Detailed information for compound 1507630

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 291.387 | Formula: C20H21NO
  • H donors: 0 H acceptors: 1 LogP: 3.69 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN([C@H]1CC(=O)c2c1cccc2)[C@H]1CCc2c(C1)cccc2
  • InChi: 1S/C20H21NO/c1-21(16-11-10-14-6-2-3-7-15(14)12-16)19-13-20(22)18-9-5-4-8-17(18)19/h2-9,16,19H,10-13H2,1H3/t16-,19-/m0/s1
  • InChiKey: JDSSYTXEXBCUIC-LPHOPBHVSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cell adhesion molecule 0.0348 0.3967 0.3967
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0085 0.0515 0.0515
Schistosoma mansoni hemicentin 0.0348 0.3967 0.3967
Schistosoma mansoni factor for adipocyte differentiation 0.0275 0.301 0.301
Onchocerca volvulus 0.0073 0.0354 0.0725
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Echinococcus multilocularis tyrosine protein kinase Abl 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/ROR protein kinase 0.0158 0.1472 0.2296
Brugia malayi Furin-like cysteine rich region family protein 0.0085 0.0515 0.0803
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0085 0.0515 0.0515
Echinococcus multilocularis neuroglian 0.0433 0.5076 0.5076
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0365 0.4195 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Onchocerca volvulus 0.0085 0.0515 0.1137
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0232 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0085 0.0515 0.0803
Onchocerca volvulus 0.0073 0.0354 0.0725
Trichomonas vaginalis protein tyrosine kinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus netrin receptor unc 5 0.0084 0.0506 0.0506
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0073 0.0354 0.0354
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0073 0.0354 0.0553
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis titin 0.0348 0.3967 0.3967
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK/EGFR protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0085 0.0515 0.1074
Brugia malayi protein-tyrosine kinase 0.0085 0.0515 0.0803
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0073 0.0354 0.0354
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Plasmodium falciparum protein kinase, putative 0.0085 0.0515 0.9021
Brugia malayi Prion-like- 0.0073 0.0354 0.0553
Echinococcus multilocularis insulin growth factor binding 0.0073 0.0354 0.0354
Echinococcus multilocularis Immunoglobulin 0.0084 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis Immunoglobulin 0.0259 0.2799 0.2799
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0085 0.0515 0.0515
Echinococcus multilocularis synaptic glycoprotein sc2 0.0051 0.0072 0.0072
Onchocerca volvulus 0.0085 0.0515 0.1137
Loa Loa (eye worm) hypothetical protein 0.0084 0.0506 0.0789
Brugia malayi Heparan sulfate 0.0084 0.0506 0.0789
Schistosoma mansoni titin 0.0073 0.0354 0.0354
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Onchocerca volvulus Putative titin 0.0073 0.0354 0.0725
Echinococcus granulosus protein tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus Immunoglobulin 0.0084 0.0506 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis TK family protein kinase 0.0085 0.0515 0.1074
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 1
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0084 0.0506 0.0506
Schistosoma mansoni nephrin 0.0433 0.5076 0.5076
Loa Loa (eye worm) lethal protein 805 0.0275 0.301 0.4695
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0073 0.0354 0.0354
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0433 0.5076 0.7917
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0115 0.0906 0.1413
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0365 0.4195 1
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0197 0.0197
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0232 0.0362
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Schistosoma mansoni protein tyrosine phosphatase 0.0275 0.301 0.301
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0275 0.301 0.301
Schistosoma mansoni basigin related 0.0084 0.0506 0.0506
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Echinococcus multilocularis peroxidasin 0.0157 0.1463 0.1463
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0073 0.0354 0.0553
Brugia malayi bone morphogenetic protein type 1 receptor 0.0085 0.0515 0.0803
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0085 0.0515 0.1137
Onchocerca volvulus 0.0085 0.0515 0.1137
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0365 0.4195 1
Brugia malayi hypothetical protein 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus granulosus roundabout 2 0.0692 0.8478 0.8478
Schistosoma mansoni hypothetical protein 0.0084 0.0506 0.0506
Echinococcus granulosus tyrosine protein kinase csk 0.0085 0.0515 0.0515
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0197 0.0197
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0197 0.0304
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Onchocerca volvulus 0.0085 0.0515 0.1137
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0275 0.301 0.301
Echinococcus granulosus lachesin 0.0157 0.1463 0.1463
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Echinococcus granulosus tyrosine protein kinase otk 0.0157 0.1463 0.1463
Brugia malayi Immunoglobulin I-set domain containing protein 0.0433 0.5076 0.7917
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0344 0.3908 0.3908
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) RNA binding protein 0.0064 0.0232 0.0362
Onchocerca volvulus 0.0348 0.3967 1
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0084 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0534 0.6412 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0433 0.5076 0.5076
Echinococcus multilocularis protein kinase 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Echinococcus granulosus EG95 0.0275 0.301 0.301
Onchocerca volvulus 0.0348 0.3967 1
Leishmania major protein kinase, putative 0.0085 0.0515 0.0794
Schistosoma mansoni hypothetical protein 0.0079 0.0429 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Echinococcus granulosus geminin 0.017 0.163 0.163
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0365 0.4195 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Loa Loa (eye worm) UNCoordinated family member 0.0275 0.301 0.4695
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0275 0.301 0.4695
Echinococcus granulosus tyrosine protein kinase Srms 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Echinococcus granulosus tumor protein p63 0.0395 0.4589 0.4589
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0275 0.301 0.301
Onchocerca volvulus 0.0085 0.0515 0.1137
Onchocerca volvulus 0.0275 0.301 0.7543
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni hypothetical protein 0.0073 0.0354 0.0354
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0515 0.0515
Onchocerca volvulus 0.0275 0.301 0.7543
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.1463 0.2282
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0073 0.0354 0.0553
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0275 0.301 0.301
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) TK/CSK protein kinase 0.0085 0.0515 0.0803
Brugia malayi Protein-tyrosine phosphatase 0.0275 0.301 0.4695
Echinococcus granulosus c src tyrosine kinase 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0365 0.4195 1
Echinococcus granulosus integrin linked protein kinase 0.0085 0.0515 0.0515
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.0157 0.0157
Brugia malayi protein unc-22 0.0348 0.3967 0.6187
Echinococcus multilocularis geminin 0.017 0.163 0.163
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus tyrosine protein kinase csk 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.1463 0.2282
Echinococcus granulosus Netrin receptor DCC 0.0275 0.301 0.301
Onchocerca volvulus 0.0085 0.0515 0.1137
Onchocerca volvulus Tyrosine kinase homolog 0.0158 0.1472 0.3594
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0085 0.0515 0.0515
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0085 0.0515 0.0803
Brugia malayi Prion-like- 0.0073 0.0354 0.0553
Schistosoma mansoni basigin related 0.0084 0.0506 0.0506
Entamoeba histolytica ankyrin repeat protein 0.0085 0.0515 0.1074
Brugia malayi Fibronectin type III domain containing protein 0.0275 0.301 0.4695
Loa Loa (eye worm) disorganized muscle protein 1 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0269 0.2931 1
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Schistosoma mansoni peptidase Clp (S14 family) 0.0089 0.0563 0.0563
Brugia malayi Leucine Rich Repeat family protein 0.0073 0.0354 0.0553
Echinococcus multilocularis tyrosine protein kinase otk 0.0157 0.1463 0.1463
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0089 0.0563 1
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Brugia malayi Immunoglobulin I-set domain containing protein 0.0534 0.6412 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0058 0.0161 0.0161
Plasmodium falciparum tyrosine kinase-like protein 0.0085 0.0515 0.9021
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0158 0.1472 0.1472
Echinococcus granulosus activated cdc42 kinase 1 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/INSR protein kinase 0.0085 0.0515 0.0803
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus neuroglian 0.0433 0.5076 0.5076
Echinococcus granulosus tyrosine protein kinase ABL1 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni titin 0.0348 0.3967 0.3967
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase Srms 0.0085 0.0515 0.0515
Brugia malayi SPRY domain containing protein 0.0275 0.301 0.4695
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Echinococcus multilocularis roundabout 2 0.0692 0.8478 0.8478
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Brugia malayi Guanylyl cyclase protein 23 0.0085 0.0515 0.0803
Schistosoma mansoni titin 0.0073 0.0354 0.0354
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0515 0.1074
Mycobacterium ulcerans hypothetical protein 0.0365 0.4195 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0084 0.0506 0.0789
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0433 0.5076 0.5076
Onchocerca volvulus 0.0085 0.0515 0.1137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.1463 0.2282
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis fibronectin type III domain-containing protein 0.0275 0.301 0.301
Onchocerca volvulus Peroxidasin homolog 0.0073 0.0354 0.0725
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0085 0.0515 0.0515
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0232 0.0232
Echinococcus granulosus receptor type guanylyl cyclase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Onchocerca volvulus 0.0085 0.0515 0.1137
Echinococcus granulosus anosmin 1 0.0275 0.301 0.301
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0051 0.0072 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0354 0.0354
Onchocerca volvulus 0.0275 0.301 0.7543
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0085 0.0515 0.0515
Loa Loa (eye worm) protein kinase domain-containing protein 0.0085 0.0515 0.0803
Echinococcus granulosus ephrin type A receptor 4 A 0.0085 0.0515 0.0515
Schistosoma mansoni myosin-binding protein-related 0.0348 0.3967 0.3967
Schistosoma mansoni hypothetical protein 0.0084 0.0506 0.0506
Echinococcus granulosus Down syndrome cell adhesion molecule 0.036 0.4119 0.4119
Echinococcus granulosus Fibronectin type III 0.0275 0.301 0.301
Leishmania major hypothetical protein, conserved 0.0275 0.301 0.7036
Onchocerca volvulus 0.0058 0.0157 0.0218
Schistosoma mansoni cell adhesion molecule 0.0084 0.0506 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis kinase suppressor of Ras 1 0.0085 0.0515 0.0515
Schistosoma mansoni netrin receptor unc5 0.0084 0.0506 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni serine/threonine RGC 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis integrin linked protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0073 0.0354 0.0354
Echinococcus granulosus G1Y162 protein 0.0275 0.301 0.301
Loa Loa (eye worm) TK/FAK protein kinase 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.1463 0.2282
Brugia malayi Receptor family ligand binding region containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica cysteine surface protein, putative 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0084 0.0506 0.0506
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Brugia malayi hypothetical protein 0.0534 0.6412 1
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0348 0.3967 0.6187
Onchocerca volvulus Peroxidasin homolog 0.0073 0.0354 0.0725
Brugia malayi Calcitonin receptor-like protein seb-1 0.0115 0.0906 0.1413
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Echinococcus multilocularis tyrosine kinase 0.0085 0.0515 0.0515
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0515 0.1074
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0197 0.013
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0084 0.0506 0.0506
Echinococcus granulosus Immunoglobulin 0.0084 0.0506 0.0506
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Echinococcus multilocularis tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus activated cdc42 kinase 1 0.0085 0.0515 0.0515
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus anosmin 1 0.0275 0.301 0.301
Echinococcus granulosus leucine rich repeat containing protein 4 0.0073 0.0354 0.0354
Schistosoma mansoni cell adhesion molecule 0.0433 0.5076 0.5076
Onchocerca volvulus 0.0275 0.301 0.7543
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0275 0.301 0.301
Entamoeba histolytica receptor protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0275 0.301 0.301
Trichomonas vaginalis protein kinase atn1, putative 0.0085 0.0515 0.1074
Echinococcus granulosus insulin growth factor binding 0.0073 0.0354 0.0354
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Loa Loa (eye worm) animal heme peroxidase 0.0073 0.0354 0.0553
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Onchocerca volvulus 0.0085 0.0515 0.1137
Schistosoma mansoni hypothetical protein 0.0275 0.301 0.301
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Echinococcus granulosus peptidase Clp S14 family 0.0058 0.0161 0.0161
Onchocerca volvulus 0.0275 0.301 0.7543
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0085 0.0515 0.0515
Schistosoma mansoni cell adhesion molecule 0.0348 0.3967 0.3967
Echinococcus multilocularis anosmin 1 0.0275 0.301 0.301
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0089 0.0563 1
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 0.5
Schistosoma mansoni neuroglian 0.0433 0.5076 0.5076
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Entamoeba histolytica hypothetical protein, conserved 0.0085 0.0515 0.1074
Schistosoma mansoni basigin related 0.0084 0.0506 0.0506
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0348 0.3967 0.6187
Onchocerca volvulus Netrin receptor homolog 0.0073 0.0354 0.0725
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0084 0.0506 0.0506
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0433 0.5076 0.5076
Echinococcus granulosus nephrin 0.0348 0.3967 0.3967
Loa Loa (eye worm) hypothetical protein 0.0348 0.3967 0.6187
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0365 0.4195 1
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Echinococcus multilocularis anosmin 1 0.0275 0.301 0.301
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus Immunoglobulin 0.0259 0.2799 0.2799
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis hemicentin 1 0.0157 0.1463 0.1463
Echinococcus granulosus tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0275 0.301 0.4695
Echinococcus granulosus down syndrome cell adhesion 0.0073 0.0354 0.0354
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0348 0.3967 0.6187
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0275 0.301 0.301
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0365 0.4195 1
Plasmodium falciparum protein kinase, putative 0.0085 0.0515 0.9021
Echinococcus granulosus tyrosine protein kinase 0.0085 0.0515 0.0515
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0115 0.0906 0.1413
Trypanosoma cruzi protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus roundabout 2 0.0433 0.5076 0.5076
Brugia malayi Myb-like DNA-binding domain containing protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus granulosus tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Echinococcus multilocularis natriuretic peptide receptor 1 0.0085 0.0515 0.0515
Echinococcus granulosus insulin receptor 0.0085 0.0515 0.0515
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Leishmania major hypothetical protein, conserved 0.0085 0.0515 0.0794
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0084 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0275 0.301 0.301
Schistosoma mansoni roundabout 0.0157 0.1463 0.1463
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Schistosoma mansoni cell adhesion molecule 0.0084 0.0506 0.0506
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0259 0.2799 0.4365
Echinococcus multilocularis tyrosine protein kinase shark 0.0085 0.0515 0.0515
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0275 0.301 0.7126
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.214 0.3338
Brugia malayi TAR-binding protein 0.0064 0.0232 0.0362
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis protein tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus titin 0.0348 0.3967 0.3967
Trypanosoma brucei Pseudokinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0433 0.5076 0.5076
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Brugia malayi Pre-SET motif family protein 0.0209 0.214 0.3338
Echinococcus multilocularis protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus raf serine:threonine protein kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis epidermal growth factor receptor 0.0085 0.0515 0.0515
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Onchocerca volvulus 0.0085 0.0515 0.1137
Brugia malayi hypothetical protein 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni peroxidasin 0.0084 0.0506 0.0506
Echinococcus multilocularis transfer RNA-Phe 0.0348 0.3967 0.3967
Schistosoma mansoni hypothetical protein 0.0073 0.0354 0.0354
Echinococcus multilocularis roundabout 2 0.0433 0.5076 0.5076
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Brugia malayi ephrin receptor 1 precursor 0.0085 0.0515 0.0803
Echinococcus multilocularis ephrin type A receptor 4 A 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0084 0.0506 0.0506
Brugia malayi basement membrane proteoglycan 0.0084 0.0506 0.0789
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus titin 0.0348 0.3967 0.3967
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0433 0.5076 0.7917
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0275 0.301 0.301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni titin 0.0275 0.301 0.301
Onchocerca volvulus 0.0085 0.0515 0.1137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0433 0.5076 0.7917
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0073 0.0354 0.0553
Entamoeba histolytica receptor protein kinase, putative 0.0085 0.0515 0.1074
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0085 0.0515 0.1074
Leishmania major protein kinase, putative 0.0085 0.0515 0.0794
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Echinococcus granulosus protein kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0275 0.301 0.4695
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0051 0.0072 0.0072
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni nephrin 0.0607 0.7369 0.7369
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0157 0.1463 0.2282
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0084 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Loa Loa (eye worm) hypothetical protein 0.0051 0.0072 0.0112
Loa Loa (eye worm) hypothetical protein 0.0084 0.0506 0.0789
Loa Loa (eye worm) hypothetical protein 0.0534 0.6412 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0073 0.0354 0.0354
Schistosoma mansoni hypothetical protein 0.0084 0.0506 0.0506
Echinococcus multilocularis transfer RNA-Thr 0.0085 0.0515 0.0515
Brugia malayi Tyrosine-protein kinase PR2 0.0085 0.0515 0.0803
Brugia malayi Immunoglobulin I-set domain containing protein 0.0429 0.5025 0.7838
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0085 0.0515 0.0515
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0515 0.0515
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0085 0.0515 0.0515
Brugia malayi SRC-1 0.0085 0.0515 0.0803
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.036 0.4119 0.6424
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis Netrin receptor DCC 0.0275 0.301 0.301
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0085 0.0515 0.0803
Brugia malayi Fibronectin type III domain containing protein 0.0275 0.301 0.4695
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Toxoplasma gondii STE kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) projectin 0.0348 0.3967 0.6187
Echinococcus multilocularis roundabout 2 0.0433 0.5076 0.5076
Echinococcus granulosus tyrosine kinase 0.0085 0.0515 0.0515
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Disorganized muscle protein 1 0.0073 0.0354 0.0553
Echinococcus granulosus neuroglian 0.0332 0.3756 0.3756
Loa Loa (eye worm) hypothetical protein 0.0259 0.2799 0.4365
Plasmodium falciparum tyrosine kinase-like protein 0.0085 0.0515 0.9021
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus granulosus epidermal growth factor receptor 0.0085 0.0515 0.0515
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0515 0.0515
Loa Loa (eye worm) SRC-1 0.0085 0.0515 0.0803
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Schistosoma mansoni hypothetical protein 0.0073 0.0354 0.0354
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus granulosus twitchin 0.0332 0.3756 0.3756
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/DDR protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase Blk 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus Immunoglobulin subtype 0.0084 0.0506 0.0506
Schistosoma mansoni ephrin receptor 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0158 0.1472 0.1472
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Echinococcus granulosus tyrosine protein kinase Src42A 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Toxoplasma gondii protein kinase 0.0085 0.0515 0.1074
Onchocerca volvulus 0.0073 0.0354 0.0725
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni titin 0.0348 0.3967 0.3967
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 0.5
Loa Loa (eye worm) hypothetical protein 0.0416 0.4865 0.7588
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0365 0.4195 0.6543
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0259 0.2799 0.2799
Schistosoma mansoni cell adhesion molecule 0.0619 0.7521 0.7521
Echinococcus granulosus roundabout 2 0.0433 0.5076 0.5076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0084 0.0506 0.0789
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0085 0.0515 0.0803
Plasmodium falciparum protein kinase, putative 0.0085 0.0515 0.9021
Schistosoma mansoni titin 0.0073 0.0354 0.0354
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.036 0.4128 0.4128
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.4119 0.6424
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0275 0.301 0.4695
Brugia malayi Immunoglobulin I-set domain containing protein 0.0084 0.0506 0.0789
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis twitchin 0.0073 0.0354 0.0354
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0275 0.301 0.4695
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni factor for adipocyte differentiation 0.0275 0.301 0.301
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0051 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Echinococcus granulosus tyrosine protein kinase csk 0.0085 0.0515 0.0515
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Onchocerca volvulus 0.0275 0.301 0.7543
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0348 0.3967 0.6187
Loa Loa (eye worm) hypothetical protein 0.0084 0.0506 0.0789
Echinococcus granulosus fibroblast growth factor receptor 4 0.0085 0.0515 0.0515
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis tyrosine protein kinase HCK 0.0085 0.0515 0.0515
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0084 0.0506 0.0789
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0348 0.3967 0.3967
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0197 0.0197
Brugia malayi Lethal protein 805 0.0275 0.301 0.4695
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0259 0.2799 0.2799
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0073 0.0354 0.0553
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis titin 0.0073 0.0354 0.0354
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0515 0.1074
Brugia malayi Fibronectin type III domain containing protein 0.0534 0.6412 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0157 0.0245
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0232 0.0232
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0085 0.0515 0.1137
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0344 0.3908 0.6095
Echinococcus granulosus peroxidasin 0.0157 0.1463 0.1463
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0084 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis heat shock protein 70 0.0085 0.0515 0.0515
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0275 0.301 0.301
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Plasmodium vivax tyrosine kinase-like protein, putative 0.0085 0.0515 0.9021
Brugia malayi SH2 domain containing protein 0.0085 0.0515 0.0803
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine protein kinase pr2 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine protein kinase Src64B 0.0085 0.0515 0.0515
Brugia malayi Fibronectin type III domain containing protein 0.0275 0.301 0.4695
Brugia malayi Lethal protein 805 0.0275 0.301 0.4695
Schistosoma mansoni vesicular amine transporter 0.0259 0.2799 0.2799
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase pr2 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0232 0.0232
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0232 0.0362
Brugia malayi RNA binding protein 0.0064 0.0232 0.0362
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0084 0.0506 0.0789
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus granulosus fibronectin type III domain-containing protein 0.0275 0.301 0.301
Brugia malayi hypothetical protein 0.0275 0.301 0.4695
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Brugia malayi Immunoglobulin I-set domain containing protein 0.0084 0.0506 0.0789
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni cell adhesion molecule 0.0433 0.5076 0.5076
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0084 0.0506 0.0506
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Brugia malayi Fibronectin type III domain containing protein 0.0275 0.301 0.4695
Onchocerca volvulus 0.0073 0.0354 0.0725
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0085 0.0515 0.0515
Echinococcus granulosus natriuretic peptide receptor 1 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis activin receptor type 0.0085 0.0515 0.0515
Schistosoma mansoni titin 0.0073 0.0354 0.0354
Brugia malayi Animal haem peroxidase family protein 0.0073 0.0354 0.0553
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Echinococcus multilocularis tyrosine protein kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0157 0.1463 0.2282
Brugia malayi Prion-like- 0.0073 0.0354 0.0553
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0157 0.1463 0.1463
Echinococcus multilocularis insulin receptor 0.0085 0.0515 0.0515
Echinococcus granulosus Netrin receptor DCC 0.0275 0.301 0.301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0433 0.5076 0.7917
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0275 0.301 0.4695
Brugia malayi Immunoglobulin domain containing protein 0.0084 0.0506 0.0789
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Echinococcus multilocularis hemicentin 1 0.0157 0.1463 0.1463
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0085 0.0515 0.1074
Brugia malayi Tyrosine-protein kinase abl-1 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni hypothetical protein 0.017 0.163 0.163
Brugia malayi Peroxidasin 0.0157 0.1463 0.2282
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Echinococcus multilocularis neuroglian 0.0332 0.3756 0.3756
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis netrin receptor unc 5 0.0084 0.0506 0.0506
Trypanosoma brucei Flagellum attachment zone protein 20 0.0085 0.0515 0.1074
Onchocerca volvulus 0.0073 0.0354 0.0725
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Onchocerca volvulus 0.0073 0.0354 0.0725
Echinococcus multilocularis usherin 0.0275 0.301 0.301
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0085 0.0515 0.0515
Echinococcus multilocularis Immunoglobulin 0.0259 0.2799 0.2799
Loa Loa (eye worm) TK/ABL protein kinase 0.0085 0.0515 0.0803
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 0.0914
Schistosoma mansoni nephrin related 0.0084 0.0506 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0365 0.4195 1
Schistosoma mansoni netrin receptor unc5 0.0084 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0085 0.0515 0.0515
Onchocerca volvulus 0.0348 0.3967 1
Giardia lamblia Kinase 0.0085 0.0515 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Echinococcus multilocularis c src tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus synaptic glycoprotein sc2 0.0051 0.0072 0.0072
Onchocerca volvulus 0.0085 0.0515 0.1137
Echinococcus granulosus anosmin 1 0.0275 0.301 0.301
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Schistosoma mansoni hypothetical protein 0.0275 0.301 0.301
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0085 0.0515 0.0515
Brugia malayi Fibronectin type III domain containing protein 0.0275 0.301 0.4695
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0073 0.0354 0.0354
Echinococcus multilocularis Fibronectin, type III 0.0275 0.301 0.301
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0365 0.4195 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Schistosoma mansoni hypothetical protein 0.0085 0.0515 0.0515
Schistosoma mansoni tripartite motif protein trim9 0.0275 0.301 0.301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0158 0.1472 0.2296
Schistosoma mansoni hypothetical protein 0.017 0.163 0.163
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0085 0.0515 0.0803
Onchocerca volvulus 0.0073 0.0354 0.0725
Brugia malayi myotactin form A 0.0275 0.301 0.4695
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0089 0.0563 0.0563
Loa Loa (eye worm) myotactin form A 0.0275 0.301 0.4695
Loa Loa (eye worm) TK/ACK protein kinase 0.0085 0.0515 0.0803
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0259 0.2799 0.2799
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.1463 0.2282
Loa Loa (eye worm) hypothetical protein 0.0157 0.1463 0.2282
Echinococcus multilocularis anosmin 1 0.0275 0.301 0.301
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis protein KINase family member (kin 25) 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis STE family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine protein kinase shark 0.0085 0.0515 0.0515
Schistosoma mansoni hypothetical protein 0.0084 0.0506 0.0506
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0515 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Brugia malayi SH2 domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis cell adhesion molecule 0.0275 0.301 0.301
Onchocerca volvulus 0.0073 0.0354 0.0725
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Brugia malayi integrin-linked kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis receptor type guanylyl cyclase 0.0085 0.0515 0.0515
Schistosoma mansoni hypothetical protein 0.0073 0.0354 0.0354
Loa Loa (eye worm) TK/ALK protein kinase 0.0085 0.0515 0.0803
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0051 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus low density lipoprotein receptor ldl 0.0084 0.0506 0.0506
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Giardia lamblia Kinase, NEK 0.0085 0.0515 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni factor for adipocyte differentiation 0.0275 0.301 0.301
Echinococcus granulosus defective proboscis extension response 0.0259 0.2799 0.2799
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0084 0.0506 0.0789
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0084 0.0506 0.0506
Echinococcus granulosus tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0433 0.5076 0.5076
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0073 0.0354 0.0553
Entamoeba histolytica ankyrin repeat protein 0.0085 0.0515 0.1074
Plasmodium vivax protein kinase, putative 0.0085 0.0515 0.9021
Onchocerca volvulus 0.0275 0.301 0.7543
Brugia malayi hypothetical protein 0.0085 0.0515 0.0803
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Onchocerca volvulus 0.0275 0.301 0.7543
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0085 0.0515 0.1074
Echinococcus granulosus tyrosine protein kinase Lyn 0.0085 0.0515 0.0515
Echinococcus multilocularis FL cytokine receptor 0.0085 0.0515 0.0515
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0275 0.301 0.7126
Onchocerca volvulus 0.0275 0.301 0.7543
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK/Met protein kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0433 0.5076 0.5076
Echinococcus granulosus kinase suppressor of Ras 1 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0085 0.0515 0.0515
Giardia lamblia Kinase, NEK 0.0085 0.0515 1
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus usherin 0.0275 0.301 0.301
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0563 0.1191
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Echinococcus multilocularis lachesin 0.0157 0.1463 0.1463
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0515 0.1074
Schistosoma mansoni cell adhesion molecule 0.0073 0.0354 0.0354
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0515 0.0515
Trichomonas vaginalis set domain proteins, putative 0.0238 0.2519 0.5935
Echinococcus multilocularis titin 0.0073 0.0354 0.0354
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Schistosoma mansoni tyrosine protein kinase 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis raf serine:threonine protein kinase 0.0085 0.0515 0.0515
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Brugia malayi basement membrane proteoglycan precursor 0.0084 0.0506 0.0789
Schistosoma mansoni septate junction protein 0.0084 0.0506 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni septate junction protein 0.0084 0.0506 0.0506
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0089 0.0563 0.0563
Loa Loa (eye worm) TK/RYK protein kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) one IG domain family member 0.0073 0.0354 0.0553
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Schistosoma mansoni cell adhesion molecule 0.0157 0.1463 0.1463
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0515 0.0803
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0085 0.0515 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.301 0.7126
Loa Loa (eye worm) hypothetical protein 0.0259 0.2799 0.4365
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0157 0.1463 0.1463
Entamoeba histolytica hypothetical protein 0.0085 0.0515 0.1074
Echinococcus multilocularis activated cdc42 kinase 1 0.0085 0.0515 0.0515
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Echinococcus granulosus titin 0.0073 0.0354 0.0354
Echinococcus multilocularis Fibronectin type III domain containing protein 0.0275 0.301 0.301
Brugia malayi Probable ClpP-like protease 0.0089 0.0563 0.0878
Echinococcus multilocularis epidermal growth factor receptor 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0051 0.0072 0.0112
Brugia malayi C-terminal src kinase protein 1 0.0085 0.0515 0.0803
Echinococcus granulosus retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0275 0.301 0.301
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.036 0.4119 0.4119
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0429 0.5025 0.7838
Brugia malayi Raf kinase 0.0085 0.0515 0.0803
Loa Loa (eye worm) CAMK protein kinase 0.0348 0.3967 0.6187
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0416 0.4865 0.7588
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0275 0.301 0.4695
Brugia malayi Synaptic glycoprotein SC2 0.0051 0.0072 0.0112
Schistosoma mansoni septate junction protein 0.0157 0.1463 0.1463
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0232 0.0232
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.3967 0.3967
Brugia malayi Immunoglobulin domain containing protein 0.0084 0.0506 0.0789
Onchocerca volvulus 0.0085 0.0515 0.1137
Echinococcus granulosus hemicentin 1 0.0157 0.1463 0.1463
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0085 0.0515 0.1074
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0085 0.0515 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0085 0.0515 0.0515
Echinococcus granulosus insulin growth factor 1 receptor beta 0.036 0.4128 0.4128
Brugia malayi kettin 0.0073 0.0354 0.0553
Brugia malayi Prion-like- 0.0157 0.1463 0.2282
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Schistosoma mansoni hypothetical protein 0.0073 0.0354 0.0354
Echinococcus multilocularis Netrin receptor DCC 0.0275 0.301 0.301
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0085 0.0515 0.1074
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0563 0.1191
Schistosoma mansoni ephrin receptor 0.036 0.4128 0.4128
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553
Loa Loa (eye worm) hypothetical protein 0.0365 0.4195 0.6543
Onchocerca volvulus 0.0085 0.0515 0.1137
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0085 0.0515 0.0803
Echinococcus granulosus titin 0.0073 0.0354 0.0354
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Echinococcus granulosus cell adhesion molecule 0.0275 0.301 0.301
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Brugia malayi latrophilin 2 splice variant baaae 0.0079 0.0429 0.0669
Schistosoma mansoni protein tyrosine kinase 0.0085 0.0515 0.0515
Schistosoma mansoni titin 0.0073 0.0354 0.0354
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0232 0.0232
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0073 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0089 0.0563 0.0878
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0515 0.1074
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Loa Loa (eye worm) hypothetical protein 0.0348 0.3967 0.6187
Loa Loa (eye worm) TK protein kinase 0.0158 0.1472 0.2296
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 0.0914
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Plasmodium vivax tyrosine kinase-like protein, putative 0.0085 0.0515 0.9021
Echinococcus granulosus basement membrane specific heparan sulfate 0.0084 0.0506 0.0506
Loa Loa (eye worm) TK protein kinase 0.0085 0.0515 0.0803
Echinococcus granulosus Fibronectin type III domain containing protein 0.0275 0.301 0.301
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Loa Loa (eye worm) LAD-2 short isoform 0.0084 0.0506 0.0789
Schistosoma mansoni hypothetical protein 0.0084 0.0506 0.0506
Schistosoma mansoni hypothetical protein 0.0348 0.3967 0.3967
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis titin 0.0073 0.0354 0.0354
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Trypanosoma brucei Fibronectin type III domain containing protein, putative 0.0275 0.301 0.7126
Echinococcus granulosus epidermal growth factor receptor 0.0085 0.0515 0.0515
Schistosoma mansoni titin 0.0157 0.1463 0.1463
Loa Loa (eye worm) hypothetical protein 0.0433 0.5076 0.7917
Echinococcus granulosus tar DNA binding protein 0.0064 0.0232 0.0232
Trypanosoma brucei protein kinase, putative 0.0085 0.0515 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Brugia malayi Immunoglobulin domain containing protein 0.0084 0.0506 0.0789
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.1463 0.2282
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0563 0.5
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Trypanosoma cruzi protein kinase, putative 0.0085 0.0515 0.1074
Loa Loa (eye worm) serine/threonine protein kinase 0.0085 0.0515 0.0803
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.3967 0.6187
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Schistosoma mansoni nephrin related 0.0073 0.0354 0.0354
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0084 0.0506 0.0506
Echinococcus granulosus contactin 0.0433 0.5076 0.5076
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0197 0.0197
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0232 0.0232
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0157 0.1463 0.3572
Loa Loa (eye worm) hypothetical protein 0.0073 0.0354 0.0553
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Onchocerca volvulus 0.0238 0.2519 0.6282
Loa Loa (eye worm) TK/EPH protein kinase 0.0085 0.0515 0.0803
Brugia malayi hypothetical protein 0.0084 0.0506 0.0789
Brugia malayi Protein kinase domain containing protein 0.0085 0.0515 0.0803
Brugia malayi myotactin form B 0.0275 0.301 0.4695
Echinococcus multilocularis Immunoglobulin 0.0084 0.0506 0.0506
Echinococcus granulosus activin receptor type 0.0085 0.0515 0.0515
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Schistosoma mansoni hypothetical protein 0.0084 0.0506 0.0506
Toxoplasma gondii protein kinase domain-containing protein 0.0085 0.0515 0.1074
Schistosoma mansoni tyrosine kinase 0.0242 0.2581 0.2581
Loa Loa (eye worm) hypothetical protein 0.0275 0.301 0.4695
Schistosoma mansoni hypothetical protein 0.0073 0.0354 0.0354
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0085 0.0515 0.0803
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Echinococcus multilocularis Phosphotidylinositol phosphatase PTPRQ 0.0275 0.301 0.301
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0515 0.1074
Onchocerca volvulus 0.0275 0.301 0.7543
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0115 0.0906 0.1413
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Schistosoma mansoni tyrosine kinase 0.0085 0.0515 0.0515
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0085 0.0515 0.1074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Echinococcus multilocularis tumor protein p63 0.0395 0.4589 0.4589
Echinococcus granulosus retinal guanylyl cyclase 2 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Echinococcus granulosus tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Echinococcus multilocularis Immunoglobulin subtype 0.0084 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0085 0.0515 0.0803
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0515 0.1074
Giardia lamblia Protein 21.1 0.0085 0.0515 1
Echinococcus multilocularis titin 0.0275 0.301 0.301
Echinococcus granulosus tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0534 0.6412 1
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Loa Loa (eye worm) hypothetical protein 0.0079 0.0429 0.0669
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0085 0.0515 0.0515
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0085 0.0515 0.0515
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0085 0.0515 0.0515
Echinococcus granulosus tyrosine protein kinase HCK 0.0085 0.0515 0.0515
Echinococcus multilocularis down syndrome cell adhesion 0.0073 0.0354 0.0354
Schistosoma mansoni septate junction protein 0.0157 0.1463 0.1463
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0085 0.0515 0.0515
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0515 0.1074
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0515 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0515 0.1074
Schistosoma mansoni slit 0.0073 0.0354 0.0354
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0085 0.0515 0.0803
Echinococcus multilocularis 0.0073 0.0354 0.0354
Echinococcus granulosus titin 0.0073 0.0354 0.0354
Echinococcus granulosus tyrosine protein kinase Blk 0.0085 0.0515 0.0515
Schistosoma mansoni protein kinase 0.0085 0.0515 0.0515
Onchocerca volvulus 0.0275 0.301 0.7543
Onchocerca volvulus 0.0085 0.0515 0.1137
Entamoeba histolytica protein kinase, putative 0.0085 0.0515 0.1074
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0085 0.0515 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0354 0.0553

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 40 % Inhibition of A23187-induced histamine release in porcine peritoneal mast cells at 20 uM ChEMBL. 21273065
Inhibition (functional) = 54 % Inhibition of concanavalin A-induced histamine release in rat peritoneal mast cells at 20 uM ChEMBL. 21273065
Inhibition (functional) = 68 % Inhibition of A23187-induced histamine release in rat peritoneal mast cells at 20 uM ChEMBL. 21273065
Inhibition (functional) = 73 % Inhibition of IgE-induced PCA reaction in albino Swiss mouse at 3 mg/kg administered intradermally ChEMBL. 21273065
Inhibition (functional) = 79 % Inhibition of vancomycin-induced histamine release in rat peritoneal mast cells at 20 uM ChEMBL. 21273065
Inhibition (functional) = 86 % Inhibition of anti-IgE-induced histamine release in porcine lung mast cells at 20 uM ChEMBL. 21273065
Inhibition (functional) = 107 % Inhibition of compound 48/80-induced histamine release in rat peritoneal mast cells at 20 uM ChEMBL. 21273065

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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