Detailed information for compound 322471

Basic information

Technical information
  • TDR Targets ID: 322471
  • Name: (E)-4-[[(2S)-1-[[(2S)-1-[[12-[[(2S)-1-[[(2S)- 1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-me thyl-1-oxopentan-2-yl]amino]-12-oxododecyl]am ino]-3-(4-hydroxy-3-nitrophenyl)-1-oxopropan- 2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]ami no]-4-oxobut-2-enoic acid
  • MW: 934.128 | Formula: C49H71N7O11
  • H donors: 8 H acceptors: 11 LogP: 8.72 Rotable bonds: 36
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCC([C@@H](C(=O)N[C@H](C(=O)N)Cc1ccccc1)NC(=O)CCCCCCCCCCCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)/C=C/C(=O)O)CC1CCCCC1)Cc1ccc(c(c1)[N+](=O)[O-])O)C
  • InChi: 1S/C49H71N7O11/c1-3-33(2)45(49(65)53-37(46(50)62)29-34-19-13-11-14-20-34)55-42(58)23-17-9-7-5-4-6-8-10-18-28-51-47(63)38(31-36-24-25-41(57)40(32-36)56(66)67)54-48(64)39(30-35-21-15-12-16-22-35)52-43(59)26-27-44(60)61/h11,13-14,19-20,24-27,32-33,35,37-39,45,57H,3-10,12,15-18,21-23,28-31H2,1-2H3,(H2,50,62)(H,51,63)(H,52,59)(H,53,65)(H,54,64)(H,55,58)(H,60,61)/b27-26+/t33?,37-,38-,39-,45-/m0/s1
  • InChiKey: WKLDVJFSODUIPW-XSDGWBPSSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-4-[[(1S)-2-[[(1S)-2-[[12-[[(1S)-1-[[(1S)-2-amino-1-benzyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]amino]-12-oxo-dodecyl]amino]-1-[(4-hydroxy-3-nitro-phenyl)methyl]-2-oxo-ethyl]amino]-1-(cyclohexylmethyl)-2-oxo-ethyl]amino]-4-oxo-but-2-enoic acid
  • (E)-4-[[(1S)-2-[[(1S)-2-[[12-[[(1S)-1-[[[(1S)-2-amino-1-benzyl-2-oxoethyl]amino]-oxomethyl]-2-methylbutyl]amino]-12-oxododecyl]amino]-1-[(4-hydroxy-3-nitrophenyl)methyl]-2-oxoethyl]amino]-1-(cyclohexylmethyl)-2-oxoethyl]amino]-4-oxo-2-butenoic acid
  • (E)-4-[[(2S)-1-[[(2S)-1-[[12-[[(2S)-1-[[(2S)-1-azanyl-1-oxo-3-phenyl-propan-2-yl]amino]-3-methyl-1-oxo-pentan-2-yl]amino]-12-oxo-dodecyl]amino]-3-(4-hydroxy-3-nitro-phenyl)-1-oxo-propan-2-yl]amino]-3-cyclohexyl-1-oxo-propan-2-yl]amino]-4-oxo-but-2-enoic acid
  • (E)-4-[[(1S)-2-[[(1S)-2-[[12-[[(1S)-1-[[(1S)-2-amino-1-benzyl-2-keto-ethyl]carbamoyl]-2-methyl-butyl]amino]-12-keto-dodecyl]amino]-1-(4-hydroxy-3-nitro-benzyl)-2-keto-ethyl]amino]-1-(cyclohexylmethyl)-2-keto-ethyl]amino]-4-keto-but-2-enoic acid
  • (E)-4-[[(1S)-2-[[(1S)-2-[[12-[[(1S)-1-[[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]carbamoyl]-2-methyl-butyl]amino]-12-oxo-dodecyl]amino]-1-[(4-hydroxy-3-nitro-phenyl)methyl]-2-oxo-ethyl]amino]-1-(cyclohexylmethyl)-2-oxo-ethyl]amino]-4-oxo-but-2-enoic acid
  • (E)-4-[[(1S)-2-[[(1S)-2-[[12-[[(1S)-1-[[[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]amino]-oxomethyl]-2-methylbutyl]amino]-12-oxododecyl]amino]-1-[(4-hydroxy-3-nitrophenyl)methyl]-2-oxoethyl]amino]-1-(cyclohexylmethyl)-2-oxoethyl]amino]-4-oxobut-2-enoic acid
  • (E)-4-[[(1S)-2-[[(1S)-2-[[12-[[(1S)-1-[[(1S)-2-amino-1-(benzyl)-2-keto-ethyl]carbamoyl]-2-methyl-butyl]amino]-12-keto-dodecyl]amino]-1-(4-hydroxy-3-nitro-benzyl)-2-keto-ethyl]amino]-1-(cyclohexylmethyl)-2-keto-ethyl]amino]-4-keto-but-2-enoic acid
  • (E)-4-[[(2S)-1-[[(2S)-1-[[12-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenyl-propan-2-yl]amino]-3-methyl-1-oxo-pentan-2-yl]amino]-12-oxo-dodecyl]amino]-3-(4-hydroxy-3-nitro-phenyl)-1-oxo-propan-2-yl]amino]-3-cyclohexyl-1-oxo-propan-2-yl]amino]-4-oxo-but-2-enoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Cathepsin B precursor 0.0096 0.0337 0.2228
Loa Loa (eye worm) hypothetical protein 0.0076 0.0246 0.0415
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.0748 0.1436
Toxoplasma gondii histone deacetylase HDAC5 0.013 0.0486 0.0915
Entamoeba histolytica hypothetical protein 0.0036 0.0072 0.0479
Schistosoma mansoni opsin-like receptor 0.0044 0.0107 0.0107
Loa Loa (eye worm) histone deacetylase 1 0.0362 0.151 0.254
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0042 0.0099 0.0212
Toxoplasma gondii hypothetical protein 0.0035 0.0067 0.0111
Echinococcus granulosus importin subunit beta 1 0.003 0.0047 0.0091
Echinococcus granulosus hypothetical protein 0.0044 0.0107 0.0205
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.001 0.0019
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.001 0.0019
Schistosoma mansoni multidrug resistance protein 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0094 0.033 0.0554
Entamoeba histolytica P-glycoprotein-2 0.0022 0.001 0.0065
Brugia malayi Matrixin family protein 0.0062 0.0187 0.0314
Plasmodium vivax prefoldin subunit 6, putative 0.0064 0.0193 0.0377
Loa Loa (eye worm) endoprotease bli-4 0.0042 0.0099 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Echinococcus multilocularis orexin receptor type 2 0.0044 0.0107 0.0204
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0002 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0002 0.0002
Giardia lamblia Alanyl dipeptidyl peptidase 0.0126 0.0469 0.3101
Echinococcus granulosus glycoprotein Antigen 5 0.004 0.009 0.0173
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Trypanosoma brucei prefoldin subunit, putative 0.0064 0.0193 0.037
Schistosoma mansoni DNA polymerase eta 0.002 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0044 0.0107 0.0204
Toxoplasma gondii ABC1 family protein 0.0074 0.0241 0.0444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Onchocerca volvulus 0.004 0.009 0.0173
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0064 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0078 0.0259 0.0436
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0233 0.0445
Plasmodium falciparum plasmepsin IV 0.1127 0.4887 1
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0002 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0189 0.0748 0.1259
Loa Loa (eye worm) hypothetical protein 0.0153 0.0589 0.0991
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0196 0.0375
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0241 0.0516
Loa Loa (eye worm) matrixin family protein 0.0138 0.052 0.0875
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis transmembrane protease serine 3 0.004 0.009 0.0172
Schistosoma mansoni cathepsin D (A01 family) 0.2285 1 1
Schistosoma mansoni amine GPCR 0.0044 0.0107 0.0107
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0057 0.0165 0.0316
Trypanosoma cruzi subtilisin peptidase 0.0042 0.0099 0.0189
Loa Loa (eye worm) hypothetical protein 0.0151 0.0582 0.0979
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.0107 0.0205
Plasmodium falciparum plasmepsin IX 0.0655 0.2805 0.5732
Echinococcus multilocularis fmrfamide receptor 0.0044 0.0107 0.0204
Schistosoma mansoni hypothetical protein 0.0044 0.0107 0.0107
Echinococcus granulosus cathepsin b 0.0285 0.117 0.2245
Plasmodium falciparum histone deacetylase, putative 0.0257 0.1047 0.2127
Trypanosoma cruzi cysteine peptidase, putative 0.0025 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Mycobacterium ulcerans beta-lactamase 0.0074 0.0241 0.1188
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Loa Loa (eye worm) beta-lactamase 0.0074 0.0241 0.0405
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0012 0.0021
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0042 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Schistosoma mansoni histone deacetylase 0.0362 0.151 0.151
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0002 0.0003
Echinococcus granulosus calpain A 0.0162 0.0628 0.1204
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.013 0.0486 0.0817
Brugia malayi AKH receptor 0.0044 0.0107 0.018
Brugia malayi Kringle domain containing protein 0.0078 0.0259 0.0436
Echinococcus multilocularis histone deacetylase 1 0.0362 0.151 0.2897
Echinococcus granulosus apoptotic protease activating factor 1 0.0134 0.0507 0.0972
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0044 0.0107 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0002 0.0003
Echinococcus granulosus g protein coupled receptor 0.0044 0.0107 0.0205
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0334 0.1387 0.2334
Onchocerca volvulus 0.0025 0.0024 0.0047
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0047 0.0089
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.1483 0.2845
Echinococcus granulosus furin 0.0042 0.0099 0.0191
Echinococcus multilocularis caspase 2 0.0153 0.0589 0.1129
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0067 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0002 0.0003
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0126 0.0469 0.0898
Trypanosoma brucei subtilisin peptidase 0.0042 0.0099 0.0189
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Echinococcus granulosus geminin 0.0167 0.0649 0.1245
Brugia malayi Dopamine receptor 0.0044 0.0107 0.018
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0167
Loa Loa (eye worm) hypothetical protein 0.004 0.009 0.0152
Entamoeba histolytica P-glycoprotein-5 0.0022 0.001 0.0065
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0405
Onchocerca volvulus 0.0035 0.0067 0.0129
Loa Loa (eye worm) hypothetical protein 0.004 0.009 0.0152
Onchocerca volvulus Matrilysin homolog 0.0138 0.052 0.0998
Trypanosoma cruzi hypothetical protein, conserved 0.009 0.031 0.0594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Onchocerca volvulus 0.0035 0.0067 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0002 0.0003
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0334 0.1387 0.2334
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0126 0.0469 0.0882
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.002
Toxoplasma gondii microneme protein MIC4 0.0035 0.0067 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Echinococcus multilocularis histone deacetylase 6 0.0257 0.1047 0.2008
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.1483 0.2845
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0126 0.0469 0.0898
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.0107 0.0205
Brugia malayi Inositol-1 0.0075 0.0244 0.0411
Plasmodium falciparum histone deacetylase 2 0.0257 0.1047 0.2127
Echinococcus multilocularis cysteine protease 0.0025 0.0024 0.0046
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0057 0.0165 0.0316
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0042 0.0099 0.0099
Onchocerca volvulus Matrix metalloproteinase homolog 0.0138 0.052 0.0998
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0241 0.0516
Toxoplasma gondii microneme protein MIC17A 0.0035 0.0067 0.0111
Plasmodium falciparum plasmepsin I 0.1127 0.4887 1
Loa Loa (eye worm) calpain 5 0.004 0.009 0.0151
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.009 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0126 0.0469 0.0898
Giardia lamblia Cathepsin B precursor 0.0096 0.0337 0.2228
Plasmodium vivax aspartyl proteinase, putative 0.1127 0.4887 1
Schistosoma mansoni histone deacetylase hda2 0.013 0.0486 0.0486
Brugia malayi Protein kinase domain containing protein 0.0078 0.0259 0.0436
Loa Loa (eye worm) hypothetical protein 0.0112 0.0405 0.0682
Brugia malayi Histone deacetylase 1 0.0362 0.151 0.254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0044 0.0107 0.018
Schistosoma mansoni lamin 0.0028 0.0036 0.0036
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0044 0.0107 0.018
Onchocerca volvulus Cathepsin L homolog 0.0025 0.0024 0.0047
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.001 0.0017
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0099 0.0189
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0002 0.0002
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0044 0.0107 0.0204
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0067 0.021 0.0449
Trypanosoma cruzi oligopeptidase b 0.0477 0.202 0.3875
Onchocerca volvulus Prolyl endopeptidase homolog 0.12 0.5211 1
Schistosoma mansoni hypothetical protein 0.0036 0.0072 0.0072
Echinococcus multilocularis histone deacetylase 0.0257 0.1047 0.2008
Echinococcus multilocularis hypothetical protein 0.0057 0.0165 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0002 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Toxoplasma gondii prefoldin subunit 6, putative 0.0064 0.0193 0.0353
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0477 0.202 0.3875
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.0107 0.0205
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0901 0.0901
Onchocerca volvulus 0.0035 0.0067 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Onchocerca volvulus 0.0035 0.0067 0.0129
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Onchocerca volvulus 0.004 0.009 0.0173
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0002 0.0003
Brugia malayi Papain family cysteine protease containing protein 0.0025 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0002 0.0002
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.1366 0.5943 0.5943
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0477 0.202 0.3875
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0044 0.0107 0.0204
Echinococcus multilocularis Furin 1 0.0042 0.0099 0.0189
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0126 0.0469 0.0898
Brugia malayi prolyl oligopeptidase family protein 0.0126 0.0469 0.0789
Schistosoma mansoni hypothetical protein 0.0334 0.1387 0.1387
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0042 0.0099 0.0488
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Brugia malayi intermediate filament protein 0.0028 0.0036 0.006
Loa Loa (eye worm) TYRA-2 protein 0.0044 0.0107 0.018
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.002
Schistosoma mansoni hypothetical protein 0.0088 0.0301 0.0301
Schistosoma mansoni opsin-like receptor 0.0044 0.0107 0.0107
Schistosoma mansoni thyroid hormone receptor 0.002 0.0002 0.0002
Echinococcus granulosus Mastin 0.004 0.009 0.0173
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Echinococcus granulosus inhibitor of apoptosis protein 0.0334 0.1387 0.2662
Plasmodium falciparum subtilisin-like protease 3 0.0042 0.0099 0.0184
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0241 0.0493
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0196 0.0357
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0042 0.0099 0.0189
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0196 0.0196
Trichomonas vaginalis abcb9, putative 0.0022 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.004 0.009 0.0152
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0044 0.0107 0.018
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.002
Entamoeba histolytica P-glycoprotein-2 0.0022 0.001 0.0065
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0241 0.0461
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Echinococcus granulosus cathepsin l1 0.0025 0.0024 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0203
Onchocerca volvulus 0.004 0.009 0.0173
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0002 0.0002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni growth hormone secretagogue receptor 0.0044 0.0107 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.009 0.031 0.0594
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0241 0.0461
Echinococcus multilocularis g protein coupled receptor 0.0044 0.0107 0.0204
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.0107 0.0107
Schistosoma mansoni calpain-7 (C02 family) 0.0057 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.1127 0.4887 0.8222
Echinococcus multilocularis tissue type plasminogen activator 0.0078 0.0259 0.0496
Trypanosoma brucei antigen, putative 0.0057 0.0165 0.0316
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.151 0.309
Echinococcus multilocularis inositol monophosphatase 1 0.0075 0.0244 0.0467
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.004 0.009 0.009
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0244 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Brugia malayi G protein-coupled receptor 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0244 0.05
Brugia malayi follicle stimulating hormone receptor 0.0044 0.0107 0.018
Schistosoma mansoni amine GPCR 0.0044 0.0107 0.0107
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0099 0.0099
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0099 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0356 0.1483 0.2496
Loa Loa (eye worm) hypothetical protein 0.0362 0.151 0.254
Echinococcus multilocularis histone deacetylase 7 0.0257 0.1047 0.2008
Trypanosoma brucei cysteine peptidase C (CPC) 0.0096 0.0337 0.0645
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Trypanosoma brucei calpain-like protein, putative 0.0057 0.0165 0.0316
Echinococcus granulosus sex peptide receptor 0.0044 0.0107 0.0205
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0233 0.0445
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0044 0.0107 0.0204
Brugia malayi Eukaryotic aspartyl protease family protein 0.0312 0.1291 0.2172
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0036 0.006
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0172 0.0329
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0067 0.0113
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Mycobacterium ulcerans hydrolase 0.0076 0.0246 0.1217
Onchocerca volvulus 0.0025 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0001 0.0002
Echinococcus granulosus 7TM GPCR rhodopsin 0.0044 0.0107 0.0205
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Entamoeba histolytica Ran family GTPase 0.0022 0.0012 0.0078
Brugia malayi prolyl oligopeptidase family protein 0.0126 0.0469 0.0789
Brugia malayi nuclear receptor NHR-88 0.002 0.0002 0.0003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0044 0.0107 0.0204
Loa Loa (eye worm) trypsin family protein 0.004 0.009 0.0152
Toxoplasma gondii hypothetical protein 0.0035 0.0067 0.0111
Loa Loa (eye worm) hypothetical protein 0.0062 0.0187 0.0314
Brugia malayi larval opioid receptor 0.0044 0.0107 0.018
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0044 0.0107 0.0204
Loa Loa (eye worm) hypothetical protein 0.0182 0.0716 0.1204
Loa Loa (eye worm) hypothetical protein 0.0062 0.0187 0.0314
Onchocerca volvulus 0.0035 0.0067 0.0129
Entamoeba histolytica prolyl oligopeptidase family protein 0.0126 0.0469 0.3105
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0002 0.0003
Loa Loa (eye worm) calpain family protein 1 0.0112 0.0405 0.0682
Onchocerca volvulus 0.0062 0.0187 0.0358
Brugia malayi Ets-domain containing protein 0.0072 0.0229 0.0385
Plasmodium vivax aspartyl protease, putative 0.0655 0.2805 0.5732
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0044 0.0107 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0075 0.0244 0.1618
Brugia malayi Fli-1 protein 0.0217 0.0872 0.1467
Brugia malayi Matrixin family protein 0.0062 0.0187 0.0314
Loa Loa (eye worm) fli-1 protein 0.0217 0.0872 0.1467
Plasmodium vivax aspartyl proteinase, putative 0.0312 0.1291 0.2627
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Trypanosoma brucei oligopeptidase b 0.0477 0.202 0.3875
Leishmania major cathepsin L-like protease 0.0072 0.0233 0.0445
Schistosoma mansoni hypothetical protein 0.0023 0.0014 0.0014
Plasmodium falciparum plasmepsin II 0.1127 0.4887 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0017
Brugia malayi prolyl oligopeptidase family protein 0.12 0.5211 0.8768
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0241 0.1188
Onchocerca volvulus 0.0028 0.0036 0.0068
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0042 0.0099 0.0189
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Onchocerca volvulus Cell death protein 3 homolog 0.0153 0.0589 0.113
Trypanosoma cruzi prefoldin subunit, putative 0.0064 0.0193 0.037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0067 0.0113
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0057 0.0165 0.0316
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Giardia lamblia Alanyl dipeptidyl peptidase 0.0126 0.0469 0.3101
Brugia malayi Subtilase family protein 0.1366 0.5943 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.001 0.0065
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0044 0.0107 0.0204
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.12 0.5211 0.5211
Brugia malayi hypothetical protein 0.0036 0.0072 0.0122
Echinococcus granulosus p2X purinoceptor 4 0.0072 0.0229 0.0439
Brugia malayi neuroendocrine convertase 1 precursor 0.0042 0.0099 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0001 0.0005
Loa Loa (eye worm) histone deacetylase 0.0257 0.1047 0.1761
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.0107 0.0205
Schistosoma mansoni P2X receptor subunit 0.0072 0.0229 0.0229
Plasmodium vivax aspartyl protease, putative 0.0312 0.1291 0.2627
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.117 0.117
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0002 0.0002
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0061 0.0183 0.0308
Echinococcus multilocularis lamin 0.0028 0.0036 0.0067
Mycobacterium tuberculosis Conserved protein 0.0074 0.0241 0.0516
Schistosoma mansoni P2X receptor subunit 0.0072 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.004 0.009 0.0152
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0334 0.1387 0.2334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0512 0.2171 0.4166
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0009 0.0015
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0042 0.0099 0.0488
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0002 0.0002
Echinococcus granulosus histone deacetylase 6 0.0257 0.1047 0.2009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Echinococcus granulosus histone deacetylase 3 0.0362 0.151 0.2898
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.009 0.031 0.0616
Leishmania major hypothetical protein, conserved 0.0051 0.0137 0.0262
Leishmania major cathepsin L-like protease 0.0072 0.0233 0.0445
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0167
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.0469 0.0898
Echinococcus granulosus g-protein coupled receptor 0.0044 0.0107 0.0205
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0259 0.0496
Loa Loa (eye worm) fibroinase 0.0025 0.0024 0.0041
Onchocerca volvulus 0.0044 0.0107 0.0205
Toxoplasma gondii subtilisin SUB5 0.0042 0.0099 0.0172
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0126 0.0469 0.0882
Mycobacterium ulcerans hypothetical protein 0.004 0.009 0.0444
Schistosoma mansoni furin-1 (S08 family) 0.0042 0.0099 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0748 0.0748
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Onchocerca volvulus 0.0025 0.0024 0.0047
Echinococcus multilocularis geminin 0.0167 0.0649 0.1244
Plasmodium falciparum cysteine repeat modular protein 1 0.0078 0.0259 0.0511
Trypanosoma cruzi oligopeptidase b 0.0477 0.202 0.3875
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0241 0.0516
Onchocerca volvulus 0.0044 0.0107 0.0205
Echinococcus granulosus caspase 2 0.0153 0.0589 0.113
Echinococcus granulosus tachykinin peptides receptor 99D 0.0044 0.0107 0.0205
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0057 0.0165 0.0316
Loa Loa (eye worm) ctsf protein 0.0025 0.0024 0.0041
Loa Loa (eye worm) matrix metalloproteinase 0.0062 0.0187 0.0314
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus granulosus neuropeptide s receptor 0.0044 0.0107 0.0205
Entamoeba histolytica protein kinase, putative 0.004 0.009 0.0593
Loa Loa (eye worm) cysteine protease 0.0025 0.0024 0.0041
Onchocerca volvulus 0.0044 0.0107 0.0205
Onchocerca volvulus 0.0044 0.0107 0.0205
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0044 0.0107 0.018
Schistosoma mansoni hypothetical protein 0.004 0.009 0.009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Echinococcus granulosus calpain 5 0.0059 0.0174 0.0335
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0067 0.0113
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.002
Leishmania major cathepsin L-like protease 0.0025 0.0024 0.0046
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0025 0.0024 0.0041
Echinococcus granulosus p2X purinoceptor 4 0.0072 0.0229 0.0439
Trypanosoma brucei histone deacetylase 4 0.0257 0.1047 0.2008
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0002 0.0003
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0285 0.117 0.2244
Schistosoma mansoni calpain C (C02 family) 0.0057 0.0165 0.0165
Brugia malayi celfurPC protein 0.0042 0.0099 0.0167
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0137 0.0261
Leishmania major subtilisin-like serine peptidase 0.0042 0.0099 0.0189
Loa Loa (eye worm) calpain 0.0057 0.0165 0.0278
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0137 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0203
Onchocerca volvulus 0.0044 0.0107 0.0205
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.001 0.0016
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Brugia malayi Cathepsin L-like precursor 0.0025 0.0024 0.0041
Schistosoma mansoni neuropeptide receptor 0.0044 0.0107 0.0107
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0002 0.0002
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0076 0.0246 0.0415
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0512 0.2171 0.4165
Plasmodium vivax histone deacetylase 1, putative 0.0362 0.151 0.3076
Echinococcus granulosus cathepsin l cysteine peptidase 0.0025 0.0024 0.0047
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0012 0.0004
Mycobacterium tuberculosis Conserved protein 0.009 0.031 0.0665
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0014 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0469 0.0959
Toxoplasma gondii kringle domain-containing protein 0.0078 0.0259 0.0479
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0285 0.117 0.117
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0241 0.0461
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.0107 0.0107
Onchocerca volvulus 0.002 0.0002 0.0003
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0334 0.1387 0.1387
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Schistosoma mansoni multidrug resistance protein 0.0022 0.001 0.001
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0044 0.0107 0.0107
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0001 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.001 0.0019
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0036 0.006
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0405
Brugia malayi Dopamine receptor protein 2 0.0044 0.0107 0.018
Echinococcus multilocularis neuropeptide receptor 0.0044 0.0107 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0203
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0036 0.006
Schistosoma mansoni intermediate filament proteins 0.0028 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0224 0.0901 0.1517
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.0107 0.0107
Trypanosoma brucei histone deacetylase 3 0.0257 0.1047 0.2008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Toxoplasma gondii cathepsin B 0.0096 0.0337 0.0629
Loa Loa (eye worm) histone deacetylase 3 0.0362 0.151 0.254
Echinococcus multilocularis inhibitor of apoptosis protein 0.0334 0.1387 0.2661
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Toxoplasma gondii prolyl endopeptidase 0.12 0.5211 1
Leishmania major hypothetical protein, conserved 0.009 0.031 0.0594
Echinococcus granulosus g protein coupled receptor 0.0044 0.0107 0.0205
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0241 0.0241
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.151 0.309
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0405
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0241 0.0736
Brugia malayi RNA, U transporter 1 0.0086 0.0295 0.0496
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Brugia malayi Importin beta-1 subunit 0.003 0.0047 0.008
Leishmania major prefoldin subunit, putative 0.0064 0.0193 0.037
Loa Loa (eye worm) subtilase 0.1366 0.5943 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0012 0.0074
Onchocerca volvulus 0.004 0.009 0.0173
Brugia malayi Cell death protein 3 precursor 0.0153 0.0589 0.0991
Schistosoma mansoni importin beta-1 0.003 0.0047 0.0047
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0334 0.1387 0.2662
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Brugia malayi Ets-domain containing protein 0.0072 0.0229 0.0385
Leishmania major cathepsin L-like protease 0.0025 0.0024 0.0046
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0296 0.1219 0.1219
Onchocerca volvulus 0.0044 0.0107 0.0205
Leishmania major hypothetical protein, conserved 0.009 0.031 0.0594
Trypanosoma cruzi prolyl endopeptidase 0.12 0.5211 1
Leishmania major hypothetical protein, conserved 0.0074 0.0241 0.0461
Brugia malayi ecdysteroid receptor 0.002 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0025 0.0024 0.005
Brugia malayi Dopamine receptor protein 1 0.0044 0.0107 0.018
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0022 0.0045
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.004 0.009 0.0172
Schistosoma mansoni lamin 0.0028 0.0036 0.0036
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0233 0.0445
Plasmodium vivax aspartyl protease, putative 0.0655 0.2805 0.5732
Echinococcus multilocularis cathepsin b 0.0285 0.117 0.2244
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Echinococcus multilocularis calpain 0.0057 0.0165 0.0316
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0002 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0244 0.0467
Trichomonas vaginalis ran, putative 0.0022 0.0012 0.0024
Schistosoma mansoni smdr2 0.0022 0.001 0.001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0044 0.0107 0.0204
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Onchocerca volvulus Neuropeptide F receptor homolog 0.0044 0.0107 0.0205
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0044 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0748 0.0748
Onchocerca volvulus 0.0074 0.0241 0.0462
Loa Loa (eye worm) calpain family protein 1 0.0151 0.0582 0.0979
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0002 0.0003
Toxoplasma gondii PAN domain-containing protein 0.0326 0.1351 0.2579
Brugia malayi hypothetical protein 0.0033 0.0058 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0002 0.0003
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0075 0.0244 0.1206
Entamoeba histolytica hypothetical protein 0.0036 0.0072 0.0479
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0096 0.0337 0.0645
Loa Loa (eye worm) hypothetical protein 0.003 0.0047 0.008
Echinococcus granulosus transmembrane protease serine 3 0.004 0.009 0.0173
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0002 0.0002
Onchocerca volvulus 0.004 0.009 0.0173
Schistosoma mansoni adenoreceptor 0.0044 0.0107 0.0107
Entamoeba histolytica histone deacetylase, putative 0.0362 0.151 1
Onchocerca volvulus 0.0044 0.0107 0.0205
Onchocerca volvulus 0.0074 0.0241 0.0462
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1074 0.4655 1
Loa Loa (eye worm) hypothetical protein 0.12 0.5211 0.8768
Plasmodium falciparum plasmepsin V 0.0312 0.1291 0.2627
Loa Loa (eye worm) hypothetical protein 0.0224 0.0901 0.1517
Loa Loa (eye worm) hypothetical protein 0.0312 0.1291 0.2172
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.1127 0.4887 0.4887
Onchocerca volvulus 0.0042 0.0099 0.0191
Plasmodium vivax subtilisin-like protease 2, putative 0.0042 0.0099 0.0184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Plasmodium vivax vivapain-2 0.0025 0.0024 0.003
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0075 0.0244 0.0451
Brugia malayi ORL1-like opioid receptor 0.0044 0.0107 0.018
Onchocerca volvulus Matrilysin homolog 0.0062 0.0187 0.0358
Loa Loa (eye worm) histone deacetylase 11 0.013 0.0486 0.0817
Brugia malayi beta-lactamase family protein 0.0074 0.0241 0.0405
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.1127 0.4887 0.9377
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0229 0.0438
Brugia malayi endoprotease bli-4 precursor 0.0042 0.0099 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0334 0.1387 0.2661
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Echinococcus granulosus orexin receptor type 2 0.0044 0.0107 0.0205
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0162 0.0627 0.0627
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0002 0.0003
Brugia malayi steroid hormone receptor 0.002 0.0002 0.0003
Treponema pallidum mcbG protein 0.009 0.031 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.0107 0.0205
Brugia malayi aspartic protease BmAsp-2, identical 0.0312 0.1291 0.2172
Brugia malayi Tachykinin-like peptides receptor 99D 0.0044 0.0107 0.018
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0002 0.0003
Leishmania major histone deacetylase, putative 0.0257 0.1047 0.2008
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0241 0.0461
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.0469 0.0898
Echinococcus multilocularis somatostatin receptor 0.0044 0.0107 0.0204
Leishmania major cathepsin L-like protease 0.0025 0.0024 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Brugia malayi hypothetical protein 0.0134 0.0507 0.0852
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0042 0.0099 0.0099
Loa Loa (eye worm) TK/ROR protein kinase 0.0078 0.0259 0.0436
Loa Loa (eye worm) hypothetical protein 0.0134 0.0507 0.0852
Echinococcus granulosus dna polymerase eta 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.009 0.0152
Echinococcus granulosus dro:myosuppressin receptor 0.0044 0.0107 0.0205
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0024 0.0024
Echinococcus multilocularis G-protein coupled receptor, putative 0.0044 0.0107 0.0204
Loa Loa (eye worm) hypothetical protein 0.0051 0.0137 0.0231
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Brugia malayi multidrug resistance protein 3 0.0022 0.001 0.0016
Mycobacterium tuberculosis Conserved protein 0.0074 0.0241 0.0516
Echinococcus multilocularis neuropeptide s receptor 0.0044 0.0107 0.0204
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.0107 0.0204
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Plasmodium vivax plasmepsin IV, putative 0.1127 0.4887 1
Onchocerca volvulus 0.0025 0.0024 0.0047
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0096 0.0337 0.069
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis fmrfamide receptor 0.0044 0.0107 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0244 0.05
Toxoplasma gondii subtilisin SUB6 0.0042 0.0099 0.0172
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0748 0.0748
Brugia malayi Trypsin family protein 0.0224 0.0901 0.1517
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.004 0.009 0.0173
Echinococcus multilocularis p2X purinoceptor 4 0.0072 0.0229 0.0438
Schistosoma mansoni histone deacetylase 4 5 0.0257 0.1047 0.1047
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0151 0.0582 0.0582
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0044 0.0107 0.0205
Trichomonas vaginalis esterase, putative 0.0074 0.0241 0.0493
Trypanosoma cruzi histone deacetylase 1, putative 0.0362 0.151 0.2897
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0044 0.0107 0.0204
Onchocerca volvulus 0.0312 0.1291 0.2477
Echinococcus granulosus dna polymerase kappa 0.002 0.0001 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0002 0.0002
Echinococcus multilocularis cysteine protease 0.0025 0.0024 0.0046
Brugia malayi Cathepsin L-like precursor 0.0025 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis 0.0042 0.0099 0.0189
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0022 0.0041
Onchocerca volvulus 0.0044 0.0107 0.0205
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0009 0.0017
Echinococcus multilocularis glycoprotein Antigen 5 0.004 0.009 0.0172
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0477 0.202 0.3875
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0057 0.0165 0.0316
Mycobacterium leprae PROBABLE HYDROLASE 0.0076 0.0246 0.0766
Echinococcus granulosus calpain 7 C02 family 0.0057 0.0165 0.0317
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0019
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.002
Trypanosoma cruzi histone deacetylase, putative 0.0257 0.1047 0.2008
Brugia malayi histone deacetylase 1 (HD1) 0.0362 0.151 0.254
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.001 0.0016
Loa Loa (eye worm) aspartyl protease 6 0.0312 0.1291 0.2172
Onchocerca volvulus 0.0025 0.0024 0.0047
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Trypanosoma cruzi histone deacetylase, putative 0.0257 0.1047 0.2008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0001 0.0001
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Toxoplasma gondii subtilisin SUB9 0.0042 0.0099 0.0172
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0002 0.0003
Echinococcus multilocularis lamin dm0 0.0028 0.0036 0.0067
Entamoeba histolytica hypothetical protein 0.0036 0.0072 0.0479
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni histone deacetylase 4 5 0.0257 0.1047 0.1047
Brugia malayi putative neuropeptide receptor NPR1 0.0044 0.0107 0.018
Loa Loa (eye worm) histone deacetylase 7A 0.0257 0.1047 0.1761
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.0107 0.0107
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.0107 0.0107
Echinococcus granulosus calpain A 0.0057 0.0165 0.0317
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0019
Echinococcus multilocularis serotonin receptor 0.0044 0.0107 0.0204
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0047 0.0072
Loa Loa (eye worm) hypothetical protein 0.004 0.009 0.0152
Brugia malayi Matrixin family protein 0.0062 0.0187 0.0314
Schistosoma mansoni nuclear hormone receptor 0.002 0.0002 0.0002
Trypanosoma cruzi histone deacetylase, putative 0.0257 0.1047 0.2008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.0748 0.1435
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.1127 0.4887 1
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0126 0.0469 0.0898
Echinococcus granulosus lamin dm0 0.0028 0.0036 0.0068
Echinococcus multilocularis acylamino acid releasing enzyme 0.0126 0.0469 0.0898
Plasmodium falciparum peptidase, putative 0.0126 0.0469 0.0941
Plasmodium falciparum importin beta, putative 0.003 0.0047 0.0077
Plasmodium falciparum histone deacetylase 1 0.0362 0.151 0.3076
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.0748 0.1435
Plasmodium vivax histone deacetylase, putative 0.0257 0.1047 0.2127
Echinococcus multilocularis calpain 7 (C02 family) 0.0057 0.0165 0.0316
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0024 0.0162
Schistosoma mansoni biogenic amine receptor 0.0044 0.0107 0.0107
Schistosoma mansoni ran 0.0022 0.0012 0.0012
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0312 0.1291 0.2172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0002 0.0003
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0035 0.0067 0.0111
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0855 0.3686 0.7073
Toxoplasma gondii aspartyl protease ASP3 0.0655 0.2805 0.5375
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0067 0.0113
Brugia malayi calpain family protein 1 0.0151 0.0582 0.0979
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0229 0.0385
Schistosoma mansoni hypothetical protein 0.004 0.009 0.009
Echinococcus multilocularis p2X purinoceptor 4 0.0072 0.0229 0.0438
Brugia malayi calpain family protein 1 0.0151 0.0582 0.0979
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Echinococcus granulosus neuropeptide FF receptor 2 0.0044 0.0107 0.0205
Loa Loa (eye worm) hypothetical protein 0.0134 0.0506 0.0851
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis inositol monophosphatase, putative 0.0075 0.0244 0.05
Trypanosoma brucei calpain-like protein, putative 0.0057 0.0165 0.0316
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0296 0.1219 0.2338
Brugia malayi RE15519p 0.0044 0.0107 0.018
Toxoplasma gondii histone deacetylase HDAC3 0.0362 0.151 0.2884
Onchocerca volvulus 0.0044 0.0107 0.0205
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0208 0.0398
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0099 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0002 0.0003
Brugia malayi KE2 family protein 0.0064 0.0193 0.0326
Echinococcus granulosus histone deacetylase 6 0.0257 0.1047 0.2009
Echinococcus multilocularis musashi 0.0028 0.0036 0.0067
Plasmodium falciparum plasmepsin VI 0.1127 0.4887 1
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0067 0.0111
Onchocerca volvulus Cathepsin L homolog 0.0025 0.0024 0.0047
Schistosoma mansoni hypothetical protein 0.0044 0.0107 0.0107
Brugia malayi G protein-coupled receptor F59B2.13 0.0044 0.0107 0.018
Echinococcus multilocularis enteropeptidase 0.004 0.009 0.0172
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis p2X purinoceptor 4 0.0072 0.0229 0.0438
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0067 0.0111
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.151 0.309
Giardia lamblia Histone deacetylase 0.0362 0.151 1
Brugia malayi aspartic protease BmAsp-1, identical 0.0312 0.1291 0.2172
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Brugia malayi Trypsin-like protease protein 5 0.004 0.009 0.0152
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Loa Loa (eye worm) proprotein convertase 2 0.0042 0.0099 0.0167
Plasmodium falciparum plasmepsin X 0.0655 0.2805 0.5732
Echinococcus granulosus neuropeptide receptor 0.0044 0.0107 0.0205
Entamoeba histolytica prolyl oligopeptidase family protein 0.0126 0.0469 0.3105
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0002 0.0003
Plasmodium falciparum prefoldin subunit 6, putative 0.0064 0.0193 0.0377
Schistosoma mansoni multidrug resistance protein 0.0022 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0044 0.0107 0.0107
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.0107 0.0204
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0241 0.0493
Schistosoma mansoni alpha-1 adrenergic receptor 0.0044 0.0107 0.0107
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0241 0.0241
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0477 0.202 1
Echinococcus granulosus G protein coupled receptor 139 0.0044 0.0107 0.0205
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.009 0.009
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.004 0.009 0.0172
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0074 0.0241 0.1188
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0015
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.001 0.002
Loa Loa (eye worm) aspartic protease BmAsp-2 0.1127 0.4887 0.8222
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0044 0.0107 0.0107
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0126 0.0469 0.0898
Onchocerca volvulus Histone deacetylase 10 homolog 0.013 0.0486 0.0932
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0042 0.0099 0.0191
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0241 0.0516
Onchocerca volvulus 0.0035 0.0067 0.0129
Trypanosoma brucei histone deacetylase, putative 0.0257 0.1047 0.2008
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.151 0.309
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0072 0.0139
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.0107 0.018
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0241 0.0405
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0002 0.0003
Echinococcus multilocularis membrane bound transcription factor site 1 0.0042 0.0099 0.0189
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0241 0.0516
Onchocerca volvulus 0.0025 0.0024 0.0047
Echinococcus granulosus calpain 0.0057 0.0165 0.0317
Echinococcus granulosus p2X purinoceptor 4 0.0072 0.0229 0.0439
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0072 0.0137
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.151 0.309
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0244 0.0467
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0126 0.0469 0.0469
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0196 0.0965
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni neuropeptide receptor 0.0044 0.0107 0.0107
Echinococcus multilocularis apoptotic protease activating factor 1 0.0134 0.0507 0.0971
Schistosoma mansoni P2X receptor subunit 0.0072 0.0229 0.0229
Giardia lamblia Cathepsin B precursor 0.0096 0.0337 0.2228
Plasmodium falciparum plasmepsin VIII, putative 0.0312 0.1291 0.2627
Leishmania major histone deacetylase, putative 0.0362 0.151 0.2897
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0002 0.0003
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0362 0.151 0.309
Onchocerca volvulus 0.0088 0.0301 0.0578
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.0107 0.0204
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Trypanosoma brucei calpain-like protein, putative 0.0057 0.0165 0.0316
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0241 0.0493
Echinococcus multilocularis calpain family protein 1, d 0.0112 0.0405 0.0777
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.0107 0.0205
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Mycobacterium ulcerans lipase LipD 0.0074 0.0241 0.1188
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0196 0.0965
Leishmania major GTP-binding protein, putative 0.0022 0.0012 0.0021
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Onchocerca volvulus 0.0035 0.0067 0.0129
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0002 0.0002
Echinococcus granulosus Dipeptidyl peptidase 9 0.0126 0.0469 0.09
Onchocerca volvulus 0.0025 0.0024 0.0047
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0901 0.0901
Brugia malayi Melatonin receptor type 1A 0.0044 0.0107 0.018
Toxoplasma gondii subtilisin SUB12 0.0077 0.0254 0.0469
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0474 0.2006 0.4308
Loa Loa (eye worm) hypothetical protein 0.0334 0.1387 0.2334
Leishmania major histone deacetylase, putative 0.0257 0.1047 0.2008
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0042 0.0099 0.0099
Schistosoma mansoni inhibitor of apoptosis protein 0.0334 0.1387 0.1387
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0126 0.0469 0.0959
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0162 0.0627 0.1202
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.0107 0.0204
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0025 0.0024 0.003
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0126 0.0469 0.3105
Echinococcus multilocularis importin subunit beta 1 0.003 0.0047 0.0089
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.0107 0.0107
Brugia malayi Matrixin family protein 0.015 0.0575 0.0967
Echinococcus multilocularis serotonin receptor 0.0044 0.0107 0.0204
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0072 0.0072
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Brugia malayi Trypsin family protein 0.004 0.009 0.0152
Loa Loa (eye worm) matrixin family protein 0.015 0.0575 0.0967
Brugia malayi calpain 5 0.0042 0.0099 0.0166
Echinococcus multilocularis dro:myosuppressin receptor 0.0044 0.0107 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0002 0.0003
Plasmodium falciparum plasmepsin VII 0.0312 0.1291 0.2627
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Leishmania major cathepsin L-like protease 0.0072 0.0233 0.0445
Toxoplasma gondii PAN/Apple domain-containing protein 0.0035 0.0067 0.0111
Toxoplasma gondii hypothetical protein 0.0126 0.0469 0.0882
Schistosoma mansoni P2X receptor subunit 0.0072 0.0229 0.0229
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.0107 0.0205
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0002 0.0002
Echinococcus granulosus g protein coupled receptor 0.0044 0.0107 0.0205
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Plasmodium vivax plasmepsin V, putative 0.0312 0.1291 0.2627
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Echinococcus granulosus neuropeptide receptor 0.0044 0.0107 0.0205
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0233 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Onchocerca volvulus Cathepsin F homolog 0.0025 0.0024 0.0047
Toxoplasma gondii subtilisin SUB10 0.0042 0.0099 0.0172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0002 0.0003
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Leishmania major p-glycoprotein 0.0022 0.001 0.0017
Trypanosoma brucei prolyl endopeptidase 0.12 0.5211 1
Echinococcus multilocularis prolyl endopeptidase 0.12 0.5211 1
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.004 0.009 0.0173
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0113
Echinococcus granulosus fmrfamide receptor 0.0044 0.0107 0.0205
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0078 0.0259 0.0259
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.117 0.117
Plasmodium vivax subtilisin-like serine protease, putative 0.0042 0.0099 0.0184
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Giardia lamblia Hypothetical protein 0.0064 0.0193 0.1277
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0244 0.0467
Loa Loa (eye worm) hypothetical protein 0.0285 0.117 0.1968
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0042 0.0099 0.0167
Onchocerca volvulus 0.0044 0.0107 0.0205
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0014 0.0025
Trypanosoma brucei kinesin, putative 0.004 0.009 0.017
Brugia malayi neuropeptide F receptor 0.0044 0.0107 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.0107 0.0205
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.1127 0.4887 0.9378
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0044 0.0107 0.0205
Schistosoma mansoni inositol monophosphatase 0.0075 0.0244 0.0244
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0042 0.0099 0.0167
Brugia malayi Serotonin receptor 0.0044 0.0107 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Echinococcus granulosus membrane bound transcription factor site 1 0.0042 0.0099 0.0191
Echinococcus granulosus neuroendocrine convertase 2 0.0042 0.0099 0.0191
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Echinococcus granulosus histone deacetylase 8 0.013 0.0486 0.0932
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Onchocerca volvulus 0.0094 0.033 0.0632
Plasmodium vivax histone deacetylase 2, putative 0.0257 0.1047 0.2127
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.0107 0.018
Entamoeba histolytica hypothetical protein 0.0025 0.0022 0.0145
Mycobacterium tuberculosis Probable peptidase 0.0477 0.202 0.4338
Leishmania major cysteine peptidase A (CPA) 0.0025 0.0024 0.0046
Echinococcus granulosus lamin 0.0028 0.0036 0.0068
Onchocerca volvulus 0.0074 0.0241 0.0462
Brugia malayi Cathepsin L-like precursor 0.0025 0.0024 0.0041
Brugia malayi ABC transporter family protein 0.0022 0.001 0.0016
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0137 0.0262
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0241 0.0516
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0405
Entamoeba histolytica hypothetical protein 0.0036 0.0072 0.0479
Brugia malayi putative neuropeptide receptor 0.0044 0.0107 0.018
Onchocerca volvulus 0.0044 0.0107 0.0205
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0012 0.0023
Leishmania major importin beta-1 subunit, putative 0.0025 0.0022 0.0041
Echinococcus multilocularis calpain 5 0.0059 0.0174 0.0333
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Onchocerca volvulus 0.0044 0.0107 0.0205
Schistosoma mansoni neuropeptide receptor 0.0044 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0025 0.0024 0.005
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0024 0.0024
Brugia malayi sulfakinin receptor protein 0.0044 0.0107 0.018
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0002 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0025 0.0024 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.0107 0.0205
Echinococcus multilocularis neuropeptide receptor A26 0.0044 0.0107 0.0204
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.0107 0.0107
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.0107 0.0204
Plasmodium vivax histone deacetylase, putative 0.013 0.0486 0.0976
Echinococcus multilocularis G protein coupled receptor 139 0.0044 0.0107 0.0204
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.001 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0067 0.0113
Trypanosoma cruzi prefoldin subunit, putative 0.0064 0.0193 0.037
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.0107 0.0205
Toxoplasma gondii subtilisin SUB7 0.0042 0.0099 0.0172
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Entamoeba histolytica hypothetical protein, conserved 0.0126 0.0469 0.3105
Brugia malayi beta-lactamase family protein 0.0074 0.0241 0.0405
Brugia malayi Matrixin family protein 0.0062 0.0187 0.0314
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Echinococcus multilocularis histone deacetylase 6 0.0257 0.1047 0.2008
Schistosoma mansoni opsin-like receptor 0.0044 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Leishmania major histone deacetylase, putative 0.0362 0.151 0.2897
Plasmodium vivax calpain, putative 0.0057 0.0165 0.0319
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Brugia malayi neuropeptide F receptor 0.0044 0.0107 0.018
Schistosoma mansoni calpain-7 (C02 family) 0.0057 0.0165 0.0165
Schistosoma mansoni biogenic amine receptor 0.0044 0.0107 0.0107
Leishmania major kinesin, putative 0.004 0.009 0.017
Onchocerca volvulus 0.0035 0.0067 0.0129
Brugia malayi Histone deacetylase family protein 0.0257 0.1047 0.1761
Schistosoma mansoni histone deacetylase hda2 0.0257 0.1047 0.1047
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0042 0.0099 0.0212
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.1345 0.2263
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0024 0.0162
Echinococcus multilocularis cathepsin b 0.0285 0.117 0.2244
Brugia malayi nuclear hormone receptor 0.002 0.0002 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0044 0.0107 0.018
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0241 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0193 0.0396
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0022 0.0045
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0241 0.0405
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0012 0.0004
Brugia malayi cathepsin B-like cysteine proteinase 0.0285 0.117 0.1968
Toxoplasma gondii microneme protein, putative 0.0035 0.0067 0.0111
Echinococcus multilocularis Mastin 0.004 0.009 0.0172
Brugia malayi calpain 7 0.0057 0.0165 0.0278
Onchocerca volvulus 0.0044 0.0107 0.0205
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Trypanosoma brucei calpain-like protein, putative 0.0057 0.0165 0.0316
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0225 0.0908 0.1743
Brugia malayi hypothetical protein 0.004 0.009 0.0152
Plasmodium vivax hypothetical protein, conserved 0.0126 0.0469 0.0941
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0042 0.0099 0.0212
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0126 0.0469 0.0469
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0002 0.0003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0002 0.0003
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0486 0.093
Entamoeba histolytica prolyl oligopeptidase family protein 0.0126 0.0469 0.3105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0002 0.0003
Onchocerca volvulus 0.0134 0.0507 0.0972
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0137 0.0262
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0241 0.0493
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0434 0.073
Schistosoma mansoni amine GPCR 0.0044 0.0107 0.0107
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0162 0.0627 0.1201
Entamoeba histolytica calpain large subunit domain III containing protein 0.004 0.009 0.0593
Trypanosoma brucei prolyl oligopeptidase, putative 0.0477 0.202 0.3875
Echinococcus granulosus prefoldin subunit 6 0.0064 0.0193 0.0371
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.001 0.0017
Leishmania major cathepsin L-like protease 0.0025 0.0024 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0002 0.0003
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0044 0.0107 0.0107
Toxoplasma gondii microneme protein MIC17C 0.0035 0.0067 0.0111
Echinococcus granulosus 7tm_1 domain containing protein 0.0044 0.0107 0.0205
Echinococcus multilocularis neuroendocrine convertase 2 0.0042 0.0099 0.0189
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0042 0.0099 0.0212
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0126 0.0469 0.09
Echinococcus granulosus allatostatin A receptor 0.0044 0.0107 0.0205
Echinococcus granulosus peptide allatostatin:somatostatin 0.0044 0.0107 0.0205
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.1483 0.2496
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.001 0.0065
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0196 0.0419
Toxoplasma gondii histone deacetylase HDAC1 0.0257 0.1047 0.1994
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0126 0.0469 0.0898
Echinococcus multilocularis histone deacetylase 6 0.0257 0.1047 0.2008
Echinococcus granulosus prolyl endopeptidase 0.12 0.5211 1
Brugia malayi Cathepsin L-like precursor 0.0025 0.0024 0.0041
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0076 0.0246 0.0528
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.002
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0096 0.0337 0.0645
Schistosoma mansoni hypothetical protein 0.0167 0.0649 0.0649
Echinococcus granulosus cathepsin L cysteine proteinase 0.0025 0.0024 0.0047
Toxoplasma gondii microneme protein MIC17B 0.0035 0.0067 0.0111
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0137 0.0261
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.1483 0.2845
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Brugia malayi GnHR receptor homolog 0.0044 0.0107 0.018
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0126 0.0469 0.0469
Loa Loa (eye worm) hypothetical protein 0.0126 0.0469 0.0789
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0044 0.0107 0.018
Brugia malayi Hemopexin family protein 0.0088 0.0301 0.0507
Onchocerca volvulus 0.0184 0.0724 0.139
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0002 0.0003
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0036 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0017
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0126 0.0469 0.0469
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0196 0.0374
Mycobacterium leprae Probable lipase LipE 0.0074 0.0241 0.0736
Brugia malayi histone deacetylase 11 0.013 0.0486 0.0817
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0405
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.0107 0.0204
Echinococcus granulosus acylamino acid releasing enzyme 0.0126 0.0469 0.09
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0025 0.0024 0.003
Brugia malayi beta-lactamase 0.0074 0.0241 0.0405
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0044 0.0107 0.0204
Onchocerca volvulus 0.0035 0.0067 0.0129
Schistosoma mansoni coup transcription factor 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0044 0.0107 0.0205
Loa Loa (eye worm) cathepsin B 0.0096 0.0337 0.0567
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0107 0.0107
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0126 0.0469 0.09
Schistosoma mansoni hypothetical protein 0.0134 0.0507 0.0507
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.0107 0.0107
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Echinococcus multilocularis allatostatin A receptor 0.0044 0.0107 0.0204
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0477 0.202 0.4338
Brugia malayi hypothetical protein 0.0312 0.1291 0.2172
Echinococcus granulosus snurportin 1 0.0324 0.1345 0.2582
Schistosoma mansoni hypothetical protein 0.0167 0.0649 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Toxoplasma gondii subtilisin SUB4 0.0042 0.0099 0.0172
Brugia malayi Serotonin receptor 0.0044 0.0107 0.018
Schistosoma mansoni neuropeptide f receptor 76f 0.0044 0.0107 0.0107
Toxoplasma gondii subtilisin SUB11 0.0042 0.0099 0.0172
Brugia malayi Histone deacetylase family protein 0.0257 0.1047 0.1761
Plasmodium vivax vivapain-2 0.0025 0.0024 0.003
Toxoplasma gondii aspartyl protease ASP1 0.1127 0.4887 0.9377
Onchocerca volvulus 0.0224 0.0901 0.173
Schistosoma mansoni histone deacetylase 1 2 3 0.013 0.0486 0.0486
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0012 0.002
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0042 0.0099 0.0488
Echinococcus granulosus neuropeptide receptor A26 0.0044 0.0107 0.0205
Echinococcus granulosus histone deacetylase 0.0257 0.1047 0.2009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0044 0.0107 0.018
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0434 0.073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.0107 0.018
Toxoplasma gondii subtilisin SUB2 0.0042 0.0099 0.0172
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0225 0.0908 0.1741
Echinococcus granulosus inositol monophosphatase 1 0.0075 0.0244 0.0469
Onchocerca volvulus Deterin homolog 0.0334 0.1387 0.2662
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0002 0.0003
Leishmania major oligopeptidase b 0.0477 0.202 0.3875
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.002
Trypanosoma cruzi kinesin, putative 0.004 0.009 0.017
Onchocerca volvulus 0.0022 0.001 0.0019
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Brugia malayi Cathepsin L-like precursor 0.0025 0.0024 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Echinococcus granulosus histone deacetylase 6 0.0257 0.1047 0.2009
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0075 0.0244 0.5
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.12 0.5211 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.0107 0.0204
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0196 0.0374
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0126 0.0469 0.3105
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.009 0.009
Plasmodium falciparum plasmepsin III 0.0312 0.1291 0.2627
Schistosoma mansoni hypothetical protein 0.0324 0.1345 0.1345
Plasmodium vivax importin-beta 2, putative 0.003 0.0047 0.0077
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0044 0.0107 0.0107
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0012 0.0021
Echinococcus multilocularis histone deacetylase 8 0.013 0.0486 0.093
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0062 0.0187 0.0187
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0012 0.002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0022 0.0045
Schistosoma mansoni histone deacetylase 0.0362 0.151 0.151
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0067 0.0111
Loa Loa (eye worm) inositol-1 0.0075 0.0244 0.0411
Trichomonas vaginalis taga, putative 0.0022 0.001 0.002
Echinococcus granulosus enteropeptidase 0.004 0.009 0.0173
Leishmania major hypothetical protein, conserved 0.0078 0.0259 0.0496
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0405
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0486 0.093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Brugia malayi proprotein convertase 2 0.0042 0.0099 0.0167
Echinococcus granulosus FTZ F1 alpha 0.002 0.0002 0.0003
Toxoplasma gondii histone deacetylase HDAC4 0.013 0.0486 0.0915
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0362 0.151 0.309
Onchocerca volvulus 0.0044 0.0107 0.0205
Leishmania major cathepsin L-like protease 0.0025 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Schistosoma mansoni caspase-7 (C14 family) 0.0153 0.0589 0.0589
Brugia malayi G-protein coupled receptor 0.0044 0.0107 0.018
Schistosoma mansoni memapsin-2 (A01 family) 0.0312 0.1291 0.1291
Trypanosoma brucei histone deacetylase 2 0.013 0.0486 0.093
Schistosoma mansoni calpain (C02 family) 0.0057 0.0165 0.0165
Onchocerca volvulus 0.0044 0.0107 0.0205
Trichomonas vaginalis abcb9, putative 0.0022 0.001 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Toxoplasma gondii aspartyl protease 0.0312 0.1291 0.2463
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0241 0.1188
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0044 0.0107 0.0107
Brugia malayi Trypsin family protein 0.004 0.009 0.0152
Onchocerca volvulus 0.0035 0.0067 0.0129
Toxoplasma gondii histone deacetylase HDAC2 0.0362 0.151 0.2884
Plasmodium vivax subtilisin-like protease 1 0.0042 0.0099 0.0184
Brugia malayi G-protein coupled receptor 0.0044 0.0107 0.018
Echinococcus granulosus tissue type plasminogen activator 0.0078 0.0259 0.0497
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0002 0.0002
Echinococcus multilocularis prefoldin subunit 6 0.0064 0.0193 0.037
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0057 0.0165 0.0316
Echinococcus multilocularis cathepsin L cysteine protease 0.0025 0.0024 0.0046
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Echinococcus multilocularis snurportin 1 0.0324 0.1345 0.258
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0312 0.1291 0.2172
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0047 0.0089
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.001 0.0019
Schistosoma mansoni hypothetical protein 0.0044 0.0107 0.0107
Echinococcus granulosus serotonin receptor 0.0044 0.0107 0.0205
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0044 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Toxoplasma gondii subtilisin SUB1 0.0042 0.0099 0.0172
Echinococcus granulosus cathepsin b 0.0285 0.117 0.2245
Brugia malayi Cathepsin L-like precursor 0.0025 0.0024 0.0041
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0017
Echinococcus granulosus histone deacetylase 1 0.0362 0.151 0.2898
Mycobacterium ulcerans hypothetical protein 0.009 0.031 0.1532
Mycobacterium tuberculosis Conserved protein 0.0074 0.0241 0.0516
Plasmodium falciparum subtilisin-like protease 1 0.0042 0.0099 0.0184
Plasmodium falciparum subtilisin-like protease 2 0.0042 0.0099 0.0184
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0362 0.151 0.309
Loa Loa (eye worm) hypothetical protein 0.0127 0.0474 0.0798
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0477 0.202 1
Onchocerca volvulus 0.0028 0.0036 0.0068
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.001 0.0065
Brugia malayi hypothetical protein 0.0051 0.0137 0.0231
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0137 0.0245
Toxoplasma gondii PAN domain-containing protein 0.0326 0.1351 0.2579
Echinococcus multilocularis histone deacetylase 3 0.0362 0.151 0.2897
Onchocerca volvulus 0.0044 0.0107 0.0205
Loa Loa (eye worm) hypothetical protein 0.0127 0.0474 0.0798
Onchocerca volvulus 0.0334 0.1387 0.2662
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.151 0.309
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0126 0.0469 0.0959
Echinococcus multilocularis calpain A 0.0162 0.0628 0.1203
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0057 0.0165 0.0316
Trypanosoma cruzi histone deacetylase 1, putative 0.0362 0.151 0.2897
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Echinococcus multilocularis g-protein coupled receptor 0.0044 0.0107 0.0204
Echinococcus multilocularis sex peptide receptor 0.0044 0.0107 0.0204
Echinococcus granulosus intermediate filament protein 0.0028 0.0036 0.0068
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.0107 0.0107
Schistosoma mansoni amine GPCR 0.0044 0.0107 0.0107
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0002 0.0002
Schistosoma mansoni ran 0.0022 0.0012 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0096 0.0337 0.0337
Trypanosoma cruzi kinesin, putative 0.004 0.009 0.017
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0078 0.0259 0.0511
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0162 0.0627 0.0627
Loa Loa (eye worm) melatonin receptor type 1A 0.0044 0.0107 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0233 0.0445
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0477 0.202 0.3875
Brugia malayi Pepsin A precursor 0.0312 0.1291 0.2172
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0107 0.0205
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0312 0.1291 0.2463
Schistosoma mansoni inositol monophosphatase 0.0075 0.0244 0.0244
Entamoeba histolytica cysteine protease, putative 0.0025 0.0024 0.0162
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0312 0.1291 0.1291
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0229 0.0439
Loa Loa (eye worm) prolyl oligopeptidase 0.0126 0.0469 0.0789
Echinococcus granulosus histone deacetylase 7 0.0257 0.1047 0.2009
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0025 0.0024 0.0041
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0126 0.0469 0.0898
Echinococcus multilocularis cathepsin L cysteine protease 0.0025 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0064 0.0193 0.0326
Trichomonas vaginalis abcb9, putative 0.0022 0.001 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.0107 0.0205
Onchocerca volvulus 0.0044 0.0107 0.0205
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0057 0.0165 0.0316
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0002 0.0003
Schistosoma mansoni amine GPCR 0.0044 0.0107 0.0107
Loa Loa (eye worm) prolyl oligopeptidase 0.0126 0.0469 0.0789
Schistosoma mansoni thyroid hormone receptor 0.002 0.0002 0.0002
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0012 0.0004
Brugia malayi prolyl oligopeptidase family protein 0.0126 0.0469 0.0789
Entamoeba histolytica prefoldin subunit 6, putative 0.0064 0.0193 0.1281
Schistosoma mansoni histamine h1 receptor 0.0044 0.0107 0.0107
Schistosoma mansoni Mername-AA248 (C02 family) 0.0059 0.0174 0.0174
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.0748 0.1436
Plasmodium falciparum cysteine proteinase falcipain 3 0.0025 0.0024 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Echinococcus granulosus Furin 1 0.0042 0.0099 0.0191
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.001 0.0017
Brugia malayi Trypsin family protein 0.004 0.009 0.0152
Loa Loa (eye worm) hypothetical protein 0.0062 0.0187 0.0314
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0002 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0189 0.0748 0.1259
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0022 0.001 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0107 0.0204
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0296 0.1219 0.2339
Brugia malayi histone deacetylase 3 (HD3) 0.0362 0.151 0.254
Onchocerca volvulus 0.0078 0.0259 0.0497
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.0107 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0203
Toxoplasma gondii subtilisin SUB8 0.0042 0.0099 0.0172
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0025 0.0024 0.0046
Schistosoma mansoni biogenic amine receptor 0.0044 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0044 0.0107 0.018
Trypanosoma brucei histone deacetylase 1 0.0362 0.151 0.2897
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0012 0.0021
Onchocerca volvulus 0.0312 0.1291 0.2477
Brugia malayi PAN domain containing protein 0.0035 0.0067 0.0113
Schistosoma mansoni gabp alpha 0.0072 0.0229 0.0229
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0067 0.021 0.0574
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0241 0.0462
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.117 0.117
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.009 0.009
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.002
Brugia malayi hypothetical protein 0.0312 0.1291 0.2172
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0044 0.0107 0.0205
Brugia malayi MH2 domain containing protein 0.0118 0.0434 0.073
Echinococcus multilocularis g protein coupled receptor 0.0044 0.0107 0.0204
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.009 0.009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0099 0.0203
Loa Loa (eye worm) hypothetical protein 0.0126 0.0469 0.0789
Schistosoma mansoni myosin xvIII 0.0044 0.0107 0.0107
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0241 0.0493
Schistosoma mansoni ets-related 0.0217 0.0872 0.0872
Echinococcus granulosus alpha 1A adrenergic receptor 0.0044 0.0107 0.0205
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.0107 0.0204
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0241 0.0474
Entamoeba histolytica P-glycoprotein-1 0.0022 0.001 0.0065
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0137 0.0262
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0196 0.0965
Brugia malayi hypothetical protein 0.0044 0.0107 0.018
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Brugia malayi prolyl oligopeptidase family protein 0.0126 0.0469 0.0789
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.1127 0.4887 0.9378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0024 0.005
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.12 0.5211 0.5211
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Onchocerca volvulus 0.0035 0.0067 0.0129
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0012 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0203
Toxoplasma gondii cathepsin CPL 0.0025 0.0024 0.0028
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0107 0.018
Echinococcus granulosus somatostatin receptor 0.0044 0.0107 0.0205
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0024 0.005
Schistosoma mansoni neuropeptide receptor 0.0044 0.0107 0.0107
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0042 0.0099 0.0189

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 327 uM Inhibitory activity against Human immunodeficiency virus-1 protease ChEMBL. 15261290
IC50 (binding) = 327 uM Inhibitory activity against Human immunodeficiency virus-1 protease ChEMBL. 15261290
Ki (binding) = 199 uM Binding activity towards Human immunodeficiency virus-1 protease ChEMBL. 15261290
Ki (binding) = 199 uM Binding activity towards Human immunodeficiency virus-1 protease ChEMBL. 15261290

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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