Detailed information for compound 180454

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 207.183 | Formula: C10H9NO4
  • H donors: 2 H acceptors: 4 LogP: -0.18 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1C=C2CC(N=C2C=C1O)(C)C(=O)O
  • InChi: 1S/C10H9NO4/c1-10(9(14)15)4-5-2-7(12)8(13)3-6(5)11-10/h2-3,13H,4H2,1H3,(H,14,15)
  • InChiKey: FCLUIOWZXOVXDW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0026 0.0036 0.5
Onchocerca volvulus Huntingtin homolog 0.0076 0.0268 0.1239
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0183 0.0766 0.3454
Plasmodium vivax SET domain protein, putative 0.006 0.0191 1
Toxoplasma gondii hypothetical protein 0.0026 0.0036 0.1568
Brugia malayi beta-lactamase family protein 0.0042 0.0108 0.0486
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0191 0.1216
Schistosoma mansoni tubulin subunit alpha 0.0048 0.0136 0.0863
Brugia malayi nuclear hormone receptor 0.0086 0.0316 0.1424
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0183 0.0766 0.3454
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0028 0.0046 0.0292
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0208 0.0879 0.0879
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0038 0.0092 0.0128
Schistosoma mansoni lipoxygenase 0.0162 0.0669 0.4258
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0036 0.0229
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.0162
Giardia lamblia Alpha-tubulin 0.0048 0.0136 0.1663
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus tubulin alpha 0.0043 0.0112 0.0715
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0005 0.0024
Onchocerca volvulus 0.0086 0.0316 0.1468
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0005 0.0007
Brugia malayi orphan nuclear receptor NR2E1 0.0086 0.0316 0.1424
Loa Loa (eye worm) tubulin beta-1 chain 0.0043 0.0112 0.0506
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0022 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Echinococcus granulosus caspase 2 0.002 0.0006 0.0041
Loa Loa (eye worm) tubulin alpha 2 0.0029 0.0049 0.0223
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0086 0.0316 0.1424
Brugia malayi hypothetical protein 0.0022 0.0017 0.0077
Echinococcus multilocularis PHD finger protein rhinoceros 0.0037 0.0088 0.0121
Echinococcus granulosus tubulin alpha 3 chain 0.0048 0.0136 0.0863
Plasmodium vivax glutathione reductase, putative 0.0043 0.0114 0.5976
Echinococcus granulosus Tubulin beta 2C chain 0.0043 0.0112 0.0715
Echinococcus multilocularis caspase 0.002 0.0006 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0114 0.0515
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0077 0.027 0.0374
Schistosoma mansoni nuclear hormone receptor 0.0183 0.0766 0.4875
Loa Loa (eye worm) tubulin beta-2A chain 0.0043 0.0112 0.0506
Trypanosoma brucei importin beta-1 subunit, putative 0.0021 0.0012 0.0055
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0183 0.0766 0.4875
Plasmodium vivax tubulin beta chain, putative 0.0043 0.0112 0.5879
Giardia lamblia Beta tubulin 0.0043 0.0112 0.1377
Echinococcus multilocularis caspase 2 0.002 0.0006 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0229 0.0229
Toxoplasma gondii alpha tubulin TUBA1 0.0048 0.0136 0.592
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0017 0.0108
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus multilocularis RUN 0.0027 0.004 0.0055
Echinococcus multilocularis tubulin alpha 3 chain 0.0048 0.0136 0.0188
Echinococcus granulosus tubulin alpha chain 0.0048 0.0136 0.0863
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0109 0.0422 0.0422
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0496 0.2217 1
Loa Loa (eye worm) BEN-1 protein 0.0043 0.0112 0.0506
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0036 0.0229
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0124 0.0791
Entamoeba histolytica tubulin gamma chain 0.0043 0.0112 0.1321
Giardia lamblia Fructose-bisphosphate aldolase 0.0194 0.0815 1
Plasmodium falciparum alpha tubulin 2 0.0048 0.0136 1
Trypanosoma brucei epsilon tubulin 0.0043 0.0112 0.0506
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0005 0.0392
Echinococcus multilocularis serotonin transporter 0.0155 0.0633 0.0876
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0108 0.051
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0036 0.0229
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0022 0.01
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0022 0.0139
Brugia malayi hypothetical protein 0.0086 0.0316 0.1424
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.036 0.229
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Brugia malayi beta-lactamase family protein 0.0042 0.0108 0.0486
Trypanosoma brucei alpha tubulin, putative 0.0024 0.0026 0.0118
Loa Loa (eye worm) TAR-binding protein 0.0081 0.0291 0.1315
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0077
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0097 0.0439
Leishmania major DNA polymerase eta, putative 0.0023 0.0022 0.0098
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Echinococcus multilocularis Tubulin beta 2C chain 0.0043 0.0112 0.0155
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0108 0.051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Schistosoma mansoni sodium-dependent amino acid transporter 0.0026 0.0036 0.0229
Brugia malayi conserved hypotetical protein 0.0086 0.0316 0.1424
Echinococcus multilocularis tubulin subunit TubB 0.0048 0.0136 0.0188
Echinococcus granulosus beta tubulin 0.0043 0.0112 0.0715
Onchocerca volvulus 0.0026 0.0036 0.014
Echinococcus multilocularis jumonji domain containing protein 0.0052 0.0156 0.0215
Toxoplasma gondii hypothetical protein 0.0026 0.0036 0.1568
Brugia malayi hypothetical protein 0.024 0.1027 0.4634
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.0117 0.0162
Onchocerca volvulus 0.0086 0.0316 0.1468
Loa Loa (eye worm) tubulin alpha chain 0.0048 0.0136 0.0611
Schistosoma mansoni hypothetical protein 0.0037 0.0088 0.0558
Trypanosoma brucei alpha tubulin 0.0048 0.0136 0.0611
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0183 0.0766 0.4875
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus multilocularis p2X purinoceptor 4 0.003 0.0053 0.0073
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0036 0.0229
Loa Loa (eye worm) tubulin beta-4 chain 0.0043 0.0112 0.0506
Echinococcus granulosus Tubulin beta 2C chain 0.0043 0.0112 0.0715
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0026 0.0036 0.005
Plasmodium vivax tubulin alpha chain, putative 0.0048 0.0136 0.7097
Schistosoma mansoni jumonji domain containing protein 0.0097 0.0366 0.2331
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0183 0.0766 0.3454
Plasmodium falciparum phd finger protein, putative 0.0037 0.0088 0.6467
Echinococcus granulosus RUN 0.0027 0.004 0.0255
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0108 0.0108
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0155 0.0633 0.2854
Echinococcus granulosus thyroid hormone receptor alpha 0.0086 0.0316 0.201
Trypanosoma cruzi alpha tubulin, putative 0.0048 0.0136 0.0611
Brugia malayi hypothetical protein 0.0027 0.004 0.0181
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0122 0.0483 0.3076
Schistosoma mansoni nuclear hormone receptor 0.0086 0.0316 0.201
Schistosoma mansoni tubulin subunit epsilon 0.0043 0.0112 0.0715
Echinococcus multilocularis Polycystic kidney disease protein 0.0027 0.004 0.0055
Onchocerca volvulus 0.0026 0.0036 0.014
Onchocerca volvulus 0.0183 0.0766 0.3605
Plasmodium vivax hypothetical protein, conserved 0.002 0.0006 0.034
Schistosoma mansoni survival motor neuron protein 0.0049 0.0141 0.0898
Echinococcus multilocularis tubulin alpha 3 chain 0.0048 0.0136 0.0188
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Toxoplasma gondii HEAT repeat-containing protein 0.0021 0.0012 0.0531
Echinococcus granulosus tubulin alpha 1C chain 0.0048 0.0136 0.0863
Brugia malayi ecdysone receptor 0.0086 0.0316 0.1424
Trichomonas vaginalis tubulin beta chain, putative 0.0043 0.0112 0.0531
Schistosoma mansoni tar DNA-binding protein 0.0081 0.0291 0.1856
Loa Loa (eye worm) alpha-tubulin 0.0048 0.0136 0.0611
Schistosoma mansoni coup transcription factor 0.0183 0.0766 0.4875
Schistosoma mansoni P2X receptor subunit 0.003 0.0053 0.0338
Brugia malayi Steroid receptor seven-up type 2 0.0183 0.0766 0.3454
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Trypanosoma brucei beta tubulin 0.0043 0.0112 0.0506
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0022 0.0098
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Toxoplasma gondii PHD-finger domain-containing protein 0.0037 0.0088 0.3828
Echinococcus multilocularis tubulin alpha chain 0.0048 0.0136 0.0188
Brugia malayi Doublecortin family protein 0.0027 0.004 0.0181
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0036 0.1879
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0183 0.0766 0.4875
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0022 0.01
Onchocerca volvulus 0.006 0.0191 0.0876
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0109 0.0422 0.0422
Schistosoma mansoni hypothetical protein 0.0226 0.0963 0.6134
Echinococcus multilocularis lipoxygenase domain containing protein 0.0027 0.004 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0191 0.1216
Entamoeba histolytica tubulin alpha chain, putative 0.0048 0.0136 0.1608
Loa Loa (eye worm) hypothetical protein 0.0155 0.0633 0.2854
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0036 0.0229
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0006 0.0284
Plasmodium falciparum amino acid transporter, putative 0.0026 0.0036 0.2648
Brugia malayi Importin beta-1 subunit 0.0021 0.0012 0.0055
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Loa Loa (eye worm) tubulin alpha-2 chain 0.0048 0.0136 0.0611
Leishmania major metacaspase, putative 0.002 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Brugia malayi jmjC domain containing protein 0.0045 0.0124 0.056
Echinococcus granulosus tubulin gamma 1 chain 0.0043 0.0112 0.0715
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0022 0.0022
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0108 0.0686
Schistosoma mansoni rab6-interacting 0.0027 0.004 0.0255
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0183 0.0766 0.106
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0081 0.0291 0.1315
Onchocerca volvulus 0.0042 0.0108 0.0481
Echinococcus granulosus alpha tubulin 0.0048 0.0136 0.0863
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0029 0.0049 0.0223
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0183 0.0766 0.4875
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Plasmodium vivax multidomain scavenger receptor, putative 0.0027 0.004 0.2097
Loa Loa (eye worm) tubulin alpha 2 0.0029 0.0049 0.0223
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.1568
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0064 0.0406
Leishmania major hypothetical protein, conserved 0.0042 0.0108 0.0486
Trypanosoma brucei alpha tubulin 0.0048 0.0136 0.0611
Toxoplasma gondii alpha-tubulin I, putative 0.0048 0.0136 0.592
Echinococcus granulosus Tubulin beta 2C chain 0.0043 0.0112 0.0715
Brugia malayi nuclear receptor NHR-67 0.0086 0.0316 0.1424
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0028 0.0046 0.0292
Brugia malayi Cell death protein 3 precursor 0.002 0.0006 0.0029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0006 0.0041
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0086 0.0316 0.201
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.0162
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0043 0.0112 0.0155
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0181
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0108 0.0108
Mycobacterium ulcerans histidinol dehydrogenase 0.217 1 1
Echinococcus multilocularis glutamate receptor 2 0.0032 0.0064 0.0088
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0108 0.0108
Echinococcus granulosus nmda type glutamate receptor 0.007 0.0237 0.1508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0183 0.0766 0.3454
Schistosoma mansoni tar DNA-binding protein 0.0081 0.0291 0.1856
Entamoeba histolytica tubulin alpha-1 chain 0.0048 0.0136 0.1608
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0037 0.0088 0.0558
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0183 0.0766 0.4875
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0191 0.1216
Echinococcus granulosus Tubulin beta 2C chain 0.0043 0.0112 0.0715
Trypanosoma brucei metacaspase 0.002 0.0006 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Echinococcus granulosus Tubulin beta 2C chain 0.0043 0.0112 0.0715
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0181 0.0817
Trichomonas vaginalis tubulin gamma chain, putative 0.0043 0.0112 0.0531
Loa Loa (eye worm) thioredoxin reductase 0.0043 0.0114 0.0515
Trypanosoma brucei metacaspase 5, putative 0.002 0.0006 0.0029
Loa Loa (eye worm) BEN-1 protein 0.0043 0.0112 0.0506
Brugia malayi photoreceptor-specific nuclear receptor 0.0183 0.0766 0.3454
Trichomonas vaginalis tubulin epsilon chain, putative 0.0043 0.0112 0.0531
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0122 0.0483 0.0668
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0183 0.0766 0.106
Loa Loa (eye worm) hypothetical protein 0.0135 0.0543 0.2449
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0183 0.0766 0.3454
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0022 0.0022
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0086 0.0316 0.201
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Brugia malayi tubulin alpha chain - mouse 0.0048 0.0136 0.0611
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0108 0.5642
Echinococcus multilocularis beta tubulin 0.0043 0.0112 0.0155
Trichomonas vaginalis tubulin, putative 0.0024 0.0026 0.0124
Trypanosoma brucei epsilon tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Schistosoma mansoni hypothetical protein 0.0039 0.0097 0.0619
Echinococcus multilocularis p2X purinoceptor 4 0.003 0.0053 0.0073
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0086 0.0316 0.201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Schistosoma mansoni importin beta-1 0.0021 0.0012 0.0077
Echinococcus granulosus Nuclear hormone receptor HR96 0.0086 0.0316 0.201
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus geminin 0.0357 0.1571 1
Schistosoma mansoni transcription factor LCR-F1 0.0021 0.0011 0.0072
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0098 0.0371 0.0371
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0086 0.0316 0.0437
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0136 0.0641
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0022 0.0204
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.1568
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0183 0.0766 0.3454
Entamoeba histolytica tubulin family protein 0.0043 0.0112 0.1321
Schistosoma mansoni tubulin subunit beta 0.0043 0.0112 0.0715
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus multilocularis tubulin alpha 0.0043 0.0112 0.0155
Schistosoma mansoni DNA polymerase eta 0.0023 0.0022 0.0139
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0005 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0182 0.0821
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0028 0.0046 0.0292
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0183 0.0766 0.3605
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0028 0.0046 0.0064
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0036 0.0229
Trypanosoma brucei beta tubulin 0.0043 0.0112 0.0506
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0098 0.0371 0.0371
Loa Loa (eye worm) DR-78 0.0086 0.0316 0.1424
Brugia malayi Tubulin beta chain 0.0024 0.0026 0.0118
Loa Loa (eye worm) hypothetical protein 0.0155 0.0633 0.2854
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Loa Loa (eye worm) hypothetical protein 0.0352 0.1548 0.6981
Schistosoma mansoni alpha tubulin 0.0048 0.0136 0.0863
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0022 0.0022
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0162 0.0669 0.0925
Brugia malayi nuclear receptor RXR 0.0086 0.0316 0.1424
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0136 0.0641
Brugia malayi Nuclear hormone receptor-like 1 0.0097 0.0364 0.1641
Entamoeba histolytica hypothetical protein 0.0021 0.0011 0.0073
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0086 0.0316 0.0437
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Mycobacterium ulcerans hypothetical protein 0.0042 0.0108 0.0108
Trichomonas vaginalis tubulin alpha chain, putative 0.0024 0.0026 0.0124
Trypanosoma brucei metacaspase MCA3 0.002 0.0006 0.0029
Brugia malayi Nuclear hormone receptor E75 0.0086 0.0316 0.1424
Toxoplasma gondii thioredoxin reductase 0.0043 0.0114 0.4985
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0022 0.0022
Trypanosoma brucei beta tubulin 0.0043 0.0112 0.0506
Trypanosoma brucei Metacaspase-4 0.002 0.0006 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Plasmodium falciparum importin beta, putative 0.0021 0.0012 0.0897
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0229 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0038 0.0092 0.0587
Leishmania major DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0005 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0183 0.0766 0.106
Brugia malayi Glutamate receptor 1 precursor 0.0032 0.0064 0.0288
Echinococcus multilocularis tubulin alpha 1C chain 0.0048 0.0136 0.0188
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Mycobacterium tuberculosis Probable dehydrogenase 0.0098 0.0371 0.0371
Loa Loa (eye worm) RNA binding protein 0.0081 0.0291 0.1315
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0183 0.0766 0.3454
Trypanosoma brucei metacaspase MCA2 0.002 0.0006 0.0029
Trichomonas vaginalis tubulin alpha chain, putative 0.0024 0.0026 0.0124
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0183 0.0766 0.4875
Loa Loa (eye worm) beta-tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus glutamate receptor 2 0.0038 0.0092 0.0587
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Loa Loa (eye worm) hypothetical protein 0.0199 0.0839 0.3786
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0029 0.0049 0.0234
Echinococcus granulosus p2X purinoceptor 4 0.003 0.0053 0.0338
Giardia lamblia Beta tubulin 0.0043 0.0112 0.1377
Brugia malayi Pre-SET motif family protein 0.006 0.0191 0.0861
Echinococcus multilocularis tumor protein p63 0.0253 0.109 0.1508
Brugia malayi Nuclear hormone receptor E75 0.0086 0.0316 0.1424
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0022 0.0139
Echinococcus multilocularis peroxisome assembly protein 26 0.0048 0.0136 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0183 0.0766 0.3454
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0006 0.0041
Echinococcus multilocularis hypothetical protein 0.0048 0.0136 0.0188
Schistosoma mansoni hypothetical protein 0.0049 0.0141 0.0898
Leishmania major epsilon tubulin, putative 0.0043 0.0112 0.0506
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0191 0.8342
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0108 0.0108
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0022 0.0098
Giardia lamblia Beta tubulin 0.0043 0.0112 0.1377
Echinococcus granulosus tar DNA binding protein 0.0081 0.0291 0.1856
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0022 0.0098
Trypanosoma brucei alpha tubulin 0.0048 0.0136 0.0611
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0031
Echinococcus multilocularis importin subunit beta 1 0.0021 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.024 0.1027 0.4634
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0022 0.0103
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0026 0.0036 0.005
Brugia malayi beta-tubulin, identical 0.0043 0.0112 0.0506
Schistosoma mansoni tubulin subunit beta 0.0043 0.0112 0.0715
Echinococcus granulosus peregrin 0.0037 0.0088 0.0558
Schistosoma mansoni tar DNA-binding protein 0.0081 0.0291 0.1856
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0162 0.0669 0.4258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0183 0.0766 0.3454
Loa Loa (eye worm) tubulin alpha-3 chain 0.0024 0.0023 0.0105
Echinococcus granulosus Tubulin alpha 1 chain 0.0048 0.0136 0.0863
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0005 0.0005
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus dna polymerase kappa 0.0023 0.0022 0.0139
Onchocerca volvulus 0.0049 0.0141 0.0638
Brugia malayi nuclear hormone receptor family member nhr-6 0.0086 0.0316 0.1424
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0022 0.003
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0038 0.0092 0.0128
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0028 0.0046 0.0292
Loa Loa (eye worm) hypothetical protein 0.0037 0.0086 0.0388
Echinococcus granulosus tubulin beta 1 chain 0.0043 0.0112 0.0715
Entamoeba histolytica hypothetical protein 0.0021 0.0011 0.0073
Echinococcus multilocularis tubulin alpha chain 0.0048 0.0136 0.0188
Plasmodium vivax thioredoxin reductase, putative 0.0043 0.0114 0.5976
Brugia malayi glutathione reductase 0.0043 0.0114 0.0515
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0024 0.0023 0.011
Brugia malayi nuclear receptor NHR-88 0.0086 0.0316 0.1424
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0183 0.0766 0.106
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.1568
Trichomonas vaginalis tubulin beta chain, putative 0.0024 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0183 0.0766 0.3454
Trichomonas vaginalis tubulin epsilon chain, putative 0.0048 0.0136 0.0641
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0109 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0486
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0191 0.0264
Echinococcus multilocularis Tubulin beta 2C chain 0.0043 0.0112 0.0155
Echinococcus multilocularis tubulin epsilon chain 0.0043 0.0112 0.0155
Leishmania major cytochrome p450-like protein 0.0023 0.0022 0.01
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0136 0.0641
Brugia malayi Glutamate receptor 2 precursor 0.0032 0.0064 0.0288
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.036 0.0498
Brugia malayi Cytochrome P450 family protein 0.0023 0.0022 0.01
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0006 0.0041
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0183 0.0766 0.4875
Mycobacterium tuberculosis Conserved protein 0.0042 0.0108 0.0108
Trypanosoma brucei beta tubulin 0.0043 0.0112 0.0506
Loa Loa (eye worm) alpha-tubulin 0.0048 0.0136 0.0611
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0029
Toxoplasma gondii ABC1 family protein 0.0042 0.0108 0.4706
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0105
Echinococcus granulosus p2X purinoceptor 4 0.003 0.0053 0.0338
Mycobacterium ulcerans beta-lactamase 0.0042 0.0108 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0088 0.459
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Brugia malayi Tubulin alpha-2 chain 0.0048 0.0136 0.0611
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Brugia malayi steroid hormone receptor 0.0183 0.0766 0.3454
Echinococcus granulosus tubulin subunit beta 0.0043 0.0112 0.0715
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0086 0.0316 0.1468
Schistosoma mansoni tubulin subunit beta 0.0043 0.0112 0.0715
Brugia malayi Tubulin beta-1 chain 0.0043 0.0112 0.0506
Loa Loa (eye worm) solute carrier family 6 member 4 0.0155 0.0633 0.2854
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0097 0.0364 0.1641
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0006 0.0029
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0022 0.01
Schistosoma mansoni alpha tubulin 0.0048 0.0136 0.0863
Loa Loa (eye worm) hypothetical protein 0.0097 0.0364 0.1641
Echinococcus granulosus tubulin alpha chain 0.0048 0.0136 0.0863
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.0255
Trypanosoma cruzi beta tubulin, putative 0.0043 0.0112 0.0506
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0072
Echinococcus multilocularis tubulin beta 1 chain 0.0043 0.0112 0.0155
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0005 0.0024
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0229 0.1458
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0191 0.1216
Trichomonas vaginalis tubulin, putative 0.0043 0.0112 0.0531
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.0017 0.005
Schistosoma mansoni sodium/chloride dependent transporter 0.0155 0.0633 0.4029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0229 0.1458
Loa Loa (eye worm) tubulin beta chain 0.0043 0.0112 0.0506
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Loa Loa (eye worm) hypothetical protein 0.0097 0.0364 0.1641
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0006 0.0284
Schistosoma mansoni titin 0.0022 0.0017 0.0108
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0223 0.0952 0.0952
Brugia malayi Tubulin gamma chain 0.0043 0.0112 0.0506
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0108 0.0486
Echinococcus multilocularis caspase 8 0.002 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0076 0.0268 0.1207
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0136 0.0641
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0194 0.0815 1
Trypanosoma cruzi tubulin gamma chain 0.0043 0.0112 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0031
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Loa Loa (eye worm) nuclear hormone receptor 0.0086 0.0316 0.1424
Echinococcus granulosus tubulin alpha 3 chain 0.0048 0.0136 0.0863
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0108 0.0486
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0108 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Schistosoma mansoni loxhd1 0.0027 0.004 0.0255
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0108 0.0486
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0486
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0086 0.0316 0.1468
Echinococcus granulosus dna polymerase eta 0.0023 0.0022 0.0139
Brugia malayi Nuclear hormone receptor-like 1 0.0183 0.0766 0.3454
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0005 0.0024
Trichomonas vaginalis tubulin alpha chain, putative 0.0024 0.0026 0.0124
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0022 0.0022
Schistosoma mansoni lipoxygenase 0.0114 0.0442 0.2812
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0183 0.0766 0.3454
Echinococcus multilocularis glutamate receptor NMDA 0.0063 0.0208 0.0288
Leishmania major C-8 sterol isomerase-like protein 0.0496 0.2217 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0095 0.0354 0.0354
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0005 0.0025
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0229 0.0317
Giardia lamblia DINP protein human, muc B family 0.0023 0.0022 0.0268
Schistosoma mansoni alpha tubulin 0.0048 0.0136 0.0863
Toxoplasma gondii beta-tubulin, putative 0.0043 0.0112 0.4904
Mycobacterium leprae Probable lipase LipE 0.0042 0.0108 0.0108
Toxoplasma gondii PHD-finger domain-containing protein 0.0037 0.0088 0.3828
Echinococcus granulosus lipoxygenase domain containing protein 0.0027 0.004 0.0255
Schistosoma mansoni nuclear receptor 0.0086 0.0316 0.201
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0098 0.0371 0.0371
Echinococcus granulosus importin subunit beta 1 0.0021 0.0012 0.0077
Entamoeba histolytica hypothetical protein 0.0021 0.0011 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0183 0.0766 0.3454
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0064 0.0406
Brugia malayi tubulin alpha-2 chain 0.0048 0.0136 0.0611
Trypanosoma brucei C-8 sterol isomerase, putative 0.0496 0.2217 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0108 0.051
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus multilocularis geminin 0.0357 0.1571 0.2173
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1574 0.7227 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0229 0.1033
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.1027 0.1422
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0136 0.0641
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.0117 0.0744
Schistosoma mansoni hypothetical protein 0.0357 0.1571 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0005 0.0034
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0194 0.0815 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0005 0.0024
Echinococcus multilocularis lipoxygenase domain containing protein 0.0027 0.004 0.0055
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0048 0.0136 0.0641
Echinococcus multilocularis nmda type glutamate receptor 0.0075 0.0264 0.0365
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0086 0.0316 0.0437
Loa Loa (eye worm) PHD-finger family protein 0.0037 0.0088 0.0395
Brugia malayi RNA, U transporter 1 0.006 0.0193 0.0872
Echinococcus multilocularis Tubulin beta 2C chain 0.0043 0.0112 0.0155
Echinococcus granulosus beta tubulin 0.0043 0.0112 0.0715
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0022 0.01
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0005 0.0065
Schistosoma mansoni nuclear receptor 0.0086 0.0316 0.201
Onchocerca volvulus 0.0042 0.0108 0.0481
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus granulosus caspase 8 0.002 0.0006 0.0041
Schistosoma mansoni tubulin subunit beta 0.0043 0.0112 0.0715
Echinococcus multilocularis tubulin alpha chain 0.0048 0.0136 0.0188
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0181
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0021 0.0011 0.0016
Schistosoma mansoni tubulin subunit gamma 0.0043 0.0112 0.0715
Schistosoma mansoni RAR-like nuclear receptor 0.0183 0.0766 0.4875
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0183 0.0766 0.3454
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0108 0.0486
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0108 0.051
Loa Loa (eye worm) norepinephrine transporter 0.0155 0.0633 0.2854
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0183 0.0766 0.3454
Echinococcus multilocularis tubulin alpha chain 0.0048 0.0136 0.0188
Trichomonas vaginalis esterase, putative 0.0042 0.0108 0.051
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0006 0.0041
Echinococcus granulosus Tubulin alpha 1 chain 0.0048 0.0136 0.0863
Plasmodium falciparum tubulin beta chain 0.0043 0.0112 0.8284
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0055
Trichomonas vaginalis tubulin gamma chain, putative 0.0043 0.0112 0.0531
Onchocerca volvulus Alhambra homolog 0.0037 0.0088 0.0385
Onchocerca volvulus 0.0026 0.0036 0.014
Echinococcus multilocularis peregrin 0.0037 0.0088 0.0121
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0226 0.0963 0.4345
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0038 0.0092 0.0587
Echinococcus granulosus glutamate receptor 2 0.0026 0.0037 0.0234
Brugia malayi hypothetical protein 0.0086 0.0316 0.1424
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0097 0.0364 0.0504
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Plasmodium falciparum LCCL domain-containing protein 0.0027 0.004 0.2955
Trypanosoma brucei unspecified product 0.0023 0.0022 0.0098
Echinococcus granulosus tubulin epsilon chain 0.0043 0.0112 0.0715
Schistosoma mansoni glutamate receptor NMDA 0.0102 0.0387 0.2463
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Plasmodium falciparum alpha tubulin 1 0.0048 0.0136 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0086 0.0316 0.0437
Loa Loa (eye worm) steroid hormone receptor 0.0183 0.0766 0.3454
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0229 0.0229
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0183 0.0766 0.3454
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0098 0.0371 0.0371
Onchocerca volvulus 0.0155 0.0633 0.2973
Brugia malayi RNA binding protein 0.0081 0.0291 0.1315
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Entamoeba histolytica tubulin family protein 0.0043 0.0112 0.1321
Loa Loa (eye worm) serotonin transporter b 0.0155 0.0633 0.2854
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0064 0.0406
Echinococcus granulosus survival motor neuron protein 1 0.024 0.1027 0.6541
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0267 0.1153 0.1153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Brugia malayi nuclear receptor NHR-88 0.0183 0.0766 0.3454
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.0162
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0005 0.0278
Trypanosoma brucei alpha tubulin 0.0048 0.0136 0.0611
Loa Loa (eye worm) glutamate receptor 2 0.0032 0.0064 0.0288
Schistosoma mansoni zinc finger protein 0.0086 0.0316 0.201
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Mycobacterium tuberculosis Conserved protein 0.0042 0.0108 0.0108
Echinococcus granulosus p2X purinoceptor 4 0.003 0.0053 0.0338
Onchocerca volvulus 0.0037 0.0086 0.0377
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0183 0.0766 0.3454
Plasmodium falciparum transporter, putative 0.0026 0.0036 0.2648
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0086 0.0316 0.1424
Plasmodium vivax importin-beta 2, putative 0.0021 0.0012 0.0637
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0026 0.0036 0.0162
Echinococcus granulosus ecdysone induced protein 78C 0.0183 0.0766 0.4875
Onchocerca volvulus 0.0027 0.004 0.0159
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Schistosoma mansoni ap endonuclease 0.002 0.0005 0.0034
Trypanosoma cruzi epsilon tubulin, putative 0.0043 0.0112 0.0506
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0486
Echinococcus multilocularis ecdysone induced protein 78C 0.0183 0.0766 0.106
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Onchocerca volvulus 0.0024 0.0026 0.0093
Schistosoma mansoni polycystin 1-related 0.0027 0.004 0.0255
Echinococcus multilocularis lysine specific demethylase 5A 0.0045 0.0124 0.0172
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0097 0.0364 0.2317
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0005 0.0065
Brugia malayi tailless protein 0.0086 0.0316 0.1424
Trypanosoma brucei trypanothione reductase 0.0043 0.0114 0.0515
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0026 0.0036 0.0229
Loa Loa (eye worm) glutamate receptor 1 0.0032 0.0064 0.0288
Plasmodium falciparum tubulin gamma chain 0.0043 0.0112 0.8284
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0097 0.0364 0.2317
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0005 0.0024
Schistosoma mansoni ap endonuclease 0.002 0.0005 0.0034
Echinococcus multilocularis p2X purinoceptor 4 0.003 0.0053 0.0073
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0022 0.003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0006 0.0284
Brugia malayi Nuclear hormone receptor-like 1 0.0097 0.0364 0.1641
Schistosoma mansoni tar DNA-binding protein 0.0081 0.0291 0.1856
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0108 0.0149
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0183 0.0766 0.4875
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0183 0.0766 0.3454
Schistosoma mansoni thyroid hormone receptor 0.0183 0.0766 0.4875
Onchocerca volvulus 0.0042 0.0108 0.0481
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0036 0.0229
Trypanosoma brucei tubulin gamma chain 0.0043 0.0112 0.0506
Schistosoma mansoni tubulin subunit alpha 0.0048 0.0136 0.0863
Trypanosoma brucei beta tubulin 0.0043 0.0112 0.0506
Onchocerca volvulus Huntingtin homolog 0.0076 0.0268 0.1239
Onchocerca volvulus 0.0027 0.004 0.0159
Echinococcus granulosus FTZ F1 alpha 0.0183 0.0766 0.4875
Echinococcus granulosus contactin 0.0022 0.0017 0.0108
Toxoplasma gondii exonuclease III APE 0.002 0.0005 0.0232
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0022 0.0098
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0155 0.0633 0.2854
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0028 0.0046 0.0207
Brugia malayi Tubulin alpha chain 0.0048 0.0136 0.0611
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0183 0.0766 0.4875
Giardia lamblia PHD finger protein 15 0.0037 0.0088 0.1075
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0022 0.0139
Loa Loa (eye worm) glutathione reductase 0.0043 0.0114 0.0515
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0183 0.0766 0.3454
Echinococcus multilocularis Tubulin alpha 1 chain 0.0048 0.0136 0.0188
Trypanosoma cruzi metacaspase, putative 0.002 0.0006 0.0029
Echinococcus granulosus tubulin subunit TubB 0.0048 0.0136 0.0863
Schistosoma mansoni P2X receptor subunit 0.003 0.0053 0.0338
Trichomonas vaginalis tubulin epsilon chain, putative 0.0043 0.0112 0.0531
Schistosoma mansoni tubulin subunit beta 0.0043 0.0112 0.0715
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0486
Echinococcus granulosus peroxisome assembly protein 26 0.0048 0.0136 0.0863
Brugia malayi Thioredoxin reductase 0.0043 0.0114 0.0515
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0026 0.0036 0.005
Brugia malayi Cytochrome P450 family protein 0.0058 0.0181 0.0817
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0162
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0005 0.0025
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0095 0.0354 0.0354
Plasmodium vivax tubulin epsilon chain, putative 0.0043 0.0112 0.5879
Plasmodium falciparum glutathione reductase 0.0043 0.0114 0.8421
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0036 0.0229
Schistosoma mansoni steroid hormone receptor ad4bp 0.0183 0.0766 0.4875
Schistosoma mansoni nuclear receptor nhr-48 0.0086 0.0316 0.201
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0022 0.01
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0191 0.1216
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.0162
Echinococcus granulosus lipoxygenase domain containing protein 0.0027 0.004 0.0255
Schistosoma mansoni tubulin subunit beta 0.0043 0.0112 0.0715
Plasmodium falciparum metacaspase 1 0.002 0.0006 0.0479
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0124 0.0791
Brugia malayi alpha-tubulin 0.0048 0.0136 0.0611
Echinococcus granulosus PHD finger protein rhinoceros 0.0037 0.0088 0.0558
Onchocerca volvulus 0.0473 0.2113 1
Echinococcus granulosus hemicentin 1 0.0022 0.0017 0.0108
Schistosoma mansoni P2X receptor subunit 0.003 0.0053 0.0338
Echinococcus multilocularis dna polymerase eta 0.0023 0.0022 0.003
Schistosoma mansoni hypothetical protein 0.0357 0.1571 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0183 0.0766 0.106
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0141 0.0636
Trypanosoma cruzi epsilon tubulin, putative 0.0043 0.0112 0.0506
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0095 0.0354 0.0354
Onchocerca volvulus Bile acid receptor homolog 0.0183 0.0766 0.3605
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0124 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0183 0.0766 0.3454
Onchocerca volvulus Protein ultraspiracle homolog 0.0183 0.0766 0.3605
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Toxoplasma gondii beta-1 tubulin, putative 0.0043 0.0112 0.4904
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0124 0.0791
Trypanosoma cruzi metacaspase, putative 0.002 0.0006 0.0029
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0097 0.0364 0.2317
Brugia malayi hypothetical protein 0.0027 0.004 0.0181
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0006 0.0041
Loa Loa (eye worm) hypothetical protein 0.0097 0.0364 0.1641
Brugia malayi hypothetical protein 0.0021 0.0011 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0108 0.0686
Echinococcus granulosus tumor protein p63 0.0253 0.109 0.694
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0108 0.0108
Brugia malayi nuclear hormone receptor 0.0183 0.0766 0.3454
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0036 0.005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0183 0.0766 0.4875
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0229 0.0229
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0183 0.0766 0.4875
Leishmania major gamma-tubulin 0.0043 0.0112 0.0506
Brugia malayi RNA recognition motif domain containing protein 0.0081 0.0291 0.1315
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0022 0.01
Treponema pallidum sodium- and chloride- dependent transporter 0.0155 0.0633 0.7764
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0136 0.0641
Echinococcus multilocularis snurportin 1 0.0226 0.0963 0.1333
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0223
Brugia malayi hypothetical protein 0.0026 0.0036 0.0162
Echinococcus granulosus tubulin alpha chain 0.0048 0.0136 0.0863
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus granulosus tubulin alpha chain 0.0048 0.0136 0.0863
Brugia malayi Tubulin alpha-2 chain 0.0048 0.0136 0.0611
Mycobacterium tuberculosis Probable reductase 0.0098 0.0371 0.0371
Echinococcus multilocularis nmda type glutamate receptor 0.007 0.0237 0.0328
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0036 0.0162
Echinococcus multilocularis tubulin subunit beta 0.0043 0.0112 0.0155
Brugia malayi hypothetical protein 0.0097 0.0364 0.1641
Echinococcus multilocularis tubulin gamma 1 chain 0.0043 0.0112 0.0155
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Plasmodium falciparum thioredoxin reductase 0.0043 0.0114 0.8421
Schistosoma mansoni tar DNA-binding protein 0.0081 0.0291 0.1856
Loa Loa (eye worm) tubulin gamma chain 0.0043 0.0112 0.0506
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0022 0.0098
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0064 0.0406
Schistosoma mansoni rab6-interacting 0.0027 0.004 0.0255
Schistosoma mansoni ATP-binding cassette transporter 0.0032 0.0064 0.0406
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Loa Loa (eye worm) beta-lactamase 0.0042 0.0108 0.0486
Brugia malayi jmjC domain containing protein 0.0122 0.0483 0.2179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0183 0.0766 0.3454
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Brugia malayi TAR-binding protein 0.0081 0.0291 0.1315
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0416 0.1846 0.8326
Schistosoma mansoni glutamate receptor NMDA 0.0077 0.027 0.1719
Trichomonas vaginalis tubulin epsilon chain, putative 0.0048 0.0136 0.0641
Loa Loa (eye worm) nuclear receptor NHR-67 0.0086 0.0316 0.1424
Echinococcus granulosus jumonji domain containing protein 0.0052 0.0156 0.0991
Echinococcus granulosus tubulin alpha 1C chain 0.0048 0.0136 0.0863
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0038 0.0092 0.0128
Echinococcus granulosus glutamate receptor NMDA 0.0063 0.0208 0.1327
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0108 0.0486
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0352 0.1548 0.6981
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0183 0.0766 0.106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0108 0.0108
Schistosoma mansoni memapsin-2 (A01 family) 0.032 0.14 0.8914
Mycobacterium tuberculosis Probable oxidoreductase 0.0109 0.0422 0.0422
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0183 0.0766 0.4875
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0038 0.0092 0.0587
Echinococcus granulosus caspase 0.002 0.0006 0.0041
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Echinococcus multilocularis beta tubulin 0.0043 0.0112 0.0155
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0021 0.0011 0.0072
Echinococcus multilocularis tubulin alpha chain 0.0048 0.0136 0.0188
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0229 0.0229
Echinococcus granulosus snurportin 1 0.0226 0.0963 0.6134
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0006 0.0009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0181 0.1151
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0229 0.1458
Schistosoma mansoni retinoic acid receptor RXR 0.0183 0.0766 0.4875
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0098
Loa Loa (eye worm) doublecortin family protein 0.0027 0.004 0.0181
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Loa Loa (eye worm) hypothetical protein 0.0097 0.0364 0.1641
Trichomonas vaginalis tubulin gamma chain, putative 0.0043 0.0112 0.0531
Mycobacterium tuberculosis Conserved protein 0.0042 0.0108 0.0108
Brugia malayi ecdysteroid receptor 0.0183 0.0766 0.3454
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0028 0.0046 0.0207
Echinococcus granulosus serotonin transporter 0.0155 0.0633 0.4029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0108 0.0686
Schistosoma mansoni P2X receptor subunit 0.003 0.0053 0.0338
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0191 0.0264
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0022 0.0098
Schistosoma mansoni tubulin subunit alpha 0.0048 0.0136 0.0863
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0031
Loa Loa (eye worm) hypothetical protein 0.0076 0.0268 0.1207
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0086 0.0316 0.201
Echinococcus granulosus tubulin alpha chain 0.0048 0.0136 0.0863
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0273 0.123
Trichomonas vaginalis tubulin alpha chain, putative 0.0043 0.0112 0.0531
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0028 0.0046 0.0064
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0108 0.0108
Echinococcus multilocularis Tubulin alpha 1 chain 0.0048 0.0136 0.0188
Entamoeba histolytica hypothetical protein 0.0021 0.0011 0.0073
Mycobacterium tuberculosis Probable histidinol dehydrogenase HisD (HDH) 0.217 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0136 0.0611
Giardia lamblia Alpha-tubulin 0.0048 0.0136 0.1663
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0064 0.0212 0.0955
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0486
Brugia malayi beta-lactamase 0.0042 0.0108 0.0486
Brugia malayi nuclear receptor RXR 0.0097 0.0364 0.1641
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0024 0.0026 0.0124
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0038 0.0092 0.0128
Loa Loa (eye worm) hypothetical protein 0.0086 0.0316 0.1424
Brugia malayi nuclear hormone receptor family member odr-7 0.0086 0.0316 0.1424
Trichomonas vaginalis set domain proteins, putative 0.0473 0.2113 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0043 0.0112 0.0155
Loa Loa (eye worm) hypothetical protein 0.0183 0.0766 0.3454
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus glutamate NMDA receptor subunit 0.0077 0.027 0.1719
Trichomonas vaginalis tubulin, putative 0.0024 0.0026 0.0124
Echinococcus multilocularis tar DNA binding protein 0.0081 0.0291 0.0403
Brugia malayi Pre-SET motif family protein 0.0416 0.1846 0.8326
Brugia malayi Bromodomain containing protein 0.0037 0.0088 0.0395
Brugia malayi Cytochrome P450 family protein 0.0023 0.0022 0.01
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Plasmodium vivax metacaspase 1, putative 0.002 0.0006 0.034
Echinococcus multilocularis hemicentin 1 0.0022 0.0017 0.0024
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0064 0.0406
Leishmania major trypanothione reductase 0.0043 0.0114 0.0515
Echinococcus granulosus tubulin beta 4A class IVa 0.0043 0.0112 0.0715
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0005 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0194 0.0815 0.3858
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0098 0.0371 0.0371
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0006 0.0031
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0038 0.0092 0.0587
Echinococcus multilocularis Tubulin beta 2C chain 0.0043 0.0112 0.0155
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0223 0.0952 0.0952
Loa Loa (eye worm) hypothetical protein 0.0039 0.0097 0.0439
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0043 0.0112 0.4904
Schistosoma mansoni cellular tumor antigen P53 0.0037 0.0086 0.0548
Brugia malayi hypothetical protein 0.0076 0.0268 0.1207
Loa Loa (eye worm) tubulin alpha chain 0.0048 0.0136 0.0611
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0182 0.0821
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0022 0.0098
Echinococcus granulosus nmda type glutamate receptor 0.0075 0.0264 0.168
Leishmania major beta tubulin 0.0043 0.0112 0.0506
Echinococcus granulosus Tubulin alpha 1 chain 0.0048 0.0136 0.0863
Trypanosoma cruzi metacaspase, putative 0.002 0.0006 0.0029
Brugia malayi hypothetical protein 0.0097 0.0364 0.1641
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0486
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0022 0.0103
Trypanosoma brucei epsilon tubulin 0.0043 0.0112 0.0506
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0022 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0028 0.0046 0.0292
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0086 0.0316 0.0437
Loa Loa (eye worm) hypothetical protein 0.0097 0.0364 0.1641
Plasmodium vivax amine transporter, putative 0.0026 0.0036 0.1879
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0155 0.0633 0.4029
Mycobacterium ulcerans lipase LipD 0.0042 0.0108 0.0108
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0022 0.0098
Leishmania major alpha tubulin 0.0048 0.0136 0.0611
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0183 0.0766 0.106
Plasmodium falciparum tubulin epsilon chain, putative 0.0043 0.0112 0.8284
Trypanosoma brucei importin beta-1 subunit, putative 0.0021 0.0012 0.0055
Toxoplasma gondii beta tubulin 0.0043 0.0112 0.4904
Loa Loa (eye worm) hypothetical protein 0.0496 0.2217 1
Schistosoma mansoni thyroid hormone receptor 0.0183 0.0766 0.4875
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0036 0.0229
Loa Loa (eye worm) hypothetical protein 0.0037 0.0088 0.0395
Echinococcus multilocularis tubulin alpha 1C chain 0.0048 0.0136 0.0188
Echinococcus granulosus nuclear receptor nhr 48 0.0086 0.0316 0.201
Echinococcus granulosus Nuclear hormone receptor HR96 0.0086 0.0316 0.201
Schistosoma mansoni nuclear hormone receptor 0.0086 0.0316 0.201
Echinococcus multilocularis nuclear receptor nhr 48 0.0086 0.0316 0.0437
Echinococcus multilocularis glutamate receptor 2 0.0026 0.0037 0.0051
Echinococcus multilocularis thyroid hormone receptor alpha 0.0183 0.0766 0.106
Echinococcus multilocularis Tubulin alpha 1 chain 0.0048 0.0136 0.0188
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0183 0.0766 0.4875
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0135 0.0543 0.2449
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0036 0.005
Loa Loa (eye worm) hypothetical protein 0.006 0.0191 0.0861
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0496 0.2217 1
Trypanosoma cruzi metacaspase, putative 0.002 0.0006 0.0029
Brugia malayi PHD-finger family protein 0.0037 0.0088 0.0395
Echinococcus granulosus Polycystic kidney disease protein 0.0027 0.004 0.0255
Plasmodium falciparum metacaspase-like protein 0.002 0.0006 0.0479
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0043 0.0114 0.0114
Trichomonas vaginalis tubulin alpha chain, putative 0.0043 0.0112 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0108 0.051
Plasmodium vivax tubulin gamma chain, putative 0.0043 0.0112 0.5879
Treponema pallidum fructose-bisphosphate aldolase 0.0194 0.0815 1
Giardia lamblia Gamma tubulin 0.0043 0.0112 0.1377
Echinococcus multilocularis glutamate receptor 2 0.0038 0.0092 0.0128
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0006 0.0029
Plasmodium vivax tubulin alpha chain, putative 0.0048 0.0136 0.7097

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 29 % Inhibitory activity against macrophage migration inhibitory factor tautomerase (MIF) at a concentration of 0.5 mM ChEMBL. 10576686
Inhibition (binding) = 35 % Inhibitory activity against macrophage migration inhibitory factor tautomerase (MIF) at a concentration of 0.5 mM ChEMBL. 10576686
Inhibition (binding) = 35 % Inhibitory activity against macrophage migration inhibitory factor tautomerase (MIF) at a concentration of 0.5 mM ChEMBL. 10576686

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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