Detailed information for compound 619580

Basic information

Technical information
  • TDR Targets ID: 619580
  • Name: N-(3-cyanothiophen-2-yl)-5-nitrothiophene-2-c arboxamide
  • MW: 279.295 | Formula: C10H5N3O3S2
  • H donors: 1 H acceptors: 4 LogP: 3.22 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccsc1NC(=O)c1ccc(s1)[N+](=O)[O-]
  • InChi: 1S/C10H5N3O3S2/c11-5-6-3-4-17-10(6)12-9(14)7-1-2-8(18-7)13(15)16/h1-4H,(H,12,14)
  • InChiKey: NHDFDUQLJAEMNW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-cyano-2-thienyl)-5-nitro-thiophene-2-carboxamide
  • N-(3-cyano-2-thienyl)-5-nitro-2-thiophenecarboxamide
  • N-(3-cyanothiophen-2-yl)-5-nitro-thiophene-2-carboxamide
  • ZINC02642307

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0052 0.0052
Onchocerca volvulus 0.0041 0.0052 0.0232
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.0222 0.0222
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0354 0.0819 1
Brugia malayi MBOAT family protein 0.0354 0.0819 0.0819
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0218 0.09
Trypanosoma cruzi GUP1, putative 0.0354 0.0819 1
Mycobacterium ulcerans lipase LipD 0.0108 0.0218 0.3074
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0051 0.0051
Trypanosoma brucei glycerol uptake protein, putative 0.0354 0.0819 1
Echinococcus granulosus tumor protein p63 0.0332 0.0764 0.0764
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0006 0.0006
Trypanosoma cruzi glycerol uptake protein, putative 0.0354 0.0819 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0006 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0052 0.0052
Brugia malayi Hhat protein 0.0354 0.0819 0.0819
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0149 0.0319 0.0319
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0354 0.0819 1
Schistosoma mansoni ap endonuclease 0.0038 0.0046 0.0046
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0303 0.0695 0.0695
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Brugia malayi hypothetical protein 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0029 0.0024 0.0109
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0029 0.0024 0.026
Mycobacterium ulcerans hypothetical protein 0.0155 0.0332 0.4724
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0149 0.0319 0.0319
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0068 0.0068
Loa Loa (eye worm) cytochrome P450 family protein 0.0108 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0354 0.0819 0.0819
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0033 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0739 0.1762 0.1762
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.0218 0.1291
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0054 0.0376
Schistosoma mansoni aldehyde dehydrogenase 0.0303 0.0695 0.0695
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0062 0.0062
Echinococcus multilocularis RUN 0.004 0.0051 0.0051
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0052 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0204 0.0204
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0149 0.0319 0.1347
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0246 0.0555 0.0555
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.0672 0.8148
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0029 0.0024 0.0109
Trypanosoma cruzi glycerol uptake protein, putative 0.0354 0.0819 1
Loa Loa (eye worm) MBOAT family protein 0.0354 0.0819 0.0819
Toxoplasma gondii hypothetical protein 0.0047 0.0069 0.0771
Mycobacterium leprae conserved hypothetical protein 0.0108 0.0218 0.6585
Brugia malayi nuclear hormone receptor 0.0041 0.0052 0.0052
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0354 0.0819 0.0819
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0108 0.0218 0.1291
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0076 0.0654
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0354 0.0819 0.0819
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0692 0.1646 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0303 0.0695 1
Schistosoma mansoni lipoxygenase 0.0178 0.0388 0.0388
Schistosoma mansoni cpg binding protein 0.012 0.0248 0.0248
Trichomonas vaginalis set domain proteins, putative 0.0943 0.2259 1
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0051 0.055
Echinococcus granulosus survival motor neuron protein 1 0.0464 0.1089 0.1089
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0354 0.0819 1
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0052 0.0052
Mycobacterium leprae Probable lipase LipE 0.0108 0.0218 0.6585
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0029 0.0024 0.026
Entamoeba histolytica hypothetical protein 0.011 0.0222 0.227
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0029 0.0024 0.026
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0029 0.0024 0.0109
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0204 0.0835
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0149 0.0319 0.0319
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0249 0.0249
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0046 0.0578
Brugia malayi CXXC zinc finger family protein 0.0114 0.0232 0.0232
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0114 0.0232 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0029 0.0024 0.026
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0354 0.0819 0.0819
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0052 0.0052
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0354 0.0819 0.0819
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0153 0.0328 0.1961
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0052 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0218 0.2438
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0153 0.0328 0.4668
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0218 0.2438
Schistosoma mansoni rab6-interacting 0.004 0.0051 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.0514 0.0514
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.0218 0.1291
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0125 0.0258 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0049 0.0072 0.0072
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0046 1
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0029 0.0024 0.026
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0029 0.0024 0.0109
Loa Loa (eye worm) CYP4Cod1 0.0047 0.0068 0.0068
Brugia malayi Muscleblind-like protein 0.0739 0.1762 0.1762
Brugia malayi hypothetical protein 0.0049 0.0074 0.0074
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0029 0.0024 0.0109
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.0319 0.3701
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0178 0.0388 0.0388
Toxoplasma gondii histone lysine methyltransferase SET1 0.0224 0.0501 0.6084
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0029 0.0024 0.0109
Schistosoma mansoni hypothetical protein 0.0354 0.0819 0.0819
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0006 0.0006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.0319 0.3701
Echinococcus multilocularis dnaJ subfamily B 0.1221 0.2942 0.2942
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0249 0.0249
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0314 0.0314
Echinococcus multilocularis survival motor neuron protein 1 0.0464 0.1089 0.1089
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0204 0.0204
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0006 0.5
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0029 0.0024 0.0109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0332 0.1984
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0354 0.0819 1
Loa Loa (eye worm) acetyltransferase 0.0152 0.0324 0.0324
Schistosoma mansoni hypothetical protein 0.0033 0.0035 0.0035
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0052 0.0052
Toxoplasma gondii exonuclease III APE 0.0038 0.0046 0.049
Loa Loa (eye worm) hypothetical protein 0.0354 0.0819 0.0819
Schistosoma mansoni cytochrome P450 0.0029 0.0024 0.0024
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0074 0.0827
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.0672 0.8148
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0052 0.0052
Brugia malayi ecdysteroid receptor 0.0041 0.0052 0.0052
Schistosoma mansoni cpg binding protein 0.0114 0.0232 0.0232
Brugia malayi nuclear receptor RXR 0.0021 0.0006 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0073 0.0073
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0125 0.0258 0.0258
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0068 0.0555
Mycobacterium ulcerans beta-lactamase 0.0108 0.0218 0.3074
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.1221 0.2942 0.2942
Onchocerca volvulus 0.0121 0.0249 0.1103
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0204 0.0204
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0354 0.0819 0.0819
Entamoeba histolytica vacuolar protein sorting 26 0.0354 0.0819 1
Brugia malayi follicle stimulating hormone receptor 0.0229 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.004 0.0051 0.0051
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0004 0.0004
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0062 0.0688
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0052 0.0052
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0204 0.2256
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.0514 0.0514
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0046 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0029 0.0024 0.0109
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0029 0.0024 0.026
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0204 0.2256
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0324 0.0324
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0354 0.0819 0.0819
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0354 0.0819 0.0819
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0046 0.0046
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.005 0.005
Echinococcus multilocularis ubiquitin specific protease 41 0.0149 0.0319 0.0319
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0033 0.0033
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0354 0.0819 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0229 0.0514 0.0514
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0052 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0204 0.0835
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0029 0.0024 0.026
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0153 0.0328 0.1389
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.0218 0.1291
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0073 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0046 0.0276
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0149 0.0319 0.3523
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0047 0.0068 0.0901
Schistosoma mansoni aldehyde dehydrogenase 0.0303 0.0695 0.0695
Trypanosoma brucei glycerol uptake protein, putative 0.0354 0.0819 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0007 0.0007
Brugia malayi beta-lactamase family protein 0.0108 0.0218 0.0218
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.0222 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0052 0.0052
Loa Loa (eye worm) CXXC zinc finger family protein 0.0114 0.0232 0.0232
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0204 0.0835
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0073
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0204 0.2427
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0029 0.0024 0.0109
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0204 0.2256
Mycobacterium tuberculosis Conserved protein 0.0108 0.0218 0.1291
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0029 0.0024 0.026
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0051 0.0051
Toxoplasma gondii hypothetical protein 0.0354 0.0819 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0029 0.0024 0.026
Schistosoma mansoni coup transcription factor 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0108 0.0218 0.0218
Schistosoma mansoni loxhd1 0.004 0.0051 0.0051
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0029 0.0024 0.026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0052 0.0052
Echinococcus multilocularis sterol O acyltransferase 1 0.0354 0.0819 0.0819
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0121 0.0249 0.0249
Loa Loa (eye worm) hhat protein 0.0354 0.0819 0.0819
Trypanosoma cruzi glycerol uptake protein, putative 0.0354 0.0819 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0293 0.3384
Loa Loa (eye worm) histone methyltransferase 0.004 0.005 0.005
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0052 0.0052
Brugia malayi hypothetical protein 0.0032 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0319 0.1347
Echinococcus multilocularis cpg binding protein 0.012 0.0248 0.0248
Echinococcus multilocularis zinc finger protein 0.3752 0.9134 0.9134
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0052 0.0052
Entamoeba histolytica hypothetical protein 0.011 0.0222 0.227
Mycobacterium ulcerans aldehyde dehydrogenase 0.0303 0.0695 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0006 0.0006
Echinococcus multilocularis muscleblind protein 1 0.0739 0.1762 0.1762
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0149 0.0319 0.0319
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0052 0.0232
Brugia malayi MBOAT family protein 0.0354 0.0819 0.0819
Trichomonas vaginalis transmembrane protein nessy, putative 0.0354 0.0819 0.3579
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0218 0.0218
Schistosoma mansoni cpg binding protein 0.012 0.0248 0.0248
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0052 0.0052
Brugia malayi steroid hormone receptor 0.0041 0.0052 0.0052
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0074 0.062
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0324 0.0324
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0052 0.0052
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0293 0.3384
Loa Loa (eye worm) hypothetical protein 0.0049 0.0074 0.0074
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.0218 0.2438
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0354 0.0819 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.0218 0.1291
Schistosoma mansoni zinc finger protein 0.4106 1 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0672 0.8148
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0062 0.0688
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0153 0.0328 1
Echinococcus granulosus Aminotransferase class III 0.0022 0.0006 0.0006
Onchocerca volvulus 0.0108 0.0218 0.0965
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.0514 0.0514
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0046 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Echinococcus granulosus microtubule associated protein 2 0.1367 0.3297 0.3297
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0051 0.0051
Loa Loa (eye worm) MBOAT family protein 0.0354 0.0819 0.0819
Leishmania major glycerol uptake protein, putative 0.0354 0.0819 1
Brugia malayi Cytochrome P450 family protein 0.0047 0.0068 0.0068
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0051 0.0051
Echinococcus multilocularis tumor protein p63 0.0332 0.0764 0.0764
Mycobacterium ulcerans aldehyde dehydrogenase 0.0303 0.0695 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0171
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0062 0.0688
Brugia malayi MBOAT family protein 0.0354 0.0819 0.0819
Schistosoma mansoni microtubule-associated protein tau 0.1367 0.3297 0.3297
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0029 0.0024 0.026
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0218 0.09
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0218 0.0218
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0052 0.0052
Onchocerca volvulus 0.0354 0.0819 0.3625
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0052 0.0052
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0053 0.009
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0035 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0054 0.0376
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0052 0.0052
Echinococcus granulosus o acyltransferase membrane bound domain 0.0354 0.0819 0.0819
Onchocerca volvulus 0.0108 0.0218 0.0965
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0052 0.0052
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0204 0.2256
Schistosoma mansoni polycystin 1-related 0.004 0.0051 0.0051
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0303 0.0695 0.8439
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.4106 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0354 0.0819 0.3579
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0204 0.2256
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0046 0.049
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0229 0.0514 0.0514
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0046 0.0276
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0029 0.0024 0.026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0229 0.0514 0.0514
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0354 0.0819 0.0819
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0204 0.0204
Echinococcus granulosus zinc finger protein 0.3752 0.9134 0.9134
Loa Loa (eye worm) hypothetical protein 0.0354 0.0819 0.0819
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0052 0.0232
Schistosoma mansoni hypothetical protein 0.0095 0.0185 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0029 0.0024 0.0109
Loa Loa (eye worm) hypothetical protein 0.004 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.0121 0.0249 0.0249
Mycobacterium ulcerans hypothetical protein 0.0108 0.0218 0.3074
Loa Loa (eye worm) hypothetical protein 0.0354 0.0819 0.0819
Brugia malayi beta-lactamase family protein 0.0108 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0121 0.0249 0.0249
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0029 0.0024 0.0109
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0024 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.0514 0.0514
Echinococcus granulosus neuropeptide s receptor 0.0479 0.1124 0.1124
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0006 0.0006
Brugia malayi hypothetical protein 0.004 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0052 0.0052
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0062 0.0205
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0029 0.0024 0.0109
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0054 0.0376
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0052 0.0052
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0354 0.0819 0.0819
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.0319 0.3701
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0068 0.0555
Brugia malayi nuclear receptor NHR-88 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0108 0.0218 0.0218
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0074 0.062
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0249 0.0249
Leishmania major hypothetical protein, conserved 0.0354 0.0819 1
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0354 0.0819 0.0819
Onchocerca volvulus 0.004 0.0051 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0354 0.0819 0.3579
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0029 0.0024 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0052 0.0052
Onchocerca volvulus 0.0943 0.2259 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0052 0.0052
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0029 0.0024 0.0109
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Toxoplasma gondii cytochrome p450 superfamily protein 0.0029 0.0024 0.0221
Echinococcus multilocularis neuropeptide s receptor 0.0479 0.1124 0.1124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0149 0.0319 0.1347
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0029 0.0024 0.026
Onchocerca volvulus 0.0108 0.0218 0.0965
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0204 0.2256
Entamoeba histolytica hypothetical protein 0.011 0.0222 0.227
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0024
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0121 0.0249 0.2987
Echinococcus multilocularis 0.0029 0.0024 0.0024
Brugia malayi hypothetical protein 0.0089 0.0171 0.0171
Schistosoma mansoni survival motor neuron protein 0.0095 0.0185 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0029 0.0024 0.026
Trichomonas vaginalis porcupine, putative 0.0354 0.0819 0.3579
Schistosoma mansoni ap endonuclease 0.0038 0.0046 0.0046
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0029 0.0024 0.026
Onchocerca volvulus 0.0049 0.0072 0.0318
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0029 0.0024 0.026
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0029 0.0024 0.026
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0672 0.8148
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0049 0.0049
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0054 0.0376
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0029 0.0024 0.026
Brugia malayi Cytochrome P450 family protein 0.0108 0.0216 0.0216
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Probable aminotransferase 0.0153 0.0328 0.1961
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0006 0.0006
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0052 0.0052
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0204 0.5782
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0171
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.4106 1 1
Trypanosoma brucei protein kinase, putative 0.0102 0.0204 0.2256
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0229 0.0514 0.0514
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0029 0.0024 0.026
Plasmodium vivax SET domain protein, putative 0.0121 0.0249 0.2987
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0051 0.0051
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0029 0.0024 0.0109
Onchocerca volvulus 0.0095 0.0185 0.0818
Toxoplasma gondii ABC1 family protein 0.0108 0.0218 0.2605
Brugia malayi Doublecortin family protein 0.004 0.0051 0.0051
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0046 0.0046
Echinococcus granulosus dnaJ subfamily B 0.1221 0.2942 0.2942
Entamoeba histolytica hypothetical protein, conserved 0.0354 0.0819 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0121 0.0249 0.0249
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.0218 0.1291
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0052 0.0052
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0074 0.0827
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Trichomonas vaginalis esterase, putative 0.0108 0.0218 0.09
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0007 0.0007
Echinococcus granulosus o acyltransferase membrane bound domain 0.0354 0.0819 0.0819
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0052 0.0052
Echinococcus granulosus cpg binding protein 0.012 0.0248 0.0248
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0229 0.0514 0.0514
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0293 0.3384
Onchocerca volvulus 0.0114 0.0232 0.1026
Loa Loa (eye worm) hypothetical protein 0.0149 0.0319 0.0319
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0029 0.0024 0.0109
Toxoplasma gondii aldehyde dehydrogenase 0.0303 0.0695 0.8474
Loa Loa (eye worm) hypothetical protein 0.0739 0.1762 0.1762
Loa Loa (eye worm) hypothetical protein 0.004 0.0051 0.0051
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0354 0.0819 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0052 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0029 0.0024 0.0109
Brugia malayi hypothetical protein 0.004 0.0051 0.0051
Echinococcus multilocularis microtubule associated protein 2 0.1367 0.3297 0.3297
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0149 0.0319 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0354 0.0819 0.3579
Loa Loa (eye worm) hypothetical protein 0.0464 0.1089 0.1089
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0029 0.0024 0.0109
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0029 0.0024 0.0109
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0178 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0108 0.0218 0.0218
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0046 0.0276
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.0218 0.3074
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0046 0.0134
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0354 0.0819 0.0819
Mycobacterium ulcerans hypothetical protein 0.0153 0.0328 0.4668
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0006 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Mycobacterium tuberculosis Conserved protein 0.0108 0.0218 0.1291
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0035 0.0035
Schistosoma mansoni eyes absent homolog 0.0089 0.0171 0.0171
Schistosoma mansoni transcription factor LCR-F1 0.011 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0108 0.0218 0.0218
Entamoeba histolytica hypothetical protein 0.011 0.0222 0.227
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0149 0.0319 0.0319
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0052 0.0052
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0068 0.0068
Leishmania major hypothetical protein, conserved 0.0049 0.0074 0.062
Schistosoma mansoni lipoxygenase 0.0106 0.0212 0.0212
Leishmania major glycerol uptake protein, putative 0.0354 0.0819 1
Echinococcus multilocularis neuropeptide receptor A26 0.0479 0.1124 0.1124
Brugia malayi hypothetical protein 0.0021 0.0006 0.0006
Echinococcus granulosus ubiquitin specific protease 41 0.0149 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.011 0.0222 0.0222
Brugia malayi MBOAT family protein 0.0354 0.0819 0.0819
Brugia malayi beta-lactamase 0.0108 0.0218 0.0218
Brugia malayi Cytochrome P450 family protein 0.0047 0.0068 0.0068
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0051 0.0051
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0149 0.0319 0.0319
Onchocerca volvulus Huntingtin homolog 0.0125 0.0258 0.1144
Loa Loa (eye worm) hhat protein 0.0354 0.0819 0.0819
Onchocerca volvulus 0.004 0.0051 0.0227
Echinococcus granulosus mixed lineage leukemia protein mll 0.0033 0.0033 0.0033
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0354 0.0819 0.0819
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0053 0.0256
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0052 0.0052
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0052 0.0052
Leishmania major glycerol uptake protein, putative 0.0354 0.0819 1
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0052 0.0232
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0218 0.09
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.0218 0.0218
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0354 0.0819 0.0819
Echinococcus granulosus muscleblind protein 0.0739 0.1762 0.1762
Onchocerca volvulus Huntingtin homolog 0.0125 0.0258 0.1144
Mycobacterium leprae putative cytochrome p450 0.0029 0.0024 0.0558
Brugia malayi hypothetical protein 0.011 0.0222 0.0222
Brugia malayi Pre-SET motif family protein 0.0828 0.198 0.198
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0229 0.0514 0.0514
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0046 0.049
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Loa Loa (eye worm) cytochrome P450 0.0029 0.0024 0.0024
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0052 0.0052
Loa Loa (eye worm) doublecortin family protein 0.004 0.0051 0.0051
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0303 0.0695 0.4201
Treponema pallidum alginate O-acetylation protein (algI) 0.0354 0.0819 1
Echinococcus granulosus sterol O acyltransferase 1 0.0354 0.0819 0.0819
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.0108 0.0218 0.2438
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0046 0.0134
Brugia malayi Cytochrome P450 family protein 0.0029 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0108 0.0218 0.0218
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0185 0.0185
Brugia malayi hypothetical protein 0.0464 0.1089 0.1089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.0218 0.3074
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0006 0.0006
Loa Loa (eye worm) MBOAT family protein 0.4106 1 1
Schistosoma mansoni rab6-interacting 0.004 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0218 0.09
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0062 0.0205
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0006 0.0006
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.0218 0.0218
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0052 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0052 0.0052
Schistosoma mansoni sterol O-acyltransferase 1 0.0354 0.0819 0.0819
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0354 0.0819 0.0819
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0204 0.2256
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0046 0.0276
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0029 0.0024 0.0109
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0204 0.0835
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0354 0.0819 0.0819
Echinococcus granulosus neuropeptide receptor A26 0.0479 0.1124 0.1124
Echinococcus granulosus RUN 0.004 0.0051 0.0051
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.0218 0.1291
Leishmania major glycerol uptake protein, putative 0.0354 0.0819 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0052 0.0052
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0204 0.0204
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.0218 0.0218
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.0218 0.0218
Brugia malayi diacylglycerol acyltransferase 0.0354 0.0819 0.0819
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0204 0.0204
Brugia malayi hypothetical protein 0.0125 0.0258 0.0258
Echinococcus granulosus o acyltransferase membrane bound domain 0.0354 0.0819 0.0819
Brugia malayi MAP kinase sur-1 0.0102 0.0204 0.0204
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0074 0.0827
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0052 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0218 0.2605
Echinococcus multilocularis muscleblind protein 0.0739 0.1762 0.1762
Trypanosoma brucei cytochrome P450, putative 0.0047 0.0068 0.0555
Brugia malayi Pre-SET motif family protein 0.0121 0.0249 0.0249
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.005 0.005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0149 0.0319 0.3701
Trypanosoma cruzi GUP1, putative 0.0354 0.0819 1
Entamoeba histolytica hypothetical protein 0.0354 0.0819 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0052 0.0052
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0828 0.198 0.198
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0354 0.0819 0.0819
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.0218 0.1291
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0033 0.0033
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0074 0.0827
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0354 0.0819 0.0819
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0354 0.0819 0.0819
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0303 0.0695 0.0695
Leishmania major cytochrome p450-like protein 0.0047 0.0068 0.0555
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0046 0.0243
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0072 0.0072
Leishmania major glycerol uptake protein, putative 0.0354 0.0819 1
Loa Loa (eye worm) beta-lactamase 0.0108 0.0218 0.0218
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0121 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0108 0.0218 0.0218
Mycobacterium leprae Conserved hypothetical protein 0.0029 0.0024 0.0558
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0149 0.0319 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0052 0.0052
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0052 0.0052
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0826 0.1974 0.1974
Schistosoma mansoni hypothetical protein 0.0022 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0029 0.0024 0.026
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0053 0.0576
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0354 0.0819 0.0819
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0052 0.0052
Brugia malayi cytochrome P450 0.0029 0.0024 0.0024
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0051 0.055
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0218 0.09
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0074 0.062

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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