Detailed information for compound 659139

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.527 | Formula: C26H29N3O2
  • H donors: 2 H acceptors: 3 LogP: 3.98 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)C1C(=C(C)N=C2C1=C(O)CC(C2)(C)C)C(=O)Nc1nccc(c1)C
  • InChi: 1S/C26H29N3O2/c1-15-6-8-18(9-7-15)23-22(25(31)29-21-12-16(2)10-11-27-21)17(3)28-19-13-26(4,5)14-20(30)24(19)23/h6-12,23,30H,13-14H2,1-5H3,(H,27,29,31)
  • InChiKey: KYBAWLAKGKINFC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0182 0.0182
Echinococcus multilocularis lysine specific demethylase 6a 0.001 0.0073 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0637 0.0637
Loa Loa (eye worm) RasGEF domain-containing protein 0.0006 0.0002 0.0002
Loa Loa (eye worm) sugar transporter 0.0109 0.2222 0.2222
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0762 0.0773
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0662 0.0662
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0393 0.4516
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0117 0.1769
Brugia malayi RasGEF domain containing protein 0.0006 0.0002 0.0002
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0006 0.0002 0.0003
Schistosoma mansoni protein phosphatase 2C 0.001 0.0073 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0109 0.2222 0.3114
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0662 0.9578
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0267 0.386
Entamoeba histolytica hypothetical protein 0.0036 0.0649 0.3384
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0762 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0199 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.1919 0.1919
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0662 0.0927
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0833 0.0833
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0833 0.1167
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0034 0.0589 0.0597
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0662 0.1339
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0353 0.0358
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0057 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0073 0.0073
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.28 0.28
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0141 0.2126
Schistosoma mansoni importin beta-1 0.0031 0.0528 0.0739
Echinococcus granulosus serotonin transporter 0.0275 0.5776 0.5776
Leishmania major hypothetical protein, conserved 0.0037 0.0662 0.9578
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.3187 0.3187
Schistosoma mansoni hypothetical protein 0.0039 0.0716 0.1004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.0598 0.8651
Toxoplasma gondii thioredoxin reductase 0.0037 0.0656 0.1006
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.1951 0.2733
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0047 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0073
Brugia malayi AF-10 protein 0.001 0.0075 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.013 0.013
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0034 0.0589 0.0589
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.087
Schistosoma mansoni ras GTP exchange factor 0.0006 0.0002 0.0003
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.087 0.122
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0034 0.0589 0.0589
Entamoeba histolytica Ran family GTPase 0.0023 0.0353 0.1842
Brugia malayi N-terminal motif family protein 0.0179 0.3714 0.3714
Giardia lamblia Sugar-proton symporter 0.0015 0.0199 0.2606
Schistosoma mansoni dep domain containing protein 0.0009 0.0057 0.008
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0844 0.1675
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0662 0.3546
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Onchocerca volvulus 0.0047 0.087 0.1503
Brugia malayi beta-lactamase 0.0037 0.0662 0.0662
Plasmodium falciparum hexose transporter 0.0109 0.2222 0.2253
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0637 0.0893
Schistosoma mansoni jumonji domain containing protein 0.0077 0.1523 0.2133
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0691 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Trichomonas vaginalis ras GTP exchange factor, putative 0.0006 0.0002 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0666 0.0666
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0691 1
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0199 0.2874
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.001 0.0073 0.1054
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0504 0.0504
Trichomonas vaginalis sugar transporter, putative 0.0034 0.0598 0.1187
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0057 0.008
Loa Loa (eye worm) hypothetical protein 0.0095 0.1919 0.1919
Brugia malayi hypothetical protein 0.0018 0.0258 0.0258
Treponema pallidum sodium- and chloride- dependent transporter 0.0275 0.5776 1
Schistosoma mansoni dishevelled 0.0009 0.0057 0.008
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0117 0.0203
Onchocerca volvulus 0.0015 0.0199 0.034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0833 0.1167
Loa Loa (eye worm) hypothetical protein 0.0028 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0141 0.2036
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0057 0.008
Brugia malayi RasGEF domain containing protein 0.0006 0.0002 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0073 0.0073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Schistosoma mansoni sodium/chloride dependent transporter 0.0049 0.0916 0.1283
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0393 0.0393
Brugia malayi PHD-finger family protein 0.001 0.0075 0.0075
Schistosoma mansoni patched 1 0.0041 0.0748 0.1048
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0528 0.0809
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) sugar transporter 0.0015 0.0199 0.0199
Schistosoma mansoni hypothetical protein 0.0013 0.0139 0.0195
Brugia malayi jmjC domain containing protein 0.001 0.0073 0.0073
Entamoeba histolytica hypothetical protein 0.0006 0.0002 0.0013
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.013 0.0182
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0662 0.1314
Schistosoma mansoni thyroid hormone receptor 0.0012 0.013 0.0182
Mycobacterium leprae Probable lipase LipE 0.0037 0.0662 0.3546
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0057 0.0057
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0034 0.0589 0.0589
Brugia malayi hypothetical protein 0.0015 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0027 0.0454 0.0454
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0057 0.0057
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Trypanosoma cruzi hexose transporter 0.0034 0.0598 0.8651
Onchocerca volvulus 0.0027 0.0454 0.0781
Onchocerca volvulus 0.0015 0.0199 0.034
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0393 0.0399
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.1951 0.1951
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.013 0.013
Plasmodium falciparum amino acid transporter, putative 0.0047 0.087 0.0883
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0662 0.1314
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0662 0.0662
Echinococcus granulosus son of sevenless 1 0.0006 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.1934 0.1934
Brugia malayi hypothetical protein 0.0015 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.087 0.122
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0662 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0109 0.2222 0.2222
Schistosoma mansoni hypothetical protein 0.0039 0.0716 0.1004
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0009 0.0057 0.0094
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0196 0.0196
Echinococcus multilocularis lamin dm0 0.0027 0.0454 0.0454
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0314 0.1682
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0015 0.0196 0.0275
Echinococcus multilocularis protein dispatched 1 0.0047 0.0872 0.0872
Brugia malayi jmjC domain containing protein 0.001 0.0073 0.0073
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0403 0.08
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.0048 0.0906 0.0906
Schistosoma mansoni glucose transport protein 0.0109 0.2222 0.3114
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0141 0.2036
Echinococcus granulosus FTZ F1 alpha 0.0012 0.013 0.013
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0196 0.0196
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0141 0.0197
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.087
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0057 0.0057
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0006 0.0002 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0199 0.0201
Schistosoma mansoni hypothetical protein 0.0039 0.0716 0.1004
Plasmodium falciparum mitogen-activated protein kinase 2 0.0177 0.3673 0.3724
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Brugia malayi Thioredoxin reductase 0.0037 0.0656 0.0656
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0662 0.1339
Schistosoma mansoni nuclear hormone receptor 0.0012 0.013 0.0182
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0033 0.0574 0.0574
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0006 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.2222 0.4413
Loa Loa (eye worm) hypothetical protein 0.0148 0.305 0.305
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0353 0.5115
Echinococcus granulosus survival motor neuron protein 1 0.0471 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.013 0.0182
Schistosoma mansoni hypothetical protein 0.0338 0.7138 1
Echinococcus multilocularis muscleblind protein 0.0148 0.305 0.305
Brugia malayi N-terminal motif family protein 0.0006 0.0002 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0656 0.0665
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0006 0.0009
Leishmania major protein kinase, putative 0.0034 0.0589 0.8517
Schistosoma mansoni hypothetical protein 0.001 0.0075 0.0106
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.013 0.013
Toxoplasma gondii sugar transporter ST2 0.0015 0.0199 0.0305
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.1666 0.337
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0141 0.2036
Toxoplasma gondii hypothetical protein 0.0009 0.0057 0.0087
Echinococcus granulosus JmjC domain containing protein 4 0.001 0.0073 0.0073
Schistosoma mansoni coup transcription factor 0.0012 0.013 0.0182
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.1666 0.337
Onchocerca volvulus Alhambra homolog 0.003 0.0504 0.0868
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0141 0.2036
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0393 0.0393
Plasmodium vivax calcium-dependent protein kinase, putative 0.0034 0.0589 0.0597
Brugia malayi Sugar transporter family protein 0.0109 0.2222 0.2222
Brugia malayi RasGEF domain containing protein 0.0006 0.0002 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.4943 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.087 0.122
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0393 0.5689
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0199 0.3001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0662 0.0662
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.087 0.087
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0033 0.0574 0.3075
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0393 0.5689
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.4409 0.4409
Trichomonas vaginalis glucose transporter, putative 0.0034 0.0598 0.1187
Onchocerca volvulus 0.0015 0.0199 0.034
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.1867 0.3776
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0034 0.0589 0.0597
Plasmodium vivax hexose transporter 0.0109 0.2222 0.2253
Echinococcus multilocularis serotonin transporter 0.0275 0.5776 0.5776
Echinococcus granulosus muscleblind protein 0.0148 0.305 0.305
Onchocerca volvulus 0.0047 0.087 0.1503
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.087
Echinococcus granulosus Protein son of sevenless 0.0006 0.0002 0.0002
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Plasmodium falciparum calcium-dependent protein kinase 2 0.0034 0.0589 0.0597
Leishmania major glucose transporter, lmgt2 0.0034 0.0598 0.8651
Plasmodium vivax sugar transporter, putative 0.0015 0.0199 0.0201
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0199 0.0199
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0057 0.0057
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0662 0.1339
Loa Loa (eye worm) hypothetical protein 0.0027 0.0443 0.0443
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0649 0.0649
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0141 0.0141
Brugia malayi CHE-14 protein 0.0041 0.0748 0.0748
Echinococcus granulosus lysine specific demethylase 6a 0.001 0.0073 0.0073
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0141 0.1846
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0073 0.0073
Plasmodium falciparum glutathione reductase 0.0037 0.0656 0.0665
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.013 0.013
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0199 0.0199
Brugia malayi steroid hormone receptor 0.0012 0.013 0.013
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0033 0.0574 0.2991
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Schistosoma mansoni hypothetical protein 0.0033 0.0578 0.0809
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.014 0.014
Echinococcus granulosus geminin 0.0338 0.7138 0.7138
Brugia malayi Muscleblind-like protein 0.0148 0.305 0.305
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0199 0.0394
Schistosoma mansoni hypothetical protein 0.0338 0.7138 1
Loa Loa (eye worm) glutathione reductase 0.0037 0.0656 0.0656
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.013 0.0182
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0353 0.5115
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0033 0.0574 0.0574
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0528 0.0528
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0598 0.8651
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0473 0.048
Onchocerca volvulus 0.0037 0.0662 0.1142
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Onchocerca volvulus 0.0012 0.013 0.0221
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.0598 0.8651
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0598 0.1187
Echinococcus granulosus jumonji domain containing 1A 0.001 0.0073 0.0073
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0844 0.0855
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0662 0.9578
Onchocerca volvulus 0.0015 0.0199 0.034
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0519 0.0519
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0473 0.048
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.169 0.8804
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.1919 0.1919
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.001 0.0073 0.0073
Echinococcus granulosus phd:f box containing protein 0.001 0.0073 0.0073
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0314 0.0635
Loa Loa (eye worm) hypothetical protein 0.0013 0.014 0.014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0519 0.0727
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.013 0.013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0141 0.2036
Leishmania major trypanothione reductase 0.0037 0.0656 0.9491
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Trichomonas vaginalis set domain proteins, putative 0.024 0.5036 1
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0662 0.1339
Loa Loa (eye worm) beta-lactamase 0.0037 0.0662 0.0662
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0057 0.0057
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0504 0.0706
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0141 0.2036
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0314 0.0635
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0005
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0199 0.0305
Brugia malayi Sugar transporter family protein 0.0015 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.005 0.0946 0.0946
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0117 0.1345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0009 0.0068 0.0068
Echinococcus granulosus snurportin 1 0.0328 0.6916 0.6916
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0504 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.013 0.013
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0141 0.0216
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.013 0.013
Onchocerca volvulus 0.0037 0.0662 0.1142
Entamoeba histolytica hypothetical protein 0.0036 0.0649 0.3384
Plasmodium vivax hypothetical protein, conserved 0.0047 0.087 0.0883
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0038 0.0691 0.106
Echinococcus granulosus peregrin 0.0033 0.0585 0.0585
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0141 0.0279
Loa Loa (eye worm) hypothetical protein 0.0024 0.0393 0.0393
Echinococcus granulosus importin subunit beta 1 0.0031 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0033 0.0578 0.0578
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0141 0.2036
Loa Loa (eye worm) RasGEF domain-containing protein 0.0006 0.0002 0.0002
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.28 0.28
Brugia malayi hypothetical protein 0.0009 0.0057 0.0057
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0075 0.0116
Schistosoma mansoni protein kinase 0.0034 0.0589 0.0825
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0141 0.7084
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.013 0.0182
Brugia malayi Cam kinase protein 1 0.0034 0.0589 0.0589
Schistosoma mansoni glucose transporter 0.0015 0.0199 0.0278
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0199 0.0199
Echinococcus multilocularis phd:f box containing protein 0.001 0.0073 0.0073
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0403 0.5831
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0454 0.0454
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0047 0.087 0.087
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0691 1
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0199 0.0402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0442 0.0442
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0598 0.8651
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0519 0.0727
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0141 0.0216
Echinococcus multilocularis expressed conserved protein 0.009 0.1795 0.1795
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.087
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.1867 0.3776
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0906 0.0906
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0141 0.0143
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0473 0.6846
Schistosoma mansoni sugar transporter 0.0015 0.0199 0.0278
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0196 0.0196
Plasmodium falciparum glutathione reductase 0.0013 0.0141 0.0143
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0196 0.0196
Onchocerca volvulus 0.0009 0.0057 0.0094
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.013 0.013
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.087 0.122
Loa Loa (eye worm) hypothetical protein 0.0275 0.5776 0.5776
Mycobacterium tuberculosis Conserved protein 0.0037 0.0662 0.1339
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.1919 0.1919
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0393 0.0393
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0073 0.1054
Brugia malayi RNA, U transporter 1 0.0087 0.1745 0.1745
Plasmodium falciparum proline--tRNA ligase 0.0038 0.0691 0.0701
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0199 0.0199
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0006 0.0002 0.0002
Loa Loa (eye worm) serotonin transporter b 0.0275 0.5776 0.5776
Schistosoma mansoni protein kinase 0.0034 0.0589 0.0825
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.013 0.013
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0057 0.008
Echinococcus multilocularis survival motor neuron protein 1 0.0471 1 1
Schistosoma mansoni hypothetical protein 0.0039 0.0716 0.1004
Brugia malayi nuclear hormone receptor 0.0012 0.013 0.013
Trypanosoma brucei trypanothione reductase 0.0037 0.0656 0.9491
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0393 0.0781
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0393 0.0551
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0177 0.3673 0.5632
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0199 1
Onchocerca volvulus 0.0015 0.0199 0.034
Schistosoma mansoni thyroid hormone receptor 0.0012 0.013 0.0182
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0006 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0013 0.015 0.015
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0844 0.1294
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0649 0.091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.013 0.013
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.013 0.013
Echinococcus multilocularis peregrin 0.0033 0.0585 0.0585
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.001 0.0075 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.013 0.013
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0141 0.2126
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0196 0.0196
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.013 0.013
Echinococcus multilocularis son of sevenless 1 0.0006 0.0002 0.0002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Trichomonas vaginalis esterase, putative 0.0037 0.0662 0.1314
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0075 0.1092
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0504 0.0772
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0275 0.5776 0.5776
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0047 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0006
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.087 0.087
Echinococcus granulosus lamin dm0 0.0027 0.0454 0.0454
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.013 0.013
Onchocerca volvulus 0.0015 0.0199 0.034
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0141 0.0285
Plasmodium falciparum transporter, putative 0.0047 0.087 0.0883
Schistosoma mansoni ran 0.0023 0.0353 0.0495
Onchocerca volvulus 0.0015 0.0199 0.034
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0753 0.0753
Onchocerca volvulus 0.0015 0.0199 0.034
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0006 0.0002 0.0003
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0057 0.0057
Loa Loa (eye worm) solute carrier family 6 member 4 0.0275 0.5776 0.5776
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0047 0.087 0.087
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Schistosoma mansoni hypothetical protein 0.0036 0.0649 0.091
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0006 0.0006
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0139 0.0139
Schistosoma mansoni phd/f-box containing protein 0.001 0.0073 0.0102
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.001 0.0073 0.0073
Brugia malayi jmjC domain containing protein 0.0097 0.1951 0.1951
Onchocerca volvulus 0.024 0.5036 0.8718
Brugia malayi hypothetical protein 0.0047 0.087 0.087
Brugia malayi ecdysteroid receptor 0.0012 0.013 0.013
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0598 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.0179 0.3714 0.3714
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0589 0.0825
Plasmodium vivax amine transporter, putative 0.0047 0.087 0.0883
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0057 0.0057
Plasmodium falciparum importin beta, putative 0.0031 0.0528 0.0535
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.001 0.0073 0.0112
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0034 0.0589 0.0903
Brugia malayi jmjC domain containing protein 0.001 0.0073 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Plasmodium falciparum phd finger protein, putative 0.003 0.0504 0.0511
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.169 0.8804
Brugia malayi jmjC domain containing protein 0.001 0.0073 0.0073
Echinococcus multilocularis JmjC domain containing protein 4 0.001 0.0073 0.0073
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0199 0.2874
Loa Loa (eye worm) hypothetical protein 0.001 0.0075 0.0075
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0662 0.1339
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.3187 0.4464
Echinococcus multilocularis General substrate transporter 0.0094 0.1891 0.1891
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Toxoplasma gondii sugar transporter ST3 0.0015 0.0199 0.0305
Echinococcus multilocularis solute carrier family 22 0.0015 0.0199 0.0199
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0141 0.2036
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0353 0.0542
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0141 0.0143
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0662 0.1314
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0199 0.0394
Entamoeba histolytica protein kinase, putative 0.0034 0.0589 0.3067
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0047 0.087 0.087
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0637 0.0637
Loa Loa (eye worm) norepinephrine transporter 0.0275 0.5776 0.5776
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Plasmodium vivax glutathione reductase, putative 0.0037 0.0656 0.0665
Leishmania major glucose transporter, lmgt3 0.0034 0.0598 0.8651
Leishmania major GTP-binding protein, putative 0.0023 0.0353 0.5115
Schistosoma mansoni intermediate filament proteins 0.0027 0.0454 0.0636
Mycobacterium ulcerans sugar transporter 0.0015 0.0199 0.3001
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0141 0.0279
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0073
Echinococcus granulosus GPCR family 2 0.0015 0.0196 0.0196
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0656 0.9491
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0199 0.0394
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0662 0.9578
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.087 0.087
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.087 0.122
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0353 0.5115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.013 0.013
Toxoplasma gondii ABC1 family protein 0.0037 0.0662 0.1015
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.1335
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.013 0.013
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0748 0.0748
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0057 0.0057
Schistosoma mansoni sugar transporter 0.0015 0.0199 0.0278
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.3187 0.3187
Onchocerca volvulus 0.0015 0.0199 0.034
Schistosoma mansoni hypothetical protein 0.003 0.0504 0.0706
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0393 0.5689
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.013 0.013
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0649 0.0649
Toxoplasma gondii hypothetical protein 0.0047 0.087 0.1335
Plasmodium vivax proline--tRNA ligase, putative 0.0038 0.0691 0.0701
Echinococcus multilocularis solute carrier family 22 0.0015 0.0199 0.0199
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0691 1
Schistosoma mansoni glucose transport protein 0.0109 0.2222 0.3114
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0073 0.1054
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.015 0.015
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0034 0.0589 0.0589
Entamoeba histolytica hypothetical protein 0.0036 0.0649 0.3384
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0544 0.0544
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0006 0.0006 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0662 0.1314
Brugia malayi jmjC domain containing protein 0.0036 0.0637 0.0637
Toxoplasma gondii sugar transporter ST1 0.0015 0.0199 0.0305
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.3093 0.3093
Leishmania major glucose transporter, lmgt1 0.0034 0.0598 0.8651
Brugia malayi hypothetical protein 0.0009 0.0057 0.0057
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0454 0.0454
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0403 0.08
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.013 0.013
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0008 0.0037 0.0541
Brugia malayi intermediate filament protein 0.0027 0.0454 0.0454
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0199 0.2874
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0199 0.0394
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0519 0.0727
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0199 0.3001
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0047 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.0037 0.0662 0.0662
Echinococcus multilocularis musashi 0.0027 0.0454 0.0454
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0393 0.5158
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0753 0.0753
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.013 0.013
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.1181 0.1181
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0034 0.0589 0.0903
Plasmodium vivax JmjC domain containing protein 0.001 0.0073 0.0074
Echinococcus multilocularis GPCR, family 2 0.0015 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.0015 0.0196 0.0275
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.013 0.013
Onchocerca volvulus 0.0015 0.0199 0.034
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.013 0.013
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.1867 0.3776
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0662 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.013 0.013
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0199 0.0394
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.013 0.0182
Schistosoma mansoni dishevelled 0.0009 0.0057 0.008
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Schistosoma mansoni sodium-dependent amino acid transporter 0.0047 0.087 0.122
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0504 0.0772
Onchocerca volvulus 0.0015 0.0199 0.034
Brugia malayi hypothetical protein 0.0028 0.0473 0.0473
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.1666 0.337
Brugia malayi Sugar transporter family protein 0.0015 0.0199 0.0199
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0006 0.0006
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.087 0.122
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.087 0.122
Leishmania major importin beta-1 subunit, putative 0.0025 0.0403 0.5831
Onchocerca volvulus 0.0015 0.0199 0.034
Trypanosoma brucei glucose transporter 2A 0.0034 0.0598 0.8651
Entamoeba histolytica hypothetical protein 0.0025 0.0403 0.2099
Brugia malayi Pre-SET motif family protein 0.003 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0051 0.0958 0.0958
Toxoplasma gondii histone lysine demethylase JMJD6a 0.001 0.0073 0.0112
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.087 0.122
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0034 0.0589 0.0597
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0015 0.0196 0.0275
Plasmodium falciparum protein kinase 7 0.0309 0.6521 0.6612
Toxoplasma gondii facilitative glucose transporter GT1 0.0109 0.2222 0.3408
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.087 0.087
Giardia lamblia Hexose transporter 0.0015 0.0199 0.2606
Mycobacterium ulcerans beta-lactamase 0.0037 0.0662 1
Onchocerca volvulus 0.0015 0.0199 0.034
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0473 0.6846
Plasmodium falciparum calcium-dependent protein kinase 4 0.0034 0.0589 0.0597
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.013 0.013
Onchocerca volvulus 0.003 0.0519 0.0894
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Toxoplasma gondii protein kinase, putative 0.0309 0.6521 1
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0473 0.0726
Brugia malayi glutathione reductase 0.0037 0.0656 0.0656
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0519 0.0519
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.1666 0.337
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0006 0.0002 0.0002
Schistosoma mansoni glucose transport protein 0.0109 0.2222 0.3114
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0199 0.0199
Giardia lamblia PHD finger protein 15 0.003 0.0504 0.6607
Echinococcus multilocularis snurportin 1 0.0328 0.6916 0.6916
Echinococcus multilocularis jumonji domain containing 1A 0.001 0.0073 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.013 0.013
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0574 0.0804
Schistosoma mansoni sugar transporter 0.0015 0.0199 0.0278
Brugia malayi beta-lactamase family protein 0.0037 0.0662 0.0662
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0495 0.0495
Loa Loa (eye worm) hypothetical protein 0.0037 0.0662 0.0662
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.013 0.013
Entamoeba histolytica hypothetical protein 0.0036 0.0649 0.3384
Onchocerca volvulus 0.0015 0.0199 0.034
Trichomonas vaginalis ran, putative 0.0023 0.0353 0.0702
Plasmodium vivax importin-beta 2, putative 0.0031 0.0528 0.0535
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.3714 0.6428
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0141 0.2126
Plasmodium falciparum thioredoxin reductase 0.0037 0.0656 0.0665
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0393 0.5939
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0748 0.0748
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0199 0.0199
Leishmania major glucose transporter/membrane transporter D2, putative 0.0034 0.0598 0.8651
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0353 0.0358
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0034 0.0589 0.8517
Loa Loa (eye worm) acetyltransferase 0.0154 0.3187 0.3187
Echinococcus multilocularis geminin 0.0338 0.7138 0.7138
Schistosoma mansoni sodium/chloride dependent transporter 0.0275 0.5776 0.8092
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.0598 0.8651
Echinococcus multilocularis lamin 0.0027 0.0454 0.0454
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Trypanosoma cruzi hypothetical protein 0.0006 0.0002 0.0036
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0353 0.0353
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0009 0.0057 0.0057
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0662 0.0662
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0.0141 0.1616
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0906 0.0906
Brugia malayi hypothetical protein 0.0006 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0006 0.0006
Brugia malayi DIX domain containing protein 0.0009 0.0057 0.0057
Trypanosoma brucei sugar transporter, putative 0.0015 0.0199 0.2874
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.1919 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.1666 0.8925
Loa Loa (eye worm) hypothetical protein 0.0041 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Brugia malayi hypothetical protein 0.0006 0.0006 0.0006
Schistosoma mansoni protein kinase 0.0034 0.0589 0.0825
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0033 0.0574 0.0574
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0666 0.0666
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0073 0.0102
Echinococcus granulosus expressed conserved protein 0.009 0.1795 0.1795
Schistosoma mansoni lamin 0.0027 0.0454 0.0636
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0519 0.0519
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0196 0.0196
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0473 0.6846
Loa Loa (eye worm) hypothetical protein 0.0031 0.0528 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0598 0.1187
Onchocerca volvulus 0.0275 0.5776 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.013 0.013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0275 0.5776 0.5776
Loa Loa (eye worm) hypothetical protein 0.003 0.0504 0.0504
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Plasmodium vivax SET domain protein, putative 0.003 0.0519 0.0526
Trichomonas vaginalis sugar transporter, putative 0.0034 0.0598 0.1187
Toxoplasma gondii hypothetical protein 0.0047 0.087 0.1335
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.013 0.0182
Echinococcus granulosus solute carrier family 22 0.0015 0.0199 0.0199
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0906 0.0906
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Trichomonas vaginalis sugar transporter, putative 0.0034 0.0598 0.1187
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0006
Echinococcus granulosus solute carrier family 22 0.0015 0.0199 0.0199
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0844 0.0844
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0454 0.0454
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0057 0.0057
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0662 0.1339
Echinococcus granulosus ras GTP exchange factor 0.0006 0.0002 0.0002
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0199 0.0278
Mycobacterium tuberculosis Probable reductase 0.0084 0.1666 0.337
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0057 0.0057
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.013 0.0221
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0393 0.0603
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0141 0.0143
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.087 0.087
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0033 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.0037 0.0662 0.0662
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0037 0.0662 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0393 0.0399
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0002 0.0013
Trypanosoma brucei glucose transporter 1E 0.0034 0.0598 0.8651
Loa Loa (eye worm) hypothetical protein 0.0047 0.087 0.087
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) hypothetical protein 0.0275 0.5776 0.5776
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Echinococcus multilocularis protein patched 0.0041 0.0748 0.0748
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.013 0.013
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0656 0.0656
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.013 0.013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0099 0.0139
Schistosoma mansoni survival motor neuron protein 0.0096 0.1934 0.271
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.013 0.0221
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0141 0.0141
Plasmodium falciparum calcium-dependent protein kinase 1 0.0034 0.0589 0.0597
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0033 0.0574 0.114
Mycobacterium tuberculosis Conserved protein 0.0037 0.0662 0.1339
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0275 0.5776 0.8092
Onchocerca volvulus 0.0015 0.0199 0.034
Echinococcus granulosus lamin 0.0027 0.0454 0.0454
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0662 0.0927
Schistosoma mansoni hypothetical protein 0.0328 0.6916 0.969
Trichomonas vaginalis glucose transporter, putative 0.0034 0.0598 0.1187
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0075 0.1092
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0844 0.1675
Loa Loa (eye worm) hypothetical protein 0.0471 1 1
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0199 0.2874
Brugia malayi PHD-finger family protein 0.003 0.0504 0.0504
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0006 0.0002 0.0003
Echinococcus granulosus solute carrier family 22 0.0015 0.0199 0.0199
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.1335
Schistosoma mansoni ran 0.0023 0.0353 0.0495
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0006
Plasmodium falciparum JmjC domain-containing protein, putative 0.001 0.0073 0.0074
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0057 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0578 0.0578
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0662 0.0662
Brugia malayi beta-lactamase family protein 0.0037 0.0662 0.0662
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0033 0.0574 0.0574
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0656 0.1327
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0353 0.0353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.013 0.013
Mycobacterium ulcerans lipase LipD 0.0037 0.0662 1
Plasmodium falciparum calcium-dependent protein kinase 5 0.0034 0.0589 0.0597
Leishmania major hypothetical protein, conserved 0.0028 0.0473 0.6846
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0393 0.0551
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0047 0.087 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.013 0.0221
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0006
Loa Loa (eye worm) RasGEF domain-containing protein 0.0006 0.0002 0.0002
Echinococcus multilocularis muscleblind protein 1 0.0148 0.305 0.305
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0141 0.2036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0833 0.0833
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0691 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0519 0.0796
Leishmania major hypothetical protein, conserved 0.0015 0.0199 0.2874
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0006 0.0002 0.0002
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0748 0.0748
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.087
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Brugia malayi major facilitator superfamily protein 0.0015 0.0199 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0662 0.1314
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0353 0.4637
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0833 0.0833
Brugia malayi nuclear receptor RXR 0.0006 0.0006 0.0006
Plasmodium falciparum thioredoxin reductase 0.0013 0.0141 0.0143
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.1867 1
Schistosoma mansoni sugar transporter 0.0015 0.0199 0.0278
Plasmodium vivax hypothetical protein, conserved 0.001 0.0075 0.0076
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0762 0.3971
Echinococcus multilocularis solute carrier family 22 0.0015 0.0199 0.0199
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0034 0.0589 0.0903
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0099 0.0099
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0075 0.0116
Loa Loa (eye worm) hypothetical protein 0.0037 0.0662 0.0662
Loa Loa (eye worm) hypothetical protein 0.0085 0.169 0.169
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.013 0.0182
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0141 0.7084
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.013 0.013
Entamoeba histolytica hypothetical protein 0.0024 0.0393 0.2048
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0009 0.0057 0.0057
Echinococcus multilocularis ras GTP exchange factor 0.0006 0.0002 0.0002
Onchocerca volvulus 0.0027 0.0454 0.0781
Echinococcus granulosus intermediate filament protein 0.0027 0.0454 0.0454
Brugia malayi hypothetical protein 0.0036 0.0649 0.0649
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0141 0.0143
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0199 0.0199
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0833 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0748 0.1485
Brugia malayi Importin beta-1 subunit 0.0031 0.0528 0.0528
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0662 0.0662
Brugia malayi nuclear receptor NHR-88 0.0012 0.013 0.013
Treponema pallidum NADH oxidase 0.0013 0.0141 0.0244
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0139 0.0139
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0328 0.0652
Schistosoma mansoni phosphatidylserine receptor 0.001 0.0073 0.0102
Echinococcus granulosus General substrate transporter 0.0094 0.1891 0.1891
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0589 0.0589
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.013 0.013
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0574 0.0804
Echinococcus multilocularis solute carrier family 22 0.0015 0.0199 0.0199
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0199 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0199 0.0394
Onchocerca volvulus 0.0047 0.087 0.1503
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0393 0.5939
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.015 0.015
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0096 0.1934 0.271
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0353 0.0353
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0009 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0589 0.0589
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0057 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0196 0.0196
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0504 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.013 0.013
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.013 0.0182
Brugia malayi major facilitator superfamily protein 0.0015 0.0199 0.0199
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0199 0.0199
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0473 0.048
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0589 0.1169
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0199 0.2874
Onchocerca volvulus Putative transporter 0.0015 0.0199 0.034
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0528 0.7638
Onchocerca volvulus 0.0037 0.0662 0.1142
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0544 0.0544
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0528 0.7638
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0662 0.1339
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0519 0.0727
Trypanosoma brucei glucose transporter, putative 0.0034 0.0598 0.8651
Trypanosoma cruzi hypothetical protein 0.0006 0.0002 0.0036
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.087 0.087
Trichomonas vaginalis ras GTP exchange factor, putative 0.0006 0.0002 0.0005
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0328 0.6916 0.6916
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0199 0.3001
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0748 0.0748
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.1666 0.337
Entamoeba histolytica protein kinase, putative 0.0034 0.0589 0.3067
Plasmodium falciparum protein kinase 6 0.0464 0.9862 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0015 0.0196 0.0275
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0177 0.3673 0.3724
Loa Loa (eye worm) hypothetical protein 0.0012 0.013 0.013
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.2222 0.2222
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Echinococcus multilocularis Protein son of sevenless 0.0006 0.0002 0.0002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.087 0.1335
Schistosoma mansoni lamin 0.0027 0.0454 0.0636
Brugia malayi Pre-SET motif family protein 0.0211 0.4409 0.4409
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0637 0.0893
Onchocerca volvulus 0.0015 0.0199 0.034
Giardia lamblia Prolyl-tRNA synthetase 0.0033 0.0574 0.753
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0141 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0833 0.1167
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0057 0.0057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.013 0.0182
Loa Loa (eye worm) hypothetical protein 0.003 0.0519 0.0519
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0833 0.0833
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0403 0.08
Loa Loa (eye worm) hypothetical protein 0.0148 0.305 0.305
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0006 0.0002 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0662 0.0671
Brugia malayi hypothetical protein 0.0015 0.0199 0.0199
Brugia malayi N-terminal motif family protein 0.0006 0.0002 0.0002
Plasmodium vivax CDK-related protein kinase 6, putative 0.0464 0.9862 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0844 0.1294
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0199 0.0394
Schistosoma mansoni jumonji domain containing protein 0.001 0.0073 0.0102
Plasmodium vivax hypothetical protein, conserved 0.003 0.0504 0.0511
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.1951 0.1951
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0006 0.0002 0.0036
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0182 0.0182
Mycobacterium tuberculosis Conserved protein 0.0037 0.0662 0.1339
Echinococcus granulosus solute carrier family 22 0.0015 0.0199 0.0199
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.087 0.122
Leishmania major hypothetical protein, conserved 0.001 0.0073 0.1054
Onchocerca volvulus 0.0096 0.1934 0.3346
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0199 0.0199
Plasmodium falciparum calcium-dependent protein kinase 3 0.0034 0.0589 0.0597
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0637 0.0637
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0393 0.2106
Brugia malayi Bromodomain containing protein 0.0033 0.0585 0.0585
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0158 0.0158
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0199 0.0394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0141 0.2036
Loa Loa (eye worm) hypothetical protein 0.0033 0.0574 0.0574
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0199 0.0402
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.013 0.013

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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