Detailed information for compound 1251811

Basic information

Technical information
  • TDR Targets ID: 1251811
  • Name: [(2S)-2-acetyloxypropyl]-trimethylazanium
  • MW: 160.234 | Formula: C8H18NO2+
  • H donors: 0 H acceptors: 1 LogP: 0.6 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](C[N+](C)(C)C)OC(=O)C
  • InChi: 1S/C8H18NO2/c1-7(11-8(2)10)6-9(3,4)5/h7H,6H2,1-5H3/q+1/t7-/m0/s1
  • InChiKey: NZWOPGCLSHLLPA-ZETCQYMHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2S)-2-acetoxypropyl]-trimethyl-ammonium
  • [(2S)-2-acetoxypropyl]-trimethylammonium
  • [(2S)-2-acetyloxypropyl]-trimethyl-azanium
  • CAS-62-51-1
  • NCGC00016282-01
  • Lopac-A-2251
  • NCGC00015045-01
  • ZINC03831050

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus anthracis Anthrax lethal factor Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Rattus norvegicus Muscarinic acetylcholine receptor M1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis serotonin receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Schistosoma mansoni amine GPCR Muscarinic acetylcholine receptor M1   460 aa 463 aa 27.0 %
Loa Loa (eye worm) hypothetical protein Muscarinic acetylcholine receptor M1   460 aa 425 aa 22.1 %
Echinococcus granulosus biogenic amine 5HT receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Muscarinic acetylcholine receptor M1   460 aa 462 aa 23.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0164 0.0151
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.0178
Brugia malayi jmjC domain containing protein 0.0103 0.0496 0.0954
Brugia malayi Pre-SET motif family protein 0.0037 0.0134 0.0247
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0259 0.0247
Echinococcus granulosus serotonin receptor 0.0043 0.0167 0.039
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.0107 0.0094
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1502 0.2849
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0146 0.0133
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0043 0.0167 0.0402
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0562 0.3007 0.5864
Brugia malayi Bromodomain containing protein 0.0031 0.0105 0.019
Schistosoma mansoni hypothetical protein 0.0736 0.3962 1
Onchocerca volvulus 0.0052 0.0219 0.0346
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0044 0.0132
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0044 0.0031
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0105 0.019
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Echinococcus granulosus geminin 0.0736 0.3962 1
Onchocerca volvulus 0.004 0.0149 0.0207
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0948 0.5122 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0174 0.0227
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.0424
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0267
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus granulosus axis inhibition protein axin 0.0023 0.006 0.0119
Echinococcus granulosus hypothetical protein 0.0043 0.0167 0.039
Mycobacterium ulcerans hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0044 0.0031
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus multilocularis RUN 0.002 0.0044 0.0031
Loa Loa (eye worm) hypothetical protein 0.0194 0.0993 0.1926
Echinococcus granulosus neuropeptide receptor 0.0043 0.0167 0.039
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0043 0.0167 0.0402
Brugia malayi PHD-finger family protein 0.0031 0.0105 0.019
Giardia lamblia PHD finger protein 15 0.0031 0.0105 0.019
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0062 0.0106
Onchocerca volvulus 0.0043 0.0167 0.0242
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis allatostatin A receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0164 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.006 0.0119
Loa Loa (eye worm) beta-lactamase 0.004 0.0149 0.0276
Echinococcus multilocularis nardilysin 0.0078 0.0357 0.0345
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0013 0.0009
Brugia malayi cytochrome P450 0.0015 0.0013 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0167 0.0154
Schistosoma mansoni cpg binding protein 0.0034 0.0121 0.0285
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0164 0.0467
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0013 0.0009
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.0174 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0139 0.0157
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0208 0.0494
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0562 0.3007 0.5864
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0167 0.039
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0013 0.0009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0043 0.0167 0.039
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0174 0.05
Loa Loa (eye worm) hypothetical protein 0.0039 0.0146 0.027
Brugia malayi Cytochrome P450 family protein 0.0024 0.0062 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0149 0.0267
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Schistosoma mansoni nardilysin (M16 family) 0.0078 0.0357 0.0884
Brugia malayi hypothetical protein 0.002 0.0044 0.0071
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0303 0.0577
Onchocerca volvulus 0.0043 0.0167 0.0242
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.006 0.0101
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Plasmodium vivax hypothetical protein, conserved 0.004 0.0149 0.0447
Echinococcus multilocularis serotonin receptor 0.0285 0.149 0.148
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.0894 0.1675
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Onchocerca volvulus 0.0287 0.1502 0.2871
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni biogenic amine receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.006 0.0101
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 0.6477
Echinococcus granulosus nardilysin 0.0078 0.0357 0.0873
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0151 0.0351
Schistosoma mansoni cytochrome P450 0.0015 0.0013 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0013 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0174 0.05
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.006 0.0131
Onchocerca volvulus 0.004 0.0149 0.0207
Schistosoma mansoni biogenic amine (5HT) receptor 0.0043 0.0167 0.0402
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0062 0.0106
Schistosoma mansoni transcription factor btf3 0.0038 0.0139 0.0332
Onchocerca volvulus 0.0043 0.0167 0.0242
Mycobacterium ulcerans beta-lactamase 0.004 0.0149 0.0276
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0051 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0177
Brugia malayi RE15519p 0.0043 0.0167 0.0311
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0044 0.0132
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0736 0.3962 1
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0099 0.0275
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.1312 0.255
Loa Loa (eye worm) pax transcription factor protein 2 0.05 0.2669 0.5203
Brugia malayi follicle stimulating hormone receptor 0.0321 0.1687 0.3283
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) ICD-1 protein 0.0038 0.0139 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0099 0.0275
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0948 0.5122 1
Schistosoma mansoni DNA polymerase eta 0.0044 0.0174 0.0421
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0733 0.1417
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Echinococcus granulosus sex peptide receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0167 0.0311
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0149 0.0424
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0149 0.0267
Loa Loa (eye worm) hypothetical protein 0.0037 0.0134 0.0247
Brugia malayi Serotonin receptor 0.0043 0.0167 0.0311
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi ORL1-like opioid receptor 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Trypanosoma brucei unspecified product 0.003 0.0099 0.0275
Trypanosoma brucei C-8 sterol isomerase, putative 0.0379 0.2007 0.6002
Brugia malayi mbt repeat family protein 0.0052 0.0219 0.0414
Echinococcus multilocularis insulin degrading enzyme 0.0078 0.0357 0.0345
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0276
Brugia malayi Pre-SET motif family protein 0.0252 0.1312 0.255
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0167 0.0154
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0013 0.0009
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.006 0.0047
Echinococcus multilocularis nardilysin 0.0078 0.0357 0.0345
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Brugia malayi N-terminal motif family protein 0.0176 0.0894 0.1733
Schistosoma mansoni loxhd1 0.002 0.0044 0.0091
Brugia malayi insulin-degrading enzyme 0.0078 0.0357 0.0684
Toxoplasma gondii toxolysin TLN4 0.0034 0.0121 0.0341
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.0174 0.0421
Loa Loa (eye worm) hypothetical protein 0.0105 0.0505 0.0972
Mycobacterium leprae Probable lipase LipE 0.004 0.0149 1
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.0139 0.0394
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0174 0.0325
Brugia malayi Cytochrome P450 family protein 0.0024 0.0062 0.0106
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.006 0.0119
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0043 0.0167 0.0154
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0044 0.0079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0167 0.0154
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0174 0.05
Onchocerca volvulus Alhambra homolog 0.0031 0.0105 0.012
Trypanosoma brucei unspecified product 0.0044 0.0174 0.05
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0013 0.0009
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0948 0.5122 1
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0149 0.0267
Mycobacterium leprae conserved hypothetical protein 0.004 0.0149 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0321 0.1687 0.3283
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0015
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0013 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.012 0.022
Schistosoma mansoni adenoreceptor 0.0043 0.0167 0.0402
Schistosoma mansoni lipoxygenase 0.0121 0.0597 0.1491
Schistosoma mansoni histamine h1 receptor 0.0043 0.0167 0.0402
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0013 0.0009
Brugia malayi mbt repeat family protein 0.0052 0.0219 0.0414
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0164 0.0382
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0164 0.0394
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0219 0.0524
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0948 0.5122 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0208 0.0505
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0167 0.0154
Leishmania major hypothetical protein, conserved 0.004 0.0149 0.0424
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Chlamydia trachomatis insulinase family protease III 0.0078 0.0357 0.5
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.006 0.0101
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0043 0.0167 0.0154
Onchocerca volvulus Glucosylceramidase homolog 0.0369 0.195 0.3753
Loa Loa (eye worm) hypothetical protein 0.0214 0.1103 0.2141
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.1103 0.2141
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0149 0.0137
Echinococcus granulosus dna polymerase kappa 0.0044 0.0174 0.0409
Brugia malayi Dopamine receptor 0.0043 0.0167 0.0311
Onchocerca volvulus 0.0037 0.0134 0.0177
Schistosoma mansoni opsin-like receptor 0.0043 0.0167 0.0402
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0259 0.0624
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0105 0.0291
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0044 0.0031
Brugia malayi hypothetical protein 0.0016 0.002 0.0023
Brugia malayi MH2 domain containing protein 0.0119 0.0586 0.1131
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0105 0.019
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0013 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.006 0.0101
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0948 0.5122 1
Schistosoma mansoni rab6-interacting 0.002 0.0044 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus granulosus biogenic amine 5HT receptor 0.0285 0.149 0.3742
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0013 0.0014
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0948 0.5122 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.0174 0.0316
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0013 0.0009
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0388 0.2058 0.3948
Loa Loa (eye worm) MBCTL1 0.006 0.0259 0.0491
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0164 0.0467
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0622 0.3338 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.006 0.0259 0.0491
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0044 0.0079
Schistosoma mansoni biogenic amine (5HT) receptor 0.0285 0.149 0.375
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Plasmodium falciparum DNA repair protein REV1, putative 0.0014 0.0008 0.0024
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.006 0.0047
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0948 0.5122 1
Echinococcus granulosus orexin receptor type 2 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.0424
Trypanosoma cruzi peptidase, putative 0.0078 0.0357 0.105
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.0174 0.0325
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0948 0.5122 1
Brugia malayi putative neuropeptide receptor 0.0043 0.0167 0.0311
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0141 0.0128
Brugia malayi isocitrate dehydrogenase 0.0017 0.0028 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0167 0.0154
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0208 0.0505
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.006 0.0119
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0303 0.0291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) RGS-3 protein 0.0023 0.006 0.0101
Schistosoma mansoni hypothetical protein 0.0031 0.0105 0.0245
Echinococcus granulosus neuropeptide receptor A26 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trypanosoma brucei peptidase, putative 0.0078 0.0357 0.105
Echinococcus multilocularis peregrin 0.0031 0.0105 0.0092
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0013 0.0009
Echinococcus multilocularis transient receptor potential ion channel A 0.0101 0.0486 0.0474
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Echinococcus granulosus neuropeptide s receptor 0.0043 0.0167 0.039
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0105 0.0092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0116
Echinococcus multilocularis short transient receptor potential channel 6 0.0069 0.0311 0.0299
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0285 0.149 0.2899
Schistosoma mansoni jumonji domain containing protein 0.0082 0.038 0.0942
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0139 0.0157
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0043 0.0167 0.0311
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0358
Trypanosoma cruzi peptidase, putative 0.0078 0.0357 0.105
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0067 0.0178
Schistosoma mansoni hypothetical protein 0.002 0.0044 0.0091
Echinococcus granulosus tachykinin peptides receptor 99D 0.0043 0.0167 0.039
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 0.6477
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0219 0.0207
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0174 0.0316
Echinococcus granulosus peptide allatostatin:somatostatin 0.0043 0.0167 0.039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0208 0.0195
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0043 0.0167 0.0311
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0622 0.3338 0.6477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Echinococcus granulosus somatostatin receptor 0.0043 0.0167 0.039
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0043 0.0167 0.0311
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0134 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0149 0.0346
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0208 0.0391
Loa Loa (eye worm) hypothetical protein 0.0285 0.149 0.2899
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0149 0.0276
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.1103 0.2141
Schistosoma mansoni family M16 unassigned peptidase (M16 family) 0.0031 0.0101 0.0235
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0177
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0259 0.0247
Toxoplasma gondii NAC domain-containing protein 0.0038 0.0139 0.0394
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0174 0.0325
Echinococcus granulosus neuropeptide FF receptor 2 0.0043 0.0167 0.039
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0012
Leishmania major phosphoglycan beta 1,3 galactosyltransferase 5 0.0078 0.0357 0.105
Onchocerca volvulus 0.05 0.2669 0.5169
Echinococcus granulosus dna polymerase eta 0.0044 0.0174 0.0409
Brugia malayi neuropeptide F receptor 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi PXA domain containing protein 0.0023 0.006 0.0101
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0622 0.3338 1
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Leishmania major hypothetical protein, conserved 0.0025 0.0067 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Loa Loa (eye worm) hypothetical protein 0.0146 0.0733 0.1417
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0043 0.0167 0.0402
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0167 0.0154
Echinococcus granulosus g-protein coupled receptor 0.0043 0.0167 0.039
Brugia malayi Melatonin receptor type 1A 0.0043 0.0167 0.0311
Loa Loa (eye worm) TYRA-2 protein 0.0043 0.0167 0.0311
Echinococcus multilocularis geminin 0.0736 0.3962 0.3954
Schistosoma mansoni transient receptor potential channel 4 0.0105 0.0505 0.1258
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0032 0.0107 0.0194
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0105 0.0314
Echinococcus multilocularis short transient receptor potential channel 6 0.0069 0.0311 0.0299
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Plasmodium falciparum phd finger protein, putative 0.0031 0.0105 0.0314
Echinococcus multilocularis expressed protein 0.0451 0.2399 0.2389
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0259 0.0624
Echinococcus multilocularis dro:myosuppressin receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis G-protein coupled receptor, putative 0.0043 0.0167 0.0154
Schistosoma mansoni regulator of G protein signaling 0.0032 0.0107 0.0251
Brugia malayi Cytochrome P450 family protein 0.0015 0.0013 0.0009
Schistosoma mansoni z-protein (S1r protein) 0.0032 0.0107 0.0251
Schistosoma mansoni biogenic amine receptor 0.0043 0.0167 0.0402
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0948 0.5122 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0303 0.0291
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.1062 0.2657
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0172 0.016
Brugia malayi regulator of G-protein signaling egl-10 0.0032 0.0107 0.0194
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0164 0.0467
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0597 0.148
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0155 0.0361
Loa Loa (eye worm) hypothetical protein 0.0044 0.0174 0.0325
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0028 0.006
Schistosoma mansoni neuropeptide f receptor 76f 0.0043 0.0167 0.0402
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0164 0.0205
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0167 0.0402
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0149 0.0276
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0062 0.0163
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1315 0.2548
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0151 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Echinococcus granulosus dro:myosuppressin receptor 0.0043 0.0167 0.039
Echinococcus granulosus transcription factor btf3 0.0038 0.0139 0.032
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus granulosus 5'partial|nardilysin 0.0034 0.0121 0.0275
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0111 0.0201
Echinococcus granulosus 3'partial|nardilysin 0.0078 0.0357 0.0873
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0167 0.0402
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni myosin xvIII 0.0043 0.0167 0.0402
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0167 0.0402
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0013 0.0009
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0174 0.05
Onchocerca volvulus 0.0032 0.0111 0.0131
Echinococcus granulosus alpha 1A adrenergic receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0176 0.0894 0.1733
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0043 0.0167 0.0154
Echinococcus granulosus biogenic amine 5HT receptor 0.0043 0.0167 0.039
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0028 0.003
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.1062 0.1051
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.006 0.0047
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0586 0.1131
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0013 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Brugia malayi PXA domain containing protein 0.0023 0.006 0.0101
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.006 0.0047
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0167 0.0154
Leishmania major C-8 sterol isomerase-like protein 0.0379 0.2007 0.6002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0043 0.0167 0.0242
Echinococcus granulosus peregrin 0.0031 0.0105 0.0233
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0028 0.0051
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0146 0.027
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.006 0.0119
Trypanosoma brucei transcription factor BTF3, putative 0.0038 0.0139 0.0394
Echinococcus multilocularis G protein coupled receptor 139 0.0043 0.0167 0.0154
Onchocerca volvulus 0.004 0.0149 0.0207
Trichomonas vaginalis esterase, putative 0.004 0.0149 0.0177
Echinococcus granulosus cpg binding protein 0.0034 0.0121 0.0273
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.006 0.0101
Plasmodium falciparum basic transcription factor 3b, putative 0.0038 0.0139 0.0417
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0164 0.0304
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0078 0.0357 0.0884
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0013 0.0009
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0948 0.5122 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0107 0.0194
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0259 0.0491
Echinococcus multilocularis dna polymerase eta 0.0044 0.0174 0.0162
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Brugia malayi hypothetical protein 0.0041 0.0155 0.0288
Onchocerca volvulus 0.0043 0.0167 0.0242
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0276
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0043 0.0167 0.0402
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0105 0.0291
Leishmania major cytochrome p450-like protein 0.0015 0.0013 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0174 0.0325
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0319
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0622 0.3338 0.333
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0219 0.0535
Echinococcus granulosus g protein coupled receptor 0.0043 0.0167 0.039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0167 0.0154
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0303 0.0735
Trypanosoma brucei unspecified product 0.003 0.0099 0.0275
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0043 0.0167 0.0311
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Brugia malayi beta-lactamase 0.004 0.0149 0.0276
Brugia malayi jmjC domain containing protein 0.004 0.0151 0.028
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.006 0.0047
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0379 0.2007 0.3909
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Brugia malayi Dopamine receptor protein 1 0.0043 0.0167 0.0311
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0496 0.1224
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0151 0.0362
Loa Loa (eye worm) insulin-degrading enzyme 0.0078 0.0357 0.0684
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.0174 0.05
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0013 0.0009
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0013 0.0009
Brugia malayi Pax transcription factor protein 2 0.05 0.2669 0.5203
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0174 0.0227
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0134 0.0122
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0167 0.0402
Schistosoma mansoni nardilysin (M16 family) 0.0078 0.0357 0.0884
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0149 0.0276
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0043 0.0167 0.0154
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0319
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0259 0.0635
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.006 0.0101
Echinococcus granulosus axis inhibition protein axin 0.0023 0.006 0.0119
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0041 0.0083
Entamoeba histolytica transcription factor BTF3, putative 0.0038 0.0139 0.0157
Entamoeba histolytica hypothetical protein 0.0038 0.0139 0.0157
Echinococcus granulosus short transient receptor potential channel 6 0.0069 0.0311 0.0757
Schistosoma mansoni transient receptor potential channel 0.0069 0.0311 0.0768
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni cpg binding protein 0.0034 0.0121 0.0285
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0013 0.0009
Onchocerca volvulus 0.0043 0.0167 0.0242
Leishmania major basic transcription factor 3a, putative 0.0038 0.0139 0.0394
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0167 0.0311
Leishmania major DNA polymerase kappa, putative 0.0044 0.0174 0.05
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0067 0.0201
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis orexin receptor type 2 0.0043 0.0167 0.0154
Echinococcus granulosus transient receptor potential gamma protein 0.0105 0.0505 0.1247
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.0174 0.0421
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0043 0.0167 0.0154
Brugia malayi hypothetical protein 0.0023 0.006 0.0101
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0105 0.0245
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.006 0.0131
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0067 0.0201
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.0139 0.0394
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0028 0.006
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus granulosus fmrfamide receptor 0.0043 0.0167 0.039
Brugia malayi AKH receptor 0.0043 0.0167 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0123 0.0279
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0177
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0496 0.0484
Onchocerca volvulus 0.0948 0.5122 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Echinococcus granulosus short transient receptor potential channel 6 0.0069 0.0311 0.0757
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0067 0.0178
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0288 0.0548
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0167 0.0154
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0167 0.0311
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0174 0.0162
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0013 0.0009
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0043 0.0167 0.0311
Schistosoma mansoni opsin-like receptor 0.0043 0.0167 0.0402
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.0174 0.0227
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0622 0.3338 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0164 0.0394
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0028 0.006
Echinococcus granulosus allatostatin A receptor 0.0043 0.0167 0.039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0015
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.006 0.0101
Toxoplasma gondii peptidase M16 inactive domain-containing protein 0.0047 0.019 0.0546
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0151 0.0362
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0164 0.0151
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0174 0.0325
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0172 0.0404
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Echinococcus multilocularis transcription factor btf3 0.0038 0.0139 0.0127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0149 0.0267
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0167 0.0402
Schistosoma mansoni hypothetical protein 0.0041 0.0155 0.0373
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0379 0.2007 0.6002
Brugia malayi G-protein coupled receptor 0.0043 0.0167 0.0311
Schistosoma mansoni alpha-1 adrenergic receptor 0.0043 0.0167 0.0402
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0043 0.0167 0.0311
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0134 0.0379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0177
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0013 0.0009
Schistosoma mansoni insulysin (M16 family) 0.0043 0.0169 0.0407
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0303 0.0735
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0105 0.0233
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni transient receptor potential channel 0.0105 0.0505 0.1258
Onchocerca volvulus 0.0043 0.0167 0.0242
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0208 0.0505
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0028 0.0084
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0013 0.0014
Echinococcus granulosus GPCR family 2 0.0068 0.0303 0.0735
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0597 0.0585
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0099 0.0275
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0267
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0948 0.5122 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0066 0.0292 0.0556
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0277 0.0807
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0013 0.0014
Echinococcus multilocularis neuropeptide FF receptor 2 0.0043 0.0167 0.0154
Brugia malayi putative neuropeptide receptor NPR1 0.0043 0.0167 0.0311
Echinococcus multilocularis neuropeptide s receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0067 0.0201
Loa Loa (eye worm) hypothetical protein 0.0543 0.2902 0.566
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0586 0.1131
Echinococcus multilocularis serotonin receptor 0.0285 0.149 0.148
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Loa Loa (eye worm) hypothetical protein 0.0543 0.2902 0.566
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0167 0.0311
Onchocerca volvulus Neuropeptide F receptor homolog 0.0043 0.0167 0.0242
Leishmania major DNA polymerase eta, putative 0.0044 0.0174 0.05
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0167 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.006 0.0131
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0219 0.0414
Schistosoma mansoni hypothetical protein 0.0318 0.1675 0.4215
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Toxoplasma gondii insulysin, putative 0.0074 0.0337 0.0987
Echinococcus multilocularis nardilysin 0.0047 0.019 0.0177
Loa Loa (eye worm) hypothetical protein 0.0052 0.0219 0.0414
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0208 0.0391
Echinococcus multilocularis g-protein coupled receptor 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Onchocerca volvulus 0.0043 0.0167 0.0242
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0028 0.0039
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0078 0.0357 0.0884
Toxoplasma gondii sporozoite developmental protein 0.0078 0.0357 0.105
Plasmodium vivax basic transcription factor 3b, putative 0.0038 0.0139 0.0417
Brugia malayi hypothetical protein 0.0025 0.0067 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0622 0.3338 1
Toxoplasma gondii rhoptry metalloprotease toxolysin TLN1 0.0078 0.0357 0.105
Schistosoma mansoni lipoxygenase 0.0085 0.0397 0.0985
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0167 0.039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.1103 0.2141
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0303 0.0577
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0167 0.039
Brugia malayi hypothetical protein 0.002 0.0044 0.0071
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0146 0.0733 0.1833
Echinococcus granulosus insulin degrading enzyme 0.0078 0.0357 0.0873
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0028 0.0084
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0167 0.0154
Schistosoma mansoni growth hormone secretagogue receptor 0.0043 0.0167 0.0402
Brugia malayi Cytochrome P450 family protein 0.0034 0.012 0.022
Brugia malayi GnHR receptor homolog 0.0043 0.0167 0.0311
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis neuropeptide receptor A26 0.0043 0.0167 0.0154
Brugia malayi beta-NAC-like protein 0.0038 0.0139 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0167 0.0154
Schistosoma mansoni opsin-like receptor 0.0043 0.0167 0.0402
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0174 0.05
Schistosoma mansoni hypothetical protein 0.0068 0.0303 0.0747
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Giardia lamblia DINP protein human, muc B family 0.0044 0.0174 0.0325
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0013 0.0009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0043 0.0167 0.0311
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0043 0.0167 0.0402
Echinococcus granulosus RUN 0.002 0.0044 0.0079
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0174 0.05
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0622 0.3338 0.8422
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0134 0.0319
Brugia malayi CXXC zinc finger family protein 0.0032 0.0111 0.0201
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0043 0.0167 0.039
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0028 0.0015
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0013 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0177
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0622 0.3338 1
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.006 0.0047
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.0107 0.0239
Echinococcus granulosus transient receptor potential ion channel A 0.0101 0.0486 0.1199
Echinococcus granulosus 7tm_1 domain containing protein 0.0043 0.0167 0.039
Schistosoma mansoni transient receptor potential channel 0.0069 0.0311 0.0768
Loa Loa (eye worm) hypothetical protein 0.0042 0.0164 0.0304
Echinococcus granulosus g protein coupled receptor 0.0043 0.0167 0.039
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.0174 0.0409
Loa Loa (eye worm) doublecortin family protein 0.002 0.0044 0.0071
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0043 0.0167 0.0154
Loa Loa (eye worm) cytochrome P450 0.0015 0.0013 0.0009
Schistosoma mansoni rab6-interacting 0.002 0.0044 0.0091
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0149 0.0267
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.006 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0164 0.0205
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0149 0.0276
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0317 0.0781
Plasmodium vivax SET domain protein, putative 0.0037 0.0134 0.0402
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0402
Brugia malayi neuropeptide F receptor 0.0043 0.0167 0.0311
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0167 0.039
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0062 0.0106
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.0107 0.0239
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0174 0.05
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0622 0.3338 0.8424
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0155 0.0373
Schistosoma mansoni regulator of G protein signaling 0.0023 0.006 0.0131
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0267
Echinococcus multilocularis sex peptide receptor 0.0043 0.0167 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0028 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0043 0.0167 0.039
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0167 0.039
Leishmania major cytochrome p450-like protein 0.0015 0.0013 0.0014
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0219 0.0535
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Onchocerca volvulus 0.0043 0.0167 0.0242
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0028 0.0015
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0164 0.0467
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0167 0.0154
Brugia malayi sulfakinin receptor protein 0.0043 0.0167 0.0311
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0208 0.0494
Trichomonas vaginalis glucosylceramidase, putative 0.0369 0.195 0.3734
Schistosoma mansoni biogenic amine receptor 0.0043 0.0167 0.0402
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.006 0.0131
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0948 0.5122 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0071
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0043 0.0167 0.0311
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0043 0.0167 0.0402
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0164 0.0304
Trichomonas vaginalis glucosylceramidase, putative 0.0388 0.2058 0.3948
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0134 0.0307
Schistosoma mansoni polycystin 1-related 0.002 0.0044 0.0091
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0167 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0139 0.0157
Loa Loa (eye worm) melatonin receptor type 1A 0.0043 0.0167 0.0311
Schistosoma mansoni axis inhibition protein axin 0.0023 0.006 0.0131
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0358
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0219 0.0535
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0167 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.006 0.0047
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0146 0.0337
Brugia malayi G protein-coupled receptor 0.0043 0.0167 0.0311
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0219 0.0346
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0149 0.0267
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0303 0.0577
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0232
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0208 0.0195
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.006
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.006 0.0131
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.0008 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.0178
Echinococcus multilocularis cpg binding protein 0.0034 0.0121 0.0108
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0276
Loa Loa (eye worm) hypothetical protein 0.0379 0.2007 0.3909
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0164 0.0382
Entamoeba histolytica hypothetical protein 0.0041 0.0155 0.0189
Schistosoma mansoni neuropeptide receptor 0.0043 0.0167 0.0402
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0622 0.3338 1
Brugia malayi Dopamine receptor protein 2 0.0043 0.0167 0.0311
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0167 0.0402
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0149 0.0267
Brugia malayi Tachykinin-like peptides receptor 99D 0.0043 0.0167 0.0311
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0043 0.0167 0.0311
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0164 0.0205
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0062 0.0163
Echinococcus multilocularis transient receptor potential gamma protein 0.0105 0.0505 0.0493
Brugia malayi G-protein coupled receptor 0.0043 0.0167 0.0311
Echinococcus granulosus g protein coupled receptor 0.0043 0.0167 0.039
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0028 0.0039
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0164 0.0382
Echinococcus multilocularis GPCR, family 2 0.0068 0.0303 0.0291
Echinococcus granulosus G protein coupled receptor 139 0.0043 0.0167 0.039
Trichomonas vaginalis glucosylceramidase, putative 0.0562 0.3007 0.5822
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0311
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0062 0.0163
Loa Loa (eye worm) hypothetical protein 0.0054 0.0228 0.043
Brugia malayi hypothetical protein 0.0043 0.0167 0.0311
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0062 0.0106
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0043 0.0167 0.039
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0167 0.039
Brugia malayi larval opioid receptor 0.0043 0.0167 0.0311
Brugia malayi Serotonin receptor 0.0043 0.0167 0.0311
Brugia malayi hypothetical protein 0.0023 0.006 0.0101
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0219 0.0207
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0219 0.0524
Loa Loa (eye worm) hypothetical protein 0.0068 0.0303 0.0577
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0044 0.0079
Toxoplasma gondii hypothetical protein 0.0031 0.0101 0.0278
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0164 0.0205
Leishmania major cytochrome p450-like protein 0.0024 0.0062 0.0163
Schistosoma mansoni cpg binding protein 0.0032 0.0111 0.026
Toxoplasma gondii ABC1 family protein 0.004 0.0149 0.0424
Schistosoma mansoni amine GPCR 0.0043 0.0167 0.0402
Brugia malayi Doublecortin family protein 0.002 0.0044 0.0071
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0622 0.3338 0.6513
Echinococcus multilocularis somatostatin receptor 0.0043 0.0167 0.0154
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.006 0.0119
Schistosoma mansoni axis inhibition protein axin 0.0023 0.006 0.0131
Echinococcus granulosus neuropeptide receptor 0.0043 0.0167 0.039
Echinococcus granulosus expressed protein 0.0451 0.2399 0.6043
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.0107 0.0094
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.006 0.0047
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0948 0.5122 1
Mycobacterium ulcerans lipase LipD 0.004 0.0149 0.0276
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0043 0.0167 0.0154
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0155 0.0143
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0319

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 0.1585 um PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.5623 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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