Detailed information for compound 401321

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1020.2 | Formula: C51H69N7O13S
  • H donors: 9 H acceptors: 11 LogP: 6.11 Rotable bonds: 37
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCC[C@@H](C(=O)N[C@@H](CC(=O)O)CCCOc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2c1cccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)S(=O)(=O)O)NC(=O)OC(C)(C)C)CCCC
  • InChi: 1S/C51H69N7O13S/c1-6-8-20-40(56-48(64)42(58-50(66)71-51(3,4)5)28-33-23-25-37(26-24-33)72(67,68)69)46(62)53-32-44(59)55-43(29-34-31-52-39-22-14-13-19-38(34)39)49(65)57-41(21-9-7-2)47(63)54-35(30-45(60)61)16-15-27-70-36-17-11-10-12-18-36/h10-14,17-19,22-26,31,35,40-43,52H,6-9,15-16,20-21,27-30,32H2,1-5H3,(H,53,62)(H,54,63)(H,55,59)(H,56,64)(H,57,65)(H,58,66)(H,60,61)(H,67,68,69)/t35-,40+,41+,42+,43-/m1/s1
  • InChiKey: CWCIEGCNXSWALH-KHSZCUONSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Trypanosoma cruzi cysteine peptidase, putative Curated by TDR Targets References
Homo sapiens cholecystokinin B receptor Starlite/ChEMBL References
Homo sapiens amylase, alpha 2A (pancreatic) Starlite/ChEMBL References
Rattus norvegicus Cholecystokinin B receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis alpha-amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica alpha-amylase family protein Get druggable targets OG5_128640 All targets in OG5_128640
Trichomonas vaginalis alpha-amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis alpha-amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis alpha-amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica alpha-amylase family protein Get druggable targets OG5_128640 All targets in OG5_128640
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis alpha-amylase, putative Get druggable targets OG5_128640 All targets in OG5_128640
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein Cholecystokinin B receptor   452 aa 389 aa 31.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.002 0.0022 0.0209
Onchocerca volvulus 0.0102 0.0305 0.2963
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0001 0.0006
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0075 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1006 0.4314
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0017 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.0944 0.405
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0316 0.1353
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.0305 0.0988
Trichomonas vaginalis alpha-amylase, putative 0.0129 0.0396 0.1696
Onchocerca volvulus 0.002 0.0022 0.0209
Onchocerca volvulus 0.002 0.0022 0.0209
Echinococcus multilocularis survival motor neuron protein 1 0.0459 0.1529 0.1528
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0076 0.0075
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0347 0.1144 0.4908
Trypanosoma brucei protein kinase, putative 0.005 0.0123 0.0938
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.0305 0.0304
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0151 0.0472 0.1363
Schistosoma mansoni amine GPCR 0.0102 0.0305 0.0873
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0217 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0132 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0018 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0074 0.0207 0.0669
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0074 0.0207 0.0206
Onchocerca volvulus 0.0102 0.0305 0.2963
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0042 0.0135
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0074 0.0207 0.1936
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0305 0.0873
Brugia malayi Cathepsin L-like precursor 0.002 0.0022 0.0092
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0022 0.007
Brugia malayi Protein kinase domain containing protein 0.0017 0.0012 0.0049
Schistosoma mansoni alpha-amylase 0.0014 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0337 0.1112 0.3236
Echinococcus multilocularis expressed conserved protein 0.0079 0.0225 0.0225
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0075 0.0202
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0051 0.0213
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0065 0.0175 0.0566
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0115 0.0329
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.019 0.0605 0.1963
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0052 0.0146
Brugia malayi hypothetical protein 0.0035 0.0073 0.0311
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0102 0.0305 0.1306
Echinococcus granulosus fmrfamide receptor 0.0102 0.0305 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.1082 0.4644
Leishmania major cathepsin L-like protease 0.0077 0.0217 0.0575
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0074 0.0207 0.0882
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus granulosus lamin dm0 0.0026 0.0042 0.0041
Schistosoma mansoni hypothetical protein 0.0074 0.0207 0.0591
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0017 0.0016
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0051 0.0477
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0031 0.0131
Brugia malayi Serotonin receptor 0.0102 0.0305 0.1306
Schistosoma mansoni opsin-like receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0311 0.1021 0.4381
Toxoplasma gondii hypothetical protein 0.0019 0.0018 0.0166
Toxoplasma gondii Alpha-amylase AMY3, putative 0.0014 0.0001 0.0011
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0157 0.1236
Brugia malayi hypothetical protein 0.0098 0.0289 0.1239
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0067
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0151 0.0472 0.4426
Loa Loa (eye worm) hypothetical protein 0.0048 0.0118 0.0382
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0008 0.0022
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0059 0.0157 0.0448
Trypanosoma cruzi hypothetical protein, conserved 0.101 0.3425 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0187 0.0594 0.1719
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trichomonas vaginalis amylase, putative 0.0057 0.015 0.0637
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0151 0.0472 0.2023
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0151 0.0472 0.0471
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0074 0.0207 0.1678
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0016 0.0008 0.0008
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0151 0.0472 0.1363
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0017 0.0016
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.004 0.0092 0.0389
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Toxoplasma gondii alpha amylase, catalytic domain-containing protein 0.0057 0.015 0.1402
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.013
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0075 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.0185 0.0789
Giardia lamblia Kinase, PLK 0.0187 0.0594 0.4336
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.0305 0.0988
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0048 0.0047
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0017 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0351 0.1502
Brugia malayi larval opioid receptor 0.0102 0.0305 0.1306
Onchocerca volvulus Cathepsin L homolog 0.002 0.0022 0.0209
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.0018 0.0524
Trichomonas vaginalis alpha-amylase, putative 0.0129 0.0396 0.1696
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Brugia malayi G protein-coupled receptor 0.0102 0.0305 0.1306
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0076 0.0075
Brugia malayi Tachykinin-like peptides receptor 99D 0.0102 0.0305 0.1306
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0102 0.0305 0.0304
Entamoeba histolytica serine/threonine protein kinase, putative 0.0187 0.0594 0.2545
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0074 0.0207 0.0206
Loa Loa (eye worm) hypothetical protein 0.0173 0.0546 0.1772
Leishmania major hypothetical protein, conserved 0.1084 0.3678 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Plasmodium vivax vivapain-2 0.002 0.0022 0.0458
Brugia malayi Serotonin receptor 0.055 0.1843 0.7913
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0084 0.0242 0.0242
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0074 0.0207 0.0884
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0001 0.000000035814
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0075 0.0512
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.0305 0.0304
Trypanosoma cruzi polo-like protein kinase, putative 0.0187 0.0594 0.1719
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0313 0.1027 1
Echinococcus granulosus expressed conserved protein 0.0079 0.0225 0.0225
Plasmodium falciparum casein kinase 2, alpha subunit 0.0133 0.0411 0.8655
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0022 0.0158
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0075 0.0214
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0024 0.0096
Brugia malayi Cytochrome P450 family protein 0.0019 0.0017 0.0072
Schistosoma mansoni biogenic amine receptor 0.0102 0.0305 0.0873
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0313 0.1027 0.3335
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0133 0.0411 0.1332
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0102 0.0305 0.0304
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0075 0.0242
Plasmodium vivax glycogen synthase kinase 3, putative 0.005 0.0123 0.2599
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0051 0.1067
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0074 0.0207 0.0206
Brugia malayi Cytochrome P450 family protein 0.0019 0.0017 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0028 0.0089
Brugia malayi intracellular kinase 0.005 0.0123 0.0526
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Trichomonas vaginalis set domain proteins, putative 0.0229 0.0739 0.3169
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0102 0.0305 0.1306
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0008 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0051 0.0213
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.0305 0.0873
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0194 0.055
Onchocerca volvulus 0.0102 0.0305 0.2963
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0313 0.1027 0.3335
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0051 0.0213
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0316 0.1353
Brugia malayi Cathepsin L-like precursor 0.002 0.0022 0.0092
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Onchocerca volvulus 0.0048 0.0118 0.1143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.1082 0.4644
Echinococcus multilocularis g-protein coupled receptor 0.0102 0.0305 0.0304
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0074 0.0207 0.0591
Onchocerca volvulus 0.0102 0.0305 0.2963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0684 0.2933
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0337 0.1112 0.3192
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0316 0.1353
Loa Loa (eye worm) melatonin receptor type 1A 0.0102 0.0305 0.0988
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0017 0.0046
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.0644 0.2089
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0052 0.0146
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0102 0.0305 0.0304
Onchocerca volvulus 0.0102 0.0305 0.2963
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.0305 0.0873
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0316 1
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0051 0.0477
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0217 0.0618
Schistosoma mansoni voltage-gated cation channel 0.0036 0.0076 0.0217
Schistosoma mansoni alpha-amylase 0.0014 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0102 0.0305 0.0304
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0017 0.0016
Entamoeba histolytica hypothetical protein 0.0035 0.0073 0.0308
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0046 0.0112 0.0363
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0075 0.1318
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0008 0.0022
Echinococcus multilocularis neuropeptide FF receptor 2 0.0102 0.0305 0.0304
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0036 0.0076 0.0075
Brugia malayi Cytochrome P450 family protein 0.0029 0.0052 0.0221
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0017 0.0016
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0329 0.1083 0.9456
Echinococcus multilocularis orexin receptor type 2 0.0102 0.0305 0.0304
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0316 0.0315
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0173 0.0546 0.2341
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0052 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0174 0.055 0.2361
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0195 0.0624 0.1806
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0046
Giardia lamblia GTOR 0.0347 0.1144 0.8729
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0316 0.1025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0074 0.0207 0.4367
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0067
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0024 0.0096
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0022 0.009
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0022 0.009
Leishmania major hypothetical protein, unknown function 0.0074 0.0207 0.0545
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0151 0.0472 0.2025
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0073 0.0207
Schistosoma mansoni amine GPCR 0.0102 0.0305 0.0873
Brugia malayi hypothetical protein 0.0159 0.0499 0.2138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0102 0.0305 0.0304
Onchocerca volvulus 0.0229 0.0739 0.7198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0208 0.0669 0.2867
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0116 0.0351 0.035
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0074 0.0207 0.419
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0074 0.0207 0.0206
Schistosoma mansoni alpha-1 adrenergic receptor 0.0102 0.0305 0.0873
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0187 0.0595 0.5126
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0313 0.1027 0.1026
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0123 0.0398
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0174 0.055 0.1787
Echinococcus granulosus glycogen synthase kinase 3 beta 0.005 0.0123 0.0122
Schistosoma mansoni hypothetical protein 0.0094 0.0274 0.0785
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0305 0.0304
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1005 0.4313
Echinococcus granulosus g protein coupled receptor 0.0102 0.0305 0.0304
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0024 0.0023
Toxoplasma gondii hypothetical protein 0.0052 0.0132 0.1234
Brugia malayi phosphofructokinase 0.0106 0.0316 0.1355
Loa Loa (eye worm) phosphatidylinositol 3 0.0074 0.0207 0.0669
Leishmania major cathepsin L-like protease 0.0077 0.0217 0.0575
Loa Loa (eye worm) hypothetical protein 0.0074 0.0207 0.0669
Brugia malayi Melatonin receptor type 1A 0.0102 0.0305 0.1306
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0022 0.0021
Echinococcus granulosus intermediate filament protein 0.0026 0.0042 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.0305 0.0304
Leishmania major phosphatidylinositol kinase, putative 0.0074 0.0207 0.0545
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.1082 0.4644
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0075 0.1582
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0016 0.0008 0.0008
Giardia lamblia 1,4-alpha-glucan branching enzyme 0.0057 0.015 0.0788
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0151 0.0472 0.1269
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0123 0.0524
Brugia malayi hypothetical protein 0.0459 0.1529 0.6561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0187 0.0595 0.255
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.007
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Onchocerca volvulus Cathepsin F homolog 0.002 0.0022 0.0209
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0456 0.148
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0347 0.1144 1
Plasmodium vivax SET domain protein, putative 0.0029 0.0052 0.1086
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0269 0.0877 0.7634
Onchocerca volvulus 0.0102 0.0305 0.2963
Leishmania major phosphatidylinositol 3-kinase, putative 0.0151 0.0472 0.1269
Leishmania major cytochrome p450-like protein 0.0019 0.0017 0.0031
Toxoplasma gondii target of rapamycin (TOR), putative 0.0324 0.1067 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.1082 0.4644
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0075 0.0725
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0123 0.0398
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0692 0.233 0.6797
Entamoeba histolytica alpha-amylase family protein 0.0129 0.0396 0.1696
Toxoplasma gondii non-specific serine/threonine protein kinase 0.019 0.0605 0.5668
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0014 0.0001 0.0002
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0251 0.025
Schistosoma mansoni serine/threonine protein kinase 0.013 0.04 0.1147
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0305 0.0304
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0347 0.1144 0.3328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1006 0.4314
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0008 0.0022
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0151 0.0472 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Brugia malayi Cathepsin L-like precursor 0.002 0.0022 0.0092
Schistosoma mansoni hypothetical protein 0.0116 0.0351 0.1005
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0692 0.233 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0028 0.0118
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0057 0.015 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0028 0.0078
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0043 0.0179
Entamoeba histolytica hypothetical protein 0.0035 0.0073 0.0308
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0102 0.0305 0.0304
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Brugia malayi RE15519p 0.0102 0.0305 0.1306
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0043 0.0179
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0157 0.044
Echinococcus multilocularis tumor protein p63 0.0329 0.1083 0.1082
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0102 0.0305 0.0304
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.011 0.0329 0.2768
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0102 0.0305 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0028 0.0027
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0183 0.0582 0.2494
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0042 0.0178
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0022 0.009
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0017 0.0046
Trichomonas vaginalis alpha-amylase, putative 0.0129 0.0396 0.1696
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0036 0.0076 0.0217
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Brugia malayi G protein-coupled receptor F59B2.13 0.0102 0.0305 0.1306
Brugia malayi G-protein coupled receptor 0.0102 0.0305 0.1306
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.000000012475
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0305 0.0304
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0075 0.0074
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0269 0.0877 0.3763
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0102 0.0305 0.0304
Brugia malayi follicle stimulating hormone receptor 0.0326 0.1074 0.4609
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0289 0.0944 0.8226
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0074 0.0207 0.1936
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0347 0.1144 0.1143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0031 0.003
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0511 0.1708 0.7332
Trypanosoma brucei Casein kinase II 0.0133 0.0411 0.3491
Onchocerca volvulus Cathepsin L homolog 0.002 0.0022 0.0209
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0574 0.1924 0.826
Echinococcus granulosus serine protein kinase ATM 0.0187 0.0595 0.0594
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0102 0.0305 0.0304
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0187 0.0595 0.1722
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0001 0.0006
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0269 0.0877 0.3763
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0157 0.0668
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0102 0.0305 0.0873
Brugia malayi hypothetical protein 0.0019 0.0017 0.0069
Echinococcus multilocularis neuropeptide receptor 0.0102 0.0305 0.0304
Brugia malayi Csnk2b protein 0.0036 0.0075 0.032
Echinococcus granulosus hypothetical protein 0.0102 0.0305 0.0304
Brugia malayi putative neuropeptide receptor NPR1 0.0102 0.0305 0.1306
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0275 0.1175
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0173 0.0546 0.1579
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0017 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0305 0.0304
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0036 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0074 0.0207 0.0882
Echinococcus granulosus tumor protein p63 0.0329 0.1083 0.1082
Leishmania major cathepsin L-like protease 0.002 0.0022 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0031 0.0087
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0305 0.0304
Schistosoma mansoni starch branching enzyme II 0.0057 0.015 0.0427
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Schistosoma mansoni hypothetical protein 0.0102 0.0305 0.0873
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0052
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0316 0.0906
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0347 0.1144 0.1143
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus multilocularis cysteine protease 0.002 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0052
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0017 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1005 0.4313
Loa Loa (eye worm) phosphatidylinositol 3 0.0074 0.0207 0.0669
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0102 0.0305 0.2963
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0067
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.0305 0.0304
Echinococcus granulosus neuropeptide receptor A26 0.0102 0.0305 0.0304
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0102 0.0305 0.0304
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Entamoeba histolytica hypothetical protein 0.0035 0.0073 0.0308
Schistosoma mansoni myosin xvIII 0.0102 0.0305 0.0873
Schistosoma mansoni hypothetical protein 0.0079 0.0225 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0347 0.1144 0.4908
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0022 0.007
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0157 0.0156
Trypanosoma brucei polo-like protein kinase 0.0187 0.0594 0.5116
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0337 0.1112 0.3236
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0018 0.0061
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0051 0.3349
Leishmania major cathepsin L-like protease 0.002 0.0022 0.0043
Loa Loa (eye worm) phosphatidylinositol 3 0.0074 0.0207 0.0669
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0022 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Mycobacterium tuberculosis 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) 0.0057 0.015 0.4712
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Onchocerca volvulus 0.0102 0.0305 0.2963
Brugia malayi Cathepsin L-like precursor 0.002 0.0022 0.0092
Echinococcus granulosus peptide allatostatin:somatostatin 0.0102 0.0305 0.0304
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Schistosoma mansoni neuropeptide receptor 0.0102 0.0305 0.0873
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.0305 0.0304
Schistosoma mansoni hypothetical protein 0.005 0.0124 0.0355
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Schistosoma mansoni intermediate filament proteins 0.0026 0.0042 0.0119
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0692 0.233 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0316 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0008 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0166
Brugia malayi hypothetical protein 0.0019 0.0017 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0133 0.0411 0.1759
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0008 0.0031
Loa Loa (eye worm) hypothetical protein 0.0159 0.0499 0.1618
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0017 0.0016
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0251 0.0719
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0075 0.0318
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0187 0.0594 0.1927
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0031 0.003
Brugia malayi M-phase phosphoprotein, mpp8 0.0098 0.0289 0.1238
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0074 0.0207 0.0586
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0017 0.0067
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0316 0.0906
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0052 0.0167
Loa Loa (eye worm) gastrulation defective protein 1 0.0127 0.0389 0.1261
Onchocerca volvulus 0.0074 0.0207 0.2005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0231 0.0746 0.3198
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0051 0.0213
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0074 0.0207 0.0884
Schistosoma mansoni hypothetical protein 0.0102 0.0305 0.0873
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.0098 0.0289 0.0938
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0017 0.0033
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0347 0.1144 0.3328
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Loa Loa (eye worm) phosphatidylinositol 3 0.091 0.3078 1
Schistosoma mansoni alpha-amylase 0.0014 0.0001 0.0001
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0057 0.015 0.0149
Echinococcus granulosus bloom syndrome protein 0.0021 0.0024 0.0023
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0208 0.0666 0.5759
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus granulosus alpha 1A adrenergic receptor 0.0102 0.0305 0.0304
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0074 0.0207 0.0591
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.0067
Plasmodium vivax vivapain-2 0.002 0.0022 0.0458
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0199 0.0198
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.004 0.0092 0.0389
Echinococcus multilocularis dro:myosuppressin receptor 0.0102 0.0305 0.0304
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.0305 0.0873
Leishmania major phosphatidylinositol kinase related protein, putative 0.0088 0.0255 0.0679
Plasmodium vivax unspecified product 0.0133 0.0411 0.8696
Brugia malayi Dopamine receptor 0.0102 0.0305 0.1306
Plasmodium vivax hypothetical protein 0.0074 0.0207 0.4367
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0074 0.0207 0.0206
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0173 0.0546 0.0545
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0018 0.0166
Toxoplasma gondii hypothetical protein 0.0019 0.0018 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0292 0.1249
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0043
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Entamoeba histolytica hypothetical protein 0.0074 0.0207 0.0882
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0051 0.0213
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.0185 0.0789
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0075 0.0074
Schistosoma mansoni alpha-amylase 0.0014 0.0001 0.0001
Echinococcus granulosus g-protein coupled receptor 0.0102 0.0305 0.0304
Echinococcus granulosus cathepsin l1 0.002 0.0022 0.0021
Brugia malayi 6-phosphofructokinase 0.0106 0.0316 0.1355
Schistosoma mansoni hypothetical protein 0.0035 0.0073 0.0207
Toxoplasma gondii FATC domain-containing protein 0.0187 0.0595 0.5576
Echinococcus multilocularis neuropeptide receptor A26 0.0102 0.0305 0.0304
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0313 0.1027 0.1026
Brugia malayi Cyclic-nucleotide gated cation channel 0.0016 0.0008 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0018 0.0363
Brugia malayi SH2 domain containing protein 0.0331 0.109 0.4676
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.005 0.0123 0.1154
Brugia malayi AKH receptor 0.0102 0.0305 0.1306
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0347 0.1144 0.4908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0347 0.1144 0.4908
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Leishmania major phosphatidylinositol 3-kinase, putative 0.0289 0.0944 0.2554
Onchocerca volvulus 0.004 0.009 0.0866
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0393 0.1303 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0074 0.0207 0.0884
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0042 0.0135
Entamoeba histolytica cysteine protease, putative 0.002 0.0022 0.009
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.0305 0.0304
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0074 0.0208 0.0889
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0051 0.0787
Loa Loa (eye worm) phosphatidylinositol kinase 0.0074 0.0207 0.0669
Loa Loa (eye worm) alpha amylase 0.0014 0.0001 0.0002
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0199 0.0198
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0051 0.3349
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0022 0.0021
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0009 0.0023
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Echinococcus multilocularis serine protein kinase ATM 0.0187 0.0595 0.0594
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0076 0.0075
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0074 0.0207 0.0591
Echinococcus multilocularis neuropeptide receptor 0.0102 0.0305 0.0304
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0161 0.0452
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0269 0.0877 0.3765
Trichomonas vaginalis amylase, putative 0.0129 0.0396 0.1696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.0944 0.405
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.0305 0.0988
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0692 0.233 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus granulosus 7TM GPCR rhodopsin 0.0102 0.0305 0.0304
Onchocerca volvulus 0.0102 0.0305 0.2963
Echinococcus granulosus expressed protein 0.0363 0.1201 0.12
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.0305 0.0873
Onchocerca volvulus 0.0102 0.0305 0.2963
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0151 0.0472 0.2023
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus granulosus lamin 0.0026 0.0042 0.0041
Echinococcus multilocularis neuropeptide s receptor 0.0102 0.0305 0.0304
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0073 0.0072
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1006 0.4314
Echinococcus granulosus dro:myosuppressin receptor 0.0102 0.0305 0.0304
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0075 0.1318
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0157 0.044
Onchocerca volvulus 0.0026 0.0042 0.0404
Loa Loa (eye worm) RecQ helicase 0.0021 0.0024 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0017 0.0016
Brugia malayi Protein kinase domain containing protein 0.013 0.04 0.1715
Schistosoma mansoni single-minded 0.0047 0.0115 0.0329
Brugia malayi PXA domain containing protein 0.002 0.0022 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0347 0.1144 0.4908
Toxoplasma gondii CMGC kinase, CK2 family 0.0133 0.0411 0.3849
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0135
Loa Loa (eye worm) phosphatidylinositol 3 0.0299 0.098 0.3182
Brugia malayi PXA domain containing protein 0.002 0.0022 0.009
Brugia malayi neuropeptide F receptor 0.0102 0.0305 0.1306
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0269 0.0877 0.2548
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0026 0.0043 0.0121
Giardia lamblia Kinase, CMGC GSK 0.005 0.0123 0.0577
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.0305 0.0304
Brugia malayi Pre-SET motif family protein 0.0201 0.0644 0.2761
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0151 0.0472 0.0471
Echinococcus multilocularis G protein coupled receptor 139 0.0102 0.0305 0.0304
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0067
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus multilocularis somatostatin receptor 0.0102 0.0305 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Trichomonas vaginalis amylase, putative 0.0129 0.0396 0.1696
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0017 0.0517
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0157 0.1236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1006 0.4314
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0051 0.0787
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0316 0.1353
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0017 0.0052
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0316 0.0844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0031 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0132 0.056
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus multilocularis serotonin receptor 0.0102 0.0305 0.0304
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0017 0.0069
Schistosoma mansoni lamin 0.0026 0.0042 0.0119
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.0305 0.0304
Schistosoma mansoni histamine h1 receptor 0.0102 0.0305 0.0873
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0075 0.0725
Entamoeba histolytica hypothetical protein 0.0074 0.0207 0.0882
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Schistosoma mansoni biogenic amine receptor 0.0102 0.0305 0.0873
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0292 0.1249
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0347 0.1144 0.4909
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0133 0.0411 0.8696
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0102 0.0305 0.1306
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.1005 0.4313
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Echinococcus granulosus single minded 2 0.0042 0.0096 0.0095
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0074 0.0208 0.0207
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0022 0.0021
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0057 0.015 0.0637
Schistosoma mansoni amine GPCR 0.0102 0.0305 0.0873
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0207 0.6518
Echinococcus multilocularis 0.0074 0.0207 0.0206
Echinococcus granulosus G protein coupled receptor 139 0.0102 0.0305 0.0304
Onchocerca volvulus 0.002 0.0022 0.0209
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0332 0.1094 0.4691
Toxoplasma gondii ck2 beta subunit 0.0036 0.0075 0.0705
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0251 0.0719
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0316 0.1037 0.2975
Giardia lamblia Kinase, CMGC GSK 0.005 0.0123 0.0577
Toxoplasma gondii cathepsin CPL 0.002 0.0022 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.1082 0.4644
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0018 0.0524
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0299 0.098 0.2652
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0102 0.0305 0.1306
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0031 0.003
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0014 0.0001 0.0002
Echinococcus multilocularis musashi 0.0026 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.0944 0.405
Schistosoma mansoni protein kinase 0.0133 0.0411 0.1177
Echinococcus granulosus allatostatin A receptor 0.0102 0.0305 0.0304
Onchocerca volvulus 0.0035 0.0073 0.0705
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0017 0.0016
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0076 0.0075
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0074 0.0207 0.4367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0268 0.1145
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0052 0.0051
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0102 0.0305 0.1306
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.0057 0.015 0.0484
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.0305 0.0873
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0008 0.0008
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0173 0.0546 0.0545
Schistosoma mansoni hypothetical protein 0.0102 0.0305 0.0873
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0008 0.0008
Echinococcus multilocularis fmrfamide receptor 0.0102 0.0305 0.0304
Trypanosoma cruzi target of rapamycin kinase 3 0.0329 0.1083 0.3149
Entamoeba histolytica hypothetical protein 0.0035 0.0073 0.0308
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0017 0.0055
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Giardia lamblia Hypothetical protein 0.0074 0.0207 0.1243
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0316 0.1025
Echinococcus granulosus neuropeptide FF receptor 2 0.0102 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus granulosus geminin 0.0164 0.0515 0.0514
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0017 0.0016
Echinococcus multilocularis allatostatin A receptor 0.0102 0.0305 0.0304
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0305 0.0873
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0022 0.0061
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0043 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0183 0.0582 0.2494
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0305 0.0304
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.0018 0.0524
Onchocerca volvulus 0.0102 0.0305 0.2963
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0692 0.233 1
Entamoeba histolytica protein kinase rad3, putative 0.0173 0.0546 0.2339
Schistosoma mansoni opsin-like receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus granulosus protein kinase shaggy 0.005 0.0123 0.0122
Schistosoma mansoni growth hormone secretagogue receptor 0.0102 0.0305 0.0873
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0102 0.0305 0.0873
Echinococcus granulosus g protein coupled receptor 0.0102 0.0305 0.0304
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0051 0.0213
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Entamoeba histolytica hypothetical protein 0.0574 0.1924 0.826
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0074 0.0208 0.0207
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0692 0.233 0.6797
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0026 0.0043 0.0042
Schistosoma mansoni hypothetical protein 0.0164 0.0515 0.1477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0208 0.0669 0.2867
Schistosoma mansoni hypothetical protein 0.0102 0.0305 0.0873
Schistosoma mansoni voltage-gated potassium channel 0.0081 0.023 0.066
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0151 0.0472 0.0471
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0511 0.1708 0.7332
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0187 0.0594 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.1027 0.2947
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0595 0.2552
Echinococcus multilocularis casein kinase ii subunit alpha 0.0133 0.0411 0.041
Toxoplasma gondii glycosyltransferase 0.0057 0.015 0.1402
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0151 0.0472 0.1532
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0251 0.025
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0305 0.0304
Onchocerca volvulus 0.0074 0.0207 0.2005
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0494 0.1651 0.165
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0337 0.1112 0.4773
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0046
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0187 0.0595 0.1706
Echinococcus multilocularis protein kinase shaggy 0.005 0.0123 0.0122
Mycobacterium ulcerans glycogen branching protein 0.0057 0.015 0.4712
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0207 0.0882
Loa Loa (eye worm) TYRA-2 protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) phosphatidylinositol 3 0.0195 0.0624 0.2024
Echinococcus granulosus casein kinase ii subunit alpha 0.0133 0.0411 0.041
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0337 0.1112 0.1112
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0074 0.0207 0.0586
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0008 0.0008
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0336 0.1107 0.4749
Trichomonas vaginalis alpha-amylase, putative 0.0115 0.0348 0.1488
Leishmania major cathepsin L-like protease 0.002 0.0022 0.0043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0102 0.0305 0.0304
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1028 0.3484 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0051 0.1067
Schistosoma mansoni amine GPCR 0.0102 0.0305 0.0873
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0074 0.0207 0.0586
Echinococcus multilocularis serotonin receptor 0.0102 0.0305 0.0304
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0347 0.1144 0.3098
Brugia malayi serine/threonine-protein kinase plk-2 0.0187 0.0594 0.2547
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0075 0.0318
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0187 0.0594 0.0593
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0084 0.0242 0.0242
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0028 0.0027
Brugia malayi Protein kinase domain containing protein 0.0313 0.1027 0.4407
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0036 0.0076 0.0075
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0151 0.0472 0.2023
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0113 0.0341 0.0979
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0017 0.0052
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0017 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0073 0.0072
Loa Loa (eye worm) phosphatidylinositol 3 0.0347 0.1144 0.3715
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Loa Loa (eye worm) hypothetical protein 0.0494 0.1651 0.5361
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Brugia malayi PAS domain containing protein 0.0047 0.0115 0.0493
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0018 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0102 0.0305 0.0873
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0123 0.0524
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0098 0.0289 0.0937
Brugia malayi Death domain containing protein 0.0014 0.0001 0.0001
Echinococcus multilocularis high voltage activated calcium channel beta 0.0084 0.0243 0.0242
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0052 0.0051
Echinococcus multilocularis lamin 0.0026 0.0042 0.0041
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0074 0.0207 0.1936
Schistosoma mansoni biogenic amine receptor 0.0102 0.0305 0.0873
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0025
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0074 0.0207 0.1678
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0242 0.0784 0.2544
Loa Loa (eye worm) cysteine protease 0.002 0.0022 0.007
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0008 0.0025
Onchocerca volvulus 0.0098 0.0289 0.2808
Brugia malayi Casein kinase II, alpha chain 0.0133 0.0411 0.1761
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0008 0.0022
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0016 0.0008 0.0008
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0316 0.0315
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0151 0.0472 0.2023
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0316 0.0907
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0057 0.015 0.0149
Echinococcus granulosus neuropeptide receptor 0.0102 0.0305 0.0304
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.0029 0.0052 0.022
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0102 0.0305 0.0304
Entamoeba histolytica alpha-amylase family protein 0.0129 0.0396 0.1696
Leishmania major cathepsin L-like protease 0.002 0.0022 0.0043
Onchocerca volvulus 0.0098 0.0289 0.2808
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.004 0.0092 0.025
Echinococcus multilocularis expressed protein 0.0363 0.1201 0.12
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0316 0.1353
Brugia malayi hypoxia-induced factor 1 0.0147 0.0456 0.1956
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0207 0.4367
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0102 0.0305 0.0988
Onchocerca volvulus Serine\/threonine kinase homolog 0.0187 0.0594 0.5778
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0594 0.1703
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.0305 0.0304
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0043 0.0179
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0347 0.1144 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0052
Giardia lamblia Kinase, CMGC CK2 0.0133 0.0411 0.2873
Trichomonas vaginalis starch branching enzyme II, putative 0.0057 0.015 0.0637
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Onchocerca volvulus 0.0094 0.0274 0.2664
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Onchocerca volvulus 0.0102 0.0305 0.2963
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0017 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0311 0.1021 0.4381
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0017 0.0046
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0217 0.0618
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0207 0.6518
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0017 0.0016
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0269 0.0877 0.3763
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.009 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Onchocerca volvulus 0.0102 0.0305 0.2963
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0275 0.1175
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0347 0.1144 0.3282
Schistosoma mansoni hypothetical protein 0.0164 0.0515 0.1477
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0102 0.0305 0.0873
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0057 0.015 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0316 0.2652
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0022 0.0021
Schistosoma mansoni neuropeptide receptor 0.0102 0.0305 0.0873
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0073 0.0072
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Leishmania major casein kinase II, putative 0.0133 0.0411 0.1101
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0313 0.1029 0.4415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.0944 0.405
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0337 0.1112 0.1112
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0051 0.0477
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0052 0.0485
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0313 0.1027 0.4407
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1028 0.3484 0.3483
Echinococcus granulosus neuropeptide receptor 0.0102 0.0305 0.0304
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0217 0.0618
Loa Loa (eye worm) ctsf protein 0.002 0.0022 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Leishmania major cathepsin L-like protease 0.0077 0.0217 0.0575
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus multilocularis geminin 0.0164 0.0515 0.0514
Onchocerca volvulus 0.0102 0.0305 0.2963
Echinococcus granulosus orexin receptor type 2 0.0102 0.0305 0.0304
Schistosoma mansoni neuropeptide receptor 0.0102 0.0305 0.0873
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.0018 0.0524
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Brugia malayi FAT domain containing protein 0.0116 0.0351 0.1504
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0316 0.1025
Entamoeba histolytica casein kinase, putative 0.0133 0.0411 0.1759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0208 0.0669 0.2867
Toxoplasma gondii 1,4-alpha-glucan-branching enzyme 0.0057 0.015 0.1402
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0102 0.0305 0.0988
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0329 0.1083 0.2931
Schistosoma mansoni kinase 0.0096 0.0283 0.0811
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0123 0.0524
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0157 0.0668
Schistosoma mansoni neuropeptide f receptor 76f 0.0102 0.0305 0.0873
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.0305 0.0304
Echinococcus granulosus neuropeptide s receptor 0.0102 0.0305 0.0304
Brugia malayi Dopamine receptor protein 2 0.0102 0.0305 0.1306
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0316 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0299 0.098 0.4204
Echinococcus granulosus survival motor neuron protein 1 0.0459 0.1529 0.1528
Onchocerca volvulus 0.002 0.0022 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0022 0.0158
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Entamoeba histolytica protein kinase, putative 0.005 0.0123 0.0524
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Brugia malayi Cathepsin L-like precursor 0.002 0.0022 0.0092
Echinococcus granulosus g protein coupled receptor 0.0102 0.0305 0.0304
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Loa Loa (eye worm) fibroinase 0.002 0.0022 0.007
Loa Loa (eye worm) calcium channel 0.0036 0.0076 0.0246
Echinococcus multilocularis sex peptide receptor 0.0102 0.0305 0.0304
Echinococcus granulosus cyclin dependent kinase 19 0.013 0.04 0.0399
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.005 0.0123 0.0318
Schistosoma mansoni opsin-like receptor 0.0102 0.0305 0.0873
Entamoeba histolytica hypothetical protein 0.0074 0.0207 0.0882
Onchocerca volvulus 0.0102 0.0305 0.2963
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.005 0.0123 0.0351
Schistosoma mansoni fkbp-rapamycin associated protein 0.0173 0.0546 0.1565
Brugia malayi intermediate filament protein 0.0026 0.0042 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0052
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.005 0.0123 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0036 0.0076 0.0325
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.0305 0.0304
Schistosoma mansoni neuropeptide receptor 0.0102 0.0305 0.0873
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.0305 0.0304
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.2665 0.2664
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0076 0.0075
Brugia malayi putative neuropeptide receptor 0.0102 0.0305 0.1306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0207 0.0882
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0151 0.0472 0.2023
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0074 0.0208 0.0673
Schistosoma mansoni adenoreceptor 0.0102 0.0305 0.0873
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Onchocerca volvulus 0.005 0.0123 0.1193
Echinococcus granulosus high voltage activated calcium channel beta 0.0084 0.0243 0.0242
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0074 0.0207 0.0586
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0692 0.233 1
Leishmania major cysteine peptidase A (CPA) 0.002 0.0022 0.0043
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0187 0.0594 0.16
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0299 0.098 0.8545
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0074 0.0207 0.4367
Echinococcus granulosus tachykinin peptides receptor 99D 0.0102 0.0305 0.0304
Onchocerca volvulus 0.002 0.0022 0.0209
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0246
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0017 0.0069
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0102 0.0305 0.0304
Giardia lamblia Casein kinase II beta chain 0.0036 0.0075 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0605 0.2592
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0132 0.056
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.0099
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0031 0.0087
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0324 0.1067 0.4577
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0024 0.0098
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0116 0.0351 0.1138
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0347 0.1144 0.3098
Schistosoma mansoni survival motor neuron protein 0.0094 0.0274 0.0785
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0075 0.0318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0057 0.015 0.0637
Leishmania major protein kinase, putative 0.0025 0.0039 0.0089
Onchocerca volvulus 0.0102 0.0305 0.2963
Loa Loa (eye worm) hypothetical protein 0.0459 0.1529 0.4964
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0157 0.044
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0316 1
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0316 0.1353
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0017 0.0055
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0151 0.0472 1
Onchocerca volvulus 0.0026 0.0042 0.0404
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0036 0.0076 0.0217
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Onchocerca volvulus 0.0102 0.0305 0.2963
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0102 0.0305 0.0988
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0026 0.0043 0.0181
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0051 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0028 0.0078
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0316 0.1353
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0496 0.1658 0.7118
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0151 0.0472 0.4037
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0051 0.0213
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.0001
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0269 0.0877 0.3763
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0022 0.009
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0074 0.0207 0.419
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0217 0.1775
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0157 0.0156
Echinococcus granulosus voltage dependent calcium channel 0.0036 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Brugia malayi G-protein coupled receptor 0.0102 0.0305 0.1306
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0022 0.0068
Trichomonas vaginalis alpha-amylase, putative 0.0129 0.0396 0.1696
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0157 0.0668
Onchocerca volvulus 0.0102 0.0305 0.2963
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.2924 1 1
Trypanosoma cruzi casein kinase II, putative 0.0133 0.0411 0.1183
Brugia malayi Dopamine receptor protein 1 0.0102 0.0305 0.1306
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0018 0.0524
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0075 0.0202
Brugia malayi GnHR receptor homolog 0.0102 0.0305 0.1306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Echinococcus multilocularis G-protein coupled receptor, putative 0.0102 0.0305 0.0304
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0618 0.2076 0.891
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0157 0.0668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0022 0.009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0305 0.0304
Echinococcus multilocularis lamin dm0 0.0026 0.0042 0.0041
Brugia malayi 6-phosphofructokinase 0.0106 0.0316 0.1355
Echinococcus granulosus somatostatin receptor 0.0102 0.0305 0.0304
Entamoeba histolytica hypothetical protein 0.0187 0.0595 0.255
Echinococcus multilocularis Zinc finger, PHD finger 0.0151 0.0472 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0067
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0116 0.0351 0.035
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0594 0.2545
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0017 0.0046
Onchocerca volvulus 0.002 0.0022 0.0209
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0022 0.0158
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1028 0.3484 0.3483
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0274 0.1174
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0008 0.0008
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0073 0.2283
Echinococcus multilocularis cysteine protease 0.002 0.0022 0.0021
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0192 0.0612 0.4479
Loa Loa (eye worm) hypothetical protein 0.0331 0.109 0.3538
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0022 0.0092
Brugia malayi neuropeptide F receptor 0.0102 0.0305 0.1306
Leishmania major cathepsin L-like protease 0.002 0.0022 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0028 0.0078
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.000000012475
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Trichomonas vaginalis PIKK family atypical protein kinase 0.023 0.0743 0.3186
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0494 0.1651 0.165
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Schistosoma mansoni alpha-amylase 0.0014 0.0001 0.0001
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0102 0.0305 0.0873
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0411 0.1759
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0017 0.0069
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0151 0.0472 0.4426
Schistosoma mansoni lamin 0.0026 0.0042 0.0119
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0017 0.0016
Leishmania major phosphatidylinositol 4-kinase, putative 0.0074 0.0207 0.0545
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0075 0.0705
Loa Loa (eye worm) hypothetical protein 0.0113 0.0341 0.1106
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0046
Loa Loa (eye worm) alpha amylase 0.0014 0.0001 0.0002
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0102 0.0305 0.0873
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0074 0.0207 0.0882
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Brugia malayi ORL1-like opioid receptor 0.0102 0.0305 0.1306
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.013 0.04 0.1298
Brugia malayi sulfakinin receptor protein 0.0102 0.0305 0.1306
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0326 0.1074 0.3488
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0102 0.0305 0.0988
Echinococcus granulosus 7tm_1 domain containing protein 0.0102 0.0305 0.0304
Echinococcus multilocularis cyclin dependent kinase 19 0.013 0.04 0.0399
Brugia malayi Cathepsin L-like precursor 0.002 0.0022 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0052 0.0146
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0123 0.0524
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0118 0.0337
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0022 0.0061
Plasmodium falciparum glycogen synthase kinase 3 0.005 0.0123 0.2367
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0008 0.0022
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0073 0.0311
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0017 0.0069
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0022 0.0046
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0008 0.0008
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.005 0.0123 0.0342
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0017 0.0016
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0075 0.0318
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0017 0.0046
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0084 0.0243 0.0695
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0151 0.0472 0.1354
Brugia malayi hypothetical protein 0.0102 0.0305 0.1306
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0305 0.0304
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.0305 0.0304
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0016 0.0008 0.0008
Echinococcus granulosus serotonin receptor 0.0102 0.0305 0.0304
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0088 0.0255 0.0729
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0028 0.0089
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0026 0.0043 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0305 0.0873
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0008 0.0008
Giardia lamblia Phosphatidylinositol 4-kinase 0.0074 0.0207 0.1243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0173 0.0546 0.2339
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0157 0.0668
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0151 0.0472 0.1354
Loa Loa (eye worm) hypothetical protein 0.0102 0.0305 0.0988
Echinococcus granulosus sex peptide receptor 0.0102 0.0305 0.0304
Onchocerca volvulus Neuropeptide F receptor homolog 0.0102 0.0305 0.2963
Schistosoma mansoni voltage-gated potassium channel 0.0081 0.023 0.066
Schistosoma mansoni amine GPCR 0.0102 0.0305 0.0873

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = nM Tested in vitro for amylase release from rat pancreatic acini ChEMBL. 7692048
EC50 (functional) = 0 nM Tested in vitro for amylase release from rat pancreatic acini ChEMBL. 7692048
IC50 (functional) = 1 nM Tested in vitro for inhibition of amylase release from rat pancreatic acini ChEMBL. 7692048
IC50 (functional) = 1 nM Tested in vitro for inhibition of amylase release from rat pancreatic acini ChEMBL. 7692048
IC50 (binding) = 18 nM Inhibition of [125I]-BH-CCK- binding to peripheral cholecystokinin type B receptor from rat pancreatic acini ChEMBL. 7692048
IC50 (binding) = 18 nM Inhibition of [125I]-BH-CCK- binding to peripheral cholecystokinin type B receptor from rat pancreatic acini ChEMBL. 7692048
IC50 (binding) = 1750 nM Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from guinea pig brain membranes ChEMBL. 7692048
IC50 (binding) = 1750 nM Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from guinea pig brain membranes ChEMBL. 7692048
IC50 (binding) = 1800 nM Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from jurkat Tcells ChEMBL. 7692048
IC50 (binding) = 1800 nM Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from jurkat Tcells ChEMBL. 7692048

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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