Detailed information for compound 2113448

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 484.294 | Formula: C28H40N2O5
  • H donors: 1 H acceptors: 4 LogP: 5.39 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(c1ccc(n1CC)C(=O)N(CC(=O)O)C)(c1ccc(c(c1)C)OCC(=O)C(C)(C)C)CC
  • InChi: InChI=1S/C28H40N2O5/c1-9-28(10-2,20-12-14-22(19(4)16-20)35-18-24(31)27(5,6)7)23-15-13-21(30(23)11-3)26(34)29(8)17-25(32)33/h12-16H,9-11,17-18H2,1-8H3,(H,32,33)
  • InChiKey: VGRFYHMXBZGNBO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei glycerolphosphate mutase, putative 0.007 0.013 0.0123
Plasmodium vivax hypothetical protein, conserved 0.008 0.0155 0.804
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0069 0.0069
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0043 0.169
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0014 0.012
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0004 0.0038
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0046 0.0406
Echinococcus multilocularis musashi 0.0053 0.0089 0.0089
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.007 0.013 0.013
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.007 0.013 0.013
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0043 0.0429
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0155 0.1356
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0043 0.0429
Onchocerca volvulus Protein UBASH3A homolog 0.007 0.013 0.0116
Onchocerca volvulus 0.0093 0.0185 0.0171
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.4154 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0089 0.074
Echinococcus multilocularis zinc phosphodiesterase 0.0095 0.0189 0.0189
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0116
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0046 0.0046
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0115 0.0115
Trypanosoma brucei phosphoglycerate mutase, putative 0.007 0.013 0.0123
Toxoplasma gondii phosphoglycerate mutase PGMII 0.007 0.013 0.6612
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.013
Brugia malayi hypothetical protein 0.0018 0.0004 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0035 0.0308
Plasmodium falciparum choline kinase 0.0041 0.006 0.2631
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0126 0.0126
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0189 0.1657
Echinococcus multilocularis lamin dm0 0.0053 0.0089 0.0089
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0072 0.0072
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0028 0.0833
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.0544 0.0544
Schistosoma mansoni ferritin 0.0016 0.0000080918 0.0000080918
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0076 0.0143 0.1186
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.007 0.013 0.0116
Toxoplasma gondii phosphoglycerate mutase 0.007 0.013 0.6612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.018
Giardia lamblia GTOR 0.0046 0.0072 0.0075
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.0095 0.0189 1
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.4084 0.9831 0.983
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0043 0.0043
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0095 0.0189 0.0189
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0014 0.0114
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0076 0.0076
Schistosoma mansoni ferritin 0.0016 0.0000080918 0.0000080918
Chlamydia trachomatis ribonuclease Z 0.0095 0.0189 1
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.0544 0.0544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.018
Brugia malayi Pre-SET motif family protein 0.0429 0.0998 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0047 0.0047
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0028 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0573 0.5023
Loa Loa (eye worm) phosphoglycerate mutase 0.007 0.013 0.013
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0046 0.0046
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.008 0.0155 0.1286
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0116
Loa Loa (eye worm) RNA binding protein 0.0064 0.0115 0.0115
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0069 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0043 0.0043
Echinococcus granulosus alkaline phosphatase 0.016 0.0347 0.0347
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0058 0.0506
Onchocerca volvulus Putative hydrolase PNKD 0.0095 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.013
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0072 0.0099
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.0001
Schistosoma mansoni ferritin 0.0016 0.0000080918 0.0000080918
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0076 0.0143 0.1186
Echinococcus granulosus lamin 0.0053 0.0089 0.0089
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0088 0.0881
Echinococcus granulosus intermediate filament protein 0.0053 0.0089 0.0089
Echinococcus multilocularis ferritin 0.0016 0.0000080918 0.0000080918
Plasmodium vivax choline kinase, putative 0.0041 0.006 0.2631
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.4084 0.9831 0.983
Trichomonas vaginalis esterase, putative 0.008 0.0155 0.1356
Onchocerca volvulus Protein UBASH3A homolog 0.007 0.013 0.0116
Schistosoma mansoni hypothetical protein 0.007 0.013 0.013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Mycobacterium ulcerans lipoprotein LpqD 0.007 0.013 0.022
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.007 0.013 0.1078
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0058 0.0044
Onchocerca volvulus 0.0053 0.0089 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.0179
Trypanosoma brucei glyoxalase II 0.0095 0.0189 0.0183
Schistosoma mansoni alpha glucosidase 0.0036 0.0046 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0076 0.0143 0.0242
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0076 0.0143 0.0242
Echinococcus granulosus cpg binding protein 0.0033 0.004 0.004
Plasmodium vivax SET domain protein, putative 0.0062 0.011 0.5512
Echinococcus multilocularis geminin 0.0719 0.1697 0.1697
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0058 0.0051
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0123 0.0257 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.018
Mycobacterium leprae conserved hypothetical protein 0.0095 0.0189 1
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0123
Giardia lamblia Hypothetical protein 0.2452 0.5885 1
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0155 0.0141
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.007 0.013 0.0116
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0155 0.0148
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.0095 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.0053 0.0088 0.0088
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0014 0.0114
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0076 0.0143 0.0242
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.011 0.011
Echinococcus multilocularis tumor protein p63 0.0326 0.0749 0.0749
Trichomonas vaginalis conserved hypothetical protein 0.007 0.013 0.1136
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0001 0.0006
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.0095 0.0189 0.0274
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.007 0.013 0.6858
Leishmania major hypothetical protein, conserved 0.007 0.013 0.0116
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0058 0.005
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0095 0.0189 0.0189
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Brugia malayi beta-lactamase family protein 0.008 0.0155 0.1551
Leishmania major hypothetical protein, conserved 0.0095 0.0189 0.0176
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.0573 0.0573
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0046 0.0033
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0047 0.0047
Mycobacterium tuberculosis Conserved protein 0.008 0.0155 0.1286
Schistosoma mansoni hypothetical protein 0.0095 0.0189 0.0189
Onchocerca volvulus 0.008 0.0155 0.0141
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0115 0.0115
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0036 0.0048 0.0048
Brugia malayi AMP-binding enzyme family protein 0.0076 0.0143 0.1431
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0155
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.002
Trichomonas vaginalis beta lactamase domain, putative 0.0095 0.0189 0.1657
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0095 0.0189 0.1657
Mycobacterium tuberculosis Probable hydrolase 0.008 0.0155 0.1286
Schistosoma mansoni hypothetical protein 0.007 0.013 0.013
Echinococcus granulosus phosphoglycerate mutase 0.007 0.013 0.013
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0069 0.0069
Schistosoma mansoni cpg binding protein 0.0033 0.004 0.004
Echinococcus granulosus intestinal type alkaline phosphatase 0.016 0.0347 0.0347
Brugia malayi metallo-beta-lactamase superfamily protein 0.0095 0.0189 0.1896
Echinococcus multilocularis phosphoglycerate mutase 0.007 0.013 0.013
Schistosoma mansoni ferritin 0.0016 0.0000080918 0.0000080918
Leishmania major phosphoglycerate mutase protein, putative 0.007 0.013 0.0116
Mycobacterium ulcerans phosphoglycerate mutase 0.007 0.013 0.022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0043 0.0043
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.4154 1 1
Mycobacterium ulcerans phosphoglyceromutase 0.007 0.013 0.022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0043 0.0043
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.016 0.0347 0.0347
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0123 0.0257 0.2577
Mycobacterium leprae POSSIBLE HYDROLASE 0.0095 0.0189 1
Schistosoma mansoni alkaline phosphatase 0.016 0.0347 0.0347
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0058 0.0098
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0155 0.1356
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Schistosoma mansoni hypothetical protein 0.0095 0.0189 0.0189
Echinococcus granulosus expressed protein 0.0016 0.0000080918 0.0000080918
Loa Loa (eye worm) hypothetical protein 0.0048 0.0077 0.0077
Toxoplasma gondii ABC1 family protein 0.008 0.0155 0.804
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0116
Mycobacterium ulcerans acid phosphatase 0.007 0.013 0.022
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.007 0.013 0.0116
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.007 0.013 0.6858
Onchocerca volvulus Alhambra homolog 0.0028 0.0028 0.0015
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.007 0.013 0.6858
Loa Loa (eye worm) hypothetical protein 0.016 0.0347 0.0347
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0014 0.0138
Trypanosoma cruzi phosphoglycerate mutase, putative 0.007 0.013 0.0116
Echinococcus granulosus phosphoglycerate mutase 0.007 0.013 0.013
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0058 0.2507
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0004 0.0004
Trichomonas vaginalis apoptosis inducing factor, putative 0.0095 0.0189 0.1657
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0014 0.0007
Schistosoma mansoni zinc phosphodiesterase 0.0095 0.0189 0.0189
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.007 0.013 0.0116
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0028
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0095 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.0095 0.0189 0.0189
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0115 0.0115
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0072 0.0058
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0058 0.0058
Toxoplasma gondii exonuclease III APE 0.004 0.0058 0.2507
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.2452 0.5885 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0043 0.0429
Entamoeba histolytica metallo-beta-lactamase family protein 0.0095 0.0189 0.0299
Brugia malayi beta-lactamase family protein 0.008 0.0155 0.1551
Plasmodium falciparum phosphoglucomutase-2 0.007 0.013 0.6612
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Schistosoma mansoni ferritin light chain 0.0016 0.0000080918 0.0000080918
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0155 0.1356
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.1773 0.4244 0.4236
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0095 0.0189 0.0299
Echinococcus multilocularis phosphoglycerate mutase 0.007 0.013 0.013
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0014 0.0726
Echinococcus multilocularis intestinal type alkaline phosphatase 0.016 0.0347 0.0347
Echinococcus multilocularis peregrin 0.0028 0.0028 0.0028
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.0095 0.0189 1
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0573 0.5023
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.08 0.1894 0.1894
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0719 0.1697 0.1697
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0014 0.0114
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0043 0.0029
Mycobacterium leprae conserved hypothetical protein 0.0095 0.0189 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0108 0.5401
Mycobacterium tuberculosis Possible hydrolase MutT1 0.007 0.013 0.1078
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0088 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0573 0.5023
Echinococcus granulosus GPCR family 2 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.013 0.1078
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.0573 0.5744
Leishmania major metallo-beta-lactamase family-like protein 0.0095 0.0189 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0014 0.0138
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0155
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.007 0.013 0.0116
Brugia malayi hypothetical protein 0.0035 0.0046 0.0457
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Echinococcus multilocularis FTZ F1 alpha 0.0123 0.0257 0.0257
Mycobacterium ulcerans Zn-dependent glyoxylase 0.0095 0.0189 0.0321
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0072 0.0631
Echinococcus multilocularis expressed protein 0.0016 0.0000080918 0.0000080918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0046 0.0046
Loa Loa (eye worm) oxidoreductase 0.0022 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0155 0.0155
Leishmania major phosphoglycerate mutase family member 5, putative 0.007 0.013 0.0116
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0115 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0043 0.0429
Echinococcus multilocularis alkaline phosphatase 0.016 0.0347 0.0347
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0043 0.0043
Echinococcus multilocularis phosphoglycerate mutase 0.007 0.013 0.013
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0072 0.0065
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0155 0.1356
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0043 0.0043
Echinococcus multilocularis phosphoglycerate mutase 0.007 0.013 0.013
Toxoplasma gondii phosphoglycerate mutase family protein 0.007 0.013 0.6612
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0089 0.0896
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0043 0.0043
Mycobacterium ulcerans hypothetical protein 0.008 0.0155 0.0263
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0043 0.0043
Trypanosoma cruzi glyoxalase II 0.0095 0.0189 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0056 0.0488
Echinococcus multilocularis phosphoglycerate mutase 0.007 0.013 0.013
Onchocerca volvulus Protein UBASH3A homolog 0.007 0.013 0.0116
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0069 0.0069
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0046 0.186
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0058 0.3051
Schistosoma mansoni hypothetical protein 0.0719 0.1697 0.1697
Echinococcus multilocularis GPCR, family 2 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.007 0.013 0.013
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0833
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.4084 0.9831 0.983
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.0095 0.0189 0.0176
Schistosoma mansoni lamin 0.0053 0.0089 0.0089
Mycobacterium tuberculosis Possible hydrolase 0.0095 0.0189 0.1571
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0043 0.0429
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0014 0.0114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.008 0.0155 0.1286
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0046 0.0406
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0049 0.0431
Onchocerca volvulus 0.007 0.013 0.0116
Mycobacterium leprae conserved hypothetical protein 0.007 0.013 0.6858
Mycobacterium tuberculosis Probable lipase LipE 0.008 0.0155 0.1286
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0014 0.0023
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.007 0.013 0.1078
Echinococcus multilocularis cpg binding protein 0.0033 0.004 0.004
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0095 0.0189 0.0176
Echinococcus granulosus lamin dm0 0.0053 0.0089 0.0089
Trypanosoma cruzi glyoxalase II 0.0095 0.0189 0.0176
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0014 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0026 0.0231
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0043 0.0043
Echinococcus granulosus zinc phosphodiesterase 0.0095 0.0189 0.0189
Brugia malayi UBASH3A protein homolog 0.007 0.013 0.13
Echinococcus granulosus peregrin 0.0028 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.013
Trichomonas vaginalis phosphoglycerate mutase, putative 0.007 0.013 0.1136
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0046 0.0406
Schistosoma mansoni intermediate filament proteins 0.0053 0.0089 0.0089
Mycobacterium tuberculosis Conserved protein 0.0095 0.0189 0.1571
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0058 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0069 0.0069
Entamoeba histolytica hypothetical protein 0.0035 0.0046 0.0054
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0043 0.0043
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0046 0.0406
Echinococcus granulosus ETHE1 protein 0.0095 0.0189 0.0189
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.0095 0.0189 0.0183
Leishmania major cleavage and polyadenylation specificity factor, putative 0.0095 0.0189 0.0176
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1773 0.4244 0.424
Mycobacterium ulcerans hypothetical protein 0.0076 0.0143 0.0242
Toxoplasma gondii phosphoglycerate mutase family protein 0.007 0.013 0.6612
Onchocerca volvulus 0.008 0.0155 0.0141
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0097
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0058 0.0044
Trypanosoma cruzi phosphoglycerate mutase, putative 0.007 0.013 0.0116
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0029 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0027 0.0237
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.0998 0.0998
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0069 0.0069
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0043 0.0043
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0046 0.0465
Giardia lamblia Hypothetical protein 0.2452 0.5885 1
Trichomonas vaginalis phosphoglycerate mutase, putative 0.007 0.013 0.1136
Brugia malayi Pre-SET motif family protein 0.0062 0.011 0.1107
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0095 0.0189 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0043 0.0043
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0029 0.0295
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.007 0.013 0.013
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0006 0.0052
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.007 0.013 0.0116
Plasmodium falciparum acyl-CoA synthetase 0.0056 0.0097 0.4722
Loa Loa (eye worm) beta-lactamase 0.008 0.0155 0.0155
Schistosoma mansoni 6-phosphofructokinase 0.4154 1 1
Trypanosoma cruzi glycerolphosphate mutase, putative 0.007 0.013 0.0116
Mycobacterium leprae conserved hypothetical protein 0.008 0.0155 0.8182
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0049 0.0043
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0043 0.0429
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0155
Mycobacterium ulcerans acyl-CoA synthetase 0.0076 0.0143 0.0242
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0115 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0049 0.0431
Leishmania major 4-coumarate:coa ligase-like protein 0.0076 0.0143 0.0129
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0036 0.0036
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0189 0.1657
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.007 0.013 0.1078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Leishmania major hypothetical protein, conserved 0.008 0.0155 0.0141
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0047 0.0047
Mycobacterium ulcerans beta-lactamase 0.008 0.0155 0.0263
Entamoeba histolytica metallo-beta-lactamase family protein 0.0095 0.0189 0.0299
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0089 0.0089
Schistosoma mansoni coup transcription factor 0.0034 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0072 0.0631
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Mycobacterium leprae Possible phosphoglycerate mutase 0.007 0.013 0.6858
Entamoeba histolytica metallo-beta-lactamase family protein 0.0095 0.0189 0.0299
Leishmania major hypothetical protein, conserved 0.007 0.013 0.0116
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0184 0.0184
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0043 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0115 0.0115
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.011 0.011
Leishmania major 4-coumarate:coa ligase-like protein 0.0076 0.0143 0.0129
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0072 0.0072
Mycobacterium ulcerans hypothetical protein 0.0095 0.0189 0.0321
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0089 0.074
Onchocerca volvulus 0.4154 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.018
Trichomonas vaginalis beta lactamase domain, putative 0.0095 0.0189 0.1657
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0115 0.1157
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0058 0.0506
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1773 0.4244 0.4236
Brugia malayi metallo-beta-lactamase superfamily protein 0.0095 0.0189 0.1896
Leishmania major 4-coumarate:coa ligase-like protein 0.0076 0.0143 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0072 0.0631
Brugia malayi steroid hormone receptor 0.0034 0.0043 0.0429
Schistosoma mansoni hypothetical protein 0.007 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi intermediate filament protein 0.0053 0.0089 0.0896
Brugia malayi PHD-finger family protein 0.0028 0.0028 0.0285
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0043 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0049 0.0431
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0116
Mycobacterium ulcerans hydrolase 0.0095 0.0189 0.0321
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0095 0.0189 0.0176
Trypanosoma brucei glucosidase, putative 0.0036 0.0046 0.004
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0097
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.4154 1 1
Entamoeba histolytica alkyl sulfatase, putative 0.0095 0.0189 0.0299
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0043 0.0429
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.007 0.013 0.0197
Loa Loa (eye worm) hypothetical protein 0.0052 0.0087 0.0087
Mycobacterium leprae conserved hypothetical protein 0.007 0.013 0.6858
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0046 0.0056
Brugia malayi nuclear hormone receptor 0.0034 0.0043 0.0429
Echinococcus multilocularis phosphoglycerate mutase 0.007 0.013 0.013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.0179
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.011 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0089 0.074
Brugia malayi hypothetical protein 0.0095 0.0189 0.1896
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.008 0.0155 0.0155
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0046 0.0046
Trichomonas vaginalis phosphoglycerate mutase, putative 0.007 0.013 0.1136
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.0095 0.0189 1
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0014 0.0138
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0349 0.0349
Mycobacterium tuberculosis Conserved protein 0.0095 0.0189 0.1571
Loa Loa (eye worm) hypothetical protein 0.0053 0.0089 0.0089
Mycobacterium tuberculosis Possible hydrolase 0.0095 0.0189 0.1571
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0014 0.0726
Plasmodium falciparum cytosolic glyoxalase II 0.0095 0.0189 1
Schistosoma mansoni alpha-glucosidase 0.0138 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.007 0.013 0.0116
Entamoeba histolytica hypothetical protein 0.0035 0.0046 0.0054
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.4154 1 1
Mycobacterium ulcerans phosphoglycerate mutase 0.007 0.013 0.022
Loa Loa (eye worm) hypothetical protein 0.0076 0.0143 0.0143
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0043 0.0043
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0095 0.0189 0.0299
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0043 0.0043
Leishmania major metallo-beta-lactamase family protein-like protein 0.0095 0.0189 0.0176
Entamoeba histolytica hypothetical protein, conserved 0.0095 0.0189 0.0299
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0058 0.0479
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0349 0.0349
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.007 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0048 0.0076 0.0076
Mycobacterium ulcerans hypothetical protein 0.007 0.013 0.022
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0155 0.1356
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0103 0.0103
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.007 0.013 0.0123
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0095 0.0189 0.0176
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0115 0.0115
Toxoplasma gondii phosphoglycerate mutase family protein 0.007 0.013 0.6612
Schistosoma mansoni phosphoglycerate mutase 0.007 0.013 0.013
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.008 0.0155 0.0263
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0014 0.0007
Echinococcus granulosus phosphoglycerate mutase 0.007 0.013 0.013
Trypanosoma cruzi glycerolphosphate mutase, putative 0.007 0.013 0.0116
Trichomonas vaginalis beta lactamase domain, putative 0.0095 0.0189 0.1657
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0058 0.0579
Mycobacterium ulcerans hypothetical protein 0.2452 0.5885 1
Trypanosoma cruzi glyoxalase II 0.0095 0.0189 0.0176
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0046 0.0406
Echinococcus multilocularis ETHE1 protein 0.0095 0.0189 0.0189
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0189 0.1657
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.007 0.013 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0043 0.0429
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0046 0.0056
Echinococcus multilocularis beta LACTamase domain containing family member 0.008 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.2381 0.5716 0.5716
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.0095 0.0189 0.0183
Onchocerca volvulus 0.0048 0.0076 0.0062
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.007 0.013 0.0123
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0027 0.0237
Mycobacterium tuberculosis Conserved hypothetical protein 0.0095 0.0189 0.1571
Onchocerca volvulus 0.0095 0.0189 0.0176
Onchocerca volvulus 0.007 0.013 0.0116
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0014 0.0138
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0095 0.0189 0.0274
Mycobacterium ulcerans glyoxalase II, GloB 0.0095 0.0189 0.0321
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0116
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.4084 0.9831 0.983
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0043 0.0043
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.007 0.013 0.0197
Entamoeba histolytica hypothetical protein 0.0035 0.0046 0.0054
Echinococcus granulosus ferritin 0.0016 0.0000080918 0.0000080918
Echinococcus granulosus choline:ethanolamine kinase 0.0041 0.006 0.006
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0014 0.0138
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.2452 0.5885 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0155
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0123 0.0257 0.2577
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0056 0.0097 0.0802
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.007 0.013 0.358
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.011 0.011
Entamoeba histolytica hypothetical protein 0.0035 0.0046 0.0054
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.007 0.013 0.022
Onchocerca volvulus 0.007 0.013 0.0116
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Schistosoma mansoni ferritin light chain 0.0016 0.0000080918 0.0000080918
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0014 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0573 0.5023
Echinococcus granulosus geminin 0.0719 0.1697 0.1697
Plasmodium falciparum phd finger protein, putative 0.0028 0.0028 0.0833
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0069 0.0069
Onchocerca volvulus 0.0095 0.0189 0.0176
Mycobacterium ulcerans hypothetical protein 0.0095 0.0189 0.0321
Schistosoma mansoni hypothetical protein 0.0089 0.0175 0.0175
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0155 0.0141
Onchocerca volvulus 0.0076 0.0143 0.0129
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0056 0.0097 0.0164
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0095 0.0189 0.0189
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0014 0.0726
Leishmania major glycerolphosphate mutase, putative 0.007 0.013 0.0116
Entamoeba histolytica type A flavoprotein, putative 0.0095 0.0189 0.0299
Mycobacterium tuberculosis Conserved protein 0.007 0.013 0.1078
Onchocerca volvulus 0.0031 0.0036 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0004 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0095 0.0189 0.1571
Schistosoma mansoni ap endonuclease 0.004 0.0058 0.0058
Mycobacterium tuberculosis Probable esterase LipL 0.008 0.0155 0.1286
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0573 0.5023
Mycobacterium leprae Beta-lactamase-like protein 0.0095 0.0189 1
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0384 0.3365
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0014 0.0014
Brugia malayi hypothetical protein 0.0018 0.0004 0.0038
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0046 0.0046
Schistosoma mansoni alpha-glucosidase 0.0138 0.0295 0.0295
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0076 0.0143 0.0242
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0043 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.0143 0.0143
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0043 0.0043
Plasmodium vivax phosphoglucomutase-2, putative 0.007 0.013 0.6612
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0049 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0027 0.0237
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0095 0.0189 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0043 0.0429
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Trichomonas vaginalis phosphoglycerate mutase, putative 0.007 0.013 0.1136
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0072 0.0072
Schistosoma mansoni apoferritin-2 0.0016 0.0000080918 0.0000080918
Schistosoma mansoni cpg binding protein 0.0033 0.004 0.004
Mycobacterium ulcerans lipase LipD 0.008 0.0155 0.0263
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.0095 0.0189 0.1896
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0028 0.0028
Echinococcus multilocularis choline:ethanolamine kinase 0.0041 0.006 0.006
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0043 0.0043
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0014 0.0023
Onchocerca volvulus Protein UBASH3A homolog 0.007 0.013 0.0116
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0043 0.0043
Plasmodium vivax unspecified product 0.0095 0.0189 1
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.007 0.013 0.1078
Mycobacterium tuberculosis Conserved protein 0.008 0.0155 0.1286
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0049 0.0036
Treponema pallidum phosphoglyceromutase 0.007 0.013 0.6858
Onchocerca volvulus 0.016 0.0347 0.0334
Leishmania major phosphoglycerate mutase, putative 0.007 0.013 0.0116
Brugia malayi RNA binding protein 0.0064 0.0115 0.1157
Brugia malayi Bromodomain containing protein 0.0028 0.0028 0.0285
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0043 0.0029
Echinococcus granulosus tumor protein p63 0.0326 0.0749 0.0749
Mycobacterium leprae conserved hypothetical protein 0.007 0.013 0.6858
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0014 0.0114
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.007 0.013 0.6858
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0095 0.0189 0.0189
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0043 0.0043
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.011 0.5512
Trichomonas vaginalis phosphoglycerate mutase, putative 0.007 0.013 0.1136
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Onchocerca volvulus 0.0062 0.011 0.0097
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0089 0.0089
Toxoplasma gondii phosphotransferase enzyme family protein 0.0041 0.006 0.2631
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0014 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0046 0.0406
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.4154 1 1
Schistosoma mansoni cpg binding protein 0.0031 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0095 0.0189 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0043 0.0429
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Echinococcus granulosus tar DNA binding protein 0.0064 0.0115 0.0115
Entamoeba histolytica alkyl sulfatase, putative 0.0095 0.0189 0.0299
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0095 0.0189 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0043 0.0429
Brugia malayi phosphoglycerate mutase family protein 0.007 0.013 0.13
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0049 0.0431
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.007 0.013 0.0123
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0095 0.0189 0.0189
Brugia malayi TAR-binding protein 0.0064 0.0115 0.1157
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0043 0.0043
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0014 0.0023
Mycobacterium ulcerans hydrolase MutT1 0.007 0.013 0.022
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0833
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0095 0.0189 0.1571
Mycobacterium leprae probable isochorismate synthase EntC 0.007 0.013 0.6858
Plasmodium vivax phosphoglycerate mutase, putative 0.007 0.013 0.6612
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0043 0.0043
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0014 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0189 0.1657
Schistosoma mansoni alkaline phosphatase 0.016 0.0347 0.0347
Mycobacterium tuberculosis Conserved protein 0.008 0.0155 0.1286
Loa Loa (eye worm) hypothetical protein 0.0095 0.0189 0.0189
Brugia malayi beta-lactamase 0.008 0.0155 0.1551
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0043 0.0043
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0095 0.0189 0.0189
Mycobacterium tuberculosis Beta lactamase like protein 0.0095 0.0189 0.1571
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0097
Mycobacterium ulcerans hypothetical protein 0.007 0.013 0.022
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0014 0.0014
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0072 0.0099
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0095 0.0189 0.0176
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0043 0.0043
Echinococcus granulosus microtubule associated protein 2 0.1354 0.3232 0.3232
Schistosoma mansoni apoferritin-2 0.0016 0.0000080918 0.0000080918
Echinococcus granulosus phosphoglycerate mutase 0.007 0.013 0.013
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0043 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0046 0.0033
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.007 0.013 0.0197
Brugia malayi ecdysteroid receptor 0.0034 0.0043 0.0429
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0043 0.0043
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0076 0.0143 0.0242
Leishmania major hypothetical protein, unknown function 0.007 0.013 0.0116
Schistosoma mansoni lamin 0.0053 0.0089 0.0089
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Schistosoma mansoni hypothetical protein 0.0095 0.0189 0.0189
Brugia malayi phosphoglycerate mutase family protein 0.007 0.013 0.13
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0095 0.0189 0.0189
Schistosoma mansoni hypothetical protein 0.007 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Toxoplasma gondii phosphoglycerate mutase family protein 0.007 0.013 0.6612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0033 0.0287
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0097
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0047 0.0047
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0046 0.0406
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0072 0.0065
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0014 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0046 0.0406
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0014 0.0114
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0095 0.0189 0.0274
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0072 0.0058
Entamoeba histolytica type A flavoprotein, putative 0.0095 0.0189 0.0299
Mycobacterium ulcerans hydrolase 0.0095 0.0189 0.0321
Brugia malayi Choline/ethanolamine kinase family protein 0.0041 0.006 0.0601
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.007 0.013 0.1078
Onchocerca volvulus 0.0053 0.0089 0.0076
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0043 0.0429
Echinococcus multilocularis microtubule associated protein 2 0.1354 0.3232 0.3232
Mycobacterium ulcerans beta lactamase-like protein 0.0095 0.0189 0.0321
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0514 0.1203 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0014 0.0114
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0014 0.0114
Schistosoma mansoni hypothetical protein 0.0083 0.0161 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0076 0.0143 0.1431
Mycobacterium tuberculosis Conserved protein 0.0095 0.0189 0.1571
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0046 0.0033
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.007 0.013 0.022
Brugia malayi nuclear receptor RXR 0.0018 0.0004 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0026 0.0231
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0014 0.0023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.008 0.0155 0.1551
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0014 0.0023
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0115 0.0115
Onchocerca volvulus 0.0034 0.0043 0.0029
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.016 0.0347 0.0347
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.0001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0058 0.2507
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0072 0.0058
Brugia malayi jmjC domain containing protein 0.0092 0.0184 0.184
Entamoeba histolytica acyl-CoA synthetase, putative 0.0076 0.0143 0.022
Echinococcus granulosus phosphoglycerate mutase 0.007 0.013 0.013
Mycobacterium ulcerans acyl-CoA synthetase 0.0076 0.0143 0.0242
Echinococcus granulosus beta LACTamase domain containing family member 0.008 0.0155 0.0155
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0043 0.0043
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0089 0.074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.4084 0.9831 0.9831
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0036 0.0047 0.0472
Schistosoma mansoni phosphoglycerate mutase 0.007 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.007 0.013 0.1136
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.016 0.0347 0.0347
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0095 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0049 0.0431
Wolbachia endosymbiont of Brugia malayi metallo-beta-lactamase superfamily hydrolase 0.0095 0.0189 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0058 0.0044
Schistosoma mansoni zinc phosphodiesterase 0.0095 0.0189 0.0189
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0014 0.0023
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.016 0.0347 0.0347
Mycobacterium tuberculosis Probable conserved lipoprotein 0.008 0.0155 0.1286
Onchocerca volvulus 0.0488 0.1141 0.1128
Trichomonas vaginalis set domain proteins, putative 0.0488 0.1141 1
Mycobacterium ulcerans esterase/lipase LipP 0.008 0.0155 0.0263
Echinococcus multilocularis lamin 0.0053 0.0089 0.0089
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0076 0.0143 0.7546
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0048
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0184 0.0184
Trichomonas vaginalis beta lactamase domain, putative 0.0095 0.0189 0.1657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0021 0.0179
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0155
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0123 0.0257 0.0257
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0123 0.0257 0.0257
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0095 0.0189 0.0189
Plasmodium falciparum phosphoglycerate mutase, putative 0.007 0.013 0.6612
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0058 0.0075
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1773 0.4244 0.4236
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0043 0.0429
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0046 0.0406
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0138 0.0138
Brugia malayi ethe1-prov protein 0.0095 0.0189 0.1896
Mycobacterium tuberculosis Probable lipase LipD 0.008 0.0155 0.1286
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0043 0.0043
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0055 0.0055
Trichomonas vaginalis A-type flavoprotein 0.0095 0.0189 0.1657
Mycobacterium ulcerans hydrolase 0.0095 0.0189 0.0321
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.007 0.013 0.1078
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0088 0.0881
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0023 0.0023
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0043 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0014 0.0138
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0014 0.0114
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0076 0.0143 0.0143
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0055 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0189 0.1657
Mycobacterium ulcerans hypothetical protein 0.0095 0.0189 0.0321
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0384 0.3365
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0043 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0069 0.0689
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0349 0.3495
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0014 0.0023
Schistosoma mansoni microtubule-associated protein tau 0.1354 0.3232 0.3232
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0035 0.0046 0.0046
Loa Loa (eye worm) choline/ethanolamine kinase 0.0041 0.006 0.006
Echinococcus granulosus FTZ F1 alpha 0.0452 0.1052 0.1052
Treponema pallidum ribonuclease Z 0.0095 0.0189 1
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0362 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0076 0.0143 0.1431
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0058 0.3051
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0072 0.0723
Schistosoma mansoni ap endonuclease 0.004 0.0058 0.0058
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0014 0.0114
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0123
Loa Loa (eye worm) hypothetical protein 0.4154 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0014 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0043 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.011 0.011
Schistosoma mansoni hypothetical protein 0.007 0.013 0.013
Brugia malayi CXXC zinc finger family protein 0.0031 0.0036 0.0357
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0072 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0362 0.3175
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0004 0.0004
Mycobacterium leprae Probable lipase LipE 0.008 0.0155 0.8182
Entamoeba histolytica acyl-coA synthetase, putative 0.0076 0.0143 0.022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0043 0.0043
Brugia malayi MH2 domain containing protein 0.0242 0.0544 0.5455
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0028 0.0028
Onchocerca volvulus 0.008 0.0155 0.0141
Plasmodium vivax acyl-CoA synthetase, putative 0.0056 0.0097 0.4722
Brugia malayi nuclear receptor NHR-88 0.0034 0.0043 0.0429
Entamoeba histolytica acyl-CoA synthetase, putative 0.0076 0.0143 0.022
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0076 0.0143 0.7546
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.0095 0.0189 0.0183
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0123 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0573 0.5023
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.0001
Brugia malayi hypothetical protein 0.016 0.0347 0.3481
Trichomonas vaginalis beta lactamase domain, putative 0.0095 0.0189 0.1657
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0048 0.0476
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.007 0.013 0.0123
Mycobacterium ulcerans hypothetical protein 0.0095 0.0189 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0189 0.1657
Trichomonas vaginalis beta lactamase domain, putative 0.0095 0.0189 0.1657

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 1.39 uM Agonist activity at vitamin D3 receptor in human HL-60 cells assessed as induction of cell differentiation after 96 hrs by NBT dye-based microscopic analysis ChEMBL. 26562542

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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