Detailed information for compound 402544

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1274.39 | Formula: C61H79N17O14
  • H donors: 17 H acceptors: 16 LogP: -2.26 Rotable bonds: 42
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@@H]1C(=O)O)CCCN=C(N)N)CC(C)C)Cc1nc2c([nH]1)cccc2)Cc1ccc(cc1)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)N)Cc1c[nH]cn1
  • InChi: 1S/C61H79N17O14/c1-32(2)23-43(53(84)71-42(13-7-21-66-61(63)64)59(90)78-22-8-14-49(78)60(91)92)73-57(88)47(27-50-69-40-11-5-6-12-41(40)70-50)76-54(85)44(24-33-15-17-36(80)18-16-33)74-58(89)48(30-79)77-55(86)45(25-34-28-67-39-10-4-3-9-37(34)39)75-56(87)46(26-35-29-65-31-68-35)72-52(83)38(62)19-20-51(81)82/h3-6,9-12,15-18,28-29,31-32,38,42-49,67,79-80H,7-8,13-14,19-27,30,62H2,1-2H3,(H,65,68)(H,69,70)(H,71,84)(H,72,83)(H,73,88)(H,74,89)(H,75,87)(H,76,85)(H,77,86)(H,81,82)(H,91,92)(H4,63,64,66)/t38-,42-,43-,44-,45-,46-,47-,48-,49+/m0/s1
  • InChiKey: NCENHXKRPHBKAG-OWAHGJAZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0175 0.046
Brugia malayi PXA domain containing protein 0.002 0.0023 0.0037
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0025 0.0041 0.0167
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0025 0.0041 0.0066
Echinococcus granulosus casein kinase ii subunit alpha 0.0144 0.049 0.049
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.0041 0.0167
Brugia malayi hypothetical protein 0.0019 0.0018 0.0029
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0031 0.0062 0.0099
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0018 0.0018
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0371 0.1348 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0099 0.0218
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0112 0.037 0.1036
Echinococcus multilocularis Zinc finger, PHD finger 0.0165 0.0569 0.0569
Schistosoma mansoni protein kinase 0.0056 0.0158 0.0347
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.028 0.0613
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0115 0.0379 0.0379
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0165 0.0569 0.1872
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0158 0.0347
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0216 0.0762 0.4499
Schistosoma mansoni single-minded 0.0048 0.0128 0.0281
Onchocerca volvulus Serine\/threonine kinase homolog 0.0198 0.0695 0.2259
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0331
Schistosoma mansoni protein kinase 0.0056 0.0158 0.0347
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0056 0.013
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0797 0.2958 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0198 0.0695 0.1996
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0658 0.2432 0.8209
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.003 0.0066
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0037 0.0055
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0165 0.0569 0.0569
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0353 0.0773
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0174 0.0604 0.1727
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0081 0.0081
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0599 0.2209 0.3544
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0165 0.0569 0.0912
Brugia malayi Angiotensin-converting enzyme family protein 0.0599 0.2209 0.3544
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0165 0.0569 0.0557
Entamoeba histolytica protein kinase, putative 0.0059 0.0168 0.0511
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0168 0.0511
Echinococcus granulosus voltage dependent calcium channel 0.0032 0.0066 0.0066
Onchocerca volvulus 0.0026 0.0046 0.0089
Leishmania major hypothetical protein, conserved 0.0993 0.3697 1
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0079
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0018 0.0018
Brugia malayi hypothetical protein 0.0019 0.0018 0.0029
Onchocerca volvulus 0.0036 0.0081 0.0205
Mycobacterium ulcerans zinc metalloprotease 0.0091 0.0291 0.2047
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0353 1
Trichomonas vaginalis hypothetical protein 0.0371 0.1348 0.4525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0083 0.0191
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0174 0.0604 0.0604
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0025 0.0041 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3812
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0371 0.1348 1
Onchocerca volvulus 0.0059 0.0168 0.0497
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0185 0.0644 0.213
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0079
Brugia malayi Peptidase family M13 containing protein 0.0091 0.0291 0.0467
Brugia malayi Cam kinase protein 1 0.0056 0.0158 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0174 0.0604 0.1993
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0056 0.013
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0025 0.0041 0.0061
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0797 0.2958 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0018 0.0018
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0018 0.0029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0091 0.0291 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0077 0.0235 0.1603
Entamoeba histolytica hypothetical protein 0.0077 0.0235 0.0739
Echinococcus multilocularis lamin 0.0026 0.0046 0.0046
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0037 0.0055
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0228 0.0806 0.2323
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.1267 0.4249
Echinococcus multilocularis expressed conserved protein 0.016 0.0549 0.0549
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0299 0.1077 0.2878
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0031 0.0062 0.0099
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0144 0.049 0.3544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0299 0.1077 0.3602
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0168 0.0511
Echinococcus granulosus single minded 2 0.0036 0.0081 0.0081
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0083 0.0222
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0056 0.0158 0.1049
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0025 0.0041 0.0023
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Loa Loa (eye worm) hypothetical protein 0.0191 0.0668 0.1071
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0079
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0032 0.0066 0.0106
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0091 0.029 0.0801
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0047 0.0047
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0115 0.0379 0.0607
Loa Loa (eye worm) peptidase family M13 containing protein 0.0067 0.0201 0.0322
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0304 0.1095 0.3663
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0065
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0059 0.0168 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0077 0.0235 0.0515
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0031 0.0062 0.0099
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0056 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0235 0.1627
Plasmodium vivax hypothetical protein 0.0077 0.0235 0.1627
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0022 0.003 0.0066
Toxoplasma gondii protein kinase, putative 0.263 0.9884 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0056 0.013
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0025 0.0025
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0175 0.046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.003
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0222 0.0222
Onchocerca volvulus 0.0025 0.0041 0.0072
Loa Loa (eye worm) phosphatidylinositol 3 0.0377 0.137 0.2197
Plasmodium falciparum calcium-dependent protein kinase 1 0.0056 0.0158 0.0145
Schistosoma mansoni MAGUK homolog 0.0019 0.002 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0478 0.1048
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0353 0.0566
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0062 0.0136
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0584 0.2151 0.7254
Trichomonas vaginalis conserved hypothetical protein 0.0191 0.0668 0.2211
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0377 0.137 0.3673
Brugia malayi phosphofructokinase 0.0108 0.0353 0.0567
Echinococcus multilocularis calcium dependent protein kinase 0.0045 0.0114 0.0114
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0019 0.002 0.002
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0056 0.0158 0.1033
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0018 0.0018
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0102 0.0285
Brugia malayi 6-phosphofructokinase 0.0108 0.0353 0.0567
Echinococcus multilocularis geminin 0.0166 0.0575 0.0575
Trypanosoma brucei target of rapamycin kinase 3, putative 0.035 0.1268 0.9245
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0467 0.1709 0.2742
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0018 0.0039
Echinococcus granulosus expressed protein 0.037 0.1344 0.1344
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0198 0.0695 0.1114
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Giardia lamblia Hypothetical protein 0.0077 0.0235 0.1142
Brugia malayi serine/threonine-protein kinase plk-2 0.0198 0.0695 0.1115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.1037 0.3466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.0809 0.2689
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0378 0.1376 0.4618
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0018 0.0039
Brugia malayi Protein kinase domain containing protein 0.0141 0.0478 0.0767
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0057 0.0125
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0059 0.0168 0.0269
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0353 0.0566
Brugia malayi Pre-SET motif family protein 0.0204 0.0719 0.1153
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0077 0.0235 0.0235
Brugia malayi hypothetical protein 0.0036 0.0081 0.013
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0803 0.2982 0.2982
Echinococcus multilocularis lamin dm0 0.0026 0.0046 0.0046
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Brugia malayi 6-phosphofructokinase 0.0108 0.0353 0.0567
Schistosoma mansoni hypothetical protein 0.0166 0.0575 0.126
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0353 0.114
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0025 0.0041 0.0066
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0083 0.0213
Leishmania major phosphatidylinositol 3-kinase, putative 0.0165 0.0569 0.1495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.0809 0.2689
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.1267 0.4249
Toxoplasma gondii target of rapamycin (TOR), putative 0.0343 0.1241 0.1239
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Loa Loa (eye worm) phosphatidylinositol 3 0.0299 0.1077 0.1728
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.137 0.4597
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0719 0.1152
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0377 0.137 0.3986
Brugia malayi Pre-SET motif family protein 0.0029 0.0057 0.0091
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0131 0.0288
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0377 0.137 1
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0079
Onchocerca volvulus 0.0026 0.0046 0.0089
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0797 0.2958 0.8674
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0066 0.0066
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.012 0.0263
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0032 0.0066 0.0066
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0165 0.0569 0.1872
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0056 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.137 0.4597
Echinococcus multilocularis 0.0077 0.0235 0.0235
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Leishmania major phosphatidylinositol 3-kinase, putative 0.0289 0.1037 0.2768
Loa Loa (eye worm) hypothetical protein 0.0279 0.1002 0.1607
Plasmodium vivax glycogen synthase kinase 3, putative 0.0059 0.0168 0.1123
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0047 0.0075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0025 0.0041 0.0066
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0079
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0025 0.0041 0.0066
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.006 0.0175 0.0175
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0353 0.0353
Plasmodium vivax SET domain protein, putative 0.0029 0.0057 0.0286
Entamoeba histolytica hypothetical protein 0.0036 0.0081 0.0214
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.051 0.0817
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0811 0.301 0.4828
Entamoeba histolytica protein kinase, putative 0.0056 0.0158 0.0477
Entamoeba histolytica hypothetical protein 0.0189 0.0659 0.218
Entamoeba histolytica hypothetical protein 0.0077 0.0235 0.0739
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0168 0.0511
Onchocerca volvulus 0.0025 0.0041 0.0072
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0041 0.0169
Loa Loa (eye worm) hypothetical protein 0.0091 0.0291 0.0466
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0091 0.0291 0.0467
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0811 0.301 0.301
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0825 0.2746
Schistosoma mansoni hypothetical protein 0.0036 0.0081 0.0177
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0189 0.0659 0.1889
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0081 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Echinococcus granulosus bloom syndrome protein 0.0021 0.0025 0.0025
Brugia malayi PAS domain containing protein 0.0048 0.0128 0.0206
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0077 0.0235 0.0515
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0811 0.301 0.4828
Giardia lamblia Kinase, CMGC CK2 0.0144 0.049 0.2767
Echinococcus multilocularis musashi 0.0026 0.0046 0.0046
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0059 0.0168 0.0441
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0349 0.1265 0.4241
Loa Loa (eye worm) phosphatidylinositol 3 0.0077 0.0235 0.0377
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0105
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0077 0.0235 0.0222
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0165 0.0569 0.0912
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0019 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0189 0.0659 0.218
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0299 0.1077 0.7835
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0077 0.0235 0.0219
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0025 0.0041 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.1037 0.3466
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0338 0.1088
Loa Loa (eye worm) phosphatidylinositol 3 0.1083 0.4038 0.6479
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0057 0.0039
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0032 0.0066 0.0066
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.028 0.0613
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0028
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0046 0.012 0.0263
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0066 0.0066
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0353 0.114
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0339 0.1225 0.356
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.003 0.0066
Giardia lamblia GTOR 0.0377 0.137 0.8375
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0174 0.0604 0.0604
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0059 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0166 0.0575 0.126
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0036 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.1267 0.4249
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0165 0.0569 0.1245
Echinococcus granulosus beta-adrenergic receptor kinase 0.0031 0.0062 0.0062
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Loa Loa (eye worm) hypothetical protein 0.0026 0.0046 0.0074
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0353 0.2513
Plasmodium vivax calcium-dependent protein kinase, putative 0.0056 0.0158 0.1049
Leishmania major phosphatidylinositol 4-kinase, putative 0.0077 0.0235 0.0589
Entamoeba histolytica hypothetical protein 0.0036 0.0081 0.0214
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0056 0.013
Loa Loa (eye worm) hypothetical protein 0.0067 0.0201 0.0322
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0018 0.0028
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0027 0.0032
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0018 0.0029
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0167
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0056 0.0158 0.0141
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0165 0.0569 0.1872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3812
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0019 0.0002
Mycobacterium leprae probable zinc metalloprotease 0.0091 0.0291 0.2045
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0056 0.0158 0.1049
Onchocerca volvulus 0.0095 0.0306 0.0957
Leishmania major casein kinase II, putative 0.0144 0.049 0.1282
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Toxoplasma gondii FATC domain-containing protein 0.0189 0.0659 0.0649
Loa Loa (eye worm) phosphatidylinositol 3 0.0077 0.0235 0.0377
Loa Loa (eye worm) oxidoreductase 0.0025 0.0041 0.0065
Schistosoma mansoni hypothetical protein 0.0077 0.0235 0.0515
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Onchocerca volvulus 0.0099 0.0322 0.1012
Toxoplasma gondii CMGC kinase, CK2 family 0.0144 0.049 0.0478
Loa Loa (eye worm) calcium channel 0.0032 0.0066 0.0105
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Plasmodium falciparum protein kinase 7 0.263 0.9884 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0353 0.2475
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0047 0.0099
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0353 0.2513
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0057 0.0057
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0189 0.0659 0.4739
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0377 0.137 0.3
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0045 0.0117 0.0187
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.003 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0235 0.0739
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0019 0.0029
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0056 0.0114
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0831 0.1333
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0175 0.0533
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0175 0.1154
Schistosoma mansoni intermediate filament proteins 0.0026 0.0046 0.0101
Trypanosoma brucei protein kinase, putative 0.0059 0.0168 0.1107
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0128 0.0281
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0339 0.1225 0.2684
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0047 0.0075
Brugia malayi hypothetical protein 0.01 0.0323 0.0518
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0165 0.0569 0.0569
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0083 0.0478
Loa Loa (eye worm) hypothetical protein 0.0099 0.0322 0.0516
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0371 0.1348 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0077 0.0235 0.0377
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0025 0.0041 0.0026
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0032 0.0066 0.0145
Loa Loa (eye worm) hypothetical protein 0.0563 0.2073 0.3325
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0077 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0028
Echinococcus granulosus lamin dm0 0.0026 0.0046 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.0077 0.0235 0.0377
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0041 0.0167
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0081 0.0177
Giardia lamblia Phosphatidylinositol 4-kinase 0.0077 0.0235 0.1142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0022 0.003 0.0066
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0175 0.0533
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0056 0.0038
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0014
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0091 0.0291 0.2045
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0168 0.0511
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0056 0.0041
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Brugia malayi PXA domain containing protein 0.002 0.0023 0.0037
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1222 0.4565 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.0809 0.2689
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0377 0.137 1
Brugia malayi intermediate filament protein 0.0026 0.0046 0.0074
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0046 0.0074
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0198 0.0695 0.0695
Leishmania major protein kinase, putative 0.0024 0.0037 0.0051
Schistosoma mansoni fkbp-rapamycin associated protein 0.0174 0.0604 0.1323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Loa Loa (eye worm) hypothetical protein 0.0067 0.0201 0.0322
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0037 0.0055
Entamoeba histolytica serine/threonine protein kinase, putative 0.0198 0.0695 0.2303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0315 0.1011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3814
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0023 0.0037
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0167
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0083 0.0176
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0165 0.0569 0.1872
Brugia malayi Serotonin receptor 0.0462 0.1692 0.2715
Echinococcus granulosus tumor protein p63 0.0335 0.1211 0.1211
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0018 0.0029
Loa Loa (eye worm) retinol dehydrogenase 12 0.0025 0.0041 0.0065
Brugia malayi hypothetical protein 0.0467 0.1709 0.2742
Loa Loa (eye worm) hypothetical protein 0.0665 0.246 0.3946
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0147 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.1037 0.3466
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0165 0.0569 0.0569
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0353 0.0353
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0059 0.0168 0.0269
Leishmania major pteridine reductase 1 0.0025 0.0041 0.0061
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0083 0.0484
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0018 0.0018
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0339 0.1225 0.1225
Schistosoma mansoni lamin 0.0026 0.0046 0.0101
Brugia malayi Protein kinase domain containing protein 0.0026 0.0044 0.007
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0175 0.0533
Plasmodium falciparum calcium-dependent protein kinase 4 0.0056 0.0158 0.0145
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0019 0.002 0.002
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0025 0.0041 0.0169
Trypanosoma cruzi casein kinase II, putative 0.0144 0.049 0.1391
Loa Loa (eye worm) hypothetical protein 0.0174 0.0604 0.0969
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0025 0.0041 0.0167
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0047 0.0125 0.02
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0025 0.0041 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0062 0.0136
Loa Loa (eye worm) phosphatidylinositol 3 0.0077 0.0235 0.0377
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0377 0.137 0.4597
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0025 0.0041 0.0167
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0025 0.0025
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.1267 0.4249
Loa Loa (eye worm) gastrulation defective protein 1 0.0129 0.0434 0.0696
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0032 0.0066 0.0145
Loa Loa (eye worm) hypothetical protein 0.0029 0.0057 0.0091
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0353 0.0566
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0077 0.0235 0.0639
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0018 0.0039
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0018 0.0018
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0025 0.0041 0.0079
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0077 0.0235 0.0219
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Trypanosoma cruzi hypothetical protein, conserved 0.0916 0.3408 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3814
Echinococcus multilocularis protein kinase shaggy 0.0059 0.0168 0.0168
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0025 0.0041 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3814
Echinococcus granulosus intermediate filament protein 0.0026 0.0046 0.0046
Plasmodium vivax unspecified product 0.0144 0.049 0.3544
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0018 0.0039
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0169 0.0586 0.0586
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0322 0.0517
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0083 0.0183
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0077 0.0235 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0147 0.0437
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0083 0.0068
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0081 0.013
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0658 0.2432 0.8209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1241 0.4161
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0053 0.0053
Loa Loa (eye worm) peptidase family M13 containing protein 0.0067 0.0201 0.0322
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0018 0.0018
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0077 0.0235 0.1603
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0331
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0083 0.0222
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0165 0.0569 0.1495
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0147 0.0437
Echinococcus granulosus calcium dependent protein kinase 0.0045 0.0114 0.0114
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Toxoplasma gondii ck2 beta subunit 0.0036 0.0083 0.0065
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0077 0.0235 0.0222
Brugia malayi Casein kinase II, alpha chain 0.0144 0.049 0.0786
Onchocerca volvulus 0.0077 0.0235 0.0721
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0037 0.0055
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0077 0.0235 0.1627
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0041 0.0167
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0056 0.0158 0.0253
Echinococcus granulosus geminin 0.0166 0.0575 0.0575
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0025 0.0041
Echinococcus multilocularis serine protein kinase ATM 0.0189 0.0659 0.0659
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0025 0.0041 0.0041
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0444 0.1625 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0018 0.0039
Leishmania major phosphatidylinositol kinase related protein, putative 0.0091 0.029 0.0738
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0174 0.0604 0.0969
Echinococcus granulosus survival motor neuron protein 1 0.0467 0.1709 0.1709
Brugia malayi hypothetical protein 0.0162 0.0557 0.0894
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0086 0.0271 0.0593
Schistosoma mansoni voltage-gated cation channel 0.0032 0.0066 0.0145
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0377 0.137 0.137
Trypanosoma cruzi target of rapamycin kinase 3 0.035 0.1268 0.3685
Loa Loa (eye worm) RecQ helicase 0.0021 0.0025 0.004
Brugia malayi SH2 domain containing protein 0.0665 0.246 0.3946
Loa Loa (eye worm) zinc metallopeptidase 4 0.0022 0.003 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.1165 0.3902
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0062 0.0136
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0331
Giardia lamblia Kinase, CMGC GSK 0.0059 0.0168 0.0715
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0353 0.114
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0056 0.0158 0.0141
Trypanosoma brucei Casein kinase II 0.0144 0.049 0.3489
Loa Loa (eye worm) hypothetical protein 0.01 0.0323 0.0517
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0056 0.0041
Leishmania major phosphatidylinositol kinase, putative 0.0077 0.0235 0.0589
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0057 0.0057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0141 0.0478 0.0767
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0056 0.028
Trypanosoma cruzi polo-like protein kinase, putative 0.0198 0.0695 0.1996
Schistosoma mansoni neprilysin 0.0024 0.0036 0.0079
Schistosoma mansoni protein kinase 0.0056 0.0158 0.0347
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0056 0.013
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0018 0.0029
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0066 0.0066
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0018 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0077 0.0235 0.0377
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0175 0.1154
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0371 0.1348 1
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.0071
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0056 0.0038
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.006 0.0175 0.0382
Schistosoma mansoni hypothetical protein 0.0115 0.0379 0.083
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0289 0.1037 0.7538
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0059 0.0168 0.0407
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1222 0.4565 0.4565
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0057 0.0125
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0306 0.0491
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0083 0.0222
Schistosoma mansoni protein kinase 0.0144 0.049 0.1074
Trypanosoma brucei polo-like protein kinase 0.0198 0.0695 0.5006
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0165 0.0569 0.056
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0056 0.013
Giardia lamblia Kinase, CMGC GSK 0.0059 0.0168 0.0715
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0056 0.0158 0.0141
Brugia malayi peptidase family M13 containing protein 0.0022 0.003 0.0048
Loa Loa (eye worm) phosphatidylinositol kinase 0.0077 0.0235 0.0377
Giardia lamblia Kinase, PLK 0.0198 0.0695 0.4074
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0165 0.0569 0.1622
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0046 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.137 0.4597
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0083 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0353 0.114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0262 0.0937 0.3125
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0189 0.0659 0.1443
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0059 0.0168 0.0369
Brugia malayi Protein kinase domain containing protein 0.1664 0.6233 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0218 0.0771 0.5565
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0102 0.0245
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0797 0.2958 1
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0018 0.0018
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0304 0.1095 0.7968
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0115 0.0379 0.0379
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0056 0.0158 0.0254
Schistosoma mansoni lamin 0.0026 0.0046 0.0101
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0077 0.0235 0.0639
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0018 0.0018
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0025 0.0041 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0057 0.0125
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0353 0.0909
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0077 0.0235 0.0235
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0165 0.0569 0.0557
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0083 0.0065
Plasmodium falciparum glycogen synthase kinase 3 0.0059 0.0168 0.0155
Loa Loa (eye worm) hypothetical protein 0.0091 0.0291 0.0466
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0066 0.0066
Echinococcus multilocularis beta adrenergic receptor kinase 0.0031 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0036 0.0081 0.0214
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0304 0.1095 0.1757
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0177 0.0615 0.0987
Entamoeba histolytica protein kinase rad3, putative 0.0174 0.0604 0.1993
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0797 0.2958 0.8674
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0057 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.049 0.1606
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0379 0.1228
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0083 0.0484
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0353 0.2515
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0018 0.0018
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0198 0.0695 0.1839
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0018 0.0039
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0041 0.0169
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0025 0.0041 0.0061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0565 0.2081 0.3339
Loa Loa (eye worm) hypothetical protein 0.0049 0.0131 0.021
Brugia malayi Cytochrome P450 family protein 0.0029 0.0057 0.0092
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0811 0.301 1
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0083 0.0083
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0077 0.0235 0.1627
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0175 0.046
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0304 0.1095 0.3663
Echinococcus granulosus lamin 0.0026 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0095 0.0306 0.067
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0077 0.0235 0.0235
Echinococcus granulosus tyrosine protein kinase Lyn 0.0021 0.0027 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Echinococcus granulosus protein kinase shaggy 0.0059 0.0168 0.0168
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.2661 1 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0165 0.0569 0.1245
Echinococcus granulosus endothelin converting enzyme 1 0.0091 0.0291 0.0291
Leishmania major oxidoreductase-like protein 0.0025 0.0041 0.0061
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0144 0.049 0.0786
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.028 0.028
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Schistosoma mansoni hypothetical protein 0.0051 0.0138 0.0303
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0081 0.0468
Echinococcus multilocularis expressed protein 0.037 0.1344 0.1344
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0047 0.0103
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.0235 0.1627
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0339 0.1225 0.356
Plasmodium falciparum calcium-dependent protein kinase 3 0.0056 0.0158 0.0145
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0018 0.0039
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.0019 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0056 0.0158 0.0158
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0018 0.0028
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0025 0.0041 0.0169
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0831 0.1333
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0377 0.137 0.3986
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0584 0.2151 0.7254
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0025 0.0041 0.0061
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0425 0.1553 0.2491
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0235 0.0739
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0169 0.0586 0.0586
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0066 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0353 0.114
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0353 0.0773
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0721 0.2669 0.9017
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0041 0.0169
Brugia malayi Csnk2b protein 0.0036 0.0083 0.0134
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0077
Brugia malayi FAT domain containing protein 0.0115 0.0379 0.0608
Loa Loa (eye worm) hypothetical protein 0.0056 0.0158 0.0253
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0018 0.0018
Schistosoma mansoni neprilysin-2 (M13 family) 0.0046 0.012 0.0263
Brugia malayi Protein kinase domain containing protein 0.0811 0.301 0.4829
Schistosoma mansoni hypothetical protein 0.016 0.0549 0.1203
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0077 0.0235 0.0639
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0235 0.1627
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0041 0.0169
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.0091 0.0291 0.0466
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0331
Entamoeba histolytica protein kinase, putative 0.0057 0.0162 0.0489
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0102 0.0285
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0018 0.0029
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1222 0.4565 0.4565
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0056 0.0158 0.0253
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0191 0.0668 0.0658
Schistosoma mansoni kinase 0.0106 0.0347 0.0761
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Entamoeba histolytica hypothetical protein 0.0036 0.0081 0.0214
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0077 0.0235 0.0639
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0077 0.0235 0.0739
Toxoplasma gondii peptidase family M13 protein 0.0091 0.0291 0.0276
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0169
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0046 0.012 0.0263
Leishmania major protein kinase, putative 0.0024 0.0037 0.0051
Echinococcus multilocularis high voltage activated calcium channel beta 0.0086 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0162 0.0557 0.0893
Toxoplasma gondii hypothetical protein 0.0053 0.0147 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0075
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0079
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0018 0.0018
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0083 0.0083
Brugia malayi intracellular kinase 0.0059 0.0168 0.027
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Onchocerca volvulus 0.0099 0.0322 0.1012
Echinococcus granulosus expressed conserved protein 0.016 0.0549 0.0549
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0047 0.0099
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0018 0.0039
Entamoeba histolytica hypothetical protein 0.0077 0.0235 0.0739
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0047 0.0099
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0165 0.0569 0.4134
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0222 0.0222
Leishmania major hypothetical protein, unknown function 0.0077 0.0235 0.0589
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0056 0.013
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.006 0.0175 0.0175
Mycobacterium ulcerans oxidoreductase 0.0025 0.0041 0.0169
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0158 0.0477
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0339 0.1225 0.1966
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0811 0.301 0.4829
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0377 0.137 0.137
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0057 0.0091
Onchocerca volvulus 0.0233 0.0826 0.2697
Trichomonas vaginalis PIKK family atypical protein kinase 0.0235 0.0834 0.2776
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0059 0.0168 0.0168
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0025 0.0041 0.0167
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0056 0.0158 0.1049
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0025 0.0041 0.0166
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0018 0.0018
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0377 0.137 0.4597
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0019 0.0002
Loa Loa (eye worm) hypothetical protein 0.0112 0.037 0.0593
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0077 0.0235 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0315 0.1011
Trypanosoma brucei oxidoreductase-like protein 0.0025 0.0041 0.0166
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0077 0.0235 0.0739
Loa Loa (eye worm) hypothetical protein 0.0067 0.0201 0.0322
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0025 0.0041 0.009
Plasmodium falciparum enoyl-acyl carrier reductase 0.0371 0.1348 0.1351
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0353 0.114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.0337 0.1086
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0371 0.1348 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.1165 0.3902
Echinococcus multilocularis cyclin dependent kinase 19 0.0141 0.0478 0.0478
Onchocerca volvulus 0.0045 0.0117 0.0326
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0056 0.028
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0304 0.1095 0.3663
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0019 0.0029
Brugia malayi hypoxia-induced factor 1 0.0149 0.051 0.0818
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0353 0.114
Plasmodium falciparum calcium-dependent protein kinase 5 0.0056 0.0158 0.0145
Brugia malayi Cytochrome P450 family protein 0.0019 0.0019 0.003
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0165 0.0569 0.1622
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0695 0.1523
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0077 0.0235 0.0377
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0797 0.2958 1
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0025 0.0041 0.0169
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0025 0.0041 0.0169
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0371 0.1348 1
Echinococcus multilocularis survival motor neuron protein 1 0.0467 0.1709 0.1709
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0797 0.2958 0.4747
Echinococcus multilocularis tumor protein p63 0.0335 0.1211 0.1211
Onchocerca volvulus 0.0041 0.0099 0.0267
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Entamoeba histolytica protein kinase, putative 0.0021 0.0027 0.0032
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0304 0.1095 0.3176
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Echinococcus granulosus high voltage activated calcium channel beta 0.0086 0.0271 0.0271
Echinococcus granulosus serine protein kinase ATM 0.0189 0.0659 0.0659
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0025 0.0041 0.0167
Loa Loa (eye worm) phosphatidylinositol 3 0.0228 0.0806 0.1293
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Plasmodium falciparum calcium-dependent protein kinase 2 0.0056 0.0158 0.0145
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0083 0.0133
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.012 0.0263
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0811 0.301 0.301
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0695 0.2303
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0056 0.0114
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0077 0.0235 0.0739
Schistosoma mansoni dihydropteridine reductase 0.0025 0.0041 0.009
Plasmodium falciparum casein kinase 2, alpha subunit 0.0144 0.049 0.0481
Brugia malayi Cytochrome P450 family protein 0.0019 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0331
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0563 0.2073 0.2073
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0018 0.0018
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0339 0.1225 0.1225
Onchocerca volvulus 0.0077 0.0235 0.0721
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0077 0.0235 0.1627
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0083 0.0213
Schistosoma mansoni endothelin-converting enzyme-related 0.0022 0.003 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0252 0.0898 0.2994
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0563 0.2073 0.2073
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0189 0.0659 0.1057
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Giardia lamblia Casein kinase II beta chain 0.0036 0.0083 0.0173
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0083 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0304 0.1095 0.3663
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.1267 0.4249
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0041 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1139 0.3814
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0077 0.0235 0.0515
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0811 0.301 0.6593
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.049 0.1606
Echinococcus multilocularis endothelin converting enzyme 1 0.0091 0.0291 0.0291
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0165 0.0569 0.1872
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0177 0.0615 0.0987
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0056 0.0158 0.0158
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0131 0.044 0.3116
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0025 0.0041 0.0065
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0175 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0185 0.0644 0.213
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0338 0.1088
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0331
Schistosoma mansoni survival motor neuron protein 0.0095 0.0306 0.067
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.0077 0.0235 0.0377
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1664 0.6233 1
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0032 0.0066 0.0066
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0066 0.0066
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0351 0.1274 0.279
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0377 0.137 0.2198
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.035 0.1268 0.3396
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0 0.0001
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0009 0.0019
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0175 0.0533
Echinococcus multilocularis casein kinase ii subunit alpha 0.0144 0.049 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0003
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0083 0.0068
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0377 0.137 0.3673
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0353 0.0987
Trypanosoma brucei pteridine reductase 1 0.0025 0.0041 0.0166
Entamoeba histolytica casein kinase, putative 0.0144 0.049 0.1606
Leishmania major protein kinase, putative 0.0056 0.0158 0.038
Echinococcus granulosus cyclin dependent kinase 19 0.0141 0.0478 0.0478
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0041 0.0167
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0198 0.0695 0.0695
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.1037 0.3466
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0165 0.0569 0.407
Loa Loa (eye worm) hypothetical protein 0.0067 0.0201 0.0322
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.028 0.028
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0081 0.0081
Onchocerca volvulus 0.0049 0.0131 0.0374
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0041 0.0169
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0371 0.1348 0.1348

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1 Antifertility effect of the compound was tested in adult female rats by estrus suppression assay ChEMBL. 6366232

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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