Detailed information for compound 437405

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 741.78 | Formula: C41H43NO12
  • H donors: 1 H acceptors: 7 LogP: 4.85 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)O[C@H]1[C@H](OC(=O)c2ccccc2)[C@@]2(C)[C@@H](OC(=O)/C=C/c3ccccc3)C[C@@H]3[C@H]([C@@]2([C@]([C@H]1OC(=O)c1cccnc1)(C)O)OC3(C)C)OC(=O)C
  • InChi: 1S/C41H43NO12/c1-24(43)49-32-34(52-36(46)27-16-11-8-12-17-27)39(5)30(51-31(45)20-19-26-14-9-7-10-15-26)22-29-33(50-25(2)44)41(39,54-38(29,3)4)40(6,48)35(32)53-37(47)28-18-13-21-42-23-28/h7-21,23,29-30,32-35,48H,22H2,1-6H3/b20-19+/t29-,30+,32+,33-,34+,35+,39-,40-,41-/m1/s1
  • InChiKey: KVALLMPODLLLKE-SYHRUHNWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi major facilitator superfamily protein 0.0016 0.0002 0.0002
Brugia malayi hypothetical protein 0.0016 0.0002 0.0002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0028 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0034 0.0054 0.0054
Loa Loa (eye worm) AGC/PKG protein kinase 0.0018 0.0008 0.0008
Brugia malayi Glutamate receptor 1 precursor 0.0029 0.004 0.004
Brugia malayi RE15519p 0.0019 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Echinococcus granulosus neuropeptide receptor 0.0019 0.001 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.001 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0088
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0147 0.0368 0.0368
Loa Loa (eye worm) calpain family protein 1 0.0052 0.0103 0.0103
Treponema pallidum sodium- and chloride- dependent transporter 0.0147 0.0368 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.001 0.001
Leishmania major carbamoyl-phosphate synthase, putative 0.0113 0.0272 0.0755
Schistosoma mansoni neuropeptide receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Schistosoma mansoni calpain C (C02 family) 0.0022 0.0019 0.0019
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.003 0.0041 0.0148
Leishmania major protein kinase, putative 0.0018 0.0008 0.0023
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0159 0.0159
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.001 0.001
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0075 0.0168 0.1176
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0019 0.0088
Onchocerca volvulus 0.0019 0.001 0.0037
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0002 0.0002
Echinococcus granulosus solute carrier family 22 0.0016 0.0002 0.0002
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0948 0.2594 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0022 0.0019 0.0019
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0673 0.1831 1
Onchocerca volvulus 0.0019 0.001 0.0037
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.001 0.001
Leishmania major protein kinase, putative 0.0017 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0074 0.0164 0.0164
Brugia malayi calpain family protein 1 0.0074 0.0164 0.0164
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.001 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0104 0.0104
Echinococcus granulosus g protein coupled receptor 0.0019 0.001 0.001
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.003 0.0041 0.0209
Schistosoma mansoni adenoreceptor 0.0019 0.001 0.001
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.003 0.0041 0.0209
Echinococcus granulosus tar DNA binding protein 0.0072 0.0159 0.0159
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Schistosoma mansoni glucose transport protein 0.0113 0.0273 0.0273
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0046 0.0086 0.0321
Plasmodium vivax methionine aminopeptidase 1a, putative 0.003 0.0041 0.0148
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.0047 0.0088 0.0239
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.0028
Wolbachia endosymbiont of Brugia malayi branched-chain alpha-keto acid dehydrogenase subunit E2 0.0046 0.0086 0.062
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0056 0.0252
Brugia malayi GnHR receptor homolog 0.0019 0.001 0.001
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.001 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0006 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.001 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.003 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Leishmania major glucose transporter, lmgt2 0.0035 0.0056 0.0155
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0046 0.0086 0.0231
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0088
Schistosoma mansoni hypothetical protein 0.0034 0.0054 0.0054
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.0047 0.0088 0.0239
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide acyltransferase E2 component 0.0046 0.0086 0.062
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0074 0.0164 0.0164
Onchocerca volvulus 0.0016 0.0002 0.0009
Echinococcus granulosus calpain A 0.0022 0.0019 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0104 0.0104
Brugia malayi Dopamine receptor 0.0019 0.001 0.001
Plasmodium vivax calpain, putative 0.0022 0.0019 0.0066
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0029 0.004 0.004
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0046 0.0086 0.0238
Brugia malayi calpain 5 0.0022 0.0019 0.0019
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.001 0.001
Plasmodium falciparum transporter, putative 0.0025 0.0028 0.0097
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0177 0.0452 0.315
Brugia malayi ORL1-like opioid receptor 0.0019 0.001 0.001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.001 0.001
Echinococcus multilocularis fmrfamide receptor 0.0019 0.001 0.001
Echinococcus granulosus glutamate receptor 2 0.0044 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.001
Onchocerca volvulus 0.0016 0.0002 0.0009
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0113 0.0272 0.0748
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.007
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0499 0.1345 0.1345
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0499 0.1345 0.7346
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0113 0.0272 0.1228
Echinococcus multilocularis solute carrier family 22 0.0016 0.0002 0.0002
Loa Loa (eye worm) serotonin transporter b 0.0147 0.0368 0.0368
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0499 0.1345 0.3737
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.001 0.001
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0046 0.0086 0.0086
Schistosoma mansoni glucose transport protein 0.0113 0.0273 0.0273
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.001 0.001
Toxoplasma gondii hypothetical protein 0.0025 0.0028 0.007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0177 0.0452 0.2457
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.001 0.001
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Chlamydia trachomatis dihydrolipoamide acetyltransferase 0.0046 0.0086 0.0487
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0056 0.0148
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0046 0.0086 0.0238
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.001 0.001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0054 0.0054
Echinococcus granulosus calpain 7 C02 family 0.0022 0.0019 0.0019
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0499 0.1345 0.1345
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0054 0.0054
Leishmania major kinesin, putative 0.0022 0.0019 0.0054
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0499 0.1345 0.1345
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0102 0.0241 0.0904
Echinococcus multilocularis sex peptide receptor 0.0019 0.001 0.001
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0046 0.0086 0.0086
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0002 0.0011
Echinococcus granulosus calpain A 0.0078 0.0175 0.0175
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0357 0.0952 0.3571
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0019 0.0047
Brugia malayi Serotonin receptor 0.0019 0.001 0.001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0029 0.004 0.004
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0208 0.0536 0.2011
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0046 0.0086 0.0313
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.0082 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0046 0.0086 0.0387
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0078 0.0175 0.0175
Brugia malayi major facilitator superfamily protein 0.0016 0.0002 0.0002
Schistosoma mansoni calpain (C02 family) 0.0022 0.0019 0.0019
Schistosoma mansoni neuropeptide receptor 0.0019 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0177 0.0452 0.0452
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0046 0.0086 0.0238
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0075 0.0168 0.0621
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.001 0.001
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.0082 0.0082
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0046 0.0086 0.0387
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0973 0.2665 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0208 0.0536 0.0536
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0019 0.0047
Echinococcus granulosus nmda type glutamate receptor 0.0105 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0019 0.0047
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0046 0.0086 0.0387
Schistosoma mansoni amine GPCR 0.0019 0.001 0.001
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0973 0.2665 1
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.001 0.001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.001 0.001
Toxoplasma gondii methionine aminopeptidase 0.0047 0.0088 0.0239
Echinococcus granulosus g protein coupled receptor 0.0019 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0113 0.0273 0.0273
Plasmodium vivax methionine aminopeptidase 1b, putative 0.0047 0.0088 0.0332
Echinococcus multilocularis hypothetical protein 0.0022 0.0019 0.0019
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.001 0.001
Echinococcus multilocularis nmda type glutamate receptor 0.0105 0.0249 0.0249
Schistosoma mansoni helicase 0.0069 0.015 0.015
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0075 0.0168 0.3881
Plasmodium falciparum HP12 protein homolog, putative 0.0017 0.0006 0.0013
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.004 0.004
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0046 0.0086 0.0238
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.001 0.001
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0056 0.0201
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0499 0.1345 0.3733
Schistosoma mansoni hypothetical protein 0.0029 0.004 0.004
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0002 0.0002
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0056 0.0201
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.001 0.001
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0028 0.0028
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.001 0.001
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0002 0.0002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0019 0.0088
Schistosoma mansoni ATP-binding cassette transporter 0.0029 0.004 0.004
Plasmodium falciparum carbamoyl phosphate synthetase 0.0113 0.0272 0.1039
Mycobacterium ulcerans methionine aminopeptidase 0.003 0.0041 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma brucei acetyl-CoA carboxylase 0.131 0.36 1
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.001 0.001
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.001 0.001
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0002 0.0002
Schistosoma mansoni glutamate receptor kainate 0.0029 0.004 0.004
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Echinococcus granulosus Biotin lipoyl attachment 0.0046 0.0086 0.0086
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0056 0.0148
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0022 0.0019 0.0088
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.001 0.001
Echinococcus granulosus calpain 5 0.0022 0.0019 0.0019
Echinococcus granulosus solute carrier family 22 0.0016 0.0002 0.0002
Loa Loa (eye worm) BRM protein 0.0044 0.0081 0.0081
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0075 0.0168 0.0904
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.001 0.001
Echinococcus granulosus cGMP dependent protein kinase 0.0018 0.0008 0.0008
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.001 0.001
Onchocerca volvulus 0.0019 0.001 0.0037
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0017 0.0006 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis calpain A 0.0078 0.0175 0.0175
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0018 0.0008 0.0016
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.131 0.36 1
Schistosoma mansoni sugar transporter 0.0016 0.0002 0.0002
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0019 0.0019
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.003 0.0041 0.0106
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0223 0.0579 0.2173
Loa Loa (eye worm) hypothetical protein 0.0147 0.0368 0.0368
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0047 0.0088 0.04
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0028 0.0028
Onchocerca volvulus 0.0019 0.001 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Echinococcus granulosus calpain 0.0022 0.0019 0.0019
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0028 0.0028
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0022 0.0019 0.0047
Chlamydia trachomatis methionine aminopeptidase 0.003 0.0041 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus multilocularis orexin receptor type 2 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0088
Echinococcus multilocularis serotonin transporter 0.0147 0.0368 0.0368
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0028 0.0028
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0177 0.0452 0.3562
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0046 0.0086 0.0321
Echinococcus multilocularis NMDA receptor 0.0029 0.004 0.004
Onchocerca volvulus Putative transporter 0.0016 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0054
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0046 0.0086 0.0345
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0056 0.0201
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0044 0.0082 0.0082
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0499 0.1345 0.5044
Schistosoma mansoni glutamate receptor NMDA 0.0044 0.0082 0.0082
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0499 0.1345 0.1345
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.03 0.0793 0.2967
Schistosoma mansoni amine GPCR 0.0019 0.001 0.001
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.0082 0.0082
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0017 0.0006 0.0015
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.361 1 1
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0047 0.0088 0.04
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0523 0.1413 0.1413
Onchocerca volvulus 0.0016 0.0002 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.003 0.0077
Chlamydia trachomatis biotin carboxylase 0.0453 0.1218 1
Trypanosoma brucei unspecified product 0.0328 0.087 0.2412
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0104 0.0104
Schistosoma mansoni aspartate carbamoyltransferase 0.0113 0.0272 0.0272
Echinococcus granulosus fmrfamide receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.001 0.001
Schistosoma mansoni sodium/chloride dependent transporter 0.0147 0.0368 0.0368
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0056 0.0201
Loa Loa (eye worm) sugar transporter 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) calpain 0.0022 0.0019 0.0019
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.001 0.001
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.001 0.001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.001 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus granulosus sex peptide receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus somatostatin receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0074 0.0164 0.0164
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.03 0.0793 0.2967
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0177 0.0452 0.1687
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.001 0.001
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.001 0.001
Brugia malayi follicle stimulating hormone receptor 0.0019 0.001 0.001
Brugia malayi putative neuropeptide receptor 0.0019 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0104 0.0104
Brugia malayi Methionine aminopeptidase protein type I 0.0047 0.0088 0.0088
Onchocerca volvulus 0.0019 0.001 0.0037
Loa Loa (eye worm) norepinephrine transporter 0.0147 0.0368 0.0368
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0046 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Onchocerca volvulus 0.0025 0.0028 0.0104
Onchocerca volvulus 0.0016 0.0002 0.0009
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.131 0.36 0.36
Loa Loa (eye worm) glutamate receptor 2 0.0029 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0034 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0056 0.0252
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0159 0.0159
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Brugia malayi larval opioid receptor 0.0019 0.001 0.001
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.001 0.001
Loa Loa (eye worm) solute carrier family 6 member 4 0.0147 0.0368 0.0368
Loa Loa (eye worm) TAR-binding protein 0.0072 0.0159 0.0159
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0019 0.0047
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.0047 0.0088 0.0088
Onchocerca volvulus 0.0019 0.001 0.0037
Echinococcus multilocularis serotonin receptor 0.0019 0.001 0.001
Brugia malayi G protein-coupled receptor 0.0019 0.001 0.001
Onchocerca volvulus 0.0016 0.0002 0.0009
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.0028
Brugia malayi AKH receptor 0.0019 0.001 0.001
Brugia malayi BRM protein 0.0069 0.015 0.015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0104 0.0104
Schistosoma mansoni histamine h1 receptor 0.0019 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0054 0.0054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0088
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0973 0.2665 1
Echinococcus multilocularis g protein coupled receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Onchocerca volvulus 0.0025 0.0028 0.0104
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis solute carrier family 22 0.0016 0.0002 0.0002
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0159 0.0159
Echinococcus granulosus cGMP dependent protein kinase 1 0.0018 0.0008 0.0008
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.001 0.001
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0006 0.0013
Onchocerca volvulus 0.0016 0.0002 0.0009
Onchocerca volvulus 0.0019 0.001 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0046 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0102 0.0241 0.0904
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0177 0.0452 0.1249
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0046 0.0086 0.0086
Mycobacterium ulcerans methionine aminopeptidase MapB 0.003 0.0041 0.0144
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0046 0.0086 0.0231
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0046 0.0086 0.0313
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0046 0.0086 0.0321
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0147 0.0368 0.0368
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0973 0.2665 1
Onchocerca volvulus 0.0019 0.001 0.0037
Echinococcus granulosus glutamate receptor subunit protein glur 0.0029 0.004 0.004
Loa Loa (eye worm) calpain 5 0.0022 0.0019 0.0019
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0104 0.0104
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.001 0.001
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.001 0.001
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0029 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.001 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.001 0.001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0103
Brugia malayi Sugar transporter family protein 0.0016 0.0002 0.0002
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0113 0.0272 0.0272
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Echinococcus multilocularis expressed conserved protein 0.0018 0.0008 0.0008
Brugia malayi hypothetical protein 0.0016 0.0002 0.0002
Schistosoma mansoni pyruvate carboxylase 0.0499 0.1345 0.1345
Schistosoma mansoni opsin-like receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0177 0.0452 0.1687
Toxoplasma gondii methionine aminopeptidase 0.003 0.0041 0.0106
Trypanosoma brucei antigen, putative 0.0022 0.0019 0.0047
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0046 0.0086 0.0321
Schistosoma mansoni amine GPCR 0.0019 0.001 0.001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.026 0.026
Trypanosoma brucei glucose transporter 2A 0.0035 0.0056 0.0148
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0499 0.1345 0.3733
Schistosoma mansoni amine GPCR 0.0019 0.001 0.001
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0046 0.0086 0.0455
Brugia malayi calpain family protein 1 0.0074 0.0164 0.0164
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Echinococcus multilocularis serotonin receptor 0.0019 0.001 0.001
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0028 0.0028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0104 0.0104
Schistosoma mansoni myosin xvIII 0.0019 0.001 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0008 0.0008
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0086 0.0086
Echinococcus granulosus neuropeptide receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Onchocerca volvulus 0.0016 0.0002 0.0009
Echinococcus granulosus serotonin transporter 0.0147 0.0368 0.0368
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0113 0.0272 0.2005
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0046 0.0086 0.0231
Echinococcus multilocularis neuropeptide receptor 0.0019 0.001 0.001
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0046 0.0086 0.0231
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0046 0.0086 0.0231
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0109 0.026 0.026
Brugia malayi Melatonin receptor type 1A 0.0019 0.001 0.001
Onchocerca volvulus 0.0019 0.001 0.0037
Echinococcus granulosus orexin receptor type 2 0.0019 0.001 0.001
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0047 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0074 0.0165 0.0165
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus multilocularis calpain 0.0022 0.0019 0.0019
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.001 0.001
Giardia lamblia DNA repair protein RAD52 0.0357 0.0952 0.3566
Echinococcus granulosus General substrate transporter 0.0097 0.0229 0.0229
Trypanosoma cruzi hypothetical protein, conserved 0.03 0.0793 0.3581
Schistosoma mansoni hypothetical protein 0.0034 0.0054 0.0054
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.001 0.001
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0075 0.0168 0.3881
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Brugia malayi TAR-binding protein 0.0072 0.0159 0.0159
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.003 0.0136
Echinococcus granulosus allatostatin A receptor 0.0019 0.001 0.001
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0028 0.0028
Schistosoma mansoni opsin-like receptor 0.0019 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0026 0.003 0.0084
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0019 0.0019
Toxoplasma gondii hypothetical protein 0.0025 0.0028 0.007
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0046 0.0086 0.0086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.001 0.001
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0017 0.0006 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.001 0.0037
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus dual specificity mitogen activated protein 0.361 1 1
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0177 0.0452 0.0452
Trypanosoma cruzi kinesin, putative 0.0022 0.0019 0.0088
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0046 0.0086 0.0387
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0006 0.0026
Brugia malayi neuropeptide F receptor 0.0019 0.001 0.001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.001 0.001
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0002 0.0011
Schistosoma mansoni neuropeptide receptor 0.0019 0.001 0.001
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0105 0.0249 0.0249
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.1264 0.3473 0.3473
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.001 0.001
Echinococcus granulosus solute carrier family 22 0.0016 0.0002 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0165 0.0165
Brugia malayi Egg laying defective protein 4 0.0018 0.0008 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.001 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0104 0.0104
Echinococcus multilocularis global transcription activator snf2l2 0.0069 0.015 0.015
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0046 0.0086 0.0487
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Brugia malayi Sugar transporter family protein 0.0113 0.0273 0.0273
Echinococcus multilocularis GPCR, family 2 0.0034 0.0054 0.0054
Trypanosoma cruzi hexose transporter 0.0035 0.0056 0.0252
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0019 0.001 0.001
Echinococcus granulosus g protein coupled receptor 0.0019 0.001 0.001
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0113 0.0272 0.1228
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0002 0.0007
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.001 0.001
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0046 0.0086 0.0387
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.0159 0.0159
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0177 0.0452 0.2041
Toxoplasma gondii calcium-dependent protein kinase 0.0017 0.0006 0.0011
Echinococcus granulosus hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus glutamate NMDA receptor subunit 0.0029 0.004 0.004
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0177 0.0452 0.1687
Onchocerca volvulus 0.0016 0.0002 0.0009
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.0082 0.0082
Echinococcus multilocularis glutamate receptor 2 0.0029 0.004 0.004
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.131 0.36 0.36
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0973 0.2665 1
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0177 0.0452 0.3345
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0177 0.0452 0.1687
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0056 0.0201
Toxoplasma gondii carbamoylphosphate synthetase 0.0113 0.0272 0.0748
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0054 0.0054
Echinococcus multilocularis calpain family protein 1, d 0.0052 0.0103 0.0103
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.003 0.0077
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0177 0.0452 0.315
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0499 0.1345 0.5044
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0008 0.0008
Toxoplasma gondii hypothetical protein 0.0017 0.0006 0.001
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0078 0.0175 0.0175
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0177 0.0452 0.1254
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Brugia malayi RNA binding protein 0.0072 0.0159 0.0159
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0019 0.0088
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0046 0.0086 0.0455
Onchocerca volvulus 0.0016 0.0002 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0273 0.1017
Leishmania major glucose transporter, lmgt1 0.0035 0.0056 0.0155
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0046 0.0086 0.0231
Trypanosoma cruzi acetyl-CoA carboxylase 0.0811 0.2213 1
Echinococcus granulosus g-protein coupled receptor 0.0019 0.001 0.001
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0499 0.1345 0.7346
Schistosoma mansoni sugar transporter 0.0016 0.0002 0.0002
Onchocerca volvulus 0.0016 0.0002 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0006 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.003 0.0136
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.001 0.001
Onchocerca volvulus 0.0016 0.0002 0.0009
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0012 0.0052
Onchocerca volvulus 0.0019 0.001 0.0037
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0019 0.0088
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.003 0.0041 0.0041
Onchocerca volvulus 0.0052 0.0103 0.0386
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0046 0.0086 0.0086
Echinococcus granulosus serotonin receptor 0.0019 0.001 0.001
Echinococcus multilocularis General substrate transporter 0.0097 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0002 0.0002
Onchocerca volvulus 0.0025 0.0028 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0047
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0177 0.0452 0.2041
Loa Loa (eye worm) calpain family protein 1 0.0074 0.0164 0.0164
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0028 0.0028
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.0047 0.0088 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Brugia malayi hypothetical protein 0.0016 0.0002 0.0002
Plasmodium falciparum cGMP-dependent protein kinase 0.0018 0.0008 0.0022
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0047 0.0088 0.0246
Onchocerca volvulus 0.0019 0.001 0.0037
Onchocerca volvulus 0.0016 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.001 0.001
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0973 0.2665 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.001 0.001
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0177 0.0452 0.2041
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0973 0.2665 1
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Entamoeba histolytica protein kinase, putative 0.0036 0.0057 0.0214
Echinococcus multilocularis allatostatin A receptor 0.0019 0.001 0.001
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0078 0.0175 0.0175
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.001 0.001
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.001 0.001
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.001 0.001
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0028 0.0028
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.03 0.0793 0.2196
Schistosoma mansoni glutamate receptor kainate 0.0029 0.004 0.004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0147 0.0368 0.0368
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0056 0.0155
Brugia malayi N-terminal motif family protein 0.0208 0.0536 0.0536
Trypanosoma brucei kinesin, putative 0.0022 0.0019 0.0047
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0973 0.2665 1
Loa Loa (eye worm) BRM protein 0.0036 0.0057 0.0057
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.001 0.001
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0973 0.2665 0.2665
Loa Loa (eye worm) RNA binding protein 0.0072 0.0159 0.0159
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0029 0.004 0.004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.001 0.001
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0029 0.004 0.004
Schistosoma mansoni Mername-AA248 (C02 family) 0.0022 0.0019 0.0019
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0056 0.0201
Echinococcus granulosus neuropeptide s receptor 0.0019 0.001 0.001
Onchocerca volvulus 0.0016 0.0002 0.0009
Brugia malayi sulfakinin receptor protein 0.0019 0.001 0.001
Loa Loa (eye worm) sugar transporter 0.0113 0.0273 0.0273
Schistosoma mansoni acetyl-CoA carboxylase 0.131 0.36 0.36
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.001 0.001
Entamoeba histolytica calpain large subunit domain III containing protein 0.0022 0.0019 0.0073
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0046 0.0086 0.0487
Schistosoma mansoni protein kinase 0.361 1 1
Onchocerca volvulus 0.0019 0.001 0.0037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0054
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0499 0.1345 1
Schistosoma mansoni neuropeptide receptor 0.0019 0.001 0.001
Echinococcus multilocularis g protein coupled receptor 0.0019 0.001 0.001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.001 0.001
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0028 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.03 0.0793 0.3581
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.004 0.004
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.003 0.0041 0.0285
Schistosoma mansoni glucose transport protein 0.0113 0.0273 0.0273
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.001 0.001
Trypanosoma cruzi kinesin, putative 0.0022 0.0019 0.0088
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0019 0.001 0.001
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0113 0.0273 0.0273
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0177 0.0452 0.315
Brugia malayi Sugar transporter family protein 0.0016 0.0002 0.0002
Plasmodium vivax hexose transporter 0.0113 0.0273 0.1045
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0177 0.0452 0.1254
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0028 0.0097
Echinococcus granulosus tm gpcr rhodopsin 0.0523 0.1413 0.1413
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0499 0.1345 0.608
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.003 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.001 0.001
Mycobacterium ulcerans hypothetical protein 0.0046 0.0086 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.003 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.001 0.001
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0223 0.0579 0.2166
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0028 0.0028
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.001 0.001
Echinococcus multilocularis solute carrier family 22 0.0016 0.0002 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Onchocerca volvulus 0.0019 0.001 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus granulosus cGMP dependent protein kinase 1 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.001 0.001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.001 0.001
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0046 0.0086 0.0086
Trypanosoma brucei glucose transporter 1E 0.0035 0.0056 0.0148
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0002 0.0011
Brugia malayi Dopamine receptor protein 1 0.0019 0.001 0.001
Loa Loa (eye worm) methionine aminopeptidase type I 0.0047 0.0088 0.0088
Brugia malayi Dopamine receptor protein 2 0.0019 0.001 0.001
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0028 0.0028
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0028 0.0028
Schistosoma mansoni sodium/chloride dependent transporter 0.0039 0.0065 0.0065
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0028 0.0028
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.001 0.001
Onchocerca volvulus 0.0016 0.0002 0.0009
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0029 0.004 0.004
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0029 0.004 0.004
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0046 0.0086 0.0231
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.001 0.001
Schistosoma mansoni glucose transporter 0.0016 0.0002 0.0002
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0973 0.2665 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Leishmania major carboxylase, putative 0.0499 0.1345 0.3737
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0046 0.0086 0.0086
Brugia malayi hypothetical protein 0.0017 0.0005 0.0005
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0973 0.2665 1
Echinococcus multilocularis calpain 5 0.0022 0.0019 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.001 0.001
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.001 0.001
Echinococcus multilocularis fmrfamide receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0147 0.0368 0.0368
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0113 0.0272 0.1039
Schistosoma mansoni glutamate receptor kainate 0.0029 0.004 0.004
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.003 0.0107
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0056 0.0252
Brugia malayi neuropeptide F receptor 0.0019 0.001 0.001
Echinococcus granulosus GPCR family 2 0.0034 0.0054 0.0054
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.001 0.001
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.0082 0.0082
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0046 0.0086 0.0455
Brugia malayi hypothetical protein 0.0026 0.003 0.003
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0499 0.1345 1
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis dual specificity mitogen activated protein 0.361 1 1
Schistosoma mansoni amine GPCR 0.0019 0.001 0.001
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0177 0.0452 0.1687
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0019 0.0088
Echinococcus multilocularis somatostatin receptor 0.0019 0.001 0.001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.001 0.001
Brugia malayi Serotonin receptor 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0086 0.0086
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0159 0.0159
Loa Loa (eye worm) glutamate receptor 1 0.0029 0.004 0.004
Treponema pallidum pyruvate carboxylase subunit B 0.0046 0.0086 0.1375
Brugia malayi Carboxyl transferase domain containing protein 0.1264 0.3473 0.3473
Plasmodium vivax amine transporter, putative 0.0025 0.0028 0.0097
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Leishmania major glucose transporter, lmgt3 0.0035 0.0056 0.0155
Onchocerca volvulus 0.0019 0.001 0.0037
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0054
Brugia malayi hypothetical protein 0.0019 0.001 0.001
Onchocerca volvulus 0.0147 0.0368 0.138
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0177 0.0452 0.1249
Leishmania major acetyl-CoA carboxylase, putative 0.131 0.36 1
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0973 0.2665 0.2665
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0177 0.0452 0.0452
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.001 0.001
Echinococcus multilocularis tar DNA binding protein 0.0072 0.0159 0.0159
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0113 0.0272 0.1011
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis neuropeptide receptor 0.0019 0.001 0.001
Trypanosoma brucei glucose transporter, putative 0.0035 0.0056 0.0148
Echinococcus multilocularis Biotin lipoyl attachment 0.0046 0.0086 0.0086
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0046 0.0086 0.0345
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0499 0.1345 0.5044
Schistosoma mansoni sugar transporter 0.0016 0.0002 0.0002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.001 0.001
Echinococcus granulosus global transcription activator snf2l2 0.0069 0.015 0.015
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0056 0.0148
Mycobacterium ulcerans pyruvate carboxylase 0.0499 0.1345 0.5044
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0028
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.026 0.026
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.003 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0074 0.0165 0.0165
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0046 0.0086 0.0231
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.004 0.004
Brugia malayi calpain 7 0.0022 0.0019 0.0019
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0113 0.0272 0.0272
Echinococcus multilocularis g protein coupled receptor 0.0019 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0159 0.0159
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0499 0.1345 0.608
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0177 0.0452 0.1687
Chlamydia trachomatis glutamine binding protein 0.0075 0.0168 0.1176
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0056 0.0201
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.03 0.0793 0.2201
Brugia malayi G-protein coupled receptor 0.0019 0.001 0.001
Trypanosoma brucei methionine aminopeptidase, putative 0.0047 0.0088 0.0239
Onchocerca volvulus 0.0016 0.0002 0.0009
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0046 0.0086 0.0321
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0019 0.0054
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.001 0.001
Plasmodium falciparum hexose transporter 0.0113 0.0273 0.1045
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0046 0.0086 0.0086
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.001 0.001
Leishmania major protein kinase, putative 0.0018 0.0008 0.0023
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0044 0.0082 0.0082
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0046 0.0086 0.0387
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0103
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.131 0.36 1
Schistosoma mansoni sugar transporter 0.0016 0.0002 0.0002
Echinococcus multilocularis solute carrier family 22 0.0016 0.0002 0.0002
Chlamydia trachomatis acetyl-CoA carboxylase biotin carboxyl carrier protein 0.0046 0.0086 0.0487
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0046 0.0086 0.0387
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.001 0.001
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0948 0.2594 1
Schistosoma mansoni opsin-like receptor 0.0019 0.001 0.001
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0002 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0054 0.0054
Onchocerca volvulus 0.0019 0.001 0.0037
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0017 0.0006 0.0016
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.361 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.001 0.001
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0177 0.0452 0.2457
Onchocerca volvulus 0.0019 0.001 0.0037
Onchocerca volvulus 0.0016 0.0002 0.0009
Schistosoma mansoni biogenic amine receptor 0.0019 0.001 0.001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0028 0.0028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0104 0.0104
Toxoplasma gondii pyruvate carboxylase 0.0499 0.1345 0.3733
Brugia malayi Glutamate receptor 2 precursor 0.0029 0.004 0.004
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.001 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.001 0.001
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0046 0.0086 0.0231
Toxoplasma gondii facilitative glucose transporter GT1 0.0113 0.0273 0.0753
Leishmania major hypothetical protein, conserved 0.0016 0.0002 0.0007
Echinococcus multilocularis glutamate receptor 2 0.0044 0.0082 0.0082
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.001 0.001
Onchocerca volvulus 0.0973 0.2665 1
Onchocerca volvulus 0.0019 0.001 0.0037
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0078 0.0175 0.0175
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0028 0.0028
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0046 0.0086 0.0086
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0018 0.0008 0.0008
Brugia malayi hypothetical protein 0.0025 0.0028 0.0028
Echinococcus granulosus solute carrier family 22 0.0016 0.0002 0.0002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0054 0.0054

Activities

Activity type Activity value Assay description Source Reference
Imax (binding) = 100 % Inhibition of human Pgp-mediated DNR transport in NIH3T3 cells by microplate assay ChEMBL. 17850057
Imax (binding) = 100 % Inhibition of human Pgp-mediated DNR transport in NIH3T3 cells by microplate assay ChEMBL. 17850057
Ki (binding) = -4.6 Inhibition of human Pgp-mediated DNR transport in NIH3T3 cells by microplate assay ChEMBL. 17850057
Ki (binding) = 25.04 uM Inhibition of human Pgp-mediated DNR transport in NIH3T3 cells by microplate assay ChEMBL. 17850057
Ki (binding) = 25.04 uM Inhibition of human Pgp-mediated DNR transport in NIH3T3 cells by microplate assay ChEMBL. 17850057
Log Ki (binding) = 4.6 Inhibition of human Pgp-mediated DNR transport in NIH3T3 cells by microplate assay ChEMBL. 17850057
LogP = 8 Partition coefficient, log P of the compound ChEMBL. 17850057

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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