Detailed information for compound 331980

Basic information

Technical information
  • TDR Targets ID: 331980
  • Name: methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-furan-3 -yl-6a,10b-dimethyl-4,10-dioxo-9-(2,2,2-trich loroethanimidoyl)oxy-2,4a,5,6,7,8,9,10a-octah ydro-1H-benzo[f]isochromene-7-carboxylate
  • MW: 534.814 | Formula: C23H26Cl3NO7
  • H donors: 0 H acceptors: 3 LogP: 4.46 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)[C@@H]1C[C@H](OC(=N)C(Cl)(Cl)Cl)C(=O)[C@H]2[C@@]1(C)CC[C@@H]1[C@]2(C)C[C@H](OC1=O)c1cocc1
  • InChi: 1S/C23H26Cl3NO7/c1-21-6-4-12-19(30)33-15(11-5-7-32-10-11)9-22(12,2)17(21)16(28)14(8-13(21)18(29)31-3)34-20(27)23(24,25)26/h5,7,10,12-15,17,27H,4,6,8-9H2,1-3H3/t12-,13-,14-,15-,17-,21-,22-/m0/s1
  • InChiKey: SWEVIHKTFQZWOP-XOKLNVNFSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxo-9-(2,2,2-trichloroethanimidoyl)oxy-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
  • (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxo-9-(2,2,2-trichloro-1-iminoethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylic acid methyl ester
  • (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-furyl)-4,10-diketo-6a,10b-dimethyl-9-(2,2,2-trichloroacetimidoyl)oxy-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylic acid methyl ester
  • methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-furan-3-yl-6a,10b-dimethyl-4,10-dioxo-9-(2,2,2-trichloroethanimidoyloxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens opioid receptor, mu 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, kappa 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, delta 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0177 0.0393 0.5602
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0099 0.0211 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0209 0.297
Echinococcus multilocularis protein patched 0.0083 0.0176 0.0176
Entamoeba histolytica protein kinase, putative 0.0177 0.0393 0.6604
Echinococcus granulosus g protein coupled receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0128 0.0279 0.0279
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Entamoeba histolytica cell division protein kinase 2, putative 0.0043 0.0081 0.134
Entamoeba histolytica histone deacetylase, putative 0.0263 0.0594 1
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0249
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0232 0.3296
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0088 0.1262
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Leishmania major hypothetical protein, conserved 0.0029 0.0049 0.0672
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) RecQ helicase 0.002 0.0027 0.0385
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0029 0.0049 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0033 0.0443
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0005 0.0003
Brugia malayi nuclear receptor RXR 0.001 0.0003 0.0046
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0099 0.0211 0.0211
Chlamydia trachomatis dehyroquinate synthase 0.0232 0.0522 0.0617
Echinococcus granulosus fmrfamide receptor 0.0009 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0025 0.0369
Schistosoma mansoni cell adhesion molecule 0.0015 0.0017 0.0017
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0102 0.0219 0.3135
Echinococcus granulosus hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0029 0.0049 0.0049
Echinococcus multilocularis cpg binding protein 0.003 0.0051 0.0051
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0146 0.206
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0078 0.0163 0.0394
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0027 0.0027
Brugia malayi hypothetical protein 0.0119 0.0259 0.3503
Brugia malayi Carboxylesterase family protein 0.0066 0.0135 0.1827
Trichomonas vaginalis rotamase, putative 0.0034 0.0059 0.094
Onchocerca volvulus 0.0099 0.0211 0.3974
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0028 0.0381
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0058 0.0795
Brugia malayi Protein kinase domain containing protein 0.0128 0.0279 0.3763
Loa Loa (eye worm) hypothetical protein 0.0053 0.0104 0.1489
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0009 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0029 0.0049 0.0769
Schistosoma mansoni histone deacetylase 0.0263 0.0594 0.0594
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0029 0.0049 0.0049
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0263 0.0594 0.9703
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0099 0.0211 0.0211
Toxoplasma gondii histone deacetylase HDAC3 0.0263 0.0594 0.0734
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0001 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0146 0.0303
Onchocerca volvulus 0.0099 0.0211 0.3974
Brugia malayi hypothetical protein 0.0128 0.0279 0.3763
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0634 0.1457 0.1457
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.0687 0.9821
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0071 0.0086
Schistosoma mansoni opsin-like receptor 0.0009 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase pr2 0.0029 0.0049 0.0049
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0232 0.3316
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0049 0.0769
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0194 0.0434 0.6205
Brugia malayi G protein-coupled receptor F59B2.13 0.0009 0.0001 0.0017
Toxoplasma gondii histone deacetylase HDAC1 0.0308 0.0699 0.0866
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0099 0.0211 0.3974
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0117 0.0117
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0029 0.0049 0.0049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0099 0.0211 0.3974
Loa Loa (eye worm) hypothetical protein 0.0071 0.0146 0.2084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Onchocerca volvulus 0.0098 0.021 0.3961
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0009 0.0001 0.0018
Trypanosoma cruzi histone deacetylase, putative 0.0308 0.0699 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0135 0.0135
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.003 0.0028
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.003 0.0393
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0049 0.0049
Schistosoma mansoni BC026374 protein (S09 family) 0.0011 0.0007 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0028 0.0028
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.008 0.127
Brugia malayi Tyrosine-protein kinase PR2 0.0029 0.0049 0.0661
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0594 0.9703
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0066 0.0066
Echinococcus multilocularis activated cdc42 kinase 1 0.0029 0.0049 0.0049
Schistosoma mansoni alpha-1 adrenergic receptor 0.0009 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0001 0.0001
Schistosoma mansoni flap endonuclease-1 0.0023 0.0035 0.0035
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.003 0.0464
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0041 0.0048
Echinococcus granulosus sex peptide receptor 0.0009 0.0001 0.0001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0049 0.0028
Brugia malayi protein C24B5.3 0.0012 0.0009 0.0117
Onchocerca volvulus 0.0071 0.0146 0.2737
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0001 0.0001
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0232 0.0522 0.1301
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0029 0.0049 0.0661
Loa Loa (eye worm) hypothetical protein 0.0175 0.039 0.557
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0009 0.0001 0.0018
Loa Loa (eye worm) histone methyltransferase 0.001 0.0004 0.0059
Brugia malayi tailless protein 0.001 0.0003 0.0046
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Echinococcus multilocularis alkaline phosphatase 0.0161 0.0356 0.0356
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0017 0.022
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0029 0.0049 0.07
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Brugia malayi nuclear hormone receptor 0.002 0.0028 0.0381
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0161 0.0356 0.0356
Onchocerca volvulus 0.0029 0.0049 0.0903
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0099 0.0211 0.0211
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0009 0.0001 0.0001
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Brugia malayi Sex muscle abnormal protein 5 0.0099 0.0211 0.2849
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0128 0.0279 0.0279
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni importin beta-1 0.0028 0.0047 0.0047
Trypanosoma brucei histone deacetylase 1 0.0263 0.0594 0.8483
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0047 0.0673
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0594 0.9703
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0065
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0027 0.003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni histamine h1 receptor 0.0009 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0009 0.0001 0.0001
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Loa Loa (eye worm) hypothetical protein 0.0098 0.021 0.3007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) TK/INSR protein kinase 0.0029 0.0049 0.07
Schistosoma mansoni hypothetical protein 0.0035 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0027 0.0413
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0104 0.0097
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Echinococcus multilocularis cyclin dependent kinase 1 0.0043 0.0081 0.0081
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0029 0.0049 0.0661
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0043 0.0081 0.1136
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0111 0.1567
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.003 0.045
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.003 0.0028
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0027 0.0364
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0028 0.0028
Brugia malayi Patched protein homolog 1 0.0012 0.0009 0.0117
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0003 0.0003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0062 0.0062
Onchocerca volvulus 0.0021 0.003 0.0535
Loa Loa (eye worm) TK/EPH protein kinase 0.0029 0.0049 0.07
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0128 0.0279 0.4676
Trypanosoma brucei unspecified product 0.0091 0.0194 0.2752
Schistosoma mansoni DNA helicase recq1 0.002 0.0027 0.0027
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.003 0.0056
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0177 0.0393 0.6604
Loa Loa (eye worm) hypothetical protein 0.015 0.033 0.4715
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.4204 0.977 0.977
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0017 0.0017
Echinococcus granulosus histone deacetylase 6 0.0308 0.0699 0.0699
Loa Loa (eye worm) TK protein kinase 0.0128 0.0279 0.3985
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Plasmodium falciparum chorismate synthase 0.3469 0.8059 1
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0029 0.0049 0.0672
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0066 0.0066
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Onchocerca volvulus 0.0128 0.0279 0.5257
Echinococcus multilocularis raf serine:threonine protein kinase 0.0029 0.0049 0.0049
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Schistosoma mansoni apoptosis regulator bax 0.0082 0.0172 0.0172
Onchocerca volvulus Tyrosine kinase homolog 0.0029 0.0049 0.0903
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0027 0.0027
Onchocerca volvulus 0.0128 0.0279 0.5257
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0041 0.0557
Echinococcus multilocularis activin receptor type 0.003 0.0052 0.0052
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0005 0.0035
Brugia malayi Protein kinase domain containing protein 0.0177 0.0393 0.5303
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0017 0.0019
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Loa Loa (eye worm) hypothetical protein 0.0053 0.0104 0.1489
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Echinococcus granulosus neuropeptide receptor 0.0009 0.0001 0.0001
Brugia malayi SH2 domain containing protein 0.0128 0.0279 0.3763
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0015 0.0017 0.0017
Echinococcus granulosus cyclin dependent kinase 1 0.0043 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Onchocerca volvulus 0.0029 0.0049 0.0903
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Echinococcus multilocularis histone deacetylase 8 0.013 0.0284 0.0284
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0008
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0043 0.0081 0.1136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0009 0.0001 0.0001
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.025 0.0562 0.0562
Schistosoma mansoni vesicular amine transporter 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis N chimaerin 0.0099 0.0211 0.0211
Entamoeba histolytica protein kinase domain containing protein 0.0177 0.0393 0.6604
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0128 0.0279 0.0279
Onchocerca volvulus 0.003 0.0052 0.0952
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0232 0.3316
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0027 0.042
Echinococcus granulosus tyrosine protein kinase Src42A 0.0128 0.0279 0.0279
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0058 0.0795
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0039 0.053
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0029 0.0049 0.0049
Brugia malayi hypothetical protein 0.0099 0.0211 0.2849
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0117 0.0117
Echinococcus granulosus expressed conserved protein 0.0183 0.0407 0.0407
Toxoplasma gondii exonuclease III APE 0.0019 0.0025 0.0028
Echinococcus granulosus acetylcholinesterase 0.0066 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus multilocularis natriuretic peptide receptor 1 0.0029 0.0049 0.0049
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0001 0.0001
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0029 0.0049 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0209 0.297
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0029 0.0049 0.0769
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.003 0.0056
Echinococcus granulosus neuropeptide FF receptor 2 0.0009 0.0001 0.0001
Loa Loa (eye worm) TK/CSK protein kinase 0.0029 0.0049 0.07
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0066 0.1048
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0211 0.2849
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0028 0.0403
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0029 0.0049 0.07
Loa Loa (eye worm) hypothetical protein 0.0263 0.0594 0.8488
Schistosoma mansoni thyroid hormone receptor 0.002 0.0028 0.0028
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus granulosus histone deacetylase 3 0.0263 0.0594 0.0594
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0005 0.0042
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0027 0.003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0028 0.0028
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0059 0.0849
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.003 0.0399
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Trichomonas vaginalis TK family protein kinase 0.0029 0.0049 0.0769
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0049 0.0792
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0047 0.0649
Leishmania major histone deacetylase, putative 0.0308 0.0699 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0088 0.0088
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0161 0.0356 0.0356
Onchocerca volvulus 0.0019 0.0027 0.0478
Brugia malayi Protein kinase domain containing protein 0.0128 0.0279 0.3763
Brugia malayi Patched related family protein 12 0.0012 0.0009 0.0117
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Echinococcus multilocularis tensin 0.0099 0.0211 0.0211
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Leishmania major hypothetical protein, conserved 0.0016 0.0017 0.022
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0099 0.0211 0.0211
Echinococcus granulosus integrin linked protein kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni hypothetical protein 0.0403 0.0919 0.0919
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0066 0.0917
Echinococcus granulosus tyrosine protein kinase Src42A 0.0099 0.0211 0.0211
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0002 0.003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0009 0.0001 0.0001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0028 0.0028
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0001 0.0018
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0009 0.0001 0.0018
Schistosoma mansoni opsin-like receptor 0.0009 0.0001 0.0001
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0009 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.0207 0.0463 0.6248
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0041 0.0557
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0001 0.0001
Brugia malayi hypothetical protein 0.001 0.0003 0.0046
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0017 0.0017
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0072 0.0148 0.2114
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Plasmodium vivax chorismate synthase 0.3469 0.8059 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0128 0.0279 0.0279
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.035
Echinococcus multilocularis cyclin dependent kinase 0.0043 0.0081 0.0081
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0232 0.2757
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Brugia malayi topoisomerase 0.0019 0.0027 0.0358
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0111 0.1567
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0146 0.0172
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0124
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0049 0.0028
Schistosoma mansoni amine GPCR 0.0009 0.0001 0.0001
Loa Loa (eye worm) carboxylesterase 0.0066 0.0135 0.1935
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.008 0.0096
Schistosoma mansoni rotamase 0.0034 0.0059 0.0059
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Echinococcus multilocularis FL cytokine receptor 0.0029 0.0049 0.0049
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0008
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Brugia malayi RE15519p 0.0009 0.0001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Loa Loa (eye worm) TK/FAK protein kinase 0.0029 0.0049 0.07
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0029 0.0049 0.0049
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.003 0.0393
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0364 0.083 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.003 0.0035
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0049 0.0049
Schistosoma mansoni tyrosine kinase 0.0128 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0049 0.0769
Brugia malayi putative neuropeptide receptor NPR1 0.0009 0.0001 0.0017
Entamoeba histolytica recQ family helicase, putative 0.001 0.0004 0.0026
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi conserved hypotetical protein 0.001 0.0003 0.0046
Plasmodium vivax histone deacetylase, putative 0.0308 0.0699 0.0866
Echinococcus granulosus histone deacetylase 6 0.0308 0.0699 0.0699
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis SH2 motif 0.0099 0.0211 0.0211
Brugia malayi hypothetical protein 0.001 0.0003 0.0046
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0009 0.0001 0.0017
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0146 0.035
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0065
Brugia malayi Raf kinase 0.0029 0.0049 0.0661
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0043 0.0081 0.1163
Schistosoma mansoni hypothetical protein 0.008 0.0169 0.0169
Loa Loa (eye worm) TK/ALK protein kinase 0.0029 0.0049 0.07
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0232 0.377
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Brugia malayi G-protein coupled receptor 0.0009 0.0001 0.0017
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0257 0.3669
Echinococcus multilocularis tyrosine protein kinase Abl 0.0128 0.0279 0.0279
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0066 0.1048
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0211 0.0211
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0001 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0209 0.0251
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0017 0.0017
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0017 0.0017
Schistosoma mansoni glutaminase 0.0271 0.0612 0.0612
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0029 0.0049 0.0792
Plasmodium vivax histone deacetylase 1, putative 0.0263 0.0594 0.0734
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Brugia malayi Histone deacetylase 1 0.0263 0.0594 0.8016
Loa Loa (eye worm) histone deacetylase 1 0.0263 0.0594 0.8488
Leishmania major hypothetical protein, conserved 0.0025 0.0039 0.053
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0177 0.0393 0.5615
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0028 0.0381
Loa Loa (eye worm) STAT protein 0.0099 0.0211 0.3017
Echinococcus granulosus serotonin receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0052 0.0052
Brugia malayi MH2 domain containing protein 0.0118 0.0257 0.3465
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0052 0.0052
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0003 0.0046
Echinococcus multilocularis tyrosine protein kinase Blk 0.0128 0.0279 0.0279
Echinococcus granulosus natriuretic peptide receptor 1 0.0029 0.0049 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0028 0.0403
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0003 0.0003
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) hypothetical protein 0.0257 0.058 0.8287
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0066 0.0066
Echinococcus multilocularis neuroglian 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0379
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Plasmodium vivax tyrosine kinase-like protein, putative 0.0029 0.0049 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0027 0.0031
Onchocerca volvulus 0.0099 0.0211 0.3974
Echinococcus granulosus neuroligin 0.0011 0.0007 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Echinococcus multilocularis 0.0099 0.0211 0.0211
Schistosoma mansoni hypothetical protein 0.008 0.0169 0.0169
Brugia malayi RhoGAP domain containing protein 0.0099 0.0211 0.2849
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0027 0.035
Schistosoma mansoni growth factor receptor-bound protein 0.0099 0.0211 0.0211
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0104 0.012
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0216 0.2918
Echinococcus granulosus G protein coupled receptor 139 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni biogenic amine receptor 0.0009 0.0001 0.0001
Echinococcus granulosus cyclin dependent kinase 5 0.0043 0.0081 0.0081
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0025 0.0028
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0028 0.0403
Loa Loa (eye worm) hypothetical protein 0.0066 0.0135 0.1935
Brugia malayi larval opioid receptor 0.0009 0.0001 0.0017
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0001 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.0009 0.0001 0.0001
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0211 0.2849
Loa Loa (eye worm) glutaminase 0.0271 0.0612 0.8746
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0379
Loa Loa (eye worm) hypothetical protein 0.0082 0.0172 0.2462
Onchocerca volvulus 0.0021 0.003 0.0535
Brugia malayi hypothetical protein 0.015 0.033 0.4453
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus multilocularis allatostatin A receptor 0.0009 0.0001 0.0001
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.003 0.003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.003 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Schistosoma mansoni neuroligin 3 (S09 family) 0.0011 0.0007 0.0007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0124 0.1776
Echinococcus granulosus tyrosine protein kinase HCK 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0019 0.0027 0.0261
Toxoplasma gondii propionate-CoA ligase 0.0021 0.003 0.0034
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0025 0.0381
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0263 0.0594 0.9703
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Plasmodium falciparum protein kinase, putative 0.0029 0.0049 0.0058
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0052 0.0846
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0123 0.0123
Echinococcus multilocularis histone deacetylase 6 0.0308 0.0699 0.0699
Echinococcus multilocularis orexin receptor type 2 0.0009 0.0001 0.0001
Schistosoma mansoni topbp1 0.0019 0.0027 0.0027
Echinococcus granulosus histone deacetylase 6 0.0314 0.0714 0.0714
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.003 0.003
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0146 0.2428
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0027 0.0408
Echinococcus granulosus SH2 domain containing protein 7 0.0099 0.0211 0.0211
Schistosoma mansoni histone deacetylase 4 5 0.0308 0.0699 0.0699
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0028 0.0403
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Entamoeba histolytica SH2-protein kinase domain containing protein 0.01 0.0214 0.3585
Echinococcus multilocularis dual specificity testis specific protein kinase 0.003 0.0052 0.0052
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0194 0.0434 0.7302
Echinococcus granulosus raf serine:threonine protein kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0119 0.0259 0.371
Brugia malayi hypothetical protein 0.0029 0.0049 0.0661
Echinococcus multilocularis histone deacetylase 6 0.0314 0.0714 0.0714
Echinococcus multilocularis tumor protein p63 0.0672 0.1546 0.1546
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0001 0.0001
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0211 0.0211
Loa Loa (eye worm) SRC-1 0.0128 0.0279 0.3985
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0081 0.0081
Plasmodium falciparum protein kinase 5 0.0043 0.0081 0.0098
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0101 0.0216 0.3089
Schistosoma mansoni nuclear hormone receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0379
Schistosoma mansoni growth factor receptor-bound protein 0.0099 0.0211 0.0211
Echinococcus granulosus orexin receptor type 2 0.0009 0.0001 0.0001
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0049 0.0903
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Onchocerca volvulus 0.0012 0.0009 0.014
Echinococcus granulosus dual specificity 0.0177 0.0393 0.0393
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0052 0.0717
Onchocerca volvulus 0.0029 0.0049 0.0903
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0029 0.0049 0.0049
Brugia malayi ephrin receptor 1 precursor 0.0029 0.0049 0.0661
Echinococcus multilocularis signal transduction protein lnk realted 0.0099 0.0211 0.0211
Schistosoma mansoni alkaline phosphatase 0.0161 0.0356 0.0356
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0128 0.0279 0.0279
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0099 0.0211 0.3017
Onchocerca volvulus 0.0012 0.0009 0.014
Loa Loa (eye worm) hypothetical protein 0.025 0.0562 0.8041
Brugia malayi GnHR receptor homolog 0.0009 0.0001 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0003 0.0003
Echinococcus granulosus SH2 domain containing adapter protein F 0.0099 0.0211 0.0211
Schistosoma mansoni 3-dehydroquinate synthase 0.0232 0.0522 0.0522
Brugia malayi ecdysteroid receptor 0.002 0.0028 0.0381
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0099 0.0211 0.0211
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0007 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0097 0.0228
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.0919 0.0919
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Plasmodium vivax protein kinase, putative 0.0029 0.0049 0.0058
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0027 0.0027
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0099 0.0211 0.3017
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0146 0.1968
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.009 0.1286
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0197 0.0441 0.0441
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0028 0.051
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.003 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0058 0.0795
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0066 0.0066
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0049 0.0049
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0121 0.0121
Entamoeba histolytica SH2 domain containing protein 0.0099 0.0211 0.3531
Trichomonas vaginalis protein tyrosine kinase, putative 0.0029 0.0049 0.0769
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0017 0.0249
Echinococcus granulosus allatostatin A receptor 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0012 0.0009 0.014
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0047 0.0056
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Trichomonas vaginalis glutaminase, putative 0.0271 0.0612 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0006 0.0086
Schistosoma mansoni hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Echinococcus granulosus activated cdc42 kinase 1 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni cpg binding protein 0.003 0.0051 0.0051
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0028 0.0028
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0001 0.0001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0025 0.0381
Schistosoma mansoni neuropeptide receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis NCK adaptor protein 0.0099 0.0211 0.0211
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0004 0.0002
Trichomonas vaginalis STE family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) serine/threonine protein kinase 0.0029 0.0049 0.07
Brugia malayi jmjC domain containing protein 0.0016 0.0017 0.0235
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0002 0.0028
Loa Loa (eye worm) protein kinase domain-containing protein 0.0029 0.0049 0.07
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Brugia malayi STAT protein, DNA binding domain containing protein 0.0099 0.0211 0.2849
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0146 0.0172
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0033 0.0443
Echinococcus granulosus neuropeptide receptor 0.0009 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) histone deacetylase 11 0.013 0.0284 0.4056
Giardia lamblia Kinase, NEK 0.0029 0.0049 0.0792
Echinococcus granulosus epidermal growth factor receptor 0.0029 0.0049 0.0049
Entamoeba histolytica recQ family DNA helicase 0.001 0.0005 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0401
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0232 0.0522
Brugia malayi hypothetical protein 0.0012 0.0009 0.0117
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0009 0.0001 0.0001
Echinococcus granulosus tar DNA binding protein 0.0061 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0677
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.008 0.008
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0002 0.0002
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0029 0.0049 0.0049
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Echinococcus multilocularis Niemann Pick C1 protein 0.0194 0.0434 0.0434
Schistosoma mansoni biogenic amine receptor 0.0009 0.0001 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0249
Echinococcus granulosus suppressor of cytokine signaling 7 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Schistosoma mansoni ap endonuclease 0.0019 0.0025 0.0025
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0232 0.0232
Onchocerca volvulus 0.0012 0.0009 0.014
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0146 0.1968
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.0004 0.0002
Loa Loa (eye worm) carboxylesterase 0.0011 0.0007 0.0104
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.003 0.0035
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.003 0.0399
Echinococcus granulosus tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Brugia malayi hypothetical protein 0.0019 0.0027 0.0358
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0006 0.0006
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0017 0.0017
Echinococcus granulosus somatostatin receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0029 0.0049 0.0049
Trypanosoma cruzi cdc2-related kinase 3 0.0043 0.0081 0.1136
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0049 0.0769
Schistosoma mansoni biogenic amine receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0249
Plasmodium vivax histone deacetylase, putative 0.013 0.0284 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0176 0.2845
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0082
Schistosoma mansoni ran 0.0021 0.003 0.003
Brugia malayi polk-prov protein 0.0049 0.0094 0.1273
Schistosoma mansoni amine GPCR 0.0009 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.4303 1 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0128 0.0279 0.0279
Echinococcus multilocularis GPCR, family 2 0.0047 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0003 0.0048
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0029 0.0049 0.07
Echinococcus granulosus kinase suppressor of Ras 1 0.0029 0.0049 0.0049
Echinococcus multilocularis growth factor receptor bound protein 2 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0128 0.0279 0.0279
Schistosoma mansoni histone deacetylase 4 5 0.0308 0.0699 0.0699
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0041 0.0585
Echinococcus multilocularis tensin 0.0099 0.0211 0.0211
Echinococcus multilocularis dna polymerase eta 0.0097 0.0207 0.0207
Onchocerca volvulus 0.0011 0.0007 0.0113
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0003 0.004
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0017 0.0017
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Brugia malayi ORL1-like opioid receptor 0.0009 0.0001 0.0017
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0004 0.0004
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0029 0.0049 0.0049
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.003 0.0393
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Leishmania major histone deacetylase, putative 0.0308 0.0699 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0029 0.0049 0.0661
Plasmodium falciparum DNA repair protein REV1, putative 0.0022 0.0033 0.0038
Toxoplasma gondii histone deacetylase HDAC4 0.013 0.0284 0.035
Echinococcus granulosus tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0027 0.0356
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.0422
Plasmodium vivax DNA repair protein REV1, putative 0.0022 0.0033 0.0038
Toxoplasma gondii histone deacetylase HDAC5 0.013 0.0284 0.035
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Leishmania major DNA polymerase kappa, putative 0.0078 0.0163 0.2309
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0028 0.0381
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0049 0.0058
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0211 0.2849
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0325 0.4644
Brugia malayi protein-tyrosine kinase 0.0128 0.0279 0.3763
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0097 0.0228
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0029 0.0049 0.0903
Schistosoma mansoni hypothetical protein 0.0084 0.0176 0.0176
Trypanosoma brucei cdc2-related kinase 3 0.0043 0.0081 0.1136
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Brugia malayi ecdysone receptor 0.001 0.0003 0.0046
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0009 0.0001 0.0018
Brugia malayi Carboxylesterase family protein 0.0066 0.0135 0.1827
Onchocerca volvulus 0.0128 0.0279 0.5257
Schistosoma mansoni patched 1 0.0083 0.0176 0.0176
Echinococcus granulosus expressed conserved protein 0.0099 0.0211 0.0211
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis ephrin type A receptor 4 A 0.0029 0.0049 0.0049
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0066 0.0066
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Schistosoma mansoni amine GPCR 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0049 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus granulosus importin subunit beta 1 0.0028 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Entamoeba histolytica receptor protein kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica ankyrin repeat protein 0.0029 0.0049 0.0792
Toxoplasma gondii protein kinase domain-containing protein 0.0029 0.0049 0.0058
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0029 0.0049 0.0049
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0002 0.0028
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0003 0.0003
Echinococcus multilocularis protein KINase family member (kin 25) 0.0029 0.0049 0.0049
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.003 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0028 0.0381
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0049 0.0049
Trypanosoma brucei DNA polymerase eta, putative 0.0097 0.0207 0.2933
Loa Loa (eye worm) hypothetical protein 0.0138 0.0303 0.4328
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus granulosus tyrosine kinase 0.0128 0.0279 0.0279
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0082 0.0172 0.0172
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0027 0.0401
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0049 0.0049
Echinococcus granulosus defective proboscis extension response 0.0015 0.0017 0.0017
Trypanosoma cruzi cdc2-related kinase 3 0.0043 0.0081 0.1136
Brugia malayi TAR-binding protein 0.0061 0.0124 0.1678
Schistosoma mansoni tyrosine kinase 0.0128 0.0279 0.0279
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Schistosoma mansoni hypothetical protein 0.0011 0.0007 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Schistosoma mansoni histone deacetylase 0.0263 0.0594 0.0594
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0028 0.0028
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0017 0.0017
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0003 0.0003
Echinococcus multilocularis protein dispatched 1 0.0095 0.0203 0.0203
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Echinococcus granulosus cpg binding protein 0.003 0.0051 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0135 0.1935
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0124
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0025 0.0243
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0029 0.0049 0.0049
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0027 0.0024
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0072 0.0148 0.0148
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0004 0.0004
Echinococcus granulosus histone deacetylase 1 0.0263 0.0594 0.0594
Leishmania major importin beta-1 subunit, putative 0.0023 0.0035 0.047
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Schistosoma mansoni tensin 0.0099 0.0211 0.0211
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0062 0.0062
Schistosoma mansoni ephrin receptor 0.0029 0.0049 0.0049
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0028 0.0381
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0177 0.0393 0.5602
Schistosoma mansoni suppressor of cytokine signaling 0.0099 0.0211 0.0211
Entamoeba histolytica hypothetical protein 0.0023 0.0035 0.0554
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.003 0.0034
Schistosoma mansoni amine GPCR 0.0009 0.0001 0.0001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0009 0.0001 0.0001
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.008 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0029 0.0049 0.0903
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0028 0.051
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Brugia malayi hypothetical protein 0.0012 0.0009 0.0117
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0028 0.0028
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0072 0.0148 0.0148
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0003 0.0046
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0569 0.1306 0.1306
Echinococcus multilocularis muscleblind protein 1 0.0295 0.0668 0.0668
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0009 0.0001 0.0017
Leishmania major DNA damage repair protein, putative 0.0022 0.0033 0.0443
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0029 0.0049 0.0661
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Schistosoma mansoni hypothetical protein 0.0099 0.0211 0.0211
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0257 0.3669
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0006 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0002 0.0002
Trichomonas vaginalis ran, putative 0.0021 0.003 0.0456
Schistosoma mansoni neuropeptide receptor 0.0009 0.0001 0.0001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0009 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0049 0.0049
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni DNA helicase recq5 0.002 0.0027 0.0027
Onchocerca volvulus 0.002 0.0028 0.051
Schistosoma mansoni terminal deoxycytidyl transferase 0.0072 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0128 0.0279 0.3985
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0047 0.0649
Schistosoma mansoni hypothetical protein 0.0099 0.0211 0.0211
Brugia malayi histone deacetylase 11 0.013 0.0284 0.383
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0072 0.0148 0.0148
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.003 0.0056
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0035 0.047
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0049 0.0661
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0041 0.0657
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.003 0.0393
Loa Loa (eye worm) hypothetical protein 0.0042 0.0078 0.1118
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0025 0.0323
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0029 0.0049 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Schistosoma mansoni protein kinase 0.003 0.0052 0.0052
Leishmania major histone deacetylase, putative 0.0263 0.0594 0.8483
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0066 0.0917
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0232 0.3885
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Brugia malayi Carboxylesterase family protein 0.0011 0.0007 0.0098
Echinococcus granulosus epidermal growth factor receptor 0.0029 0.0049 0.0049
Onchocerca volvulus 0.0011 0.0007 0.0113
Loa Loa (eye worm) SH2 domain-containing protein 0.0099 0.0211 0.3017
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0284 0.4038
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0081 0.13
Brugia malayi 6-phosphofructokinase 0.0108 0.0232 0.3132
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0596 0.137 0.1673
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.003 0.0422
Brugia malayi Carboxylesterase family protein 0.0011 0.0007 0.0098
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0049 0.07
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0104 0.0245
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0097 0.0228
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0017 0.0223
Echinococcus multilocularis tyrosine protein kinase HCK 0.0029 0.0049 0.0049
Echinococcus multilocularis BC026374 protein (S09 family) 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0009 0.0001 0.0017
Echinococcus granulosus dro:myosuppressin receptor 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0235 0.0529 1
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0001 0.0001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0049 0.0058
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0007 0.0007
Brugia malayi nuclear receptor NHR-88 0.002 0.0028 0.0381
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0049 0.0769
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0003 0.0046
Echinococcus multilocularis G protein coupled receptor 139 0.0009 0.0001 0.0001
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.003 0.0399
Toxoplasma gondii STE kinase 0.0029 0.0049 0.0058
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.003 0.0028
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0029 0.0049 0.0049
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0027 0.0364
Echinococcus multilocularis Immunoglobulin 0.0015 0.0017 0.0017
Plasmodium falciparum importin beta, putative 0.0028 0.0047 0.0056
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.003 0.045
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus granulosus suppressor of cytokine signaling 6 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.0422
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0099 0.0211 0.0211
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0078 0.0163 0.2309
Brugia malayi Nuclear hormone receptor E75 0.001 0.0003 0.0046
Brugia malayi AKH receptor 0.0009 0.0001 0.0017
Echinococcus granulosus alkaline phosphatase 0.0161 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0029 0.0049 0.07
Trypanosoma brucei Pseudokinase, putative 0.0029 0.0049 0.0672
Echinococcus granulosus cyclin dependent kinase 0.0043 0.0081 0.0081
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0009 0.0001 0.0001
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.0048 0.0057
Plasmodium falciparum protein kinase, putative 0.0029 0.0049 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0049 0.0769
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) acetyltransferase 0.0144 0.0316 0.4511
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0066 0.1048
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0049 0.0792
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0161 0.0356 0.0356
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0049 0.0058
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0124
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0529 0.8643
Brugia malayi putative neuropeptide receptor 0.0009 0.0001 0.0017
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.009 0.009
Plasmodium falciparum tyrosine kinase-like protein 0.0029 0.0049 0.0058
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0029 0.0049 0.0049
Chlamydia trachomatis chorismate synthase 0.3469 0.8059 1
Entamoeba histolytica cell division protein kinase 2, putative 0.0043 0.0081 0.134
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0099 0.0211 0.3017
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0099 0.0211 0.3017
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0027 0.035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0028 0.0381
Echinococcus multilocularis tyrosine kinase 0.0128 0.0279 0.0279
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0025 0.0323
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.1286
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0364 0.083 0.1021
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0003 0.0046
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0052 0.0717
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0043 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0086
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0146 0.0172
Echinococcus multilocularis serotonin receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0007 0.0007
Brugia malayi hypothetical protein 0.0012 0.0009 0.0117
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Echinococcus multilocularis SH2 motif 0.0099 0.0211 0.0211
Echinococcus granulosus SHC transforming protein 3 0.0099 0.0211 0.0211
Trichomonas vaginalis protein kinase atn1, putative 0.0029 0.0049 0.0769
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0097 0.0228
Loa Loa (eye worm) hypothetical protein 0.0148 0.0325 0.4644
Echinococcus multilocularis g-protein coupled receptor 0.0009 0.0001 0.0001
Brugia malayi CXXC zinc finger family protein 0.0028 0.0047 0.0636
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0088 0.0088
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0232 0.3885
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0124
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0146 0.2428
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Onchocerca volvulus 0.015 0.033 0.6224
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0594 0.9703
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Schistosoma mansoni hypothetical protein 0.0082 0.0172 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi Protein kinase domain containing protein 0.0128 0.0279 0.3763
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0099 0.0211 0.3017
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0124 0.1678
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.003 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0393 0.0393
Trichomonas vaginalis DNA polymerase eta, putative 0.0098 0.0209 0.3397
Plasmodium vivax protein kinase Crk2 0.0043 0.0081 0.0098
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0001 0.0001
Echinococcus granulosus SH2 motif 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0944
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.003 0.0393
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0027 0.0401
Giardia lamblia DINP protein human, muc B family 0.0078 0.0163 0.2722
Entamoeba histolytica Ran family GTPase 0.0021 0.003 0.047
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0025 0.0332
Echinococcus granulosus Protein patched homolog 1 0.0083 0.0176 0.0176
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0001 0.0001
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0028 0.0028
Brugia malayi hypothetical protein 0.0025 0.0039 0.0527
Brugia malayi CHE-14 protein 0.0083 0.0176 0.237
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0083 0.0176 0.251
Schistosoma mansoni coup transcription factor 0.002 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) hypothetical protein 0.0069 0.0142 0.2027
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.003 0.0422
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0001 0.0018
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0028 0.0028
Echinococcus multilocularis dual specificity 0.0177 0.0393 0.0393
Schistosoma mansoni histone deacetylase hda2 0.0314 0.0714 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0059 0.094
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0044 0.0084 0.1205
Brugia malayi jmjC domain containing protein 0.006 0.0121 0.1629
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0049 0.0792
Echinococcus granulosus BC026374 protein S09 family 0.0011 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0596 0.137 0.1693
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0049 0.07
Echinococcus granulosus microtubule associated protein 2 0.1363 0.3155 0.3155
Leishmania major DNA polymerase kappa, putative 0.0022 0.0033 0.0443
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0086
Loa Loa (eye worm) melatonin receptor type 1A 0.0009 0.0001 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Brugia malayi C-terminal src kinase protein 1 0.0029 0.0049 0.0661
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0128 0.0279 0.0279
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Schistosoma mansoni hypothetical protein 0.0101 0.0216 0.0216
Schistosoma mansoni thyroid hormone receptor 0.002 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.008 0.127
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0146 0.0172
Brugia malayi G-protein coupled receptor 0.0009 0.0001 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0002 0.0002
Giardia lamblia Protein 21.1 0.0029 0.0049 0.0792
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0177 0.0393 0.5602
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0003 0.0003
Loa Loa (eye worm) TK/EGFR protein kinase 0.0029 0.0049 0.07
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.0427
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0058 0.0795
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0025 0.0369
Brugia malayi sulfakinin receptor protein 0.0009 0.0001 0.0017
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0033 0.0038
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0088 0.1192
Schistosoma mansoni tensin 0.0099 0.0211 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0094 0.1322
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.003 0.003
Schistosoma mansoni tensin 0.0099 0.0211 0.0211
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0017 0.0017
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0232 0.0232
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0028 0.0028
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0028 0.0028
Schistosoma mansoni zinc finger protein 0.001 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Toxoplasma gondii hypothetical protein 0.0012 0.0009 0.0008
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Brugia malayi nuclear receptor NHR-88 0.001 0.0003 0.0046
Echinococcus granulosus c src tyrosine kinase 0.0128 0.0279 0.0279
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0316 0.0316
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0027 0.003
Echinococcus multilocularis epidermal growth factor receptor 0.0029 0.0049 0.0049
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0009 0.0001 0.0001
Leishmania major histone deacetylase, putative 0.0263 0.0594 0.8483
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0002 0.0028
Echinococcus granulosus protein tyrosine kinase 0.0029 0.0049 0.0049
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0041 0.0048
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0005 0.0003
Echinococcus granulosus bloom syndrome protein 0.002 0.0027 0.0027
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0463 0.6615
Trypanosoma cruzi protein kinase, putative 0.0029 0.0049 0.0672
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0002 0.003
Onchocerca volvulus 0.0099 0.0211 0.3974
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.047
Onchocerca volvulus 0.0012 0.0009 0.014
Echinococcus multilocularis histone deacetylase 0.0308 0.0699 0.0699
Echinococcus granulosus tyrosine kinase 0.0128 0.0279 0.0279
Loa Loa (eye worm) TK/ACK protein kinase 0.0029 0.0049 0.07
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0043 0.0081 0.1163
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Plasmodium vivax SET domain protein, putative 0.003 0.0052 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0028 0.0403
Plasmodium falciparum tyrosine kinase-like protein 0.0029 0.0049 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0027 0.0364
Onchocerca volvulus 0.001 0.0003 0.004
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0028 0.0381
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0111 0.1567
Loa Loa (eye worm) hypothetical protein 0.0071 0.0146 0.2084
Echinococcus granulosus acetylcholinesterase 0.0066 0.0135 0.0135
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0099 0.0211 0.3017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.003 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0028 0.0381
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.0404
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0047 0.0047
Brugia malayi neuropeptide F receptor 0.0009 0.0001 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0119 0.0259 0.371
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Plasmodium vivax importin-beta 2, putative 0.0028 0.0047 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Brugia malayi phosphofructokinase 0.0108 0.0232 0.3132
Schistosoma mansoni hypothetical protein 0.008 0.0169 0.0169
Schistosoma mansoni alkaline phosphatase 0.0161 0.0356 0.0356
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0009 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0232 0.3296
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0185 0.0411 0.5876
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0081 0.0081
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0001 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0066 0.0891
Brugia malayi G protein-coupled receptor 0.0009 0.0001 0.0017
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0017 0.022
Schistosoma mansoni DNA polymerase eta 0.0097 0.0207 0.0207
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0049 0.07
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Brugia malayi 6-phosphofructokinase 0.0108 0.0232 0.3134
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1602 0.3711 0.3711
Onchocerca volvulus Protein patched homolog 0.0012 0.0009 0.014
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0008
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0035 0.0537
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Brugia malayi hypothetical protein 0.0012 0.0009 0.0117
Loa Loa (eye worm) hypothetical protein 0.013 0.0284 0.4056
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Echinococcus granulosus neuropeptide s receptor 0.0009 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi Patched related family protein 10 0.0012 0.0009 0.0117
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0232 0.0522 0.1258
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0033 0.0443
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0009 0.0001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Loa Loa (eye worm) DR-78 0.001 0.0003 0.0048
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0003 0.0003
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Echinococcus granulosus peptide allatostatin:somatostatin 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0209 0.297
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0028 0.0028
Giardia lamblia Kinase, CMGC CDK 0.0043 0.0081 0.134
Plasmodium falciparum histone deacetylase 2 0.0308 0.0699 0.0866
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0066 0.0066
Echinococcus multilocularis kinase suppressor of Ras 1 0.0029 0.0049 0.0049
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0033 0.0443
Echinococcus granulosus dna polymerase eta 0.0097 0.0207 0.0207
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0232 0.0279
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0124
Brugia malayi DKFZp564C0469 protein 0.0019 0.0027 0.0358
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus multilocularis muscleblind protein 0.0295 0.0668 0.0668
Echinococcus multilocularis transfer RNA-Thr 0.0029 0.0049 0.0049
Loa Loa (eye worm) oxidoreductase 0.0021 0.003 0.0422
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Onchocerca volvulus 0.0021 0.003 0.0535
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0058 0.0937
Giardia lamblia DNA damage repair protein 0.0022 0.0033 0.0522
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0135 0.0135
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.003 0.0008
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.003 0.0034
Mycobacterium ulcerans glutaminase 0.0271 0.0612 0.0751
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.003 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis bloom syndrome protein 0.002 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi AMP-binding enzyme family protein 0.0021 0.003 0.0399
Brugia malayi hypothetical protein 0.0011 0.0006 0.0082
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0029 0.0049 0.0049
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0049 0.0049
Trypanosoma cruzi DNA polymerase eta, putative 0.0097 0.0207 0.2933
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0135 0.0135
Brugia malayi Tensin 0.0099 0.0211 0.2849
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0025 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0003 0.004
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.003 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Brugia malayi Histone deacetylase family protein 0.0308 0.0699 0.9445
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0027 0.0401
Echinococcus multilocularis expressed conserved protein 0.0183 0.0407 0.0407
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0146 0.035
Loa Loa (eye worm) hypothetical protein 0.0295 0.0668 0.9554
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0117 0.0142
Echinococcus granulosus GPCR family 2 0.0047 0.009 0.009
Echinococcus granulosus tensin 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0175 0.039 0.557
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0025 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0099 0.0211 0.0211
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0029 0.0049 0.0049
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0027 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0017 0.0249
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0004 0.0052
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Loa Loa (eye worm) TK/ROR protein kinase 0.0029 0.0049 0.07
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0009 0.0001 0.0001
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0049 0.0049
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0263 0.0594 0.9703
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0049 0.0539
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.003 0.0052 0.0062
Brugia malayi hypothetical protein 0.0035 0.0062 0.0843
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Brugia malayi jmjC domain containing protein 0.0058 0.0117 0.1578
Schistosoma mansoni serine/threonine RGC 0.0029 0.0049 0.0049
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.0148 0.1997
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0009 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0027 0.0408
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0325 0.4386
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0009 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0128 0.0279 0.5257
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0049 0.0049
Brugia malayi Histone deacetylase family protein 0.0308 0.0699 0.9445
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0594 0.9703
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0003 0.0003
Brugia malayi nuclear receptor RXR 0.0011 0.0006 0.0082
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0027 0.0358
Brugia malayi neuropeptide F receptor 0.0009 0.0001 0.0017
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0316 0.4261
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0049 0.0049
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0041 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Entamoeba histolytica hypothetical protein 0.0019 0.0027 0.0413
Brugia malayi hypothetical protein 0.0029 0.0049 0.0661
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0028 0.0028
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0029 0.0049 0.0058
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0002 0.003
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Brugia malayi steroid hormone receptor 0.002 0.0028 0.0381
Brugia malayi hypothetical protein 0.0016 0.0019 0.025
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0124
Brugia malayi Melatonin receptor type 1A 0.0009 0.0001 0.0017
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.003 0.0028
Entamoeba histolytica ankyrin repeat protein 0.0029 0.0049 0.0792
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0001 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0316 0.0316
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0146 0.0303
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni ephrin receptor 0.0029 0.0049 0.0049
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0379
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0099 0.0211 0.0211
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0088 0.0088
Echinococcus multilocularis somatostatin receptor 0.0009 0.0001 0.0001
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0232 0.0522 0.1301
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Onchocerca volvulus 0.0029 0.0049 0.0903
Echinococcus multilocularis histone deacetylase 1 0.0263 0.0594 0.0594
Brugia malayi ImpB/MucB/SamB family protein 0.0097 0.0207 0.279
Loa Loa (eye worm) histone deacetylase 3 0.0263 0.0594 0.8488
Echinococcus granulosus neuroglian 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0401
Brugia malayi Latrophilin receptor protein 2 0.0047 0.009 0.1214
Schistosoma mansoni hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni tyrosine protein kinase 0.0029 0.0049 0.0049
Schistosoma mansoni myosin xvIII 0.0009 0.0001 0.0001
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0071 0.1171
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0027 0.0408
Echinococcus granulosus histone deacetylase 8 0.013 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0027 0.0401
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0401
Echinococcus multilocularis neuroligin 0.0011 0.0007 0.0007
Echinococcus granulosus insulin receptor 0.0029 0.0049 0.0049
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0596 0.137 0.3412
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0049 0.0769
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0001 0.0001
Echinococcus granulosus activated cdc42 kinase 1 0.0029 0.0049 0.0049
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0027 0.0413
Plasmodium falciparum flap endonuclease 1 0.0026 0.0041 0.0048
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0128 0.0279 0.0279
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0043 0.0081 0.0098
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0209 0.297
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0028 0.0381
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi bone morphogenetic protein type 1 receptor 0.0029 0.0049 0.0661
Loa Loa (eye worm) SH2 domain-containing protein 0.0099 0.0211 0.3017
Schistosoma mansoni nuclear receptor 0.001 0.0003 0.0003
Schistosoma mansoni signal transduction protein lnk-related 0.0099 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.0558
Loa Loa (eye worm) TYRA-2 protein 0.0009 0.0001 0.0018
Brugia malayi Protein kinase domain containing protein 0.0043 0.0081 0.1098
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0017 0.0017
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0025 0.0323
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0029 0.0049 0.0792
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0099 0.0211 0.0211
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0009 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0009 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica protein kinase, putative 0.01 0.0214 0.3585
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0008
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0029 0.0049 0.0058
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0027 0.0356
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0003 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0028 0.0403
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0325 0.4386
Echinococcus granulosus signal transduction protein lnk realted 0.0099 0.0211 0.0211
Echinococcus granulosus muscleblind protein 0.0295 0.0668 0.0668
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0099 0.0211 0.0211
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0284 0.4038
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Brugia malayi Serotonin receptor 0.0009 0.0001 0.0017
Echinococcus granulosus ephrin type A receptor 4 A 0.0029 0.0049 0.0049
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0007 0.0007
Schistosoma mansoni gliotactin 0.0011 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0401
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0025 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0052 0.0052
Echinococcus granulosus g protein coupled receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0052 0.0737
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0082
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Brugia malayi RNA binding protein 0.0061 0.0124 0.1678
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0002 0.003
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0029 0.0049 0.0049
Brugia malayi Dopamine receptor 0.0009 0.0001 0.0017
Echinococcus multilocularis SH2 motif 0.0099 0.0211 0.0211
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0017 0.022
Schistosoma mansoni tensin-related 0.0099 0.0211 0.0211
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0005 0.0004
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0232 0.0522 0.0639
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.003 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0163 0.2309
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0385
Echinococcus granulosus tumor protein p63 0.0672 0.1546 0.1546
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0232 0.0232
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0104 0.0127
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Brugia malayi Nuclear hormone receptor E75 0.001 0.0003 0.0046
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0124
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0177 0.0393 0.5602
Brugia malayi histone deacetylase 1 (HD1) 0.0263 0.0594 0.8016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Brugia malayi hypothetical protein 0.0019 0.0027 0.0358
Schistosoma mansoni opsin-like receptor 0.0009 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Echinococcus multilocularis SHC transforming protein 3 0.0099 0.0211 0.0211
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0041 0.0637
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0124
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0027 0.0385
Giardia lamblia Histone deacetylase 0.0263 0.0594 1
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0049 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0232 0.377
Schistosoma mansoni histone deacetylase hda2 0.013 0.0284 0.0284
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.102
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0049 0.0661
Loa Loa (eye worm) TK/Met protein kinase 0.0029 0.0049 0.07
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0028 0.0381
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) hypothetical protein 0.0097 0.0207 0.2954
Echinococcus multilocularis dna polymerase kappa 0.0098 0.0209 0.0209
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0005 0.0042
Brugia malayi jmjC domain containing protein 0.0016 0.0017 0.0235
Trypanosoma brucei protein kinase, putative 0.003 0.0052 0.0717
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0003 0.0003
Schistosoma mansoni adenoreceptor 0.0009 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0049 0.0049
Onchocerca volvulus 0.0029 0.0049 0.0903
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0029 0.0049 0.0769
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Schistosoma mansoni vav2 0.0099 0.0211 0.0211
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni hypothetical protein 0.0303 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Echinococcus granulosus Niemann Pick C1 protein 0.0278 0.0628 0.0628
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0021 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Echinococcus multilocularis Immunoglobulin 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0179 0.0397 0.5676
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0005 0.0042
Echinococcus multilocularis heat shock protein 70 0.0029 0.0049 0.0049
Onchocerca volvulus 0.0029 0.0049 0.0903
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis neuropeptide receptor A26 0.0009 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Schistosoma mansoni neuropeptide f receptor 76f 0.0009 0.0001 0.0001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0146 0.0172
Echinococcus granulosus alpha 1A adrenergic receptor 0.0009 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0128 0.0279 0.3763
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0082 0.0172 0.2326
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.025 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.003 0.0399
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0364 0.083 1
Trypanosoma brucei chrX additional, unordered contigs 0.0022 0.0033 0.0443
Echinococcus multilocularis tyrosine protein kinase shark 0.4303 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0029 0.0049 0.0661
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0092 0.0111
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0049 0.0792
Plasmodium vivax JmjC domain containing protein 0.0016 0.0017 0.0019
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0027 0.003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0028 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0121 0.1725
Toxoplasma gondii histone deacetylase HDAC2 0.0263 0.0594 0.0734
Schistosoma mansoni SH2A 0.0099 0.0211 0.0211
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Brugia malayi hypothetical protein 0.0011 0.0007 0.0098
Echinococcus multilocularis snurportin 1 0.0303 0.0687 0.0687
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0041 0.0557
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0135 0.0135
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0099 0.0211 0.0211
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0128 0.0279 0.0279
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.003 0.0393
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0379
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0028 0.0381
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0098 0.0209 0.3397
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.003 0.003
Loa Loa (eye worm) TK protein kinase 0.0029 0.0049 0.07
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0128 0.0279 0.0279
Echinococcus multilocularis nibrin 0.0019 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0009 0.0001 0.0001
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.003 0.0028
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0035 0.0537
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0128 0.0279 0.0279
Echinococcus granulosus tyrosine protein kinase Blk 0.0128 0.0279 0.0279
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Brugia malayi jmjC domain containing protein 0.0016 0.0017 0.0235
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0326 0.0741 1
Echinococcus multilocularis epidermal growth factor receptor 0.0029 0.0049 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) histone deacetylase 0.0308 0.0699 1
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0039 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0209 0.297
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0027 0.0401
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0028 0.0403
Echinococcus multilocularis tyrosine protein kinase pr2 0.0029 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0084 0.1138
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.003 0.0393
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Brugia malayi AMP-binding enzyme family protein 0.0021 0.003 0.0399
Loa Loa (eye worm) TK/RYK protein kinase 0.0029 0.0049 0.07
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.021 0.021
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0035 0.0537
Echinococcus granulosus tyrosine protein kinase Lyn 0.0129 0.0282 0.0282
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0209 0.0251
Brugia malayi SRC-1 0.0128 0.0279 0.3763
Echinococcus multilocularis para nitrobenzyl esterase 0.0011 0.0007 0.0007
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0029 0.0049 0.0049
Echinococcus granulosus histone deacetylase 0.0308 0.0699 0.0699
Brugia malayi Pre-SET motif family protein 0.003 0.0052 0.0696
Echinococcus multilocularis neuropeptide s receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0279 0.3985
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0028 0.0028
Trypanosoma cruzi histone deacetylase 1, putative 0.0263 0.0594 0.8483
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0161 0.0356 0.0356
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0039 0.0046
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0099 0.0211 0.0211
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Plasmodium falciparum histone deacetylase, putative 0.0308 0.0699 0.0866
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0146 0.1968
Trypanosoma cruzi protein kinase, putative 0.0029 0.0049 0.0672
Mycobacterium ulcerans hypothetical protein 0.0071 0.0146 0.0172
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Brugia malayi jmjC domain containing protein 0.0016 0.0017 0.0235
Echinococcus multilocularis expressed protein 0.0034 0.0059 0.0059
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) glutaminase 2 0.0271 0.0612 0.8746
Trypanosoma brucei histone deacetylase 3 0.0308 0.0699 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.003 0.0399
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0029 0.0049 0.0769
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0003 0.0003
Brugia malayi Tachykinin-like peptides receptor 99D 0.0009 0.0001 0.0017
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0009 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0021 0.003 0.0399
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus granulosus flap endonuclease 1 0.0026 0.0041 0.0041
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0043 0.0081 0.1163
Echinococcus granulosus FTZ F1 alpha 0.002 0.0028 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0081 0.13
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Echinococcus granulosus protein kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) histone deacetylase 7A 0.0308 0.0699 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis serotonin receptor 0.0009 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.009 0.1214
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis protein kinase 0.0029 0.0049 0.0049
Echinococcus granulosus Niemann Pick C1 protein 0.0194 0.0434 0.0434
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0025 0.0022
Onchocerca volvulus 0.0011 0.0007 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0232 0.377
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0029 0.0049 0.07
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis protein tyrosine kinase 0.0029 0.0049 0.0049
Brugia malayi follicle stimulating hormone receptor 0.0009 0.0001 0.0017
Echinococcus multilocularis tyrosine protein kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0002 0.0002
Schistosoma mansoni shc transforming protein 0.0099 0.0211 0.0211
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0161 0.0356 0.0356
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0033 0.0443
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0306 0.0306
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0058 0.0069
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0049 0.0769
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0028 0.0381
Toxoplasma gondii protein kinase 0.0029 0.0049 0.0058
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0028 0.0381
Treponema pallidum DNA ligase (lig) 0.0019 0.0027 0.0266
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0011 0.0007 0.0085
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0039 0.0046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0027 0.0027
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0015 0.0017 0.0017
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.008 0.0096
Loa Loa (eye worm) hypothetical protein 0.0053 0.0104 0.1489
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Onchocerca volvulus Histone deacetylase 10 homolog 0.013 0.0284 0.5351
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0128 0.0279 0.0279
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0048 0.0048
Onchocerca volvulus 0.0029 0.0049 0.0903
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Entamoeba histolytica recQ family helicase, putative 0.002 0.0027 0.042
Trypanosoma brucei histone deacetylase 2 0.013 0.0284 0.4038
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0027 0.0356
Entamoeba histolytica protein kinase, putative 0.0177 0.0393 0.6604
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus granulosus expressed protein 0.0034 0.0059 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0088 0.0088
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni cpg binding protein 0.0028 0.0047 0.0047
Loa Loa (eye worm) carboxylesterase 0.0011 0.0007 0.0104
Loa Loa (eye worm) SH2 domain-containing protein 0.0099 0.0211 0.3017
Brugia malayi Serotonin receptor 0.0009 0.0001 0.0017
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.009 0.009
Schistosoma mansoni histone deacetylase 1 2 3 0.013 0.0284 0.0284
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0128 0.0279 0.0279
Schistosoma mansoni DNA ligase IV 0.0019 0.0027 0.0027
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0033 0.0443
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0027 0.0027
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.025 0.0562 0.0562
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0033 0.0443
Trypanosoma brucei unspecified product 0.0049 0.0096 0.1349
Leishmania major protein kinase, putative 0.003 0.0052 0.0717
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0049 0.0769
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0002 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0039 0.0046
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0001 0.0001
Brugia malayi cell division control protein 2 homolog 0.0043 0.0081 0.1098
Loa Loa (eye worm) hypothetical protein 0.0071 0.0146 0.2084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Plasmodium vivax patched family protein, putative 0.0012 0.0009 0.0008
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0027 0.0358
Brugia malayi tRNA modification GTPase TrmE family protein 0.0099 0.0211 0.2849
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0128 0.0279 0.0279
Schistosoma mansoni tyrosine kinase 0.0029 0.0049 0.0049
Echinococcus granulosus Immunoglobulin 0.0015 0.0017 0.0017
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.008 0.0169 0.0169
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0049 0.0058
Onchocerca volvulus Protein patched homolog 0.0012 0.0009 0.014
Brugia malayi Fibronectin type III domain containing protein 0.0015 0.0017 0.0223
Entamoeba histolytica protein kinase, putative 0.0029 0.0049 0.0792
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0052 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0049 0.0094 0.1348
Schistosoma mansoni acetylcholinesterase 0.0011 0.0007 0.0007
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0029 0.0049 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Brugia malayi Carboxylesterase family protein 0.0011 0.0007 0.0098
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Leishmania major DNA polymerase eta, putative 0.0097 0.0207 0.2933
Echinococcus granulosus twitchin 0.0017 0.002 0.002
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0029 0.0049 0.0049
Onchocerca volvulus 0.0099 0.0211 0.3974
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0232 0.0568
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.003 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0121 0.0121
Schistosoma mansoni nck2/grb4 0.0099 0.0211 0.0211
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus granulosus intestinal type alkaline phosphatase 0.0161 0.0356 0.0356
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0232 0.3885
Echinococcus multilocularis integrin linked protein kinase 0.0029 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0004 0.0004
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0135 0.1935
Echinococcus granulosus 7tm_1 domain containing protein 0.0009 0.0001 0.0001
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.003 0.0399
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Echinococcus granulosus activin receptor type 0.003 0.0052 0.0052
Brugia malayi Myosin head containing protein 0.0012 0.0009 0.0117
Schistosoma mansoni ap endonuclease 0.0019 0.0025 0.0025
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0124 0.0124
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0119 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Leishmania major protein kinase, putative 0.0029 0.0049 0.0672
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis cyclin dependent kinase 1 0.0043 0.0081 0.0081
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0081 0.13
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0594 0.9703
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Brugia malayi nuclear hormone receptor 0.001 0.0003 0.0046
Brugia malayi hypothetical protein 0.0011 0.0006 0.0082
Brugia malayi Carboxylesterase family protein 0.0011 0.0007 0.0098
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0124 0.1776
Onchocerca volvulus 0.0099 0.0211 0.3974
Loa Loa (eye worm) hypothetical protein 0.0295 0.0668 0.9554
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0039 0.053
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0027 0.035
Echinococcus granulosus para nitrobenzyl esterase 0.0011 0.0007 0.0007
Echinococcus granulosus NCK adaptor protein 0.0099 0.0211 0.0211
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0027 0.0031
Brugia malayi Patched related family protein 4 0.0012 0.0009 0.0117
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0028 0.0028
Schistosoma mansoni ran 0.0021 0.003 0.003
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0025 0.0238
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0099 0.0211 0.0211
Brugia malayi Dopamine receptor protein 2 0.0009 0.0001 0.0017
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0049 0.0058
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0146 0.206
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.003 0.0056
Schistosoma mansoni nuclear hormone receptor 0.001 0.0003 0.0003
Trypanosoma brucei Flagellum attachment zone protein 20 0.0029 0.0049 0.0672
Trypanosoma brucei histone deacetylase 4 0.0308 0.0699 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0072 0.0148 0.0355
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis G-protein coupled receptor, putative 0.0009 0.0001 0.0001
Schistosoma mansoni protein kinase 0.003 0.0052 0.0052
Loa Loa (eye worm) RNA binding protein 0.0061 0.0124 0.1776
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0049 0.0792
Schistosoma mansoni nephrin 0.0015 0.0017 0.0017
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0029 0.0049 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0232 0.377
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0403
Echinococcus granulosus fibroblast growth factor receptor 4 0.0029 0.0049 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.0091 0.0194 0.2752
Echinococcus granulosus hypothetical protein 0.0099 0.0211 0.0211
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.07
Brugia malayi Importin beta-1 subunit 0.0028 0.0047 0.0639
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Onchocerca volvulus 0.0028 0.0047 0.0868
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0066 0.0917
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0012 0.0009 0.014
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Echinococcus granulosus tyrosine protein kinase Src64B 0.0128 0.0279 0.0279
Brugia malayi Furin-like cysteine rich region family protein 0.0029 0.0049 0.0661
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0099 0.0211 0.0211
Echinococcus granulosus g-protein coupled receptor 0.0009 0.0001 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni microtubule-associated protein tau 0.1363 0.3155 0.3155
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0052 0.0052
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0006 0.0006
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0049 0.07
Onchocerca volvulus 0.0021 0.003 0.0535
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0232 0.3316
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0049 0.0769
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0082 0.0172 0.0172
Giardia lamblia Kinase 0.0029 0.0049 0.0792
Echinococcus multilocularis histone deacetylase 3 0.0263 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Giardia lamblia Kinase, NEK 0.0029 0.0049 0.0792
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0028 0.0028
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0009 0.0001 0.0017
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0086
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0099 0.0211 0.2849
Echinococcus multilocularis neuropeptide FF receptor 2 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0104 0.1489
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0209 0.297
Echinococcus granulosus growth factor receptor bound protein 2 0.0099 0.0211 0.0211
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.009 0.009
Onchocerca volvulus 0.001 0.0003 0.004
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Onchocerca volvulus 0.0128 0.0279 0.5257
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0003 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0028 0.0028
Echinococcus multilocularis c src tyrosine kinase 0.0128 0.0279 0.0279
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Echinococcus multilocularis cyclin dependent kinase 5 0.0043 0.0081 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0001 0.0001
Echinococcus granulosus snurportin 1 0.0303 0.0687 0.0687
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0082 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Echinococcus granulosus tyrosine protein kinase Fyn 0.0128 0.0279 0.0279
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0029 0.0049 0.07
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0209 0.297
Schistosoma mansoni nuclear receptor 0.001 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0128 0.0279 0.0279
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0041 0.0657
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0049 0.0058
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0009 0.0001 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0634 0.1457 0.1457
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0066 0.1081
Echinococcus granulosus dual specificity testis-specific protein kinase 0.003 0.0052 0.0052
Echinococcus granulosus tyrosine protein kinase Srms 0.0128 0.0279 0.0279
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0052 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0001 0.0001
Loa Loa (eye worm) apoptosis regulator protein 0.0082 0.0172 0.2462
Echinococcus granulosus sterol regulatory element binding protein 0.0083 0.0176 0.0176
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0028 0.0028
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0071 0.1171
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0039 0.053
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0028 0.0381
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0364 0.083 0.1
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0028 0.051
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0088 0.0088
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0017 0.0019
Brugia malayi protein C24B5.3 0.0012 0.0009 0.0117
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0211 0.2849
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0021 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0083 0.0176 0.251
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0001 0.0001
Echinococcus multilocularis histone deacetylase 6 0.0308 0.0699 0.0699
Schistosoma mansoni suppressor of cytokine signaling 0.0099 0.0211 0.0211
Echinococcus multilocularis roundabout 2 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0099 0.0211 0.3017
Loa Loa (eye worm) TK/ABL protein kinase 0.0128 0.0279 0.3985
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0025 0.0323
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0066 0.0917
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Entamoeba histolytica cysteine surface protein, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.003 0.0056
Schistosoma mansoni tyrosine kinase 0.0128 0.0279 0.0279
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0082 0.0172 0.0172
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.0308 0.0699 1
Brugia malayi Muscleblind-like protein 0.0295 0.0668 0.9023
Schistosoma mansoni neuropeptide receptor 0.0009 0.0001 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.009 0.009
Trypanosoma brucei cdc2-related kinase 1 0.0043 0.0081 0.1136
Trypanosoma cruzi cdc2-related kinase 1 0.0043 0.0081 0.1136
Brugia malayi Dopamine receptor protein 1 0.0009 0.0001 0.0017
Brugia malayi hypothetical protein 0.0009 0.0001 0.0017
Leishmania major GTP-binding protein, putative 0.0021 0.003 0.0399
Trypanosoma cruzi cdc2-related kinase 1 0.0043 0.0081 0.1136
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.003 0.0028
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0121 0.0121
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.003 0.0393
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0049 0.0792
Mycobacterium ulcerans hypothetical protein 0.0022 0.0033 0.0032
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0052 0.0717
Trypanosoma brucei histone deacetylase, putative 0.0308 0.0699 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0009 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.102
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0025 0.0352
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1711 0.3964 1
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0066 0.1081
Brugia malayi glutaminase DH11.1 0.0271 0.0612 0.826
Echinococcus granulosus SH2 motif 0.0099 0.0211 0.0211
Brugia malayi integrin-linked kinase 0.0029 0.0049 0.0661
Giardia lamblia Kinase, CMGC CDK 0.0043 0.0081 0.134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0028 0.0403
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0033 0.0443
Echinococcus multilocularis histone deacetylase 7 0.0308 0.0699 0.0699
Echinococcus granulosus histone deacetylase 7 0.0308 0.0699 0.0699
Echinococcus granulosus neuropeptide receptor A26 0.0009 0.0001 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0403 0.0919 0.0919
Trichomonas vaginalis rotamase, putative 0.0033 0.0058 0.0909
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0146 0.206
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0232 0.3296
Schistosoma mansoni cpg binding protein 0.003 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0018
Plasmodium falciparum histone deacetylase 1 0.0263 0.0594 0.0734
Onchocerca volvulus 0.0011 0.0007 0.0113
Loa Loa (eye worm) hypothetical protein 0.0053 0.0104 0.1489
Plasmodium vivax tyrosine kinase-like protein, putative 0.0029 0.0049 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0146 0.0172
Brugia malayi hypothetical protein 0.0015 0.0017 0.0223
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0082 0.0172 0.0172
Schistosoma mansoni growth hormone secretagogue receptor 0.0009 0.0001 0.0001
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1711 0.3964 1
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0594 0.9703
Brugia malayi RNA, U transporter 1 0.0081 0.0169 0.2285
Brugia malayi nuclear receptor NHR-67 0.001 0.0003 0.0046
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0049 0.07
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.102
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0596 0.137 0.1698
Leishmania major DNA polymerase eta, putative 0.0047 0.0092 0.1285
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0049 0.0769
Schistosoma mansoni tyrosine kinase 0.0128 0.0279 0.0279
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0029 0.0049 0.0792
Trichomonas vaginalis spcc417.12 protein, putative 0.0011 0.0007 0.0085
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0001 0.0001
Brugia malayi Tyrosine-protein kinase abl-1 0.0128 0.0279 0.3763
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0029 0.0049 0.07
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0049 0.0792
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0017 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0401
Brugia malayi Protein kinase domain containing protein 0.0128 0.0279 0.3763
Entamoeba histolytica receptor protein kinase, putative 0.0029 0.0049 0.0792
Onchocerca volvulus 0.0128 0.0279 0.5257
Brugia malayi SH2 domain containing protein 0.0128 0.0279 0.3763
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0009 0.0001 0.0001
Echinococcus granulosus dna polymerase kappa 0.0098 0.0209 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0094 0.1322
Echinococcus granulosus roundabout 2 0.0015 0.0017 0.0017
Brugia malayi histone deacetylase 3 (HD3) 0.0263 0.0594 0.8016
Entamoeba histolytica deoxycytidyl transferase, putative 0.0072 0.0148 0.2465
Schistosoma mansoni topbp1 0.0019 0.0027 0.0027
Plasmodium vivax histone deacetylase 2, putative 0.0308 0.0699 0.0866
Echinococcus granulosus nibrin 0.0019 0.0027 0.0027
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.003 0.0056
Schistosoma mansoni DNA polymerase IV / kappa 0.0022 0.0033 0.0033
Echinococcus multilocularis tyrosine kinase 0.0029 0.0049 0.0049
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0028 0.0028
Schistosoma mansoni adapter molecule crk 0.0099 0.0211 0.0211
Schistosoma mansoni hypothetical protein 0.0029 0.0049 0.0049
Schistosoma mansoni nuclear hormone receptor 0.002 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0082 0.0172 0.0172
Echinococcus granulosus tachykinin peptides receptor 99D 0.0009 0.0001 0.0001
Schistosoma mansoni protein kinase 0.003 0.0052 0.0052
Echinococcus multilocularis Niemann Pick C1 protein 0.0278 0.0628 0.0628
Trypanosoma brucei unspecified product 0.0049 0.0096 0.1349
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0104
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0104 0.0127
Echinococcus multilocularis sex peptide receptor 0.0009 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0146 0.0172
Brugia malayi Flap endonuclease-1 0.0026 0.0041 0.0553
Echinococcus granulosus N chimaerin 0.0099 0.0211 0.0211
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.003 0.0393
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Loa Loa (eye worm) TK/DDR protein kinase 0.0029 0.0049 0.07
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.102
Brugia malayi SH2 domain containing protein 0.0099 0.0211 0.2849
Onchocerca volvulus 0.0012 0.0009 0.014
Onchocerca volvulus 0.0011 0.0007 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.035
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0001 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.1363 0.3155 0.3155
Echinococcus multilocularis dro:myosuppressin receptor 0.0009 0.0001 0.0001
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0092 0.1285
Echinococcus multilocularis SH2 domain containing protein 7 0.0099 0.0211 0.0211
Brugia malayi Niemann-Pick C1 protein precursor 0.0194 0.0434 0.5861
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0052 0.0052
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0135 0.0135
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0005 0.0035
Brugia malayi cytokine inducible SH2-containing protein 5 0.0099 0.0211 0.2849
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0029 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0086
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0017 0.0019
Mycobacterium ulcerans chorismate synthase 0.3469 0.8059 1
Schistosoma mansoni hypothetical protein 0.0082 0.0172 0.0172
Schistosoma mansoni protein kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0128 0.0279 0.0279
Onchocerca volvulus 0.0029 0.0049 0.0903
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0049 0.0792
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0059 0.0802
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0028 0.0381
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0236
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0099 0.0211 0.0211
Echinococcus granulosus phd:f box containing protein 0.0016 0.0017 0.0017
Brugia malayi Protein kinase domain containing protein 0.0029 0.0049 0.0661
Trypanosoma cruzi histone deacetylase, putative 0.0308 0.0699 1
Brugia malayi Patched family protein 0.0012 0.0009 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0028 0.0381
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0146 0.2428
Echinococcus granulosus tyrosine kinase 0.0029 0.0049 0.0049
Plasmodium falciparum protein kinase, putative 0.003 0.0052 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0001 0.0001
Schistosoma mansoni tensin-related 0.0099 0.0211 0.0211
Echinococcus multilocularis insulin receptor 0.0029 0.0049 0.0049
Echinococcus multilocularis sterol regulatory element binding protein 0.0083 0.0176 0.0176
Toxoplasma gondii chorismate synthase, putative 0.3469 0.8059 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0048
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.003 0.0008
Schistosoma mansoni GTPase activating protein 0.0099 0.0211 0.0211
Entamoeba histolytica hypothetical protein 0.0029 0.0049 0.0792
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0232 0.0232
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0028 0.0028
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0124
Schistosoma mansoni protein tyrosine kinase 0.0029 0.0049 0.0049
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0049 0.0049
Trypanosoma cruzi histone deacetylase 1, putative 0.0263 0.0594 0.8483
Echinococcus multilocularis protein kinase 0.0029 0.0049 0.0049

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 64 nM Inhibition of [125I]- IOXY binding to human Opioid receptor kappa1 ChEMBL. 16033256
Ki (binding) = 64 nM Inhibition of [125I]- IOXY binding to human Opioid receptor kappa1 ChEMBL. 16033256
Ki (binding) = 6470 nM Inhibition of [125I]- IOXY binding to human Opioid receptor delta1 ChEMBL. 16033256
Ki (binding) = 6470 nM Inhibition of [125I]- IOXY binding to human Opioid receptor delta1 ChEMBL. 16033256
Ki (binding) > 10000 nM Inhibition of [125I]- IOXY binding to human Opioid receptor mu1 ChEMBL. 16033256
Ki (binding) > 10000 nM Inhibition of [125I]- IOXY binding to human Opioid receptor mu1 ChEMBL. 16033256
Selectivity (binding) = 95 Relative affinity for human opioid receptor delta1 and kappa1 ChEMBL. 16033256
Selectivity (binding) > 150 Relative affinity for human opioid receptor mu1 and kappa1 ChEMBL. 16033256

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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