TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 341.408 | Formula: C18H23N5O2
H donors: 1 H acceptors: 3 LogP: 1.92 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: N#Cc1cccc(c1)OCCNC1CCCN(C1)Cc1noc(n1)C
InChi: 1S/C18H23N5O2/c1-14-21-18(22-25-14)13-23-8-3-5-16(12-23)20-7-9-24-17-6-2-4-15(10-17)11-19/h2,4,6,10,16,20H,3,5,7-9,12-13H2,1H3
InChiKey: LXFXCIHBMBOHDS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Toxoplasma gondii	ubiquitin-specific protease USP4	0.0005	0.003	0.0141
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0004	0.0006	0.0024
Toxoplasma gondii	hypothetical protein	0.001	0.0282	0.1311
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Entamoeba histolytica	Ras family GTPase	0.0035	0.1568	0.6306
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0042	0.1925	0.2523
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	small ubiquitin protein, putative	0.0041	0.1831	0.6212
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	N-terminal motif family protein	0.0007	0.0138	0.0138
Echinococcus multilocularis	protein quaking	0.0015	0.0549	0.0699
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0047	0.2155	0.873
Toxoplasma gondii	histone lysine acetyltransferase GCN5-A	0.0047	0.2155	1
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 47	0.0005	0.003	0.004
Schistosoma mansoni	kinase	0.0027	0.1153	0.1468
Schistosoma mansoni	ubiquitin-specific peptidase 10 (C19 family)	0.0005	0.003	0.0039
Echinococcus multilocularis	dna polymerase kappa	0.0045	0.2034	0.2589
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	Ubiquitin carboxyl terminal hydrolase 48	0.0005	0.003	0.004
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0005	0.003	0.004
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.0037	0.1648	0.1648
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Echinococcus granulosus	ATP dependent DNA helicase Q1	0.0006	0.006	0.0078
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Plasmodium vivax	flap endonuclease 1, putative	0.0015	0.0517	0.2397
Trichomonas vaginalis	flap endonuclease-1, putative	0.0015	0.0517	0.2093
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 24	0.0005	0.003	0.004
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0011	0.0357	0.0357
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	cyclin A, putative	0.0011	0.0357	0.1448
Loa Loa (eye worm)	hypothetical protein	0.0025	0.1046	0.1046
Giardia lamblia	Hypothetical protein	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	gcn5proteinral control of amino acid synthesis	0.016	0.7857	1
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase	0.0005	0.003	0.004
Mycobacterium ulcerans	hypothetical protein	0.0009	0.0246	0.1207
Trypanosoma brucei	DNA damage repair protein, putative	0.0009	0.0246	0.0834
Onchocerca volvulus		0.0005	0.003	0.003
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0005	0.003	0.0155
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 14	0.0005	0.003	0.0155
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0042	0.1925	0.7798
Plasmodium falciparum	ADP-dependent DNA helicase RecQ	0.0012	0.0376	0.1923
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	Protein son of sevenless	0.0007	0.0138	0.0181
Mycobacterium ulcerans	DNA polymerase IV	0.0045	0.2034	1
Mycobacterium leprae	Conserved hypothetical protein	0.0004	0	0.5
Schistosoma mansoni	hypothetical protein	0.0095	0.4576	0.5824
Echinococcus multilocularis	ATP dependent DNA helicase Q5	0.0006	0.006	0.0076
Toxoplasma gondii	hypothetical protein	0.0009	0.0218	0.1011
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Trichomonas vaginalis	rheb, putative	0.0035	0.1568	0.6352
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Toxoplasma gondii	protein kinase G AGC kinase family member PKG	0.0005	0.0024	0.011
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	0.0009	0.0227	0.1543
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Brugia malayi	RasGEF domain containing protein	0.0007	0.0138	0.0138
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Echinococcus granulosus	flap endonuclease 1	0.0015	0.0517	0.0677
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0042	0.1925	0.1925
Schistosoma mansoni	ubiquitin-specific peptidase 45 (C19 family)	0.0005	0.003	0.0039
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0009	0.0227	0.0288
Trypanosoma brucei	PAB1-binding protein , putative	0.0014	0.0493	0.1672
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	dishevelled	0.001	0.0282	0.0359
Trypanosoma cruzi	hypothetical protein	0.0007	0.0138	0.0468
Echinococcus multilocularis	expressed protein	0.0005	0.003	0.0039
Loa Loa (eye worm)	hypothetical protein	0.0042	0.1925	0.1925
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0042	0.1925	0.6531
Toxoplasma gondii	ATP-dependent DNA helicase, RecQ family protein	0.0006	0.006	0.0278
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0005	0.003	0.0039
Echinococcus multilocularis	cGMP dependent protein kinase 1	0.0005	0.0024	0.003
Brugia malayi	ubiquitin specific protease 14	0.0005	0.003	0.003
Brugia malayi	ubiquitin carboxyl-terminal hydrolase 46	0.0005	0.003	0.003
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	cyclin B, putative	0.0011	0.0357	0.1448
Schistosoma mansoni	ubiquitin-specific peptidase 4 (C19 family)	0.0005	0.003	0.0039
Trypanosoma cruzi	polo-like protein kinase, putative	0.0053	0.2468	0.8375
Loa Loa (eye worm)	tumor suppressor	0.018	0.8883	0.8883
Trypanosoma brucei	flap endonuclease-1 (FEN-1), putative	0.0015	0.0517	0.1753
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Echinococcus granulosus	cyclins	0.0011	0.0357	0.0468
Brugia malayi	serine/threonine-protein kinase plk-2	0.0053	0.2468	0.2468
Trichomonas vaginalis	cyclins, putative	0.0011	0.0357	0.1448
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Brugia malayi	Bloom's syndrome protein homolog	0.0013	0.0459	0.0459
Schistosoma mansoni	dep domain containing protein	0.001	0.0282	0.0359
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	ubiquitin specific protease 41	0.0042	0.1925	0.2523
Entamoeba histolytica	cyclin, putative	0.0011	0.0357	0.1341
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	hypothetical protein	0.0015	0.055	0.055
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Brugia malayi	regulator of G-protein signaling egl-10	0.001	0.0282	0.0282
Plasmodium vivax	ADP-dependent DNA helicase RecQ, putative	0.0009	0.0239	0.1109
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Toxoplasma gondii	UBA/TS-N domain-containing protein	0.0005	0.003	0.0141
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Schistosoma mansoni	z-protein (S1r protein)	0.001	0.0282	0.0359
Trichomonas vaginalis	GTP-binding protein rit, putative	0.0035	0.1568	0.6352
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0005	0.003	0.004
Echinococcus granulosus	cyclins	0.0011	0.0357	0.0468
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0053	0.2468	1
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0141
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0009	0.0227	0.0297
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0005	0.003	0.0155
Plasmodium falciparum	histone acetyltransferase GCN5	0.0043	0.1957	1
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Plasmodium falciparum	ataxin-2 like protein, putative	0.0014	0.0493	0.2519
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 47	0.0005	0.003	0.0039
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 14	0.0005	0.003	0.0039
Toxoplasma gondii	hypothetical protein	0.0005	0.003	0.0141
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	rap guanine nucleotide exchange factor 6	0.0007	0.0138	0.0181
Trypanosoma brucei	unspecified product	0.0041	0.1848	0.6269
Loa Loa (eye worm)	RasGEF domain-containing protein	0.0007	0.0138	0.0138
Brugia malayi	Flap endonuclease-1	0.0015	0.0517	0.0517
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.0037	0.1648	0.1648
Trypanosoma cruzi	polo-like protein kinase, putative	0.0053	0.2468	0.8375
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0493	0.0493
Mycobacterium tuberculosis	Conserved hypothetical protein	0.003	0.1282	0.8728
Leishmania major	ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 22	0.0005	0.003	0.0039
Toxoplasma gondii	flap structure-specific endonuclease 1, putative	0.0015	0.0517	0.2397
Trichomonas vaginalis	cyclin B, putative	0.0011	0.0357	0.1448
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Ras-related protein R-Ras2	0.0035	0.1568	0.1568
Echinococcus granulosus	G2:mitotic specific cyclin B3	0.0011	0.0357	0.0468
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0042	0.1925	0.6531
Toxoplasma gondii	ubiquitin specific protease 39 isoform 2, putative	0.0005	0.003	0.0141
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.0037	0.1648	0.2098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	ras GTP exchange factor, putative	0.0007	0.0138	0.0559
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	ubiquitin-specific peptidase 42 (C19 family)	0.0005	0.003	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Loa Loa (eye worm)	flap endonuclease-1	0.0015	0.0517	0.0517
Trypanosoma brucei	DNA polymerase kappa, putative	0.0024	0.0998	0.3388
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0042	0.1925	0.6531
Onchocerca volvulus		0.0005	0.003	0.003
Echinococcus granulosus	son of sevenless 1	0.0007	0.0138	0.0181
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0063	0.2947	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0007	0.0138	0.0138
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 14	0.0005	0.003	0.004
Trypanosoma brucei	isocitrate dehydrogenase, putative	0.0009	0.0227	0.0769
Trypanosoma brucei	DNA polymerase kappa, putative	0.0024	0.1002	0.3401
Echinococcus granulosus	transcription factor Dp 1	0.0021	0.0861	0.1128
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Schistosoma mansoni	guanine-nucleotide-exchange-factor	0.0007	0.0138	0.0176
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	cyclins	0.0011	0.0357	0.0455
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Plasmodium falciparum	ubiquitin specific protease, putative	0.0005	0.003	0.0155
Trypanosoma brucei	DNA polymerase kappa, putative	0.0024	0.0998	0.3388
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0005	0.003	0.0039
Trypanosoma brucei	calpain-like protein, putative	0.0063	0.2947	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	DNA damage repair protein, putative	0.0009	0.0246	0.0834
Onchocerca volvulus		0.0025	0.1046	0.1046
Trypanosoma brucei	unspecified product	0.002	0.0815	0.2767
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Echinococcus granulosus	cGMP dependent protein kinase	0.0005	0.0024	0.0031
Trichomonas vaginalis	conserved hypothetical protein	0.0011	0.0357	0.1448
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0009	0.0227	0.0288
Plasmodium vivax	ataxin-2 like protein, putative	0.0014	0.0493	0.2288
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0042	0.1925	0.245
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0141
Schistosoma mansoni	cyclin B	0.0011	0.0357	0.0455
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase family 2 protein	0.0005	0.003	0.0141
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Trichomonas vaginalis	rap1 and, putative	0.0035	0.1568	0.6352
Echinococcus granulosus	regulator of G protein signaling 7	0.001	0.0282	0.037
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	DNA damage repair protein, putative	0.0009	0.0246	0.0834
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Giardia lamblia	Hypothetical protein	0.0011	0.0357	0.1448
Toxoplasma gondii	ATP-dependent DNA helicase, RecQ family protein	0.0006	0.006	0.0278
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus granulosus	rap guanine nucleotide exchange factor 1	0.0007	0.0138	0.0181
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	protein quaking	0.0015	0.0549	0.072
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0009	0.0227	0.0288
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.003	0.1282	0.1631
Plasmodium falciparum	ATP-dependent DNA helicase Q1	0.0006	0.006	0.0306
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Trypanosoma brucei	unspecified product	0.002	0.0815	0.2767
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Echinococcus granulosus	cyclins	0.0011	0.0357	0.0468
Schistosoma mansoni	ras GTP exchange factor son of sevenless	0.0007	0.0138	0.0176
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0042	0.1925	0.2523
Trypanosoma brucei	small ubiquitin-related modifier	0.0041	0.1831	0.6212
Echinococcus granulosus	bloom syndrome protein	0.0013	0.0459	0.0601
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.0037	0.1648	0.6635
Schistosoma mansoni	hypothetical protein	0.0005	0.003	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0011	0.0357	0.0357
Plasmodium vivax	histone acetyltransferase GCN5, putative	0.0047	0.2155	1
Schistosoma mansoni	serine/threonine protein kinase	0.0053	0.2468	0.3142
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Plasmodium vivax	small ubiquitin-related modifier, putative	0.0041	0.1831	0.8496
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0005	0.003	0.004
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.001	0.0282	0.0282
Trichomonas vaginalis	cat eye syndrome critical region protein 2, cscr2, putative	0.0047	0.2155	0.873
Trichomonas vaginalis	cyclin D, putative	0.0011	0.0357	0.1448
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Brugia malayi	ImpB/MucB/SamB family protein	0.0044	0.2003	0.2003
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	segment polarity protein dishevelled	0.001	0.0282	0.0359
Echinococcus multilocularis	Pleckstrin G protein, interacting region	0.001	0.0282	0.0359
Echinococcus granulosus	segment polarity protein dishevelled	0.001	0.0282	0.037
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	ATP-dependent DEAD/H DNA helicase recQ, putative	0.0007	0.0142	0.0483
Trichomonas vaginalis	guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0559
Trichomonas vaginalis	conserved hypothetical protein	0.0042	0.1925	0.7798
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	ATP dependent DNA helicase Q1	0.0006	0.006	0.0076
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Brugia malayi	Domain found in Dishevelled, Egl-10, and Pleckstrin family protein	0.001	0.0282	0.0282
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Trichomonas vaginalis	ras GTP exchange factor, son of sevenless, putative	0.0007	0.0138	0.0559
Trypanosoma brucei	chrX additional, unordered contigs	0.0009	0.0246	0.0834
Echinococcus granulosus	5'partial\|Ubiquitin carboxyl terminal hydrolase 48	0.0005	0.003	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	ubiquitin-specific peptidase 46 (C19 family)	0.0005	0.003	0.0039
Echinococcus multilocularis	son of sevenless 1	0.0007	0.0138	0.0176
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0063	0.2947	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Trypanosoma brucei	DNA polymerase kappa, putative	0.0033	0.1468	0.4983
Trypanosoma cruzi	cyclin, putative	0.0011	0.0357	0.1213
Echinococcus granulosus	ubiquitin	0.0025	0.1046	0.1371
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus granulosus	u4:u6.u5 tri snrnp associated protein 2	0.0005	0.003	0.004
Schistosoma mansoni	ubiquitin-specific peptidase 14 (C19 family)	0.0005	0.003	0.0039
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0037	0.1648	0.5592
Brugia malayi	RasGEF domain containing protein	0.0007	0.0138	0.0138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	isocitrate dehydrogenase	0.0009	0.0227	0.0227
Loa Loa (eye worm)	hypothetical protein	0.0006	0.006	0.006
Echinococcus granulosus	hypothetical protein	0.0015	0.0549	0.072
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0042	0.1925	0.6531
Toxoplasma gondii	isocitrate dehydrogenase	0.0009	0.0227	0.1052
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase 46	0.0005	0.003	0.003
Echinococcus granulosus	Small ubiquitin modifier 2	0.0041	0.1831	0.2399
Trypanosoma cruzi	hypothetical protein	0.0007	0.0138	0.0468
Leishmania major	CYC2-like cyclin, putative,cyclin 6, putative	0.0011	0.0357	0.1213
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0998	0.0998
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Giardia lamblia	DNA damage repair protein	0.0009	0.0246	0.0995
Giardia lamblia	Flap structure-specific endonuclease	0.0015	0.0517	0.2093
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0005	0.003	0.0123
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.003	0.1282	0.168
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Schistosoma mansoni	terminal deoxycytidyl transferase	0.003	0.1282	0.1631
Trypanosoma brucei	hypothetical protein	0.0063	0.2947	1
Brugia malayi	ATP-dependent DNA helicase, RecQ family protein	0.0006	0.006	0.006
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Loa Loa (eye worm)	DIX domain-containing protein	0.001	0.0282	0.0282
Trichomonas vaginalis	cyclins, putative	0.0011	0.0357	0.1448
Brugia malayi	Isocitrate dehydrogenase	0.0009	0.0227	0.0227
Brugia malayi	Temporarily assigned gene name protein 44	0.0015	0.055	0.055
Giardia lamblia	Sgs1 DNA helicase, putative	0.0006	0.006	0.0243
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Echinococcus multilocularis	flap endonuclease 1	0.0015	0.0517	0.0657
Entamoeba histolytica	Ras family GTPase	0.0035	0.1568	0.6306
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	expressed conserved protein	0.0005	0.0024	0.003
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0042	0.1925	0.7798
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	flap endonuclease-1 (FEN-1), putative	0.0015	0.0517	0.1753
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	cyclin B	0.0011	0.0357	0.0455
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0005	0.003	0.004
Giardia lamblia	DUB-1	0.0005	0.003	0.0123
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus granulosus	Pleckstrin G protein interacting region	0.001	0.0282	0.037
Plasmodium falciparum	ubiquitin specific protease, putative	0.0005	0.003	0.0155
Treponema pallidum	cyclic nucleotide binding protein	0.0004	0	0.5
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0053	0.2468	0.3142
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0009	0.0227	0.0288
Treponema pallidum	catabolite gene activator	0.0004	0	0.5
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Onchocerca volvulus		0.001	0.0282	0.0282
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0005	0.003	0.0141
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0033	0.1468	0.4983
Brugia malayi	polk-prov protein	0.0024	0.0998	0.0998
Onchocerca volvulus		0.0011	0.0357	0.0357
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.0009	0.0227	0.1052
Echinococcus granulosus	ATP dependent DNA helicase Q5	0.0006	0.006	0.0078
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Schistosoma mansoni	ubiquitin-specific peptidase 44 (C19 family)	0.0005	0.003	0.0039
Schistosoma mansoni	serine/threonine protein kinase	0.0005	0.0024	0.003
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Toxoplasma gondii	BRCA1 C Terminus (BRCT) domain-containing protein	0.0013	0.0432	0.2007
Leishmania major	DNA polymerase kappa, putative	0.0009	0.0246	0.0834
Onchocerca volvulus		0.0007	0.0138	0.0138
Loa Loa (eye worm)	hypothetical protein	0.001	0.0282	0.0282
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 24	0.0005	0.003	0.0039
Echinococcus multilocularis	geminin	0.0095	0.4576	0.5824
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.0037	0.1648	0.5592
Brugia malayi	hypothetical protein	0.0009	0.024	0.024
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0009	0.0227	0.0288
Onchocerca volvulus		0.0005	0.003	0.003
Schistosoma mansoni	ras GTP exchange factor son of sevenless	0.0007	0.0138	0.0176
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	cyclin 6, putative	0.0011	0.0357	0.1213
Giardia lamblia	DINP protein human, muc B family	0.0033	0.1468	0.5949
Schistosoma mansoni	serine/threonine protein kinase	0.0005	0.0024	0.003
Plasmodium vivax	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0005	0.003	0.0141
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	calpain-7 (C02 family)	0.0005	0.003	0.0039
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Brugia malayi	RasGEF domain containing protein	0.0007	0.0138	0.0138
Echinococcus granulosus	cyclin b3	0.0011	0.0357	0.0468
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0033	0.1468	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0047	0.2155	0.2824
Schistosoma mansoni	dishevelled	0.001	0.0282	0.0359
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Trichomonas vaginalis	ras-dva small GTPase, putative	0.0035	0.1568	0.6352
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Leishmania major	protein kinase, putative	0.0005	0.0024	0.008
Trichomonas vaginalis	ral, putative	0.0035	0.1568	0.6352
Giardia lamblia	Cyclin A	0.0011	0.0357	0.1448
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 1, putative	0.0005	0.003	0.0141
Trypanosoma cruzi	PAB1-binding protein , putative	0.0014	0.0493	0.1672
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	DNA polymerase IV / kappa	0.0009	0.0246	0.0313
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	G2:mitotic specific cyclin B3	0.0011	0.0357	0.0455
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.003	0.1282	0.1282
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Trypanosoma brucei	mitotic cyclin 6	0.0011	0.0357	0.1213
Schistosoma mansoni	DNA polymerase eta	0.0044	0.2003	0.2549
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0005	0.003	0.0039
Loa Loa (eye worm)	hypothetical protein	0.0035	0.1568	0.1568
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.003
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Brugia malayi	hypothetical protein	0.0005	0.003	0.003
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0045	0.2034	0.8242
Trypanosoma brucei	calpain, putative	0.0063	0.2947	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	peptidase	0.0005	0.0054	0.0069
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0011	0.0357	0.0357
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0063	0.2947	1
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0005	0.003	0.0123
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Echinococcus granulosus	cyclins	0.0011	0.0357	0.0468
Chlamydia trachomatis	cAMP-dependent protein kinase regulatory subunit	0.0004	0	0.5
Plasmodium falciparum	small ubiquitin-related modifier	0.0041	0.1831	0.9355
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Entamoeba histolytica	cyclin family protein	0.0011	0.0357	0.1341
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.0009	0.0227	0.1158
Trypanosoma cruzi	CYC2-like cyclin, putative	0.0011	0.0357	0.1213
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Toxoplasma gondii	isocitrate dehydrogenase	0.0009	0.0227	0.1052
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0007	0.0138	0.0138
Echinococcus multilocularis	Small ubiquitin modifier 2	0.0041	0.1831	0.233
Echinococcus multilocularis	ubiquitin specific peptidase 42 (C19 family)	0.0005	0.003	0.0039
Echinococcus multilocularis	ubiquitin specific protease 41	0.0042	0.1925	0.245
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Schistosoma mansoni	DNA helicase recq5	0.0006	0.006	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0007	0.0138	0.0138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	polo-like protein kinase	0.0053	0.2468	0.8375
Loa Loa (eye worm)	hypothetical protein	0.0202	1	1
Echinococcus granulosus	cyclin B	0.0011	0.0357	0.0468
Trichomonas vaginalis	cyclin D, putative	0.0011	0.0357	0.1448
Schistosoma mansoni	ras GTP exchange factor	0.0007	0.0138	0.0176
Leishmania major	protein kinase, putative	0.0005	0.0024	0.008
Brugia malayi	hypothetical protein	0.001	0.0282	0.0282
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 22	0.0005	0.003	0.004
Trypanosoma brucei	DNA polymerase kappa, putative	0.0024	0.1002	0.3401
Trypanosoma brucei	DNA damage repair protein, putative	0.0009	0.0246	0.0834
Trichomonas vaginalis	DNA helicase recq, putative	0.0013	0.0459	0.1859
Loa Loa (eye worm)	hypothetical protein	0.0068	0.32	0.32
Trypanosoma cruzi	cyclin, putative	0.0011	0.0357	0.1213
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	camp-dependent rap1 guanine-nucleotide exchange factor	0.0007	0.012	0.0153
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 36	0.0005	0.003	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	hypothetical protein, conserved	0.0014	0.0493	0.1672
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Schistosoma mansoni	DNA helicase recq1	0.0006	0.006	0.0076
Trypanosoma brucei	hypothetical protein, conserved	0.0009	0.0246	0.0834
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Giardia lamblia	Histone acetyltransferase GCN5	0.0043	0.1957	0.7928
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0042	0.1925	0.245
Giardia lamblia	Sentrin	0.0041	0.1831	0.7417
Schistosoma mansoni	ubiquitin-like protein sumo/smt3-related	0.0041	0.1831	0.233
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 12	0.0005	0.003	0.0039
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 23	0.0005	0.003	0.004
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Entamoeba histolytica	Flap nuclease, putative	0.0015	0.0517	0.1994
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	bloom syndrome protein	0.0013	0.0459	0.0584
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Echinococcus multilocularis	Ubiquitin carboxyl terminal hydrolase 48	0.0005	0.003	0.0039
Trichomonas vaginalis	cyclins, putative	0.0011	0.0357	0.1448
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 16	0.0005	0.003	0.0039
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 20	0.0005	0.003	0.0039
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0005	0.003	0.004
Plasmodium falciparum	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0005	0.003	0.0155
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trypanosoma brucei	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0009	0.0227	0.0769
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 5	0.0005	0.003	0.004
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0009	0.0227	0.0769
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0357	0.0357
Trichomonas vaginalis	cyclin B, putative	0.0011	0.0357	0.1448
Echinococcus multilocularis	rap guanine nucleotide exchange factor 1	0.0007	0.0138	0.0176
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0005	0.003	0.0141
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Echinococcus multilocularis	Protein son of sevenless	0.0007	0.0138	0.0176
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	hypothetical protein	0.0015	0.0549	0.0699
Loa Loa (eye worm)	cyclin domain-containing protein	0.0011	0.0357	0.0357
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	cyclin B, putative	0.0011	0.0357	0.1448
Loa Loa (eye worm)	AGC/PKG protein kinase	0.0005	0.0024	0.0024
Trypanosoma cruzi	PAB1-binding protein , putative	0.0014	0.0493	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0005	0.0024	0.0031
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0037	0.1648	0.5592
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0005	0.003	0.0123
Schistosoma mansoni	family C19 non-peptidase homologue (C19 family)	0.0005	0.003	0.0039
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Brugia malayi	DIX domain containing protein	0.001	0.0282	0.0282
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Plasmodium falciparum	cGMP-dependent protein kinase	0.0005	0.0024	0.0121
Plasmodium vivax	hypothetical protein, conserved	0.0005	0.003	0.0141
Brugia malayi	acetyltransferase, GNAT family protein	0.016	0.7857	0.7857
Treponema pallidum	cyclic nucleotide binding protein	0.0004	0	0.5
Brugia malayi	hypothetical protein	0.0014	0.0493	0.0493
Schistosoma mansoni	ubiquitin-specific peptidase 48 (C19 family)	0.0005	0.003	0.0039
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0009	0.0227	0.0769
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Schistosoma mansoni	ubiquitin-specific peptidase 30 (C19 family)	0.0005	0.003	0.0039
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trypanosoma brucei	DNA polymerase IV, putative	0.0045	0.2034	0.6903
Echinococcus multilocularis	transcription factor Dp 1	0.0021	0.0861	0.1096
Leishmania major	ATP-dependent DEAD/H DNA helicase recQ, putative	0.0007	0.0142	0.0483
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0005	0.0024	0.0031
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0005	0.003	0.0123
Loa Loa (eye worm)	RasGEF domain-containing protein	0.0007	0.0138	0.0138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0005	0.003	0.0039
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0202	1	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Domain found in Dishevelled, Egl-10, and Pleckstrin family protein	0.001	0.0282	0.0282
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Echinococcus granulosus	ras gtpase	0.0035	0.1568	0.2055
Echinococcus multilocularis	rap guanine nucleotide exchange factor 6	0.0007	0.0138	0.0176
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	DNA helicase recq1, putative	0.0013	0.0459	0.1859
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0005	0.003	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0063	0.2947	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Loa Loa (eye worm)	SMO-1 protein	0.0041	0.1831	0.1831
Trichomonas vaginalis	cyclin B, putative	0.0011	0.0357	0.1448
Echinococcus granulosus	cyclins	0.0011	0.0357	0.0468
Trichomonas vaginalis	ubiquitin, putative	0.0025	0.1046	0.4238
Echinococcus granulosus	dna polymerase kappa	0.0045	0.2034	0.2666
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0042	0.1925	0.7798
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0005	0.003	0.0039
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0155	0.763	1
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.0063	0.2947	1
Trypanosoma cruzi	DNA polymerase eta, putative	0.0044	0.2003	0.6796
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Plasmodium falciparum	DNA repair protein REV1, putative	0.0009	0.0246	0.1255
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0042	0.1925	0.245
Giardia lamblia	Kinase, PLK	0.0053	0.2468	1
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.0037	0.1648	0.2098
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0.0138	0.0441
Echinococcus multilocularis	cyclin b3	0.0011	0.0357	0.0455
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0053	0.2468	0.8375
Toxoplasma gondii	LsmAD domain-containing protein	0.0014	0.0493	0.2288
Echinococcus multilocularis	regulator of G protein signaling 7	0.001	0.0282	0.0359
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0357	0.0357
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Trypanosoma cruzi	DNA polymerase eta, putative	0.0023	0.0967	0.328
Schistosoma mansoni	ubiquitin-specific peptidase 7 (C19 family)	0.0005	0.003	0.0039
Toxoplasma gondii	small ubiquitin family modifier, putative	0.0041	0.1831	0.8496
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Brugia malayi	Ubiquitin-like protein SMT3	0.0041	0.1831	0.1831
Trypanosoma brucei	cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Trypanosoma brucei	DNA polymerase kappa, putative	0.0024	0.1002	0.3401
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0009	0.0246	0.114
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	CAMK family protein kinase	0.0026	0.1118	0.453
Echinococcus multilocularis	cyclins	0.0011	0.0357	0.0455
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0005	0.003	0.0123
Schistosoma mansoni	cyclin B3	0.0011	0.0357	0.0455
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Plasmodium falciparum	ataxin-2 like protein, putative	0.0014	0.0493	0.2519
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	segment polarity protein dishevelled	0.001	0.0282	0.037
Leishmania major	DNA polymerase kappa, putative	0.0033	0.1468	0.4983
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0053	0.2468	0.2468
Trichomonas vaginalis	cyclin B3, putative	0.0011	0.0357	0.1448
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	cyclin	0.0011	0.0357	0.1213
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Leishmania major	DNA polymerase eta, putative	0.0023	0.0967	0.328
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0005	0.003	0.0039
Entamoeba histolytica	deoxycytidyl transferase, putative	0.003	0.1282	0.5133
Loa Loa (eye worm)	hypothetical protein	0.001	0.0282	0.0282
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0023	0.0967	0.4487
Echinococcus multilocularis	ubiquitin	0.0025	0.1046	0.1331
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Loa Loa (eye worm)	hypothetical protein	0.0044	0.2003	0.2003
Plasmodium vivax	ubiquitin specific protease, putative	0.0005	0.003	0.0141
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0042	0.1925	0.245
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Giardia lamblia	G2/mitotic-specific cyclin B	0.0011	0.0357	0.1448
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Loa Loa (eye worm)	hypothetical protein	0.001	0.0282	0.0282
Trypanosoma cruzi	small ubiquitin protein, putative	0.0041	0.1831	0.6212
Schistosoma mansoni	family C19 unassigned peptidase (C19 family)	0.0005	0.003	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0037	0.1648	0.5592
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Echinococcus granulosus	regulator of G protein signaling 7	0.001	0.0282	0.037
Schistosoma mansoni	ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold	0.0005	0.003	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Onchocerca volvulus	Segment polarity protein dishevelled homolog	0.001	0.0282	0.0282
Trypanosoma brucei	DNA polymerase eta, putative	0.0044	0.2003	0.6796
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0063	0.2947	1
Schistosoma mansoni	hypothetical protein	0.0095	0.4576	0.5824
Plasmodium vivax	DNA repair protein REV1, putative	0.0009	0.0246	0.114
Plasmodium falciparum	cyclin	0.0011	0.0357	0.1826
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0009	0.0227	0.0227
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	DNA polymerase IV, putative	0.0045	0.2034	0.6903
Entamoeba histolytica	ubiquitin like protein	0.0041	0.1831	0.7385
Entamoeba histolytica	cyclin family protein	0.0011	0.0357	0.1341
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Schistosoma mansoni	regulator of G protein signaling	0.001	0.0282	0.0359
Echinococcus granulosus	ubiquitin specific peptidase 30 (C19 family)	0.0005	0.003	0.004
Entamoeba histolytica	ras-1, putative	0.0035	0.1568	0.6306
Leishmania major	DNA polymerase eta, putative	0.0044	0.2003	0.6796
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0006	0.0099	0.0127
Entamoeba histolytica	hypothetical protein	0.0025	0.1046	0.4166
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Echinococcus granulosus	dna polymerase eta	0.0044	0.2003	0.2625
Trichomonas vaginalis	CAMK family protein kinase	0.0053	0.2468	1
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0005	0.003	0.0123
Trypanosoma cruzi	small ubiquitin protein, putative	0.0041	0.1831	0.6212
Echinococcus multilocularis	ras GTP exchange factor	0.0007	0.0138	0.0176
Leishmania major	flap endonuclease-1 (FEN-1), putative	0.0015	0.0517	0.1753
Schistosoma mansoni	fyve finger-containing phosphoinositide kinase fyv1	0.001	0.0282	0.0359
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Loa Loa (eye worm)	Ras protein let-60	0.0035	0.1568	0.1568
Toxoplasma gondii	histone lysine acetyltransferase GCN5-B	0.0047	0.2155	1
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	CAMK family protein kinase	0.0026	0.1118	0.453
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Trypanosoma cruzi	DNA damage repair protein, putative	0.0009	0.0246	0.0834
Brugia malayi	N-terminal motif family protein	0.0007	0.0138	0.0138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 12	0.0005	0.003	0.004
Echinococcus multilocularis	u4:u6.u5 tri snrnp associated protein 2	0.0005	0.003	0.0039
Trichomonas vaginalis	DNA helicase recq, putative	0.0007	0.0142	0.0577
Echinococcus multilocularis	cGMP dependent protein kinase 1	0.0005	0.0024	0.003
Trichomonas vaginalis	conserved hypothetical protein	0.0025	0.1046	0.4238
Brugia malayi	ImpB/MucB/SamB family protein	0.003	0.1282	0.1282
Brugia malayi	hypothetical protein	0.001	0.0282	0.0282
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0006	0.0099	0.013
Echinococcus multilocularis	dna polymerase eta	0.0044	0.2003	0.2549
Schistosoma mansoni	gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2	0.016	0.7857	1
Entamoeba histolytica	cyclin, putative	0.0011	0.0357	0.1341
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Schistosoma mansoni	ubiquitin-specific peptidase 5 (C19 family)	0.0005	0.003	0.0039
Trypanosoma brucei	ATP-dependent DEAD/H DNA helicase recQ, putative	0.0007	0.0142	0.0483
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	cyclin B3 1	0.0011	0.0357	0.0455
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Loa Loa (eye worm)	RasGEF domain-containing protein	0.0007	0.0138	0.0138
Echinococcus multilocularis	ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase	0.0005	0.003	0.0039
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0005	0.003	0.0141
Treponema pallidum	catabolite gene activator (Crp)	0.0004	0	0.5
Schistosoma mansoni	ubiquitin-specific peptidase 22 (C19 family)	0.0005	0.003	0.0039
Trichomonas vaginalis	dexras1, putative	0.0035	0.1568	0.6352
Echinococcus granulosus	geminin	0.0095	0.4576	0.5997
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0155
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 20	0.0005	0.003	0.004
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Brugia malayi	hypothetical protein	0.0025	0.1046	0.1046
Trypanosoma brucei	variant surface glycoprotein (VSG), putative	0.0063	0.2947	1
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Mycobacterium ulcerans	DNA polymerase IV	0.0045	0.2034	1
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.1831	0.7417
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Trichomonas vaginalis	cyclins, putative	0.0011	0.0357	0.1448
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0042	0.1925	0.7771
Echinococcus multilocularis	segment polarity protein dishevelled	0.001	0.0282	0.0359
Trichomonas vaginalis	ras GTP exchange factor, putative	0.0007	0.0138	0.0559
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Brugia malayi	Egg laying defective protein 4	0.0005	0.0024	0.0024
Trypanosoma cruzi	hypothetical protein, conserved	0.0009	0.0246	0.0834
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase	0.0005	0.003	0.0039
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Echinococcus multilocularis	regulator of G protein signaling 7	0.001	0.0282	0.0359
Trypanosoma cruzi	hypothetical protein, conserved	0.0009	0.0246	0.0834
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 36	0.0005	0.003	0.0039
Echinococcus multilocularis	isocitrate dehydrogenase	0.0009	0.0227	0.0288
Brugia malayi	tumor suppressor.	0.018	0.8883	0.8883
Schistosoma mansoni	flap endonuclease-1	0.0013	0.0446	0.0567
Loa Loa (eye worm)	ubiquitin specific peptidase 39	0.0005	0.003	0.003
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Loa Loa (eye worm)	acetyltransferase	0.016	0.7857	0.7857
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.0037	0.1648	0.216
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase family 2, putative	0.0005	0.003	0.0141
Brugia malayi	ATP-dependent DNA helicase, RecQ family protein	0.0006	0.006	0.006
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Schistosoma mansoni	ubiquitin-specific peptidase 24 (C19 family)	0.0005	0.003	0.0039
Trichomonas vaginalis	conserved hypothetical protein	0.0005	0.003	0.0123
Trichomonas vaginalis	DNA polymerase eta, putative	0.0045	0.2034	0.8242
Toxoplasma gondii	ATP-dependent DNA helicase, RecQ family protein	0.0009	0.0233	0.1083
Trypanosoma brucei	DNA polymerase IV, putative	0.0041	0.1848	0.6269
Trypanosoma cruzi	isocitrate dehydrogenase, putative	0.0009	0.0227	0.0769
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 16	0.0005	0.003	0.004
Echinococcus granulosus	ras GTP exchange factor	0.0007	0.0138	0.0181
Echinococcus granulosus	ubiquitin specific peptidase c family	0.0005	0.003	0.004
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0053	0.2468	0.3235
Loa Loa (eye worm)	ATP-dependent DNA helicase	0.0006	0.006	0.006
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0155
Schistosoma mansoni	ubiquitin-specific peptidase 16 (C19 family)	0.0005	0.003	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0005	0.003	0.0103
Schistosoma mansoni	hypothetical protein	0.0006	0.0099	0.0127
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	calpain-7 (C02 family)	0.0005	0.003	0.0039
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0053	0.2468	0.2468
Entamoeba histolytica	hypothetical protein	0.0007	0.0138	0.0441
Echinococcus granulosus	cyclin B3 1	0.0011	0.0357	0.0468
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Schistosoma mansoni	hypothetical protein	0.0015	0.0549	0.0699
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.003	0.1282	0.1631
Entamoeba histolytica	recQ family helicase, putative	0.0007	0.0142	0.046
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Schistosoma mansoni	ras GTP exchange factor son of sevenless	0.0007	0.0138	0.0176
Entamoeba histolytica	acetyltransferase, GNAT family	0.0043	0.1957	0.7902
Loa Loa (eye worm)	RecQ helicase	0.0013	0.0459	0.0459
Echinococcus multilocularis	ras gtpase	0.0035	0.1568	0.1995
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0004	0.0006	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0015	0.055	0.055
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma brucei	hypothetical protein, conserved	0.0009	0.0246	0.0834
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0063	0.2947	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Loa Loa (eye worm)	hypothetical protein	0.0005	0.003	0.003
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Plasmodium falciparum	flap endonuclease 1	0.0015	0.0517	0.264
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0005	0.003	0.0103
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	serine/threonine protein kinase	0.0005	0.0024	0.003
Brugia malayi	Ras protein let-60	0.0035	0.1568	0.1568
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 5	0.0005	0.003	0.0039
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0005	0.003	0.003
Trypanosoma cruzi	guanine nucleotide releasing protein, putative	0.0007	0.0138	0.0468
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0005	0.003	0.0123
Schistosoma mansoni	blooms syndrome DNA helicase	0.0011	0.0316	0.0402
Trichomonas vaginalis	cyclins, putative	0.0011	0.0357	0.1448
Trypanosoma brucei	DNA polymerase kappa, putative	0.0045	0.2034	0.6903
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0005	0.003	0.0123
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0063	0.2947	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL3490873

Bibliographic References

No literature references available for this target.

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Detailed information for compound 2070120