Detailed information for compound 63705

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 255.333 | Formula: C12H17NO3S
  • H donors: 4 H acceptors: 3 LogP: 0.54 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1N[C@H](C([C@H]1O)O)CSc1ccccc1
  • InChi: 1S/C12H17NO3S/c14-6-9-11(15)12(16)10(13-9)7-17-8-4-2-1-3-5-8/h1-5,9-16H,6-7H2/t9-,10+,11+,12?/m1/s1
  • InChiKey: SJSFNOKIVMRJHZ-FEZOTEKNSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0118 0.0258
Onchocerca volvulus 0.0215 0.0976 0.3386
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0126 0.0276
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0215 0.0976 1
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.1066 0.3724
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.002 0.0081
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0095 0.0392 0.3943
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.026 0.026
Schistosoma mansoni egf-like domain protein 0.0016 0.001 0.0022
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0215 0.0976 0.3386
Loa Loa (eye worm) hypothetical protein 0.0268 0.1231 0.4298
Echinococcus multilocularis zinc finger protein Ran binding 0.0215 0.0976 0.0976
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0035 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0156 0.0543
Toxoplasma gondii exonuclease III APE 0.0021 0.0034 0.0082
Giardia lamblia Hypothetical protein 0.006 0.0225 0.5332
Onchocerca volvulus 0.0304 0.1407 0.4895
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0118 0.0779
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0095 0.0392 0.3943
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0112 0.0475 0.1659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.063
Loa Loa (eye worm) brahma associated protein 0.0605 0.2864 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0087 0.0087
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0045 0.015 0.1432
Echinococcus multilocularis zinc finger protein 0.0025 0.0053 0.0053
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0605 0.2864 1
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0118 0.0779
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0392 0.1368
Trypanosoma cruzi target of rapamycin kinase 3 0.0075 0.0299 0.2972
Schistosoma mansoni hypothetical protein 0.0053 0.019 0.0417
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0087 0.0777
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0118 0.0258
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0118 0.0779
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0021 0.0046
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0022
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0022
Brugia malayi Bromodomain containing protein 0.0084 0.0339 0.1183
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0118 0.1094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.017 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0095 0.0392 1
Brugia malayi hypothetical protein 0.0016 0.001 0.0035
Schistosoma mansoni microtubule-associated protein tau 0.0676 0.3209 0.7046
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0075 0.0299 0.2972
Echinococcus multilocularis SWI:SNF matrix associated 0.0605 0.2864 0.2864
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0053 0.0422
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0156 0.3407
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0215 0.0976 0.3406
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0087 0.0777
Schistosoma mansoni hypothetical protein 0.0195 0.0879 0.193
Schistosoma mansoni loxhd1 0.0021 0.0035 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Onchocerca volvulus 0.003 0.0077 0.0239
Schistosoma mansoni fusion 0.0215 0.0976 0.2142
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0156 0.365
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0156 0.0543
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0026
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0053 0.0149
Onchocerca volvulus 0.0504 0.2375 0.8288
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.022 0.0219
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0168 0.0745 0.2602
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0156 0.1491
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0095 0.0392 0.0392
Trypanosoma cruzi WLM domain containing protein, putative 0.0215 0.0976 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0034 0.0223
Echinococcus multilocularis bone morphogenetic protein 2 0.0016 0.0009 0.0009
Plasmodium vivax cysteine repeat modular protein 1, putative 0.004 0.0126 0.0325
Schistosoma mansoni netrin 0.0023 0.0043 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.002 0.0069
Onchocerca volvulus 0.0215 0.0976 0.3386
Echinococcus multilocularis lamin dm0 0.003 0.0077 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0205 0.0714
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0035 0.0035
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0034 0.0117
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.002 0.0069
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0272 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.0631
Loa Loa (eye worm) bone morphogenic protein 6 0.0061 0.023 0.0802
Schistosoma mansoni lamin 0.003 0.0077 0.0169
Echinococcus granulosus Smad4 0.0016 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0303
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0095 0.0392 0.0392
Schistosoma mansoni tgf-beta family 0.0016 0.0009 0.0019
Plasmodium vivax SET domain protein, putative 0.0066 0.0252 0.0771
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0118 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0207 0.0723
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0156 0.0543
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0605 0.2864 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.041
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0934 0.4459 0.4459
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0215 0.0976 1
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.003 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0252 0.0552
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0976 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0303
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.017 0.0374
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0215 0.0976 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0053 0.019 0.0663
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0087 0.0303
Giardia lamblia GTOR 0.0095 0.0392 1
Brugia malayi Fibroblast growth factor family protein 0.006 0.0225 0.0784
Echinococcus granulosus zinc finger protein 0.0025 0.0053 0.0053
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0053 0.019 0.019
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.1066 0.3724
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0605 0.2864 1
Schistosoma mansoni hypothetical protein 0.0953 0.4554 1
Brugia malayi Fibulin-1 precursor 0.0016 0.001 0.0035
Echinococcus granulosus geminin 0.0195 0.0879 0.0879
Plasmodium vivax hypothetical protein, conserved 0.0605 0.2864 1
Echinococcus granulosus RUN 0.0021 0.0035 0.0035
Brugia malayi PHD-finger family protein 0.003 0.008 0.028
Trypanosoma brucei hypothetical protein, conserved 0.0215 0.0976 1
Onchocerca volvulus 0.0067 0.0258 0.087
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Brugia malayi Protein kinase domain containing protein 0.0112 0.0475 0.1658
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0156 0.0342
Brugia malayi hypothetical protein 0.0021 0.0035 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0439
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0087 0.0191
Echinococcus granulosus microtubule associated protein 2 0.0676 0.3209 0.3208
Brugia malayi hypothetical protein 0.0025 0.0053 0.0183
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0022
Leishmania major hypothetical protein, conserved 0.0025 0.0053 0.0422
Schistosoma mansoni hypothetical protein 0.0021 0.0035 0.0077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0022
Echinococcus multilocularis survival motor neuron protein 1 0.0268 0.1231 0.1231
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.002 0.0043
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0087 0.0777
Leishmania major hypothetical protein, conserved 0.0038 0.0118 0.1094
Schistosoma mansoni hypothetical protein 0.0053 0.019 0.0417
Onchocerca volvulus 0.0038 0.0118 0.038
Schistosoma mansoni Smad4 0.0016 0.001 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0976 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0053 0.0422
Schistosoma mansoni survival motor neuron protein 0.0055 0.0198 0.0434
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0016 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Onchocerca volvulus 0.004 0.0126 0.0409
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.026 0.026
Echinococcus multilocularis neuropeptide receptor A26 0.0532 0.2514 0.2514
Mycobacterium tuberculosis Conserved protein 0.0038 0.0118 0.0779
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0007 0.0022
Echinococcus multilocularis fibrillin 1 0.0016 0.001 0.001
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0034 0.0117
Schistosoma mansoni hypothetical protein 0.0195 0.0879 0.193
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Loa Loa (eye worm) growth/differentiation factor 10 0.0016 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0143 0.0501
Loa Loa (eye worm) hypothetical protein 0.0025 0.0053 0.0184
Schistosoma mansoni cellular tumor antigen P53 0.0304 0.1407 0.3089
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0034 0.0033
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0095 0.0392 0.0861
Brugia malayi Fibroblast growth factor family protein 0.006 0.0225 0.0784
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.017 0.0595
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0215 0.0976 0.0976
Trichomonas vaginalis set domain proteins, putative 0.0511 0.2412 0.8422
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0035
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.001 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0035 0.0035
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0215 0.0976 0.0976
Chlamydia trachomatis DNA topoisomerase I 0.0605 0.2864 0.5
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0288 0.0288
Entamoeba histolytica hypothetical protein 0.0073 0.0288 0.7208
Echinococcus granulosus zinc finger protein Ran binding 0.0215 0.0976 0.0976
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0034 0.0223
Brugia malayi hypothetical protein 0.0073 0.0288 0.1005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Leishmania major hypothetical protein, conserved 0.0215 0.0976 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0272 1
Echinococcus multilocularis microtubule associated protein 2 0.0676 0.3209 0.3208
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0045 0.0157
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0288 0.0632
Plasmodium falciparum cysteine repeat modular protein 1 0.004 0.0126 0.0325
Echinococcus multilocularis lamin 0.003 0.0077 0.0077
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.011 0.011
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0034 0.0369
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0031
Leishmania major hypothetical protein, conserved 0.0215 0.0976 1
Schistosoma mansoni zinc finger protein 0.0016 0.0012 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0298 0.104
Brugia malayi CXXC zinc finger family protein 0.0067 0.0258 0.0899
Schistosoma mansoni lipoxygenase 0.0021 0.0035 0.0077
Echinococcus granulosus intermediate filament protein 0.003 0.0077 0.0077
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0034 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.0631
Brugia malayi Unc-6 protein precursor 0.0023 0.0043 0.0149
Toxoplasma gondii kringle domain-containing protein 0.004 0.0126 0.0405
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0035
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0021 0.0021
Schistosoma mansoni cpg binding protein 0.0067 0.0258 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Echinococcus multilocularis dnaJ subfamily B 0.0953 0.4554 0.4554
Loa Loa (eye worm) CXXC zinc finger family protein 0.0067 0.0258 0.0899
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0156 0.1491
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0118 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Schistosoma mansoni hypothetical protein 0.0215 0.0976 0.2142
Mycobacterium tuberculosis Conserved protein 0.0038 0.0118 0.0779
Onchocerca volvulus 0.0066 0.0252 0.085
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0272 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0068 0.0068
Trichomonas vaginalis esterase, putative 0.0038 0.0118 0.041
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0068 0.0149
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.041
Loa Loa (eye worm) hypothetical protein 0.0029 0.0075 0.026
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0207 0.0723
Trichomonas vaginalis helicase, putative 0.0015 0.0007 0.0022
Echinococcus granulosus laminin 0.0016 0.001 0.001
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0215 0.0976 0.3406
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0053 0.0186
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.017 0.0374
Echinococcus granulosus lamin dm0 0.003 0.0077 0.0077
Echinococcus granulosus histone lysine methyltransferase setb 0.0084 0.034 0.034
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0087 0.0777
Schistosoma mansoni hypothetical protein 0.0073 0.0288 0.0632
Loa Loa (eye worm) latrophilin receptor protein 2 0.0053 0.019 0.0664
Echinococcus multilocularis Smad4 0.0016 0.001 0.001
Echinococcus multilocularis GPCR, family 2 0.0053 0.019 0.019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0084 0.034 0.034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0084 0.034 0.0746
Loa Loa (eye worm) hypothetical protein 0.0046 0.0156 0.0544
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0215 0.0976 0.3406
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0118 0.0779
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Loa Loa (eye worm) hypothetical protein 0.0304 0.1407 0.4911
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0215 0.0976 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0156 0.0156
Toxoplasma gondii FATC domain-containing protein 0.0018 0.002 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.002 0.0069
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0118 0.0117
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0156 0.0156
Echinococcus multilocularis cpg binding protein 0.0073 0.0286 0.0286
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0156 0.0156
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0077 0.027
Onchocerca volvulus 0.0021 0.0035 0.0093
Mycobacterium ulcerans lipase LipD 0.0038 0.0118 0.3519
Echinococcus granulosus tissue type plasminogen activator 0.004 0.0126 0.0126
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.002 0.002
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0118 0.3519
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0156 0.1491
Loa Loa (eye worm) hypothetical protein 0.006 0.0225 0.0785
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0605 0.2864 1
Brugia malayi beta-lactamase family protein 0.0038 0.0118 0.041
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0035 0.0124
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.002 0.0081
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0025 0.0025
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0053 0.019 0.019
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0053 0.0068
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0215 0.0976 1
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0035
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0095 0.0392 0.3943
Schistosoma mansoni smad 0.0016 0.001 0.0022
Echinococcus granulosus SWI:SNF matrix associated 0.0605 0.2864 0.2864
Brugia malayi Pre-SET motif family protein 0.0066 0.0252 0.0878
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0118 0.3519
Echinococcus multilocularis RUN 0.0021 0.0035 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.017 0.017
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0053 0.019 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0231 0.0806
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Echinococcus granulosus tgf beta family 0.0016 0.0009 0.0009
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0016 0.001 0.0035
Schistosoma mansoni rab6-interacting 0.0021 0.0035 0.0077
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.1111 1
Echinococcus granulosus cpg binding protein 0.0073 0.0286 0.0286
Brugia malayi hypothetical protein 0.0504 0.2375 0.8293
Schistosoma mansoni hypothetical protein 0.0022 0.004 0.0087
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0215 0.0976 0.3328
Echinococcus multilocularis neuropeptide s receptor 0.0532 0.2514 0.2514
Entamoeba histolytica hypothetical protein 0.0073 0.0288 0.7208
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0156 0.0342
Schistosoma mansoni ap endonuclease 0.0021 0.0034 0.0073
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0098 0.0342
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0034 0.0223
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0215 0.0976 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0053 0.019 0.019
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0045 0.0045
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0118 0.041
Brugia malayi beta-lactamase 0.0038 0.0118 0.041
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0021 0.0021
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0003 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0118 0.1094
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0215 0.0976 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0118 0.0779
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.0392 0.1369
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0118 0.0779
Onchocerca volvulus Huntingtin homolog 0.0144 0.0633 0.2186
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0095 0.0392 0.3943
Schistosoma mansoni hypothetical protein 0.0605 0.2864 0.6289
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0118 0.041
Mycobacterium ulcerans hypothetical protein 0.0038 0.0118 0.3519
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0126 0.0276
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0053 0.0422
Mycobacterium tuberculosis Conserved protein 0.0038 0.0118 0.0779
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0303
Schistosoma mansoni hypothetical protein 0.0055 0.0198 0.0434
Brugia malayi brahma associated protein 60 kDa 0.0605 0.2864 1
Loa Loa (eye worm) hypothetical protein 0.0215 0.0976 0.3407
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0087 0.0777
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.001 0.001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0118 0.0117
Leishmania major hypothetical protein, conserved 0.0215 0.0976 1
Loa Loa (eye worm) beta-lactamase 0.0038 0.0118 0.041
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0035 0.0006
Onchocerca volvulus 0.003 0.0077 0.0239
Brugia malayi hypothetical protein 0.0021 0.0035 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0392 0.1368
Onchocerca volvulus 0.0021 0.0035 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0298 0.104
Loa Loa (eye worm) TK/ROR protein kinase 0.0044 0.0146 0.0509
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0131 0.0458
Echinococcus granulosus serine protein kinase ATM 0.0018 0.002 0.002
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0233 0.0233
Echinococcus multilocularis tissue type plasminogen activator 0.004 0.0126 0.0126
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0039 0.0124 0.1158
Echinococcus granulosus GPCR family 2 0.0053 0.019 0.019
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0053 0.0068
Leishmania major hypothetical protein, conserved 0.0215 0.0976 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0664
Brugia malayi Doublecortin family protein 0.0021 0.0035 0.0123
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.001 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0156 0.0543
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0098 0.0342
Echinococcus granulosus netrin 1 0.0023 0.0043 0.0043
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.0392 0.1368
Mycobacterium leprae Probable lipase LipE 0.0038 0.0118 0.5
Echinococcus multilocularis ring and YY1 binding protein 0.0215 0.0976 0.0976
Echinococcus multilocularis netrin 1 0.0023 0.0043 0.0043
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0021 0.0046
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0016 0.001 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0118 0.0296
Schistosoma mansoni RNA binding protein 0.0215 0.0976 0.2142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0303
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0118 0.0779
Loa Loa (eye worm) hypothetical protein 0.0215 0.0976 0.3407
Loa Loa (eye worm) hypothetical protein 0.0144 0.0633 0.2211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0241 0.0841
Echinococcus granulosus Zinc finger RanBP2 type 0.0215 0.0976 0.0976
Echinococcus granulosus bone morphogenetic protein 2 0.0016 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0066 0.0252 0.0252
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0119 0.0118
Toxoplasma gondii histone lysine methyltransferase SET1 0.0132 0.0571 0.1967
Schistosoma mansoni hypothetical protein 0.0605 0.2864 0.6289
Leishmania major hypothetical protein, conserved 0.0215 0.0976 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0274 0.0958
Schistosoma mansoni zinc finger protein 0.0025 0.0053 0.0115
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0016 0.001 0.0035
Echinococcus multilocularis tgf beta family 0.0016 0.0009 0.0009
Echinococcus granulosus neuropeptide s receptor 0.0532 0.2514 0.2514
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Schistosoma mansoni hypothetical protein 0.0605 0.2864 0.6289
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0061 0.023 0.023
Onchocerca volvulus 0.0055 0.0198 0.0661
Schistosoma mansoni TRABID protein (C64 family) 0.0215 0.0976 0.2142
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.001 0.0022
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0095 0.0392 0.3943
Echinococcus multilocularis Tolloid protein 1 0.0016 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0298 0.104
Entamoeba histolytica hypothetical protein 0.0073 0.0288 0.7208
Loa Loa (eye worm) hypothetical protein 0.0084 0.034 0.1186
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0045 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0976 1
Schistosoma mansoni zinc finger protein 0.0215 0.0976 0.2142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.041
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.001 0.0035
Mycobacterium ulcerans beta-lactamase 0.0038 0.0118 0.3519
Loa Loa (eye worm) hypothetical protein 0.0075 0.0298 0.1042
Onchocerca volvulus 0.0605 0.2864 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0215 0.0976 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0035
Onchocerca volvulus 0.0215 0.0976 0.3386
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0156 0.0156
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0156 0.1491
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0156 0.0156
Onchocerca volvulus Huntingtin homolog 0.0144 0.0633 0.2186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0298 0.104
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0272 0.0918
Brugia malayi Transforming growth factor beta like domain containing protein 0.0061 0.023 0.0802
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0025 0.0025
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0035 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.011 0.011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.002 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0056 0.0196
Schistosoma mansoni ap endonuclease 0.0021 0.0034 0.0073
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.0252 0.0552
Onchocerca volvulus 0.0038 0.0118 0.038
Schistosoma mansoni hypothetical protein 0.0053 0.019 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.002 0.003 0.0103
Echinococcus granulosus ring and YY1 binding protein 0.0215 0.0976 0.0976
Brugia malayi Latrophilin receptor protein 2 0.0053 0.019 0.0663
Echinococcus granulosus survival motor neuron protein 1 0.0268 0.1231 0.1231
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.001 0.0036
Echinococcus multilocularis laminin 0.0016 0.001 0.001
Schistosoma mansoni netrin 0.0023 0.0043 0.0094
Brugia malayi Smad1 0.0016 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.041
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0087 0.0087
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0034 0.0033
Chlamydia trachomatis SWIB complex protein 0.0605 0.2864 0.5
Echinococcus granulosus smad 0.0016 0.001 0.001
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.004 0.0138
Loa Loa (eye worm) LjBmp2/4b 0.0016 0.0009 0.0031
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0156 0.0156
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0118 0.041
Brugia malayi intermediate filament protein 0.003 0.0077 0.0269
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0198 0.069
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0018 0.002 0.0081
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0215 0.0976 0.0976
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0068 0.0068
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0215 0.0976 0.3383
Brugia malayi beta-lactamase family protein 0.0038 0.0118 0.041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.017 0.0374
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0605 0.2864 1
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0034 0.0117
Loa Loa (eye worm) hypothetical protein 0.006 0.0225 0.0785
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0392 0.1368
Schistosoma mansoni bromodomain containing protein 0.0071 0.0278 0.0611
Schistosoma mansoni brg-1 associated factor 0.0605 0.2864 0.6289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.0631
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0061 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0215 0.0976 0.3407
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0272 0.0597
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.011 0.0383
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0126 0.1179
Schistosoma mansoni lipoxygenase 0.0059 0.022 0.0482
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0272 1
Echinococcus multilocularis musashi 0.003 0.0077 0.0077
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0018 0.002 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0025 0.0055
Schistosoma mansoni lamin 0.003 0.0077 0.0169
Brugia malayi Calcitonin receptor-like protein seb-1 0.0168 0.0745 0.2602
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0022
Onchocerca volvulus 0.0215 0.0976 0.3386
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.017 0.017
Entamoeba histolytica hypothetical protein 0.0073 0.0288 0.7208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0303
Loa Loa (eye worm) intermediate filament protein 0.003 0.0077 0.027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0084 0.034 0.0746
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0181 0.063
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.011 0.0383
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0022
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0053 0.0068
Loa Loa (eye worm) hypothetical protein 0.0504 0.2375 0.8293
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0325 0.1134
Echinococcus multilocularis serine protein kinase ATM 0.0018 0.002 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0272 0.0597
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0087 0.0777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0205 0.0714
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0272 0.2697
Onchocerca volvulus 0.0038 0.0118 0.038
Schistosoma mansoni intermediate filament proteins 0.003 0.0077 0.0169
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0605 0.2864 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.041
Brugia malayi brahma associated protein 60 kDa 0.0605 0.2864 1
Brugia malayi hypothetical protein 0.0016 0.0009 0.0031
Brugia malayi Bromodomain containing protein 0.0041 0.0131 0.0456
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0075 0.0299 0.2972
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0087 0.0304
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.017 0.0595
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0095 0.0392 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0298 0.104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0093
Brugia malayi Pre-SET motif family protein 0.0449 0.2112 0.7374
Loa Loa (eye worm) hypothetical protein 0.0168 0.0745 0.2602
Echinococcus granulosus lamin 0.003 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.003 0.0077 0.027
Echinococcus multilocularis smad 0.0016 0.001 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0288 0.0288
Echinococcus multilocularis SWI:SNF matrix associated 0.0605 0.2864 0.2864
Echinococcus multilocularis SWI:SNF matrix associated 0.0605 0.2864 0.2864
Schistosoma mansoni cpg binding protein 0.0073 0.0286 0.0627
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.022 0.0219
Brugia malayi MH2 domain containing protein 0.0234 0.1066 0.3723
Trypanosoma brucei hypothetical protein, conserved 0.0215 0.0976 1
Brugia malayi Transforming growth factor beta like domain containing protein 0.0016 0.0009 0.0031
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0605 0.2864 0.2864
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0031
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0034 0.5
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0024 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0449 0.2112 0.7375
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0003 0.0002
Echinococcus granulosus neuropeptide receptor A26 0.0532 0.2514 0.2514
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0215 0.0976 0.3406
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0022
Schistosoma mansoni cpg binding protein 0.0073 0.0286 0.0627
Schistosoma mansoni hypothetical protein 0.0053 0.019 0.0417
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0302
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0605 0.2864 1
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.001 0.0035
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0077 0.0269
Schistosoma mansoni rab6-interacting 0.0021 0.0035 0.0077
Schistosoma mansoni tgf-beta family 0.0016 0.0009 0.0019
Onchocerca volvulus 0.0511 0.2412 0.8417
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0168 0.0745 0.2602
Onchocerca volvulus Arrow homolog 0.0016 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0115 0.0488 0.1705
Schistosoma mansoni polycystin 1-related 0.0021 0.0035 0.0077
Brugia malayi latrophilin 2 splice variant baaae 0.0115 0.0488 0.1705
Echinococcus multilocularis tumor protein p63 0.2077 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0066 0.0252 0.0846
Loa Loa (eye worm) hypothetical protein 0.0144 0.0633 0.2211
Loa Loa (eye worm) hypothetical protein 0.0215 0.0976 0.3407
Echinococcus multilocularis geminin 0.0195 0.0879 0.0879
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0035
Loa Loa (eye worm) hypothetical protein 0.0049 0.0172 0.06
Brugia malayi Transforming growth factor beta like domain containing protein 0.0016 0.0009 0.0031
Toxoplasma gondii target of rapamycin (TOR), putative 0.007 0.0274 0.0926
Schistosoma mansoni hypothetical protein 0.004 0.0126 0.0276
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0007 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0118 0.5
Brugia malayi hypothetical protein 0.0144 0.0633 0.221
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0119 0.0118
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0095 0.0392 0.3943
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.041
Brugia malayi SWIB/MDM2 domain containing protein 0.0605 0.2864 1
Brugia malayi hypothetical protein 0.0016 0.0009 0.0031
Onchocerca volvulus 0.003 0.0081 0.0252
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0118 0.041
Loa Loa (eye worm) hypothetical protein 0.0215 0.0976 0.3407
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.001 0.001
Brugia malayi YY1-associated factor 2 0.0215 0.0976 0.3406
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.002 0.002
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0035 0.0035
Brugia malayi Protein kinase domain containing protein 0.0044 0.0146 0.0509
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0034 0.0117
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0035 0.0035
Brugia malayi Kringle domain containing protein 0.004 0.0126 0.0438
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0272 0.2212
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0118 0.1094
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0144 0.0633 0.1389
Brugia malayi hypothetical protein 0.0268 0.1231 0.4297
Leishmania major hypothetical protein, conserved 0.004 0.0126 0.1179
Schistosoma mansoni hypothetical protein 0.0115 0.0488 0.1072
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0034 0.0223
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0016 0.001 0.0022
Toxoplasma gondii ran binding protein 0.0215 0.0976 0.3383
Echinococcus granulosus dnaJ subfamily B 0.0953 0.4554 0.4554
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.001 0.0036
Echinococcus granulosus Tolloid protein 1 0.0016 0.001 0.001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0272 0.0272
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0605 0.2864 0.2864
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0069
Loa Loa (eye worm) Smad1 0.0016 0.001 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0118 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0207 0.0723
Toxoplasma gondii ABC1 family protein 0.0038 0.0118 0.0376

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Antimycobacterial activity of the compound was evaluated against Mycobacterium smegmatis; Active ChEMBL. 11425536

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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