Detailed information for compound 339738

Basic information

Technical information
  • TDR Targets ID: 339738
  • Name: 4-[1-(2-methylpropyl)piperidin-4-yl]oxybenzon itrile
  • MW: 258.359 | Formula: C16H22N2O
  • H donors: 0 H acceptors: 1 LogP: 3.53 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CN1CCC(CC1)Oc1ccc(cc1)C#N)C
  • InChi: 1S/C16H22N2O/c1-13(2)12-18-9-7-16(8-10-18)19-15-5-3-14(11-17)4-6-15/h3-6,13,16H,7-10,12H2,1-2H3
  • InChiKey: VIRFAIUTUMIHHI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[(1-isobutyl-4-piperidyl)oxy]benzonitrile
  • 4-[(1-isobutyl-4-piperidinyl)oxy]benzonitrile
  • 4-[1-(2-methylpropyl)piperidin-4-yl]oxybenzenecarbonitrile

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histamine receptor H3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Echinococcus multilocularis somatostatin receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Echinococcus multilocularis G-protein coupled receptor, putative 0.0932 0.7396 0.7396
Brugia malayi Peroxidasin 0.0088 0.0533 0.0533
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0167 0.0167
Leishmania major hypothetical protein, conserved 0.005 0.0225 0.0674
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Echinococcus granulosus intermediate filament protein 0.006 0.0307 0.0307
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.088 0.088
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0002 0.0002
Onchocerca volvulus 0.0932 0.7396 0.8973
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0028 0.0129
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0057 0.0287 0.0287
Mycobacterium ulcerans oxidoreductase 0.0276 0.2061 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Loa Loa (eye worm) animal heme peroxidase 0.0088 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0114 0.0746 0.2234
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0763 0.3449
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0098 0.0292
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Leishmania major mitochondrial DNA polymerase beta 0.0334 0.2534 0.7589
Echinococcus multilocularis geminin 0.036 0.2746 0.2746
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0116 0.0763 0.3614
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.0763 0.0763
Trichomonas vaginalis aldo-keto reductase, putative 0.0114 0.0746 0.0907
Echinococcus multilocularis tar DNA binding protein 0.0061 0.032 0.032
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0287 0.086
Loa Loa (eye worm) hypothetical protein 0.0057 0.0287 0.0287
Leishmania major DNA polymerase eta, putative 0.0022 0.0002 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0291 0.2183 0.2183
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0129 0.0387
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0108 0.0699 0.0699
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0287 0.0349
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0018 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0098 0.0098
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0088 0.0535 0.1603
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0811 0.3928
Echinococcus granulosus g protein coupled receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Brugia malayi G protein-coupled receptor F59B2.13 0.0932 0.7396 0.7396
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Brugia malayi 6-phosphofructokinase 0.0116 0.0763 0.0763
Trichomonas vaginalis aldo/keto reductase, putative 0.0276 0.2061 0.2505
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0299 0.2251 0.2251
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0002 0.0005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Brugia malayi Animal haem peroxidase family protein 0.0088 0.0533 0.0533
Brugia malayi hypothetical protein 0.013 0.0876 0.0876
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0465 0.0565
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.088 0.088
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0127
Echinococcus multilocularis neuropeptide s receptor 0.0932 0.7396 0.7396
Leishmania major hypothetical protein, conserved 0.0038 0.0127 0.0381
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0028 0.0084
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0064 0.0193
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0028 0.0129
Echinococcus granulosus neuropeptide receptor 0.0932 0.7396 0.7396
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0114 0.0746 0.2234
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0762 0.0762
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) oxidoreductase 0.0276 0.2061 0.2061
Brugia malayi jmjC domain containing protein 0.0062 0.0327 0.0327
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0762 0.0762
Plasmodium vivax importin-beta 2, putative 0.003 0.0064 0.0193
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis 0.0026 0.0028 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0028 0.0129
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0026 0.0028 0.0129
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0811 0.0811
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.0697 0.0697
Echinococcus granulosus G protein coupled receptor 139 0.0932 0.7396 0.7396
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0763 0.0927
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0287 0.086
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0127 0.0127
Plasmodium vivax phosphodiesterase gamma, putative 0.0057 0.0287 0.086
Schistosoma mansoni tar DNA-binding protein 0.0061 0.032 0.032
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0225 0.0674
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0127 0.0381
Trypanosoma cruzi aldo/keto reductase, putative 0.0114 0.0746 0.2234
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Plasmodium falciparum aldehyde reductase, putative 0.0114 0.0746 1
Brugia malayi follicle stimulating hormone receptor 0.1197 0.9553 0.9553
Onchocerca volvulus 0.0932 0.7396 0.8973
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0127 0.0155
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0125 0.0841 0.0841
Echinococcus granulosus 7TM GPCR rhodopsin 0.0932 0.7396 0.7396
Onchocerca volvulus 0.0932 0.7396 0.8973
Loa Loa (eye worm) blistered cuticle protein 3 0.0088 0.0533 0.0533
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0026 0.0028 0.0129
Loa Loa (eye worm) G-protein coupled receptor 0.0932 0.7396 0.7396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Leishmania major hypothetical protein, conserved 0.0057 0.0287 0.086
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0028 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0028 0.0129
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0307 0.0307
Echinococcus granulosus neuropeptide FF receptor 2 0.0932 0.7396 0.7396
Brugia malayi Importin beta-1 subunit 0.003 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Leishmania major aldo-keto reductase-like protein 0.0276 0.2061 0.6172
Entamoeba histolytica alcohol dehydrogenase, putative 0.0114 0.0746 0.3372
Schistosoma mansoni hypothetical protein 0.0026 0.0028 0.0028
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0932 0.7396 0.7396
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0028 0.0129
Loa Loa (eye worm) TYRA-2 protein 0.0932 0.7396 0.7396
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0287 0.0287
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0028 0.0129
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0327 0.0327
Echinococcus granulosus histone lysine methyltransferase setb 0.013 0.088 0.088
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0098 0.0098
Echinococcus granulosus tm gpcr rhodopsin 0.0932 0.7396 0.7396
Onchocerca volvulus 0.0932 0.7396 0.8973
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Loa Loa (eye worm) oxidoreductase 0.0276 0.2061 0.2061
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0932 0.7396 0.7396
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0167 0.0167
Brugia malayi RE15519p 0.0932 0.7396 0.7396
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0129 0.0157
Schistosoma mansoni neuropeptide receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0276 0.2061 0.2505
Schistosoma mansoni biogenic amine receptor 0.0932 0.7396 0.7396
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0057 0.0287 0.1298
Entamoeba histolytica aldose reductase, putative 0.0276 0.2061 0.9317
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0433 0.334 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Brugia malayi Dopamine receptor protein 1 0.0932 0.7396 0.7396
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Echinococcus granulosus dro:myosuppressin receptor 0.0932 0.7396 0.7396
Schistosoma mansoni tar DNA-binding protein 0.0061 0.032 0.032
Brugia malayi Steroid receptor seven-up type 2 0.0108 0.0699 0.0699
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0299 0.2251 0.2251
Echinococcus multilocularis sex peptide receptor 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.032 0.2423 0.2423
Loa Loa (eye worm) hypothetical protein 0.0057 0.0287 0.0287
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0002 0.0005
Brugia malayi Inositol-1 0.0038 0.0129 0.0129
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.0697 0.0697
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0117 0.0775 0.2322
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Schistosoma mansoni opsin-like receptor 0.0932 0.7396 0.7396
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0129 0.0387
Onchocerca volvulus 0.1034 0.8228 1
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus importin subunit beta 1 0.003 0.0064 0.0064
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.032 0.032
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Brugia malayi NADH-dependent xylose reductase 0.0114 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Onchocerca volvulus 0.0088 0.0533 0.0501
Trypanosoma cruzi aldo-keto reductase 0.0276 0.2061 0.6172
Trichomonas vaginalis set domain proteins, putative 0.1034 0.8227 1
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0225 0.0674
Echinococcus multilocularis g protein coupled receptor 0.0932 0.7396 0.7396
Leishmania major cytochrome p450-like protein 0.0026 0.0028 0.0084
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0057 0.0287 0.086
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0026 0.0028 0.0129
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0057 0.0287 0.086
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0087 0.0087
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0087 0.0087
Schistosoma mansoni polycystin 1-related 0.0043 0.0167 0.0167
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0127 0.0127
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis aldo keto reductase 0.0276 0.2061 0.2061
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis aldo keto reductase 0.0276 0.2061 0.2061
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0287 0.086
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0057 0.0287 0.0287
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0075 0.0091
Schistosoma mansoni aryl hydrocarbon receptor 0.0056 0.0277 0.0277
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0127 0.0155
Schistosoma mansoni hypothetical protein 0.036 0.2746 0.2746
Onchocerca volvulus 0.0932 0.7396 0.8973
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni amine GPCR 0.0932 0.7396 0.7396
Leishmania major cytochrome p450-like protein 0.0034 0.0098 0.0292
Mycobacterium tuberculosis Conserved protein 0.0038 0.0127 0.0611
Entamoeba histolytica hypothetical protein 0.011 0.0715 0.3233
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0028 0.0129
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.0697 0.2088
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni single-minded 0.0056 0.0277 0.0277
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0225 0.0674
Brugia malayi Cytochrome P450 family protein 0.0034 0.0098 0.0098
Trypanosoma brucei aldo/keto reductase, putative 0.0114 0.0746 0.2234
Schistosoma mansoni intermediate filament proteins 0.006 0.0307 0.0307
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0075 0.0225
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Brugia malayi neuropeptide F receptor 0.0932 0.7396 0.7396
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Brugia malayi putative neuropeptide receptor NPR1 0.0932 0.7396 0.7396
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0932 0.7396 0.7396
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0028 0.0129
Echinococcus granulosus allatostatin A receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0287 0.0349
Echinococcus granulosus fmrfamide receptor 0.0932 0.7396 0.7396
Echinococcus granulosus geminin 0.036 0.2746 0.2746
Plasmodium falciparum phosphodiesterase delta, putative 0.0057 0.0287 0.3849
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Entamoeba histolytica aldose reductase, putative 0.0276 0.2061 0.9317
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0127
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0002 0.0002
Brugia malayi hypothetical protein 0.0043 0.0167 0.0167
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0127 0.0127
Echinococcus multilocularis aldo keto reductase 0.0276 0.2061 0.2061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0202 0.0605
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0081 0.0081
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0642 0.0642
Schistosoma mansoni hypothetical protein 0.0069 0.0382 0.0382
Entamoeba histolytica hypothetical protein 0.011 0.0715 0.3233
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0129 0.0157
Echinococcus multilocularis 6 phosphofructokinase 0.0116 0.0763 0.0763
Entamoeba histolytica aldose reductase, putative 0.0276 0.2061 0.9317
Loa Loa (eye worm) oxidoreductase 0.0276 0.2061 0.2061
Echinococcus multilocularis snurportin 1 0.032 0.2423 0.2423
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0002 0.0002
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.0697 0.2088
Echinococcus granulosus g protein coupled receptor 0.0932 0.7396 0.7396
Brugia malayi Serotonin receptor 0.0932 0.7396 0.7396
Brugia malayi G-protein coupled receptor 0.0932 0.7396 0.7396
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0287 0.086
Onchocerca volvulus Neuropeptide F receptor homolog 0.0932 0.7396 0.8973
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis G protein coupled receptor 139 0.0932 0.7396 0.7396
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Echinococcus multilocularis aldehyde reductase 0.0162 0.1136 0.1136
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.2212 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0327 0.0327
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0079 0.0465 0.0565
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0079 0.0465 0.0465
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0202 0.0605
Schistosoma mansoni opsin-like receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0276 0.2061 0.2061
Schistosoma mansoni neuropeptide receptor 0.0932 0.7396 0.7396
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.1105 0.3309
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0433 0.334 1
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0089 0.0545 0.0515
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0202 0.0605
Echinococcus multilocularis g protein coupled receptor 0.0932 0.7396 0.7396
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0079 0.0465 0.0465
Echinococcus multilocularis microtubule associated protein 2 0.0755 0.596 0.596
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0081 0.0081
Onchocerca volvulus 0.0932 0.7396 0.8973
Echinococcus multilocularis lamin dm0 0.006 0.0307 0.0307
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0127 0.0127
Brugia malayi Serotonin receptor 0.0932 0.7396 0.7396
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0117 0.0775 0.2322
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.0032 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0032 0.0081 0.0081
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0129 0.0387
Brugia malayi Cytochrome P450 family protein 0.0026 0.0028 0.0028
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0433 0.334 1
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0075 0.0225
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.086
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0028 0.0129
Onchocerca volvulus Peroxidasin homolog 0.0088 0.0533 0.0501
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0129 0.0387
Onchocerca volvulus 0.0051 0.0239 0.0137
Brugia malayi G protein-coupled receptor 0.0932 0.7396 0.7396
Schistosoma mansoni survival motor neuron protein 0.0051 0.0239 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0028 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0309 0.0375
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0088 0.0535 0.1603
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Schistosoma mansoni hypothetical protein 0.011 0.0715 0.0715
Onchocerca volvulus 0.0932 0.7396 0.8973
Giardia lamblia Aldose reductase 0.0276 0.2061 0.9317
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0276 0.2061 0.6172
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0127 0.0611
Echinococcus granulosus GPCR family 2 0.0032 0.0081 0.0081
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0932 0.7396 0.7396
Echinococcus granulosus histone acetyltransferase KAT2B 0.0088 0.0535 0.0535
Echinococcus multilocularis fmrfamide receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0932 0.7396 0.7396
Brugia malayi Animal haem peroxidase family protein 0.0088 0.0533 0.0533
Onchocerca volvulus 0.0042 0.0158 0.0038
Onchocerca volvulus 0.0932 0.7396 0.8973
Mycobacterium ulcerans beta-lactamase 0.0038 0.0127 0.0611
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0028 0.0028
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus adenylate cyclase 9 0.0089 0.0545 0.0545
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0075 0.0091
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0127 0.0127
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0811 0.3928
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0057 0.0287 0.0287
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0433 0.334 0.334
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0087 0.0261
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0286 0.0855
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0287 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Echinococcus granulosus lamin 0.006 0.0307 0.0307
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.013 0.088 0.088
Loa Loa (eye worm) phosphofructokinase 0.0116 0.0763 0.0763
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0237 0.1745 0.1745
Onchocerca volvulus 0.013 0.088 0.0929
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0026 0.0028 0.0129
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.3849
Echinococcus granulosus aldo keto reductase 0.0276 0.2061 0.2061
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus adenylate cyclase type IX 0.0125 0.0838 0.0838
Toxoplasma gondii hypothetical protein 0.0054 0.0258 0.0773
Brugia malayi intermediate filament protein 0.006 0.0307 0.0307
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0087 0.0261
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0127
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0127 0.0611
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0002 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Onchocerca volvulus 0.006 0.0307 0.0222
Mycobacterium ulcerans hypothetical protein 0.0038 0.0127 0.0611
Trypanosoma brucei unspecified product 0.0022 0.0002 0.0005
Echinococcus granulosus g-protein coupled receptor 0.0932 0.7396 0.7396
Onchocerca volvulus 0.0276 0.2061 0.2387
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Onchocerca volvulus 0.0276 0.2061 0.2387
Onchocerca volvulus 0.0276 0.2061 0.2387
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0087 0.0087
Echinococcus granulosus dna polymerase eta 0.0022 0.0002 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0087 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0932 0.7396 0.7396
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0087 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0642 0.0642
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.0697 0.0697
Echinococcus granulosus peptide allatostatin:somatostatin 0.0932 0.7396 0.7396
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0237 0.1745 0.1745
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0127 0.0611
Brugia malayi larval opioid receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.086
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0087 0.0261
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0117 0.0775 0.0775
Onchocerca volvulus 0.0932 0.7396 0.8973
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0811 0.3928
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0237 0.1745 0.1745
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0081 0.0081
Echinococcus granulosus aldehyde reductase 0.0162 0.1136 0.1136
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0697 0.0848
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.2212 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0763 0.3449
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0127 0.0381
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0697 0.2088
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0028 0.0129
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0002 0.0002
Schistosoma mansoni growth hormone secretagogue receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis musashi 0.006 0.0307 0.0307
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0237 0.1745 0.1745
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0117 0.0775 0.0943
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0167 0.0167
Brugia malayi acetyltransferase, GNAT family protein 0.0299 0.2251 0.2251
Echinococcus granulosus somatostatin receptor 0.0932 0.7396 0.7396
Brugia malayi GnHR receptor homolog 0.0932 0.7396 0.7396
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0327 0.0327
Loa Loa (eye worm) TAR-binding protein 0.0061 0.032 0.032
Onchocerca volvulus Peroxidase homolog 0.0088 0.0533 0.0501
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0433 0.334 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.1781 0.864
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis aldo keto reductase 0.0276 0.2061 0.2061
Loa Loa (eye worm) hypothetical protein 0.0188 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0075 0.0091
Brugia malayi Adenylyl cyclase protein 0.0089 0.0545 0.0545
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0129 0.5
Echinococcus granulosus tar DNA binding protein 0.0061 0.032 0.032
Onchocerca volvulus 0.0276 0.2061 0.2387
Leishmania major DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0079 0.0465 0.0465
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0018 0.0022
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0079 0.0465 0.0465
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.0349
Schistosoma mansoni peroxidasin 0.0088 0.0533 0.0533
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0327 0.0327
Brugia malayi neuropeptide F receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.013 0.088 0.088
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis neuropeptide receptor A26 0.0932 0.7396 0.7396
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0087 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0287 0.086
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0018 0.0022
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Schistosoma mansoni lipoxygenase 0.0189 0.1357 0.1357
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0002 0.0005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0127 0.0127
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0127 0.0611
Mycobacterium ulcerans hypothetical protein 0.0114 0.0746 0.3615
Loa Loa (eye worm) hypothetical protein 0.005 0.0225 0.0225
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.2212 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0032 0.0081 0.0081
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0026 0.0028 0.0129
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0167 0.05
Entamoeba histolytica acetyltransferase, GNAT family 0.0081 0.0476 0.2151
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0746 0.0907
Echinococcus granulosus microtubule associated protein 2 0.0755 0.596 0.596
Onchocerca volvulus 0.0088 0.0533 0.0501
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0057 0.0287 0.0287
Brugia malayi bHLH-PAS transcription factor 0.0042 0.0158 0.0158
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0129 0.0584
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0334 0.2534 0.7589
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0129 0.0157
Brugia malayi Animal haem peroxidase family protein 0.0088 0.0533 0.0533
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.0763 0.0763
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0026 0.0028 0.0129
Trichomonas vaginalis aldo/keto reductase, putative 0.0276 0.2061 0.2505
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0287 0.3849
Giardia lamblia Histone acetyltransferase GCN5 0.0081 0.0476 0.2151
Brugia malayi Blistered cuticle protein 3 0.0088 0.0533 0.0533
Echinococcus multilocularis allatostatin A receptor 0.0932 0.7396 0.7396
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0026 0.0028 0.0129
Echinococcus granulosus neuropeptide s receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0763 0.0927
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0127 0.0155
Echinococcus multilocularis neuropeptides capa receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis adenylate cyclase 9 0.0089 0.0545 0.0545
Trypanosoma brucei protein kinase, putative 0.0108 0.0697 0.2088
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0098 0.0098
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0087 0.0261
Echinococcus multilocularis survival motor neuron protein 1 0.0252 0.1871 0.1871
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trichomonas vaginalis aldo-keto reductase, putative 0.0114 0.0746 0.0907
Echinococcus granulosus tm gpcr rhodopsin 0.0932 0.7396 0.7396
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0117 0.0775 0.0775
Echinococcus multilocularis serotonin receptor 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus lamin dm0 0.006 0.0307 0.0307
Loa Loa (eye worm) beta-lactamase 0.0038 0.0127 0.0127
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0225 0.302
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0763 0.0927
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.0763 0.2284
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0433 0.334 0.334
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Schistosoma mansoni DNA polymerase eta 0.0022 0.0002 0.0002
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0433 0.334 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0081 0.0081
Brugia malayi Dopamine receptor 0.0932 0.7396 0.7396
Toxoplasma gondii ABC1 family protein 0.0038 0.0127 0.0381
Schistosoma mansoni adenoreceptor 0.0932 0.7396 0.7396
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0116 0.0763 0.3218
Entamoeba histolytica hypothetical protein 0.011 0.0715 0.3233
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.0697 0.2088
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0028 0.0129
Schistosoma mansoni histamine h1 receptor 0.0932 0.7396 0.7396
Brugia malayi TAR-binding protein 0.0061 0.032 0.032
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.032 0.032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.088 0.088
Mycobacterium leprae Possible oxidoreductase 0.0114 0.0746 0.3531
Echinococcus granulosus g protein coupled receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis importin subunit beta 1 0.003 0.0064 0.0064
Schistosoma mansoni lamin 0.006 0.0307 0.0307
Schistosoma mansoni cytochrome P450 0.0026 0.0028 0.0028
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.086
Schistosoma mansoni inositol monophosphatase 0.0038 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Echinococcus granulosus neuropeptide Y receptor 0.0932 0.7396 0.7396
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0002 0.0002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0932 0.7396 0.7396
Schistosoma mansoni tar DNA-binding protein 0.0061 0.032 0.032
Echinococcus granulosus serotonin receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.2534 0.7589
Echinococcus granulosus peroxidasin 0.0088 0.0533 0.0533
Echinococcus granulosus voltage gated potassium channel subunit 0.0114 0.0746 0.0746
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.125 0.6062
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0327 0.0327
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0075 0.034
Loa Loa (eye worm) animal heme peroxidase 0.0088 0.0533 0.0533
Schistosoma mansoni tar DNA-binding protein 0.0061 0.032 0.032
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0127 0.0489
Loa Loa (eye worm) cytochrome P450 0.0026 0.0028 0.0028
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0327 0.0327
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.0932 0.7396 0.7396
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0026 0.0028 0.0129
Brugia malayi hypoxia-induced factor 1 0.0174 0.1232 0.1232
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis dna polymerase eta 0.0022 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0026 0.0028 0.0129
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0075 0.034
Loa Loa (eye worm) neuropeptide F receptor 0.0932 0.7396 0.7396
Plasmodium falciparum phosphodiesterase gamma, putative 0.0057 0.0287 0.3849
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0697 0.0697
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0087 0.0087
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.0697 0.3153
Schistosoma mansoni neuropeptide F-like receptor 0.0932 0.7396 0.7396
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0057 0.0287 0.0287
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0127 0.0381
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0127 0.0611
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0237 0.1745 0.1745
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0167
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0059 0.0298 0.0298
Brugia malayi sulfakinin receptor protein 0.0932 0.7396 0.7396
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0057 0.0287 0.0287
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0932 0.7396 0.7396
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0127 0.0611
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0932 0.7396 0.7396
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0459 0.0459
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0114 0.0746 0.0746
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.013 0.088 0.088
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0087 0.0261
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Giardia lamblia Aldose reductase 0.0276 0.2061 0.9317
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0338 0.2571 0.2571
Brugia malayi putative neuropeptide receptor 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.0032 0.0081 0.0081
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0327 0.0327
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0642 0.0642
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0932 0.7396 0.7396
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0932 0.7396 0.7396
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0932 0.7396 0.7396
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Loa Loa (eye worm) animal heme peroxidase 0.0088 0.0533 0.0533
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Leishmania major hypothetical protein, conserved 0.0057 0.0287 0.086
Brugia malayi phosphofructokinase 0.0116 0.0763 0.0763
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0127 0.0381
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.034 0.034
Loa Loa (eye worm) hypoxia-induced factor 1 0.0174 0.1232 0.1232
Leishmania major importin beta-1 subunit, putative 0.0024 0.0018 0.0055
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0108 0.0699 0.0699
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1197 0.9553 0.9553
Schistosoma mansoni hypothetical protein 0.0043 0.0167 0.0167
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.1252 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0811 0.0811
Onchocerca volvulus 0.006 0.0307 0.0222
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0087 0.0416
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Schistosoma mansoni loxhd1 0.0043 0.0167 0.0167
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0189 0.1357 0.1357
Trypanosoma cruzi aldo/keto reductase, putative 0.0276 0.2061 0.6172
Echinococcus multilocularis RUN 0.0043 0.0167 0.0167
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0127 0.0611
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0932 0.7396 0.7396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0002 0.0007
Schistosoma mansoni alpha-1 adrenergic receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0114 0.0746 0.2234
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0127
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0127
Onchocerca volvulus 0.0085 0.0514 0.0477
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0932 0.7396 0.7396
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0028 0.0084
Schistosoma mansoni hypothetical protein 0.0051 0.0239 0.0239
Onchocerca volvulus 0.0114 0.0746 0.0764
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0028 0.0129
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0075 0.5
Schistosoma mansoni lamin 0.006 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.013 0.088 0.088
Schistosoma mansoni amine GPCR 0.0932 0.7396 0.7396
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0096 0.0598 0.1791
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0079 0.0465 0.0465
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Echinococcus multilocularis neuropeptides capa receptor 0.0932 0.7396 0.7396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0237 0.1745 0.1745
Echinococcus granulosus single minded 2 0.0042 0.0158 0.0158
Loa Loa (eye worm) nuclear hormone receptor 0.0097 0.061 0.061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0276 0.2061 0.2061
Echinococcus granulosus tm gpcr rhodopsin 0.0932 0.7396 0.7396
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0057 0.0287 0.0287
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.086
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0307 0.0307
Echinococcus multilocularis g-protein coupled receptor 0.0932 0.7396 0.7396
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Onchocerca volvulus Peroxidasin homolog 0.0088 0.0533 0.0501
Brugia malayi isocitrate dehydrogenase 0.0033 0.0087 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0028 0.0129
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0087 0.1168
Entamoeba histolytica hypothetical protein 0.011 0.0715 0.3233
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.2212 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni opsin-like receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0287 0.0349
Echinococcus granulosus orexin receptor type 2 0.0932 0.7396 0.7396
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0276 0.2061 0.2061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0002 0.0002
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Echinococcus multilocularis transfer RNA-Lys 0.0042 0.0158 0.0158
Brugia malayi G-protein coupled receptor 0.0932 0.7396 0.7396
Echinococcus granulosus hypothetical protein 0.0932 0.7396 0.7396
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0028 0.0129
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0028 0.0084
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Echinococcus multilocularis neuropeptide receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Brugia malayi MH2 domain containing protein 0.0116 0.0762 0.0762
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0932 0.7396 0.7396
Schistosoma mansoni inositol monophosphatase 0.0038 0.0129 0.0129
Plasmodium falciparum histone acetyltransferase GCN5 0.0081 0.0476 0.6377
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0075 0.0091
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni neuropeptide f receptor 76f 0.0932 0.7396 0.7396
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.3849
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0287 0.0349
Onchocerca volvulus 0.0932 0.7396 0.8973
Echinococcus multilocularis neuropeptide Y receptor 0.0932 0.7396 0.7396
Brugia malayi AKH receptor 0.0932 0.7396 0.7396
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0932 0.7396 0.7396
Echinococcus granulosus tachykinin peptides receptor 99D 0.0932 0.7396 0.7396
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0098 0.0466
Mycobacterium leprae Probable lipase LipE 0.0038 0.0127 0.0489
Echinococcus multilocularis neuropeptide Y receptor 0.0932 0.7396 0.7396
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0129 0.062
Trichomonas vaginalis aldo/keto reductase, putative 0.0276 0.2061 0.2505
Echinococcus multilocularis peroxidasin 0.0088 0.0533 0.0533
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0932 0.7396 0.7396
Brugia malayi PAS domain containing protein 0.0056 0.0277 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0763 0.0927
Schistosoma mansoni importin beta-1 0.003 0.0064 0.0064
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0287 0.3849
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0908 0.7207 0.7207
Echinococcus multilocularis voltage gated potassium channel subunit 0.0114 0.0746 0.0746
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0433 0.334 1
Echinococcus multilocularis orexin receptor type 2 0.0932 0.7396 0.7396
Leishmania major ATP-dependent phosphofructokinase 0.0116 0.0763 0.2284
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0117 0.0775 0.2322
Leishmania major cytochrome p450-like protein 0.0026 0.0028 0.0084
Echinococcus granulosus neuropeptides capa receptor 0.0932 0.7396 0.7396
Brugia malayi RNA binding protein 0.0061 0.032 0.032
Brugia malayi MAP kinase sur-1 0.0108 0.0697 0.0697
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0026 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0047
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0932 0.7396 0.7396
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0087 0.0261
Leishmania major prostaglandin f synthase, putative 0.0276 0.2061 0.6172
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0098 0.0619 0.0619
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0026 0.0028 0.0129
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0276 0.2061 0.2505
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Loa Loa (eye worm) hypothetical protein 0.0252 0.1871 0.1871
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0026 0.0028 0.0129
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.1252 1 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.0349
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0459 0.0459
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0189 0.1357 0.1357
Schistosoma mansoni myosin xvIII 0.0932 0.7396 0.7396
Brugia malayi hypothetical protein 0.0252 0.1871 0.1871
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0089 0.0545 0.0515
Brugia malayi hypothetical protein 0.0088 0.0533 0.0533
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0097 0.0463
Loa Loa (eye worm) animal heme peroxidase 0.0088 0.0533 0.0533
Trichomonas vaginalis esterase, putative 0.0038 0.0127 0.0155
Mycobacterium leprae Conserved hypothetical protein 0.0162 0.1136 0.5448
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.0697 0.2088
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Loa Loa (eye worm) inositol-1 0.0038 0.0129 0.0129
Schistosoma mansoni biogenic amine (5HT) receptor 0.0932 0.7396 0.7396
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0932 0.7396 0.7396
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0433 0.334 1
Schistosoma mansoni hypothetical protein 0.0022 0.0002 0.0002
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0057 0.0287 0.0287
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0382 0.0382
Onchocerca volvulus 0.0276 0.2061 0.2387
Schistosoma mansoni potassium channel beta 0.0114 0.0746 0.0746
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0114 0.0746 0.2234
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0047
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0129 0.0387
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.2534 0.7589
Brugia malayi beta-lactamase family protein 0.0038 0.0127 0.0127
Plasmodium vivax aldehyde reductase, putative 0.0114 0.0746 0.2234
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0097 0.0339
Brugia malayi hypothetical protein 0.011 0.0715 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0287 0.086
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0057 0.0287 0.086
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.0715 0.0715
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0026 0.0028 0.0129
Toxoplasma gondii aldose reductase, putative 0.0276 0.2061 0.6172
Schistosoma mansoni peroxidasin 0.0088 0.0533 0.0533
Leishmania major cAMP-specific phosphodiesterase, putative 0.0057 0.0287 0.086
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0002 0.0002
Onchocerca volvulus 0.0043 0.0167 0.0049
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0081 0.0081
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0075 0.5
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0127 0.0611
Echinococcus granulosus biogenic amine 5HT receptor 0.0932 0.7396 0.7396
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0075 0.1007
Onchocerca volvulus 0.0932 0.7396 0.8973
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0811 0.0811
Mycobacterium ulcerans 6-phosphofructokinase 0.0116 0.0763 0.3697
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0225 0.0674
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0087 0.0261
Brugia malayi ORL1-like opioid receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Toxoplasma gondii aldo-keto reductase 0.0114 0.0746 0.2234
Mycobacterium ulcerans hypothetical protein 0.0176 0.125 0.6062
Plasmodium falciparum importin beta, putative 0.003 0.0064 0.0863
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0064 0.0193
Entamoeba histolytica hypothetical protein 0.0024 0.0018 0.0083
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0028 0.0084
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0287 0.0349
Loa Loa (eye worm) hypothetical protein 0.0085 0.0514 0.0514
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.1252 1 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0098 0.0292
Onchocerca volvulus 0.0932 0.7396 0.8973
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni rab6-interacting 0.0043 0.0167 0.0167
Echinococcus multilocularis adenylate cyclase type IX 0.0125 0.0838 0.0838
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Schistosoma mansoni neuropeptide F-like receptor 0.0932 0.7396 0.7396
Brugia malayi Cytochrome P450 family protein 0.0034 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Mycobacterium tuberculosis Conserved protein 0.0038 0.0127 0.0611
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0075 0.0091
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0465 0.0565
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0117 0.0775 0.2322
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0237 0.1745 0.1745
Echinococcus multilocularis GPCR, family 2 0.0032 0.0081 0.0081
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0276 0.2061 0.6172
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0087 0.0261
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0114 0.0746 0.0746
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.0349
Schistosoma mansoni microtubule-associated protein tau 0.0755 0.596 0.596
Schistosoma mansoni neuropeptide receptor 0.0932 0.7396 0.7396
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0811 0.3928
Schistosoma mansoni biogenic amine receptor 0.0932 0.7396 0.7396
Mycobacterium ulcerans lipase LipD 0.0038 0.0127 0.0611
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0002 0.0005
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0811 0.2427
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.0697 0.2088
Echinococcus multilocularis lamin 0.006 0.0307 0.0307
Echinococcus multilocularis neuropeptide receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0167 0.0167
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0932 0.7396 0.7396
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Onchocerca volvulus 0.0932 0.7396 0.8973
Brugia malayi 6-phosphofructokinase 0.0116 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Giardia lamblia hypothetical protein 0.0057 0.0287 0.1298
Loa Loa (eye worm) intermediate filament protein 0.006 0.0307 0.0307
Schistosoma mansoni hypothetical protein 0.0032 0.0081 0.0081
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0026 0.0028 0.0129
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Onchocerca volvulus 0.0088 0.0533 0.0501
Mycobacterium tuberculosis Probable oxidoreductase 0.0276 0.2061 1
Plasmodium falciparum aldo-keto reductase, putative 0.0114 0.0746 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.0697 0.0697
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Onchocerca volvulus 0.0043 0.0167 0.0049
Echinococcus granulosus alpha 1A adrenergic receptor 0.0932 0.7396 0.7396
Brugia malayi jmjC domain containing protein 0.0062 0.0327 0.0327
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0075 0.0091
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0002 0.0002
Onchocerca volvulus Peroxidase homolog 0.0088 0.0533 0.0501
Loa Loa (eye worm) melatonin receptor type 1A 0.0932 0.7396 0.7396
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0697 0.2088
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0081 0.0081
Brugia malayi hypothetical protein 0.0032 0.0082 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0697 0.0848
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0932 0.7396 0.7396
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0081 0.0081
Trichomonas vaginalis aldo-keto reductase, putative 0.0114 0.0746 0.0907
Brugia malayi beta-lactamase family protein 0.0038 0.0127 0.0127
Brugia malayi hypothetical protein 0.0043 0.0167 0.0167
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0935 0.7425 0.7425
Brugia malayi Animal haem peroxidase family protein 0.0088 0.0533 0.0533
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0276 0.2061 0.2505
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0028 0.0129
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.0715 0.0715
Echinococcus granulosus snurportin 1 0.032 0.2423 0.2423
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0089 0.0545 0.0545
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0202 0.0605
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0932 0.7396 0.7396
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0225 0.302
Loa Loa (eye worm) RNA binding protein 0.0061 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0079 0.0465 0.0465
Brugia malayi hypothetical protein 0.0188 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.0029 0.0055 0.0055
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.0989 0.4794
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0129 0.0129
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.0989 0.4794
Loa Loa (eye worm) hypothetical protein 0.0088 0.0533 0.0533
Giardia lamblia DINP protein human, muc B family 0.0022 0.0002 0.0007
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0287 0.0349
Brugia malayi Doublecortin family protein 0.0043 0.0167 0.0167
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0287 0.0287
Trypanosoma brucei aldo-keto reductase, putative 0.0276 0.2061 0.6172
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0327 0.0327
Onchocerca volvulus Chorion peroxidase homolog 0.0088 0.0533 0.0501
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Loa Loa (eye worm) hypothetical protein 0.0101 0.0642 0.0642
Brugia malayi RNA, U transporter 1 0.0085 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Echinococcus granulosus hypothetical protein 0.0276 0.2061 0.2061
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.1105 0.3309
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0028 0.0084
Brugia malayi Pre-SET motif family protein 0.0908 0.7207 0.7207
Echinococcus granulosus aldo keto reductase 0.0276 0.2061 0.2061
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.0697 0.2088
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.1105 0.3309
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0309 0.0375
Echinococcus multilocularis neuropeptide FF receptor 2 0.0932 0.7396 0.7396
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Echinococcus multilocularis fmrfamide receptor 0.0932 0.7396 0.7396
Plasmodium vivax SET domain protein, putative 0.013 0.088 0.2635
Schistosoma mansoni aldo-keto reductase 0.0276 0.2061 0.2061
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0096 0.0598 0.0727
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.013 0.088 0.2635
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Onchocerca volvulus 0.0932 0.7396 0.8973
Loa Loa (eye worm) oxidoreductase 0.0276 0.2061 0.2061
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0087 0.0087
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0087 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0061 0.032 0.032
Mycobacterium ulcerans putative regulatory protein 0.0042 0.0158 0.0761
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0081 0.0081
Mycobacterium tuberculosis Conserved protein 0.0038 0.0127 0.0611
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0167 0.0167
Onchocerca volvulus 0.0932 0.7396 0.8973
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0276 0.2061 1
Onchocerca volvulus 0.0276 0.2061 0.2387
Schistosoma mansoni neuropeptide receptor 0.0932 0.7396 0.7396
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0075 0.0225
Loa Loa (eye worm) acetyltransferase 0.0299 0.2251 0.2251
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0057 0.0287 0.0287
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0697 0.0848
Echinococcus granulosus sex peptide receptor 0.0932 0.7396 0.7396
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0055 0.0055
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0932 0.7396 0.7396
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0932 0.7396 0.7396
Schistosoma mansoni biogenic amine (5HT) receptor 0.0932 0.7396 0.7396
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0064
Brugia malayi Tachykinin-like peptides receptor 99D 0.0932 0.7396 0.7396
Echinococcus granulosus biogenic amine 5HT receptor 0.0932 0.7396 0.7396
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0763 0.3449
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0167 0.0167
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0117 0.0775 0.2322
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0075 0.0225
Schistosoma mansoni pol-related 0.0276 0.2061 0.2061
Loa Loa (eye worm) hypothetical protein 0.0069 0.0382 0.0382
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0075 0.0225
Echinococcus granulosus survival motor neuron protein 1 0.0252 0.1871 0.1871
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0028 0.0129
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.0763 0.0763
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0811 0.2427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Loa Loa (eye worm) neuropeptide F receptor 0.0932 0.7396 0.7396
Echinococcus granulosus neuropeptides capa receptor 0.0932 0.7396 0.7396
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0114 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0057 0.0287 0.0287
Onchocerca volvulus 0.0932 0.7396 0.8973
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0932 0.7396 0.7396
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0276 0.2061 0.2061
Echinococcus multilocularis dro:myosuppressin receptor 0.0932 0.7396 0.7396
Schistosoma mansoni amine GPCR 0.0932 0.7396 0.7396
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0026 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Schistosoma mansoni rab6-interacting 0.0043 0.0167 0.0167
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0026 0.0028 0.0129
Schistosoma mansoni biogenic amine receptor 0.0932 0.7396 0.7396
Echinococcus granulosus rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Onchocerca volvulus 0.0089 0.0545 0.0515
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0127
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Mycobacterium tuberculosis Conserved protein 0.0114 0.0746 0.3615
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0127 0.0155
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0055 0.0055
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0127 0.0611
Echinococcus granulosus 6 phosphofructokinase 0.0116 0.0763 0.0763
Brugia malayi Melatonin receptor type 1A 0.0932 0.7396 0.7396
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0287 0.086
Echinococcus granulosus aldo keto reductase 0.0276 0.2061 0.2061
Schistosoma mansoni amine GPCR 0.0932 0.7396 0.7396
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0811 0.0811
Brugia malayi Cytochrome P450 family protein 0.0064 0.034 0.034
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0167 0.0167
Onchocerca volvulus Dual oxidase homolog 0.0088 0.0533 0.0501
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0276 0.2061 0.2061
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0018 0.0055
Echinococcus granulosus neuropeptide receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0117 0.0775 0.0943
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0932 0.7396 0.7396
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0117 0.0775 0.0775
Echinococcus granulosus neuropeptide receptor A26 0.0932 0.7396 0.7396
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0932 0.7396 0.8973
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0287 0.0287
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0932 0.7396 0.7396
Onchocerca volvulus 0.0932 0.7396 0.8973
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0057 0.0287 0.0287
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0237 0.1745 0.1745
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0096 0.0598 0.0727
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0127 0.0155
Echinococcus granulosus neuropeptide Y receptor 0.0932 0.7396 0.7396
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0287 0.0349
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0002 0.0005
Loa Loa (eye worm) adenylyl cyclase 3 0.021 0.1531 0.1531
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0117 0.0775 0.0943
Brugia malayi cytochrome P450 0.0026 0.0028 0.0028
Echinococcus granulosus dna polymerase kappa 0.0022 0.0002 0.0002
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0117 0.0775 0.0943
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0276 0.2061 0.2061
Brugia malayi hypothetical protein 0.0932 0.7396 0.7396
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.0989 0.4726
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Brugia malayi Animal haem peroxidase family protein 0.0088 0.0533 0.0533
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0287 0.086
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0028 0.0129
Schistosoma mansoni amine GPCR 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0167
Brugia malayi Dopamine receptor protein 2 0.0932 0.7396 0.7396
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0932 0.7396 0.7396
Loa Loa (eye worm) PDE1B protein 0.1252 1 1
Echinococcus multilocularis g protein coupled receptor 0.0932 0.7396 0.7396
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0026 0.0028 0.0129
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2212 0.2689
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0932 0.7396 0.7396
Schistosoma mansoni hypothetical protein 0.036 0.2746 0.2746
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0237 0.1745 0.1745
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0088 0.0535 0.1603
Trichomonas vaginalis aldo-keto reductase, putative 0.0276 0.2061 0.2505
Echinococcus multilocularis rhodopsin orphan GPCR 0.0932 0.7396 0.7396
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0287 0.0349
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0276 0.2061 0.2061
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0775 0.0943
Brugia malayi hypothetical protein 0.005 0.0225 0.0225
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0081 0.0081
Brugia malayi Pre-SET motif family protein 0.013 0.088 0.088
Entamoeba histolytica alcohol dehydrogenase, putative 0.0114 0.0746 0.3372
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.0763 0.2284
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0697 0.0848
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0932 0.7396 0.7396
Loa Loa (eye worm) hypothetical protein 0.006 0.0307 0.0307
Echinococcus granulosus RUN 0.0043 0.0167 0.0167
Schistosoma mansoni hypothetical protein 0.0932 0.7396 0.7396
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0002 0.0002
Echinococcus granulosus 7tm_1 domain containing protein 0.0932 0.7396 0.7396
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0116 0.0763 0.3697
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0225 0.0674
Trypanosoma brucei prostaglandin f synthase 0.0276 0.2061 0.6172
Loa Loa (eye worm) oxidoreductase 0.0276 0.2061 0.2061
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0057 0.0287 0.0287
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0002 0.0005
Loa Loa (eye worm) G-protein coupled receptor 0.0932 0.7396 0.7396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0932 0.7396 0.7396
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0098 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0309 0.0375
Trichomonas vaginalis bromodomain-containing protein, putative 0.0088 0.0535 0.0651
Toxoplasma gondii hypothetical protein 0.006 0.0309 0.0925
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0088 0.0535 0.0651
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0028 0.0084
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0114 0.0746 0.0907
Brugia malayi beta-lactamase 0.0038 0.0127 0.0127
Echinococcus multilocularis serotonin receptor 0.0932 0.7396 0.7396
Schistosoma mansoni transcription factor LCR-F1 0.011 0.0715 0.0715
Giardia lamblia Hypothetical protein 0.0057 0.0287 0.1298
Echinococcus granulosus Solute carrier family 22 5 0.1162 0.9272 0.9272
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0064 0.0193
Schistosoma mansoni lipoxygenase 0.0112 0.0734 0.0734
Schistosoma mansoni aldo-keto reductase 0.0276 0.2061 0.2061
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0075 0.1007
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0075 0.0091
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0167 0.2239
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.2423 0.2423
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.0763 0.0763

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 7.18 Mean binding affinity for human H3 receptor ChEMBL. 15771465
Log Ki (binding) = 7.18 Mean binding affinity for human H3 receptor ChEMBL. 15771465

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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