Detailed information for compound 1307107

Basic information

Technical information
  • TDR Targets ID: 1307107
  • Name: N-(3-cyanophenyl)-3-cyclopentylpropanamide
  • MW: 242.316 | Formula: C15H18N2O
  • H donors: 1 H acceptors: 2 LogP: 3.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1cccc(c1)NC(=O)CCC1CCCC1
  • InChi: 1S/C15H18N2O/c16-11-13-6-3-7-14(10-13)17-15(18)9-8-12-4-1-2-5-12/h3,6-7,10,12H,1-2,4-5,8-9H2,(H,17,18)
  • InChiKey: SSUSYALOZVUREO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-cyanophenyl)-3-cyclopentyl-propanamide
  • N-(3-cyanophenyl)-3-cyclopentyl-propionamide
  • ZINC00618437
  • MLS000063595
  • SMR000075196

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major cathepsin L-like protease 0.0074 0.0665 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0036 0.0231 0.0231
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.0018 0.0018
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0902 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0231 0.0213
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0048 0.0032
Schistosoma mansoni jumonji domain containing protein 0.0089 0.0828 0.0811
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1773 1
Brugia malayi Cathepsin L-like precursor 0.0019 0.0048 0.0048
Echinococcus multilocularis GPCR, family 2 0.0035 0.0218 0.0201
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.3809 0.378
Echinococcus granulosus importin subunit beta 1 0.003 0.0161 0.0144
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0058 0.0484 0.0414
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0058 0.0484 0.045
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0302 0.3239 0.3227
Onchocerca volvulus Alhambra homolog 0.0034 0.0212 0.0661
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0088 0.0375
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Loa Loa (eye worm) hypothetical protein 0.0035 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0043 0.0317 0.0317
Brugia malayi CHD4 protein 0.0017 0.0025 0.0025
Brugia malayi Cathepsin L-like precursor 0.0019 0.0048 0.0048
Leishmania major cathepsin L-like protease 0.0019 0.0048 0.0011
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0048 0.0048
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0662 0.0645
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0302 0.0285
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0659 0.0642
Giardia lamblia Phosphatidylinositol 4-kinase 0.0058 0.0484 0.0414
Loa Loa (eye worm) hypothetical protein 0.0075 0.0671 0.0671
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0036 0.0231 0.0213
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0058 0.0484 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.0439
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0036 0.0231 0.0213
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0073 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7919 0.7915
Schistosoma mansoni hypothetical protein 0.0103 0.0989 0.0973
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0231 0.0231
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0112 0.1096 0.1063
Brugia malayi hypothetical protein 0.0142 0.1435 0.1435
Echinococcus granulosus FTZ F1 alpha 0.0036 0.0231 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0343 0.0327
Loa Loa (eye worm) hypothetical protein 0.0092 0.0862 0.0862
Brugia malayi PHD-finger family protein 0.0032 0.0188 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0058 0.0484 0.0467
Leishmania major cathepsin L-like protease 0.0074 0.0665 0.063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Schistosoma mansoni importin beta-1 0.003 0.0161 0.0144
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0104 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0036 0.0231 0.0231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0022
Echinococcus granulosus lamin 0.0093 0.0882 0.0865
Loa Loa (eye worm) hypothetical protein 0.0019 0.0041 0.0041
Onchocerca volvulus 0.0032 0.0185 0.0567
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0043
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0058 0.0484 0.0439
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0088 0.0375
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.045
Schistosoma mansoni cpg binding protein 0.0032 0.0185 0.0167
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0043
Brugia malayi cytoplasmic intermediate filament protein 0.005 0.0392 0.0392
Onchocerca volvulus 0.0277 0.2957 1
Entamoeba histolytica hypothetical protein 0.0042 0.0302 0.0256
Onchocerca volvulus 0.0023 0.0088 0.0239
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.0073
Onchocerca volvulus 0.0058 0.0484 0.1587
Brugia malayi jmjC domain containing protein 0.0045 0.0339 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0171 0.1752 0.1739
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0232 0.0232
Brugia malayi Heterochromatin protein 1 0.0081 0.0746 0.0746
Leishmania major cathepsin L-like protease 0.0019 0.0048 0.0011
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0088 0.0375
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7919 0.7915
Leishmania major phosphatidylinositol 4-kinase, putative 0.0058 0.0484 0.045
Schistosoma mansoni lamin 0.0093 0.0882 0.0865
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0036 0.0231 0.0231
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0058 0.0484 0.045
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0058 0.0484 0.0467
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0058 0.0484 0.045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0017 0.0018 0.0018
Onchocerca volvulus Huntingtin homolog 0.0142 0.1435 0.482
Leishmania major phosphatidylinositol 3-kinase, putative 0.0302 0.3239 0.3215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0171 0.1752 0.1739
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0058 0.0484 0.0467
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0088 0.0052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0171 0.1752 0.1752
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0302 0.3239 0.3227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0539 0.5906 0.59
Entamoeba histolytica hypothetical protein 0.0058 0.0484 0.0439
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0746 0.0746
Trichomonas vaginalis PIKK family atypical protein kinase 0.0302 0.3239 0.3229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0058 0.0484 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0989 0.0989
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0171 0.1752 0.1737
Loa Loa (eye worm) hypothetical protein 0.0142 0.1435 0.1435
Brugia malayi hypothetical protein 0.0016 0.0007 0.0007
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.3386 0.3386
Schistosoma mansoni zinc finger protein 0.0025 0.0115 0.0097
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.1061 0.1061
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0058 0.0484 0.0467
Onchocerca volvulus 0.0019 0.0048 0.0101
Echinococcus multilocularis survival motor neuron protein 1 0.0505 0.5522 0.5514
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0073 0.0037
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0058 0.0484 0.0469
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0041 0.0292 0.0257
Brugia malayi chromobox protein homolog 3 0.0046 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0056 0.0462 0.0444
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0902 1 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0088 0.0041
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0022 0.5
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.0484 0.0469
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0088 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus granulosus ecdysone induced protein 78C 0.0036 0.0231 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0486 0.5312 0.5305
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.0018 0.0018
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0058 0.0484 0.0467
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0375 0.4053 0.4031
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.0439
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0218 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Echinococcus multilocularis lamin 0.0093 0.0882 0.0865
Schistosoma mansoni hypothetical protein 0.0035 0.0218 0.0201
Loa Loa (eye worm) DR-78 0.0017 0.0018 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0231 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0487 0.5321 0.5313
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0073 0.0056
Schistosoma mansoni hypothetical protein 0.0034 0.0212 0.0195
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0171 0.1752 0.1712
Trichomonas vaginalis PIKK family atypical protein kinase 0.0487 0.5321 0.5313
Loa Loa (eye worm) hypothetical protein 0.0132 0.1315 0.1315
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0231 0.0213
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.3809 0.5
Brugia malayi hypothetical protein 0.0017 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7919 0.7915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0098 0.0083
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0098 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0036 0.0231 0.0231
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0171 0.1752 0.1737
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0171 0.1752 0.1722
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0043
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0302 0.0285
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0231 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0058 0.0484 0.0467
Trichomonas vaginalis PIKK family atypical protein kinase 0.0487 0.5321 0.5313
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0088 0.0052
Plasmodium falciparum phd finger protein, putative 0.0034 0.0212 0.4111
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0041 0.0292 0.0275
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0058 0.0484 0.0469
Brugia malayi tailless protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) cysteine protease 0.0019 0.0048 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.0056 0.0462 0.0444
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0218 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.077 0.8513 0.851
Echinococcus multilocularis cysteine protease 0.0019 0.0048 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1315 0.1302
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0109 0.0109
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0058 0.0484 0.0469
Echinococcus granulosus chromobox protein 1 0.0081 0.0746 0.073
Loa Loa (eye worm) hypothetical protein 0.0142 0.1435 0.1435
Loa Loa (eye worm) hypothetical protein 0.0019 0.0041 0.0041
Brugia malayi RNA binding protein 0.0074 0.0659 0.0659
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0058 0.0484 0.0414
Leishmania major cathepsin L-like protease 0.0019 0.0048 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0104 0.1778
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0671 0.0671
Trichomonas vaginalis PIKK family atypical protein kinase 0.0302 0.3239 0.3229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0302 0.3239 0.3229
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0302 0.3239 0.3215
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Echinococcus multilocularis peregrin 0.0037 0.0245 0.0227
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0058 0.0484 0.0467
Echinococcus granulosus microtubule associated protein 2 0.0806 0.8922 0.892
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0665 0.063
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0048 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0056 0.0462 0.0444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0042 0.0302 0.0256
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.0484 0.0484
Onchocerca volvulus 0.0093 0.0882 0.2938
Echinococcus multilocularis serine protein kinase ATM 0.0171 0.1752 0.1737
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.0484 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.1096 0.1082
Brugia malayi nuclear receptor RXR 0.0019 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0171 0.1752 0.1712
Schistosoma mansoni coup transcription factor 0.0036 0.0231 0.0213
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0041 0.0041
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0902 1 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0073 0.1105
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0484 0.045
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0104 0.0068
Schistosoma mansoni microtubule-associated protein tau 0.0806 0.8922 0.892
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0088
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0104 0.1778
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0665 0.063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0036 0.0231 0.0231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus granulosus lamin dm0 0.0093 0.0882 0.0865
Echinococcus granulosus cpg binding protein 0.0036 0.0231 0.0214
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0056 0.0462 0.0444
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0484 0.045
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0902 1 1
Echinococcus granulosus GPCR family 2 0.0035 0.0218 0.0201
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0093 0.0882 0.0882
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0147 0.1487 0.1472
Echinococcus multilocularis zinc finger protein 0.0025 0.0115 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0302 0.3239 0.3229
Onchocerca volvulus 0.0019 0.0048 0.0101
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0058 0.0484 1
Brugia malayi nuclear receptor RXR 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0103 0.0989 0.3305
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0036 0.0231 0.0213
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0382 0.0367
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0068 0.0592 0.0558
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Schistosoma mansoni lamin 0.0093 0.0882 0.0865
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0058 0.0484 0.045
Loa Loa (eye worm) phosphatidylinositol kinase 0.0058 0.0484 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0036 0.0231 0.0231
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0484 0.0595
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.0484 0.2684
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.0439
Loa Loa (eye worm) hepatopoietin HPO2 0.0041 0.0292 0.0292
Leishmania major phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.045
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0041 0.0023
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0902 1 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.0484 0.0467
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0059 0.0043
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.0484 0.0467
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0112 0.1086 0.107
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0098 0.0083
Loa Loa (eye worm) hypothetical protein 0.0043 0.0317 0.0317
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0132 0.1315 0.13
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0218 0.0201
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.3809 0.378
Trichomonas vaginalis ran, putative 0.0022 0.0073 0.0058
Echinococcus multilocularis musashi 0.0093 0.0882 0.0865
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.0484 0.0469
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.021 0.2195 0.7408
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0025 0.0007
Entamoeba histolytica hypothetical protein 0.0024 0.0098 0.0051
Echinococcus multilocularis chromobox protein 1 0.0081 0.0746 0.073
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) phosphatidylinositol 3 0.0302 0.3239 0.3239
Schistosoma mansoni chromobox protein 0.0081 0.0746 0.073
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0088 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Loa Loa (eye worm) hypothetical protein 0.0085 0.0791 0.0791
Echinococcus multilocularis FTZ F1 alpha 0.0036 0.0231 0.0213
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0058 0.0484 0.045
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0161 0.0155
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0073 0.0035
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0132 0.1315 0.13
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0484 0.0595
Echinococcus granulosus cathepsin l1 0.0019 0.0048 0.003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0036 0.0231 0.0213
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0048 0.003
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0036 0.0231 0.0213
Brugia malayi ecdysteroid receptor 0.0036 0.0231 0.0231
Schistosoma mansoni thyroid hormone receptor 0.0183 0.189 0.1875
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0339 0.0322
Brugia malayi nuclear receptor NHR-88 0.0017 0.0018 0.0018
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0058 0.0484 0.0467
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0302 0.3239 0.3227
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0041 0.0023
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0484 1
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0048 0.0048
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0185 0.0185
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0048 0.0548
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0036 0.0231 0.0231
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0073 0.0037
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0018 0.0018
Entamoeba histolytica Ran family GTPase 0.0022 0.0073 0.0026
Brugia malayi hypothetical protein 0.0042 0.0302 0.0302
Leishmania major phosphatidylinositol kinase, putative 0.0058 0.0484 0.045
Loa Loa (eye worm) hypothetical protein 0.0019 0.0041 0.0041
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0293 0.0276
Brugia malayi nuclear hormone receptor 0.0017 0.0018 0.0018
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0155 0.0138
Brugia malayi Cathepsin L-like precursor 0.0019 0.0048 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0041 0.0292 0.0257
Loa Loa (eye worm) hypothetical protein 0.0112 0.1096 0.1096
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0746 0.0732
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0902 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0147 0.1487 0.1472
Trichomonas vaginalis PIKK family atypical protein kinase 0.0486 0.5312 0.5305
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0318 0.03
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0447 0.043
Echinococcus multilocularis muscleblind protein 1 0.0164 0.1683 0.1668
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.006 0.0042
Onchocerca volvulus 0.0036 0.0231 0.0723
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Schistosoma mansoni steroid hormone receptor ad4bp 0.0036 0.0231 0.0213
Brugia malayi Bromodomain containing protein 0.0037 0.0245 0.0245
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0041 0.0023
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0484 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0057 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0242 0.2557 0.2546
Leishmania major phosphatidylinositol kinase related protein, putative 0.0058 0.0484 0.045
Giardia lamblia PHD finger protein 15 0.0034 0.0212 0.014
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.3809 0.3763
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0058 0.0484 0.045
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0363 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Toxoplasma gondii Erv1 / Alr family protein 0.0041 0.0292 0.0333
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0587 0.6448 0.6442
Brugia malayi Pre-SET motif family protein 0.0244 0.2578 0.2578
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0048 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0045 0.0337 0.0319
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0212 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Brugia malayi RNA, U transporter 1 0.0084 0.0776 0.0776
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0048 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0231 0.0231
Brugia malayi hypothetical protein 0.0019 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0088
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0058 0.0484 0.045
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0036 0.0231 0.0213
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0048 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0599 0.0582
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0302 0.3239 0.3239
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0058 0.0484 0.0469
Loa Loa (eye worm) hypothetical protein 0.0505 0.5522 0.5522
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0048
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0025 0.0007
Leishmania major hypothetical protein, conserved 0.0025 0.0104 0.0068
Schistosoma mansoni ran 0.0022 0.0073 0.0056
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0447 0.0447
Entamoeba histolytica hypothetical protein 0.0058 0.0484 0.0439
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0098 0.0062
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0484 0.0595
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1773 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0022
Trichomonas vaginalis set domain proteins, putative 0.0277 0.2957 0.2946
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0339 0.0322
Brugia malayi hypothetical protein 0.0017 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1096 0.1082
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0659 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0539 0.5906 0.59
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1972 0.1959
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0218 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0048 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0585 0.6431 0.6426
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1773 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0171 0.1752 0.1752
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0551 0.0685
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0659 0.0642
Onchocerca volvulus Bile acid receptor homolog 0.0036 0.0231 0.0723
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.0484 0.0469
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0048 0.0101
Brugia malayi Steroid receptor seven-up type 2 0.0036 0.0231 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0447 0.043
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.006 0.0042
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0302 0.3239 0.3215
Loa Loa (eye worm) hypothetical protein 0.0045 0.0337 0.0337
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0036 0.0231 0.0213
Schistosoma mansoni bromodomain containing protein 0.0078 0.071 0.0694
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0218 0.0218
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0229 0.0247
Loa Loa (eye worm) hypothetical protein 0.0046 0.0343 0.0343
Brugia malayi Importin beta-1 subunit 0.003 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0053 0.0429 0.0429
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0104 0.0068
Plasmodium vivax hypothetical protein 0.0058 0.0484 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0207 0.0189
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0447 0.043
Onchocerca volvulus 0.0019 0.0048 0.0101
Loa Loa (eye worm) hypothetical protein 0.0093 0.0882 0.0882
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.0018 0.0018
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0048 0.003
Echinococcus granulosus chromobox protein 1 0.0081 0.0746 0.073
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0036 0.0231 0.0213
Onchocerca volvulus 0.0049 0.038 0.123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0902 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0048 0.003
Brugia malayi hypothetical protein 0.0019 0.0041 0.0041
Echinococcus granulosus serine protein kinase ATM 0.0171 0.1752 0.1737
Echinococcus multilocularis cysteine protease 0.0019 0.0048 0.003
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.0439
Echinococcus multilocularis thyroid hormone receptor alpha 0.0183 0.189 0.1875
Loa Loa (eye worm) steroid hormone receptor 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0025 0.0104 0.0104
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.0484 0.0484
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0746 0.0732
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0212 0.0195
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.0484 0.0484
Plasmodium vivax SET domain protein, putative 0.0036 0.0229 0.4478
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0212 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Loa Loa (eye worm) nuclear receptor NHR-67 0.0017 0.0018 0.0018
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0058 0.0484 0.0467
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.006 0.0042
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0058 0.0484 0.0467
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0231 0.0231
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0484 0.045
Mycobacterium ulcerans hypothetical protein 0.0023 0.0088 0.0375
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0665 0.063
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0058 0.0484 0.0469
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0088 0.0433
Schistosoma mansoni hypothetical protein 0.0018 0.0036 0.0019
Echinococcus granulosus zinc finger protein 0.0025 0.0115 0.0097
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.1061 0.1061
Loa Loa (eye worm) nuclear hormone receptor 0.0017 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0229 0.0212
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0073 0.0037
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0041 0.0292 0.0257
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Brugia malayi Cathepsin L-like precursor 0.0019 0.0048 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus granulosus tar DNA binding protein 0.0074 0.0659 0.0642
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.005 0.0392 0.0392
Echinococcus multilocularis chromobox protein 1 0.0081 0.0746 0.073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0539 0.5906 0.59
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.0484 0.0484
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0019 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0534 0.5846 0.5839
Trichomonas vaginalis PIKK family atypical protein kinase 0.0486 0.5312 0.5305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0302 0.3239 0.3229
Mycobacterium leprae conserved hypothetical protein 0.0058 0.0484 0.2352
Leishmania major importin beta-1 subunit, putative 0.0024 0.0098 0.0062
Loa Loa (eye worm) hypothetical protein 0.0184 0.1901 0.1901
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0088 0.0433
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.7393 0.7389
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0022 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0339 0.0339
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0229 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0036 0.0231 0.0231
Brugia malayi Muscleblind-like protein 0.0164 0.1683 0.1683
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0426 0.4639 0.4619
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0192 0.0177
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0058 0.0484 0.0467
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0036 0.0231 0.0723
Loa Loa (eye worm) phosphatidylinositol 3 0.0902 1 1
Onchocerca volvulus 0.0093 0.0882 0.2938
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0161 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0171 0.1752 0.1739
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0058 0.0484 0.0469
Onchocerca volvulus Huntingtin homolog 0.0142 0.1435 0.482
Schistosoma mansoni hypothetical protein 0.0035 0.0218 0.0201
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0041 0.0292 0.5844
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0718 0.7927 0.792
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0048 0.0548
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0036 0.0231 0.0231
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0041 0.0041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0447 0.043
Brugia malayi nuclear hormone receptor 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0231 0.0231
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.0073
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0041 0.0292 0.0257
Toxoplasma gondii Erv1 / Alr family protein 0.0041 0.0292 0.0333
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0058 0.0484 0.0467
Trichomonas vaginalis PIKK family atypical protein kinase 0.0902 1 1
Plasmodium vivax vivapain-2 0.0019 0.0048 0.0548
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0171 0.1752 0.1722
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0036 0.0231 0.0231
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.0058 0.0484 0.045
Leishmania major GTP-binding protein, putative 0.0022 0.0073 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.0484 0.0484
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.0439
Brugia malayi jmjC domain containing protein 0.0112 0.1086 0.1086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Plasmodium falciparum importin beta, putative 0.003 0.0161 0.301
Schistosoma mansoni ran 0.0022 0.0073 0.0056
Echinococcus multilocularis cpg binding protein 0.0036 0.0231 0.0214
Brugia malayi FAT domain containing protein 0.0132 0.1315 0.1315
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0318 0.03
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0659 0.0642
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0041 0.0292 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0192 0.0177
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0058 0.0484 0.0469
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0088 0.0375
Entamoeba histolytica hypothetical protein 0.0058 0.0484 0.0439
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0058 0.0484 0.0469
Brugia malayi nuclear receptor NHR-67 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Loa Loa (eye worm) hypothetical protein 0.0109 0.1061 0.1061
Brugia malayi steroid hormone receptor 0.0036 0.0231 0.0231
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0088 0.0375
Brugia malayi CXXC zinc finger family protein 0.0032 0.0185 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0902 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0447 0.043
Echinococcus multilocularis ecdysone induced protein 78C 0.0036 0.0231 0.0213
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0048 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0048 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0605 0.6651 0.6646
Onchocerca volvulus Protein ultraspiracle homolog 0.0036 0.0231 0.0723
Giardia lamblia GTOR 0.0902 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.0484 0.0484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0058 0.0484 0.0439
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0048 0.0011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0212 0.0212
Entamoeba histolytica protein kinase rad3, putative 0.0171 0.1752 0.1712
Brugia malayi Cathepsin L-like precursor 0.0019 0.0048 0.0048
Brugia malayi conserved hypotetical protein 0.0017 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.038 0.0362
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.0484 0.0484
Onchocerca volvulus 0.0019 0.0048 0.0101
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0058 0.0484 1
Giardia lamblia Hypothetical protein 0.0058 0.0484 0.0414
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0036 0.0231 0.0213
Brugia malayi PHD-finger family protein 0.0034 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0058 0.0484 0.0484
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0659 0.0642
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0155 0.0138
Loa Loa (eye worm) hypothetical protein 0.0171 0.1752 0.1752
Brugia malayi hypothetical protein 0.0025 0.0104 0.0104
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0088 0.0041
Brugia malayi Bromodomain containing protein 0.0092 0.087 0.087
Trypanosoma cruzi target of rapamycin kinase 3 0.0718 0.7927 0.792
Echinococcus granulosus intermediate filament protein 0.0093 0.0882 0.0865
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0104 0.0068
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0484 0.0595
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0058 0.0484 0.0467
Onchocerca volvulus 0.0019 0.0048 0.0101
Schistosoma mansoni chromobox protein 0.0081 0.0746 0.073
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0048 0.0011
Echinococcus granulosus peregrin 0.0037 0.0245 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7919 0.7915
Schistosoma mansoni hypothetical protein 0.0035 0.0218 0.0201
Schistosoma mansoni cpg binding protein 0.0036 0.0231 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0902 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0231 0.0213
Entamoeba histolytica hypothetical protein 0.0058 0.0484 0.0439
Brugia malayi photoreceptor-specific nuclear receptor 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0058 0.0484 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0343 0.0327
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0218 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0058 0.0484 0.0484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0447 0.0447
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0025 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0042 0.0302 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0231 0.0231
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.0484 0.0469
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0058 0.0484 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0043
Echinococcus granulosus snurportin 1 0.0315 0.3386 0.3374
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0212 0.4111
Loa Loa (eye worm) hypothetical protein 0.021 0.2195 0.2195
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.0484 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0231 0.0231
Schistosoma mansoni cpg binding protein 0.0036 0.0231 0.0214
Loa Loa (eye worm) hypothetical protein 0.0164 0.1683 0.1683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Brugia malayi hypothetical protein 0.0505 0.5522 0.5522
Loa Loa (eye worm) ctsf protein 0.0019 0.0048 0.0048
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0486 0.0451
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0104 0.1778
Echinococcus multilocularis importin subunit beta 1 0.003 0.0161 0.0144
Toxoplasma gondii target of rapamycin (TOR), putative 0.0671 0.7393 1
Leishmania major cathepsin L-like protease 0.0019 0.0048 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0534 0.5846 0.5839
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.1105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0041 0.0023
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0041 0.0292 0.5844
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0036 0.0231 0.0213
Brugia malayi Bromodomain containing protein 0.0046 0.035 0.035
Echinococcus multilocularis Zinc finger, PHD finger 0.0058 0.0484 0.0467
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0902 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0088 0.0375
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Echinococcus granulosus muscleblind protein 0.0164 0.1683 0.1668
Brugia malayi N-terminal motif family protein 0.021 0.2195 0.2195
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0036 0.0231 0.0213
Onchocerca volvulus 0.0019 0.0048 0.0101
Brugia malayi SET domain containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0164 0.1683 0.1683
Brugia malayi Cathepsin L-like precursor 0.0019 0.0048 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0036 0.0231 0.0231
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0058 0.0484 0.0469
Echinococcus granulosus survival motor neuron protein 1 0.0505 0.5522 0.5514
Entamoeba histolytica hypothetical protein 0.0042 0.0302 0.0256
Loa Loa (eye worm) hypothetical protein 0.003 0.0161 0.0161
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0447 0.043
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0058 0.0484 0.0467
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0902 1 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0036 0.0231 0.0213
Echinococcus multilocularis lamin dm0 0.0093 0.0882 0.0865
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0058 0.0484 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0302 0.0285
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0231 0.0213
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Echinococcus multilocularis 0.0058 0.0484 0.0467
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0025 0.0109 0.0091
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0036 0.0231 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0058 0.0484 0.045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0043
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0036 0.0231 0.0213
Loa Loa (eye worm) RNA binding protein 0.0074 0.0659 0.0659
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0059 0.0043
Loa Loa (eye worm) hypothetical protein 0.0056 0.0462 0.0462
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0043
Schistosoma mansoni hypothetical protein 0.0075 0.0671 0.0654
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.0484 0.0484
Entamoeba histolytica hypothetical protein 0.0042 0.0302 0.0256
Leishmania major cathepsin L-like protease 0.0074 0.0665 0.063
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0363 0.0345
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0718 0.7927 0.792
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0112 0.1086 0.107
Toxoplasma gondii non-specific serine/threonine protein kinase 0.019 0.1972 0.2619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7919 0.7915
Echinococcus granulosus geminin 0.0587 0.6448 0.6442
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0022 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0048 0.0032
Schistosoma mansoni hypothetical protein 0.0315 0.3386 0.3374
Schistosoma mansoni fkbp-rapamycin associated protein 0.0171 0.1752 0.1737
Plasmodium vivax vivapain-2 0.0019 0.0048 0.0548
Leishmania major hypothetical protein, unknown function 0.0058 0.0484 0.045
Schistosoma mansoni intermediate filament proteins 0.0093 0.0882 0.0865
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0048 0.0548
Schistosoma mansoni hypothetical protein 0.0035 0.0218 0.0201
Brugia malayi ecdysone receptor 0.0017 0.0018 0.0018
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.1061 0.1061
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0036 0.0231 0.0231
Echinococcus multilocularis microtubule associated protein 2 0.0806 0.8922 0.892
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.006 0.0042
Schistosoma mansoni hypothetical protein 0.0132 0.1315 0.13
Loa Loa (eye worm) fibroinase 0.0019 0.0048 0.0048
Brugia malayi TAR-binding protein 0.0074 0.0659 0.0659
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0447 0.043
Leishmania major hypothetical protein, conserved 0.0041 0.0292 0.0257
Schistosoma mansoni hypothetical protein 0.0147 0.1487 0.1472
Brugia malayi nuclear receptor NHR-88 0.0036 0.0231 0.0231
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0212 0.0212
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0382 0.1238
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0484 0.0595
Echinococcus multilocularis snurportin 1 0.0315 0.3386 0.3374
Schistosoma mansoni zinc finger protein 0.0018 0.0036 0.0019
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0058 0.0484 0.0467
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0058 0.0484 0.0467
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0058 0.0484 0.045
Leishmania major cathepsin L-like protease 0.0019 0.0048 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0339 0.0322
Toxoplasma gondii FATC domain-containing protein 0.0171 0.1752 0.232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Loa Loa (eye worm) hypothetical protein 0.019 0.1972 0.1972
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0218 0.0218
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.0484 0.0467
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0088 0.0088
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0231 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0484 0.0469
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0662 0.0645
Loa Loa (eye worm) hypothetical protein 0.0046 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0058 0.0487 0.0487
Loa Loa (eye worm) intermediate filament protein 0.0093 0.0882 0.0882
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.0484 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0487 0.5321 0.5313
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0302 0.3239 0.3215
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0902 1 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0383 0.0383
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0088 0.0088
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0088 0.0375
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0302 0.3239 0.3215
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0621 0.0621
Brugia malayi Augmenter of liver regeneration 0.0041 0.0292 0.0292
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0161 0.0125
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0045 0.0337 0.0319
Onchocerca volvulus 0.0058 0.0484 0.1587
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0212 0.0224
Brugia malayi Pre-SET motif family protein 0.0036 0.0229 0.0229
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3809 0.3799
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0484 0.0469
Schistosoma mansoni retinoic acid receptor RXR 0.0036 0.0231 0.0213
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0058 0.0484 0.0484
Onchocerca volvulus 0.0019 0.0048 0.0101
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0058 0.0484 0.0467
Schistosoma mansoni survival motor neuron protein 0.0103 0.0989 0.0973
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0048 0.003
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0171 0.1752 0.1722
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0665 0.063
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0058 0.0484 1
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0382 0.0367
Echinococcus multilocularis geminin 0.0587 0.6448 0.6442
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0343 0.1105
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0244 0.2578 0.2578
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0659 0.0642
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0171 0.1752 0.1737
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0212 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0022 0.0006
Echinococcus multilocularis muscleblind protein 0.0164 0.1683 0.1668
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0665 0.063
Brugia malayi intermediate filament protein 0.0093 0.0882 0.0882
Schistosoma mansoni hypothetical protein 0.0587 0.6448 0.6442
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0155 0.0138
Plasmodium vivax importin-beta 2, putative 0.003 0.0161 0.301
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0058 0.0484 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0902 1 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.0484 0.0467
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0058 0.0484 0.0439
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0659 0.0659
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0302 0.3239 0.3215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0048 0.0032
Schistosoma mansoni thyroid hormone receptor 0.0183 0.189 0.1875
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0058 0.0484 0.0467
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0041 0.0041
Onchocerca volvulus 0.0036 0.0232 0.0727
Brugia malayi Intermediate filament tail domain containing protein 0.0093 0.0882 0.0882
Schistosoma mansoni RAR-like nuclear receptor 0.0036 0.0231 0.0213

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 7.9245 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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