Detailed information for compound 580759

Basic information

Technical information
  • TDR Targets ID: 580759
  • Name: 2-methylbenzene-1,4-diamine hydrochloride
  • MW: 158.629 | Formula: C7H11ClN2
  • H donors: 2 H acceptors: 0 LogP: 1.73 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1ccc(c(c1)C)N.Cl
  • InChi: 1S/C7H10N2.ClH/c1-5-4-6(8)2-3-7(5)9;/h2-4H,8-9H2,1H3;1H
  • InChiKey: HRWVOWXYMGUWLK-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • (4-amino-2-methyl-phenyl)amine hydrochloride
  • 74612-12-7
  • 1,4-Benzenediamine, 2-methyl-, monohydrochloride
  • 2-Methyl-1,4-benzenediamine monohydrochloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0037 0.0216 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Leishmania major cathepsin L-like protease 0.0018 0.0032 0.0053
Onchocerca volvulus 0.0244 0.2307 0.5113
Loa Loa (eye worm) hypothetical protein 0.0048 0.0335 0.0617
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Brugia malayi Cathepsin L-like precursor 0.0018 0.0032 0.0027
Mycobacterium tuberculosis Conserved protein 0.0028 0.0134 0.0712
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0074 0.0598 0.0572
Giardia lamblia Sugar-proton symporter 0.0033 0.0184 0.1001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0834 0.1588
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.2869 0.5547
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0047 0.0103
Echinococcus multilocularis solute carrier family 22 0.0033 0.0184 0.019
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0056 0.0135
Schistosoma mansoni apoferritin-2 0.0019 0.0038 0.0051
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Brugia malayi hypothetical protein 0.0527 0.5157 1
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.2558 1
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0461 0.1484
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2997
Brugia malayi excitatory GABA receptor EXP-1A 0.0037 0.0216 0.0386
Toxoplasma gondii lysine-tRNA ligase 0.0053 0.0381 0.0576
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.1031 0.6733
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0128 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Echinococcus granulosus lysyl tRNA synthetase 0.0053 0.0381 0.0491
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0071 0.0564 0.0626
Schistosoma mansoni glucose transport protein 0.0237 0.2235 0.3013
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0115 0.1011 0.1933
Leishmania major hypothetical protein, conserved 0.0054 0.0396 0.1268
Brugia malayi Probable ClpP-like protease 0.0167 0.1526 0.2936
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Schistosoma mansoni alpha glucosidase 0.0075 0.06 0.0808
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Onchocerca volvulus 0.002 0.0046 0.0064
Trypanosoma brucei glucosidase, putative 0.0075 0.06 0.1946
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.1518 0.1495
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Schistosoma mansoni caspase-3 (C14 family) 0.0159 0.1448 0.1952
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0183 0.0322
Loa Loa (eye worm) hypothetical protein 0.0071 0.0564 0.1063
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0923 0.1244
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0019 0.0038 0.007
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.2558 1
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0037 0.0216 0.0227
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0131 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0598 0.0806
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0074 0.0598 0.0572
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0396 0.1268
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0053 0.0381 0.2302
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0037 0.0216 0.0227
Schistosoma mansoni hypothetical protein 0.0176 0.1626 0.2192
Leishmania major glucose transporter, lmgt3 0.0073 0.0588 0.1908
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0184 0.0616
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0183 0.0189
Echinococcus multilocularis cpg binding protein 0.0037 0.0223 0.0235
Toxoplasma gondii sugar transporter ST2 0.0033 0.0184 0.0278
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0541 0.0599
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0172 0.1585 0.523
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0314 0.3017 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0128 0.0396
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Leishmania major mitochondrial DNA polymerase beta 0.0314 0.3017 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0062 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0109 0.0948 0.6114
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.06 0.0786
Schistosoma mansoni caspase-7 (C14 family) 0.0212 0.1986 0.2677
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0046 0.0102
Plasmodium falciparum calcium-dependent protein kinase 3 0.0074 0.0598 0.0572
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.06 0.2261
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.2558 1
Mycobacterium ulcerans bacterioferritin BfrB 0.0019 0.0038 0.007
Schistosoma mansoni ferritin 0.0019 0.0038 0.0051
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Schistosoma mansoni ferritin 0.0019 0.0038 0.0051
Brugia malayi MAP kinase sur-1 0.0172 0.1585 0.305
Plasmodium vivax vivapain-2 0.0018 0.0032 0.0004
Schistosoma mansoni glucose transport protein 0.0237 0.2235 0.3013
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0522 0.0578
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0043 0.0062
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0172 0.1585 0.305
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0062 0.0086
Schistosoma mansoni lysyl-tRNA synthetase 0.0053 0.0381 0.0513
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0043 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.06 0.2261
Trypanosoma brucei sugar transporter, putative 0.0033 0.0184 0.0559
Schistosoma mansoni hypothetical protein 0.03 0.2869 0.3867
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0062 0.005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0541 0.3424
Brugia malayi follicle stimulating hormone receptor 0.0244 0.2304 0.4449
Echinococcus multilocularis peptidase Clp (S14 family) 0.0109 0.0948 0.1066
Schistosoma mansoni hypothetical protein 0.0017 0.0016 0.0021
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0062 0.0083
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0032 0.0027
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0062 0.0083
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Loa Loa (eye worm) hypothetical protein 0.0053 0.0381 0.0706
Onchocerca volvulus 0.0037 0.0216 0.0443
Trypanosoma brucei metacaspase MCA3 0.0083 0.0685 0.223
Loa Loa (eye worm) hypothetical protein 0.016 0.1458 0.2802
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0454 0.1687
Schistosoma mansoni glucose transporter 0.0033 0.0184 0.0247
Echinococcus granulosus zinc finger protein 0.0023 0.0082 0.0086
Schistosoma mansoni kinase 0.0062 0.0469 0.0632
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.06 0.2261
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.1518 1
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.1518 0.5891
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0062 0.0086
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0385 0.3725 0.5633
Echinococcus multilocularis nAChR subunit 0.0037 0.0216 0.0227
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0062 0.006
Leishmania major hypothetical protein, conserved 0.0246 0.233 0.7712
Loa Loa (eye worm) cysteine protease 0.0018 0.0032 0.0027
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0028 0.004
Onchocerca volvulus 0.0033 0.0184 0.037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0396 0.1268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Echinococcus multilocularis geminin 0.0176 0.1626 0.1843
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0541 0.1749
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0043 0.0062
Echinococcus multilocularis solute carrier family 22 0.0033 0.0184 0.019
Plasmodium vivax metacaspase 1, putative 0.0083 0.0685 0.0659
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0033 0.0184 0.0156
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0062 0.006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0665
Echinococcus granulosus cpg binding protein 0.0037 0.0223 0.0277
Brugia malayi RNA, U transporter 1 0.008 0.0653 0.1235
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0043 0.0079
Giardia lamblia Kinase, PLK 0.0115 0.1011 0.6313
Plasmodium falciparum hexose transporter 0.0237 0.2235 0.2214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0834 0.1124
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.06 0.1946
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0908 0.1733
Loa Loa (eye worm) hypothetical protein 0.0166 0.1518 0.2919
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.037 0.0403
Leishmania major importin beta-1 subunit, putative 0.0023 0.0077 0.0205
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Loa Loa (eye worm) major facilitator superfamily transporter 0.0033 0.0184 0.0323
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0396 0.037
Schistosoma mansoni zinc finger protein 0.0017 0.0016 0.0021
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0131 0.1163 0.756
Loa Loa (eye worm) runx1 0.0058 0.0431 0.0804
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2541
Echinococcus granulosus dnaJ subfamily B 0.0474 0.4621 0.622
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0588 0.2216
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0028 0.0134 0.0708
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0685 0.2598
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.1518 0.1495
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0062 0.0083
Leishmania major glucose transporter, lmgt2 0.0073 0.0588 0.1908
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Echinococcus multilocularis solute carrier family 22 0.0033 0.0184 0.019
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.1518 0.9945
Plasmodium vivax importin-beta 2, putative 0.0028 0.0131 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.1585 0.6156
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.06 0.1946
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.1518 0.5006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0336 0.3236 0.6263
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0128 0.0374
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0037 0.0216 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Echinococcus granulosus caspase 0.0159 0.1448 0.1933
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0045 0.03 0.1831
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.3236 0.3688
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Trypanosoma cruzi sugar transporter, putative 0.0033 0.0184 0.0559
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0032 0.0027
Schistosoma mansoni microtubule-associated protein tau 0.0751 0.7418 1
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0032 0.0043
Plasmodium vivax vivapain-2 0.0018 0.0032 0.0004
Schistosoma mansoni alpha-glucosidase 0.0289 0.2764 0.3727
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.037 0.0498
Schistosoma mansoni sugar transporter 0.0033 0.0184 0.0247
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0107 0.0923 0.1223
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.1518 0.9944
Toxoplasma gondii cathepsin CPL 0.0018 0.0032 0.0048
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0293 0.0926
Onchocerca volvulus Putative nachr subunit 0.0037 0.0216 0.0443
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0409 0.0762
Brugia malayi glutathione reductase 0.0051 0.0367 0.0679
Echinococcus granulosus caspase 3 0.0076 0.0611 0.0802
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0032 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0184 0.0616
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Schistosoma mansoni alpha-glucosidase 0.0289 0.2764 0.3727
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Schistosoma mansoni ferritin 0.0019 0.0038 0.0051
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0216 0.0386
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.06 0.2261
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0035 0.0047
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Echinococcus multilocularis dnaJ subfamily B 0.0474 0.4621 0.5275
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0062 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Plasmodium vivax proline--tRNA ligase, putative 0.0083 0.0683 0.0657
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0019 0.0038 0.0071
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0062 0.0086
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0029 0.0142 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0062 0.0086
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0062 0.005
Echinococcus multilocularis General substrate transporter 0.0204 0.19 0.2157
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0032 0.0027
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0037 0.0216 0.0268
Mycobacterium ulcerans integral membrane transport protein 0.0033 0.0184 0.104
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0083 0.0683 0.2223
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0027
Echinococcus multilocularis solute carrier family 22 0.0033 0.0184 0.019
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0042 0.0047
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0033 0.0184 0.0247
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0244 0.2307 0.311
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0046 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0062 0.0086
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0047 0.0103
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0062 0.0083
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.045 0.0584
Brugia malayi serine/threonine-protein kinase plk-2 0.0115 0.1011 0.1933
Toxoplasma gondii melibiase subfamily protein 0.0107 0.0923 0.1395
Brugia malayi major facilitator superfamily protein 0.0033 0.0184 0.0323
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0062 0.0086
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0128 0.0214
Brugia malayi Cation transporter family protein 0.0037 0.0216 0.0386
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0032 0.0053
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0032 0.0019
Plasmodium falciparum proline--tRNA ligase 0.0083 0.0683 0.0657
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.1031 0.6733
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0046 0.0102
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0784
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0028 0.0013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0522 0.0681
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.037 0.0498
Schistosoma mansoni ran 0.0021 0.0056 0.0076
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0046 0.0062
Schistosoma mansoni hypothetical protein 0.0072 0.0573 0.0772
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0062 0.0086
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0056 0.0075
Entamoeba histolytica hypothetical protein 0.0027 0.012 0.0598
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0056 0.0075
Onchocerca volvulus 0.0033 0.0184 0.037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0033 0.0184 0.019
Onchocerca volvulus 0.0194 0.1808 0.3997
Leishmania major glucose transporter/membrane transporter D2, putative 0.0073 0.0588 0.1908
Schistosoma mansoni survival motor neuron protein 0.0107 0.0931 0.1255
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0685 0.2598
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0216 0.0386
Brugia malayi Melibiase family protein 0.0071 0.0565 0.1064
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0032 0.0004
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0172 0.1585 0.523
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0216 0.0268
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0046 0.0055
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0043 0.0092
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0046 0.0062
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0033 0.0184 0.0559
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Brugia malayi Importin beta-1 subunit 0.0028 0.0131 0.022
Trypanosoma cruzi metacaspase, putative 0.0083 0.0685 0.223
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0135 0.1211 0.1613
Echinococcus granulosus General substrate transporter 0.0204 0.19 0.2543
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Brugia malayi Pre-SET motif family protein 0.0227 0.2138 0.4126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0062 0.0086
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0074 0.0598 0.0572
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0074 0.0598 0.1129
Leishmania major hypothetical protein, conserved 0.0033 0.0184 0.0559
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0172 0.1585 0.523
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1211 0.7896
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Onchocerca volvulus 0.0037 0.0216 0.0443
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0033 0.0184 0.104
Onchocerca volvulus Putative transporter 0.0033 0.0184 0.037
Trypanosoma brucei hypothetical protein, conserved 0.0246 0.233 0.7712
Leishmania major cathepsin L-like protease 0.0018 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Loa Loa (eye worm) glutathione reductase 0.0051 0.0367 0.0679
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Treponema pallidum bacterioferrin (TpF1) 0.0019 0.0038 0.007
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0172 0.1585 0.523
Echinococcus multilocularis caspase 2 0.0212 0.1986 0.2256
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Trichomonas vaginalis sugar transporter, putative 0.0073 0.0588 0.2216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0184 0.0616
Leishmania major cathepsin L-like protease 0.0018 0.0032 0.0053
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0032 0.0031
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0396 0.1268
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0159 0.1448 0.1639
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0834 0.0935
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0037 0.0216 0.0227
Plasmodium falciparum calcium-dependent protein kinase 2 0.0074 0.0598 0.0572
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0216 0.0386
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0461 0.1484
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0083 0.0683 0.2223
Schistosoma mansoni sugar transporter 0.0033 0.0184 0.0247
Plasmodium falciparum calcium-dependent protein kinase 1 0.0074 0.0598 0.0572
Brugia malayi Sugar transporter family protein 0.0237 0.2235 0.4315
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Echinococcus multilocularis caspase 8 0.0083 0.0685 0.0765
Brugia malayi hypothetical protein 0.0129 0.1149 0.2201
Onchocerca volvulus 0.0033 0.0184 0.037
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0487 0.157
Schistosoma mansoni hypothetical protein 0.0024 0.0094 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Echinococcus multilocularis neuropeptide s receptor 0.0505 0.4938 0.5638
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0183 0.0246
Toxoplasma gondii sugar transporter ST1 0.0033 0.0184 0.0278
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0083 0.0683 0.1033
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0071 0.0564 0.1063
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.1518 0.5006
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Echinococcus granulosus nAChR subunit 0.002 0.0046 0.0039
Echinococcus multilocularis neuropeptide receptor A26 0.0505 0.4938 0.5638
Loa Loa (eye worm) hypothetical protein 0.0167 0.1526 0.2936
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0043 0.01
Mycobacterium ulcerans hypothetical protein 0.0028 0.0134 0.0708
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0062 0.0086
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0367 0.1169
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0046 0.0102
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0043 0.0105
Echinococcus granulosus geminin 0.0176 0.1626 0.2173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0062 0.0086
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0908 0.1733
Brugia malayi hypothetical protein 0.0033 0.0184 0.0323
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0062 0.006
Onchocerca volvulus 0.0018 0.0032 0.0031
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0046 0.0102
Trypanosoma brucei protein kinase, putative 0.0172 0.1585 0.523
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0293 0.0926
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Giardia lamblia Kinase, CMGC MAPK 0.0172 0.1585 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.06 0.1132
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0035 0.002
Trypanosoma cruzi hexose transporter, putative 0.0073 0.0588 0.1908
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Trypanosoma cruzi metacaspase 5, putative 0.0083 0.0685 0.223
Echinococcus granulosus serine protein kinase ATM 0.0027 0.012 0.0139
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0046 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0062 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.012 0.0367
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0028 0.0019
Schistosoma mansoni neurotransmitter gated ion channel 0.0017 0.0018 0.0024
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.1626 0.3591
Brugia malayi hypothetical protein 0.0035 0.0202 0.0358
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2541
Loa Loa (eye worm) hypothetical protein 0.0052 0.037 0.0685
Brugia malayi PHD-finger family protein 0.0029 0.014 0.0238
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0128 0.0396
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0183 0.0321
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0062 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.1031 0.6672
Chlamydia trachomatis proline--tRNA ligase 0.0025 0.0101 0.0489
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0057 0.0426 0.04
Brugia malayi nuclear hormone receptor 0.0021 0.0062 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0598 0.2253
Schistosoma mansoni bromodomain containing protein 0.0071 0.0561 0.0756
Onchocerca volvulus Cell death protein 3 homolog 0.0212 0.1986 0.4395
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0131 0.1163 0.7619
Trypanosoma cruzi metacaspase, putative 0.0083 0.0685 0.223
Onchocerca volvulus 0.0018 0.0032 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0548 0.1773
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Loa Loa (eye worm) hypothetical protein 0.0244 0.2307 0.4455
Mycobacterium tuberculosis Probable oxidoreductase 0.0131 0.1163 0.7619
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0028 0.004
Trypanosoma brucei metacaspase 5, putative 0.0083 0.0685 0.223
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0685 0.0659
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0037 0.0216 0.0227
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0028 0.0042
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0037 0.0216 0.0386
Schistosoma mansoni ferritin 0.0019 0.0038 0.0051
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0053 0.0381 0.1396
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0216 0.0268
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0565 0.0761
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0461 0.1484
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0083 0.0685 0.1036
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.1031 0.6733
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0685 0.2598
Toxoplasma gondii exonuclease III APE 0.0019 0.0043 0.0065
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0908 0.1733
Echinococcus multilocularis Protein lozenge 0.0058 0.0431 0.0473
Onchocerca volvulus 0.0018 0.0032 0.0031
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.045 0.2833
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.1518 0.5006
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0019 0.0038 0.0071
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.1348 0.4438
Trypanosoma cruzi hypothetical protein, conserved 0.0246 0.233 0.7712
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0172 0.1585 0.523
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus granulosus solute carrier family 22 0.0033 0.0184 0.0224
Schistosoma mansoni acetylcholine receptor-related 0.0017 0.0018 0.0024
Leishmania major lysyl-tRNA synthetase, putative 0.0053 0.0381 0.1216
Treponema pallidum prolyl-tRNA synthetase 0.0025 0.0101 0.0489
Schistosoma mansoni hypothetical protein 0.0176 0.1626 0.2192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0056 0.0183
Trypanosoma brucei THT1 - hexose transporter, putative 0.0073 0.0588 0.1908
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0062 0.005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.06 0.3822
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0037 0.0216 0.0386
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0062 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0167 0.1526 0.1503
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0062 0.0083
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0053 0.0381 0.1216
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0216 0.0291
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0391 0.125
Brugia malayi Cathepsin L-like precursor 0.0018 0.0032 0.0027
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0071 0.0564 0.3583
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0247
Plasmodium falciparum glutathione reductase 0.0051 0.0367 0.034
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0062 0.0083
Brugia malayi steroid hormone receptor 0.0021 0.0062 0.0086
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0071 0.0565 0.2122
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0541 0.1017
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.1348 0.4438
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.1518 0.5006
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.1517 0.9994
Echinococcus granulosus peptidase Clp S14 family 0.0109 0.0948 0.1257
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0028 0.004
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0315 0.1136
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0053 0.0381 0.2356
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0074 0.0598 0.1129
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0216 0.0386
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0043 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0685 0.2598
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 0.1503
Trichomonas vaginalis ferritin, putative 0.0019 0.0038 0.0042
Treponema pallidum phosphoglycerate kinase 0.0166 0.1518 0.9945
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Loa Loa (eye worm) hypothetical protein 0.0527 0.5157 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.1348 0.4438
Brugia malayi Cam kinase protein 1 0.0074 0.0598 0.1129
Loa Loa (eye worm) hypothetical protein 0.0227 0.2137 0.4124
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0247
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0043 0.0092
Brugia malayi Cathepsin L-like precursor 0.0018 0.0032 0.0027
Echinococcus granulosus expressed protein 0.0019 0.0038 0.0028
Brugia malayi Sugar transporter family protein 0.0033 0.0184 0.0323
Onchocerca volvulus 0.0021 0.0062 0.0098
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0062 0.005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.045 0.2817
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0062 0.0086
Trypanosoma cruzi hexose transporter 0.0073 0.0588 0.1908
Onchocerca volvulus 0.0033 0.0184 0.037
Plasmodium falciparum calcium-dependent protein kinase 4 0.0074 0.0598 0.0572
Onchocerca volvulus 0.0033 0.0184 0.037
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0461 0.1484
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0183 0.0246
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0037 0.0216 0.0291
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0043 0.005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0367 0.2274
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.1031 0.6733
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0037 0.0216 0.0268
Leishmania major glucose transporter, lmgt1 0.0073 0.0588 0.1908
Plasmodium falciparum lysine--tRNA ligase 0.0053 0.0381 0.0354
Mycobacterium ulcerans hypothetical protein 0.0166 0.1517 0.9939
Leishmania major cathepsin L-like protease 0.0069 0.0548 0.1773
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.0184 0.0323
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0216 0.0227
Echinococcus granulosus glycine receptor subunit beta 0.0037 0.0216 0.0268
Schistosoma mansoni sugar transporter 0.0033 0.0184 0.0247
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0028 0.004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0046 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0216 0.0386
Loa Loa (eye worm) hypothetical protein 0.0071 0.0564 0.1063
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0043 0.0104
Echinococcus granulosus mitogen activated protein kinase 3 0.0172 0.1585 0.2118
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0037 0.0216 0.0386
Plasmodium falciparum metacaspase-like protein 0.0083 0.0685 0.0659
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.3017 1
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.1518 0.5891
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.1518 0.2046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Schistosoma mansoni hypothetical protein 0.0129 0.1149 0.1549
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trichomonas vaginalis glucose transporter, putative 0.0073 0.0588 0.2216
Plasmodium vivax CDK-related protein kinase 6, putative 0.1007 1 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0057 0.0426 0.2659
Loa Loa (eye worm) sugar transporter 0.0033 0.0184 0.0323
Echinococcus granulosus neuropeptide s receptor 0.0505 0.4938 0.6648
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0062 0.0083
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0521 0.0788
Echinococcus multilocularis GPCR, family 2 0.0033 0.0183 0.019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0062 0.0086
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0046 0.0102
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0216 0.0268
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0834 0.0935
Echinococcus multilocularis calcium dependent protein kinase 0.0068 0.0534 0.0591
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0923 0.1244
Schistosoma mansoni protein kinase 0.0074 0.0598 0.0806
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0923 0.1244
Mycobacterium ulcerans bacterioferritin BfrA 0.0019 0.0038 0.007
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0074 0.0598 0.1129
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0062 0.0098
Brugia malayi Phosphoglycerate kinase 0.0061 0.0461 0.0862
Brugia malayi Sugar transporter family protein 0.0033 0.0184 0.0323
Onchocerca volvulus 0.0033 0.0184 0.037
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0046 0.007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0128 0.0214
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.012 0.0349
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0784
Trypanosoma brucei trypanothione reductase 0.0051 0.0367 0.1169
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0028 0.004
Trypanosoma cruzi metacaspase, putative 0.0083 0.0685 0.223
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0184 0.0559
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0062 0.006
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0083 0.0685 0.0924
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0212 0.1986 0.383
Schistosoma mansoni cpg binding protein 0.0037 0.0223 0.0301
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0033 0.0184 0.1046
Echinococcus granulosus GPCR family 2 0.0033 0.0183 0.0224
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Trypanosoma brucei polo-like protein kinase 0.0115 0.1011 0.3316
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0032 0.0019
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0071 0.0564 0.212
Onchocerca volvulus 0.0033 0.0184 0.037
Onchocerca volvulus 0.0037 0.0216 0.0443
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0115 0.1011 0.3316
Chlamydia trachomatis phosphoglycerate kinase 0.0166 0.1518 0.9945
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0216 0.0227
Echinococcus granulosus Sugar transporter ERD6 protein 0.0033 0.0184 0.0224
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0028 0.004
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0056 0.0085
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.06 0.1132
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Onchocerca volvulus 0.0018 0.0032 0.0031
Echinococcus granulosus nAChR subunit 0.0037 0.0216 0.0268
Trypanosoma brucei THT1 - hexose transporter, putative 0.0073 0.0588 0.1908
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.1518 0.9945
Schistosoma mansoni importin beta-1 0.0028 0.0131 0.0176
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0046 0.0055
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.1518 0.1719
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0461 0.1484
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Leishmania major myo-inositol/proton symporter (MIT) 0.0033 0.0184 0.0559
Toxoplasma gondii transporter, major facilitator family protein 0.0033 0.0184 0.0278
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0033 0.0184 0.104
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.045 0.2817
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0172 0.1585 0.523
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0184 0.0616
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0057 0.0426 0.2607
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0062 0.0098
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.002 0.0046 0.0062
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.06 0.0907
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0056 0.0135
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0033 0.0184 0.1046
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0056 0.0029
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.1211 0.1633
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0046 0.0102
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0834 0.1103
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0056 0.0044
Echinococcus granulosus citrate lyase subunit beta protein 0.0028 0.0134 0.0157
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.06 0.2261
Echinococcus granulosus apoptotic protease activating factor 1 0.0129 0.1149 0.1528
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.2558 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0883 0.8744 1
Brugia malayi Cation transporter family protein 0.0244 0.2307 0.4455
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0541 0.1749
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0071 0.0564 0.0738
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2997
Chlamydia trachomatis lysine--tRNA ligase 0.0053 0.0381 0.2356
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0109 0.0948 0.6176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0131 0.022
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.012 0.0349
Brugia malayi Phosphoglycerate kinase 0.0166 0.1518 0.2919
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Schistosoma mansoni sugar transporter 0.0033 0.0184 0.0247
Brugia malayi Bromodomain containing protein 0.0042 0.0268 0.0487
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0184 0.0616
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.045 0.0606
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.1211 0.1633
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0134 0.0393
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0028 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0035 0.0047
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.1518 0.2296
Onchocerca volvulus 0.0033 0.0183 0.0369
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0037 0.0216 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0685 0.2598
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0114 0.013
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0172 0.1585 0.2398
Trichomonas vaginalis set domain proteins, putative 0.0259 0.2454 0.9589
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Echinococcus multilocularis nAChR subunit 0.002 0.0046 0.0033
Trypanosoma brucei Metacaspase-4 0.0083 0.0685 0.223
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0923 0.1244
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0062 0.005
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.0184 0.0323
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0037 0.0216 0.0386
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0032 0.0016
Brugia malayi ecdysteroid receptor 0.0021 0.0062 0.0086
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0183 0.0322
Trypanosoma cruzi glucose transporter, putative 0.0033 0.0184 0.0559
Toxoplasma gondii protein kinase, putative 0.0671 0.6612 1
Echinococcus multilocularis glycine receptor subunit beta 0.0037 0.0216 0.0227
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Onchocerca volvulus 0.0033 0.0184 0.037
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0037 0.0216 0.0386
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0216 0.0291
Onchocerca volvulus 0.0244 0.2307 0.5113
Loa Loa (eye worm) hypothetical protein 0.0083 0.0685 0.1299
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0548 0.1773
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0062 0.005
Trichomonas vaginalis ran, putative 0.0021 0.0056 0.0113
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0541 0.1749
Schistosoma mansoni protein kinase 0.0074 0.0598 0.0806
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Plasmodium falciparum mitogen-activated protein kinase 2 0.0385 0.3725 0.3707
Schistosoma mansoni glucose transport protein 0.0237 0.2235 0.3013
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0216 0.0291
Brugia malayi Cathepsin L-like precursor 0.0018 0.0032 0.0027
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0107 0.0923 0.1037
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0135 0.1211 0.3983
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.0931 0.1777
Echinococcus granulosus ferritin 0.0019 0.0038 0.0028
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0077 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.1585 0.6156
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0032 0.0016
Echinococcus granulosus solute carrier family 22 0.0033 0.0184 0.0224
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0134 0.0393
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0037 0.0216 0.0268
Plasmodium vivax sugar transporter, putative 0.0033 0.0184 0.0156
Loa Loa (eye worm) hypothetical protein 0.016 0.1458 0.2802
Loa Loa (eye worm) GABA receptor subunit 0.002 0.0046 0.0056
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0128 0.0648
Brugia malayi CXXC zinc finger family protein 0.0033 0.0183 0.0321
Leishmania major metacaspase, putative 0.0083 0.0685 0.223
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0396 0.0599
Loa Loa (eye worm) hypothetical protein 0.0042 0.0269 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0105 0.0908 0.1733
Trypanosoma cruzi hypothetical protein, conserved 0.0246 0.233 0.7712
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0128 0.0396
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0128 0.0374
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0834 0.1103
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2541
Entamoeba histolytica protein kinase, putative 0.0074 0.0598 0.3809
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0046 0.0055
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0033 0.0184 0.104
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0071 0.0564 0.3534
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0053 0.0381 0.2356
Echinococcus multilocularis muscleblind protein 1 0.016 0.1458 0.165
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0183 0.019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0082 0.0125
Echinococcus multilocularis citrate lyase subunit beta protein 0.0028 0.0134 0.0133
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Toxoplasma gondii hypothetical protein 0.0051 0.0359 0.0543
Schistosoma mansoni coup transcription factor 0.0021 0.0062 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Loa Loa (eye worm) ACC-1 protein 0.0037 0.0216 0.0386
Onchocerca volvulus 0.0033 0.0184 0.037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Loa Loa (eye worm) ACC-1 protein 0.0037 0.0216 0.0386
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0163 0.0197
Onchocerca volvulus 0.0107 0.0931 0.2039
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0046 0.0102
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.1518 0.5006
Trypanosoma cruzi polo-like protein kinase, putative 0.0115 0.1011 0.3316
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0053 0.0381 0.1216
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0037 0.0216 0.0268
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0135 0.1211 0.1368
Plasmodium falciparum metacaspase 1 0.0083 0.0685 0.0659
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0046 0.0055
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.1518 0.2027
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0247
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0046 0.0102
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0454 0.1687
Onchocerca volvulus 0.0033 0.0184 0.037
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0134 0.0393
Loa Loa (eye worm) hypothetical protein 0.0461 0.4496 0.8713
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0062 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.1011 0.1363
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0461 0.1484
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0043 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0032 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0216 0.0386
Schistosoma mansoni neurotransmitter gated ion channel 0.0017 0.0018 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0037 0.0216 0.0386
Loa Loa (eye worm) hypothetical protein 0.0071 0.0565 0.1064
Plasmodium vivax lysine--tRNA ligase, putative 0.0053 0.0381 0.0354
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0094 0.0103
Schistosoma mansoni hypothetical protein 0.0237 0.2235 0.3013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0043 0.0029
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0077 0.0196
Trypanosoma brucei metacaspase 0.0083 0.0685 0.223
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0062 0.0086
Onchocerca volvulus 0.0033 0.0184 0.037
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0183 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0216 0.0386
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0541 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Toxoplasma gondii aldehyde dehydrogenase 0.0135 0.1211 0.1832
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0062 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0083 0.0683 0.2223
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0128 0.0396
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0114 0.0111
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0056
Schistosoma mansoni hypothetical protein 0.0022 0.0074 0.01
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0037 0.0216 0.0227
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0183 0.0224
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0396 0.037
Toxoplasma gondii sugar transporter ST3 0.0033 0.0184 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0074 0.0598 0.0905
Schistosoma mansoni ap endonuclease 0.0019 0.0043 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.06 0.2261
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0046 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.2138 0.4126
Loa Loa (eye worm) LGC-31 protein 0.0037 0.0216 0.0386
Loa Loa (eye worm) fibroinase 0.0018 0.0032 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0115 0.1011 0.1342
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0461 0.1484
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.045 0.0495
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0062 0.006
Trypanosoma cruzi metacaspase, putative 0.0083 0.0685 0.223
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0077 0.0196
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.1518 0.5006
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0057 0.0426 0.04
Echinococcus granulosus snurportin 1 0.03 0.2869 0.3852
Giardia lamblia Lysyl-tRNA synthetase 0.0053 0.0381 0.2267
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0167 0.1526 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0183 0.0322
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0074 0.0598 0.1129
Onchocerca volvulus 0.0018 0.0032 0.0031
Echinococcus multilocularis mitogen activated protein kinase 0.0172 0.1585 0.1796
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0028 0.004
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.06 0.2261
Trichomonas vaginalis sugar transport protein, putative 0.0033 0.0184 0.0616
Brugia malayi Thioredoxin reductase 0.0051 0.0367 0.0679
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0032 0.0016
Leishmania major cathepsin L-like protease 0.0018 0.0032 0.0053
Mycobacterium tuberculosis Probable reductase 0.0117 0.1031 0.6733
Onchocerca volvulus 0.0033 0.0183 0.0368
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.037 0.0476
Loa Loa (eye worm) major facilitator superfamily transporter 0.0033 0.0184 0.0323
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0028 0.0037
Onchocerca volvulus 0.002 0.0046 0.0064
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0046 0.0062
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0037 0.0216 0.0227
Onchocerca volvulus 0.0033 0.0184 0.037
Onchocerca volvulus 0.0129 0.1149 0.2526
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.3236 0.3688
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0396 0.037
Onchocerca volvulus 0.0018 0.0032 0.0031
Leishmania major cathepsin L-like protease 0.0018 0.0032 0.0053
Schistosoma mansoni lozenge 0.0058 0.0431 0.0581
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0062 0.0086
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Loa Loa (eye worm) hypothetical protein 0.0044 0.0295 0.0539
Leishmania major GTP-binding protein, putative 0.0021 0.0056 0.0135
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0062 0.0083
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.045 0.1446
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Echinococcus multilocularis glycine receptor subunit beta 0.0037 0.0216 0.0227
Schistosoma mansoni ap endonuclease 0.0019 0.0043 0.0058
Brugia malayi hypothetical protein 0.0033 0.0184 0.0323
Giardia lamblia GTOR 0.002 0.0046 0.012
Trypanosoma brucei THT1 - hexose transporter, putative 0.0073 0.0588 0.1908
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0183 0.0322
Echinococcus multilocularis survival motor neuron protein 1 0.0527 0.5157 0.5889
Echinococcus granulosus solute carrier family 22 0.0033 0.0184 0.0224
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0046 0.0056
Plasmodium falciparum protein kinase 7 0.0671 0.6612 0.6603
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.1518 0.2296
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0131 0.1163 0.7619
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.06 0.0667
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0784
Leishmania major trypanothione reductase 0.0051 0.0367 0.1169
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.06 0.1946
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0032 0.0004
Giardia lamblia Hexose transporter 0.0033 0.0184 0.1001
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0237 0.2235 0.2541
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0244 0.2307 0.311
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0571 0.0769
Brugia malayi Cation transporter family protein 0.0037 0.0216 0.0386
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0183 0.019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.012 0.02
Giardia lamblia Phosphoglycerate kinase 0.0166 0.1518 0.9568
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0062 0.0086
Brugia malayi major facilitator superfamily protein 0.0033 0.0184 0.0323
Echinococcus granulosus caspase 2 0.0212 0.1986 0.266
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0037 0.0216 0.0386
Brugia malayi hypothetical protein 0.0054 0.0396 0.0736
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0336 0.3236 0.6263
Schistosoma mansoni peptidase Clp (S14 family) 0.0167 0.1526 0.2058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0028 0.004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0062 0.0086
Echinococcus granulosus lysosomal alpha glucosidase 0.0336 0.3236 0.4349
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0082 0.0222
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0541 0.0729
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0043 0.0016
Schistosoma mansoni hypothetical protein 0.0107 0.0931 0.1255
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0028 0.0134 0.0419
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Entamoeba histolytica Ran family GTPase 0.0021 0.0056 0.0165
Echinococcus granulosus calcium dependent protein kinase 0.0068 0.0534 0.0697
Leishmania major protein kinase, putative 0.0074 0.0598 0.1939
Loa Loa (eye worm) hypothetical protein 0.0244 0.2307 0.4455
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0028 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0062 0.006
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0367 0.0471
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0083 0.0685 0.1036
Echinococcus granulosus caspase 8 0.0083 0.0685 0.0902
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0071 0.0564 0.076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1211 0.7896
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.1585 0.6156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.0046 0.0102
Echinococcus multilocularis lysyl tRNA synthetase 0.0053 0.0381 0.0416
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.0184 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0107 0.0923 0.1037
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0249 0.0265
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0074 0.0598 0.0572
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Echinococcus granulosus neuropeptide receptor A26 0.0505 0.4938 0.6648
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0541 0.1749
Entamoeba histolytica hypothetical protein 0.002 0.0046 0.0099
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.3017 1
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Loa Loa (eye worm) hypothetical protein 0.0461 0.4496 0.8713
Echinococcus granulosus survival motor neuron protein 1 0.0527 0.5157 0.6944
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0269 0.2558 0.4943
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0461 0.1484
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0114 0.0154
Onchocerca volvulus 0.0033 0.0184 0.037
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.06 0.2261
Toxoplasma gondii facilitative glucose transporter GT1 0.0237 0.2235 0.3381
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0045 0.03 0.1762
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.06 0.3822
Echinococcus multilocularis expressed protein 0.0019 0.0038 0.0023
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0062 0.0083
Schistosoma mansoni ran 0.0021 0.0056 0.0076
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0216 0.0386
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.1585 0.2137
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0043 0.0092
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0062 0.005
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.012 0.0118
Trypanosoma brucei glucose transporter 2A 0.0073 0.0588 0.1908
Trypanosoma cruzi hexose transporter, putative 0.0073 0.0588 0.1908
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0367 0.0679
Onchocerca volvulus 0.0244 0.2307 0.5113
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Trichomonas vaginalis sugar transporter, putative 0.0073 0.0588 0.2216
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Brugia malayi hypothetical protein 0.0461 0.4496 0.8713
Onchocerca volvulus 0.0461 0.4496 1
Trypanosoma cruzi metacaspase 5, putative 0.0083 0.0685 0.223
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0128 0.0374
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0565 0.0761
Echinococcus granulosus muscleblind protein 0.016 0.1458 0.1946
Toxoplasma gondii FATC domain-containing protein 0.0027 0.012 0.0182
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0037 0.0216 0.0386
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0028 0.0134 0.0708
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0062 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0367 0.04
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0834 0.1124
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0077 0.0196
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0043 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Plasmodium falciparum thioredoxin reductase 0.0051 0.0367 0.034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0074 0.0598 0.1939
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0083 0.0685 0.1299
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0159 0.1448 0.1933
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0037 0.0216 0.0386
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0573 0.108
Toxoplasma gondii thioredoxin reductase 0.0051 0.0367 0.0554
Trypanosoma cruzi hexose transporter, putative 0.0073 0.0588 0.1908
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0028 0.004
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0293 0.0926
Echinococcus granulosus mitogen activated protein kinase 0.0172 0.1585 0.2118
Schistosoma mansoni cpg binding protein 0.0033 0.0183 0.0247
Toxoplasma gondii hypothetical protein 0.0057 0.0426 0.0644
Trypanosoma brucei glucose transporter, putative 0.0073 0.0588 0.1908
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Entamoeba histolytica hypothetical protein 0.0023 0.0077 0.0308
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0128 0.0396
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0665
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0046 0.0033
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0398 0.1274
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0062 0.0098
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0062 0.0083
Brugia malayi Bromodomain containing protein 0.0084 0.069 0.1308
Entamoeba histolytica serine/threonine protein kinase, putative 0.0115 0.1011 0.6589
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0037 0.0216 0.0268
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0037 0.0216 0.0227
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0032 0.0016
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0056 0.0029
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.0046 0.0102
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0834 0.1124
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0032 0.0031
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0035 0.0023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.1031 0.6733
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0167 0.1526 0.2308
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.2558 1
Echinococcus granulosus transcription factor Dp 1 0.004 0.0249 0.0312
Onchocerca volvulus 0.0033 0.0184 0.037
Trichomonas vaginalis myo-inositol transporter, putative 0.0033 0.0184 0.0616
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0172 0.1585 0.523
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 1
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0028 0.0134 0.0712
Schistosoma mansoni acetylcholine receptor subunit beta 0.0017 0.0018 0.0024
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0037 0.0216 0.0268
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0071 0.0564 0.1063
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0037 0.0216 0.0386
Trichomonas vaginalis glucose transporter, putative 0.0073 0.0588 0.2216
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0043 0.0034
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0046 0.0102
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0167 0.1526 0.2308
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.1585 0.6156
Onchocerca volvulus 0.0033 0.0184 0.037
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0071 0.0564 0.076
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.06 0.2261
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0131 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.2558 1
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Trypanosoma brucei glucose transporter 1E 0.0073 0.0588 0.1908
Echinococcus granulosus cathepsin l1 0.0018 0.0032 0.0019
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0131 0.0198
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0062 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0083 0.0685 0.2598
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0046 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1626 0.6317
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0184 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0183 0.0224
Schistosoma mansoni lysyl-tRNA synthetase 0.0053 0.0381 0.0513
Brugia malayi Cell death protein 3 precursor 0.0212 0.1986 0.383
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0046 0.0056
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0216 0.0386
Trypanosoma cruzi hexose transporter, putative 0.004 0.0253 0.0789
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0665
Loa Loa (eye worm) hypothetical protein 0.0129 0.1149 0.2201
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0598 0.0665
Plasmodium vivax glutathione reductase, putative 0.0051 0.0367 0.034
Loa Loa (eye worm) hypothetical protein 0.0072 0.0573 0.108
Schistosoma mansoni ferritin light chain 0.0019 0.0038 0.0051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0032 0.0016
Echinococcus granulosus importin subunit beta 1 0.0028 0.0131 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0685 0.2598
Trichomonas vaginalis sugar transporter, putative 0.0073 0.0588 0.2216
Echinococcus multilocularis apoptotic protease activating factor 1 0.0129 0.1149 0.1296
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0131 0.0384
Schistosoma mansoni zinc finger protein 0.0023 0.0082 0.011
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0128 0.0374
Schistosoma mansoni nAChR subunit 0.0017 0.0018 0.0024
Echinococcus multilocularis microtubule associated protein 2 0.0751 0.7418 0.8481
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0043 0.0104
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1722 0.6695
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Plasmodium falciparum calcium-dependent protein kinase 5 0.0074 0.0598 0.0572
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.045 0.0841
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0216 0.0227
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0548 0.1773
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0167 0.1526 0.1729
Entamoeba histolytica hypothetical protein 0.0053 0.0381 0.2349
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0242 0.0257
Brugia malayi Pre-SET motif family protein 0.0033 0.0183 0.0321
Plasmodium vivax SET domain protein, putative 0.0033 0.0183 0.0155
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0037 0.0216 0.0268
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0062 0.0086
Echinococcus multilocularis cysteine protease 0.0018 0.0032 0.0016
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2997
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Echinococcus granulosus synaptic vesicle 2 protein 0.0033 0.0184 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Echinococcus granulosus microtubule associated protein 2 0.0751 0.7418 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0128 0.0396
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0367 0.034
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0094 0.0087
Onchocerca volvulus 0.0259 0.2454 0.544
Loa Loa (eye worm) ctsf protein 0.0018 0.0032 0.0027
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0167 0.1526 0.2038
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0045 0.03 0.1831
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0834 0.1588
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0128 0.0396
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2235 0.2997
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.0046 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0083 0.0683 0.2223
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0083 0.0683 0.2223
Loa Loa (eye worm) hypothetical protein 0.0058 0.043 0.0802
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.2235 0.8726
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0293 0.0926
Echinococcus granulosus solute carrier family 22 0.0033 0.0184 0.0224
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0074 0.0598 0.0784
Schistosoma mansoni ferritin light chain 0.0019 0.0038 0.0051
Brugia malayi hypothetical protein 0.0033 0.0184 0.0323
Brugia malayi Cathepsin L-like precursor 0.0018 0.0032 0.0027
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0074 0.0598 0.0905
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.2304 0.4449
Onchocerca volvulus 0.0018 0.0032 0.0031
Echinococcus multilocularis snurportin 1 0.03 0.2869 0.3267
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0086
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0046 0.0102
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0074 0.011
Loa Loa (eye worm) hypothetical protein 0.0054 0.0396 0.0736
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0062 0.006
Schistosoma mansoni protein kinase 0.0074 0.0598 0.0806
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0046 0.0099
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0025 0.0101 0.0489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Brugia malayi nuclear receptor NHR-88 0.0021 0.0062 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0032 0.0016
Plasmodium falciparum importin beta, putative 0.0028 0.0131 0.0103
Echinococcus multilocularis cysteine protease 0.0018 0.0032 0.0016
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0385 0.3725 0.3707
Schistosoma mansoni nAChR subunit 0.0037 0.0216 0.0291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0032 0.0016
Brugia malayi Muscleblind-like protein 0.016 0.1458 0.2802
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0046 0.0039
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0083 0.0685 0.1036
Onchocerca volvulus Serine\/threonine kinase homolog 0.0115 0.1011 0.2218
Giardia lamblia Prolyl-tRNA synthetase 0.0071 0.0564 0.3444
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0056 0.0135
Echinococcus multilocularis mitogen activated protein kinase 3 0.0172 0.1585 0.1796
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0128 0.0396
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0037 0.0216 0.0386
Onchocerca volvulus 0.0033 0.0184 0.037
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0541 0.1017
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 1
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0056 0.0052
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0046 0.0102
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.1518 0.2046
Loa Loa (eye worm) hypothetical protein 0.0077 0.0624 0.1179
Leishmania major cathepsin L-like protease 0.0069 0.0548 0.1773
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Trypanosoma cruzi polo-like protein kinase, putative 0.0115 0.1011 0.3316
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0109 0.0948 0.6176
Brugia malayi lysyl-tRNA synthetase 0.0053 0.0381 0.0706
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Schistosoma mansoni caspase-7 (C14 family) 0.0159 0.1448 0.1952
Echinococcus multilocularis caspase 3 0.0076 0.0611 0.068
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0046 0.0062
Schistosoma mansoni hypothetical protein 0.0474 0.4621 0.6229
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0074 0.0598 0.0905
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Loa Loa (eye worm) sugar transporter 0.0237 0.2235 0.4315
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0046 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0242 0.0303
Echinococcus multilocularis muscleblind protein 0.016 0.1458 0.165
Mycobacterium ulcerans sugar transporter 0.0033 0.0184 0.104
Echinococcus multilocularis synaptic vesicle 2 protein 0.0033 0.0184 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1722 0.6695
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0062 0.0086
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0032 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0548 0.1773
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0046 0.0074
Mycobacterium ulcerans hypothetical protein 0.0028 0.0134 0.0708
Schistosoma mansoni cpg binding protein 0.0037 0.0223 0.0301
Leishmania major cathepsin L-like protease 0.0069 0.0548 0.1773
Schistosoma mansoni nAChR subunit 0.0017 0.0018 0.0024
Schistosoma mansoni hypothetical protein 0.0033 0.0183 0.0247
Entamoeba histolytica protein kinase, putative 0.0074 0.0598 0.3809
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0062 0.005
Echinococcus multilocularis caspase 0.0159 0.1448 0.1639
Trypanosoma brucei metacaspase MCA2 0.0083 0.0685 0.223
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0548 0.1773
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0588 0.2216
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0167 0.1526 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0115 0.1011 0.1138
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0184 0.0616
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0028 0.0134 0.0708
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.1518 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0135 0.1211 0.794
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1211 0.7896
Echinococcus multilocularis ferritin 0.0019 0.0038 0.0023
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0062 0.0083
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0269 0.2558 0.4943
Loa Loa (eye worm) hypothetical protein 0.0037 0.0216 0.0386
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.012 0.0162
Echinococcus multilocularis zinc finger protein 0.0023 0.0082 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.1011 0.3887
Echinococcus granulosus glycine receptor subunit beta 0.0037 0.0216 0.0268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0062 0.006
Plasmodium vivax hexose transporter 0.0237 0.2235 0.2214
Schistosoma mansoni apoferritin-2 0.0019 0.0038 0.0051
Brugia malayi Cathepsin L-like precursor 0.0018 0.0032 0.0027

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.