Detailed information for compound 1907499

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 351.439 | Formula: C22H25NO3
  • H donors: 1 H acceptors: 2 LogP: 3.85 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1[C@H]2CC[C@H]([C@H]1CC2)OC(=O)C(c1ccccc1)(c1ccccc1)O
  • InChi: 1S/C22H25NO3/c1-23-18-12-14-19(23)20(15-13-18)26-21(24)22(25,16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-20,25H,12-15H2,1H3/t18-,19-,20-/m1/s1
  • InChiKey: LSJGAYNIIMEDLR-VAMGGRTRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine methyltransferase SET1 0.024 0.0749 0.4878
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0065 0.0209
Plasmodium vivax heat shock protein 86, putative 0.007 0.0178 0.0534
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.008 0.0593
Entamoeba histolytica hypothetical protein 0.0039 0.0074 0.0546
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Echinococcus multilocularis expressed protein 0.0028 0.0036 0.0036
Brugia malayi nuclear receptor NHR-67 0.0035 0.0063 0.0165
Treponema pallidum flavodoxin 0.0364 0.1162 1
Giardia lamblia Hypothetical protein 0.0843 0.2767 1
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0108 0.0306 0.0945
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0128 0.0128
Giardia lamblia Flavohemoprotein lateral transfer candidate 0.0108 0.0306 0.1069
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0015 0.0013
Schistosoma mansoni apoferritin-2 0.0028 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0058 0.1051
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0058 0.015
Echinococcus multilocularis replication factor c subunit 1 0.0022 0.0016 0.0016
Echinococcus multilocularis musashi 0.0029 0.0042 0.0042
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0058 0.0058
Brugia malayi jmjC domain containing protein 0.0127 0.0371 0.1153
Giardia lamblia Replication factor C, subunit 1 0.0022 0.0016 0.0017
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0533 0.1729 0.5527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0075 0.0196 0.0626
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0364 0.1162 0.3692
Schistosoma mansoni rab6-interacting 0.0021 0.0015 0.0015
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.0286 0.0286
Trichomonas vaginalis heat shock protein, putative 0.0056 0.013 0.0381
Brugia malayi Doublecortin family protein 0.0021 0.0015 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0173 0.0173
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0108 0.0306 0.0945
Schistosoma mansoni endoplasmin 0.007 0.0178 0.0178
Entamoeba histolytica type A flavoprotein, putative 0.0364 0.1162 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0322 0.1022 0.3268
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.08 0.08
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0063 0.0165
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0265 0.0831 0.0831
Brugia malayi nuclear hormone receptor family member nhr-6 0.0035 0.0063 0.0165
Brugia malayi Pre-SET motif family protein 0.0431 0.1388 0.4416
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0058 0.015
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0065 0.0173
Trypanosoma brucei oxidoreductase-protein, putative 0.0108 0.0306 0.0945
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0075 0.0196 0.0196
Loa Loa (eye worm) flavodoxin family protein 0.0364 0.1162 0.3715
Brugia malayi glutaminase DH11.1 0.0283 0.0893 0.2829
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0075 0.0196 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0075 0.0196 0.0592
Toxoplasma gondii heat shock protein HSP90 0.007 0.0178 0.11
Echinococcus granulosus nibrin 0.0022 0.0016 0.0016
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0035 0.0063 0.0063
Brugia malayi RNA binding protein 0.0068 0.0173 0.0517
Schistosoma mansoni coup transcription factor 0.0075 0.0196 0.0196
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0035 0.0063 0.0363
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0077 0.0211
Trypanosoma cruzi heat shock protein 90, putative 0.007 0.0178 0.0534
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Loa Loa (eye worm) hypothetical protein 0.0951 0.3129 1
Loa Loa (eye worm) hypothetical protein 0.022 0.0681 0.2177
Echinococcus granulosus cpg binding protein 0.0131 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0051
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0951 0.3129 1
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0022 0.0016 0.0015
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0951 0.3129 1
Trypanosoma cruzi FHA domain containing protein, putative 0.0022 0.0016 0.0015
Trypanosoma cruzi heat shock protein 90, putative 0.0056 0.013 0.0381
Entamoeba histolytica type A flavoprotein, putative 0.0364 0.1162 1
Trypanosoma brucei nitrate reductase, putative 0.0108 0.0306 0.0945
Mycobacterium ulcerans bacterioferritin BfrB 0.0028 0.0036 0.0079
Echinococcus multilocularis heat shock protein 90 0.007 0.0178 0.0178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0075 0.0196 0.0196
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Leishmania major heat shock protein, putative 0.0029 0.004 0.0091
Loa Loa (eye worm) glutaminase 0.0283 0.0893 0.2855
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0049
Schistosoma mansoni survival motor neuron protein 0.0052 0.0119 0.0119
Plasmodium falciparum JmjC domain-containing protein, putative 0.0034 0.0058 0.0149
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0951 0.3129 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0075 0.0196 0.1133
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0173 0.0173
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0447 0.1398
Trichomonas vaginalis heat shock protein, putative 0.0029 0.004 0.0091
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.0456 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.004 0.0077 0.0077
Echinococcus granulosus Nuclear hormone receptor HR96 0.0035 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0533 0.1729 0.5527
Onchocerca volvulus 0.0164 0.0494 0.2854
Echinococcus granulosus heat shock protein 90 0.007 0.0178 0.0178
Schistosoma mansoni phosphatidylserine receptor 0.0034 0.0058 0.0058
Echinococcus granulosus heat shock protein 90 0.0056 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0102 0.0285 0.0878
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0108 0.0306 0.0306
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Brugia malayi Nuclear hormone receptor-like 1 0.0075 0.0196 0.0592
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0128 0.0373
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0102 0.0285 0.0911
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0056 0.013 1
Brugia malayi jmjC domain containing protein 0.0134 0.0395 0.1229
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0027 0.0051
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0951 0.3129 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0075 0.0196 0.0196
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0074 0.0074
Brugia malayi topoisomerase 0.0022 0.0016 0.0015
Schistosoma mansoni jumonji domain containing protein 0.0034 0.0058 0.0058
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0022 0.0016 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0173 0.0173
Schistosoma mansoni hypothetical protein 0.0039 0.0074 0.0074
Schistosoma mansoni ferritin 0.0028 0.0036 0.0036
Onchocerca volvulus 0.0035 0.0063 0.0363
Echinococcus multilocularis nibrin 0.0022 0.0016 0.0016
Brugia malayi Pax transcription activation domain interacting protein 0.0022 0.0016 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0085
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0042 0.0097
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Loa Loa (eye worm) hypothetical protein 0.0054 0.0124 0.0395
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0108 0.0306 0.6624
Loa Loa (eye worm) diaphorase 0.0108 0.0306 0.0978
Schistosoma mansoni ap endonuclease 0.002 0.0011 0.0011
Brugia malayi heat shock protein 90 0.007 0.0178 0.0534
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0077 0.0211
Brugia malayi MH2 domain containing protein 0.0027 0.0033 0.0069
Echinococcus multilocularis ferritin 0.0028 0.0036 0.0036
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0108 0.0306 0.6624
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0246
Plasmodium falciparum endoplasmin, putative 0.0043 0.0087 0.0244
Schistosoma mansoni phd/f-box containing protein 0.0034 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0127 0.0371 0.0371
Brugia malayi hypothetical protein 0.0025 0.0027 0.0051
Echinococcus multilocularis RUN 0.0021 0.0015 0.0015
Brugia malayi Hsp90 protein 0.0029 0.004 0.0091
Brugia malayi Smad1 0.0027 0.0033 0.0069
Loa Loa (eye worm) transcription factor SMAD2 0.039 0.1251 0.3999
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Brugia malayi MH2 domain containing protein 0.039 0.1251 0.3978
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0159 0.0974
Loa Loa (eye worm) CXXC zinc finger family protein 0.0124 0.0359 0.1146
Schistosoma mansoni topbp1 0.0022 0.0016 0.0016
Echinococcus multilocularis GPCR, family 2 0.0102 0.0285 0.0285
Trypanosoma brucei heat shock protein 84, putative 0.0029 0.004 0.0091
Brugia malayi diaphorase 0.0108 0.0306 0.0945
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0162 0.0482
Onchocerca volvulus 0.0052 0.0119 0.0686
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0128 0.0128
Echinococcus multilocularis lysine specific demethylase 5A 0.0127 0.0371 0.0371
Schistosoma mansoni diflavin oxidoreductase 0.0472 0.1524 0.1524
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0058 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0162 0.0482
Echinococcus granulosus smad 0.0027 0.0033 0.0033
Loa Loa (eye worm) heat shock protein 75 0.0029 0.004 0.0127
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0162 0.3381
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0065 0.0357
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0058 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0075 0.0196 0.0592
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0178 0.0534
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0015
Echinococcus granulosus methionine synthase reductase 0.0587 0.191 0.191
Plasmodium vivax replication factor C subunit 1, putative 0.0022 0.0016 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0075 0.0196 0.0592
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0051
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.0456 1
Schistosoma mansoni hypothetical protein 0.1094 0.361 0.361
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0108 0.0306 0.0945
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Trichomonas vaginalis helicase, putative 0.0028 0.0038 0.0085
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0108 0.0306 0.0945
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0951 0.3129 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0011 0.0011
Onchocerca volvulus Protein ultraspiracle homolog 0.0075 0.0196 0.1133
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Schistosoma mansoni jumonji domain containing protein 0.0127 0.0371 0.0371
Echinococcus multilocularis cpg binding protein 0.0131 0.0382 0.0382
Echinococcus multilocularis nuclear receptor nhr 48 0.0035 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0085
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0364 0.1162 0.3692
Leishmania major NADH-dependent fumarate reductase-like protein 0.0108 0.0306 0.0945
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Schistosoma mansoni rab6-interacting 0.0021 0.0015 0.0015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0081 0.0081
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0058 0.0149
Toxoplasma gondii Hsp90 domain-containing protein 0.0029 0.004 0.0187
Mycobacterium ulcerans bacterioferritin BfrA 0.0028 0.0036 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0015
Leishmania major basic transcription factor 3a, putative 0.0036 0.0065 0.0173
Loa Loa (eye worm) nuclear receptor NHR-67 0.0035 0.0063 0.0201
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0058 0.0309
Echinococcus granulosus expressed protein 0.0028 0.0036 0.0036
Trichomonas vaginalis ferritin, putative 0.0028 0.0036 0.0079
Brugia malayi hypothetical protein 0.004 0.0077 0.0211
Echinococcus multilocularis lamin dm0 0.0029 0.0042 0.0042
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0015 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0075 0.0196 0.0196
Schistosoma mansoni zinc finger protein 0.0035 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0034 0.0058 0.0185
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0108 0.0306 0.1947
Echinococcus granulosus Niemann Pick C1 protein 0.0146 0.0433 0.0433
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0058 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0128 0.0373
Echinococcus granulosus lamin dm0 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.0091 0.029
Trypanosoma cruzi oxidoreductase-protein, putative 0.0108 0.0306 0.0945
Giardia lamblia Nitric oxide synthase, inducible 0.0843 0.2767 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0091 0.0254
Schistosoma mansoni jumonji/arid domain-containing protein 0.0134 0.0395 0.0395
Schistosoma mansoni glutaminase 0.0283 0.0893 0.0893
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0028 0.0036 0.0454
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0128 0.0373
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0038 0.0085
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0133
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0056 0.013 0.2671
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Treponema pallidum bacterioferrin (TpF1) 0.0028 0.0036 0.0214
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0364 0.1162 0.3692
Echinococcus granulosus lysine specific demethylase 5A 0.0134 0.0395 0.0395
Schistosoma mansoni nuclear receptor 0.0035 0.0063 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0075 0.0196 0.0626
Trypanosoma cruzi p450 reductase, putative 0.0108 0.0306 0.0945
Echinococcus multilocularis cytochrome b5 reductase 4 0.0108 0.0306 0.0306
Toxoplasma gondii heat shock protein 90, putative 0.007 0.0178 0.11
Trichomonas vaginalis sulfite reductase, putative 0.0951 0.3129 1
Leishmania major reductase, putative 0.0108 0.0306 0.0945
Onchocerca volvulus 0.0075 0.0196 0.1133
Schistosoma mansoni endoplasmin 0.007 0.0178 0.0178
Brugia malayi tailless protein 0.0035 0.0063 0.0165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0075 0.0196 0.0196
Echinococcus granulosus phd:f box containing protein 0.0034 0.0058 0.0058
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0055 0.0055
Brugia malayi MAP kinase sur-1 0.0055 0.0128 0.0373
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0035 0.0063 0.0063
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0075 0.0196 0.0592
Loa Loa (eye worm) histone methyltransferase 0.0041 0.008 0.0255
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.0291 0.0291
Brugia malayi hypothetical protein 0.004 0.0077 0.0211
Schistosoma mansoni topbp1 0.0022 0.0016 0.0016
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0056 0.013 0.013
Onchocerca volvulus Huntingtin homolog 0.0533 0.1729 1
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Mycobacterium tuberculosis Possible oxygenase 0.0108 0.0306 0.6624
Schistosoma mansoni heat shock protein 0.0029 0.004 0.004
Schistosoma mansoni smad1 5 8 and 0.0027 0.0033 0.0033
Schistosoma mansoni RAR-like nuclear receptor 0.0075 0.0196 0.0196
Loa Loa (eye worm) steroid hormone receptor 0.0075 0.0196 0.0626
Brugia malayi hypothetical protein 0.0021 0.0015 0.0013
Brugia malayi steroid hormone receptor 0.0075 0.0196 0.0592
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0022 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0034 0.0058 0.0307
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0056 0.013 0.2593
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0028 0.0036 0.0555
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0246
Brugia malayi Pre-SET motif family protein 0.0064 0.0159 0.0473
Echinococcus granulosus lamin 0.0029 0.0042 0.0042
Entamoeba histolytica hypothetical protein 0.0039 0.0074 0.0546
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0075 0.0196 0.0196
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0162 0.0994
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0016 0.0015
Brugia malayi hypothetical protein 0.0035 0.0063 0.0165
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0173 0.0551
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0022 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0051
Schistosoma mansoni thyroid hormone receptor 0.0075 0.0196 0.0196
Brugia malayi MH1 domain containing protein 0.0027 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.0456 0.1427
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Onchocerca volvulus 0.049 0.1586 0.9172
Schistosoma mansoni polycystin 1-related 0.0021 0.0015 0.0015
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0065 0.0173
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0033 0.0106
Schistosoma mansoni cpg binding protein 0.0124 0.0359 0.0359
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0102 0.0286 0.0914
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0058 0.0058
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0128 0.0373
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0108 0.0306 0.153
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0075 0.0196 0.0196
Echinococcus multilocularis phd:f box containing protein 0.0034 0.0058 0.0058
Echinococcus granulosus heat shock protein 0.007 0.0178 0.0178
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0029 0.004 0.023
Trypanosoma cruzi p450 reductase, putative 0.0951 0.3129 1
Leishmania major NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0011 0.0036
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0058 0.015
Brugia malayi nuclear hormone receptor 0.0035 0.0063 0.0165
Brugia malayi hypothetical protein 0.0022 0.0016 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0011 0.0011
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0022 0.0016 0.0041
Brugia malayi MH1 domain containing protein 0.0027 0.0033 0.0069
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Loa Loa (eye worm) hypothetical protein 0.0256 0.08 0.2558
Loa Loa (eye worm) nuclear hormone receptor 0.0035 0.0063 0.0201
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0469
Schistosoma mansoni lipoxygenase 0.0021 0.0015 0.0015
Brugia malayi jmjC domain containing protein 0.0034 0.0058 0.0149
Echinococcus granulosus tar DNA binding protein 0.0068 0.0173 0.0173
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0075 0.0196 0.0626
Schistosoma mansoni intermediate filament proteins 0.0029 0.0042 0.0042
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0108 0.0306 0.1947
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0178 0.0534
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Trypanosoma cruzi reductase, putative 0.0108 0.0306 0.0945
Echinococcus multilocularis ecdysone induced protein 78C 0.0075 0.0196 0.0196
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Onchocerca volvulus 0.0029 0.0042 0.0241
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0364 0.1162 0.3692
Leishmania major cytochrome P450 reductase, putative 0.0843 0.2767 0.8839
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0075 0.0196 0.0196
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Trypanosoma cruzi Heat shock protein 83, putative 0.007 0.0178 0.0534
Leishmania major hypothetical protein, conserved 0.0034 0.0058 0.0149
Plasmodium vivax JmjC domain containing protein 0.0034 0.0058 0.0149
Brugia malayi FAD binding domain containing protein 0.0587 0.191 0.6092
Trichomonas vaginalis glutaminase, putative 0.0283 0.0893 0.2829
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.0992 0.3561
Mycobacterium ulcerans oxidoreductase 0.0108 0.0306 0.0945
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0011 0.0011
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Leishmania major cytochrome-b5 reductase, putative 0.0108 0.0306 0.0945
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0092 0.0258
Echinococcus granulosus lysine specific demethylase 6a 0.0034 0.0058 0.0058
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0027 0.0051
Echinococcus granulosus dnaJ subfamily B 0.1763 0.5849 0.5849
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Treponema pallidum DNA ligase (lig) 0.0022 0.0016 0.0041
Trypanosoma cruzi nitrate reductase, putative 0.0108 0.0306 0.0945
Onchocerca volvulus 0.0064 0.0159 0.0918
Trypanosoma cruzi heat shock protein 85, putative 0.0056 0.013 0.0381
Loa Loa (eye worm) DR-78 0.0035 0.0063 0.0201
Brugia malayi conserved hypotetical protein 0.0035 0.0063 0.0165
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0178 0.1446
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0364 0.1162 0.3692
Echinococcus granulosus geminin 0.1094 0.361 0.361
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0035 0.0063 0.0063
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.008 0.0219
Brugia malayi nuclear hormone receptor 0.0075 0.0196 0.0592
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0364 0.1162 0.3692
Loa Loa (eye worm) glutaminase 2 0.0283 0.0893 0.2855
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0075 0.0196 0.0592
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0058 0.0058
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0128 0.0373
Brugia malayi hypothetical protein 0.0256 0.08 0.2531
Schistosoma mansoni hypothetical protein 0.022 0.0681 0.0681
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0075 0.0196 0.0196
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0091 0.029
Schistosoma mansoni ferritin light chain 0.0028 0.0036 0.0036
Loa Loa (eye worm) endoplasmin 0.007 0.0178 0.0568
Entamoeba histolytica type A flavoprotein, putative 0.0364 0.1162 1
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0162 0.0162
Schistosoma mansoni ferritin light chain 0.0028 0.0036 0.0036
Brugia malayi ecdysteroid receptor 0.0075 0.0196 0.0592
Echinococcus granulosus RUN 0.0021 0.0015 0.0015
Plasmodium vivax SET domain protein, putative 0.0064 0.0159 0.0473
Echinococcus multilocularis FTZ F1 alpha 0.0075 0.0196 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0159 0.0159
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0364 0.1162 0.3692
Loa Loa (eye worm) heat shock protein 90 0.007 0.0178 0.0568
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0162 0.0482
Brugia malayi Endoplasmin precursor 0.007 0.0178 0.0534
Echinococcus granulosus jumonji domain containing 1A 0.0034 0.0058 0.0058
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0051
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0022 0.0016 0.0393
Schistosoma mansoni heat shock protein 0.007 0.0178 0.0178
Onchocerca volvulus 0.0124 0.0359 0.2074
Echinococcus multilocularis expressed conserved protein 0.0096 0.0265 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0065 0.0173
Brugia malayi hypothetical protein 0.0022 0.0016 0.0015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0134 0.0395 0.0395
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0128 0.0373
Leishmania major NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.0992 0.8526
Schistosoma mansoni nuclear receptor 0.0035 0.0063 0.0063
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0038 0.0085
Onchocerca volvulus 0.0022 0.0016 0.0093
Schistosoma mansoni hypothetical protein 0.1763 0.5849 0.5849
Echinococcus multilocularis JmjC domain containing protein 4 0.0034 0.0058 0.0058
Schistosoma mansoni lipoxygenase 0.006 0.0144 0.0144
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0035 0.0063 0.0063
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0173 0.0173
Echinococcus multilocularis geminin 0.1094 0.361 0.361
Echinococcus multilocularis lamin 0.0029 0.0042 0.0042
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0102 0.0285 0.0285
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0058 0.0185
Brugia malayi hypothetical protein 0.0533 0.1729 0.5511
Plasmodium falciparum replication factor C subunit 1, putative 0.0022 0.0016 0.0015
Brugia malayi CHE-14 protein 0.0044 0.0091 0.0254
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0075 0.0196 0.0626
Mycobacterium ulcerans heat shock protein 90 0.0056 0.013 0.0381
Echinococcus multilocularis transcription factor btf3 0.0036 0.0065 0.0065
Schistosoma mansoni smad1 5 8 and 0.0027 0.0033 0.0033
Mycobacterium ulcerans electron transfer protein FdxB 0.0108 0.0306 0.0945
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0016 0.0015
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0092 0.0258
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0028 0.0036 0.2076
Schistosoma mansoni cpg binding protein 0.0131 0.0382 0.0382
Leishmania major hypothetical protein, conserved 0.0025 0.0027 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0049
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0102 0.0285 0.0285
Leishmania major NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0075 0.0196 0.0592
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0128 0.0769
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0022 0.0016 0.0015
Echinococcus multilocularis Niemann Pick C1 protein 0.0146 0.0433 0.0433
Plasmodium vivax heat shock protein 90, putative 0.0029 0.004 0.0091
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0029 0.004 0.004
Echinococcus granulosus mixed lineage leukemia protein mll 0.0033 0.0055 0.0055
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0128 0.0422
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0075 0.0196 0.0592
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0128 0.0408
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0038 0.0085
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2594 0.8636 0.8636
Brugia malayi latrophilin 2 splice variant baaae 0.022 0.0681 0.2149
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0587 0.191 0.191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0033 0.0033
Onchocerca volvulus 0.0021 0.0015 0.0089
Echinococcus multilocularis dnaJ subfamily B 0.1763 0.5849 0.5849
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.0992 0.8526
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0033 0.0055 0.0055
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.0058 0.0058
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0178 0.1446
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0028 0.0036 0.0555
Echinococcus granulosus histone acetyltransferase KAT2B 0.0146 0.0433 0.0433
Entamoeba histolytica hypothetical protein 0.0039 0.0074 0.0546
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.0992 0.8526
Schistosoma mansoni ap endonuclease 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Loa Loa (eye worm) hypothetical protein 0.0034 0.0058 0.0185
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0173 0.0551
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0178 0.0534
Echinococcus granulosus cytochrome b5 reductase 4 0.0108 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0092 0.0533
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0055 0.0055
Brugia malayi orphan nuclear receptor NR2E1 0.0035 0.0063 0.0165
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0091 0.0091
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0015 0.0049
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0951 0.3129 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0159 0.0159
Schistosoma mansoni cytochrome P450 reductase 0.0951 0.3129 0.3129
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0035 0.0063 0.0165
Brugia malayi intermediate filament protein 0.0029 0.0042 0.0097
Brugia malayi ecdysone receptor 0.0035 0.0063 0.0165
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0033 0.0033
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0029 0.004 0.0246
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0051
Brugia malayi hypothetical protein 0.0021 0.0015 0.0013
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0108 0.0306 0.0306
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0087 0.0244
Trypanosoma cruzi heat shock protein, putative 0.0029 0.004 0.0091
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0035 0.0063 0.0201
Plasmodium vivax heat shock protein, putative 0.0029 0.004 0.0091
Entamoeba histolytica hypothetical protein 0.0039 0.0074 0.0546
Schistosoma mansoni smad1 5 8 and 0.0027 0.0033 0.0033
Plasmodium vivax endoplasmin, putative 0.007 0.0178 0.0534
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Plasmodium vivax hypothetical protein, conserved 0.0364 0.1162 0.3692
Echinococcus granulosus transcription factor btf3 0.0036 0.0065 0.0065
Echinococcus granulosus nuclear receptor nhr 48 0.0035 0.0063 0.0063
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0035 0.0063 0.0063
Brugia malayi FAD binding domain containing protein 0.0951 0.3129 1
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0065 0.0173
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0058 0.015
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0015 0.0015
Echinococcus multilocularis endoplasmin 0.0056 0.013 0.013
Schistosoma mansoni DNA ligase IV 0.0022 0.0016 0.0016
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Mycobacterium ulcerans monooxygenase 0.0108 0.0306 0.0945
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0075 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0322 0.1022 0.3268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Trichomonas vaginalis heat shock protein, putative 0.0056 0.013 0.0381
Echinococcus granulosus JmjC domain containing protein 4 0.0034 0.0058 0.0058
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0015 0.0015
Chlamydia trachomatis sulfite reductase 0.0587 0.191 1
Brugia malayi MH2 domain containing protein 0.0027 0.0033 0.0069
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0108 0.0306 0.0945
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0035 0.0063 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0063 0.0063
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0075 0.0196 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Trypanosoma brucei Heat shock protein 83, putative 0.007 0.0178 0.0534
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0246
Brugia malayi DKFZp564C0469 protein 0.0022 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0447 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0128 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0159 0.0159
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0173 0.0173
Brugia malayi nuclear hormone receptor family member odr-7 0.0035 0.0063 0.0165
Brugia malayi jmjC domain containing protein 0.0034 0.0058 0.0149
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0077 0.0077
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0038 0.0085
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0029 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0058 0.0185
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0063 0.0165
Schistosoma mansoni Smad4 0.0027 0.0033 0.0033
Entamoeba histolytica hypothetical protein 0.0022 0.0016 0.0041
Brugia malayi jmjC domain containing protein 0.0034 0.0058 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0038 0.0085
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.004 0.0077 0.0246
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0178 0.0534
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Schistosoma mansoni lamin 0.0029 0.0042 0.0042
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0087
Brugia malayi hypothetical protein 0.0035 0.0063 0.0165
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.008 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0015
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0075 0.0196 0.0196
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0027 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0058 0.0149
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0022 0.0016 0.0031
Onchocerca volvulus Bile acid receptor homolog 0.0075 0.0196 0.1133
Echinococcus granulosus replication factor c subunit 1 0.0022 0.0016 0.0016
Echinococcus multilocularis Smad4 0.0027 0.0033 0.0033
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0035 0.0063 0.0363
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0034 0.0058 0.0307
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0843 0.2767 0.8839
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0128 0.0373
Echinococcus multilocularis thyroid hormone receptor alpha 0.0075 0.0196 0.0196
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.004 0.0077 0.0077
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0108 0.0306 0.0945
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0081 0.0081
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0075 0.0196 0.0196
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0173 0.0517
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0075 0.0196 0.0592
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.0078 0.0214
Loa Loa (eye worm) acetyltransferase 0.015 0.0447 0.143
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Trypanosoma brucei NADH-dependent fumarate reductase 0.0108 0.0306 0.0945
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0108 0.0306 0.0945
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.008 0.0248
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0058 0.015
Brugia malayi beta-NAC-like protein 0.0036 0.0065 0.0173
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0035 0.0063 0.0063
Toxoplasma gondii flavodoxin domain-containing protein 0.0472 0.1524 1
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0065 0.0173
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Loa Loa (eye worm) hypothetical protein 0.0064 0.0159 0.0508
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0085
Treponema pallidum heat shock protein 90 0.0056 0.013 0.1032
Schistosoma mansoni hypothetical protein 0.1094 0.361 0.361
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0033 0.0033
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0108 0.0306 0.0306
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0951 0.3129 0.3129
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0015 0.0015
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.08 0.08
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0128 0.0373
Loa Loa (eye worm) FAD binding domain-containing protein 0.0587 0.191 0.6106
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0075 0.0196 0.0196
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0015 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.3002 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0075 0.0196 0.0592
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0075 0.0196 0.0196
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.0395 0.1261
Leishmania major cytochrome-b5 reductase, putative 0.0108 0.0306 0.0945
Brugia malayi nuclear receptor RXR 0.004 0.0077 0.0211
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0092 0.0533
Echinococcus multilocularis heat shock protein 90 0.0056 0.013 0.013
Echinococcus granulosus Smad4 0.0027 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0102 0.0285 0.0285
Brugia malayi nuclear receptor RXR 0.0035 0.0063 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0015
Schistosoma mansoni chromosome transmission fidelity factor 0.0022 0.0016 0.0016
Treponema pallidum ferredoxin-NADP(+) reductase subunit alpha 0.0108 0.0306 0.256
Schistosoma mansoni transcription factor btf3 0.0036 0.0065 0.0065
Echinococcus multilocularis smad 0.0027 0.0033 0.0033
Brugia malayi TAR-binding protein 0.0068 0.0173 0.0517
Echinococcus multilocularis methionine synthase reductase 0.0587 0.191 0.191
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0034 0.0058 0.0149
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Echinococcus granulosus expressed conserved protein 0.0096 0.0265 0.0265
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0075 0.0196 0.0592
Schistosoma mansoni retinoic acid receptor RXR 0.0075 0.0196 0.0196
Echinococcus granulosus endoplasmin 0.0056 0.013 0.013
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0015 0.0015
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0128 0.0128
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0951 0.3129 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0027 0.0105
Onchocerca volvulus 0.0021 0.0015 0.0089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0075 0.0196 0.0196
Loa Loa (eye worm) FAD binding domain-containing protein 0.0951 0.3129 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0322 0.1022 0.3243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0075 0.0196 0.0626
Echinococcus granulosus thyroid hormone receptor alpha 0.0035 0.0063 0.0063
Onchocerca volvulus 0.0035 0.0063 0.0363
Mycobacterium tuberculosis Probable monooxygenase 0.0108 0.0306 0.6624
Schistosoma mansoni nuclear hormone receptor 0.0075 0.0196 0.0196
Echinococcus granulosus ferritin 0.0028 0.0036 0.0036
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Onchocerca volvulus 0.0108 0.0306 0.1769
Leishmania major nitrate reductase, putative 0.0108 0.0306 0.0945
Echinococcus granulosus ecdysone induced protein 78C 0.0075 0.0196 0.0196
Trichomonas vaginalis heat shock protein, putative 0.007 0.0178 0.0534
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0127
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0065 0.0173
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Plasmodium falciparum ferredoxin--NADP reductase 0.0108 0.0306 0.0945
Toxoplasma gondii flavodoxin domain-containing protein 0.0472 0.1524 1
Schistosoma mansoni thyroid hormone receptor 0.0075 0.0196 0.0196
Schistosoma mansoni ferritin 0.0028 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0102 0.0285 0.0285
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0022 0.0016 0.0015
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0128 0.0128
Trypanosoma brucei protein kinase, putative 0.0055 0.0128 0.0373
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.0286 0.0286
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0058 0.0058
Plasmodium vivax flavodoxin domain containing protein 0.0843 0.2767 0.8839
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0951 0.3129 0.3129
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0091 0.0091
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.008 0.008
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0127 0.0371 0.0371
Schistosoma mansoni patched 1 0.0044 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0052 0.0119 0.0119
Schistosoma mansoni smad 0.0027 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0075 0.0196 0.0592
Toxoplasma gondii ATPase, AAA family protein 0.0022 0.0016 0.0031
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0364 0.1162 0.3692
Schistosoma mansoni nuclear receptor nhr-48 0.0035 0.0063 0.0063
Brugia malayi CXXC zinc finger family protein 0.0124 0.0359 0.1114
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0065 0.0469
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0102 0.0285 0.0285
Brugia malayi nuclear receptor NHR-88 0.0035 0.0063 0.0165
Echinococcus granulosus intermediate filament protein 0.0029 0.0042 0.0042
Mycobacterium tuberculosis Probable oxidoreductase 0.0108 0.0306 0.6624
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0128 0.0373
Schistosoma mansoni cpg binding protein 0.0131 0.0382 0.0382
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0951 0.3129 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0033 0.0106
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0092 0.0258
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Brugia malayi isocitrate dehydrogenase 0.0034 0.0058 0.015
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0162 0.0162
Trichomonas vaginalis heat shock protein, putative 0.0056 0.013 0.0381
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0027 0.0051
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0951 0.3129 0.3129
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0108 0.0306 0.0945
Echinococcus multilocularis protein patched 0.0044 0.0091 0.0091
Schistosoma mansoni protein phosphatase 2C 0.0034 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0058 0.0309
Brugia malayi flavodoxin family protein 0.0951 0.3129 1
Schistosoma mansoni hypothetical protein 0.0102 0.0285 0.0285
Schistosoma mansoni loxhd1 0.0021 0.0015 0.0015
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0065 0.0173
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0058 0.0186
Brugia malayi jmjC domain containing protein 0.0034 0.0058 0.0149
Echinococcus multilocularis microtubule associated protein 2 0.3002 1 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0494 0.1578
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0364 0.1162 0.3692
Schistosoma mansoni ferritin 0.0028 0.0036 0.0036
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0364 0.1162 0.3692
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0102 0.0285 0.0285
Plasmodium falciparum heat shock protein 90 0.007 0.0178 0.0534
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0119 0.0344
Trichomonas vaginalis endoplasmin, putative 0.0043 0.0087 0.0244
Loa Loa (eye worm) latrophilin receptor protein 2 0.0102 0.0285 0.0911
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0144 0.0144
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0027 0.0051
Echinococcus multilocularis jumonji domain containing 1A 0.0034 0.0058 0.0058
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0092 0.0092
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0056 0.013 0.0381
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Echinococcus granulosus cytochrome b5 reductase 4 0.0108 0.0306 0.0306
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0058 0.015
Plasmodium falciparum nitric oxide synthase, putative 0.0951 0.3129 1
Loa Loa (eye worm) Smad1 0.0027 0.0033 0.0106
Brugia malayi Calcitonin receptor-like protein seb-1 0.0322 0.1022 0.3243
Schistosoma mansoni heat shock protein 0.007 0.0178 0.0178
Brugia malayi nuclear receptor NHR-88 0.0075 0.0196 0.0592
Echinococcus granulosus Nuclear hormone receptor HR96 0.0035 0.0063 0.0063
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0042 0.0133
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0108 0.0306 0.0978
Entamoeba histolytica type A flavoprotein, putative 0.0364 0.1162 1
Trichomonas vaginalis set domain proteins, putative 0.049 0.1586 0.5052
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0162 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0038 0.0085
Echinococcus multilocularis lysine specific demethylase 6a 0.0034 0.0058 0.0058
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0159 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0159 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Loa Loa (eye worm) RNA binding protein 0.0068 0.0173 0.0551
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0075 0.0196 0.0626
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0058 0.015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0038 0.0085
Leishmania major p450 reductase, putative 0.0951 0.3129 1
Onchocerca volvulus 0.0029 0.0042 0.0241
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0142 0.0142
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0022 0.0016 0.0015
Brugia malayi Latrophilin receptor protein 2 0.0102 0.0285 0.0878
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Schistosoma mansoni hypothetical protein 0.0021 0.0015 0.0015
Entamoeba histolytica type A flavoprotein, putative 0.0364 0.1162 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0075 0.0196 0.0196
Leishmania major NADH-cytochrome b5 reductase, putative 0.0108 0.0306 0.0945
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0102 0.0285 0.0285
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0065 0.0173
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.0286 0.088
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0159 0.0159
Giardia lamblia Heat shock protein HSP 90-alpha 0.0056 0.013 0.0431
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0063 0.0063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0159 0.0159
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0108 0.0306 0.0945
Schistosoma mansoni ferritin 0.0028 0.0036 0.0036
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0022 0.0016 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0063 0.0063
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0082 0.0226
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0051
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Leishmania major hypothetical protein, conserved 0.0364 0.1162 0.3692
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0075 0.0196 0.0626
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0128 0.0373
Schistosoma mansoni apoferritin-2 0.0028 0.0036 0.0036
Echinococcus granulosus GPCR family 2 0.0102 0.0285 0.0285
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0074 0.0074
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0178 0.0534
Schistosoma mansoni cytochrome B5 0.0108 0.0306 0.0306
Trypanosoma brucei heat shock protein, putative 0.007 0.0178 0.0534
Toxoplasma gondii heat shock protein 75, putative 0.0029 0.004 0.0187
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0431 0.1388 0.4436
Brugia malayi hypothetical protein 0.0164 0.0494 0.1547
Brugia malayi Steroid receptor seven-up type 2 0.0075 0.0196 0.0592
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0128 0.0373
Mycobacterium ulcerans oxygenase 0.0108 0.0306 0.0945
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.0286 0.2385
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0058 0.0185
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0085
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0144 0.0144
Brugia malayi photoreceptor-specific nuclear receptor 0.0075 0.0196 0.0592
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0042 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0075 0.0196 0.0592
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0162 0.0482
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0951 0.3129 1
Brugia malayi hypothetical protein 0.0039 0.0074 0.0202
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.004 0.0077 0.0077
Trichomonas vaginalis replication factor C large subunit, putative 0.0022 0.0016 0.0015
Echinococcus multilocularis heat shock protein 0.007 0.0178 0.0178
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0173 0.0173
Brugia malayi flavodoxin family protein 0.0364 0.1162 0.3692
Leishmania major oxidoreductase-like protein 0.0108 0.0306 0.0945
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0038 0.0085
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0201
Giardia lamblia Grp94/Hsp90 0.0056 0.013 0.0431
Loa Loa (eye worm) MH2 domain-containing protein 0.039 0.1251 0.3999
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0075 0.0196 0.0196
Echinococcus granulosus FTZ F1 alpha 0.0075 0.0196 0.0196
Giardia lamblia Heat shock protein HSP 90-alpha 0.007 0.0178 0.0604
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0075 0.0196 0.0196
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0951 0.3129 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0075 0.0196 0.0592
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0951 0.3129 0.3129
Onchocerca volvulus Huntingtin homolog 0.0533 0.1729 1
Trypanosoma brucei NADH-dependent fumarate reductase 0.0108 0.0306 0.0945
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0626
Echinococcus multilocularis protein dispatched 1 0.005 0.0111 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0992 0.3147
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0015 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0027 0.0051
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0108 0.0306 0.0945
Mycobacterium ulcerans glutaminase 0.0283 0.0893 0.2829
Schistosoma mansoni NADPH flavin oxidoreductase 0.0479 0.1548 0.1548
Leishmania major heat shock protein 83-1 0.007 0.0178 0.0534
Schistosoma mansoni lamin 0.0029 0.0042 0.0042

Activities

Activity type Activity value Assay description Source Reference
ED50 (ADMET) = 0.52 mg kg-1 Toxicity in sc dosed albino mouse assessed as mydriasis ChEMBL. 592326

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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