Detailed information for compound 549159

Basic information

Technical information
  • TDR Targets ID: 549159
  • Name: (3-methoxy-3-oxo-propyl)-trimethyl-ammonium i odide
  • MW: 273.112 | Formula: C7H16INO2
  • H donors: 0 H acceptors: 1 LogP: 0.96 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)CC[N+](C)(C)C.[I-]
  • InChi: 1S/C7H16NO2.HI/c1-8(2,3)6-5-7(9)10-4;/h5-6H2,1-4H3;1H/q+1;/p-1
  • InChiKey: OQPJXBMHIDDMPB-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • (3-methoxy-3-oxopropyl)-trimethylammonium iodide
  • (3-methoxy-3-oxo-propyl)-trimethyl-azanium iodide
  • (3-keto-3-methoxy-propyl)-trimethyl-ammonium iodide
  • (3-methoxy-3-oxopropyl)-trimethylazanium iodide
  • 19075-27-5
  • PK 685
  • 1-Propanaminium, 3-methoxy-N,N,N-trimethyl-3-oxo-, iodide (9CI)
  • AMMONIUM, (2-CARBOXYETHYL)TRIMETHYL-, IODIDE, METHYL ESTER

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0048 0.0535
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0238 0.0818 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0207 0.1292
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0075 0.0073
Echinococcus multilocularis musashi 0.0029 0.0057 0.0054
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0086 0.0974
Toxoplasma gondii ABC1 family protein 0.007 0.0207 0.2505
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0048 0.0535
Trypanosoma brucei glucosidase, putative 0.0037 0.0086 0.1048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Echinococcus granulosus lamin 0.0029 0.0057 0.0054
Echinococcus granulosus o acyltransferase membrane bound domain 0.0238 0.0818 0.0816
Brugia malayi Pre-SET motif family protein 0.022 0.0753 0.0751
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.0793 0.079
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0136 0.1643
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0231 0.0793 0.0791
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0238 0.0818 0.0816
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0003 0.0017
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0022 0.0031 0.0543
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0093 0.2179
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0028 0.0026
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0022 0.002
Schistosoma mansoni hypothetical protein 0.1246 0.4486 0.4484
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0095 0.0094
Brugia malayi MBOAT family protein 0.0238 0.0818 0.0816
Echinococcus granulosus dnaJ subfamily B 0.1246 0.4486 0.4484
Brugia malayi intermediate filament protein 0.0029 0.0057 0.0055
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0022 0.036
Schistosoma mansoni hypothetical protein 0.0014 0.0003 0.0001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0048 0.0535
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.0207
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.2762 1 1
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0207 0.2388
Trypanosoma cruzi GUP1, putative 0.0238 0.0818 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0022 0.0115
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0476 0.0474
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0022 0.0031 0.0553
Schistosoma mansoni hypothetical protein 0.0039 0.0095 0.0093
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0554 0.0552
Brugia malayi ecdysteroid receptor 0.0021 0.0028 0.0026
Mycobacterium tuberculosis Conserved protein 0.007 0.0207 0.1292
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0404 0.0401
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0075 0.0225 1
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0087 0.0086
Entamoeba histolytica hypothetical protein 0.0238 0.0818 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0095 0.0935
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0207 0.2518
Trypanosoma cruzi glycerol uptake protein, putative 0.0238 0.0818 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.002 0.0018
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0111 0.0356 0.4342
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0136 0.1642
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0093 0.1119
Onchocerca volvulus 0.0029 0.0057 0.0635
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0086 0.0974
Schistosoma mansoni cpg binding protein 0.0123 0.0399 0.0397
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.002 0.0223
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0246
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.0793 0.0791
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0216 0.0213
Loa Loa (eye worm) hypothetical protein 0.0111 0.0356 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0019
Leishmania major DNA polymerase kappa, putative 0.0019 0.0022 0.024
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0448 0.1583 1
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.0018
Plasmodium vivax ornithine aminotransferase, putative 0.0022 0.0031 0.014
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0022 0.024
Trichomonas vaginalis helicase, putative 0.0026 0.0048 0.0535
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0111 0.0356 1
Echinococcus multilocularis zinc finger protein 0.2524 0.9134 0.9134
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0075 0.0072
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0028 0.0026
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0356 0.4355
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0075 0.0225 0.2724
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0238 0.0818 0.0816
Brugia malayi Pre-SET motif family protein 0.0034 0.0075 0.0073
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0075 0.0225 0.2737
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.0793 0.0791
Brugia malayi MBOAT family protein 0.0238 0.0818 0.0816
Schistosoma mansoni intermediate filament proteins 0.0029 0.0057 0.0055
Plasmodium vivax hypothetical protein, conserved 0.007 0.0207 0.2347
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0028 0.0026
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0035 0.0405
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0028 0.0026
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0225 0.2754
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0129 0.0127
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0137 0.1669
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0136 0.1452
Trichomonas vaginalis esterase, putative 0.007 0.0207 0.2388
Onchocerca volvulus 0.0039 0.0095 0.1078
Schistosoma mansoni hypothetical protein 0.0072 0.0216 0.0214
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0035 0.0627
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0028 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0974
Trypanosoma cruzi glycerol uptake protein, putative 0.0238 0.0818 1
Mycobacterium ulcerans beta-lactamase 0.007 0.0207 0.4039
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0028 0.0026
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0137 0.1635
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0095 0.0092
Onchocerca volvulus Huntingtin homolog 0.0119 0.0384 0.4436
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0031 0.0553
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0106 0.0104
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0404 0.4917
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.0207
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0003 0.0017
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0022 0.002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0028 0.0026
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0238 0.0818 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0554 0.0552
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0022 0.0115
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0137 0.0134
Echinococcus multilocularis lamin 0.0029 0.0057 0.0054
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.024
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0028 0.0026
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0031 0.0553
Leishmania major glycerol uptake protein, putative 0.0238 0.0818 1
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0035 0.0034
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0803 0.0801
Trichomonas vaginalis conserved hypothetical protein 0.0238 0.0818 0.9483
Onchocerca volvulus 0.0021 0.0028 0.0307
Loa Loa (eye worm) acetyltransferase 0.0144 0.0476 0.0475
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0111 0.0356 0.0354
Brugia malayi steroid hormone receptor 0.0021 0.0028 0.0026
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0031 0.0029
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0003 0.0041
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0153 0.0509 0.3199
Echinococcus granulosus cpg binding protein 0.0123 0.0399 0.0396
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0028 0.0026
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0022 0.0019
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0137 0.165
Plasmodium falciparum ornithine aminotransferase 0.0022 0.0031 0.0358
Onchocerca volvulus 0.0039 0.0095 0.1078
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0263
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0136 0.1629
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0086 0.0083
Echinococcus multilocularis muscleblind protein 0.0909 0.326 0.3258
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0137 0.1564
Schistosoma mansoni lipoxygenase 0.0102 0.0321 0.0319
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0207 0.0205
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0095 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0111 0.0356 0.4117
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0086 0.0083
Entamoeba histolytica vacuolar protein sorting 26 0.0238 0.0818 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.024
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0476 0.0474
Leishmania major hypothetical protein, conserved 0.0238 0.0818 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0106 0.1212
Brugia malayi MBOAT family protein 0.0238 0.0818 0.0816
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0128
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0086 0.0085
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0057 0.0055
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0022 0.024
Trichomonas vaginalis hypothetical protein 0.0014 0.0004 0.0019
Loa Loa (eye worm) inositol-1 0.0075 0.0225 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.0018
Echinococcus granulosus o acyltransferase membrane bound domain 0.0238 0.0818 0.0816
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0003 0.0017
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0404 0.0402
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0028 0.0307
Echinococcus granulosus intermediate filament protein 0.0029 0.0057 0.0054
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0031 0.0553
Brugia malayi MH2 domain containing protein 0.0121 0.0393 0.0391
Echinococcus multilocularis 0.0014 0.0003 0.0001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0022 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0028 0.0026
Leishmania major cytochrome p450-like protein 0.0014 0.0003 0.0017
Schistosoma mansoni cpg binding protein 0.0116 0.0375 0.0373
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0263
Schistosoma mansoni sterol O-acyltransferase 1 0.0238 0.0818 0.0816
Brugia malayi CXXC zinc finger family protein 0.0116 0.0375 0.0373
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0028 0.0026
Echinococcus multilocularis dna polymerase eta 0.0019 0.0022 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0404 0.7928
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0461 0.0459
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0137 0.1564
Trypanosoma brucei unspecified product 0.0019 0.0022 0.0263
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0111 0.0356 0.4342
Loa Loa (eye worm) hypothetical protein 0.0909 0.326 0.3259
Loa Loa (eye worm) MBOAT family protein 0.0238 0.0818 0.0817
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0111 0.0356 0.0354
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0028 0.0026
Onchocerca volvulus 0.0029 0.0057 0.0635
Toxoplasma gondii exonuclease III APE 0.0019 0.002 0.0206
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0028 0.0026
Echinococcus multilocularis tumor protein p63 0.0331 0.1158 0.1155
Schistosoma mansoni rab6-interacting 0.0039 0.0095 0.0093
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0106 0.1079
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0008 0.0007
Brugia malayi Cytochrome P450 family protein 0.0023 0.0035 0.0033
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0476 0.0474
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0207 0.1292
Onchocerca volvulus 0.0049 0.0129 0.1472
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0031 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0356 0.4117
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0106 0.1263
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0207 0.1292
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0086 0.0974
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.0207
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0086 0.0084
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0238 0.0818 0.0816
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0404 0.7928
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0238 0.0818 0.0816
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0404 0.2536
Schistosoma mansoni coup transcription factor 0.0021 0.0028 0.0026
Brugia malayi hypothetical protein 0.0072 0.0216 0.0214
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0137 0.165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Brugia malayi Inositol-1 0.0075 0.0225 0.0223
Echinococcus multilocularis inositol monophosphatase 1 0.0075 0.0225 0.0223
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0075 0.0073
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0028 0.0026
Schistosoma mansoni inositol monophosphatase 0.0075 0.0225 0.0223
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0028 0.0307
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0111 0.0356 0.0354
Loa Loa (eye worm) hhat protein 0.0238 0.0818 0.0817
Brugia malayi Cytochrome P450 family protein 0.0023 0.0035 0.0033
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0238 0.0818 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.0753 0.0753
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0075 0.0225 0.4393
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0404 0.4926
Onchocerca volvulus 0.025 0.0863 1
Echinococcus granulosus muscleblind protein 0.0909 0.326 0.3258
Giardia lamblia DINP protein human, muc B family 0.0019 0.0022 0.0041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0017 0.0015
Mycobacterium leprae conserved hypothetical protein 0.007 0.0207 0.4039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0057 0.0056
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0022 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0075 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0028 0.0026
Brugia malayi hypothetical protein 0.0033 0.0071 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0095 0.0092
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0207 0.0205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.0793 0.079
Onchocerca volvulus 0.007 0.0207 0.2388
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0238 0.0818 0.0816
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0238 0.0818 0.0816
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0031 0.0343
Brugia malayi hypothetical protein 0.0039 0.0095 0.0093
Schistosoma mansoni lipoxygenase 0.0172 0.0578 0.0576
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0554 0.0552
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.002 0.0212
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0238 0.0818 0.0817
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0028 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0075 0.0072
Onchocerca volvulus 0.0116 0.0375 0.4333
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0153 0.0509 0.5888
Schistosoma mansoni lamin 0.0029 0.0057 0.0055
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0136 0.1643
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0803 0.0802
Echinococcus multilocularis neuropeptide s receptor 0.0478 0.1691 0.1689
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0028 0.0026
Brugia malayi Doublecortin family protein 0.0039 0.0095 0.0093
Onchocerca volvulus 0.007 0.0207 0.2388
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0086 0.1027
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.0207
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0404 0.7928
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0003 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0393 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0238 0.0818 0.9483
Onchocerca volvulus Huntingtin homolog 0.0119 0.0384 0.4436
Toxoplasma gondii hypothetical protein 0.0238 0.0818 1
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0031 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0974
Echinococcus granulosus dna polymerase kappa 0.0019 0.0022 0.0019
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0087 0.0085
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.002 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0028 0.0028
Brugia malayi nuclear receptor NHR-88 0.0021 0.0028 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.0793 0.0791
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.0793 0.079
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.002 0.0106
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0022 0.002
Trypanosoma cruzi GUP1, putative 0.0238 0.0818 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.0793 0.079
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0238 0.0818 1
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0095 0.0094
Entamoeba histolytica hypothetical protein 0.0072 0.0216 0.2619
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0061 0.0059
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0207 0.4039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0035 0.0032
Leishmania major hypothetical protein, conserved 0.007 0.0207 0.2518
Brugia malayi Hhat protein 0.0238 0.0818 0.0816
Echinococcus multilocularis sterol O acyltransferase 1 0.0238 0.0818 0.0816
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0238 0.0818 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0061 0.0059
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0974
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.0054
Echinococcus multilocularis neuropeptide receptor A26 0.0478 0.1691 0.1689
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0028 0.0026
Brugia malayi hypothetical protein 0.0039 0.0095 0.0093
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0067 0.0197 0.3826
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0048 0.0535
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0028 0.0026
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0207 0.1292
Leishmania major cytochrome p450-like protein 0.0014 0.0003 0.0017
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0225 0.2595
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0031 0.0553
Leishmania major glycerol uptake protein, putative 0.0238 0.0818 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0106 0.1263
Schistosoma mansoni hypothetical protein 0.0238 0.0818 0.0816
Echinococcus granulosus RUN 0.0039 0.0095 0.0092
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0172 0.0578 0.0576
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.0383
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0075 0.0073
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0207 0.0205
Schistosoma mansoni alpha glucosidase 0.0037 0.0086 0.0084
Loa Loa (eye worm) CXXC zinc finger family protein 0.0116 0.0375 0.0374
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0238 0.0818 0.0816
Loa Loa (eye worm) hypothetical protein 0.0238 0.0818 0.0817
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0238 0.0818 0.0816
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0028 0.0026
Brugia malayi MAP kinase sur-1 0.0051 0.0137 0.0135
Loa Loa (eye worm) hypothetical protein 0.0909 0.326 0.3259
Trypanosoma brucei glycerol uptake protein, putative 0.0238 0.0818 1
Mycobacterium ulcerans hypothetical protein 0.007 0.0207 0.4039
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.0207
Echinococcus granulosus tumor protein p63 0.0331 0.1158 0.1155
Schistosoma mansoni loxhd1 0.0039 0.0095 0.0093
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0093 0.1121
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0137 0.0136
Echinococcus granulosus o acyltransferase membrane bound domain 0.0238 0.0818 0.0816
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0086 0.1027
Echinococcus granulosus Aminotransferase class III 0.0022 0.0031 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Trichomonas vaginalis inositol monophosphatase, putative 0.0075 0.0225 0.2595
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0207 0.2388
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0136 0.1642
Echinococcus multilocularis ubiquitin specific protease 41 0.0111 0.0356 0.0354
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0238 0.0818 0.0816
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0207 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Trichomonas vaginalis porcupine, putative 0.0238 0.0818 0.9483
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0238 0.0818 0.0816
Brugia malayi hypothetical protein 0.0051 0.0136 0.0134
Mycobacterium leprae Probable lipase LipE 0.007 0.0207 0.4039
Leishmania major glycerol uptake protein, putative 0.0238 0.0818 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0061 0.0059
Leishmania major glycerol uptake protein, putative 0.0238 0.0818 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0137 0.165
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0031 0.0553
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0086 0.1027
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0238 0.0818 0.0816
Leishmania major hypothetical protein, conserved 0.0051 0.0136 0.1643
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0028 0.0026
Echinococcus granulosus dna polymerase eta 0.0019 0.0022 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.0207
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0035 0.0032
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0207 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0021
Schistosoma mansoni rab6-interacting 0.0039 0.0095 0.0093
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0028 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0028 0.0026
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0061 0.0059
Mycobacterium tuberculosis Conserved protein 0.007 0.0207 0.1292
Mycobacterium ulcerans lipase LipD 0.007 0.0207 0.4039
Echinococcus granulosus sterol O acyltransferase 1 0.0238 0.0818 0.0816
Treponema pallidum alginate O-acetylation protein (algI) 0.0238 0.0818 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0172 0.0578 0.0576
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0028 0.0028
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.2762 1 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0003 0.0017
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0137 0.165
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0207 0.2388
Trypanosoma cruzi glycerol uptake protein, putative 0.0238 0.0818 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0111 0.0356 0.0354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0028 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0478 0.1691 0.1689
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0022 0.024
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0028 0.0026
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0085 0.0084
Echinococcus multilocularis lamin dm0 0.0029 0.0057 0.0054
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0031 0.0029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0216 0.0213
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0022 0.0031 0.0553
Schistosoma mansoni alpha-glucosidase 0.0142 0.047 0.0468
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0785 0.2808 0.2806
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0048 0.0535
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0057 0.0056
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0238 0.0818 0.0816
Entamoeba histolytica hypothetical protein 0.0014 0.0002 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0022 0.036
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0207 0.2518
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0974
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0238 0.0818 1
Onchocerca volvulus 0.007 0.0207 0.2388
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0238 0.0818 0.0816
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0111 0.0356 0.0354
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0393 0.0393
Brugia malayi MBOAT family protein 0.0238 0.0818 0.0816
Brugia malayi cytochrome P450 0.0014 0.0003 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0035 0.0405
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0028 0.0026
Loa Loa (eye worm) cytochrome P450 0.0014 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0238 0.0818 0.0816
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0067 0.0197 0.1224
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0111 0.0356 0.0354
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.002 0.0018
Entamoeba histolytica hypothetical protein 0.0072 0.0216 0.2619
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0095 0.0094
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0095 0.0092
Entamoeba histolytica hypothetical protein 0.0072 0.0216 0.2619
Echinococcus granulosus ubiquitin specific protease 41 0.0111 0.0356 0.0354
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0086 0.1027
Entamoeba histolytica hypothetical protein 0.0072 0.0216 0.2619
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.002 0.0212
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.002 0.0222
Brugia malayi beta-lactamase family protein 0.007 0.0207 0.0206
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0141 0.0141
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0248 0.0853 0.0851
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0238 0.0818 0.0816
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0106 0.1212
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0075 0.0072
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0404 0.0401
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0207 0.2536
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.002 0.0333
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0238 0.0818 1
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0022 0.0263
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0028 0.0026
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0028 0.0026
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0137 0.3464
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0028 0.0026
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0404 0.0402
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0028 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0238 0.0818 0.9483
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0238 0.0818 0.0817
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Brugia malayi Cytochrome P450 family protein 0.0014 0.0003 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0207 0.2388
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0031 0.0029
Loa Loa (eye worm) beta-lactamase 0.007 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0238 0.0818 0.0817
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0231 0.0793 0.0792
Echinococcus granulosus neuropeptide receptor A26 0.0478 0.1691 0.1689
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0031 0.0029
Brugia malayi hypothetical protein 0.0119 0.0384 0.0382
Echinococcus multilocularis dnaJ subfamily B 0.1246 0.4486 0.4484
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0535
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0035 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Schistosoma mansoni cytochrome P450 0.0014 0.0003 0.0001
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0238 0.0818 0.0816
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0028 0.0028
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0225 0.2737
Plasmodium vivax SET domain protein, putative 0.0034 0.0075 0.0687
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0022 0.0228
Brugia malayi nuclear hormone receptor 0.0021 0.0028 0.0026
Mycobacterium tuberculosis Probable aminotransferase 0.0153 0.0509 0.3199
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0356 0.4342
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0225 0.2737
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0356 0.4342
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0031 0.0553
Echinococcus multilocularis muscleblind protein 1 0.0909 0.326 0.3258
Mycobacterium tuberculosis Conserved protein 0.007 0.0207 0.1292
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0137 0.165
Schistosoma mansoni hypothetical protein 0.0023 0.0035 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0048 0.0535
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0095 0.0092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0207 0.1292
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0111 0.0356 0.4117
Loa Loa (eye worm) hypothetical protein 0.0238 0.0818 0.0817
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0207 0.2388
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0057 0.0056
Schistosoma mansoni cpg binding protein 0.0123 0.0399 0.0397
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0028 0.0028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0223
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0207 0.4039
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0028 0.0026
Echinococcus granulosus inositol monophosphatase 1 0.0075 0.0225 0.0223
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0153 0.0509 1
Leishmania major cytochrome p450-like protein 0.0023 0.0035 0.0405
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0028 0.0026
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0137 0.0134
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0137 0.165
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0137 0.0135
Loa Loa (eye worm) MBOAT family protein 0.2762 1 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0086 0.1012
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0028 0.0026
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0002 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0022 0.0019
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0028 0.0026
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0061 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0048 0.0535
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0554 0.0552
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0031 0.0177
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0022 0.0021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0028 0.0026
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0136 0.1663
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0028 0.0026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0137 0.0134
Echinococcus granulosus lamin dm0 0.0029 0.0057 0.0054
Onchocerca volvulus 0.0096 0.03 0.3467
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0028 0.0026
Brugia malayi diacylglycerol acyltransferase 0.0238 0.0818 0.0816
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0095 0.1136
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0028 0.0026
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0022 0.0031 0.0553
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0051 0.0136 0.0135
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0028 0.0026
Brugia malayi beta-lactamase 0.007 0.0207 0.0206
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0216 0.0214
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0028 0.0026
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0086 0.1027
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.0383
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0008 0.0006
Trichomonas vaginalis set domain proteins, putative 0.025 0.0863 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0028 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0048 0.0535
Brugia malayi Muscleblind-like protein 0.0909 0.326 0.3258
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0028 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Schistosoma mansoni lamin 0.0029 0.0057 0.0055
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0087 0.0085
Echinococcus multilocularis cpg binding protein 0.0123 0.0399 0.0396
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Leishmania major DNA polymerase eta, putative 0.0019 0.0022 0.024
Brugia malayi beta-lactamase family protein 0.007 0.0207 0.0206
Loa Loa (eye worm) hypothetical protein 0.0034 0.0075 0.0074
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0095 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0111 0.0356 0.0354
Trichomonas vaginalis transmembrane protein nessy, putative 0.0238 0.0818 0.9483
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0035 0.0034
Onchocerca volvulus 0.0238 0.0818 0.9483
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0238 0.0818 0.0816
Schistosoma mansoni inositol monophosphatase 0.0075 0.0225 0.0223
Schistosoma mansoni polycystin 1-related 0.0039 0.0095 0.0093
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0035 0.0428
Echinococcus multilocularis RUN 0.0039 0.0095 0.0092
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0075 0.0879
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0086 0.0974
Loa Loa (eye worm) MBOAT family protein 0.0238 0.0818 0.0817
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0263
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.002 0.0223
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0238 0.0818 0.0817
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0062 0.0059
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.002 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0028 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0263
Onchocerca volvulus 0.0034 0.0075 0.0849
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0225 0.2595
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0028 0.0026
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0207 0.1292
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0028 0.0026
Schistosoma mansoni alpha-glucosidase 0.0142 0.047 0.0468
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0031 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0028 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0137 0.1564
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0225 0.2737
Schistosoma mansoni DNA polymerase eta 0.0019 0.0022 0.002
Entamoeba histolytica hypothetical protein, conserved 0.0238 0.0818 1
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0207 0.1292
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Leishmania major glycerol uptake protein, putative 0.0238 0.0818 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0004 0.0019
Trypanosoma brucei protein kinase, putative 0.0051 0.0137 0.1669
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0153 0.0509 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0028 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0974
Trypanosoma brucei glycerol uptake protein, putative 0.0238 0.0818 1
Echinococcus granulosus zinc finger protein 0.2524 0.9134 0.9134
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.077 0.9409
Loa Loa (eye worm) hhat protein 0.0238 0.0818 0.0817
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0022 0.0228
Schistosoma mansoni zinc finger protein 0.2762 1 1
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0031 0.0177
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0137 0.1564
Mycobacterium ulcerans hypothetical protein 0.0153 0.0509 1
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0031 0.5
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0031 0.0029
Brugia malayi Cytochrome P450 family protein 0.0052 0.0141 0.0139

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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