Detailed information for compound 1798157

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 336.277 | Formula: C14H19Cl2NO2S
  • H donors: 1 H acceptors: 2 LogP: 2.92 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1Cl)C(C1CCNCC1)CS(=O)(=O)C
  • InChi: 1S/C14H19Cl2NO2S/c1-20(18,19)9-12(10-4-6-17-7-5-10)11-2-3-13(15)14(16)8-11/h2-3,8,10,12,17H,4-7,9H2,1H3
  • InChiKey: UFLOUMKALGULCP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0039 0.0095 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0081 0.0369
Plasmodium falciparum thioredoxin reductase 0.0027 0.0042 0.1495
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0077 0.0077
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0226 0.0223
Schistosoma mansoni thyroid hormone receptor 0.0123 0.0468 0.0468
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2246 0.983 0.983
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.0149
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0052 0.0154 0.0251
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0066 0.0102
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0066 0.0063
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0195 0.0787 1
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0039 0.0095 0.0433
Echinococcus granulosus pyruvate kinase 0.0032 0.0066 0.0063
Onchocerca volvulus 0.2285 1 1
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0039 0.0095 0.0095
Onchocerca volvulus 0.005 0.0143 0.014
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0074
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0006 0.0003
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0095 0.0395
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0095
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0077 0.0077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Leishmania major glycerolphosphate mutase, putative 0.0039 0.0095 0.0095
Brugia malayi mbt repeat family protein 0.0043 0.0115 0.0627
Giardia lamblia NADH oxidase lateral transfer candidate 0.0027 0.0042 0.0061
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0066 0.0063
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0006 0.0003
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0077 0.0793
Leishmania major hypothetical protein, conserved 0.0039 0.0095 0.0095
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0107 0.0493
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0049 0.0141 0.0138
Plasmodium falciparum phosphoglycerate mutase, putative 0.0039 0.0095 0.3496
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0039 0.0095 0.0095
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0039 0.0095 0.0433
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0027 0.0042 0.0039
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0077 0.0074
Schistosoma mansoni hypothetical protein 0.0405 0.1713 0.1713
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Schistosoma mansoni pyruvate kinase 0.0032 0.0066 0.0066
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0066 0.0063
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0066 0.0066
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0027 0.0042 0.0061
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.2246 0.983 0.983
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0107 0.0171
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0039 0.0095 0.0091
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0039 0.0095 0.0985
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0039 0.0095 0.0095
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0027 0.0042 0.0042
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0066 0.0066
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0081 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0095 0.0091
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0102 0.0099
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0077 0.0121
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Toxoplasma gondii phosphoglycerate mutase family protein 0.0039 0.0095 0.2352
Schistosoma mansoni bromodomain containing protein 0.0072 0.0244 0.0244
Echinococcus granulosus zinc finger protein 0.0024 0.0028 0.0025
Brugia malayi Bromodomain containing protein 0.0086 0.0302 0.1675
Leishmania major pyruvate kinase 0.0032 0.0066 0.0066
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0066 0.0293
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0176 0.07 0.7754
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0052 0.0154 0.0251
Trypanosoma brucei unspecified product 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0292 0.1212 0.1209
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0195 0.0787 0.8721
Onchocerca volvulus Protein UBASH3A homolog 0.0039 0.0095 0.0091
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0006
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0143 0.0143
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0081 0.0439
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.0039 0.0095 0.015
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0081 0.0081
Schistosoma mansoni 6-phosphofructokinase 0.2285 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.008 0.0278 0.0275
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0176 0.07 0.7754
Echinococcus multilocularis thioredoxin glutathione reductase 0.0078 0.0267 0.0263
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0077 0.0348
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0107 0.0104
Loa Loa (eye worm) hypothetical protein 0.0163 0.0643 0.064
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0028 0.005 0.005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0102 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0095 0.0433
Brugia malayi phosphoglycerate mutase family protein 0.0039 0.0095 0.0512
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0043 0.0115 0.0115
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0052 0.0154 0.1646
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.4535
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0026 0.0023
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0081 0.0128
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0039 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0111 0.0416 0.0413
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0027 0.0042 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0081 0.0369
Loa Loa (eye worm) norepinephrine transporter 0.0292 0.1212 0.1209
Brugia malayi Thioredoxin reductase 0.0077 0.0264 0.1465
Echinococcus multilocularis phosphoglycerate mutase 0.0039 0.0095 0.0091
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0081 0.0081
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0052 0.0154 0.015
Echinococcus multilocularis zinc finger protein 0.0024 0.0028 0.0025
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Leishmania major DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Echinococcus granulosus serotonin transporter 0.0292 0.1212 0.1209
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0107 0.2903
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0055 0.0167 0.0164
Brugia malayi Inositol-1 0.0041 0.0107 0.0581
Plasmodium vivax thioredoxin reductase, putative 0.0077 0.0264 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0194 0.682
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0039 0.0095 0.0395
Loa Loa (eye worm) hypothetical protein 0.0043 0.0115 0.0112
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Entamoeba histolytica hypothetical protein 0.004 0.0102 0.0163
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1348 0.5871 1
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0143 0.0143
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0066 0.0066
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0077 0.0348
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0039 0.0095 0.0433
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0975 0.4224 0.4224
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0081 0.0081
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.014
Echinococcus multilocularis polycomb protein SCMH1 0.0043 0.0115 0.0112
Schistosoma mansoni lipoxygenase 0.0107 0.0396 0.0396
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0422 0.1786 0.1783
Echinococcus multilocularis serotonin transporter 0.0292 0.1212 0.1209
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0201 0.0201
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0027 0.0042 0.1495
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.4535
Schistosoma mansoni aldehyde dehydrogenase 0.0055 0.0167 0.0167
Brugia malayi hypothetical protein 0.005 0.0143 0.0784
Loa Loa (eye worm) hypothetical protein 0.0039 0.0095 0.0091
Trichomonas vaginalis mercuric reductase, putative 0.0027 0.0042 0.0176
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0152 0.0149
Mycobacterium tuberculosis Conserved protein 0.0035 0.0077 0.0793
Entamoeba histolytica pyruvate kinase, putative 0.0022 0.0023 0.0029
Mycobacterium ulcerans hypothetical protein 0.1348 0.5871 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0107 0.0171
Echinococcus granulosus phosphoglycerate mutase 0.0039 0.0095 0.0091
Onchocerca volvulus 0.005 0.0143 0.014
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0088 0.03
Mycobacterium ulcerans acid phosphatase 0.0039 0.0095 0.015
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0095
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0081 0.0128
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0107 0.0396 0.0393
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0039 0.0095 0.0095
Trypanosoma brucei glycerolphosphate mutase, putative 0.0039 0.0095 0.0095
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.0416 0.2314
Onchocerca volvulus 0.0061 0.0194 0.0191
Schistosoma mansoni aldehyde dehydrogenase 0.0055 0.0167 0.0167
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0039 0.0095 0.0091
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0107 0.0493
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0066 0.0353
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.005 0.0047
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0039 0.0095 0.015
Schistosoma mansoni inositol monophosphatase 0.0041 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0039 0.0095 0.0091
Schistosoma mansoni phosphoglycerate mutase 0.0039 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0063
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0039 0.0095 0.0095
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0143 0.014
Trichomonas vaginalis glutathione reductase, putative 0.0027 0.0042 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0039 0.0095 0.0985
Schistosoma mansoni inositol monophosphatase 0.0041 0.0107 0.0107
Schistosoma mansoni hypothetical protein 0.0111 0.0416 0.0416
Mycobacterium ulcerans beta-lactamase 0.0035 0.0077 0.0121
Mycobacterium tuberculosis Probable oxidoreductase 0.0195 0.0787 0.8721
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0107 0.0107
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0039 0.0095 0.5186
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0292 0.1212 0.1212
Plasmodium vivax amine transporter, putative 0.005 0.0143 0.5352
Schistosoma mansoni loxhd1 0.0018 0.0003 0.0003
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0039 0.0095 0.0095
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0077 0.0264 0.2885
Echinococcus granulosus endonuclease exonuclease phosphatase 0.017 0.0675 0.0672
Echinococcus granulosus dnaJ subfamily B 0.0405 0.1713 0.171
Brugia malayi Pre-SET motif family protein 0.0061 0.0194 0.1069
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0077 0.0074
Plasmodium falciparum pyruvate kinase 0.0032 0.0066 0.2406
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0081 0.0078
Plasmodium vivax glutathione reductase, putative 0.0077 0.0264 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0081 0.0081
Brugia malayi phosphoglycerate mutase family protein 0.0039 0.0095 0.0512
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0081 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Echinococcus granulosus histone acetyltransferase MYST2 0.0049 0.0141 0.0138
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0066 0.0353
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0027 0.0042 0.0042
Echinococcus granulosus dna polymerase kappa 0.0019 0.0006 0.0003
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0039 0.0095 0.0985
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0009 0.0005
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0107 0.0104
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0095 0.0985
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0095
Giardia lamblia Pyruvate kinase 0.0032 0.0066 0.0102
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.005 0.0143 0.0784
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0143 0.0143
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2246 0.983 0.983
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0088 0.0909
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0194 0.0191
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0066 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0055 0.0167 0.0274
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0102 0.0099
Mycobacterium leprae probable isochorismate synthase EntC 0.0039 0.0095 0.0395
Loa Loa (eye worm) pyruvate kinase-PB 0.0022 0.0023 0.002
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.014
Leishmania major hypothetical protein, conserved 0.0039 0.0095 0.0095
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0003
Schistosoma mansoni hypothetical protein 0.0023 0.0026 0.0026
Schistosoma mansoni sodium/chloride dependent transporter 0.0292 0.1212 0.1212
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0039 0.0095 0.0433
Schistosoma mansoni hypothetical protein 0.004 0.0102 0.0102
Brugia malayi beta-lactamase family protein 0.0035 0.0077 0.0416
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0018
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0039 0.0095 0.0985
Toxoplasma gondii hypothetical protein 0.005 0.0143 0.4535
Treponema pallidum sodium- and chloride- dependent transporter 0.0292 0.1212 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0042 0.0042
Echinococcus granulosus phosphoglycerate mutase 0.0039 0.0095 0.0091
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0077 0.0348
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1348 0.5871 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0009 0.0009
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0055 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0039 0.0095 0.0091
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0081 0.0078
Mycobacterium ulcerans hypothetical protein 0.0035 0.0077 0.0121
Entamoeba histolytica hypothetical protein 0.004 0.0102 0.0163
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.002 0.0011 0.0044
Schistosoma mansoni sex comb on midleg homolog 0.0043 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.2285 1 1
Leishmania major phosphoglycerate mutase protein, putative 0.0039 0.0095 0.0095
Echinococcus multilocularis phosphoglycerate mutase 0.0039 0.0095 0.0091
Toxoplasma gondii phosphoglycerate mutase family protein 0.0039 0.0095 0.2352
Loa Loa (eye worm) mbt repeat family protein 0.0043 0.0115 0.0112
Schistosoma mansoni zinc finger protein 0.0024 0.0028 0.0028
Mycobacterium leprae Probable lipase LipE 0.0035 0.0077 0.0156
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0039 0.0095 0.0095
Leishmania major DNA polymerase eta, putative 0.0019 0.0006 0.0006
Toxoplasma gondii aldehyde dehydrogenase 0.0055 0.0167 0.5614
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0143 0.0143
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0975 0.4224 0.4224
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0143 0.0143
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0009 0.0009
Brugia malayi Calcitonin receptor-like protein seb-1 0.0163 0.0643 0.359
Trypanosoma brucei phosphoglycerate mutase, putative 0.0039 0.0095 0.0095
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0052 0.0154 0.015
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0006 0.0003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0074
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2285 1 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0052 0.0154 0.0154
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0975 0.4224 0.4224
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0027 0.0042 0.0061
Brugia malayi beta-lactamase 0.0035 0.0077 0.0416
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0055 0.0167 0.0164
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0042 0.0042
Chlamydia trachomatis pyruvate kinase 0.0032 0.0066 0.2361
Onchocerca volvulus Protein UBASH3A homolog 0.0039 0.0095 0.0091
Onchocerca volvulus 0.0035 0.0077 0.0074
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0039 0.0095 0.0433
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0074
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0042 0.0042
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0152 0.0149
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0066 0.2406
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.2285 1 1
Brugia malayi hypothetical protein 0.004 0.0102 0.0554
Schistosoma mansoni sex comb on midleg homolog 0.0043 0.0115 0.0115
Toxoplasma gondii hypothetical protein 0.005 0.0143 0.4535
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0039 0.0095 0.0095
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0066 0.0063
Brugia malayi CXXC zinc finger family protein 0.0028 0.005 0.0262
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0039 0.0095 0.0395
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0077 0.0121
Plasmodium falciparum amino acid transporter, putative 0.005 0.0143 0.5352
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0138
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.0039 0.0095 0.015
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0066 0.0066
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0107 0.0107
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0143 0.014
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0039 0.0095 0.2352
Onchocerca volvulus 0.0035 0.0077 0.0074
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0077 0.0793
Schistosoma mansoni phosphoglycerate mutase 0.0039 0.0095 0.0095
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0102 0.0102
Leishmania major phosphoglycerate mutase family member 5, putative 0.0039 0.0095 0.0095
Schistosoma mansoni polycystin 1-related 0.0018 0.0003 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0077 0.0077
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2285 1 1
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0039 0.0095 0.0095
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0143 0.014
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0039 0.0095 0.0091
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.005 0.0143 0.014
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0163 0.0643 0.359
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.005 0.0143 1
Echinococcus multilocularis dna polymerase eta 0.0019 0.0006 0.0003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0226 0.0223
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0039 0.0095 0.015
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0143 0.0143
Schistosoma mansoni thyroid hormone receptor 0.0123 0.0468 0.0468
Echinococcus multilocularis pyruvate kinase 0.0032 0.0066 0.0063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0278 0.0278
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0049 0.0141 0.0775
Schistosoma mansoni myelin transcription factor 1 myt1 0.0049 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0039 0.0095 0.015
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0066 0.0293
Plasmodium vivax phosphoglucomutase-2, putative 0.0039 0.0095 0.3496
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0077 0.0416
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0077 0.0793
Loa Loa (eye worm) hypothetical protein 0.0043 0.0114 0.0111
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0194 0.0194
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0066 0.1071
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0107 1
Giardia lamblia Hypothetical protein 0.1348 0.5871 1
Mycobacterium leprae Possible phosphoglycerate mutase 0.0039 0.0095 0.0395
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0074
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0006 0.0006
Plasmodium falciparum thioredoxin reductase 0.0077 0.0264 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0077 0.0077
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0077 0.0793
Onchocerca volvulus 0.0043 0.0115 0.0112
Toxoplasma gondii phosphoglycerate mutase family protein 0.0039 0.0095 0.2352
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0143 0.0143
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0152 0.0149
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.005 0.0143 0.014
Onchocerca volvulus 0.0039 0.0095 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0055 0.0167 0.0274
Mycobacterium ulcerans phosphoglycerate mutase 0.0039 0.0095 0.015
Loa Loa (eye worm) hypothetical protein 0.2246 0.983 0.983
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0039 0.0095 0.0095
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0027 0.0042 0.0042
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0006 0.0003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0107 0.0493
Loa Loa (eye worm) hypothetical protein 0.131 0.5701 0.5699
Leishmania major pyruvate kinase 0.0032 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0095
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0077 0.0793
Mycobacterium ulcerans hypothetical protein 0.0039 0.0095 0.015
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0152 0.0834
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0027 0.0042 0.1495
Giardia lamblia Hypothetical protein 0.1348 0.5871 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0143 0.0143
Mycobacterium ulcerans phosphoglycerate mutase 0.0039 0.0095 0.015
Plasmodium falciparum glutathione reductase 0.0077 0.0264 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0006
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.005 0.0143 0.014
Plasmodium falciparum glutathione reductase 0.0027 0.0042 0.1495
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0081 0.0081
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0012 0.0008
Brugia malayi glutathione reductase 0.0077 0.0264 0.1465
Onchocerca volvulus 0.0035 0.0077 0.0074
Onchocerca volvulus 0.0028 0.005 0.0047
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0102 0.0099
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0027 0.0042 0.0042
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.0784
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0095 0.0395
Mycobacterium tuberculosis Probable reductase 0.0176 0.07 0.7754
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0095 0.0433
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.008 0.0278 0.0275
Schistosoma mansoni rab6-interacting 0.0018 0.0003 0.0003
Onchocerca volvulus Protein UBASH3A homolog 0.0039 0.0095 0.0091
Echinococcus granulosus phosphoglycerate mutase 0.0039 0.0095 0.0091
Leishmania major trypanothione reductase 0.0077 0.0264 0.0264
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.005 0.0143 0.014
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0081 0.0078
Leishmania major hypothetical protein, unknown function 0.0039 0.0095 0.0095
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0181 0.0178
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0043 0.004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0221 0.0901 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0043 0.0115 0.0112
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0194 0.0194
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0292 0.1212 0.6781
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.1713 0.171
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0042 0.0042
Echinococcus granulosus GPCR family 2 0.0052 0.0152 0.0149
Plasmodium vivax SET domain protein, putative 0.0061 0.0194 0.7296
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0039 0.0095 0.0095
Toxoplasma gondii ABC1 family protein 0.0035 0.0077 0.1577
Entamoeba histolytica hypothetical protein 0.004 0.0102 0.0163
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0048 0.0138 0.0135
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0006 0.0006
Toxoplasma gondii phosphoglycerate mutase 0.0039 0.0095 0.2352
Onchocerca volvulus 0.0039 0.0095 0.0091
Loa Loa (eye worm) thioredoxin reductase 0.0077 0.0264 0.0261
Leishmania major hypothetical protein, conserved 0.0035 0.0077 0.0077
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0039 0.0095 0.0095
Mycobacterium tuberculosis Conserved protein 0.0035 0.0077 0.0793
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0077 0.0793
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0006 0.0006
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2285 1 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.017 0.0675 0.0672
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0052 0.0154 0.0154
Mycobacterium ulcerans lipase LipD 0.0035 0.0077 0.0121
Onchocerca volvulus 0.005 0.0143 0.014
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0039 0.0095 0.0985
Trichomonas vaginalis esterase, putative 0.0035 0.0077 0.0348
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0152 0.0149
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0077 0.0156
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0077 0.0348
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0066 0.0667
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0043 0.004
Schistosoma mansoni lipoxygenase 0.0075 0.0254 0.0254
Echinococcus multilocularis SAM and MBT domain containing protein 0.0043 0.0115 0.0112
Mycobacterium ulcerans phosphoglyceromutase 0.0039 0.0095 0.015
Leishmania major phosphoglycerate mutase, putative 0.0039 0.0095 0.0095
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0114 0.0427 0.0424
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0081 0.0081
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0006 0.0006
Loa Loa (eye worm) solute carrier family 6 member 4 0.0292 0.1212 0.1209
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0077 0.0077
Onchocerca volvulus Protein UBASH3A homolog 0.0039 0.0095 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0035 0.0077 0.0793
Brugia malayi PHD-finger family protein 0.003 0.0055 0.0288
Echinococcus granulosus dna polymerase eta 0.0019 0.0006 0.0003
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0143 0.014
Mycobacterium ulcerans hypothetical protein 0.0039 0.0095 0.015
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0018
Echinococcus multilocularis phosphoglycerate mutase 0.0039 0.0095 0.0091
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0081 0.0078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0055 0.0167 0.1796
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0066 0.0063
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0074
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0095
Toxoplasma gondii thioredoxin reductase 0.0077 0.0264 1
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0095 0.0395
Loa Loa (eye worm) beta-lactamase 0.0035 0.0077 0.0074
Schistosoma mansoni sodium-dependent amino acid transporter 0.005 0.0143 0.0143
Mycobacterium ulcerans lipoprotein LpqD 0.0039 0.0095 0.015
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0027 0.0042 0.0219
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Onchocerca volvulus 0.048 0.2043 0.204
Mycobacterium ulcerans hydrolase MutT1 0.0039 0.0095 0.015
Trypanosoma cruzi trypanothione reductase, putative 0.0077 0.0264 0.0264
Plasmodium vivax phosphoglycerate mutase, putative 0.0039 0.0095 0.3496
Toxoplasma gondii phosphoglycerate mutase family protein 0.0039 0.0095 0.2352
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.008 0.0278 0.0275
Mycobacterium ulcerans aldehyde dehydrogenase 0.0055 0.0167 0.0274
Loa Loa (eye worm) inositol-1 0.0041 0.0107 0.0104
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0152 0.0834
Entamoeba histolytica hypothetical protein 0.004 0.0102 0.0163
Brugia malayi mbt repeat family protein 0.0043 0.0115 0.0627
Loa Loa (eye worm) serotonin transporter b 0.0292 0.1212 0.1209
Loa Loa (eye worm) hypothetical protein 0.0292 0.1212 0.1209
Echinococcus granulosus polycomb protein SCMH1 0.0043 0.0115 0.0112
Echinococcus multilocularis cpg binding protein 0.0032 0.0067 0.0063
Echinococcus multilocularis pyruvate kinase 0.0032 0.0066 0.0063
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2246 0.983 0.983
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0039 0.0095 0.0095
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0114 0.0427 0.0424
Loa Loa (eye worm) phosphoglycerate mutase 0.0039 0.0095 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Schistosoma mansoni DNA polymerase eta 0.0019 0.0006 0.0006
Loa Loa (eye worm) glutathione reductase 0.0077 0.0264 0.0261
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0184 0.6371
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0027 0.0042 0.1495
Plasmodium vivax hypothetical protein, conserved 0.005 0.0143 0.5352
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0107 0.0396 0.0393
Brugia malayi beta-lactamase family protein 0.0035 0.0077 0.0416
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0077 0.0074
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0107 0.0107
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0027 0.0042 0.0061
Schistosoma mansoni hypothetical protein 0.0114 0.0427 0.0427
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0039 0.0095 0.0095
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0039 0.0095 0.0095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0049 0.0142 0.0139
Echinococcus multilocularis phosphoglycerate mutase 0.0039 0.0095 0.0091
Brugia malayi Bromodomain containing protein 0.0043 0.0114 0.0619
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0027 0.0042 0.0039
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.0784
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.0784
Echinococcus granulosus cpg binding protein 0.0032 0.0067 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0081 0.0369
Echinococcus granulosus pyruvate kinase 0.0032 0.0066 0.0063
Brugia malayi Pre-SET motif family protein 0.0422 0.1786 1
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.005 0.0143 0.014
Loa Loa (eye worm) hypothetical protein 0.0292 0.1212 0.1209
Loa Loa (eye worm) hypothetical protein 0.0046 0.0126 0.0122
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0039 0.0095 0.0091
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0143 0.014
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.002
Plasmodium falciparum transporter, putative 0.005 0.0143 0.5352
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0152
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0176 0.07 0.7754
Mycobacterium tuberculosis Probable dehydrogenase 0.0176 0.07 0.7754
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0027 0.0042 0.1495
Echinococcus multilocularis thyroid hormone receptor alpha 0.0123 0.0468 0.0465
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0043 0.0043
Schistosoma mansoni rab6-interacting 0.0018 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0003
Trichomonas vaginalis set domain proteins, putative 0.048 0.2043 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0043 0.0115 0.0112
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.002 0.0011 0.0044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0176 0.07 0.7754
Onchocerca volvulus 0.0039 0.0095 0.0091
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0154 0.0844
Schistosoma mansoni cpg binding protein 0.0032 0.0067 0.0067
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0077 0.2836
Echinococcus multilocularis GPCR, family 2 0.0052 0.0152 0.0149
Brugia malayi UBASH3A protein homolog 0.0039 0.0095 0.0512
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0077 0.0348
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0143 0.014
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0095
Echinococcus multilocularis pyruvate kinase 0.0025 0.0036 0.0033
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.0975 0.4224 0.4224
Echinococcus multilocularis phosphoglycerate mutase 0.0039 0.0095 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Loa Loa (eye worm) MBCTL1 0.0049 0.0141 0.0138
Echinococcus granulosus phosphoglycerate mutase 0.0039 0.0095 0.0091
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0049 0.0141 0.0138
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0152
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0107 0.0107
Echinococcus granulosus thioredoxin glutathione reductase 0.0078 0.0267 0.0263
Trypanosoma brucei trypanothione reductase 0.0077 0.0264 0.0264
Mycobacterium tuberculosis Conserved protein 0.0039 0.0095 0.0985
Loa Loa (eye worm) hypothetical protein 0.0079 0.0274 0.027
Echinococcus multilocularis histone acetyltransferase MYST2 0.0049 0.0141 0.0138
Schistosoma mansoni hypothetical protein 0.0263 0.1083 0.1083
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0143 0.4535
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0278 0.0278
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0039 0.0095 0.0985
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.014
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0152 0.0149
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0195 0.0787 0.8721
Echinococcus multilocularis phosphoglycerate mutase 0.0039 0.0095 0.0091
Treponema pallidum phosphoglyceromutase 0.0039 0.0095 0.0447
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0074
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2285 1 1
Plasmodium falciparum phosphoglucomutase-2 0.0039 0.0095 0.3496
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0077 0.0793
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0078
Schistosoma mansoni pyruvate kinase 0.0032 0.0066 0.0066
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0176 0.07 0.8799
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0039 0.0095 0.0395
Echinococcus granulosus phosphoglycerate mutase 0.0039 0.0095 0.0091
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0292 0.1212 0.1209
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0163 0.0643 0.064
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0042 0.0042
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0039 0.0095 0.0985
Schistosoma mansoni cpg binding protein 0.0032 0.0067 0.0067
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0027 0.0042 0.0042

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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