Detailed information for compound 1251811

Basic information

Technical information
  • TDR Targets ID: 1251811
  • Name: [(2S)-2-acetyloxypropyl]-trimethylazanium
  • MW: 160.234 | Formula: C8H18NO2+
  • H donors: 0 H acceptors: 1 LogP: 0.6 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](C[N+](C)(C)C)OC(=O)C
  • InChi: 1S/C8H18NO2/c1-7(11-8(2)10)6-9(3,4)5/h7H,6H2,1-5H3/q+1/t7-/m0/s1
  • InChiKey: NZWOPGCLSHLLPA-ZETCQYMHSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [(2S)-2-acetoxypropyl]-trimethyl-ammonium
  • [(2S)-2-acetoxypropyl]-trimethylammonium
  • [(2S)-2-acetyloxypropyl]-trimethyl-azanium
  • CAS-62-51-1
  • NCGC00016282-01
  • Lopac-A-2251
  • NCGC00015045-01
  • ZINC03831050

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Muscarinic acetylcholine receptor M1 Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Bacillus anthracis Anthrax lethal factor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis serotonin receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Schistosoma mansoni amine GPCR Muscarinic acetylcholine receptor M1   460 aa 463 aa 27.0 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Muscarinic acetylcholine receptor M1   460 aa 462 aa 23.4 %
Loa Loa (eye worm) hypothetical protein Muscarinic acetylcholine receptor M1   460 aa 425 aa 22.1 %
Echinococcus granulosus biogenic amine 5HT receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0276
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0164 0.0151
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0043 0.0167 0.0311
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0177
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0597 0.148
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0043 0.0167 0.0402
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0149 0.0267
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.012 0.022
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0733 0.1417
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus granulosus dna polymerase kappa 0.0044 0.0174 0.0409
Onchocerca volvulus 0.0043 0.0167 0.0242
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0013 0.0009
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.0174 0.0162
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus multilocularis G-protein coupled receptor, putative 0.0043 0.0167 0.0154
Echinococcus multilocularis expressed protein 0.0451 0.2399 0.2389
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Echinococcus multilocularis G protein coupled receptor 139 0.0043 0.0167 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Echinococcus multilocularis g-protein coupled receptor 0.0043 0.0167 0.0154
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.006
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.0107 0.0239
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 1
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0948 0.5122 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0174 0.0227
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Echinococcus granulosus cpg binding protein 0.0034 0.0121 0.0273
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0015
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0303 0.0577
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0164 0.0467
Brugia malayi hypothetical protein 0.002 0.0044 0.0071
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0948 0.5122 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0174 0.0325
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0586 0.1131
Echinococcus granulosus axis inhibition protein axin 0.0023 0.006 0.0119
Echinococcus granulosus tachykinin peptides receptor 99D 0.0043 0.0167 0.039
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Loa Loa (eye worm) cytochrome P450 0.0015 0.0013 0.0009
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0167 0.0311
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Echinococcus granulosus sex peptide receptor 0.0043 0.0167 0.039
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Onchocerca volvulus 0.0287 0.1502 0.2871
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0164 0.0205
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0043 0.0167 0.0154
Brugia malayi regulator of G-protein signaling egl-10 0.0032 0.0107 0.0194
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.006 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0174 0.05
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0149 0.0267
Schistosoma mansoni hypothetical protein 0.0146 0.0733 0.1833
Mycobacterium ulcerans beta-lactamase 0.004 0.0149 0.0276
Leishmania major DNA polymerase eta, putative 0.0044 0.0174 0.05
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0013 0.0009
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0167 0.0402
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0948 0.5122 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0149 0.0137
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0167 0.0154
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0219 0.0524
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.006 0.0101
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.0107 0.0094
Onchocerca volvulus 0.0032 0.0111 0.0131
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0267
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0174 0.0325
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.006 0.0047
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0379 0.2007 0.3909
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0379 0.2007 0.6002
Schistosoma mansoni nardilysin (M16 family) 0.0078 0.0357 0.0884
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.0107 0.0094
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.006 0.0119
Echinococcus multilocularis transient receptor potential gamma protein 0.0105 0.0505 0.0493
Echinococcus granulosus RUN 0.002 0.0044 0.0079
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0164 0.0304
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0043 0.0167 0.0154
Schistosoma mansoni regulator of G protein signaling 0.0032 0.0107 0.0251
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0303 0.0735
Brugia malayi Dopamine receptor protein 1 0.0043 0.0167 0.0311
Onchocerca volvulus 0.004 0.0149 0.0207
Schistosoma mansoni transient receptor potential channel 0.0069 0.0311 0.0768
Echinococcus granulosus axis inhibition protein axin 0.0023 0.006 0.0119
Echinococcus multilocularis transcription factor btf3 0.0038 0.0139 0.0127
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.006 0.0119
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0164 0.0304
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.0052 0.0219 0.0414
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.006 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0149 0.0276
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0219 0.0524
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0044 0.0031
Brugia malayi hypothetical protein 0.0016 0.002 0.0023
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0028 0.006
Onchocerca volvulus 0.0037 0.0134 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Echinococcus granulosus fmrfamide receptor 0.0043 0.0167 0.039
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.0174 0.0421
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0164 0.0382
Brugia malayi putative neuropeptide receptor NPR1 0.0043 0.0167 0.0311
Brugia malayi Serotonin receptor 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1502 0.2849
Echinococcus granulosus serotonin receptor 0.0043 0.0167 0.039
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0167 0.039
Toxoplasma gondii toxolysin TLN4 0.0034 0.0121 0.0341
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0174 0.0162
Onchocerca volvulus Neuropeptide F receptor homolog 0.0043 0.0167 0.0242
Schistosoma mansoni lipoxygenase 0.0121 0.0597 0.1491
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0028 0.006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0043 0.0167 0.039
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0622 0.3338 1
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0167 0.0311
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0219 0.0207
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis nardilysin 0.0047 0.019 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0164 0.0205
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0586 0.1131
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0219 0.0414
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0358
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0067 0.0178
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0013 0.0009
Schistosoma mansoni cytochrome P450 0.0015 0.0013 0.0012
Schistosoma mansoni axis inhibition protein axin 0.0023 0.006 0.0131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Schistosoma mansoni opsin-like receptor 0.0043 0.0167 0.0402
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.0178
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0208 0.0195
Toxoplasma gondii peptidase M16 inactive domain-containing protein 0.0047 0.019 0.0546
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0134 0.0319
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0062 0.0163
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0622 0.3338 0.8424
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0155 0.0373
Echinococcus granulosus 7tm_1 domain containing protein 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni biogenic amine receptor 0.0043 0.0167 0.0402
Brugia malayi Pax transcription factor protein 2 0.05 0.2669 0.5203
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0174 0.0325
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0259 0.0491
Schistosoma mansoni transcription factor btf3 0.0038 0.0139 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Loa Loa (eye worm) insulin-degrading enzyme 0.0078 0.0357 0.0684
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0149 0.0276
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0317 0.0781
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0044 0.0132
Schistosoma mansoni cpg binding protein 0.0032 0.0111 0.026
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0043 0.0167 0.0402
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.0174 0.0409
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0319
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0149 0.0276
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0028 0.0015
Brugia malayi jmjC domain containing protein 0.0103 0.0496 0.0954
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Echinococcus granulosus biogenic amine 5HT receptor 0.0043 0.0167 0.039
Schistosoma mansoni transient receptor potential channel 0.0069 0.0311 0.0768
Echinococcus granulosus allatostatin A receptor 0.0043 0.0167 0.039
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0067 0.0201
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0051 0.0084
Echinococcus multilocularis short transient receptor potential channel 6 0.0069 0.0311 0.0299
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0164 0.0394
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0043 0.0167 0.039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0319
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.0174 0.0325
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0319
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni histamine h1 receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0031 0.0105 0.019
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0174 0.05
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0105 0.0245
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0013 0.0009
Echinococcus multilocularis somatostatin receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0496 0.0484
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0116
Brugia malayi N-terminal motif family protein 0.0176 0.0894 0.1733
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0149 0.0267
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0062 0.0106
Echinococcus multilocularis neuropeptide s receptor 0.0043 0.0167 0.0154
Echinococcus granulosus short transient receptor potential channel 6 0.0069 0.0311 0.0757
Onchocerca volvulus 0.0043 0.0167 0.0242
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0164 0.0467
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0043 0.0167 0.0311
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.006 0.0131
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0044 0.0079
Loa Loa (eye worm) hypothetical protein 0.0054 0.0228 0.043
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0028 0.006
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0259 0.0624
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.0174 0.0316
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.0139 0.0394
Leishmania major basic transcription factor 3a, putative 0.0038 0.0139 0.0394
Brugia malayi putative neuropeptide receptor 0.0043 0.0167 0.0311
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus multilocularis nardilysin 0.0078 0.0357 0.0345
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0043 0.0167 0.0311
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0208 0.0391
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0177
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni myosin xvIII 0.0043 0.0167 0.0402
Echinococcus granulosus dna polymerase eta 0.0044 0.0174 0.0409
Echinococcus granulosus orexin receptor type 2 0.0043 0.0167 0.039
Onchocerca volvulus 0.0043 0.0167 0.0242
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.0139 0.0394
Trypanosoma brucei unspecified product 0.003 0.0099 0.0275
Brugia malayi G protein-coupled receptor 0.0043 0.0167 0.0311
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0013 0.0014
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0105 0.019
Echinococcus multilocularis RUN 0.002 0.0044 0.0031
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0167 0.0154
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0043 0.0167 0.0311
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0105 0.0291
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.006 0.0119
Schistosoma mansoni alpha-1 adrenergic receptor 0.0043 0.0167 0.0402
Schistosoma mansoni hypothetical protein 0.0031 0.0105 0.0245
Schistosoma mansoni transient receptor potential channel 4 0.0105 0.0505 0.1258
Brugia malayi MH2 domain containing protein 0.0119 0.0586 0.1131
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus multilocularis insulin degrading enzyme 0.0078 0.0357 0.0345
Brugia malayi Cytochrome P450 family protein 0.0024 0.0062 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.006 0.0131
Schistosoma mansoni neuropeptide f receptor 76f 0.0043 0.0167 0.0402
Brugia malayi hypothetical protein 0.002 0.0044 0.0071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi G-protein coupled receptor 0.0043 0.0167 0.0311
Brugia malayi CXXC zinc finger family protein 0.0032 0.0111 0.0201
Trichomonas vaginalis esterase, putative 0.004 0.0149 0.0177
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0277 0.0807
Echinococcus granulosus g-protein coupled receptor 0.0043 0.0167 0.039
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0167 0.0154
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0219 0.0535
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0134 0.0122
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1315 0.2548
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.006 0.0131
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.006 0.0131
Toxoplasma gondii hypothetical protein 0.0031 0.0101 0.0278
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0013 0.0009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0167 0.0402
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0167 0.0154
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Trypanosoma brucei C-8 sterol isomerase, putative 0.0379 0.2007 0.6002
Echinococcus granulosus 3'partial|nardilysin 0.0078 0.0357 0.0873
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0043 0.0167 0.0402
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0013 0.0014
Chlamydia trachomatis insulinase family protease III 0.0078 0.0357 0.5
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Toxoplasma gondii NAC domain-containing protein 0.0038 0.0139 0.0394
Schistosoma mansoni transient receptor potential channel 0.0105 0.0505 0.1258
Giardia lamblia DINP protein human, muc B family 0.0044 0.0174 0.0325
Leishmania major phosphoglycan beta 1,3 galactosyltransferase 5 0.0078 0.0357 0.105
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.006 0.0119
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0043 0.0167 0.0402
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.1062 0.1051
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Echinococcus granulosus alpha 1A adrenergic receptor 0.0043 0.0167 0.039
Echinococcus multilocularis sex peptide receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Mycobacterium leprae conserved hypothetical protein 0.004 0.0149 1
Brugia malayi neuropeptide F receptor 0.0043 0.0167 0.0311
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0167 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0388 0.2058 0.3948
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0028 0.0039
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0141 0.0128
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0043 0.0167 0.0242
Echinococcus granulosus neuropeptide FF receptor 2 0.0043 0.0167 0.039
Schistosoma mansoni biogenic amine receptor 0.0043 0.0167 0.0402
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0015
Brugia malayi G-protein coupled receptor 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0172 0.016
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0167 0.039
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0259 0.0624
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus granulosus 7TM GPCR rhodopsin 0.0043 0.0167 0.039
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0043 0.0167 0.0311
Brugia malayi ORL1-like opioid receptor 0.0043 0.0167 0.0311
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0134 0.0307
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0043 0.0167 0.0402
Onchocerca volvulus Alhambra homolog 0.0031 0.0105 0.012
Brugia malayi hypothetical protein 0.0023 0.006 0.0101
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.1312 0.255
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0259 0.0247
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0013 0.0009
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0164 0.0151
Loa Loa (eye worm) RGS-3 protein 0.0023 0.006 0.0101
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0167 0.0154
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0622 0.3338 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0028 0.0084
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0013 0.0009
Brugia malayi AKH receptor 0.0043 0.0167 0.0311
Brugia malayi follicle stimulating hormone receptor 0.0321 0.1687 0.3283
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0303 0.0291
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.039
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0146 0.0133
Loa Loa (eye worm) hypothetical protein 0.0543 0.2902 0.566
Brugia malayi sulfakinin receptor protein 0.0043 0.0167 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Echinococcus granulosus GPCR family 2 0.0068 0.0303 0.0735
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0149 0.0267
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.0154
Brugia malayi Cytochrome P450 family protein 0.0015 0.0013 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0303 0.0291
Loa Loa (eye worm) hypothetical protein 0.0379 0.2007 0.3909
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.0178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0167 0.0402
Brugia malayi Serotonin receptor 0.0043 0.0167 0.0311
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0174 0.05
Schistosoma mansoni hypothetical protein 0.0318 0.1675 0.4215
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0067 0.0201
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0167 0.0154
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0105 0.0092
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0043 0.0167 0.0154
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0167 0.039
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.006 0.0101
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0134 0.0379
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0303 0.0577
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0167 0.039
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0167 0.0402
Onchocerca volvulus 0.004 0.0149 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0948 0.5122 1
Brugia malayi hypothetical protein 0.0023 0.006 0.0101
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0134 0.0122
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis short transient receptor potential channel 6 0.0069 0.0311 0.0299
Leishmania major cytochrome p450-like protein 0.0015 0.0013 0.0014
Trypanosoma brucei transcription factor BTF3, putative 0.0038 0.0139 0.0394
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Onchocerca volvulus 0.0043 0.0167 0.0242
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0041 0.0155 0.0373
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0043 0.0167 0.0402
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0177
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.039
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0013 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Echinococcus granulosus peregrin 0.0031 0.0105 0.0233
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0288 0.0548
Schistosoma mansoni rab6-interacting 0.002 0.0044 0.0091
Echinococcus granulosus neuropeptide receptor 0.0043 0.0167 0.039
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0062 0.0106
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0622 0.3338 1
Plasmodium vivax SET domain protein, putative 0.0037 0.0134 0.0402
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) ICD-1 protein 0.0038 0.0139 0.0257
Echinococcus multilocularis transient receptor potential ion channel A 0.0101 0.0486 0.0474
Schistosoma mansoni DNA polymerase eta 0.0044 0.0174 0.0421
Echinococcus multilocularis cpg binding protein 0.0034 0.0121 0.0108
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0167 0.0402
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0123 0.0279
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0028 0.003
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0259 0.0247
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0208 0.0494
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi PHD-finger family protein 0.0031 0.0105 0.019
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0167 0.0154
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0043 0.0167 0.0402
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0562 0.3007 0.5864
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.006 0.0047
Brugia malayi Cytochrome P450 family protein 0.0034 0.012 0.022
Onchocerca volvulus 0.0043 0.0167 0.0242
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.0424
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0149 0.0267
Leishmania major cytochrome p450-like protein 0.0024 0.0062 0.0163
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0151 0.0362
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0151 0.0362
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0044 0.0031
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0276
Schistosoma mansoni loxhd1 0.002 0.0044 0.0091
Brugia malayi beta-lactamase 0.004 0.0149 0.0276
Loa Loa (eye worm) hypothetical protein 0.0044 0.0174 0.0325
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0358
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0267
Echinococcus multilocularis dro:myosuppressin receptor 0.0043 0.0167 0.0154
Trypanosoma brucei unspecified product 0.0044 0.0174 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0139 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0139 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Schistosoma mansoni opsin-like receptor 0.0043 0.0167 0.0402
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0013 0.0009
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0062 0.0163
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Toxoplasma gondii rhoptry metalloprotease toxolysin TLN1 0.0078 0.0357 0.105
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0176 0.0894 0.1733
Echinococcus granulosus insulin degrading enzyme 0.0078 0.0357 0.0873
Loa Loa (eye worm) hypothetical protein 0.0146 0.0733 0.1417
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0622 0.3338 0.333
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0543 0.2902 0.566
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0177
Schistosoma mansoni z-protein (S1r protein) 0.0032 0.0107 0.0251
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0164 0.0151
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0164 0.0382
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0105 0.0291
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Brugia malayi neuropeptide F receptor 0.0043 0.0167 0.0311
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0134 0.0247
Brugia malayi Pre-SET motif family protein 0.0037 0.0134 0.0247
Toxoplasma gondii ABC1 family protein 0.004 0.0149 0.0424
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0043 0.0167 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus granulosus expressed protein 0.0451 0.2399 0.6043
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trypanosoma brucei unspecified product 0.003 0.0099 0.0275
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0948 0.5122 1
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.0107 0.0239
Echinococcus granulosus biogenic amine 5HT receptor 0.0285 0.149 0.3742
Brugia malayi Melatonin receptor type 1A 0.0043 0.0167 0.0311
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0167 0.0154
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0167 0.0402
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0067 0.0178
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0062 0.0163
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0172 0.0404
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0208 0.0195
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0948 0.5122 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0174 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0149 0.0276
Onchocerca volvulus 0.0043 0.0167 0.0242
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.006 0.0101
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Schistosoma mansoni lipoxygenase 0.0085 0.0397 0.0985
Echinococcus granulosus geminin 0.0736 0.3962 1
Onchocerca volvulus 0.05 0.2669 0.5169
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0167 0.039
Echinococcus multilocularis geminin 0.0736 0.3962 0.3954
Echinococcus granulosus g protein coupled receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0015
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0044 0.0031
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) hypothetical protein 0.0105 0.0505 0.0972
Toxoplasma gondii sporozoite developmental protein 0.0078 0.0357 0.105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni cpg binding protein 0.0034 0.0121 0.0285
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0043 0.0167 0.0154
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0044 0.0132
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0219 0.0535
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Echinococcus granulosus g protein coupled receptor 0.0043 0.0167 0.039
Echinococcus multilocularis nardilysin 0.0078 0.0357 0.0345
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0208 0.0505
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0149 0.0424
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0562 0.3007 0.5864
Loa Loa (eye worm) hypothetical protein 0.0285 0.149 0.2899
Onchocerca volvulus 0.0043 0.0167 0.0242
Loa Loa (eye worm) hypothetical protein 0.0066 0.0292 0.0556
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0013 0.0014
Echinococcus granulosus G protein coupled receptor 139 0.0043 0.0167 0.039
Leishmania major cytochrome p450-like protein 0.0015 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Brugia malayi larval opioid receptor 0.0043 0.0167 0.0311
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0597 0.0585
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0099 0.0275
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0948 0.5122 1
Schistosoma mansoni hypothetical protein 0.0736 0.3962 1
Loa Loa (eye worm) hypothetical protein 0.0194 0.0993 0.1926
Brugia malayi Pre-SET motif family protein 0.0252 0.1312 0.255
Entamoeba histolytica transcription factor BTF3, putative 0.0038 0.0139 0.0157
Brugia malayi mbt repeat family protein 0.0052 0.0219 0.0414
Brugia malayi insulin-degrading enzyme 0.0078 0.0357 0.0684
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0177
Brugia malayi PXA domain containing protein 0.0023 0.006 0.0101
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.0174 0.0421
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0167 0.039
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0164 0.0467
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0208 0.0391
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0167 0.0154
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0013 0.0014
Echinococcus granulosus transient receptor potential ion channel A 0.0101 0.0486 0.1199
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Echinococcus granulosus short transient receptor potential channel 6 0.0069 0.0311 0.0757
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0028 0.006
Brugia malayi RE15519p 0.0043 0.0167 0.0311
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.0424
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0948 0.5122 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0013 0.0009
Echinococcus multilocularis serotonin receptor 0.0285 0.149 0.148
Brugia malayi G protein-coupled receptor F59B2.13 0.0043 0.0167 0.0311
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0208 0.0505
Brugia malayi Cytochrome P450 family protein 0.0024 0.0062 0.0106
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Echinococcus multilocularis allatostatin A receptor 0.0043 0.0167 0.0154
Loa Loa (eye worm) pax transcription factor protein 2 0.05 0.2669 0.5203
Mycobacterium ulcerans hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) hypothetical protein 0.0032 0.0107 0.0194
Schistosoma mansoni nardilysin (M16 family) 0.0078 0.0357 0.0884
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Plasmodium falciparum DNA repair protein REV1, putative 0.0014 0.0008 0.0024
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0043 0.0167 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0139 0.0157
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0164 0.0382
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0622 0.3338 1
Schistosoma mansoni insulysin (M16 family) 0.0043 0.0169 0.0407
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0303 0.0577
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0071
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0174 0.05
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0013 0.0009
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0167 0.0154
Schistosoma mansoni growth hormone secretagogue receptor 0.0043 0.0167 0.0402
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.006 0.0047
Toxoplasma gondii insulysin, putative 0.0074 0.0337 0.0987
Mycobacterium leprae Probable lipase LipE 0.004 0.0149 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Loa Loa (eye worm) doublecortin family protein 0.002 0.0044 0.0071
Echinococcus granulosus neuropeptide receptor A26 0.0043 0.0167 0.039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0164 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0948 0.5122 1
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0174 0.0325
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0013 0.0009
Echinococcus granulosus peptide allatostatin:somatostatin 0.0043 0.0167 0.039
Schistosoma mansoni rab6-interacting 0.002 0.0044 0.0091
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0149 0.0346
Plasmodium falciparum phd finger protein, putative 0.0031 0.0105 0.0314
Brugia malayi Bromodomain containing protein 0.0031 0.0105 0.019
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0622 0.3338 0.8422
Echinococcus multilocularis neuropeptide FF receptor 2 0.0043 0.0167 0.0154
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0013 0.0009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0155 0.0143
Loa Loa (eye worm) TYRA-2 protein 0.0043 0.0167 0.0311
Brugia malayi beta-NAC-like protein 0.0038 0.0139 0.0257
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.0174 0.05
Schistosoma mansoni adenoreceptor 0.0043 0.0167 0.0402
Brugia malayi hypothetical protein 0.0025 0.0067 0.0116
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0028 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0167 0.039
Plasmodium vivax hypothetical protein, conserved 0.004 0.0149 0.0447
Brugia malayi PXA domain containing protein 0.0023 0.006 0.0101
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.1103 0.2141
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0948 0.5122 1
Echinococcus granulosus somatostatin receptor 0.0043 0.0167 0.039
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0149 0.0267
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0041 0.0083
Brugia malayi isocitrate dehydrogenase 0.0017 0.0028 0.0039
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.006 0.0047
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0151 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0099 0.0275
Echinococcus multilocularis GPCR, family 2 0.0068 0.0303 0.0291
Onchocerca volvulus 0.0948 0.5122 1
Brugia malayi hypothetical protein 0.0041 0.0155 0.0288
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0219 0.0346
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0149 0.0267
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0146 0.0337
Leishmania major C-8 sterol isomerase-like protein 0.0379 0.2007 0.6002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0303 0.0577
Onchocerca volvulus Glucosylceramidase homolog 0.0369 0.195 0.3753
Echinococcus multilocularis neuropeptide receptor A26 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0259 0.0635
Mycobacterium ulcerans lipase LipD 0.004 0.0149 0.0276
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0151 0.028
Onchocerca volvulus 0.0052 0.0219 0.0346
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0062 0.0106
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni biogenic amine (5HT) receptor 0.0285 0.149 0.375
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0948 0.5122 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0043 0.0167 0.0154
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.1103 0.2141
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0622 0.3338 1
Loa Loa (eye worm) hypothetical protein 0.0285 0.149 0.2899
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus granulosus nardilysin 0.0078 0.0357 0.0873
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni hypothetical protein 0.002 0.0044 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.1103 0.2141
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0038
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.006 0.0131
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.1062 0.2657
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0219 0.0207
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Trypanosoma brucei peptidase, putative 0.0078 0.0357 0.105
Echinococcus granulosus g protein coupled receptor 0.0043 0.0167 0.039
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0013 0.0009
Onchocerca volvulus 0.0043 0.0167 0.0242
Loa Loa (eye worm) beta-lactamase 0.004 0.0149 0.0276
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0208 0.0494
Brugia malayi Doublecortin family protein 0.002 0.0044 0.0071
Loa Loa (eye worm) MBCTL1 0.006 0.0259 0.0491
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0208 0.0505
Leishmania major DNA polymerase kappa, putative 0.0044 0.0174 0.05
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0099 0.0275
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.0174 0.0227
Onchocerca volvulus 0.0043 0.0167 0.0242
Trypanosoma cruzi peptidase, putative 0.0078 0.0357 0.105
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.006 0.0047
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0013 0.0009
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0078 0.0357 0.0884
Echinococcus multilocularis orexin receptor type 2 0.0043 0.0167 0.0154
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.006 0.0101
Giardia lamblia PHD finger protein 15 0.0031 0.0105 0.019
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0028 0.0084
Onchocerca volvulus 0.004 0.0149 0.0207
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0496 0.1224
Plasmodium falciparum basic transcription factor 3b, putative 0.0038 0.0139 0.0417
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0032 0.0107 0.0194
Echinococcus granulosus hypothetical protein 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0214 0.1103 0.2141
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0028 0.0039
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0219 0.0535
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0044 0.0079
Leishmania major hypothetical protein, conserved 0.0025 0.0067 0.0178
Schistosoma mansoni polycystin 1-related 0.002 0.0044 0.0091
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0012
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0013 0.0009
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0164 0.0205
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0174 0.05
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Brugia malayi jmjC domain containing protein 0.004 0.0151 0.028
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.006 0.0101
Schistosoma mansoni hypothetical protein 0.0736 0.3962 1
Echinococcus multilocularis serotonin receptor 0.0285 0.149 0.148
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.006 0.0047
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0622 0.3338 0.6477
Schistosoma mansoni family M16 unassigned peptidase (M16 family) 0.0031 0.0101 0.0235
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0167 0.0154
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0105 0.0233
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0303 0.0735
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0111 0.0201
Leishmania major hypothetical protein, conserved 0.004 0.0149 0.0424
Schistosoma mansoni biogenic amine (5HT) receptor 0.0043 0.0167 0.0402
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0155 0.0361
Echinococcus granulosus dro:myosuppressin receptor 0.0043 0.0167 0.039
Plasmodium vivax basic transcription factor 3b, putative 0.0038 0.0139 0.0417
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0388 0.2058 0.3948
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0013 0.0009
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0105 0.0314
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0028 0.0015
Schistosoma mansoni axis inhibition protein axin 0.0023 0.006 0.0131
Echinococcus granulosus neuropeptide s receptor 0.0043 0.0167 0.039
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0146 0.027
Schistosoma mansoni biogenic amine receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0042 0.0164 0.0304
Echinococcus multilocularis dna polymerase eta 0.0044 0.0174 0.0162
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Echinococcus granulosus 5'partial|nardilysin 0.0034 0.0121 0.0275
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus granulosus neuropeptide receptor 0.0043 0.0167 0.039
Brugia malayi Dopamine receptor 0.0043 0.0167 0.0311
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.0894 0.1675
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.006 0.0259 0.0491
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.006 0.0119
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0078 0.0357 0.0884
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0948 0.5122 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0146 0.027
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0948 0.5122 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0174 0.0316
Schistosoma mansoni opsin-like receptor 0.0043 0.0167 0.0402
Brugia malayi Dopamine receptor protein 2 0.0043 0.0167 0.0311
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0067 0.0201
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 0.6477
Brugia malayi GnHR receptor homolog 0.0043 0.0167 0.0311
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0044 0.0079
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0164 0.0467
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0062 0.0106
Brugia malayi Tachykinin-like peptides receptor 99D 0.0043 0.0167 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Trypanosoma cruzi peptidase, putative 0.0078 0.0357 0.105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0232
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0043 0.0167 0.0311
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.006
Echinococcus multilocularis peregrin 0.0031 0.0105 0.0092
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0164 0.0394
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus granulosus transient receptor potential gamma protein 0.0105 0.0505 0.1247
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0321 0.1687 0.3283
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 0.6477
Schistosoma mansoni jumonji domain containing protein 0.0082 0.038 0.0942
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.006 0.0047
Entamoeba histolytica hypothetical protein 0.0038 0.0139 0.0157
Brugia malayi mbt repeat family protein 0.0052 0.0219 0.0414
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0043 0.0167 0.0311
Schistosoma mansoni cpg binding protein 0.0034 0.0121 0.0285
Loa Loa (eye worm) melatonin receptor type 1A 0.0043 0.0167 0.0311
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0267
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus granulosus transcription factor btf3 0.0038 0.0139 0.032
Brugia malayi cytochrome P450 0.0015 0.0013 0.0009

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 0.1585 um PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.5623 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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