0.0046
Plasmodium falciparum mitogen-activated protein kinase 2 0.0897 0.3778 0.3774
Plasmodium falciparum proline--tRNA ligase 0.0194 0.078 0.0775
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Brugia malayi beta-lactamase family protein 0.0077 0.0282 0.1217
Echinococcus multilocularis solute carrier family 22 0.0078 0.0285 0.069
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0078 0.0285 0.069
Loa Loa (eye worm) hypothetical protein 0.0151 0.0595 0.2565
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0282 0.1296
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0151 0.0595 0.1441
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Schistosoma mansoni flap endonuclease-1 0.0023 0.0049 0.0212
Leishmania major seryl-tRNA synthetase, putative 0.0012 0.0005 0.0004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0172 0.0686 0.8791
Echinococcus granulosus solute carrier family 22 0.0078 0.0285 0.101
Schistosoma mansoni Smad4 0.0012 0.0002 0.0008
Echinococcus granulosus Smad4 0.0026 0.0063 0.0224
Brugia malayi polk-prov protein 0.0013 0.0006 0.0028
Brugia malayi MH1 domain containing protein 0.0026 0.0063 0.0273
Brugia malayi Disco-interacting protein 2 homolog 0.0037 0.0111 0.0478
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0115 0.0278
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0067 0.0797
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0127 0.1573
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0241 0.0982 0.2377
Schistosoma mansoni hypothetical protein 0.0351 0.1451 0.6254
Toxoplasma gondii ABC1 family protein 0.0077 0.0282 0.0421
Toxoplasma gondii anticodon binding domain-containing protein 0.0019 0.0032 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Toxoplasma gondii OB-fold nucleic acid binding domain-containing protein 0.0015 0.0017 0.0022
Mycobacterium ulcerans beta-lactamase 0.0077 0.0282 0.4233
Onchocerca volvulus 0.0078 0.0285 0.7647
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.011 0.2923
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0006 0.0018
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Plasmodium falciparum calcium-dependent protein kinase 1 0.017 0.0678 0.0672
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0282 0.1296
Schistosoma mansoni prolyl-tRNA synthetase 0.0012 0.0005 0.0023
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0019 0.0034 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0064 0.0266
Toxoplasma gondii aspartate-tRNA ligase 0.0019 0.0032 0.0044
Trypanosoma cruzi hexose transporter, putative 0.0172 0.0686 0.8791
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.017 0.0678 0.1017
Echinococcus granulosus disco interacting protein 2 0.0037 0.0111 0.0393
Echinococcus granulosus peregrin 0.0033 0.0094 0.0332
Brugia malayi beta-lactamase family protein 0.0077 0.0282 0.1217
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0062 0.0185
Plasmodium falciparum calcium-dependent protein kinase 3 0.017 0.0678 0.0672
Loa Loa (eye worm) hypothetical protein 0.0135 0.0529 0.2281
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0063 0.0224
Loa Loa (eye worm) transcription factor SMAD2 0.0382 0.1583 0.6824
Plasmodium falciparum pyruvate kinase 0.0037 0.011 0.0105
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0098
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0031 0.0085 0.0368
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0103 0.1267
Schistosoma mansoni hypothetical protein 0.0096 0.0362 0.1559
Trichomonas vaginalis sugar transporter, putative 0.0172 0.0686 0.2951
Echinococcus granulosus mothers against decapentaplegic 2 0.0012 0.0002 0.0006
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0006 0.0018
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0019 0.0032 0.0113
Echinococcus multilocularis solute carrier family 22 0.0078 0.0285 0.069
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0078 0.0285 0.131
Giardia lamblia Lysyl-tRNA synthetase 0.0124 0.0481 0.1536
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0142 0.0612
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0015 0.0017 0.0074
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0098
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0142 0.1765
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0073 0.0873
Onchocerca volvulus 0.0078 0.0285 0.7647
Loa Loa (eye worm) hypothetical protein 0.0037 0.0111 0.0478
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0115 0.0495
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0019 0.0032 0.0077
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0166 0.0659 0.2835
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Toxoplasma gondii sugar transporter ST2 0.0078 0.0285 0.0425
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0127 0.0536
Onchocerca volvulus 0.0078 0.0285 0.7647
Echinococcus multilocularis peregrin 0.0033 0.0094 0.0227
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0282 0.3577
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0087 0.0081
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0031 0.0335
Schistosoma mansoni DNA polymerase eta 0.0041 0.0127 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Giardia lamblia Aspartyl-tRNA synthetase 0.0019 0.0032 0.0085
Echinococcus granulosus DNA methyltransferase 2, putative 0.0019 0.0034 0.0119
Plasmodium vivax asparagine--tRNA ligase, putative 0.0019 0.0032 0.0026
Entamoeba histolytica seryl-tRNA synthetase, putative 0.0012 0.0005 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0282 0.1217
Treponema pallidum thioredoxin reductase (trxB) 0.0166 0.0659 0.4709
Onchocerca volvulus 0.0096 0.0362 0.9719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0016 0.0057
Loa Loa (eye worm) hypothetical protein 0.0041 0.0127 0.0547
Schistosoma mansoni hypothetical protein 0.0555 0.232 1
Toxoplasma gondii transporter, major facilitator family protein 0.0078 0.0285 0.0425
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0555 0.232 0.822
Echinococcus multilocularis solute carrier family 22 0.0078 0.0285 0.069
Chlamydia trachomatis aspartate--tRNA(Asp/Asn) ligase 0.0019 0.0032 0.0404
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0282 0.1296
Giardia lamblia Hypothetical protein 0.0015 0.0017 0.0039
Onchocerca volvulus 0.0078 0.0285 0.7647
Toxoplasma gondii tRNA ligase class II core domain (G, H, P, S and T) domain-containing protein 0.0012 0.0005 0.0004
Leishmania major hypothetical protein, conserved 0.0077 0.0282 0.3577
Loa Loa (eye worm) hypothetical protein 0.0326 0.1341 0.5782
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0127 0.0547
Onchocerca volvulus 0.0078 0.0285 0.7647
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0127 0.0307
Echinococcus multilocularis SPRY domain containing protein 0.0017 0.0023 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0285 0.1219
Echinococcus multilocularis transient receptor potential gamma protein 0.0324 0.1335 0.3232
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.011 0.2923
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Echinococcus multilocularis 0.0017 0.0023 0.0055
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.011 0.0475
Giardia lamblia DNA repair protein RAD52 0.0738 0.31 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0555 0.232 0.822
Brugia malayi MH2 domain containing protein 0.0382 0.1583 0.6824
Echinococcus granulosus intermediate filament protein 0.0061 0.0213 0.0756
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Chlamydia trachomatis histidine--tRNA ligase 0.0019 0.0032 0.041
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Leishmania major pyruvate kinase 0.0037 0.011 0.1356
Echinococcus granulosus flap endonuclease 1 0.0025 0.006 0.0211
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Brugia malayi Sugar transporter family protein 0.0555 0.232 1
Brugia malayi jmjC domain containing protein 0.0103 0.0392 0.1691
Brugia malayi Calcitonin receptor-like protein seb-1 0.0476 0.1984 0.8554
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0124 0.0481 0.7266
Mycobacterium tuberculosis Conserved protein 0.0077 0.0282 0.1296
Trypanosoma brucei seryl-tRNA synthetase 0.0012 0.0005 0.0004
Trichomonas vaginalis glucose transporter, putative 0.0172 0.0686 0.2951
Loa Loa (eye worm) hypothetical protein 0.0077 0.0282 0.1217
Leishmania major DNA polymerase kappa, putative 0.0013 0.0006 0.0018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0282 0.1
Brugia malayi Latrophilin receptor protein 2 0.0151 0.0595 0.2566
Echinococcus granulosus prolyl tRNA synthetase mitochondrial 0.0012 0.0005 0.0019
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0031 0.0085 0.0207
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Schistosoma mansoni histidyl-tRNA synthetase 0.0019 0.0032 0.0138
Loa Loa (eye worm) hypothetical protein 0.0032 0.0087 0.0373
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0016 0.0139
Brugia malayi hypothetical protein 0.0067 0.0238 0.1028
Echinococcus granulosus solute carrier family 22 0.0078 0.0285 0.101
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0016 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trypanosoma brucei unspecified product 0.0041 0.0127 0.1573
Plasmodium vivax sugar transporter, putative 0.0078 0.0285 0.028
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0555 0.232 0.5617
Leishmania major protein kinase, putative 0.017 0.0677 0.8671
Entamoeba histolytica hypothetical protein 0.0075 0.0272 0.0863
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0395 0.5036
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0017 0.0023 0.0098
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0555 0.232 0.5617
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0019 0.0032 0.0077
Schistosoma mansoni transient receptor potential channel 0.0214 0.0867 0.3736
Brugia malayi isocitrate dehydrogenase 0.0017 0.0026 0.0112
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0031 0.0085 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0601
Brugia malayi CXXC zinc finger family protein 0.0032 0.009 0.0389
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0067 0.0288
Echinococcus granulosus dna polymerase eta 0.0041 0.0127 0.045
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.1639
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0033 0.0028
Giardia lamblia Pyruvate kinase 0.0019 0.0033 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0241 0.0982 0.4232
Brugia malayi beta-lactamase 0.0077 0.0282 0.1217
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trypanosoma brucei pyruvate kinase 1 0.0037 0.011 0.1356
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.007 0.0257
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0897 0.3778 0.5687
Trypanosoma cruzi DNA polymerase eta, putative 0.0013 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0124 0.0481 0.2072
Brugia malayi MH2 domain containing protein 0.0012 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trichomonas vaginalis CAMK family protein kinase 0.017 0.0677 0.2911
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0092 0.0397
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0151 0.0595 0.2109
Echinococcus multilocularis 0.0017 0.0023 0.0055
Leishmania major DNA repair and recombination protein RAD54, putative 0.0017 0.0023 0.023
Echinococcus multilocularis lamin dm0 0.0061 0.0213 0.0517
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0031 0.0085 0.1223
Onchocerca volvulus 0.0078 0.0285 0.7647
Loa Loa (eye worm) hypothetical protein 0.0054 0.0183 0.0787
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0018 0.0024
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0062 0.0268
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0268
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0115 0.0407
Echinococcus multilocularis synaptic vesicle 2 protein 0.0078 0.0285 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0331
Brugia malayi mothers against decapentaplegic homolog 3 0.0012 0.0002 0.0008
Echinococcus multilocularis tumor protein p63 0.0673 0.2822 0.6833
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0031 0.0085 0.1223
Plasmodium vivax DNA repair protein REV1, putative 0.0013 0.0006 0.0001
Leishmania major threonyl-tRNA synthetase, putative 0.0031 0.0085 0.1036
Onchocerca volvulus 0.0078 0.0285 0.7647
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0142 0.0611
Trypanosoma cruzi histidyl-tRNA synthetase 0.0019 0.0032 0.035
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0151 0.0595 0.1441
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0555 0.232 0.5617
Giardia lamblia DINP protein human, muc B family 0.0041 0.0127 0.0393
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0063 0.0272
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0055 0.0224
Leishmania major lysyl-tRNA synthetase, putative 0.0124 0.0481 0.6136
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0063 0.0272
Plasmodium falciparum calcium-dependent protein kinase 5 0.017 0.0678 0.0672
Loa Loa (eye worm) hypothetical protein 0.0476 0.1984 0.8554
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0142 0.1765
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Loa Loa (eye worm) RecQ helicase 0.0023 0.0051 0.022
Mycobacterium ulcerans integral membrane transport protein 0.0078 0.0285 0.4276
Trichomonas vaginalis sugar transporter, putative 0.0172 0.0686 0.2951
Schistosoma mansoni cpg binding protein 0.0032 0.009 0.0389
Entamoeba histolytica hypothetical protein 0.0124 0.0481 0.1536
Echinococcus granulosus lamin 0.0061 0.0213 0.0756
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0059 0.0203 0.3022
Trypanosoma brucei Replication factor A protein 1 0.0015 0.0017 0.0158
Schistosoma mansoni protein kinase 0.017 0.0677 0.2919
Brugia malayi Major Facilitator Superfamily protein 0.0078 0.0285 0.1229
Plasmodium falciparum DNA repair and recombination protein RAD54, putative 0.0017 0.0023 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0006 0.0018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0241 0.0982 0.2377
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Schistosoma mansoni cpg binding protein 0.0032 0.009 0.0389
Schistosoma mansoni histidyl-tRNA synthetase 0.0019 0.0032 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0003 0.0002
Schistosoma mansoni Smad4 0.0012 0.0002 0.0008
Trypanosoma cruzi glucose transporter, putative 0.0078 0.0285 0.3613
Loa Loa (eye worm) major facilitator superfamily transporter 0.0078 0.0285 0.1229
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0028 0.007 0.0836
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Trypanosoma brucei DNA repair and recombination protein RAD54, putative 0.0017 0.0023 0.023
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0031 0.0085 0.1036
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0142 0.0611
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0067 0.0288
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0017 0.0023 0.0098
Leishmania major glycyl tRNA synthetase, putative 0.0019 0.0032 0.035
Leishmania major hypothetical protein, conserved 0.0028 0.007 0.0836
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0282 0.0683
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0165 0.0657 0.3128
Entamoeba histolytica DNA repair protein, putative 0.0017 0.0023 0.0058
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0027 0.0067 0.0199
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.011 0.0475
Entamoeba histolytica hypothetical protein 0.0075 0.0272 0.0863
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0019 0.0032 0.0077
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.003 0.013
Trypanosoma cruzi sugar transporter, putative 0.0078 0.0285 0.3613
Echinococcus multilocularis muscleblind protein 0.0317 0.1305 0.316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0224
Leishmania major replication Factor A 28 kDa subunit, putative 0.0015 0.0017 0.0158
Echinococcus granulosus lysyl tRNA synthetase 0.0124 0.0481 0.1703
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0555 0.232 0.822
Brugia malayi MH1 domain containing protein 0.0026 0.0063 0.0273
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.011 0.0464
Giardia lamblia PHD finger protein 15 0.0032 0.0087 0.0262
Trichomonas vaginalis esterase, putative 0.0077 0.0282 0.1207
Schistosoma mansoni lamin 0.0061 0.0213 0.092
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0087 0.0209
Echinococcus multilocularis mothers against decapentaplegic 2 0.0012 0.0002 0.0004
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.1639
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0316
Loa Loa (eye worm) pyruvate kinase 0.0037 0.011 0.0474
Loa Loa (eye worm) hypothetical protein 0.006 0.0209 0.0899
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Plasmodium vivax aspartate--tRNA ligase, putative 0.0019 0.0032 0.0026
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.017 0.0677 0.2399
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0078 0.0285 0.131
Plasmodium vivax lysine--tRNA ligase, putative 0.0124 0.0481 0.0475
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0127 0.1573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0103 0.0433
Schistosoma mansoni hypothetical protein 0.0151 0.0595 0.2565
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0127 0.0536
Echinococcus multilocularis dna repair and recombination protein rad54 0.0017 0.0023 0.0055
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0034 0.0092
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.006 0.0256
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0392 0.139
Loa Loa (eye worm) nuclear factor I 0.0014 0.0014 0.0058
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.0067 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Leishmania major asparaginyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0087 0.0126
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.0019 0.0032 0.0404
Mycobacterium leprae Probable lipase LipE 0.0077 0.0282 0.4107
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0026 0.0021
Leishmania major DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Giardia lamblia Prolyl-tRNA synthetase 0.0166 0.0662 0.2123
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0019 0.0034 0.0028
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0082 0.0301 0.0296
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0241 0.0982 0.3478
Toxoplasma gondii DNA methyltransferase 2, putative 0.0019 0.0034 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0006 0.0018
Echinococcus multilocularis calcium activated potassium channel 0.0021 0.0044 0.0105
Loa Loa (eye worm) sugar transporter 0.0078 0.0285 0.1229
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0031 0.0085 0.0368
Brugia malayi hypothetical protein 0.0078 0.0285 0.1229
Toxoplasma gondii seryl-tRNA synthetase, cytoplasmic, putative 0.0012 0.0005 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0601
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0028 0.007 0.0836
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0166 0.0662 0.2124
Echinococcus multilocularis Seryl tRNA Synthetase 0.0012 0.0005 0.0013
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0019 0.0034 0.0144
Schistosoma mansoni seryl-tRNA synthetase 0.0012 0.0005 0.0023
Onchocerca volvulus 0.0098 0.0372 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0055 0.0224
Schistosoma mansoni threonyl-tRNA synthetase 0.0019 0.0032 0.0138
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0115 0.0495
Echinococcus multilocularis pyruvate kinase 0.0019 0.0033 0.008
Trichomonas vaginalis sugar transporter, putative 0.0172 0.0686 0.2951
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0067 0.0097
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.011 0.2923
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0034 0.0028
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0395 0.039
Loa Loa (eye worm) hypothetical protein 0.0104 0.0395 0.1704
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0166 0.0662 0.1604
Onchocerca volvulus 0.0077 0.0282 0.7572
Plasmodium vivax calcium-dependent protein kinase, putative 0.017 0.0678 0.0672
Loa Loa (eye worm) major facilitator superfamily transporter 0.0078 0.0285 0.1229
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0015 0.0017 0.0063
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0015 0.0017 0.0158
Loa Loa (eye worm) hypothetical protein 0.0037 0.011 0.0474
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0555 0.232 0.822
Loa Loa (eye worm) hypothetical protein 0.0317 0.1305 0.5625
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Echinococcus granulosus pyruvate kinase 0.0037 0.011 0.039
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0194 0.078 1
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Onchocerca volvulus 0.0077 0.0282 0.7572
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.011 0.0454
Schistosoma mansoni transient receptor potential channel 0.0324 0.1335 0.5754
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0026 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0224
Giardia lamblia Glycyl-tRNA synthetase 0.0031 0.0085 0.0258
Echinococcus multilocularis pyruvate kinase 0.0029 0.0077 0.0186
Plasmodium falciparum phd finger protein, putative 0.0032 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0008
Giardia lamblia TCP-1 chaperonin subunit beta 0.0027 0.0067 0.0198
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0897 0.3778 0.3774
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0031 0.0085 0.1036
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0019 0.0032 0.0138
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0338 0.1394 0.4488
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Echinococcus granulosus solute carrier family 22 0.0078 0.0285 0.101
Giardia lamblia Pyruvate kinase 0.0037 0.011 0.0338
Brugia malayi Sars1 protein 0.0012 0.0005 0.0023
Trypanosoma cruzi hexose transporter, putative 0.0078 0.0285 0.3613
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0015 0.0017 0.0061
Leishmania major hypothetical protein, conserved 0.0104 0.0395 0.5036
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0051 0.0124
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0019 0.0032 0.0044
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0165 0.0657 0.991
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0114 0.0481
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0067 0.0236
Echinococcus multilocularis musashi 0.0061 0.0213 0.0517
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0051 0.0221
Plasmodium falciparum calcium-dependent protein kinase 2 0.017 0.0678 0.0672
Mycobacterium ulcerans lipase LipD 0.0077 0.0282 0.4233
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0272 0.0964
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0282 0.1207
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0105 0.0401 0.1877
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0019 0.0032 0.0113
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0087
Entamoeba histolytica protein kinase, putative 0.017 0.0677 0.2171
Loa Loa (eye worm) MH1 domain-containing protein 0.0012 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0316
Brugia malayi follicle stimulating hormone receptor 0.0246 0.1 0.4312
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0127 0.1573
Trypanosoma cruzi hexose transporter, putative 0.0094 0.0354 0.4496
Plasmodium falciparum DNA repair protein REV1, putative 0.0013 0.0006 0.0001
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0063 0.0153
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0165 0.0657 0.9957
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0026 0.027
Echinococcus multilocularis geminin 0.0351 0.1451 0.3513
Plasmodium falciparum protein kinase 7 0.1568 0.6641 0.6639
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0016 0.0057
Loa Loa (eye worm) latrophilin receptor protein 2 0.0151 0.0595 0.2565
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Trichomonas vaginalis sugar transport protein, putative 0.0078 0.0285 0.1219
Leishmania major glucose transporter, lmgt2 0.0172 0.0686 0.8791
Treponema pallidum prolyl-tRNA synthetase 0.0059 0.0203 0.1423
Schistosoma mansoni smad1 5 8 and 0.0026 0.0063 0.0272
Leishmania major hypothetical protein, conserved 0.0028 0.007 0.0836
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0031 0.0085 0.0357
Echinococcus granulosus glycyl tRNA synthetase 0.0031 0.0085 0.0302
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0016 0.0068
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0142 0.1765
Giardia lamblia DNA damage repair protein 0.0013 0.0006 0.0003
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0017 0.0023 0.023
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0006 0.0018
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0166 0.0662 0.2856
Loa Loa (eye worm) Sars1 protein 0.0012 0.0005 0.0023
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0213 0.092
Treponema pallidum threonyl-tRNA synthetase 0.0031 0.0085 0.0576
Trichomonas vaginalis glucose transporter, putative 0.0078 0.0285 0.1219
Echinococcus multilocularis prolyl tRNA synthetase, mitochondrial 0.0012 0.0005 0.0013
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0067 0.0797
Loa Loa (eye worm) type III restriction enzyme 0.0017 0.0023 0.0098
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0166 0.0659 0.9954
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0103 0.0433
Onchocerca volvulus 0.0078 0.0285 0.7647
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0282 0.1207
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0166 0.0662 0.2856
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0087 0.0126
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0031 0.0085 0.1036
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0031 0.0085 0.0125
Toxoplasma gondii lysine-tRNA ligase 0.0124 0.0481 0.072
Mycobacterium ulcerans pyruvate kinase 0.0037 0.011 0.1601
Echinococcus granulosus short transient receptor potential channel 6 0.0214 0.0867 0.3071
Schistosoma mansoni sugar transporter 0.0078 0.0285 0.1229
Schistosoma mansoni seryl-tRNA synthetase 0.0012 0.0005 0.0023
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0067 0.0061
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0124 0.0481 0.7182
Plasmodium falciparum flap endonuclease 1 0.0025 0.006 0.0054
Brugia malayi MH2 domain containing protein 0.0026 0.0063 0.0273
Schistosoma mansoni glycyl-tRNA synthetase 0.0031 0.0085 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Echinococcus granulosus dna polymerase kappa 0.0041 0.0127 0.045
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0031 0.0085 0.026
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.006 0.0703
Loa Loa (eye worm) seryl-tRNA synthetase 0.0012 0.0005 0.0023
Plasmodium falciparum nucleic acid binding protein, putative 0.0015 0.0017 0.0012
Brugia malayi Sugar transporter family protein 0.0078 0.0285 0.1229
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0019 0.0032 0.035
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0213 0.092
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0031 0.0085 0.1223
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0019 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0006 0.0006
Echinococcus granulosus pyruvate kinase 0.0019 0.0033 0.0117
Leishmania major DNA polymerase eta, putative 0.0013 0.0006 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0103 0.0433
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0026 0.0112
Schistosoma mansoni helicase 0.0065 0.0229 0.0987
Plasmodium falciparum asparagine--tRNA ligase 0.0019 0.0032 0.0026
Echinococcus granulosus SPRY domain containing protein 0.0017 0.0023 0.0081
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0016 0.0038
Brugia malayi BRM protein 0.0065 0.0229 0.0988
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0302 0.1301
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0395 0.5036
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.0395 0.0592
Loa Loa (eye worm) MH2 domain-containing protein 0.0012 0.0002 0.0008
Echinococcus granulosus GPCR family 2 0.0151 0.0595 0.2109
Plasmodium falciparum hexose transporter 0.0555 0.232 0.2315
Mycobacterium tuberculosis Conserved protein 0.0077 0.0282 0.1296
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0142 0.1765
Plasmodium vivax CDK-related protein kinase 6, putative 0.2355 1 1
Echinococcus granulosus bloom syndrome protein 0.0023 0.0051 0.0181
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0078 0.0285 0.3613
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0476 0.1984 0.8554
Schistosoma mansoni pyruvate kinase 0.0037 0.011 0.0474
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.017 0.0677 0.2919
Echinococcus multilocularis solute carrier family 22 0.0078 0.0285 0.069
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0166 0.0659 1
Entamoeba histolytica seryl-tRNA synthetase, putative 0.0012 0.0005 0.0001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0006 0.0006
Chlamydia trachomatis pyruvate kinase 0.0037 0.011 0.1601
Mycobacterium leprae conserved hypothetical protein 0.0028 0.007 0.0815
Loa Loa (eye worm) beta-lactamase 0.0077 0.0282 0.1217
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0075 0.0314
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0282 0.1296
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0093 0.0136
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0031 0.0085 0.0333
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0124 0.0481 0.6136
Onchocerca volvulus 0.0078 0.0285 0.7647
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0166 0.0662 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0142 0.0343
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0092 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0285 0.1219
Schistosoma mansoni lamin 0.0061 0.0213 0.092
Leishmania major lysyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0028 0.007 0.0101
Onchocerca volvulus 0.0078 0.0285 0.7647
Leishmania major aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0127 0.0547
Loa Loa (eye worm) pyruvate kinase 0.0037 0.011 0.0474
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trypanosoma brucei unspecified product 0.0028 0.0073 0.0873
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0241 0.0982 0.4232
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0051 0.0209
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0015 0.0017 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0016 0.0057
Chlamydia trachomatis proline--tRNA ligase 0.0059 0.0203 0.3022
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0016 0.0139
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0078 0.0277
Echinococcus granulosus tumor protein p63 0.0673 0.2822 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.1639
Schistosoma mansoni smad1 5 8 and 0.0026 0.0063 0.0272
Loa Loa (eye worm) hypothetical protein 0.0166 0.0662 0.2856
Echinococcus granulosus Sugar transporter ERD6 protein 0.0078 0.0285 0.101
Echinococcus granulosus solute carrier family 22 0.0078 0.0285 0.101
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0127 0.1573
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0078 0.0285 0.4276
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.011 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0686 0.2951
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0092
Loa Loa (eye worm) hypothetical protein 0.0166 0.0662 0.2856
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0272 0.0659
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0282 0.1207
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0124 0.0481 0.7266
Schistosoma mansoni protein kinase 0.017 0.0677 0.2919
Schistosoma mansoni protein kinase 0.017 0.0677 0.2919
Echinococcus multilocularis dna repair and recombination protein rad54 0.0017 0.0023 0.0055
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0127 0.1859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0064 0.0266
Loa Loa (eye worm) hypothetical protein 0.011 0.042 0.1812
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0098
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0142 0.0442
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0282 0.1207
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.007 0.029
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0127 0.0547
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0127 0.0536
Onchocerca volvulus 0.0037 0.0111 0.2946
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0017 0.0023 0.0099
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0282 0.1217
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0015 0.0017 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0282 0.4233
Schistosoma mansoni pyruvate kinase 0.0037 0.011 0.0474
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.017 0.0677 0.8671
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0067 0.0288
Toxoplasma gondii serine--tRNA ligase 0.0012 0.0005 0.0004
Onchocerca volvulus 0.0078 0.0285 0.7647
Loa Loa (eye worm) 63kd antigen 0.0019 0.0032 0.0137
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0194 0.078 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0016 0.0139
Leishmania major replication factor A, 51kDa subunit, putative 0.0015 0.0017 0.0158
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.092
Echinococcus granulosus Seryl tRNA Synthetase 0.0012 0.0005 0.0019
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.2399
Chlamydia trachomatis thioredoxin reductase 0.0166 0.0659 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trypanosoma cruzi hexose transporter, putative 0.0172 0.0686 0.8791
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0282 0.0277
Echinococcus granulosus lamin dm0 0.0061 0.0213 0.0756
Toxoplasma gondii sugar transporter ST1 0.0078 0.0285 0.0425
Plasmodium falciparum lysine--tRNA ligase 0.0124 0.0481 0.0475
Echinococcus multilocularis seryl tRNA synthetase, mitochondrial 0.0012 0.0005 0.0013
Giardia lamblia Sugar-proton symporter 0.0078 0.0285 0.0904
Loa Loa (eye worm) BRM protein 0.0034 0.0095 0.0411
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.006 0.0245
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0392 0.095
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.0151 0.0365
Leishmania major hypothetical protein, conserved 0.0078 0.0285 0.3613
Schistosoma mansoni sugar transporter 0.0078 0.0285 0.1229
Onchocerca volvulus Alhambra homolog 0.0032 0.0087 0.2288
Plasmodium vivax pyruvate kinase, putative 0.0037 0.011 0.0105
Brugia malayi hypothetical protein 0.0078 0.0285 0.1229
Onchocerca volvulus 0.0077 0.0282 0.7572
Schistosoma mansoni hypothetical protein 0.0151 0.0595 0.2565
Schistosoma mansoni hypothetical protein 0.0326 0.1341 0.5782
Schistosoma mansoni hypothetical protein 0.0151 0.0595 0.2565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0055 0.0224
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0142 0.1765
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0026 0.0035
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0051 0.0209
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0015 0.0017 0.0158
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0124 0.0481 0.6136
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0019 0.0032 0.041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0282 0.1217
Echinococcus multilocularis short transient receptor potential channel 6 0.0214 0.0867 0.2099
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Plasmodium vivax glycine--tRNA ligase, putative 0.0031 0.0085 0.008
Leishmania major glucose transporter/membrane transporter D2, putative 0.0172 0.0686 0.8791
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0241 0.0982 0.4232
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0194 0.078 1
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0127 0.0547
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0019 0.0032 0.041
Brugia malayi Major Facilitator Superfamily protein 0.0078 0.0285 0.1229
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0005 0.001
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0019 0.0032 0.0126
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0019 0.0032 0.0127
Entamoeba histolytica DNA repair protein, putative 0.0017 0.0023 0.0058
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0194 0.078 0.1171
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0006 0.0018
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0015 0.0017 0.0012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0078 0.0189
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Onchocerca volvulus 0.0078 0.0285 0.7647
Schistosoma mansoni cpg binding protein 0.0032 0.009 0.0389
Leishmania major glucose transporter, lmgt3 0.0172 0.0686 0.8791
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0115 0.0495
Brugia malayi Smad1 0.0026 0.0063 0.0273
Trypanosoma brucei glucose transporter, putative 0.0172 0.0686 0.8791
Plasmodium vivax hexose transporter 0.0555 0.232 0.2315
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.017 0.0678 0.1017
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0372 0.1604
Echinococcus granulosus pyruvate kinase 0.0019 0.0033 0.0117
Echinococcus granulosus dna repair and recombination protein rad54 0.0017 0.0023 0.0081
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0015 0.0017 0.0418
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0127 0.045
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0194 0.078 1
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0015 0.0017 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0073 0.0873
Toxoplasma gondii facilitative glucose transporter GT1 0.0555 0.232 0.349
Echinococcus granulosus TRP transient receptor potential channel 0.0121 0.0466 0.1653
Mycobacterium ulcerans hypothetical protein 0.0013 0.0006 0.0016
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0028 0.007 0.0836
Schistosoma mansoni sugar transporter 0.0078 0.0285 0.1229
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0282 0.4107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.2399
Loa Loa (eye worm) hypothetical protein 0.0324 0.1335 0.5754
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0285 0.1219
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Echinococcus multilocularis global transcription activator snf2l2 0.0065 0.0229 0.0554
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0019 0.0034 0.0081
Loa Loa (eye worm) hypothetical protein 0.0077 0.0282 0.1217
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0151 0.0595 0.2109
Leishmania major modification methylase-like protein 0.0019 0.0034 0.0368
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0017 0.0158
Echinococcus multilocularis smad 0.0026 0.0063 0.0153
Mycobacterium tuberculosis Conserved protein 0.0077 0.0282 0.1296
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.011 0.0162
Schistosoma mansoni intermediate filament proteins 0.0061 0.0213 0.092
Brugia malayi Sugar transporter family protein 0.0078 0.0285 0.1229
Mycobacterium ulcerans hypothetical protein 0.0028 0.007 0.0986
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0139 0.0493
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0166 0.0662 0.2848
Onchocerca volvulus 0.0032 0.009 0.2388
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0078 0.0285 0.028
Mycobacterium ulcerans hypothetical protein 0.0077 0.0282 0.4233
Echinococcus granulosus mothers against decapentaplegic 6 0.0012 0.0002 0.0006
Brugia malayi Flap endonuclease-1 0.0025 0.006 0.0257
Loa Loa (eye worm) BRM protein 0.0041 0.0129 0.0556
Trichomonas vaginalis seryl-tRNA synthetase, putative 0.0012 0.0005 0.0012
Onchocerca volvulus 0.0078 0.0285 0.7647
Echinococcus granulosus synaptic vesicle 2 protein 0.0078 0.0285 0.101
Trypanosoma cruzi hexose transporter, putative 0.0172 0.0686 0.8791
Echinococcus granulosus short transient receptor potential channel 6 0.0214 0.0867 0.3071
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0031 0.0085 0.026
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0151 0.0595 0.2566
Trypanosoma cruzi hexose transporter 0.0172 0.0686 0.8791
Schistosoma mansoni aspartyl-tRNA synthetase 0.0015 0.0017 0.0074
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0078 0.0285 0.4276
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Toxoplasma gondii glycyl-tRNA synthetase 0.0031 0.0085 0.0125
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0042 0.0475
Leishmania major histidyl-tRNA synthetase, putative 0.0019 0.0032 0.035
Giardia lamblia Fructose-bisphosphate aldolase 0.0338 0.1394 0.4488
Brugia malayi Associated with TFs and helicases family protein 0.0011 0 0.0001
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0067 0.0161
Plasmodium vivax asparagine--tRNA ligase, putative 0.0019 0.0032 0.0026
Loa Loa (eye worm) Smad1 0.0026 0.0063 0.0272
Plasmodium vivax replication protein A1, large subunit, putative 0.0015 0.0017 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0241 0.0982 0.3478
Toxoplasma gondii sugar transporter ST3 0.0078 0.0285 0.0425
Echinococcus multilocularis disco interacting protein 2 0.0037 0.0111 0.0268
Echinococcus multilocularis short transient receptor potential channel 6 0.0214 0.0867 0.2099
Echinococcus granulosus calcium dependent protein kinase 0.0159 0.0632 0.224
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.006 0.0703
Leishmania major glucose transporter, lmgt1 0.0172 0.0686 0.8791
Loa Loa (eye worm) pyruvate kinase 0.0037 0.011 0.0474
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0282 0.1217
Echinococcus granulosus Threonyl tRNA synthetase C 0.0031 0.0085 0.0302
Trypanosoma brucei chrX additional, unordered contigs 0.0013 0.0006 0.0018
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0103 0.1267
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0017 0.0023 0.023
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0285 0.1219
Plasmodium falciparum glycine--tRNA ligase 0.0019 0.0032 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Trypanosoma brucei histidyl-tRNA synthetase 0.0019 0.0032 0.035
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.021 0.0848 0.2723
Brugia malayi hypothetical protein 0.0104 0.0395 0.1705
Onchocerca volvulus 0.0078 0.0285 0.7647
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Echinococcus granulosus global transcription activator snf2l2 0.0065 0.0229 0.0811
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Echinococcus multilocularis SPRY domain containing protein 0.0017 0.0023 0.0055
Echinococcus multilocularis mothers against decapentaplegic 6 0.0012 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0282 0.3577
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0063 0.0153
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0026 0.0112
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0074
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0019 0.0032 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0006 0.0018
Echinococcus granulosus pyruvate kinase 0.0037 0.011 0.039
Plasmodium vivax histidine--tRNA ligase, putative 0.0019 0.0032 0.0027
Schistosoma mansoni peptidase 0.0014 0.0012 0.0053
Leishmania major myo-inositol/proton symporter (MIT) 0.0078 0.0285 0.3613
Echinococcus multilocularis GPCR, family 2 0.0151 0.0595 0.1441
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0066 0.0271
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0006 0.0006
Echinococcus granulosus SPRY domain containing protein 0.0017 0.0023 0.0081
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0026 0.0063
Leishmania major DNA damage repair protein, putative 0.0013 0.0006 0.0018
Onchocerca volvulus 0.0061 0.0213 0.5712
Trypanosoma brucei unspecified product 0.0028 0.0073 0.0873
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.0395 0.5036
Chlamydia trachomatis threonine--tRNA ligase 0.0031 0.0085 0.1223
Echinococcus granulosus DNA repair and recombination protein RAD54B 0.0017 0.0023 0.0081
Schistosoma mansoni lysyl-tRNA synthetase 0.0124 0.0481 0.2072
Echinococcus granulosus calcium activated potassium channel 0.0021 0.0044 0.0154
Brugia malayi Major Facilitator Superfamily protein 0.0078 0.0285 0.1229
Entamoeba histolytica hypothetical protein 0.021 0.0848 0.2723
Onchocerca volvulus 0.0078 0.0285 0.7647
Brugia malayi Bromodomain containing protein 0.0033 0.0094 0.0405
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Schistosoma mansoni glucose transporter 0.0078 0.0285 0.1229
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0026 0.0035
Brugia malayi recombination factor GdRad54 0.0017 0.0023 0.0099
Entamoeba histolytica hypothetical protein 0.0015 0.0017 0.004
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0019 0.0032 0.0137
Brugia malayi PHD-finger family protein 0.0032 0.0087 0.0373
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0087 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0063
Schistosoma mansoni glucose transport protein 0.0555 0.232 1
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.196 0.4747
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0037 0.0111 0.0478
Brugia malayi jmjC domain containing protein 0.0038 0.0115 0.0495
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0031 0.0085 0.1055
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0142 0.1765
Schistosoma mansoni smad 0.0026 0.0063 0.0272
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0166 0.0662 0.2856
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.006 0.0175
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0127 0.0394
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0067 0.0288
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0087 0.0373
Toxoplasma gondii protein kinase, putative 0.1568 0.6641 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.007 0.029
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0395 0.039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Loa Loa (eye worm) hypothetical protein 0.0471 0.196 0.8452
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0166 0.0659 0.2835
Echinococcus multilocularis dna polymerase eta 0.0041 0.0127 0.0307
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.2399
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0033 0.0028
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0555 0.232 0.5617
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.011 0.1356
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0494 0.2061 1
Echinococcus multilocularis flap endonuclease 1 0.0025 0.006 0.0144
Giardia lamblia Threonyl-tRNA synthetase 0.0031 0.0085 0.0258
Onchocerca volvulus 0.0078 0.0285 0.7647
Trypanosoma cruzi Replication factor A protein 1 0.0015 0.0017 0.0158
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.017 0.0678 0.0672
Echinococcus granulosus smad 0.0026 0.0063 0.0224
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0063
Trypanosoma brucei glucose transporter 2A 0.0172 0.0686 0.8791
Schistosoma mansoni aspartyl-tRNA synthetase 0.0019 0.0032 0.0137
Entamoeba histolytica protein kinase, putative 0.017 0.0677 0.2171
Schistosoma mansoni hypothetical protein 0.0151 0.0595 0.2565
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.0151 0.0535
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.006 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0601
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0282 0.1296
Treponema pallidum asparaginyl-tRNA synthetase 0.0019 0.0032 0.019
Giardia lamblia Hexose transporter 0.0078 0.0285 0.0904
Schistosoma mansoni glucose transport protein 0.0555 0.232 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0241 0.0982 0.4232
Loa Loa (eye worm) hypothetical protein 0.0098 0.0372 0.1604
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0166 0.0662 0.2856
Echinococcus granulosus transient receptor potential gamma protein 0.0324 0.1335 0.473
Schistosoma mansoni survival motor neuron protein 0.0096 0.0362 0.1559
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Plasmodium vivax proline--tRNA ligase, putative 0.0194 0.078 0.0775
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0127 0.0547
Echinococcus multilocularis pyruvate kinase 0.0019 0.0033 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0103 0.0433
Mycobacterium ulcerans sugar transporter 0.0078 0.0285 0.4276
Echinococcus multilocularis dna repair and recombination protein rad54 0.0017 0.0023 0.0055
Plasmodium vivax threonine--tRNA ligase, putative 0.0031 0.0085 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0066 0.0271
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0124 0.0481 0.2063
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Loa Loa (eye worm) hypothetical protein 0.0077 0.0282 0.1217
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Giardia lamblia GTOR 0.0044 0.0142 0.0441
Leishmania major aspartyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.009 0.0389
Schistosoma mansoni hypothetical protein 0.0075 0.0272 0.1173
Trypanosoma brucei THT1 - hexose transporter, putative 0.0172 0.0686 0.8791
Plasmodium falciparum aspartate--tRNA ligase 0.0019 0.0032 0.0026
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0078 0.0285 0.1229
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.017 0.0677 0.1639
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0166 0.0659 0.3142
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Echinococcus multilocularis lysyl tRNA synthetase 0.0124 0.0481 0.1164
Brugia malayi intermediate filament protein 0.0061 0.0213 0.092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Echinococcus granulosus SPRY domain containing protein 0.0017 0.0023 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0555 0.232 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0031 0.0085 0.1036
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0019 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0224
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0338 0.1394 0.6006
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0109 0.0415 0.1782
Entamoeba histolytica hypothetical protein 0.0075 0.0272 0.0863
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0026 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0073 0.0873
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0019 0.0032 0.0077
Leishmania major DNA polymerase eta, putative 0.0041 0.0127 0.1573
Brugia malayi glycyl-tRNA synthetase 0.0031 0.0085 0.0368
Entamoeba histolytica thioredoxin reductase, putative 0.0166 0.0659 0.2114
Onchocerca volvulus 0.0061 0.0213 0.5712
Brugia malayi major facilitator superfamily protein 0.0078 0.0285 0.1229
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.006 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.023 0.099
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Plasmodium vivax DNA repair protein RAD54, putative 0.0017 0.0023 0.0018
Trichomonas vaginalis glucose transporter, putative 0.0172 0.0686 0.2951
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0476 0.1984 0.8554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0016 0.0057
Trichomonas vaginalis myo-inositol transporter, putative 0.0078 0.0285 0.1219
Loa Loa (eye worm) MH2 domain-containing protein 0.0382 0.1583 0.6824
Loa Loa (eye worm) hypothetical protein 0.0317 0.1305 0.5625
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0055 0.0224
Trypanosoma brucei glucose transporter 1E 0.0172 0.0686 0.8791
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0012 0.0005 0.0012
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0105 0.0401 0.5947
Echinococcus multilocularis General substrate transporter 0.0477 0.1987 0.4811
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0026 0.0112
Schistosoma mansoni transient receptor potential channel 0.0214 0.0867 0.3736
Brugia malayi MH1 domain containing protein 0.0014 0.0014 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0031 0.0085 0.0368
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0019 0.0032 0.0346
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.007 0.0836
Plasmodium falciparum threonine--tRNA ligase 0.0031 0.0085 0.008
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0194 0.078 1
Onchocerca volvulus Putative transporter 0.0078 0.0285 0.7647
Trichomonas vaginalis chaperonin, putative 0.0027 0.0067 0.0277
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0068 0.0244 0.105
Trypanosoma brucei THT1 - hexose transporter, putative 0.0172 0.0686 0.8791
Echinococcus granulosus General substrate transporter 0.0477 0.1987 0.704
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0019 0.0032 0.0113
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.0395 0.039
Trypanosoma cruzi replication Factor A 28 kDa subunit, putative 0.0015 0.0017 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Schistosoma mansoni hypothetical protein 0.0351 0.1451 0.6254
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0031 0.0085 0.1223
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Treponema pallidum glycyl-tRNA synthetase 0.0019 0.0032 0.0193
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0142 0.0442
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Loa Loa (eye worm) hypothetical protein 0.017 0.0677 0.2919
Echinococcus granulosus seryl tRNA synthetase mitochondrial 0.0012 0.0005 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0285 0.1219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0285 0.1219
Echinococcus multilocularis glycyl tRNA synthetase 0.0031 0.0085 0.0207
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0166 0.0659 0.2835
Loa Loa (eye worm) hypothetical protein 0.0077 0.0282 0.1217
Loa Loa (eye worm) hypothetical protein 0.0121 0.0466 0.201
Echinococcus granulosus muscleblind protein 0.0317 0.1305 0.4624
Plasmodium falciparum calcium-dependent protein kinase 4 0.017 0.0678 0.0672
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0142 0.0502
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Loa Loa (eye worm) hypothetical protein 0.0077 0.0282 0.1217
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.011 0.1356
Echinococcus multilocularis muscleblind protein 1 0.0317 0.1305 0.316
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0127 0.1573
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0019 0.0032 0.0088
Brugia malayi lysyl-tRNA synthetase 0.0124 0.0481 0.2072
Brugia malayi hypothetical protein 0.0471 0.196 0.8452
Loa Loa (eye worm) hypothetical protein 0.0078 0.0285 0.1229
Toxoplasma gondii hypothetical protein 0.0082 0.0301 0.0449
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0067 0.0288
Brugia malayi MH2 domain containing protein 0.0026 0.0063 0.0273
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0738 0.31 1
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0213 0.092
Echinococcus granulosus geminin 0.0351 0.1451 0.5141
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0006 0.0018
Plasmodium falciparum histidine--tRNA ligase, putative 0.0019 0.0032 0.0027
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0026 0.027
Schistosoma mansoni transient receptor potential channel 4 0.0324 0.1335 0.5754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0391
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0019 0.0034 0.0047
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.017 0.0677 0.2919
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0127 0.1859
Schistosoma mansoni replication factor A 1 rfa1 0.0015 0.0017 0.0074

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 8.1961 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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