Detailed information for compound 1763400

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 255.784 | Formula: C14H22ClNO
  • H donors: 2 H acceptors: 1 LogP: 3.14 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H]1CCCC[C@@H]1N[C@@H](c1ccccc1)C.Cl
  • InChi: 1S/C14H21NO.ClH/c1-11(12-7-3-2-4-8-12)15-13-9-5-6-10-14(13)16;/h2-4,7-8,11,13-16H,5-6,9-10H2,1H3;1H/t11-,13+,14-;/m1./s1
  • InChiKey: BCCOQJSGYYMLLQ-UNZLNSEESA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi NIMA-related kinase, putative 0.0023 0.0061 0.0272
Onchocerca volvulus 0.0249 0.239 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0233 0.0229
Schistosoma mansoni cyclin d 0.0018 0.0009 0.001
Brugia malayi hypothetical protein 0.0018 0.0009 0.0004
Trypanosoma brucei cyclin 9 0.0018 0.0009 0.004
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.002 0.003 0.0134
Onchocerca volvulus 0.0073 0.0579 0.2408
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Trypanosoma cruzi cyclin 6, putative 0.0073 0.0579 0.2581
Echinococcus granulosus Cyclin L1 0.0018 0.0009 0.001
Trichomonas vaginalis cyclin A, putative 0.0073 0.0579 0.2408
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0023 0.0061 0.0272
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Onchocerca volvulus 0.0027 0.0109 0.0436
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.029 0.0285
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.002 0.003 0.0134
Schistosoma mansoni oxysterol-binding protein 1 0.0017 0.0005 0.0005
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0233 0.0264
Leishmania major hypothetical protein, conserved 0.0017 0.0005 0.0021
Brugia malayi hypothetical protein 0.0018 0.0009 0.0004
Onchocerca volvulus 0.0038 0.0216 0.0887
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus multilocularis pleckstrin y domain containing family A 0.0017 0.0005 0.0005
Echinococcus multilocularis dynamin 1 0.0017 0.0005 0.0005
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0055 0.0396 0.1767
Plasmodium falciparum cyclin 1 0.0018 0.0009 0.004
Schistosoma mansoni cyclins 0.0073 0.0579 0.0655
Loa Loa (eye worm) cyclin domain-containing protein 0.0018 0.0009 0.0004
Onchocerca volvulus 0.0027 0.0109 0.0436
Onchocerca volvulus 0.0027 0.0109 0.0436
Trypanosoma brucei mitotic cyclin 0.0018 0.0009 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0233 0.096
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.002 0.003 0.0134
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0216 0.0212
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.002 0.003 0.0134
Schistosoma mansoni hypothetical protein 0.0036 0.0195 0.0221
Brugia malayi Tyrosine-protein kinase abl-1 0.0043 0.027 0.0265
Entamoeba histolytica hypothetical protein 0.0023 0.0061 0.0272
Mycobacterium ulcerans lipase LipD 0.0038 0.0216 0.023
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0055 0.0396 1
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.002 0.003 0.0134
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0233 0.0264
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0005 0.0005
Trypanosoma cruzi cdc2-related kinase 3 0.0181 0.1691 0.7538
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0216 0.0887
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0017 0.0005 0.0021
Entamoeba histolytica cyclin, domain containing protein 0.0018 0.0009 0.004
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0233 0.026
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0233 0.0229
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0138 0.0153
Echinococcus granulosus tyrosine protein kinase ABL1 0.0027 0.0109 0.0121
Echinococcus granulosus cpg binding protein 0.0032 0.0155 0.0173
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0017 0.0005 0.00000005655
Echinococcus granulosus tyrosine kinase 0.0027 0.0109 0.0121
Toxoplasma gondii hypothetical protein 0.0017 0.0005 0.0021
Onchocerca volvulus 0.0027 0.0109 0.0436
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Schistosoma mansoni rho gtpase activating protein 0.0017 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Schistosoma mansoni protein kinase 0.0234 0.2243 0.2539
Echinococcus multilocularis tyrosine protein kinase Blk 0.0027 0.0109 0.0121
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0023 0.0061 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0233 0.096
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.027 0.03
Echinococcus multilocularis cyclin dependent kinase 1 0.0181 0.1691 0.188
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0009 0.0019
Trypanosoma brucei acetyl-CoA carboxylase 0.0145 0.1321 0.5888
Giardia lamblia Cyclin A 0.0073 0.0579 0.2551
Brugia malayi Protein kinase domain containing protein 0.0027 0.0109 0.0104
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0025 0.0082 0.0328
Echinococcus granulosus expressed protein 0.0039 0.0233 0.026
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0018 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.0175 0.1634 0.1631
Echinococcus granulosus tyrosine protein kinase Srms 0.0027 0.0109 0.0121
Echinococcus multilocularis DCC interacting protein 13 beta 0.0017 0.0005 0.0005
Schistosoma mansoni cyclin B3 0.0073 0.0579 0.0655
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0216 0.023
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0017 0.0005 0.0005
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.002 0.003 0.0033
Echinococcus granulosus Pleckstrin y 0.0017 0.0005 0.0005
Echinococcus granulosus cyclin y 0.0018 0.0009 0.001
Schistosoma mansoni cyclin G 0.0018 0.0009 0.001
Toxoplasma gondii phosphatidylinositol transfer protein 0.0017 0.0005 0.0021
Leishmania major cyclin 9, putative 0.0018 0.0009 0.004
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0138 0.0133
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0216 0.023
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0023 0.0061 0.0272
Trypanosoma cruzi cyclin 9, putative 0.0018 0.0009 0.004
Brugia malayi Cyclin, N-terminal domain containing protein 0.0073 0.0579 0.0575
Trichomonas vaginalis cyclin D, putative 0.0073 0.0579 0.2408
Schistosoma mansoni tyrosine kinase 0.0043 0.027 0.0305
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0055 0.0396 0.1767
Echinococcus multilocularis cyclin y 0.0018 0.0009 0.001
Toxoplasma gondii Oxysterol-binding protein 0.0017 0.0005 0.0021
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Plasmodium vivax SET domain protein, putative 0.0032 0.0157 0.0679
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0017 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Btk29A 0.089 0.8994 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0032 0.0154 0.0149
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0017 0.0005 0.0021
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0017 0.0005 0.0021
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0018 0.0009 0.0004
Trypanosoma cruzi PH domain containing protein, putative 0.0017 0.0005 0.0021
Entamoeba histolytica cell division protein kinase 2, putative 0.0181 0.1691 0.7538
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0216 0.023
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Loa Loa (eye worm) hypothetical protein 0.0039 0.0233 0.0229
Echinococcus granulosus cyclin dependent kinase 1 0.0181 0.1691 0.188
Trichomonas vaginalis AGC family protein kinase 0.0234 0.2243 0.9385
Trypanosoma brucei aurora B kinase 0.0234 0.2243 1
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.145 0.6059
Trypanosoma brucei PH domain containing protein, putative 0.0017 0.0005 0.0021
Loa Loa (eye worm) AUR protein kinase 0.0234 0.2243 0.2239
Echinococcus granulosus cyclin k 0.0018 0.0009 0.001
Entamoeba histolytica hypothetical protein 0.0023 0.0061 0.0272
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0043 0.027 0.03
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0145 0.1321 0.1468
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0366 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0385 0.3795 0.4296
Echinococcus multilocularis cyclin dependent kinase 5 0.0181 0.1691 0.188
Onchocerca volvulus 0.003 0.0138 0.0558
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0483 0.0537
Trichomonas vaginalis AGC family protein kinase 0.0234 0.2243 0.9385
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0233 0.0264
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Echinococcus granulosus calcium dependent secretion activator 1 0.0017 0.0005 0.0005
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0233 0.026
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0023 0.0061 0.0272
Mycobacterium leprae Probable lipase LipE 0.0038 0.0216 0.508
Echinococcus granulosus cyclins 0.0073 0.0579 0.0644
Echinococcus multilocularis oxysterol binding protein 1 0.0017 0.0005 0.0005
Brugia malayi beta-lactamase family protein 0.0038 0.0216 0.0212
Brugia malayi P38 map kinase family protein 2 0.0208 0.1967 0.1963
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus multilocularis cytohesin 1 0.0017 0.0005 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0009 0.002
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0233 0.0264
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0212
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.002 0.003 0.0033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0216 0.023
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0061 0.0272
Brugia malayi Pre-SET motif family protein 0.0032 0.0157 0.0152
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Giardia lamblia Hypothetical protein 0.0073 0.0579 0.2551
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0233 0.096
Trichomonas vaginalis cyclins, putative 0.0073 0.0579 0.2408
Trichomonas vaginalis cyclin B, putative 0.0073 0.0579 0.2408
Echinococcus multilocularis c src tyrosine kinase 0.0043 0.027 0.03
Trypanosoma brucei mitotic cyclin 6 0.0073 0.0579 0.2581
Echinococcus granulosus NCK adaptor protein 0.0032 0.0154 0.0171
Leishmania major cyclin 0.0073 0.0579 0.2581
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0023 0.0061 0.0272
Schistosoma mansoni vav2 0.0033 0.017 0.0192
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0216 0.0887
Echinococcus granulosus oxysterol binding protein 3 0.0017 0.0005 0.0005
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0027 0.0109 0.0121
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.0233 0.026
Brugia malayi SH2 domain containing protein 0.0027 0.0109 0.0104
Loa Loa (eye worm) TK protein kinase 0.0027 0.0109 0.0104
Leishmania major hypothetical protein, conserved 0.0017 0.0005 0.0021
Brugia malayi Protein kinase domain containing protein 0.0027 0.0109 0.0104
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0055 0.0396 0.0452
Onchocerca volvulus Huntingtin homolog 0.0128 0.1149 0.4799
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0073 0.0579 0.0575
Echinococcus granulosus beta 1 syntrophin 0.0017 0.0005 0.0005
Entamoeba histolytica hypothetical protein, conserved 0.0017 0.0005 0.0021
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0017 0.0005 0.0005
Echinococcus multilocularis Ras associated and pleckstrin y 0.0017 0.0005 0.0005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus multilocularis Oxysterol binding protein 11 0.0017 0.0005 0.0005
Entamoeba histolytica cyclin, domain containing protein 0.0018 0.0009 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.145 0.6059
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0027 0.0109 0.0121
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.0233 0.026
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0033 0.017 0.0165
Brugia malayi serine/threonine-protein kinase 6 0.0234 0.2243 0.2239
Toxoplasma gondii hypothetical protein 0.0017 0.0005 0.0021
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0043 0.027 0.03
Echinococcus granulosus cyclin 0.0018 0.0009 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0321 0.0357
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0233 0.0229
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0043 0.027 0.03
Echinococcus granulosus tyrosine protein kinase Lyn 0.0048 0.0326 0.0362
Schistosoma mansoni goodpasture antigen-binding protein 0.0017 0.0005 0.0005
Onchocerca volvulus Cyclin L homolog 0.0018 0.0009 0.0019
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0321 0.0357
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0212
Schistosoma mansoni Cyclin fold protein 0.0018 0.0009 0.001
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0017 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0511 0.0579
Schistosoma mansoni zinc finger protein 0.0017 0.0005 0.0005
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0032 0.0154 0.0149
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Schistosoma mansoni growth factor receptor-bound protein 0.0032 0.0154 0.0174
Leishmania major protein kinase, putative 0.0234 0.2243 1
Trypanosoma brucei cyclin 3 0.0018 0.0009 0.004
Brugia malayi cyclin fold protein 1 variant b 0.0018 0.0009 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Echinococcus multilocularis rac serine:threonine kinase 0.0023 0.0061 0.0068
Echinococcus granulosus pleckstrin y domain containing family A 0.0017 0.0005 0.0005
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0017 0.0005 0.0005
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0233 0.0229
Schistosoma mansoni adapter molecule crk 0.0032 0.0154 0.0174
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.0009 0.0004
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0023 0.0061 0.0236
Leishmania major folate/biopterin transporter, putative 0.0023 0.0061 0.0272
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.0233 0.026
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0233 0.0264
Entamoeba histolytica PH domain containing protein 0.0017 0.0005 0.0021
Trichomonas vaginalis cyclin B, putative 0.0073 0.0579 0.2408
Echinococcus granulosus cyclins 0.0018 0.0009 0.001
Schistosoma mansoni growth factor receptor-bound protein 0.0032 0.0154 0.0174
Entamoeba histolytica p21-activated kinase 0.0023 0.0061 0.0272
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.027 0.03
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0055 0.0396 0.0449
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0483 0.0559
Loa Loa (eye worm) cyclin domain-containing protein 0.0018 0.0009 0.0004
Trichomonas vaginalis cyclins, putative 0.0073 0.0579 0.2408
Trypanosoma brucei cdc2-related kinase 3 0.0181 0.1691 0.7538
Entamoeba histolytica cyclin C, putative 0.0018 0.0009 0.004
Leishmania major serine/threonine-protein kinase a, putative 0.0023 0.0061 0.0272
Schistosoma mansoni hypothetical protein 0.0177 0.1656 0.1874
Onchocerca volvulus 0.0032 0.0157 0.0637
Trypanosoma cruzi aurora B kinase, putative 0.0234 0.2243 1
Schistosoma mansoni serine/threonine protein kinase 0.0385 0.3795 0.4296
Echinococcus multilocularis tyrosine kinase 0.0027 0.0109 0.0121
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0017 0.0005 0.0021
Loa Loa (eye worm) hypothetical protein 0.0128 0.1149 0.1145
Schistosoma mansoni acetyl-CoA carboxylase 0.0145 0.1321 0.1495
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0157 0.0177
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0483 0.0547
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0017 0.0005 0.0021
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0216 0.024
Schistosoma mansoni tyrosine kinase 0.0043 0.027 0.0305
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0208 0.1967 0.8771
Loa Loa (eye worm) hypothetical protein 0.0039 0.0233 0.0229
Mycobacterium tuberculosis Conserved protein 0.0038 0.0216 0.023
Schistosoma mansoni tyrosine kinase 0.0043 0.027 0.0305
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0023 0.0061 0.0272
Onchocerca volvulus 0.0038 0.0216 0.0887
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0483 0.0559
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0043 0.027 0.03
Schistosoma mansoni zinc finger protein 0.0017 0.0005 0.0005
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0023 0.0061 0.0272
Brugia malayi Protein kinase domain containing protein 0.0023 0.0061 0.0056
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0216 0.024
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0145 0.1321 0.5888
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Echinococcus multilocularis tyrosine protein kinase Srms 0.0027 0.0109 0.0121
Onchocerca volvulus 0.0018 0.0009 0.0019
Brugia malayi serine/threonine kinase 12 0.0234 0.2243 0.2239
Giardia lamblia Kinase, CMGC CDK 0.0181 0.1691 0.7528
Echinococcus multilocularis mitogen activated protein kinase 11 0.0208 0.1967 0.2187
Echinococcus granulosus G1:S specific cyclin D1 0.0018 0.0009 0.001
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0017 0.0005 0.0005
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0181 0.1691 0.188
Echinococcus multilocularis mitogen activated protein kinase 14 0.0208 0.1967 0.2187
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Entamoeba histolytica hypothetical protein 0.0017 0.0005 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.029 0.0328
Echinococcus multilocularis aurora kinase A 0.0234 0.2243 0.2494
Trypanosoma cruzi CYC2-like cyclin, putative 0.0073 0.0579 0.2581
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0145 0.1321 0.5888
Toxoplasma gondii cyclin dependent kinase binding protein 0.0018 0.0009 0.004
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0017 0.0005 0.0005
Plasmodium vivax cyclin 4, putative 0.0018 0.0009 0.002
Trypanosoma cruzi mitotic cyclin, putative 0.0018 0.0009 0.004
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0018 0.0009 0.002
Echinococcus multilocularis cyclin A3 4 0.0018 0.0009 0.001
Trichomonas vaginalis set domain proteins, putative 0.0249 0.239 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0049 0.0219
Trichomonas vaginalis cyclin B, putative 0.0073 0.0579 0.2408
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0427 0.1902
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0017 0.0005 0.0021
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0017 0.0005 0.0005
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.0233 0.096
Echinococcus granulosus tyrosine kinase 0.0027 0.0109 0.0121
Giardia lamblia Aurora kinase 0.0234 0.2243 1
Trichomonas vaginalis cyclins, putative 0.0018 0.0009 0.0019
Loa Loa (eye worm) CYL-1 protein 0.0018 0.0009 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0157 0.0177
Echinococcus granulosus cyclin b3 0.0073 0.0579 0.0644
Trypanosoma brucei protein kinase, putative 0.0023 0.0061 0.0272
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0055 0.0396 0.1767
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0009 0.004
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.002 0.003 0.0034
Entamoeba histolytica hypothetical protein 0.0039 0.0233 0.1041
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0233 0.026
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.089 0.8994 1
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Loa Loa (eye worm) cyclin domain-containing protein 0.0987 1 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0483 0.2152
Echinococcus multilocularis Cyclin L1 0.0018 0.0009 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0321 0.0357
Echinococcus multilocularis pdz domain containing protein 0.0017 0.0005 0.0005
Echinococcus granulosus cyclins 0.0073 0.0579 0.0644
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0233 0.026
Echinococcus granulosus cyclins 0.0073 0.0579 0.0644
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0366 0.0361
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0195 0.0191
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0027 0.0109 0.0485
Plasmodium vivax cyclin homologue, putative 0.0018 0.0009 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0321 0.0357
Schistosoma mansoni tyrosine kinase 0.0043 0.027 0.0305
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Echinococcus multilocularis Pleckstrin y 0.0017 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Trichomonas vaginalis cyclins, putative 0.0018 0.0009 0.0019
Echinococcus granulosus tyrosine protein kinase shark 0.0027 0.0109 0.0121
Trichomonas vaginalis cyclins, putative 0.0073 0.0579 0.2408
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0061 0.0069
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0043 0.027 0.0305
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trichomonas vaginalis AGC family protein kinase 0.0234 0.2243 0.9385
Entamoeba histolytica PH domain containing protein 0.0017 0.0005 0.0021
Echinococcus granulosus tyrosine protein kinase Blk 0.0027 0.0109 0.0121
Trypanosoma cruzi PH domain containing protein, putative 0.0017 0.0005 0.0021
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0017 0.0005 0.0021
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Schistosoma mansoni pyruvate carboxylase 0.0055 0.0396 0.0449
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.0233 0.026
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0017 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0321 0.0364
Echinococcus multilocularis cyclin B3 1 0.0073 0.0579 0.0644
Loa Loa (eye worm) SRC-1 0.0043 0.027 0.0265
Brugia malayi Protein kinase domain containing protein 0.0027 0.0109 0.0104
Loa Loa (eye worm) AUR protein kinase 0.0234 0.2243 0.2239
Trypanosoma cruzi Protein kinase B 0.0023 0.0061 0.0272
Echinococcus granulosus cyclins 0.0073 0.0579 0.0644
Echinococcus granulosus geminin 0.0177 0.1656 0.1841
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0216 0.023
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0073 0.0579 0.0644
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0055 0.0396 0.0441
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0233 0.026
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0497 0.0562
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0157 0.0174
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0216 0.0887
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.027 0.03
Schistosoma mansoni hypothetical protein 0.0177 0.1656 0.1874
Trichomonas vaginalis cyclin D, putative 0.0018 0.0009 0.0019
Trypanosoma cruzi PH domain containing protein, putative 0.0017 0.0005 0.0021
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0208 0.1967 0.1963
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0321 0.0364
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0055 0.0396 0.1767
Toxoplasma gondii ABC1 family protein 0.0038 0.0216 0.0964
Echinococcus granulosus aurora kinase A 0.0234 0.2243 0.2494
Brugia malayi hypothetical protein 0.0027 0.0109 0.0104
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Mycobacterium ulcerans beta-lactamase 0.0038 0.0216 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0009 0.0019
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Toxoplasma gondii hypothetical protein 0.0055 0.0398 0.1773
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0216 0.0964
Brugia malayi Sex muscle abnormal protein 5 0.0032 0.0154 0.0149
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Loa Loa (eye worm) hypothetical protein 0.0039 0.0233 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0032 0.0157 0.0152
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus granulosus oxysterol binding protein 1 0.0017 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0234 0.2243 0.9385
Echinococcus granulosus cyclin A3 4 0.0018 0.0009 0.001
Echinococcus granulosus cyclin B 0.0073 0.0579 0.0644
Brugia malayi hypothetical protein 0.0039 0.0233 0.0229
Trichomonas vaginalis cyclin B, putative 0.0018 0.0009 0.0019
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0018 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.1691 0.707
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0216 0.0212
Onchocerca volvulus 0.0038 0.0216 0.0887
Mycobacterium ulcerans short chain dehydrogenase 0.0806 0.813 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.027 0.03
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.0009 0.0004
Onchocerca volvulus Cyclin L homolog 0.0018 0.0009 0.0019
Echinococcus multilocularis calcium dependent secretion activator 1 0.0017 0.0005 0.0005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0216 0.023
Echinococcus multilocularis mitogen activated protein kinase 14 0.0208 0.1967 0.2187
Echinococcus granulosus cyclin B3 1 0.0073 0.0579 0.0644
Echinococcus multilocularis cyclin t1 0.0018 0.0009 0.001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0233 0.0264
Onchocerca volvulus Glucosylceramidase homolog 0.0149 0.1367 0.5712
Echinococcus multilocularis oxysterol binding protein 9 0.0017 0.0005 0.0005
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.0233 0.0229
Schistosoma mansoni cyclin l 0.0018 0.0009 0.001
Mycobacterium tuberculosis Probable oxidoreductase 0.0806 0.813 1
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0055 0.0396 0.0449
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0128 0.1149 0.1145
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0233 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0233 0.096
Entamoeba histolytica cyclin, putative 0.0073 0.0579 0.2581
Trichomonas vaginalis cyclin B, putative 0.0018 0.0009 0.0019
Trypanosoma cruzi NIMA-related kinase, putative 0.0023 0.0061 0.0272
Loa Loa (eye worm) hypothetical protein 0.0033 0.017 0.0165
Trichomonas vaginalis centaurin/arf, putative 0.0017 0.0005 0.00000005655
Echinococcus granulosus dnaJ subfamily B 0.0428 0.424 0.4714
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.002 0.003 0.0134
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0017 0.0005 0.0021
Echinococcus multilocularis cyclin k 0.0018 0.0009 0.001
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Entamoeba histolytica cyclin, putative 0.0073 0.0579 0.2581
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0233 0.096
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0017 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0055 0.0396 1
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0073 0.0579 0.2581
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0055 0.0396 0.0452
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.0009 0.0004
Echinococcus multilocularis expressed protein 0.0039 0.0233 0.026
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0228 0.2173 0.217
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0483 0.0547
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Leishmania major mitotic cyclin, putative 0.0018 0.0009 0.004
Echinococcus multilocularis beta 1 syntrophin 0.0017 0.0005 0.0005
Brugia malayi Cyclin C 0.0018 0.0009 0.0004
Echinococcus granulosus cyclin G2 0.0018 0.0009 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0018 0.0009 0.001
Onchocerca volvulus 0.0027 0.0109 0.0436
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0212
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Loa Loa (eye worm) beta-lactamase 0.0038 0.0216 0.0212
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0233 0.0264
Chlamydia trachomatis biotin carboxylase 0.005 0.0344 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.0208 0.1967 0.2187
Echinococcus granulosus GRB2 associated binding protein 3 0.0017 0.0005 0.0005
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0017 0.0005 0.0005
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0234 0.2243 1
Schistosoma mansoni cyclin G2 0.0018 0.0009 0.001
Echinococcus granulosus growth factor receptor bound protein 2 0.0032 0.0154 0.0171
Echinococcus granulosus cyclin dependent kinase 5 0.0181 0.1691 0.188
Echinococcus granulosus cyclin t1 0.0018 0.0009 0.001
Brugia malayi Variant SH3 domain containing protein 0.0033 0.017 0.0165
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Brugia malayi Protein kinase domain containing protein 0.0027 0.0109 0.0104
Trypanosoma cruzi PH domain containing protein, putative 0.0017 0.0005 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0228 0.2173 0.9094
Entamoeba histolytica hypothetical protein 0.0039 0.0233 0.1041
Leishmania major acetyl-CoA carboxylase, putative 0.0145 0.1321 0.5888
Brugia malayi serine/threonine protein kinase 6 0.0234 0.2243 0.2239
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0017 0.0005 0.0021
Loa Loa (eye worm) RNA binding protein 0.0066 0.0511 0.0507
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0055 0.0396 0.1767
Onchocerca volvulus Protein CNPPD1 homolog 0.0018 0.0009 0.0019
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0033 0.0166 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0216 0.0964
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.2243 0.2539
Echinococcus multilocularis Rho GTPase activating protein 24 0.0017 0.0005 0.0005
Giardia lamblia G2/mitotic-specific cyclin B 0.0073 0.0579 0.2551
Schistosoma mansoni oxysterol-binding protein 1 0.0017 0.0005 0.0005
Brugia malayi Carboxyl transferase domain containing protein 0.014 0.1268 0.1264
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0511 0.0507
Echinococcus granulosus DCC interacting protein 13 beta 0.0017 0.0005 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0216 0.0945
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0105 0.0118
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0208 0.1967 0.8771
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.0233 0.026
Leishmania major mitotic cyclin, putative 0.0018 0.0009 0.004
Toxoplasma gondii protein kinase domain-containing protein 0.0023 0.0061 0.0272
Brugia malayi hypothetical protein 0.0039 0.0233 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0009 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.1691 0.1914
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0321 0.0317
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0017 0.0005 0.00000005655
Echinococcus granulosus cyclin dependent kinase 0.0181 0.1691 0.188
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0157 0.0177
Trichomonas vaginalis centaurin gamma, putative 0.0017 0.0005 0.00000005655
Echinococcus multilocularis cyclin G2 0.0018 0.0009 0.001
Schistosoma mansoni centaurin alpha 0.0017 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0233 0.026
Entamoeba histolytica protein kinase, putative 0.0234 0.2243 1
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0043 0.027 0.03
Schistosoma mansoni cyclin B 0.0073 0.0579 0.0655
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0579 0.2408
Schistosoma mansoni goodpasture antigen-binding protein 0.0017 0.0005 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0157 0.0174
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0483 0.0559
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0145 0.1321 0.1468
Echinococcus multilocularis beta adrenergic receptor kinase 0.0385 0.3795 0.4219
Toxoplasma gondii AtPH1 family protein 0.0017 0.0005 0.0021
Loa Loa (eye worm) cyclin C 0.0018 0.0009 0.0004
Brugia malayi CXXC zinc finger family protein 0.003 0.0138 0.0133
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0511 0.0579
Loa Loa (eye worm) AUR protein kinase 0.0234 0.2243 0.2239
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0849 0.8574 0.9534
Entamoeba histolytica hypothetical protein 0.0039 0.0233 0.1041
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.0009 0.0004
Echinococcus granulosus cytohesin 1 0.0017 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0321 0.0364
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0105 0.0908 0.4036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0154 0.0149
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Brugia malayi PXA domain containing protein 0.0039 0.0233 0.0229
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.2309 0.2814
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0043 0.027 0.03
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0234 0.2243 0.2494
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0228 0.2173 0.9094
Onchocerca volvulus 0.0021 0.0045 0.017
Echinococcus multilocularis Pleckstrin y 0.0017 0.0005 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0234 0.2243 1
Mycobacterium ulcerans hypothetical protein 0.0038 0.0216 0.023
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0033 0.0166 0.0187
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0157 0.0698
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.029 0.0285
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0216 0.0887
Loa Loa (eye worm) cyclin domain-containing protein 0.0018 0.0009 0.0004
Echinococcus granulosus cyclins 0.0073 0.0579 0.0644
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0216 0.0245
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.0233 0.0229
Loa Loa (eye worm) hypothetical protein 0.0036 0.0195 0.0191
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0216 0.0887
Loa Loa (eye worm) cyclin domain-containing protein 0.0073 0.0579 0.0575
Echinococcus granulosus dynamin 1 0.0017 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.001
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0216 0.023
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0018 0.0009 0.001
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0511 0.0579
Entamoeba histolytica hypothetical protein 0.0033 0.0166 0.0738
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus granulosus Pleckstrin y 0.0017 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0181 0.1691 0.1687
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Trypanosoma cruzi hypothetical protein 0.0017 0.0005 0.0021
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.027 0.03
Trypanosoma cruzi cyclin, putative 0.0073 0.0579 0.2581
Loa Loa (eye worm) TK/ABL protein kinase 0.0027 0.0109 0.0104
Echinococcus granulosus cyclin y 0.0018 0.0009 0.001
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0017 0.0005 0.00000005655
Trypanosoma cruzi cyclin, putative 0.0073 0.0579 0.2581
Echinococcus granulosus myotubularin protein 13 0.0017 0.0005 0.0005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0216 0.0245
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0061 0.0272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0157 0.0177
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0027 0.0109 0.0121
Echinococcus multilocularis cpg binding protein 0.0032 0.0155 0.0173
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0181 0.1691 0.1687
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Schistosoma mansoni dynamin 0.0017 0.0005 0.0005
Echinococcus multilocularis myotubularin protein 13 0.0017 0.0005 0.0005
Schistosoma mansoni syntrophin 0.0017 0.0005 0.0005
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0385 0.3795 0.3792
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0233 0.0264
Trichomonas vaginalis cyclin B3, putative 0.0018 0.0009 0.0019
Trypanosoma cruzi acetyl-CoA carboxylase 0.009 0.0752 0.3353
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0234 0.2243 0.2494
Brugia malayi PXA domain containing protein 0.0039 0.0233 0.0229
Echinococcus multilocularis geminin 0.0177 0.1656 0.1841
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0017 0.0005 0.0005
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0216 0.508
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0233 0.026
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0511 0.0579
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0032 0.0154 0.0174
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0208 0.1967 0.8771
Toxoplasma gondii cyclin 4, putative 0.0018 0.0009 0.004
Echinococcus multilocularis NCK adaptor protein 0.0032 0.0154 0.0171
Brugia malayi Cyclin, N-terminal domain containing protein 0.0073 0.0579 0.0575
Brugia malayi Protein kinase domain containing protein 0.0027 0.0109 0.0104
Echinococcus granulosus tyrosine protein kinase Src64B 0.0043 0.027 0.03
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0023 0.0061 0.0272
Loa Loa (eye worm) RGS-3 protein 0.0039 0.0233 0.0229
Echinococcus multilocularis cyclin y 0.0018 0.0009 0.001
Echinococcus multilocularis cyclin B 0.0073 0.0579 0.0644
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0023 0.0061 0.0272
Echinococcus granulosus Rho GTPase activating protein 24 0.0017 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0321 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0233 0.096
Mycobacterium tuberculosis Conserved protein 0.0038 0.0216 0.023
Echinococcus multilocularis G1:S specific cyclin D1 0.0018 0.0009 0.001
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.0233 0.0264
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0061 0.0069
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0212
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0874 0.8833 1
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0018 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.1691 0.707
Trypanosoma brucei unspecified product 0.0036 0.0202 0.0899
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.0009 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0017 0.0005 0.0005
Trichomonas vaginalis cyclins, putative 0.0073 0.0579 0.2408
Onchocerca volvulus 0.0027 0.0109 0.0436
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0233 0.0264
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0017 0.0005 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0216 0.023
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0208 0.1967 0.8771
Schistosoma mansoni tyrosine kinase 0.0027 0.0109 0.0123
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0228 0.2173 0.9094
Trichomonas vaginalis cyclin A, putative 0.0018 0.0009 0.0019
Entamoeba histolytica protein kinase, putative 0.0021 0.0049 0.0219
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.027 0.03
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Brugia malayi Cyclin, N-terminal domain containing protein 0.0073 0.0579 0.0575
Loa Loa (eye worm) AGC/AKT protein kinase 0.0023 0.0061 0.0056
Echinococcus granulosus Oxysterol binding protein 11 0.0017 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Toxoplasma gondii aurora kinase 0.0234 0.2243 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.0216 0.023
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0511 0.0507
Loa Loa (eye worm) hypothetical protein 0.0052 0.0366 0.0361
Schistosoma mansoni g1/s-specific cyclin C 0.0018 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Loa Loa (eye worm) hypothetical protein 0.0039 0.0233 0.0229
Entamoeba histolytica protein kinase, putative 0.0234 0.2243 1
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Loa Loa (eye worm) hypothetical protein 0.0027 0.0109 0.0104
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Trichomonas vaginalis esterase, putative 0.0038 0.0216 0.0887
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0483 0.2152
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.1367 0.5712
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0233 0.026
Entamoeba histolytica hypothetical protein 0.0017 0.0005 0.0021
Schistosoma mansoni nck2/grb4 0.0032 0.0154 0.0174
Echinococcus multilocularis cyclin dependent kinase 0.0181 0.1691 0.188
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0055 0.0396 0.0452
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0212
Echinococcus multilocularis cyclin dependent kinase 1 0.0181 0.1691 0.188
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0055 0.0396 0.0441
Echinococcus granulosus Pleckstrin y 0.0017 0.0005 0.0005
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0017 0.0005 0.0021
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0018 0.0009 0.004
Giardia lamblia Kinase, CMGC CDK 0.0181 0.1691 0.7528
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0043 0.027 0.03
Brugia malayi TAR-binding protein 0.0066 0.0511 0.0507
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0181 0.1691 0.7538
Plasmodium falciparum oxysterol-binding protein, putative 0.0017 0.0005 0.0021
Brugia malayi RNA binding protein 0.0066 0.0511 0.0507
Trichomonas vaginalis glucosylceramidase, putative 0.0228 0.2173 0.9094
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0018 0.0009 0.004
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0234 0.2243 1
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0023 0.0061 0.0272
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Brugia malayi Variant SH3 domain containing protein 0.0032 0.0154 0.0149
Loa Loa (eye worm) cyclin domain-containing protein 0.0018 0.0009 0.0004
Plasmodium falciparum cyclin 0.0073 0.0579 0.2581
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0073 0.0579 0.0644
Brugia malayi beta-lactamase 0.0038 0.0216 0.0212
Entamoeba histolytica protein kinase, putative 0.0023 0.0061 0.0272
Trypanosoma brucei rac serine-threonine kinase, putative 0.0023 0.0061 0.0272
Schistosoma mansoni cpg binding protein 0.0032 0.0155 0.0176
Trichomonas vaginalis glucosylceramidase, putative 0.0228 0.2173 0.9094
Trypanosoma cruzi cdc2-related kinase 3 0.0181 0.1691 0.7538
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0511 0.0579
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0233 0.0229
Echinococcus multilocularis cyclins 0.0073 0.0579 0.0644
Toxoplasma gondii hypothetical protein 0.0018 0.0009 0.004
Entamoeba histolytica hypothetical protein 0.0017 0.0005 0.0021
Entamoeba histolytica ARF GTPase activating protein, putative 0.0017 0.0005 0.0021
Brugia malayi SH2 domain containing protein 0.0027 0.0109 0.0104
Leishmania major hypothetical protein, conserved 0.0038 0.0216 0.0964
Trichomonas vaginalis cyclins, putative 0.0018 0.0009 0.0019
Trypanosoma cruzi mitotic cyclin, putative 0.0018 0.0009 0.004
Leishmania major propionyl-coa carboxylase beta chain, putative 0.002 0.003 0.0134
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0181 0.1691 0.1687
Trypanosoma cruzi cdc2-related kinase 1 0.0181 0.1691 0.7538
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.0009 0.0004
Entamoeba histolytica PH domain containing protein 0.0017 0.0005 0.0021
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0023 0.0061 0.0272
Brugia malayi protein-tyrosine kinase 0.0027 0.0109 0.0104
Echinococcus multilocularis oxysterol binding protein 3 0.0017 0.0005 0.0005
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0017 0.0005 0.0021
Trichomonas vaginalis cyclin D, putative 0.0073 0.0579 0.2408
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0027 0.0109 0.0121
Schistosoma mansoni myotubularin-related protein 0.0017 0.0005 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0216 0.0964
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.027 0.03
Echinococcus multilocularis growth factor receptor bound protein 2 0.0032 0.0154 0.0171
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Brugia malayi SRC-1 0.0043 0.027 0.0265
Trichomonas vaginalis cyclin B, putative 0.0073 0.0579 0.2408
Echinococcus multilocularis Pleckstrin y 0.0017 0.0005 0.0005
Brugia malayi hypothetical protein 0.0128 0.1149 0.1145
Entamoeba histolytica cyclin family protein 0.0073 0.0579 0.2581
Schistosoma mansoni dynamin 0.0017 0.0005 0.0005
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0023 0.0061 0.0252
Echinococcus granulosus tar DNA binding protein 0.0066 0.0511 0.0568
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.014 0.1268 0.1264
Echinococcus granulosus mitogen activated protein kinase 11 0.0208 0.1967 0.2187
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0216 0.023
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Leishmania major protein kinase, putative 0.0023 0.0061 0.0272
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0346 0.3389 0.3768
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0033 0.0166 0.0184
Echinococcus granulosus serine/threonine protein kinase 0.0023 0.0061 0.0068
Brugia malayi Variant SH3 domain containing protein 0.0032 0.0154 0.0149
Schistosoma mansoni hypothetical protein 0.0428 0.424 0.48
Echinococcus granulosus c src tyrosine kinase 0.0043 0.027 0.03
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0234 0.2243 1
Plasmodium falciparum protein kinase 5 0.0181 0.1691 0.7538
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0025 0.0082 0.0367
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0511 0.0507
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0234 0.2243 1
Schistosoma mansoni cpg binding protein 0.0032 0.0155 0.0176
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.2079 0.2076
Trichomonas vaginalis cyclin B, putative 0.0073 0.0579 0.2408
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0181 0.1691 0.7538
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.027 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.1691 0.1914
Echinococcus multilocularis GRB2 associated binding protein 3 0.0017 0.0005 0.0005
Entamoeba histolytica protein kinase , putative 0.0234 0.2243 1
Echinococcus granulosus oxysterol binding protein 9 0.0017 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0483 0.0537
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.1691 0.707
Echinococcus multilocularis cyclin G2 0.0018 0.0009 0.001
Echinococcus granulosus beta-adrenergic receptor kinase 0.0385 0.3795 0.4219
Trypanosoma cruzi cdc2-related kinase 1 0.0181 0.1691 0.7538
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0018 0.0009 0.004
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0055 0.0396 0.0452
Loa Loa (eye worm) hypothetical protein 0.0039 0.0233 0.0229
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0017 0.0005 0.000000013493
Echinococcus multilocularis cyclin 0.0018 0.0009 0.001
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.0233 0.0229
Leishmania major carboxylase, putative 0.0055 0.0396 0.1767
Echinococcus granulosus mitogen activated protein kinase 14 0.0208 0.1967 0.2187
Brugia malayi cell division control protein 2 homolog 0.0181 0.1691 0.1687
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0018 0.0009 0.001
Plasmodium falciparum PH domain-containing protein, putative 0.0017 0.0005 0.0021
Leishmania major protein kinase, putative 0.0023 0.0061 0.0272
Onchocerca volvulus Huntingtin homolog 0.0128 0.1149 0.4799
Loa Loa (eye worm) cyclin domain-containing protein 0.0018 0.0009 0.0004
Brugia malayi beta-lactamase family protein 0.0038 0.0216 0.0212
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0027 0.0109 0.0121
Entamoeba histolytica hypothetical protein 0.0017 0.0005 0.0021
Echinococcus multilocularis cyclin b3 0.0073 0.0579 0.0644
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0157 0.0174
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0017 0.0005 0.0021
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0055 0.0396 0.0452
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0511 0.0568
Echinococcus granulosus G protein coupled receptor kinase 1 0.0346 0.3389 0.3768
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0233 0.026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0004
Echinococcus multilocularis actin binding protein anillin 0.0017 0.0005 0.0005
Trichomonas vaginalis cyclin B3, putative 0.0073 0.0579 0.2408
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0018 0.0009 0.004
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0023 0.0061 0.0236
Trichomonas vaginalis cyclins, putative 0.0073 0.0579 0.2408
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0017 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0181 0.1691 0.1687
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0017 0.0005 0.0005
Plasmodium vivax protein kinase Crk2 0.0181 0.1691 0.7533
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0233 0.026
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0181 0.1691 0.7538
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0483 0.0559
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0061 0.0272
Trichomonas vaginalis cyclin B3, putative 0.0018 0.0009 0.0019
Schistosoma mansoni cpg binding protein 0.003 0.0138 0.0156
Echinococcus multilocularis tyrosine protein kinase shark 0.0027 0.0109 0.0121
Trypanosoma brucei cdc2-related kinase 1 0.0181 0.1691 0.7538
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0109 0.0104
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0228 0.2173 0.217
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0233 0.026
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0023 0.0061 0.0272
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0023 0.0061 0.0272
Plasmodium falciparum serine/threonine protein kinase, putative 0.0234 0.2243 1
Echinococcus granulosus cyclin G2 0.0018 0.0009 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0366 0.0361
Echinococcus granulosus pdz domain containing protein 0.0017 0.0005 0.0005
Mycobacterium ulcerans pyruvate carboxylase 0.0055 0.0396 0.0452
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0023 0.0061 0.0272
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0017 0.0005 0.0021
Schistosoma mansoni cyclin k 0.0018 0.0009 0.001
Entamoeba histolytica cyclin family protein 0.0073 0.0579 0.2581
Entamoeba histolytica hypothetical protein 0.0018 0.0009 0.004
Plasmodium falciparum calcium-dependent protein kinase 7 0.0023 0.0061 0.0272
Loa Loa (eye worm) hypothetical protein 0.0073 0.0579 0.0575
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0017 0.0005 0.00000005655
Brugia malayi Pre-SET motif family protein 0.0219 0.2079 0.2076
Echinococcus multilocularis tyrosine protein kinase Abl 0.0043 0.027 0.03
Entamoeba histolytica cell division protein kinase 2, putative 0.0181 0.1691 0.7538
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0105 0.0908 0.4049
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0233 0.026
Toxoplasma gondii pyruvate carboxylase 0.0055 0.0396 0.1767
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0212
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.424 0.4714
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236
Trichomonas vaginalis glucosylceramidase, putative 0.0228 0.2173 0.9094
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0061 0.0236

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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