Detailed information for compound 413343

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 386.417 | Formula: C21H23FN2O4
  • H donors: 2 H acceptors: 2 LogP: 3.88 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)NC(=O)N[C@@H]1CC[C@@H](CC1)Oc1ccc(cc1)F
  • InChi: 1S/C21H23FN2O4/c1-27-20(25)14-2-6-16(7-3-14)23-21(26)24-17-8-12-19(13-9-17)28-18-10-4-15(22)5-11-18/h2-7,10-11,17,19H,8-9,12-13H2,1H3,(H2,23,24,26)/t17-,19+
  • InChiKey: LQCBKHAUABSQEX-IZAXUBKRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) Get druggable targets OG5_129061 All targets in OG5_129061
Mycobacterium ulcerans epoxide hydrolase EphA Get druggable targets OG5_129061 All targets in OG5_129061
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0057 0.0017 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.013 0.013
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0051 0.0006 0.0003
Echinococcus multilocularis protein tyrosine kinase 0.0287 0.0438 0.0435
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0182 0.0247 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0044 0.0044
Schistosoma mansoni tyrosine kinase 0.0261 0.0391 0.0391
Schistosoma mansoni protein kinase 0.006 0.0023 0.0023
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0074 0.0048 0.0069
Schistosoma mansoni protein kinase 0.0111 0.0116 0.0116
Echinococcus granulosus roundabout 2 0.015 0.0189 0.0185
Leishmania major phosphatidylinositol kinase, putative 0.0167 0.022 0.0792
Echinococcus multilocularis neuroglian 0.0124 0.014 0.0136
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0023 0.0031
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1069 0.1867 0.2875
Trichomonas vaginalis AGC family protein kinase 0.0097 0.0091 0.0114
Echinococcus granulosus tyrosine protein kinase Fyn 0.0237 0.0346 0.0343
Loa Loa (eye worm) hypothetical protein 0.0099 0.0095 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0665 0.1002
Leishmania major protein kinase A catalytic subunit 0.0097 0.0091 0.0272
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0167 0.022 0.2448
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0027 0.003
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.007 0.0042 0.0065
Echinococcus granulosus neuroglian 0.0124 0.014 0.0136
Onchocerca volvulus 0.0112 0.0119 0.0745
Schistosoma mansoni tyrosine kinase 0.0056 0.0017 0.0017
Schistosoma mansoni tyrosine kinase 0.0218 0.0312 0.0312
Schistosoma mansoni atypical protein kinase C 0.0071 0.0044 0.0044
Echinococcus granulosus tyrosine kinase 0.0084 0.0067 0.0064
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0381 0.061 0.061
Brugia malayi Protein kinase domain containing protein 0.0087 0.0072 0.0111
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0163 0.0226
Brugia malayi Protein kinase domain containing protein 0.0182 0.0247 0.0381
Echinococcus multilocularis serine protein kinase ATM 0.0266 0.0399 0.0396
Trichomonas vaginalis AGC family protein kinase 0.0119 0.0132 0.0178
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0197 0.0274 0.027
Loa Loa (eye worm) hypothetical protein 0.011 0.0115 0.0131
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0104 0.0104 0.0326
Echinococcus multilocularis mitogen activated protein kinase 11 0.0142 0.0173 0.0169
Loa Loa (eye worm) AGC/NDR protein kinase 0.0057 0.0017 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0031 0.0022
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0099 0.0094 0.0091
Echinococcus multilocularis 0.0109 0.0113 0.0109
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0163 0.0212 0.0761
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0163 0.0212 0.0242
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0023 0.0031
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.3596 0.6483 1
Onchocerca volvulus 0.0049 0.0003 0.0022
Trypanosoma brucei casein kinase I, isoform 2 0.0093 0.0083 0.0367
Plasmodium falciparum calcium-dependent protein kinase 2 0.007 0.0042 0.0219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0402 0.0648 0.0976
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0142 0.0173 0.0197
Loa Loa (eye worm) hypothetical protein 0.0231 0.0336 0.0385
Brugia malayi Variant SH3 domain containing protein 0.008 0.0061 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0393 0.0631 0.095
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0128 0.0149 0.0145
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0027 0.0027
Echinococcus multilocularis protein KINase family member (kin 25) 0.0103 0.0102 0.0099
Toxoplasma gondii AGC kinase 0.0097 0.0091 0.0741
Schistosoma mansoni lysosomal protective protein precursor (cathepsin A) (carboxypeptidase 0.0074 0.0049 0.0049
Echinococcus granulosus serine:threonine protein kinase 0.0098 0.0093 0.0089
Loa Loa (eye worm) hypothetical protein 0.0049 0.0003 0.0002
Echinococcus granulosus tyrosine protein kinase Srms 0.0084 0.0067 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0029 0.0029
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0167 0.022 0.0334
Schistosoma mansoni protein kinase 0.0127 0.0145 0.0145
Schistosoma mansoni neuroglian 0.0051 0.0006 0.0006
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0057 0.0017 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0182 0.0182
Brugia malayi Variant SH3 domain containing protein 0.0058 0.002 0.003
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0292 0.0447 0.2046
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0058 0.002 0.002
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0411 0.0665 0.3051
Entamoeba histolytica protein kinase, putative 0.0087 0.0072 0.0109
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1236 0.2173 0.3351
Echinococcus multilocularis mitogen activated protein kinase 14 0.0142 0.0173 0.0169
Entamoeba histolytica hypothetical protein 0.0167 0.022 0.0337
Loa Loa (eye worm) hypothetical protein 0.015 0.0187 0.0214
Echinococcus granulosus casein kinase I alpha 0.0093 0.0083 0.008
Brugia malayi Protein kinase domain containing protein 0.0903 0.1564 0.2412
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0193 0.0266 0.0405
Echinococcus multilocularis death associated protein kinase 1 0.0812 0.1398 0.1395
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0534 0.0889 0.1348
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0058 0.002 0.002
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0051 0.0006 0.0003
Echinococcus granulosus lysosomal protective protein 0.0746 0.1277 0.1274
Brugia malayi intracellular kinase 0.0112 0.0119 0.0183
Echinococcus granulosus contactin 0.0051 0.0006 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0115 0.0124 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.061 0.0917
Onchocerca volvulus 0.0084 0.0067 0.0423
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0108 0.011 0.0107
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0136 0.0163 0.0186
Echinococcus multilocularis basement membrane specific heparan sulfate 0.01 0.0096 0.0093
Echinococcus multilocularis growth factor receptor bound protein 2 0.008 0.0061 0.0057
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0098 0.0093 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0044 0.0044
Echinococcus granulosus cyclin dependent kinase 9 0.0063 0.0029 0.0025
Echinococcus multilocularis protein kinase c epsilon type 0.0071 0.0044 0.0041
Echinococcus multilocularis cyclin dependent kinase 9 0.0063 0.0029 0.0025
Giardia lamblia Kinase, CMGC CLK 0.0136 0.0163 0.0496
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0115 0.0177
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0111 0.0116 0.0132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0178 0.024 0.0236
Trichomonas vaginalis AGC family protein kinase 0.0128 0.0149 0.0203
Trichomonas vaginalis AGC family protein kinase 0.0128 0.0149 0.0203
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1236 0.2173 0.2173
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0097 0.0091 0.0994
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.3596 0.6483 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0167 0.022 0.2156
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0093 0.0117
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0411 0.0665 0.0665
Echinococcus granulosus tyrosine protein kinase Src64B 0.0237 0.0346 0.0343
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0411 0.0665 0.2588
Brugia malayi P38 map kinase family protein 2 0.0142 0.0173 0.0266
Plasmodium falciparum calcium-dependent protein kinase 1 0.007 0.0042 0.0219
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.007 0.0042 0.0048
Brugia malayi Protein kinase domain containing protein 0.0176 0.0236 0.0363
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0006 0.001
Schistosoma mansoni protein kinase 0.0089 0.0076 0.0076
Brugia malayi Tyrosine-protein kinase abl-1 0.0254 0.0378 0.0584
Echinococcus multilocularis myosin iiia 0.0069 0.004 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Loa Loa (eye worm) hypothetical protein 0.0098 0.0093 0.0106
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0097 0.0091 0.0135
Loa Loa (eye worm) variant SH3 domain-containing protein 0.008 0.0061 0.0069
Loa Loa (eye worm) TK/ABL protein kinase 0.0496 0.082 0.0939
Trichomonas vaginalis PIKK family atypical protein kinase 0.0167 0.022 0.0313
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0266 0.0399 0.0611
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0138 0.0167 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Onchocerca volvulus 0.0135 0.016 0.1007
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0237 0.0346 0.0396
Entamoeba histolytica hypothetical protein 0.2893 0.52 0.802
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.007 0.0042 0.0448
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0085 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0042 0.0042
Echinococcus granulosus roundabout 2 0.0051 0.0006 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0284 0.0433 0.0644
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0068 0.0038 0.0035
Echinococcus granulosus fibroblast growth factor receptor 4 0.0137 0.0165 0.0161
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0167 0.022 0.0216
Loa Loa (eye worm) phosphatidylinositol 3 0.1069 0.1867 0.2141
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.0771 0.0771
Schistosoma mansoni tyrosine kinase 0.0237 0.0346 0.0346
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0049 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.013 0.013
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0251 0.0373 0.0369
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0063 0.0029 0.0032
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0058 0.002 0.0016
Echinococcus granulosus serine:threonine protein kinase 3 0.0237 0.0346 0.0343
Brugia malayi Protein kinase domain containing protein 0.0084 0.0067 0.0104
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0098 0.0093 0.0105
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0534 0.0889 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0133 0.0156 0.0153
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0237 0.0346 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0163 0.0163
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0027 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0042 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.061 0.0917
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0167 0.022 0.0337
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0084 0.0067 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0199 0.0278 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Schistosoma mansoni growth factor receptor-bound protein 0.008 0.0061 0.0061
Giardia lamblia GTOR 0.0411 0.0665 0.2052
Brugia malayi serine/threonine-protein kinase 6 0.0128 0.0149 0.0229
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0534 0.0889 0.4082
Echinococcus multilocularis activin receptor type 0.0417 0.0675 0.0672
Brugia malayi hypothetical protein 0.011 0.0115 0.0177
Echinococcus multilocularis activated cdc42 kinase 1 0.0202 0.0284 0.028
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0136 0.0163 0.0246
Onchocerca volvulus 0.0084 0.0067 0.0423
Loa Loa (eye worm) TK protein kinase 0.0199 0.0278 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0276 0.04
Entamoeba histolytica PH domain containing protein kinase, putative 0.0049 0.0003 0.0003
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0411 0.0665 0.0662
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0097 0.0091 0.0135
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0192 0.0265 0.2956
Entamoeba histolytica protein kinase , putative 0.0128 0.0149 0.0227
Brugia malayi hypothetical protein 0.006 0.0023 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.2518 0.4515 0.6956
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.016 0.016
Schistosoma mansoni tyrosine kinase 0.0394 0.0634 0.0634
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0163 0.0212 0.0327
Plasmodium vivax calcium-dependent protein kinase, putative 0.007 0.0042 0.0448
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.2313 0.4141 0.4139
Entamoeba histolytica hypothetical protein 0.0266 0.0399 0.0614
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0061 0.0025 0.0027
Loa Loa (eye worm) IKK protein kinase 0.0919 0.1593 0.1826
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0534 0.0889 0.1367
Brugia malayi SH2 domain containing protein 0.0084 0.0067 0.0104
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0142 0.0173 0.0261
Echinococcus granulosus tar DNA binding protein 0.0062 0.0027 0.0024
Echinococcus granulosus insulin receptor 0.0261 0.0391 0.0388
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0192 0.0265 0.0265
Echinococcus granulosus Immunoglobulin 0.01 0.0096 0.0093
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0135 0.016 0.0157
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Schistosoma mansoni tyrosine kinase 0.0256 0.0382 0.0382
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0052 0.0009 0.0009
Brugia malayi serine/threonine-protein kinase PAK 7 0.0197 0.0275 0.0423
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0167 0.022 0.0216
Giardia lamblia Kinase, NEK 0.0119 0.0132 0.04
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0137 0.0165 0.0161
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0381 0.061 0.0606
Schistosoma mansoni hypothetical protein 0.0166 0.0217 0.0217
Echinococcus granulosus dual specificity 0.0193 0.0266 0.0262
Toxoplasma gondii AGC kinase 0.0097 0.0091 0.0741
Echinococcus multilocularis raf serine:threonine protein kinase 0.0056 0.0016 0.0012
Schistosoma mansoni tyrosine kinase 0.0215 0.0307 0.0307
Trypanosoma brucei serine peptidase, Clan SC, Family S10 0.0746 0.1277 0.5871
Loa Loa (eye worm) hypothetical protein 0.0135 0.016 0.0183
Echinococcus multilocularis cyclin dependent kinase 7 0.0094 0.0085 0.0082
Echinococcus multilocularis dual specificity mitogen activated protein 0.0163 0.0212 0.0209
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0182 0.0247 0.0282
Echinococcus multilocularis family S10 non peptidase ue (S10 family) 0.0672 0.1142 0.1139
Leishmania major protein kinase, putative 0.007 0.0042 0.0077
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0042 0.0039
Leishmania major serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 0.0746 0.1277 0.5055
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Echinococcus multilocularis cyclin dependent kinase 1 0.0061 0.0025 0.0021
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Brugia malayi Protein kinase domain containing protein 0.0071 0.0043 0.0066
Loa Loa (eye worm) hypothetical protein 0.0049 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0191 0.0264 0.0301
Schistosoma mansoni adapter molecule crk 0.008 0.0061 0.0061
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0116 0.0126 0.0123
Trypanosoma brucei serine peptidase, Clan SC, Family S10 0.0746 0.1277 0.5871
Brugia malayi Protein kinase domain containing protein 0.0061 0.0025 0.0038
Echinococcus granulosus geminin 0.0166 0.0217 0.0213
Schistosoma mansoni nephrin 0.0134 0.0158 0.0158
Plasmodium falciparum protein kinase 5 0.0061 0.0025 0.0016
Leishmania major phosphatidylinositol 4-kinase, putative 0.0192 0.0265 0.0973
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0027 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0011 0.0011
Echinococcus granulosus cyclin dependent kinase 5 0.0061 0.0025 0.0021
Echinococcus granulosus protein kinase C gamma type 0.0057 0.0017 0.0014
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0469 0.0771 0.0883
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0176 0.0236 0.0232
Loa Loa (eye worm) hypothetical protein 0.01 0.0097 0.011
Trichomonas vaginalis AGC family protein kinase 0.0128 0.0149 0.0203
Echinococcus multilocularis serine:threonine protein kinase N2 0.0057 0.0017 0.0014
Brugia malayi Protein kinase domain containing protein 0.0136 0.0163 0.0251
Echinococcus multilocularis tyrosine protein kinase shark 0.0084 0.0067 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0043 0.004
Trypanosoma cruzi aurora B kinase, putative 0.0128 0.0149 0.0224
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.3428 0.6177 0.9528
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.0336 0.0333
Schistosoma mansoni tyrosine kinase 0.0137 0.0165 0.0165
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0049 0.0003 0.0000005084
Entamoeba histolytica hypothetical protein 0.0193 0.0266 0.0408
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0128 0.0149 0.0227
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0068 0.0038 0.0035
Entamoeba histolytica hypothetical protein 0.0167 0.022 0.0337
Echinococcus multilocularis insulin receptor 0.0261 0.0391 0.0388
Brugia malayi Protein kinase domain containing protein 0.0174 0.0233 0.0359
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0167 0.022 0.0334
Echinococcus granulosus casein kinase I delta 0.0093 0.0083 0.008
Schistosoma mansoni hypothetical protein 0.0115 0.0124 0.0124
Schistosoma mansoni ephrin receptor 0.0096 0.009 0.009
Echinococcus multilocularis Immunoglobulin 0.01 0.0096 0.0093
Leishmania major protein kinase, putative 0.0069 0.004 0.0069
Trypanosoma brucei cdc2-related kinase 3 0.0061 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0074 0.005 0.0056
Schistosoma mansoni serine/threonine kinase 0.0206 0.029 0.029
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0065 0.0032 0.0029
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0534 0.0889 0.1019
Onchocerca volvulus 0.0074 0.0048 0.0303
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0174 0.0233 0.0266
Brugia malayi Protein kinase domain containing protein 0.0098 0.0093 0.0143
Entamoeba histolytica protein kinase, putative 0.0128 0.0149 0.0227
Loa Loa (eye worm) hypothetical protein 0.0202 0.0284 0.0324
Echinococcus multilocularis roundabout 2 0.0051 0.0006 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0402 0.0648 0.0976
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0077 0.0055 0.0062
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Mycobacterium leprae conserved hypothetical protein 0.0167 0.022 0.5
Echinococcus multilocularis roundabout 2 0.0051 0.0006 0.0003
Loa Loa (eye worm) AUR protein kinase 0.0128 0.0149 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0233 0.0233
Brugia malayi Serine/threonine-protein kinase SULU 0.0203 0.0285 0.0439
Brugia malayi Immunoglobulin I-set domain containing protein 0.0161 0.0209 0.0322
Echinococcus granulosus N chimaerin 0.0058 0.002 0.0016
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0108 0.0111 0.0126
Loa Loa (eye worm) AUR protein kinase 0.0128 0.0149 0.0169
Trypanosoma cruzi serine carboxypeptidase (CBP1), putative 0.0746 0.1277 0.1965
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0402 0.0648 0.2972
Echinococcus multilocularis casein kinase i 0.0093 0.0083 0.008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0601 0.1012 0.1562
Leishmania major protein kinase, putative 0.0128 0.0149 0.0505
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0112 0.0119 0.0178
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0112 0.0119 0.0384
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0051 0.0006 0.0006
Echinococcus multilocularis lysosomal protective protein 0.0746 0.1277 0.1274
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0128 0.0149 0.1645
Brugia malayi Protein kinase domain containing protein 0.0202 0.0284 0.0438
Trichomonas vaginalis PIKK family atypical protein kinase 0.0304 0.0469 0.0698
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0044 0.0044
Echinococcus granulosus aurora kinase A 0.0128 0.0149 0.0145
Brugia malayi Protein kinase domain containing protein 0.0084 0.0067 0.0104
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0079 0.0057 0.0065
Echinococcus granulosus tyrosine protein kinase Src42A 0.0162 0.0211 0.0207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0006 0.001
Schistosoma mansoni nck2/grb4 0.008 0.0061 0.0061
Echinococcus granulosus TGF-beta receptor type-1 0.0089 0.0076 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Echinococcus granulosus calcium dependent protein kinase 0.0051 0.0008 0.0004
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0203 0.0285 0.0281
Entamoeba histolytica protein kinase, putative 0.0112 0.0119 0.0181
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0078 0.0056 0.0053
Brugia malayi hypothetical protein 0.0084 0.0067 0.0104
Brugia malayi Cytochrome P450 family protein 0.0048 0.0001 0.0002
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0136 0.0163 0.1533
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0097 0.0091 0.0403
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0097 0.0091 0.014
Loa Loa (eye worm) hypothetical protein 0.0062 0.0027 0.003
Echinococcus granulosus activated cdc42 kinase 1 0.0202 0.0284 0.028
Loa Loa (eye worm) hypothetical protein 0.011 0.0115 0.0131
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0058 0.002 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.007 0.0042 0.0048
Schistosoma mansoni serine/threonine kinase 0.0057 0.0017 0.0017
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0903 0.1564 0.1793
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0285 0.0285
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0062 0.0027 0.004
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0176 0.0236 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0402 0.0648 0.0976
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.061 0.0917
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0017 0.0017
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0534 0.0889 0.9506
Schistosoma mansoni hypothetical protein 0.0099 0.0095 0.0095
Loa Loa (eye worm) phosphatidylinositol 3 0.0192 0.0265 0.0303
Echinococcus granulosus epidermal growth factor receptor 0.0394 0.0634 0.0631
Echinococcus multilocularis Zinc finger, PHD finger 0.0534 0.0889 0.0886
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0411 0.0665 0.0662
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0402 0.0648 0.252
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0237 0.0346 0.0343
Giardia lamblia Kinase, CMGC GSK 0.0112 0.0119 0.0359
Brugia malayi RNA binding protein 0.0062 0.0027 0.0042
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0112 0.0119 0.0135
Loa Loa (eye worm) hypothetical protein 0.0283 0.043 0.0493
Brugia malayi Variant SH3 domain containing protein 0.008 0.0061 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0287 0.0438 0.065
Entamoeba histolytica protein kinase domain containing protein 0.0193 0.0266 0.0408
Loa Loa (eye worm) hypothetical protein 0.0062 0.0027 0.003
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0135 0.016 0.0157
Echinococcus multilocularis dual specificity 0.0193 0.0266 0.0262
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Brugia malayi hypothetical protein 0.0231 0.0336 0.0519
Loa Loa (eye worm) hypothetical protein 0.01 0.0096 0.0109
Plasmodium vivax glycogen synthase kinase 3, putative 0.0112 0.0119 0.1308
Entamoeba histolytica PH domain containing protein kinase, putative 0.01 0.0097 0.0147
Brugia malayi Protein kinase domain containing protein 0.0193 0.0266 0.041
Onchocerca volvulus 0.0167 0.022 0.138
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0167 0.022 0.0339
Loa Loa (eye worm) hypothetical protein 0.0472 0.0777 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0167 0.022 0.0313
Echinococcus granulosus mitogen activated protein kinase 11 0.0142 0.0173 0.0169
Brugia malayi casein kinase I 0.0093 0.0083 0.0128
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.007 0.0041 0.0046
Plasmodium falciparum NIMA related kinase 1 0.0119 0.0132 0.1254
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0163 0.0163
Leishmania major protein kinase A catalytic subunit isoform 1 0.0097 0.0091 0.0272
Loa Loa (eye worm) phosphatidylinositol 3 0.0381 0.061 0.0698
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0093 0.0083 0.0094
Echinococcus granulosus casein kinase I delta 0.0093 0.0083 0.008
Loa Loa (eye worm) hypothetical protein 0.1282 0.2256 0.2588
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0381 0.061 0.2795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0284 0.0433 0.0644
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0093 0.0083 0.0094
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0112 0.0119 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0149 0.0149
Brugia malayi Protein kinase domain containing protein 0.0541 0.0903 0.1392
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0097 0.0091 0.0103
Echinococcus multilocularis NCK adaptor protein 0.0085 0.0068 0.0065
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0051 0.0006 0.0003
Trypanosoma cruzi casein kinase, putative 0.0093 0.0083 0.0123
Entamoeba histolytica cell division protein kinase 2, putative 0.0061 0.0025 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0043 0.004
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0192 0.0265 0.1204
Echinococcus multilocularis dual specificity protein kinase clk2 0.0136 0.0163 0.016
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.3596 0.6483 1
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0093 0.0083 0.0094
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0411 0.0665 0.1021
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0128 0.0149 0.0227
Onchocerca volvulus 0.0284 0.0433 0.2719
Leishmania major phosphatidylinositol 3-kinase, putative 0.0534 0.0889 0.349
Trypanosoma brucei protein kinase, putative 0.006 0.0023 0.0092
Entamoeba histolytica protein kinase, putative 0.0193 0.0266 0.0408
Loa Loa (eye worm) TK/ALK protein kinase 0.0541 0.0902 0.1034
Entamoeba histolytica protein kinase, putative 0.0083 0.0066 0.01
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0266 0.0399 0.0396
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1236 0.2173 0.3334
Echinococcus granulosus protein kinase 0.0077 0.0055 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0025 0.0025
Echinococcus multilocularis cyclin dependent kinase 5 0.0061 0.0025 0.0021
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0142 0.0173 0.0261
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.1236 0.2173 0.3348
Brugia malayi p70 ribosomal S6 kinase beta 0.0083 0.0066 0.0102
Onchocerca volvulus 0.0919 0.1593 1
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0083 0.0083
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0411 0.0665 0.1021
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0144 0.0177 0.0202
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0211 0.03 0.0296
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0237 0.0346 0.0343
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0025 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0025 0.0012
Entamoeba histolytica PH domain containing protein kinase, putative 0.0049 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0084 0.0067 0.0104
Loa Loa (eye worm) CAMK protein kinase 0.0053 0.0011 0.0012
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0496 0.082 0.0816
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0381 0.061 0.0936
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0025 0.0012
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0128 0.0149 0.0227
Plasmodium vivax protein kinase Crk2 0.0061 0.0025 0.0249
Schistosoma mansoni ephrin receptor 0.0051 0.0007 0.0007
Trypanosoma cruzi serine peptidase, Clan SC, Family S10, putative 0.0746 0.1277 0.1965
Loa Loa (eye worm) hypothetical protein 0.0049 0.0003 0.0003
Brugia malayi FAT domain containing protein 0.0115 0.0124 0.0192
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Loa Loa (eye worm) hypothetical protein 0.0108 0.011 0.0125
Leishmania major hypothetical protein, unknown function 0.0167 0.022 0.0792
Giardia lamblia Kinase, STE STE20 0.0069 0.004 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0112 0.0119 0.1046
Echinococcus multilocularis Immunoglobulin 0.01 0.0096 0.0093
Brugia malayi Kinase associated domain 1 family protein 0.0099 0.0095 0.0146
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0128 0.0149 0.0145
Loa Loa (eye worm) CAMKK/META protein kinase 0.0071 0.0043 0.0048
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0132 0.0154 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0283 0.043 0.0639
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0192 0.0265 0.0261
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.0119 0.0181
Plasmodium vivax casein kinase 1, putative 0.0093 0.0083 0.0907
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0057 0.0017 0.0014
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0053 0.0011 0.0012
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.01 0.0096 0.0096
Echinococcus multilocularis 0.0077 0.0055 0.0052
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0083 0.0065 0.0062
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0197 0.0274 1
Schistosoma mansoni hypothetical protein 0.0167 0.022 0.022
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0558 0.0934 1
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0112 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0091 0.0091
Echinococcus granulosus TGF beta receptor type 1 0.0089 0.0076 0.0073
Entamoeba histolytica protein kinase, putative 0.0156 0.0199 0.0305
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0076 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.0052 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0093 0.0118
Echinococcus granulosus tyrosine protein kinase HCK 0.0156 0.0199 0.0196
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0162 0.0211 0.0207
Trypanosoma cruzi casein kinase, putative 0.0093 0.0083 0.0123
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0057 0.0017 0.0014
Echinococcus multilocularis tyrosine protein kinase Abl 0.0279 0.0423 0.042
Echinococcus multilocularis casein kinase I delta 0.0093 0.0083 0.008
Echinococcus granulosus roundabout 2 0.0051 0.0006 0.0003
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0381 0.061 0.2364
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.3596 0.6483 1
Echinococcus multilocularis serine:threonine protein kinase 0.0098 0.0093 0.0089
Brugia malayi Furin-like cysteine rich region family protein 0.0394 0.0634 0.0978
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0174 0.0233 0.0359
Onchocerca volvulus Tyrosine kinase homolog 0.0509 0.0844 0.5298
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0017 0.0017
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0093 0.0118
Schistosoma mansoni cell adhesion molecule 0.0126 0.0145 0.0145
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0108 0.0111 0.0171
Echinococcus granulosus twitchin 0.0143 0.0174 0.0171
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0097 0.0091 0.0135
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0057 0.0017 0.0018
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0078 0.0056 0.0053
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.007 0.0042 0.0179
Entamoeba histolytica protein kinase, putative 0.0193 0.0266 0.0408
Schistosoma mansoni ste20-related kinase 0.0186 0.0255 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Echinococcus granulosus serine:threonine protein kinase 0.0098 0.0093 0.0089
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0136 0.0163 0.0735
Echinococcus granulosus Protein kinase C brain isozyme 0.0071 0.0044 0.0041
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0094 0.0085 0.0097
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0071 0.0044 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Entamoeba histolytica protein kinase, putative 0.0087 0.0072 0.0109
Plasmodium falciparum glycogen synthase kinase 3 0.0112 0.0119 0.11
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0266 0.0399 0.0611
Echinococcus multilocularis tyrosine protein kinase 0.0274 0.0415 0.0411
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0119 0.0157
Echinococcus multilocularis calcium dependent protein kinase 0.0051 0.0008 0.0004
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0283 0.043 0.4468
Echinococcus granulosus serine:threonine protein kinase N2 0.0057 0.0017 0.0014
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.552 1 1
Trypanosoma brucei protein kinase, putative 0.0112 0.0119 0.0531
Toxoplasma gondii aurora kinase 0.0128 0.0149 0.1374
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Loa Loa (eye worm) hypothetical protein 0.0103 0.0102 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0296 0.0455 0.0677
Echinococcus granulosus tyrosine protein kinase Fyn 0.0237 0.0346 0.0343
Echinococcus multilocularis roundabout 2 0.015 0.0189 0.0185
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0193 0.0266 0.0978
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0083 0.0065 0.0062
Mycobacterium ulcerans epoxide hydrolase EphA 0.0197 0.0274 0.5
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0237 0.0346 0.0343
Schistosoma mansoni cell adhesion molecule 0.0051 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0274 0.0274
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0061 0.0025 0.0027
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0023 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0534 0.0889 0.0886
Loa Loa (eye worm) hypothetical protein 0.0116 0.0126 0.0143
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Plasmodium vivax hypothetical protein 0.0167 0.022 0.2448
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.2313 0.4141 0.4139
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0127 0.0145
Brugia malayi bone morphogenetic protein type 1 receptor 0.0111 0.0116 0.0179
Echinococcus granulosus epidermal growth factor receptor 0.0256 0.0382 0.0379
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0065 0.0032 0.0029
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0042 0.0039
Echinococcus granulosus casein kinase I alpha 0.0093 0.0083 0.008
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0381 0.061 0.0936
Loa Loa (eye worm) phosphatidylinositol 3 0.0411 0.0665 0.0762
Trypanosoma brucei aurora B kinase 0.0128 0.0149 0.0669
Onchocerca volvulus 0.0084 0.0067 0.0423
Echinococcus granulosus casein kinase i 0.0093 0.0083 0.008
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0103 0.0102 0.0099
Schistosoma mansoni protein kinase 0.0077 0.0055 0.0055
Trichomonas vaginalis AGC family protein kinase 0.006 0.0023 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0124 0.0166
Schistosoma mansoni protein kinase 0.0178 0.024 0.024
Loa Loa (eye worm) TK protein kinase 0.0161 0.0209 0.0238
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0534 0.0889 0.1348
Echinococcus granulosus tyrosine protein kinase Lyn 0.0256 0.0381 0.0377
Echinococcus granulosus serine protein kinase ATM 0.0266 0.0399 0.0396
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0042 0.0039
Brugia malayi Protein kinase domain containing protein 0.0084 0.0067 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0042 0.0039
Onchocerca volvulus 0.006 0.0023 0.0142
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0411 0.0665 0.1024
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0027 0.0024
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0115 0.0124 0.0121
Giardia lamblia Kinase, CMGC GSK 0.0112 0.0119 0.0359
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.1925 0.3431 0.5292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0284 0.0433 0.0644
Schistosoma mansoni hypothetical protein 0.0049 0.0003 0.0003
Brugia malayi protein kinase C II. 0.0071 0.0044 0.0068
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.007 0.0042 0.0448
Schistosoma mansoni protein kinase 0.0211 0.03 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0177 0.0177
Giardia lamblia Aurora kinase 0.0128 0.0149 0.0452
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0043 0.004
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0193 0.0266 0.0405
Onchocerca volvulus 0.0074 0.005 0.0311
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0133 0.0156 0.0153
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.2518 0.4515 0.6956
Leishmania major protein kinase A catalytic subunit isoform 2 0.0097 0.0091 0.0272
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0061 0.0025 0.0006
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0144 0.0177 0.0273
Loa Loa (eye worm) AGC/PKA protein kinase 0.0097 0.0091 0.0103
Loa Loa (eye worm) AUR protein kinase 0.0128 0.0149 0.0169
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0266 0.0399 0.0614
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0193 0.0266 0.121
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.552 1 1
Brugia malayi RhoGAP domain containing protein 0.0058 0.002 0.003
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0072 0.0085
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0197 0.0274 0.027
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0027 0.0027
Schistosoma mansoni protein kinase 0.0163 0.0212 0.0212
Echinococcus granulosus activated cdc42 kinase 1 0.0202 0.0284 0.028
Brugia malayi cell division control protein 2 homolog 0.0061 0.0025 0.0038
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0237 0.0346 0.0343
Brugia malayi Protein kinase domain containing protein 0.0084 0.0067 0.0104
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0097 0.0091 0.0779
Echinococcus multilocularis serine threonine protein kinase 0.0057 0.0017 0.0014
Leishmania major phosphatidylinositol 3-kinase, putative 0.0381 0.061 0.2364
Loa Loa (eye worm) SRC-1 0.0237 0.0346 0.0396
Loa Loa (eye worm) phosphatidylinositol 3 0.0167 0.022 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Toxoplasma gondii FATC domain-containing protein 0.0266 0.0399 0.4127
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0135 0.016 0.0247
Echinococcus multilocularis calcium:calmodulin dependent protein kinase 0.0071 0.0043 0.004
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.0336 0.0333
Echinococcus granulosus serine/threonine protein kinase 0.0049 0.0003 0.00000032954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0665 0.1002
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.1816 0.3231 1
Giardia lamblia Kinase, STE STE20 0.0163 0.0212 0.0649
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.007 0.0042 0.0448
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0069 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0135 0.016 0.0183
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0137 0.0165 0.0161
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0049 0.0003 0.0003
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0061 0.0025 0.0021
Echinococcus granulosus NCK adaptor protein 0.008 0.0061 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Loa Loa (eye worm) hypothetical protein 0.0746 0.1277 0.1464
Brugia malayi ephrin receptor 1 precursor 0.0067 0.0036 0.0056
Echinococcus multilocularis tyrosine protein kinase Srms 0.0199 0.0278 0.0275
Echinococcus multilocularis cyclin dependent kinase 1 0.0061 0.0025 0.0021
Brugia malayi Protein kinase domain containing protein 0.0057 0.0017 0.0026
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.007 0.0042 0.0048
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.3693 0.6661 0.666
Echinococcus multilocularis c src tyrosine kinase 0.0121 0.0136 0.0132
Loa Loa (eye worm) TK/EPH protein kinase 0.0112 0.0118 0.0134
Schistosoma mansoni growth factor receptor-bound protein 0.0085 0.0068 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0043 0.004
Schistosoma mansoni cell adhesion molecule 0.0051 0.0006 0.0006
Loa Loa (eye worm) TK/INSR protein kinase 0.0261 0.0391 0.0448
Loa Loa (eye worm) hypothetical protein 0.006 0.0023 0.0025
Brugia malayi Tyrosine-protein kinase abl-1 0.0279 0.0423 0.0653
Loa Loa (eye worm) hypothetical protein 0.0049 0.0003 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0192 0.0265 0.0408
Entamoeba histolytica casein kinase, putative 0.0093 0.0083 0.0126
Echinococcus multilocularis casein kinase I alpha 0.0093 0.0083 0.008
Brugia malayi cyclin-dependent kinase 9 0.0063 0.0029 0.0044
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0534 0.0889 0.349
Trichomonas vaginalis STE family protein kinase 0.0163 0.0212 0.0302
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0167 0.022 0.0339
Brugia malayi SRC-1 0.0237 0.0346 0.0534
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0069 0.004 0.006
Brugia malayi Protein kinase domain containing protein 0.0076 0.0053 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0245 0.0245
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0138 0.0167 0.019
Brugia malayi cyclin-dependent kinase 7 homolog 0.0102 0.0099 0.0153
Echinococcus multilocularis transfer RNA-Thr 0.0202 0.0284 0.028
Brugia malayi STE20-like kinase MST 0.0237 0.0346 0.0534
Loa Loa (eye worm) hypothetical protein 0.0198 0.0276 0.0316
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0237 0.0346 0.0343
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0058 0.002 0.0021
Onchocerca volvulus 0.0058 0.002 0.0127
Echinococcus multilocularis calcium activated potassium channel 0.0118 0.013 0.0126
Echinococcus granulosus tyrosine protein kinase 0.0274 0.0415 0.0411
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0135 0.016 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0006 0.001
Echinococcus granulosus tyrosine protein kinase shark 0.0084 0.0067 0.0064
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0069 0.004 0.006
Schistosoma mansoni rap gtpase-activating protein 0.0049 0.0003 0.0003
Plasmodium falciparum casein kinase 1 0.0093 0.0083 0.0689
Schistosoma mansoni protein kinase C mu 0.0093 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0051 0.0006 0.0006
Schistosoma mansoni tyrosine kinase 0.0081 0.0062 0.0062
Brugia malayi protein C17H12.11 0.006 0.0023 0.0035
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0167 0.022 0.0334
Brugia malayi probable protein kinase 0.0127 0.0145 0.0224
Loa Loa (eye worm) hypothetical protein 0.0117 0.0128 0.0146
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0167 0.022 0.2268
Onchocerca volvulus 0.0303 0.0468 0.2937
Loa Loa (eye worm) AGC/PKA protein kinase 0.0097 0.0091 0.0103
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0138 0.0167 0.0163
Loa Loa (eye worm) TK protein kinase 0.0274 0.0415 0.0475
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0043 0.004
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0174 0.0233 0.0229
Schistosoma mansoni Neurotrimin precursor (hNT) 0.01 0.0096 0.0096
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0051 0.0006 0.0003
Schistosoma mansoni protein kinase 0.0128 0.0149 0.0149
Brugia malayi hypothetical protein 0.0049 0.0003 0.0005
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0167 0.022 0.0216
Trichomonas vaginalis STE family protein kinase 0.0119 0.0132 0.0178
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.007 0.0042 0.0039
Echinococcus granulosus cyclin dependent kinase 0.0061 0.0025 0.0021
Schistosoma mansoni protein kinase 0.0178 0.024 0.024
Loa Loa (eye worm) sex muscle abnormal protein 5 0.008 0.0061 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0266 0.0266
Entamoeba histolytica protein kinase rad3, putative 0.0266 0.0399 0.0614
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0534 0.0889 0.1348
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0411 0.0665 0.3051
Loa Loa (eye worm) TK protein kinase 0.0156 0.0199 0.0227
Trypanosoma cruzi casein kinase, putative 0.0093 0.0083 0.0123
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0237 0.0346 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0177 0.0237 0.034
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0167 0.022 0.2448
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0065 0.0065
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0411 0.0665 0.1024
Loa Loa (eye worm) hypothetical protein 0.0056 0.0015 0.0016
Trypanosoma brucei rac serine-threonine kinase, putative 0.0087 0.0072 0.0316
Plasmodium falciparum serine/threonine protein kinase, putative 0.0128 0.0149 0.1445
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0061 0.0025 0.0006
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0119 0.0132 0.1458
Brugia malayi Protein kinase domain containing protein 0.0919 0.1593 0.2457
Brugia malayi Protein kinase domain containing protein 0.029 0.0444 0.0684
Echinococcus granulosus dual specificity mitogen activated protein 0.0163 0.0212 0.0209
Echinococcus granulosus c src tyrosine kinase 0.0121 0.0136 0.0132
Onchocerca volvulus Uncharacterized serine carboxypeptidase homolog 0.0746 0.1277 0.8018
Trichomonas vaginalis AGC family protein kinase 0.0128 0.0149 0.0203
Giardia lamblia Hypothetical protein 0.0167 0.022 0.0672
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0192 0.0265 0.0403
Loa Loa (eye worm) hypothetical protein 0.0052 0.0008 0.0008
Echinococcus granulosus tyrosine protein kinase Fyn 0.0237 0.0346 0.0343
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0203 0.0285 0.0281
Trypanosoma cruzi target of rapamycin kinase 3 0.0402 0.0648 0.0995
Brugia malayi Protein kinase domain containing protein 0.0261 0.0391 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0085 0.0085
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0197 0.0275 0.0314
Loa Loa (eye worm) RNA binding protein 0.0062 0.0027 0.003
Echinococcus granulosus protein tyrosine kinase 0.0287 0.0438 0.0435
Trypanosoma cruzi serine peptidase, Clan SC, Family S10, putative 0.0746 0.1277 0.1965
Loa Loa (eye worm) hypothetical protein 0.0078 0.0056 0.0063
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0079 0.0057 0.0065
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0534 0.0889 0.1369
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.3693 0.6661 0.666
Plasmodium vivax hypothetical protein, conserved 0.0167 0.022 0.2448
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.0119 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0025 0.0025
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0534 0.0889 1
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0112 0.0119 0.0115
Echinococcus multilocularis serine:threonine protein kinase 3 0.0237 0.0346 0.0343
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0256 0.0382 0.0379
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0167 0.022 0.2156
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0197 0.0274 0.027
Trypanosoma brucei cdc2-related kinase 1 0.0061 0.0025 0.0098
Giardia lamblia Kinase, CK1 Casein kinase 0.0093 0.0083 0.0249
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0534 0.0889 0.1367
Echinococcus multilocularis 0.0192 0.0265 0.0261
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0167 0.022 0.0313
Echinococcus granulosus casein kinase I alpha 0.0093 0.0083 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0468 0.0468
Echinococcus granulosus protein kinase c iota type 0.0071 0.0044 0.0041
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0381 0.061 0.094
Onchocerca volvulus 0.0056 0.0015 0.0096
Brugia malayi serine/threonine kinase 12 0.0128 0.0149 0.0229
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0251 0.0373 0.0369
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0174 0.0233 0.146
Schistosoma mansoni protein kinase 0.0093 0.0083 0.0083
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0101 0.0098 0.0151
Loa Loa (eye worm) gastrulation defective protein 1 0.0128 0.0147 0.0167
Trichomonas vaginalis STE family protein kinase 0.0069 0.004 0.0036
Schistosoma mansoni vav2 0.0061 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0167 0.022 0.022
Onchocerca volvulus 0.0084 0.0067 0.0423
Trypanosoma cruzi hypothetical protein, conserved 0.125 0.2197 0.3386
Onchocerca volvulus 0.0444 0.0725 0.4554
Giardia lamblia Kinase, CMGC CDK 0.0061 0.0025 0.0068
Trypanosoma cruzi cdc2-related kinase 3 0.0061 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.007 0.0041 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0091 0.0091
Trichomonas vaginalis CK1 family protein kinase 0.0093 0.0083 0.0102
Echinococcus multilocularis casein kinase I delta 0.0093 0.0083 0.008
Echinococcus granulosus hypothetical protein 0.0117 0.0128 0.0125
Entamoeba histolytica PH domain containing protein kinase, putative 0.01 0.0097 0.0147
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0266 0.0399 0.1824
Loa Loa (eye worm) hypothetical protein 0.01 0.0096 0.0109
Loa Loa (eye worm) hypothetical protein 0.0174 0.0231 0.0264
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0027 0.0027
Echinococcus multilocularis geminin 0.0166 0.0217 0.0213
Schistosoma mansoni protein kinase 0.0178 0.024 0.024
Leishmania major phosphatidylinositol kinase related protein, putative 0.0167 0.022 0.0792
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3596 0.6483 1
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0065 0.0065
Echinococcus multilocularis tyrosine protein kinase Blk 0.0199 0.0278 0.0275
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0097 0.0091 0.0403
Echinococcus multilocularis casein kinase I alpha 0.0093 0.0083 0.008
Brugia malayi serine/threonine protein kinase 6 0.0128 0.0149 0.0229
Loa Loa (eye worm) AGC/AKT protein kinase 0.0087 0.0072 0.0082
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0136 0.0163 0.0246
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0084 0.0067 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0093 0.0084 0.013
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0142 0.0173 0.0602
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.007 0.0042 0.0209
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0023 0.0034
Onchocerca volvulus 0.0084 0.0067 0.0423
Echinococcus multilocularis ephrin type A receptor 4 A 0.011 0.0114 0.0111
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0167 0.022 0.2156
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0061 0.0025 0.0027
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0112 0.0119 0.0115
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0069 0.004 0.017
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.3596 0.6483 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.04 0.0644 0.0969
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0469 0.0771 0.0767
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Leishmania major protein kinase, putative 0.0136 0.0163 0.0563
Trypanosoma cruzi casein kinase, putative 0.0093 0.0083 0.0123
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1236 0.2173 0.3334
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0119 0.0132 0.1192
Entamoeba histolytica protein kinase, putative 0.007 0.0042 0.0063
Echinococcus granulosus cyclin dependent kinase 1 0.0061 0.0025 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0237 0.0346 0.0343
Onchocerca volvulus 0.0084 0.0067 0.0423
Brugia malayi Cam kinase protein 1 0.007 0.0042 0.0065
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0534 0.0889 0.1371
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0137 0.0165 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.014 0.017 0.0194
Brugia malayi SH2 domain containing protein 0.0084 0.0067 0.0104
Schistosoma mansoni protein kinase 0.0211 0.03 0.03
Schistosoma mansoni tyrosine kinase 0.0215 0.0307 0.0307
Echinococcus granulosus titin 0.0053 0.0011 0.0008
Brugia malayi Protein kinase domain containing protein 0.0274 0.0415 0.064
Plasmodium falciparum calcium-dependent protein kinase 5 0.007 0.0042 0.0219
Plasmodium falciparum calcium-dependent protein kinase 3 0.007 0.0042 0.0219
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0149 0.0227
Loa Loa (eye worm) hypothetical protein 0.0161 0.0209 0.0239
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1236 0.2173 1
Echinococcus multilocularis serine:threonine protein kinase 0.0098 0.0093 0.0089
Echinococcus multilocularis epidermal growth factor receptor 0.0394 0.0634 0.0631
Echinococcus multilocularis epidermal growth factor receptor 0.0256 0.0382 0.0379
Echinococcus granulosus cyclin dependent kinase 7 0.0094 0.0085 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0027 0.0027
Echinococcus granulosus calcium activated potassium channel 0.0118 0.013 0.0126
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0266 0.0399 0.0616
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0534 0.0889 0.1369
Loa Loa (eye worm) hypothetical protein 0.2313 0.4141 0.475
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Echinococcus multilocularis serine:threonine protein kinase N2 0.0057 0.0017 0.0014
Echinococcus multilocularis 0.0117 0.0128 0.0125
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0272 0.041 0.0407
Echinococcus granulosus defective proboscis extension response 0.01 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.014 0.017 0.0194
Toxoplasma gondii target of rapamycin (TOR), putative 0.04 0.0644 0.6814
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0266 0.0399 0.0396
Echinococcus multilocularis protein kinase shaggy 0.0112 0.0119 0.0115
Brugia malayi Serine carboxypeptidase F41C3.5 precursor 0.0746 0.1277 0.197
Echinococcus multilocularis casein kinase I alpha 0.0093 0.0083 0.008
Brugia malayi C1-like domain containing protein 0.0093 0.0084 0.013
Trypanosoma cruzi serine carboxypeptidase (CBP1), putative 0.0746 0.1277 0.1965
Echinococcus multilocularis N chimaerin 0.0058 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.039 0.0627 0.0943
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0132 0.0154 0.0238
Echinococcus multilocularis hypothetical protein 0.0099 0.0095 0.0091
Leishmania major hypothetical protein, conserved 0.1417 0.2503 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1236 0.2173 0.3334
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0136 0.0163 0.0246
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0069 0.004 0.0057
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0167 0.022 0.022
Onchocerca volvulus 0.0078 0.0056 0.035
Loa Loa (eye worm) phosphatidylinositol 3 0.4818 0.8716 1
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0174 0.0233 0.0229
Brugia malayi Protein kinase domain containing protein 0.0111 0.0116 0.0179
Entamoeba histolytica protein kinase, putative 0.0062 0.0027 0.004
Schistosoma mansoni family S10 non-peptidase homologue (S10 family) 0.0746 0.1277 0.1277
Echinococcus multilocularis neuroglian 0.0051 0.0006 0.0003
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0237 0.0346 0.0343
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0237 0.0346 0.0343
Brugia malayi Immunoglobulin I-set domain containing protein 0.0053 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0052 0.0008 0.0008
Brugia malayi Sex muscle abnormal protein 5 0.008 0.0061 0.0094
Trypanosoma brucei serine peptidase, Clan SC, Family S10 0.0746 0.1277 0.5871
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0147 0.0182 0.0207
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0534 0.0889 0.0886
Schistosoma mansoni tyrosine kinase 0.0084 0.0067 0.0067
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0272 0.041 0.0407
Loa Loa (eye worm) TK/EGFR protein kinase 0.0394 0.0634 0.0726
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0084 0.0067 0.0064
Brugia malayi MH2 domain containing protein 0.0117 0.0127 0.0196
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0381 0.061 0.0606
Entamoeba histolytica protein kinase, putative 0.007 0.0042 0.0063
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0178 0.024 0.0236
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0093 0.0084 0.0096
Echinococcus multilocularis titin 0.0053 0.0011 0.0008
Schistosoma mansoni tyrosine kinase 0.0256 0.0382 0.0382
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0534 0.0889 0.0889
Giardia lamblia Kinase, AGC PKA 0.0097 0.0091 0.0273
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1611 0.2857 0.4406
Trypanosoma cruzi Protein kinase B 0.0049 0.0003 0.0000005084
Echinococcus multilocularis cyclin dependent kinase 19 0.0147 0.0182 0.0178
Onchocerca volvulus 0.0093 0.0083 0.0522
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0061 0.0025 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0003 0.0004
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0121 0.0136 0.0136
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0076 0.0053 0.005
Echinococcus multilocularis cyclin dependent kinase 9 0.0071 0.0043 0.0039
Brugia malayi Fibronectin type III domain containing protein 0.011 0.0115 0.0177
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0182 0.0247 0.0243
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0119 0.0157
Brugia malayi Temporarily assigned gene name protein 59 0.0049 0.0003 0.0005
Brugia malayi Hr1 repeat family protein 0.0057 0.0017 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0665 0.1002
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0127 0.0145
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0142 0.0173 0.078
Echinococcus granulosus neuroglian 0.0051 0.0006 0.0003
Schistosoma mansoni serine/threonine-protein kinase 0.0049 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0121 0.0136 0.0136
Echinococcus granulosus ephrin type A receptor 4 A 0.011 0.0114 0.0111
Plasmodium falciparum protein serine/threonine kinase-1 0.0136 0.0163 0.1613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.061 0.0917
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0132 0.0154 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0393 0.0631 0.095
Plasmodium vivax serine/threonine kinase-1, putative 0.0136 0.0163 0.1809
Entamoeba histolytica hypothetical protein 0.0167 0.022 0.0337
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0042 0.0039
Schistosoma mansoni tyrosine kinase 0.0121 0.0136 0.0136
Echinococcus multilocularis TGF beta receptor type 1 0.0089 0.0076 0.0073
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1236 0.2173 0.335
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0211 0.03 0.0296
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0266 0.0399 0.0399
Brugia malayi casein kinase 1, delta 0.0093 0.0083 0.0128
Echinococcus multilocularis rac serine:threonine kinase 0.0049 0.0003 0.00000032954
Loa Loa (eye worm) phosphatidylinositol kinase 0.0167 0.022 0.0251
Schistosoma mansoni hypothetical protein 0.0166 0.0217 0.0217
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0079 0.0057 0.0065
Schistosoma mansoni tyrosine kinase 0.0237 0.0346 0.0346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0266 0.0399 0.0591
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0051 0.0006 0.0006
Schistosoma mansoni vam6/vps39 related 0.0049 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0215 0.0307 0.0307
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0266 0.0399 0.0616
Loa Loa (eye worm) hypothetical protein 0.0233 0.034 0.0389
Brugia malayi Protein kinase domain containing protein 0.0057 0.0017 0.0026
Giardia lamblia Kinase, CMGC CDK 0.0061 0.0025 0.0068
Echinococcus granulosus protein kinase shaggy 0.0112 0.0119 0.0115
Echinococcus multilocularis mitogen activated protein kinase 14 0.0142 0.0173 0.0169
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0094 0.012
Echinococcus granulosus NDR protein kinase 0.0057 0.0017 0.0014
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0093 0.0083 0.0123
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0199 0.0278 0.0275
Giardia lamblia Kinase, NEK 0.0119 0.0132 0.04
Loa Loa (eye worm) TK/FER protein kinase 0.0084 0.0067 0.0076
Echinococcus multilocularis aurora kinase A 0.0128 0.0149 0.0145
Echinococcus granulosus tyrosine protein kinase ABL1 0.0496 0.082 0.0816
Loa Loa (eye worm) hypothetical protein 0.006 0.0023 0.0025
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1236 0.2173 0.335
Brugia malayi protein unc-22 0.0053 0.0011 0.0017
Schistosoma mansoni tyrosine kinase 0.0261 0.0391 0.0391
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Trypanosoma cruzi cdc2-related kinase 1 0.0061 0.0025 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0402 0.0648 0.0976
Schistosoma mansoni fkbp-rapamycin associated protein 0.0266 0.0399 0.0399
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0135 0.016 0.0182
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0097 0.0091 0.0135
Entamoeba histolytica cell division protein kinase 2, putative 0.0068 0.0039 0.0058
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0197 0.0274 0.027
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0097 0.0091 0.0403
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0027 0.0027
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0411 0.0665 0.1026
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0167 0.022 0.0313
Trichomonas vaginalis CK1 family protein kinase 0.0093 0.0083 0.0102
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.087 0.1503 0.4648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0266 0.0399 0.0591
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0071 0.0044 0.0041
Echinococcus granulosus activin receptor type 0.0417 0.0675 0.0672
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0237 0.0346 0.0343
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0534 0.0889 0.0889
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.007 0.0042 0.0209
Toxoplasma gondii casein kinase I 0.0093 0.0083 0.0655
Brugia malayi hypothetical protein 0.0203 0.0285 0.0439
Loa Loa (eye worm) hypothetical protein 0.0084 0.0067 0.0076
Echinococcus granulosus titin 0.0053 0.0011 0.0008
Brugia malayi Protein kinase domain containing protein 0.0079 0.0057 0.0088
Brugia malayi Stress-activated protein kinase jnk-1 0.0469 0.0771 0.1189
Loa Loa (eye worm) phosphatidylinositol 3 0.0167 0.022 0.0251
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0097 0.0091 0.0087
Echinococcus multilocularis serine:threonine protein kinase 38 0.0057 0.0017 0.0014
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0097 0.0091 0.0741
Echinococcus granulosus dual specificity protein kinase clk2 0.0136 0.0163 0.016
Brugia malayi TAR-binding protein 0.0062 0.0027 0.0042
Echinococcus granulosus tyrosine protein kinase Src42A 0.0237 0.0346 0.0343
Onchocerca volvulus 0.0053 0.0011 0.0069
Echinococcus multilocularis tyrosine kinase 0.0084 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0098 0.0093 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0266 0.0399 0.0591
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0198 0.0276 0.0315
Loa Loa (eye worm) AGC/PKN protein kinase 0.0057 0.0017 0.0018
Echinococcus granulosus c-Jun N-terminal kinases 0.0469 0.0771 0.0767
Trypanosoma cruzi cdc2-related kinase 1 0.0061 0.0025 0.0033
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0186 0.0254 0.1154
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0146 0.0146
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0986 0.1715 0.1712
Trichomonas vaginalis STE family protein kinase 0.0163 0.0212 0.0302
Loa Loa (eye worm) hypothetical protein 0.006 0.0023 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0043 0.004
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0167 0.022 0.0216
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0167 0.022 0.0997
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0083 0.0066 0.0074
Giardia lamblia Kinase, AGC AKT 0.0101 0.0098 0.0295
Echinococcus multilocularis mitogen activated protein kinase 11 0.0142 0.0173 0.0169
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0132 0.0154 0.0176
Echinococcus granulosus growth factor receptor bound protein 2 0.0085 0.0068 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0099 0.0095 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0094 0.012
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0163 0.0212 0.0322
Echinococcus multilocularis cyclin dependent kinase 0.0061 0.0025 0.0021
Schistosoma mansoni family S10 unassigned peptidase (S10 family) 0.0746 0.1277 0.1277
Entamoeba histolytica protein kinase domain containing protein 0.0063 0.0029 0.0042
Leishmania major casein kinase, putative 0.0093 0.0083 0.0241
Schistosoma mansoni protein kinase 0.0176 0.0236 0.0236
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0089 0.0076 0.0073
Schistosoma mansoni tyrosine kinase 0.0103 0.0102 0.0102
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0163 0.0212 0.0962
Loa Loa (eye worm) hypothetical protein 0.011 0.0115 0.0131
Echinococcus granulosus protein kinase c epsilon type 0.0071 0.0044 0.0041
Giardia lamblia Kinase, NEK 0.0119 0.0132 0.04
Echinococcus granulosus tyrosine kinase 0.0199 0.0278 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0017 0.0017
Echinococcus multilocularis tyrosine protein kinase HCK 0.0156 0.0199 0.0196
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0411 0.0665 0.2588
Loa Loa (eye worm) hypothetical protein 0.0266 0.0399 0.0457
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0136 0.0163 0.0735
Loa Loa (eye worm) hypothetical protein 0.008 0.0061 0.0069
Loa Loa (eye worm) hypothetical protein 0.0167 0.022 0.0251
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0057 0.0017 0.0014
Toxoplasma gondii AGC kinase 0.0083 0.0066 0.0467
Schistosoma mansoni tyrosine kinase 0.0453 0.0741 0.0741
Brugia malayi protein-tyrosine kinase 0.0199 0.0278 0.0429
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.007 0.0042 0.0209
Schistosoma mansoni serine/threonine-protein kinase 0.0049 0.0003 0.0003
Echinococcus multilocularis protein kinase c iota type 0.0071 0.0044 0.0041
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0534 0.0889 0.0886
Trichomonas vaginalis CK1 family protein kinase 0.0093 0.0083 0.0102
Loa Loa (eye worm) TK/ROR protein kinase 0.0065 0.0032 0.0036
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0601 0.1012 0.116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0009 0.0013
Echinococcus granulosus mitogen activated protein kinase 14 0.0142 0.0173 0.0169
Echinococcus granulosus tyrosine protein kinase Blk 0.0199 0.0278 0.0275
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0381 0.061 0.2795
Schistosoma mansoni vesicular amine transporter 0.01 0.0096 0.0096
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0203 0.0285 0.0326
Loa Loa (eye worm) phosphatidylinositol 3 0.0167 0.022 0.0251
Echinococcus granulosus family S10 non peptidase ue S10 family 0.0672 0.1142 0.1139
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.008 0.0061 0.0061
Schistosoma mansoni titin 0.0053 0.0011 0.0011
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0003 0.0004
Giardia lamblia Phosphatidylinositol 4-kinase 0.0192 0.0265 0.0811
Echinococcus granulosus rho-associated protein kinase 1 0.0303 0.0468 0.0464
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0051 0.0006 0.0003
Leishmania major protein kinase, putative 0.0136 0.0163 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0247 0.0247
Trypanosoma cruzi casein kinase, putative 0.0093 0.0083 0.0123
Trichomonas vaginalis STE family protein kinase 0.0163 0.0212 0.0302
Entamoeba histolytica protein kinase, putative 0.0128 0.0149 0.0227
Echinococcus multilocularis rho associated protein kinase 0.0303 0.0468 0.0464
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2893 0.52 0.802
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0193 0.0266 0.0304
Trypanosoma cruzi cdc2-related kinase 3 0.0061 0.0025 0.0033
Entamoeba histolytica casein kinase 1, putative 0.0093 0.0083 0.0126
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0192 0.0265 0.2787
Schistosoma mansoni nephrin 0.0051 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.061 0.0917
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0132 0.0154 0.0151
Echinococcus granulosus cyclin dependent kinase 9 0.0071 0.0043 0.0039
Brugia malayi Protein kinase domain containing protein 0.0147 0.0182 0.028
Echinococcus granulosus raf serine:threonine protein kinase 0.0056 0.0016 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0091 0.0091
Schistosoma mansoni tyrosine kinase 0.0287 0.0438 0.0438
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0057 0.0017 0.0014
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0136 0.0163 0.0246
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0174 0.0233 0.0266
Schistosoma mansoni kinase 0.0063 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0198 0.0276 0.0425
Loa Loa (eye worm) TK/FAK protein kinase 0.029 0.0444 0.0508
Plasmodium falciparum calcium-dependent protein kinase 4 0.007 0.0042 0.0219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0402 0.0648 0.0976
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0176 0.0236 0.0232
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.3596 0.6483 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0192 0.0265 0.0403
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0115 0.0124 0.0121
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0076 0.0053 0.0049
Echinococcus granulosus cyclin dependent kinase 19 0.0147 0.0182 0.0178
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2313 0.4141 0.6387
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0099 0.0094 0.0091
Loa Loa (eye worm) hypothetical protein 0.0174 0.0231 0.0264
Onchocerca volvulus 0.0167 0.022 0.138

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.9 nM Inhibition of human recombinant soluble epoxide hydrolase by kinetic fluorescent assay ChEMBL. 16949285
IC50 (binding) = 2.9 nM Inhibition of human recombinant soluble epoxide hydrolase by kinetic fluorescent assay ChEMBL. 16949285
Inhibition (binding) = 62 % Inhibition of human recombinant soluble epoxide hydrolase at 100 nM by end-point fluorescent assay ChEMBL. 16949285
Inhibition (binding) = 62 % Inhibition of human recombinant soluble epoxide hydrolase at 100 nM by end-point fluorescent assay ChEMBL. 16949285

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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