Detailed information for compound 546304

Basic information

Technical information
  • TDR Targets ID: 546304
  • Name: N-[(3,4,5-triphenylcyclohex-2-en-1-ylidene)am ino]aniline
  • MW: 414.541 | Formula: C30H26N2
  • H donors: 1 H acceptors: 0 LogP: 7.07 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)N/N=C\1/CC(c2ccccc2)C(C(=C1)c1ccccc1)c1ccccc1
  • InChi: 1S/C30H26N2/c1-5-13-23(14-6-1)28-21-27(32-31-26-19-11-4-12-20-26)22-29(24-15-7-2-8-16-24)30(28)25-17-9-3-10-18-25/h1-21,29-31H,22H2
  • InChiKey: ZXQLPFHZTSVVFY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[(3,4,5-triphenyl-1-cyclohex-2-enylidene)amino]aniline
  • phenyl-[(3,4,5-triphenylcyclohex-2-en-1-ylidene)amino]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ABC1 family protein 0.0071 0.0355 0.3048
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0078 0.0404 0.3471
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0136 0.028
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0193 0.0193
Echinococcus granulosus o acyltransferase membrane bound domain 0.0084 0.0441 0.0441
Schistosoma mansoni gabp alpha 0.0084 0.0438 0.0684
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0088 0.0466 0.1157
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0084 0.0441 0.0441
Echinococcus granulosus Aminotransferase class III 0.0088 0.0466 0.0466
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0044 0.0365
Brugia malayi diacylglycerol acyltransferase 0.0084 0.0441 0.0441
Loa Loa (eye worm) MBOAT family protein 0.0974 0.6414 0.6414
Loa Loa (eye worm) hypothetical protein 0.0071 0.0355 0.0355
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0124 0.0124
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0355 0.0881
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0031 0.0253
Loa Loa (eye worm) hypothetical protein 0.0054 0.0243 0.0243
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0038 0.0038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0037 0.0126 0.0197
Plasmodium falciparum glutathione reductase 0.0191 0.116 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0049 0.0204 0.0204
Brugia malayi Pre-SET motif family protein 0.0095 0.0512 0.0512
Toxoplasma gondii histone lysine methyltransferase SET1 0.0178 0.1075 0.9266
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0322 0.2768
Brugia malayi Thioredoxin reductase 0.0191 0.116 0.116
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0078 0.0404 1
Loa Loa (eye worm) hypothetical protein 0.0511 0.3307 0.3307
Brugia malayi SET domain containing protein 0.0019 0.0002 0.0002
Brugia malayi beta-lactamase family protein 0.0071 0.0355 0.0355
Entamoeba histolytica hypothetical protein 0.0036 0.0119 0.2681
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0272 0.0562
Loa Loa (eye worm) hypothetical protein 0.1509 1 1
Echinococcus multilocularis muscleblind protein 0.1509 1 1
Entamoeba histolytica vacuolar protein sorting 26 0.0084 0.0441 1
Echinococcus granulosus chromobox protein 1 0.008 0.0417 0.0417
Brugia malayi hypothetical protein 0.0349 0.2217 0.2217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0486 0.0757
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0084 0.0441 0.3793
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0119 0.0186
Loa Loa (eye worm) hypothetical protein 0.0081 0.0422 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0441 0.0912
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.018 0.0371
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0272 0.2337
Loa Loa (eye worm) CHromoDomain protein family member 0.0021 0.0016 0.0016
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0272 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0201 0.0313
Loa Loa (eye worm) thioredoxin reductase 0.0191 0.116 0.116
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0014 0.0106
Schistosoma mansoni rab6-interacting 0.002 0.0014 0.0022
Mycobacterium ulcerans acetylornithine aminotransferase 0.0088 0.0466 0.1157
Echinococcus granulosus zinc finger protein 0.0028 0.0064 0.0064
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0014 0.0106
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0454 0.2925 0.7288
Echinococcus multilocularis dna polymerase kappa 0.002 0.0014 0.0014
Trypanosoma cruzi glycerol uptake protein, putative 0.0084 0.0441 0.3793
Echinococcus granulosus dna polymerase eta 0.002 0.0014 0.0014
Mycobacterium tuberculosis Conserved protein 0.0071 0.0355 0.0881
Echinococcus granulosus ornithine aminotransferase 0.0088 0.0466 0.0466
Entamoeba histolytica hypothetical protein 0.0084 0.0441 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0436 0.2803 0.6963
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0375 0.0375
Brugia malayi Bromodomain containing protein 0.0092 0.0493 0.0493
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0355 0.0355
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0104 0.0214
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0355 0.0881
Loa Loa (eye worm) histone methyltransferase 0.0032 0.009 0.009
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0084 0.0441 0.0688
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0124 0.1053
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0066 0.0322 0.08
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0014 0.0106
Leishmania major hypothetical protein, conserved 0.0071 0.0355 0.3048
Mycobacterium ulcerans L-lysine aminotransferase 0.0088 0.0466 0.1157
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0088 0.0466 0.1157
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0156 0.0156
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0052 0.0052
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0355 0.0355
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0355 0.0355
Loa Loa (eye worm) doublecortin family protein 0.002 0.0014 0.0014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0404 0.0404
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0355 0.0881
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0404 0.0404
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0512 0.4408
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0014 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0201 0.0313
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0088 0.0466 1
Brugia malayi PHD-finger family protein 0.0034 0.0106 0.0106
Echinococcus granulosus o acyltransferase membrane bound domain 0.0084 0.0441 0.0441
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0124 0.1053
Plasmodium vivax SET domain protein, putative 0.0095 0.0512 0.4408
Onchocerca volvulus 0.0108 0.0601 0.122
Schistosoma mansoni survival motor neuron protein 0.0047 0.0193 0.0301
Echinococcus multilocularis ornithine aminotransferase 0.0088 0.0466 0.0466
Schistosoma mansoni cpg binding protein 0.0098 0.0538 0.0838
Echinococcus granulosus dna polymerase kappa 0.002 0.0014 0.0014
Echinococcus granulosus histone lysine methyltransferase setb 0.0114 0.0644 0.0644
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0084 0.0441 0.3793
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0084 0.0441 0.0441
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0422 0.0657
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0044 0.0365
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0142
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0355 0.0881
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0355 0.0881
Onchocerca volvulus 0.0026 0.0053 0.0081
Onchocerca volvulus Alhambra homolog 0.0034 0.0104 0.0186
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0066 0.0322 0.08
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0014 0.0031
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0272 0.2337
Echinococcus multilocularis expressed protein 0.0039 0.0136 0.0136
Schistosoma mansoni lamin 0.0026 0.0053 0.0083
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0016 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0052 0.0052
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0044 0.0365
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0436 0.2803 0.6985
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0151 0.0151
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0355 0.3048
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0088 0.0466 0.1092
Leishmania major hypothetical protein, conserved 0.0084 0.0441 0.3793
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0039 0.0136 0.0136
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0196 0.1195 0.1864
Echinococcus granulosus zinc finger protein 0.089 0.5851 0.5851
Echinococcus multilocularis lamin 0.0026 0.0053 0.0053
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0002 0.0002
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0039 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0196 0.119 0.1855
Brugia malayi MBOAT family protein 0.0084 0.0441 0.0441
Brugia malayi Bromodomain containing protein 0.0036 0.0122 0.0122
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0071 0.0355 0.0355
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0404 0.3471
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0014 0.0106
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0088 0.0466 0.1157
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0084 0.0441 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0031 0.0253
Brugia malayi PHD-finger family protein 0.0034 0.0104 0.0104
Mycobacterium ulcerans beta-lactamase 0.0071 0.0355 0.0881
Mycobacterium tuberculosis Probable oxidoreductase 0.0485 0.313 0.7799
Mycobacterium tuberculosis Conserved protein 0.0071 0.0355 0.0881
Schistosoma mansoni inositol monophosphatase 0.0037 0.0124 0.0193
Echinococcus multilocularis GA binding protein alpha chain 0.0084 0.0438 0.0438
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0124 0.2629
Schistosoma mansoni chromobox protein 0.008 0.0417 0.065
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0355 0.3048
Entamoeba histolytica hypothetical protein 0.0036 0.0119 0.2681
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0647 0.4222 0.4222
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0417 0.0417
Brugia malayi MBOAT family protein 0.0084 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0071 0.0355 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.004 0.0081
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0512 0.0512
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0031 0.0253
Onchocerca volvulus 0.0026 0.0053 0.0081
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0192 0.0192
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0066 0.0322 0.0503
Onchocerca volvulus 0.0071 0.0355 0.0709
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0404 0.0404
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0124 0.0304
Brugia malayi Pre-SET motif family protein 0.0647 0.4222 0.4222
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.013 0.1112
Plasmodium falciparum phd finger protein, putative 0.0034 0.0104 0.088
Echinococcus multilocularis Aminotransferase class III 0.0088 0.0466 0.0466
Leishmania major glycerol uptake protein, putative 0.0084 0.0441 0.3793
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0044 0.0365
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0355 0.0881
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0104 0.0214
Schistosoma mansoni ap endonuclease 0.0018 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.008 0.0417 0.0863
Echinococcus multilocularis zinc finger protein 0.0028 0.0064 0.0064
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0088 0.0466 1
Onchocerca volvulus 0.0349 0.2217 0.4585
Plasmodium vivax thioredoxin reductase, putative 0.0191 0.116 1
Trypanosoma brucei protein kinase, putative 0.0059 0.0272 0.2337
Echinococcus granulosus geminin 0.0196 0.119 0.119
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0066 0.0322 0.2768
Mycobacterium tuberculosis Probable dehydrogenase 0.0436 0.2803 0.6985
Schistosoma mansoni hypothetical protein 0.0196 0.119 0.1855
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0142 0.0142
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0031 0.0666
Brugia malayi jmjC domain containing protein 0.011 0.0617 0.0617
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0486 0.0486
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0322 0.2768
Trichomonas vaginalis helicase, putative 0.0021 0.0016 0.003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0078 0.0404 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0272 0.0425
Loa Loa (eye worm) beta-lactamase 0.0071 0.0355 0.0355
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0486 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0441 0.0912
Echinococcus granulosus muscleblind protein 0.1509 1 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0038 0.013 0.1112
Giardia lamblia DINP protein human, muc B family 0.002 0.0014 0.0306
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.011 0.0617 0.0617
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0108 0.0601 0.0936
Echinococcus multilocularis thioredoxin glutathione reductase 0.0191 0.116 0.116
Treponema pallidum alginate O-acetylation protein (algI) 0.0084 0.0441 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0124 0.0253
Plasmodium falciparum thioredoxin reductase 0.0191 0.116 1
Loa Loa (eye worm) fli-1 protein 0.0254 0.158 0.158
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0066 0.0322 0.2768
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0616 0.4013 1
Echinococcus multilocularis chromobox protein 1 0.008 0.0417 0.0417
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0104 0.088
Loa Loa (eye worm) hypothetical protein 0.0078 0.0404 0.0404
Trypanosoma brucei glycerol uptake protein, putative 0.0084 0.0441 0.3793
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0272 0.0272
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.004 0.0081
Trypanosoma brucei glycerol uptake protein, putative 0.0084 0.0441 0.3793
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0322 0.2768
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0124 0.2776
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0355 0.3048
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0355 0.0881
Trichomonas vaginalis glutathione reductase, putative 0.0066 0.0322 0.0666
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0044
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0156 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0104 0.0214
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0404 0.0404
Brugia malayi jmjC domain containing protein 0.0048 0.0201 0.0201
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0084 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0084 0.0441 0.0441
Brugia malayi beta-lactamase 0.0071 0.0355 0.0355
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0422 0.0422
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0014 0.0026
Brugia malayi CXXC zinc finger family protein 0.0091 0.0488 0.0488
Brugia malayi Bromodomain containing protein 0.0044 0.0174 0.0174
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0084 0.0441 0.3793
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0486 0.0757
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0124 0.1053
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0088 0.0466 0.1157
Echinococcus granulosus intermediate filament protein 0.0026 0.0053 0.0053
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0486 0.0486
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0106
Echinococcus granulosus lysine specific demethylase 5A 0.0048 0.0201 0.0201
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0084 0.0441 0.0441
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.001 0.001
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0084 0.0441 1
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0355 0.0814
Schistosoma mansoni cpg binding protein 0.0098 0.0538 0.0838
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0192 0.0192
Brugia malayi chromobox protein homolog 3 0.0045 0.018 0.018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0486 0.0486
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0355 0.0553
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0203 0.0418
Leishmania major DNA polymerase kappa, putative 0.002 0.0014 0.0106
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0066 0.0322 0.2768
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0272 0.2337
Loa Loa (eye worm) inositol-1 0.0037 0.0124 0.0124
Brugia malayi Inositol-1 0.0037 0.0124 0.0124
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0044 0.0365
Schistosoma mansoni DNA polymerase eta 0.002 0.0014 0.0022
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0084 0.0441 0.0441
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Schistosoma mansoni hypothetical protein 0.0849 0.5573 0.8688
Echinococcus multilocularis ornithine aminotransferase 0.0088 0.0466 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0272 0.2337
Entamoeba histolytica hypothetical protein 0.0023 0.0031 0.0666
Schistosoma mansoni microtubule-associated protein tau 0.0796 0.522 0.8138
Schistosoma mansoni lozenge 0.0064 0.0308 0.048
Trichomonas vaginalis chromobox protein, putative 0.008 0.0417 0.0863
Brugia malayi F/Y-rich N-terminus family protein 0.0044 0.0176 0.0176
Echinococcus granulosus o acyltransferase membrane bound domain 0.0084 0.0441 0.0441
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0014 0.028
Leishmania major glycerol uptake protein, putative 0.0084 0.0441 0.3793
Onchocerca volvulus 0.0511 0.3307 0.6851
Brugia malayi hypothetical protein 0.002 0.0014 0.0014
Brugia malayi MAP kinase sur-1 0.0059 0.0272 0.0272
Plasmodium vivax glutathione reductase, putative 0.0191 0.116 1
Echinococcus multilocularis chromobox protein 1 0.008 0.0417 0.0417
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0422 0.0422
Echinococcus multilocularis Protein lozenge 0.0064 0.0308 0.0308
Echinococcus multilocularis sterol O acyltransferase 1 0.0084 0.0441 0.0441
Entamoeba histolytica hypothetical protein, conserved 0.0084 0.0441 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0031 0.0631
Loa Loa (eye worm) hypothetical protein 0.0071 0.0355 0.0355
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.011 0.0617 0.0617
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0088 0.0466 0.1157
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0404 0.0835
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Loa Loa (eye worm) hhat protein 0.0084 0.0441 0.0441
Brugia malayi follicle stimulating hormone receptor 0.1419 0.9399 0.9399
Loa Loa (eye worm) hypothetical protein 0.0058 0.0264 0.0264
Mycobacterium ulcerans lipase LipD 0.0071 0.0355 0.0881
Echinococcus multilocularis neuropeptide s receptor 0.0915 0.6019 0.6019
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0104 0.0104
Echinococcus granulosus fetal alzheimer antigen falz 0.0031 0.0087 0.0087
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0088 0.0466 0.1157
Trichomonas vaginalis mercuric reductase, putative 0.0066 0.0322 0.0666
Plasmodium vivax ornithine aminotransferase, putative 0.0088 0.0466 0.4006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0193 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Brugia malayi hypothetical protein 0.002 0.0014 0.0014
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0082 0.0425 0.0425
Brugia malayi beta-lactamase family protein 0.0071 0.0355 0.0355
Echinococcus granulosus ubiquitin specific protease 41 0.0078 0.0404 0.0404
Echinococcus multilocularis musashi 0.0026 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0034 0.0104 0.0161
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0344 0.0344
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0066 0.0322 0.2768
Schistosoma mansoni lamin 0.0026 0.0053 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Schistosoma mansoni jumonji domain containing protein 0.0088 0.0465 0.0725
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0031 0.0073
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0355 0.0881
Onchocerca volvulus 0.0091 0.0488 0.0986
Schistosoma mansoni lipoxygenase 0.002 0.0014 0.0022
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0355 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Brugia malayi hypothetical protein 0.0025 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0044 0.0175 0.0175
Echinococcus multilocularis peregrin 0.0036 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0071 0.0355 0.0355
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.018 0.0345
Mycobacterium tuberculosis Probable reductase 0.0436 0.2803 0.6985
Brugia malayi Hhat protein 0.0084 0.0441 0.0441
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0021 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0404 0.0835
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0084 0.0441 0.0441
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Schistosoma mansoni rotamase 0.0039 0.0136 0.0213
Trichomonas vaginalis esterase, putative 0.0071 0.0355 0.0733
Onchocerca volvulus 0.0035 0.0115 0.0209
Echinococcus multilocularis muscleblind protein 1 0.1509 1 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0014 0.0031
Loa Loa (eye worm) MBOAT family protein 0.0084 0.0441 0.0441
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0124 0.0253
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.013 0.293
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0066 0.0322 0.0322
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0119 0.0119
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0355 0.0733
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0272 0.6732
Leishmania major DNA polymerase eta, putative 0.002 0.0014 0.0106
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0272 0.2337
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0044 0.0365
Brugia malayi glutathione reductase 0.0191 0.116 0.116
Trichomonas vaginalis rotamase, putative 0.0039 0.0136 0.028
Entamoeba histolytica hypothetical protein 0.0036 0.0119 0.2681
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0031 0.0073
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0014 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0084 0.0441 0.0441
Mycobacterium leprae Probable lipase LipE 0.0071 0.0355 0.0814
Leishmania major glycerol uptake protein, putative 0.0084 0.0441 0.3793
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0098 0.0168
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0084 0.0441 0.0441
Brugia malayi PHD-finger family protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0091 0.0488 0.0488
Onchocerca volvulus 0.0081 0.0422 0.0848
Loa Loa (eye worm) MBOAT family protein 0.0084 0.0441 0.0441
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.013 0.1112
Loa Loa (eye worm) hypothetical protein 0.0511 0.3307 0.3307
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0084 0.0441 0.0688
Brugia malayi Ets-domain containing protein 0.0084 0.0438 0.0438
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0124 0.0124
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0104 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0272 0.0562
Onchocerca volvulus 0.0071 0.0355 0.0709
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0119 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Schistosoma mansoni zinc finger protein 0.0028 0.0064 0.01
Echinococcus granulosus lamin 0.0026 0.0053 0.0053
Brugia malayi hypothetical protein 0.0511 0.3307 0.3307
Giardia lamblia NADH oxidase lateral transfer candidate 0.0066 0.0322 0.7974
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0616 0.4013 0.8325
Brugia malayi intermediate filament protein 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0114 0.0644 0.0644
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0084 0.0441 0.0441
Schistosoma mansoni chromobox protein 0.008 0.0417 0.065
Loa Loa (eye worm) hypothetical protein 0.0231 0.1425 0.1425
Leishmania major glycerol uptake protein, putative 0.0084 0.0441 0.3793
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0124 0.1053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0512 0.0799
Loa Loa (eye worm) hypothetical protein 0.0084 0.0441 0.0441
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0031 0.0253
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0436 0.2803 0.6985
Brugia malayi CHD4 protein 0.0021 0.0016 0.0016
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0124 0.0253
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0078 0.0404 0.063
Echinococcus granulosus expressed protein 0.0039 0.0136 0.0136
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0014 0.0031
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0084 0.0441 0.0688
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0038 0.013 0.1112
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.001 0.0015
Mycobacterium tuberculosis Conserved protein 0.0071 0.0355 0.0881
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0106
Brugia malayi Heterochromatin protein 1 0.008 0.0417 0.0417
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0485 0.313 0.7799
Trypanosoma brucei trypanothione reductase 0.0191 0.116 1
Echinococcus granulosus neuropeptide receptor A26 0.0915 0.6019 0.6019
Treponema pallidum NADH oxidase 0.0066 0.0322 0.7297
Schistosoma mansoni bromodomain containing protein 0.0078 0.0403 0.0628
Mycobacterium ulcerans hypothetical protein 0.0616 0.4013 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0066 0.0322 0.08
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0088 0.0466 0.1092
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0053 0.0053
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0355 0.0881
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0053 0.0053
Plasmodium falciparum thioredoxin reductase 0.0066 0.0322 0.2768
Brugia malayi Fli-1 protein 0.0254 0.158 0.158
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0355 0.0553
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0436 0.2803 0.6985
Schistosoma mansoni hypothetical protein 0.0047 0.0193 0.0301
Trypanosoma cruzi GUP1, putative 0.0084 0.0441 0.3793
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0272 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0088 0.0466 0.0726
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Echinococcus granulosus sterol O acyltransferase 1 0.0084 0.0441 0.0441
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0084 0.0441 0.0688
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0203 0.0418
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0066 0.0322 0.2768
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0071 0.0355 0.0355
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0014 0.0014
Trichomonas vaginalis set domain proteins, putative 0.0737 0.482 1
Brugia malayi Doublecortin family protein 0.002 0.0014 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0272 0.0562
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0272 0.2337
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0088 0.0466 0.1157
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0088 0.0466 0.0466
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0476 0.0476
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0264 0.0264
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.1425 0.1425
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0272 0.2337
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0404 0.0835
Onchocerca volvulus 0.0047 0.0193 0.0373
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0084 0.0441 0.0688
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0264 0.0264
Brugia malayi MBOAT family protein 0.0084 0.0441 0.0441
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0084 0.0441 0.0441
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0014 0.0026
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0014 0.0014
Schistosoma mansoni intermediate filament proteins 0.0026 0.0053 0.0083
Brugia malayi MBOAT family protein 0.0084 0.0441 0.0441
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.026 0.026
Trichomonas vaginalis transmembrane protein nessy, putative 0.0084 0.0441 0.0912
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.018 0.0371
Leishmania major glycerol uptake protein, putative 0.0084 0.0441 0.3793
Echinococcus multilocularis ubiquitin specific protease 41 0.0078 0.0404 0.0404
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0014 0.0106
Loa Loa (eye worm) hypothetical protein 0.0084 0.0441 0.0441
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0191 0.116 0.2889
Echinococcus granulosus dnaJ subfamily B 0.0849 0.5573 0.5573
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0203 0.0393
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0014 0.011
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0104 0.088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0486 0.0486
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0084 0.0441 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.001 0.0015
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0974 0.6414 0.6414
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0104 0.0214
Schistosoma mansoni loxhd1 0.002 0.0014 0.0022
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0052 0.0052
Echinococcus granulosus GA binding protein alpha chain 0.0084 0.0438 0.0438
Leishmania major trypanothione reductase 0.0191 0.116 1
Onchocerca volvulus 0.0737 0.482 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0053
Onchocerca volvulus 0.0071 0.0355 0.0709
Brugia malayi hypothetical protein 0.0231 0.1425 0.1425
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0322 0.2768
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0098 0.024
Loa Loa (eye worm) hypothetical protein 0.0349 0.2217 0.2217
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0002 0.0002
Plasmodium falciparum glutathione reductase 0.0066 0.0322 0.2768
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0272 0.0272
Echinococcus multilocularis dna polymerase eta 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0104 0.0214
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0066 0.0322 0.08
Mycobacterium tuberculosis Probable aminotransferase 0.0616 0.4013 1
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0014 0.0014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0436 0.2803 0.6985
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0264 0.0264
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0114 0.0644 0.0644
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0031 0.0087 0.0087
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.026 0.026
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0078 0.0404 0.915
Trypanosoma brucei unspecified product 0.002 0.0014 0.0106
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1419 0.9399 0.9399
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0022
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0014 0.0014
Schistosoma mansoni inositol monophosphatase 0.0037 0.0124 0.0193
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0355 0.0733
Trypanosoma cruzi glycerol uptake protein, putative 0.0084 0.0441 0.3793
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0084 0.0441 0.0441
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0088 0.0466 0.1157
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0031 0.0253
Trypanosoma cruzi GUP1, putative 0.0084 0.0441 0.3793
Schistosoma mansoni sterol O-acyltransferase 1 0.0084 0.0441 0.0688
Brugia malayi Ets-domain containing protein 0.0084 0.0438 0.0438
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0124 0.1053
Brugia malayi MBOAT family protein 0.0974 0.6414 0.6414
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0014 0.0014
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0404 0.3471
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0104 0.0214
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0044 0.0365
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0272 0.0272
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0031 0.0253
Toxoplasma gondii peptidylprolyl isomerase 0.0038 0.013 0.1112
Schistosoma mansoni hypothetical protein 0.0084 0.0441 0.0688
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0104 0.088
Echinococcus granulosus neuropeptide s receptor 0.0915 0.6019 0.6019
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0088 0.0466 0.1092
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0084 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0045 0.018 0.018
Echinococcus multilocularis RUN 0.002 0.0014 0.0014
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0486 0.0486
Toxoplasma gondii hypothetical protein 0.0084 0.0441 0.3793
Trypanosoma cruzi trypanothione reductase, putative 0.0066 0.0322 0.2768
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0052 0.0052
Schistosoma mansoni rab6-interacting 0.002 0.0014 0.0022
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0355 0.0733
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0031 0.0073
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0084 0.0441 0.0688
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0015 0.0015
Loa Loa (eye worm) runx1 0.0064 0.0308 0.0308
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0066 0.0322 0.2768
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0201 0.0201
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0014 0.0014
Loa Loa (eye worm) glutathione reductase 0.0191 0.116 0.116
Echinococcus multilocularis lamin dm0 0.0026 0.0053 0.0053
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0014 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0114 0.0644 0.1005
Echinococcus multilocularis neuropeptide receptor A26 0.0915 0.6019 0.6019
Echinococcus granulosus microtubule associated protein 2 0.0796 0.522 0.522
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0021 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0014 0.0014
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0355 0.0355
Giardia lamblia PHD finger protein 15 0.0034 0.0104 0.2537
Loa Loa (eye worm) hypothetical protein 0.1509 1 1
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0616 0.4013 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0066 0.0322 0.2768
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0441 0.0912
Leishmania major hypothetical protein, conserved 0.0025 0.0044 0.0365
Echinococcus granulosus lamin dm0 0.0026 0.0053 0.0053
Toxoplasma gondii NADPH-glutathione reductase 0.0066 0.0322 0.2768
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0485 0.313 0.7799
Schistosoma mansoni hypothetical protein 0.0036 0.0119 0.0186
Loa Loa (eye worm) hypothetical protein 0.0035 0.0115 0.0115
Echinococcus granulosus peregrin 0.0036 0.0122 0.0122
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0066 0.0322 0.2768
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0092 0.0188
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0066 0.0322 0.0322
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0272 0.0562
Trichomonas vaginalis rotamase, putative 0.0038 0.013 0.0267
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0014 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0014 0.0106
Echinococcus granulosus cpg binding protein 0.0098 0.0538 0.0538
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0066 0.0322 0.0322
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0031 0.0087 0.0136
Schistosoma mansoni hypothetical protein 0.0024 0.0038 0.0059
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0104 0.0161
Schistosoma mansoni cpg binding protein 0.0091 0.0488 0.0761
Brugia malayi hypothetical protein 0.0036 0.0119 0.0119
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0355 0.3048
Echinococcus multilocularis cpg binding protein 0.0098 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.003 0.006
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0084 0.0441 0.0441
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0974 0.6414 0.6414
Schistosoma mansoni lipoxygenase 0.0057 0.026 0.0405
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0272 0.2337
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0084 0.0438 0.0438
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0322 0.2768
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0616 0.4013 1
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0355 0.0733
Echinococcus multilocularis microtubule associated protein 2 0.0796 0.522 0.522
Trypanosoma cruzi trypanothione reductase, putative 0.0191 0.116 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.009 0.009
Entamoeba histolytica hypothetical protein 0.0036 0.0119 0.2681
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0104 0.0214
Schistosoma mansoni hypothetical protein 0.0039 0.0142 0.0221
Loa Loa (eye worm) hhat protein 0.0084 0.0441 0.0441
Onchocerca volvulus 0.0084 0.0441 0.0888
Echinococcus multilocularis zinc finger protein 0.089 0.5851 0.5851
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0104 0.0214
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0084 0.0441 0.3793
Echinococcus multilocularis geminin 0.0196 0.119 0.119
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0078 0.0404 0.063
Plasmodium falciparum ornithine aminotransferase 0.0088 0.0466 0.4006
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0322 0.691
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0375 0.0375
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0084 0.0441 0.0441
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0114 0.0644 0.1005
Loa Loa (eye worm) hypothetical protein 0.0071 0.0357 0.0357
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0422 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0092 0.0188
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0322 0.691
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0404 0.3471
Loa Loa (eye worm) hypothetical protein 0.0058 0.0265 0.0265
Trypanosoma cruzi glycerol uptake protein, putative 0.0084 0.0441 0.3793
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.1425 0.1425
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0066 0.0322 0.6702
Echinococcus granulosus chromobox protein 1 0.008 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0034 0.0104 0.0104
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0066 0.0322 0.2768
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.009 0.009
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0014 0.0014
Schistosoma mansoni zinc finger protein 0.0974 0.6414 1
Toxoplasma gondii thioredoxin reductase 0.0191 0.116 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Schistosoma mansoni ets-related 0.0254 0.158 0.2463
Echinococcus granulosus RUN 0.002 0.0014 0.0014
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0014 0.011
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0088 0.0466 0.4006
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.003
Trichomonas vaginalis porcupine, putative 0.0084 0.0441 0.0912
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0106
Schistosoma mansoni ap endonuclease 0.0018 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0071 0.0355 0.0881
Echinococcus multilocularis dnaJ subfamily B 0.0849 0.5573 0.5573
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0106
Echinococcus granulosus thioredoxin glutathione reductase 0.0191 0.116 0.116
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0485 0.313 0.7783
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0049 0.0204 0.0204
Schistosoma mansoni polycystin 1-related 0.002 0.0014 0.0022

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.