Detailed information for compound 786793

Basic information

Technical information
  • TDR Targets ID: 786793
  • Name: 3-(5-bromothiophen-2-yl)sulfonyl-N-[4-chloro- 3-(trifluoromethyl)phenyl]propanamide
  • MW: 476.716 | Formula: C14H10BrClF3NO3S2
  • H donors: 1 H acceptors: 3 LogP: 4.52 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(c(c1)C(F)(F)F)Cl)CCS(=O)(=O)c1ccc(s1)Br
  • InChi: 1S/C14H10BrClF3NO3S2/c15-11-3-4-13(24-11)25(22,23)6-5-12(21)20-8-1-2-10(16)9(7-8)14(17,18)19/h1-4,7H,5-6H2,(H,20,21)
  • InChiKey: LFUBBOYGXSBEIR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[(5-bromo-2-thienyl)sulfonyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]propanamide
  • 3-[(5-bromo-2-thienyl)sulfonyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0037 0.033
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0024 0.0006 0.0055
Schistosoma mansoni smad1 5 8 and 0.0053 0.0049 0.0367
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0021 0.0104
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0028 0.0027
Loa Loa (eye worm) dehydrogenase 0.002 0.0001 0.0008
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0028 0.2024
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0067 0.0068 0.0068
Echinococcus multilocularis glycoprotein Antigen 5 0.0037 0.0025 0.0037
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Onchocerca volvulus Matrilysin homolog 0.0021 0.0003 0.0028
Schistosoma mansoni mannose-1-phosphate guanyltransferase 0.0034 0.0022 0.0161
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0033 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Schistosoma mansoni hypothetical protein 0.0102 0.0119 0.0909
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0014 0.0347
Leishmania major hypothetical protein, conserved 0.0062 0.0061 0.1539
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Toxoplasma gondii eukaryotic initiation factor-2B, epsilon subunit, putative 0.0033 0.002 0.0099
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0102 0.0119 0.0176
Echinococcus multilocularis somatostatin receptor 0.0102 0.0119 0.0176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0212
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.005 0.1354
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0077 0.0588
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0004 0.0024
Echinococcus multilocularis sex peptide receptor 0.0102 0.0119 0.0176
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0003 0.001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0028 0.1997
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0109 0.0129 0.3296
Brugia malayi AMP-binding enzyme family protein 0.0026 0.001 0.0083
Schistosoma mansoni steroid hormone receptor ad4bp 0.0045 0.0037 0.0277
Echinococcus granulosus lysosomal alpha glucosidase 0.0147 0.0183 0.0618
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0083 0.0092 0.6805
Loa Loa (eye worm) hypothetical protein 0.0571 0.0791 0.6683
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0103 0.012 0.0405
Schistosoma mansoni hypothetical protein 0.013 0.0159 0.1221
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0102 0.0119 0.1004
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0223 0.0292 0.0987
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.001 0.001
Echinococcus granulosus ecdysone induced protein 78C 0.0045 0.0037 0.0125
Schistosoma mansoni amine GPCR 0.0102 0.0119 0.0909
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0045 0.0037 0.033
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0006 0.0051
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0045 0.0037 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0003 0.0015
Brugia malayi G protein-coupled receptor 0.0102 0.0119 0.1082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Echinococcus multilocularis Protein lozenge 0.0043 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0024 0.0175
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0003 0.0004
Echinococcus granulosus serotonin receptor 0.0102 0.0119 0.0402
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0031 0.0777
Loa Loa (eye worm) nucleotidyl transferase 0.0034 0.0022 0.0185
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Giardia lamblia Kinase, PLK 0.0109 0.0129 0.1086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0113 0.0135 0.1138
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0103 0.012 0.3049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0021 0.0522
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0119 0.0402
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0102 0.0119 0.0909
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0045 0.0037 0.0312
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0004 0.0006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0024 0.0006 0.0043
Schistosoma mansoni Smad4 0.0053 0.0049 0.0367
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0003 0.0024
Echinococcus granulosus GPCR family 2 0.013 0.0159 0.0539
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis maltase-glucoamylase, putative 0.0033 0.0019 0.0495
Toxoplasma gondii PHD-finger domain-containing protein 0.0052 0.0046 0.0233
Schistosoma mansoni alpha-glucosidase 0.0126 0.0153 0.1175
Echinococcus granulosus hypothetical protein 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0038 0.1023
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0038 0.1023
Leishmania major hypothetical protein, conserved 0.0103 0.012 0.3049
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0102 0.0119 0.0176
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) hypothetical protein 0.0492 0.0678 0.5733
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0223 0.0292 0.0433
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0067 0.0226
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.017 0.4347
Trypanosoma brucei polo-like protein kinase 0.0109 0.0129 0.3296
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0001 0.0033
Echinococcus multilocularis fmrfamide receptor 0.0102 0.0119 0.0176
Plasmodium falciparum ataxin-2 like protein, putative 0.0062 0.0061 0.4505
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Trichomonas vaginalis glucose-1-phosphate thymidylyltransferase, putative 0.0034 0.0022 0.0573
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0077 0.0083 0.0123
Echinococcus granulosus TGF beta signal transducer SmadC 0.0053 0.0049 0.0164
Echinococcus multilocularis L aminoadipate semialdehyde 0.0075 0.008 0.0118
Loa Loa (eye worm) CBP-B 0.0063 0.0063 0.0534
Loa Loa (eye worm) hypothetical protein 0.007 0.0073 0.0614
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trypanosoma cruzi hypothetical protein 0.0033 0.002 0.0497
Brugia malayi Trypsin family protein 0.0037 0.0025 0.0222
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0037 0.0277
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0103 0.012 0.3049
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0033 0.002 0.1449
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0113 0.0135 1
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0033 0.002 0.053
Echinococcus granulosus jumonji domain containing protein 0.0072 0.0075 0.0255
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.8892
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0045 0.0037 0.0277
Giardia lamblia Kinase, CMGC MAPK 0.0046 0.0038 0.0316
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.0119 0.0402
Echinococcus multilocularis Smad4 0.0053 0.0049 0.0072
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.6992 1 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0045 0.0037 0.0277
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0019 0.0464
Schistosoma mansoni opsin-like receptor 0.0102 0.0119 0.0909
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0154 0.0193 0.0654
Loa Loa (eye worm) PDE1B protein 0.0103 0.012 0.1012
Schistosoma mansoni lamin 0.0025 0.0009 0.0061
Echinococcus multilocularis musashi 0.0025 0.0009 0.0013
Brugia malayi zgc:92842 0.0033 0.002 0.0178
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0006 0.0055
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0001 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0844 0.1183 0.6054
Onchocerca volvulus 0.0102 0.0119 0.174
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0084 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.012 0.3049
Brugia malayi Inositol-1 0.0069 0.0071 0.0645
Plasmodium falciparum liver specific protein 2, putative 0.0033 0.002 0.1478
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0074 0.0079 0.0078
Onchocerca volvulus 0.0102 0.0119 0.174
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus multilocularis orexin receptor type 2 0.0102 0.0119 0.0176
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0025 0.0037
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0001 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0038 0.0288
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Schistosoma mansoni cpg binding protein 0.0061 0.0061 0.0459
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0028 0.0226
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0045 0.0037 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0107 0.0125 0.1058
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Toxoplasma gondii exonuclease III APE 0.0039 0.0028 0.0137
Brugia malayi Protein kinase domain containing protein 0.006 0.0058 0.0524
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0102 0.0119 0.1004
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Brugia malayi G-protein coupled receptor 0.0102 0.0119 0.1082
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0083 0.0092 0.0777
Brugia malayi Tachykinin-like peptides receptor 99D 0.0102 0.0119 0.1082
Entamoeba histolytica hypothetical protein 0.0078 0.0084 0.6219
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.0119 0.0909
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0169 0.0215 0.0726
Echinococcus granulosus CREB binding protein 0.0091 0.0103 0.0349
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0009 0.0078
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0046 0.0038 0.0959
Brugia malayi Serotonin receptor 0.0102 0.0119 0.1082
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus granulosus mitogen activated protein kinase 0.0046 0.0038 0.013
Echinococcus granulosus neuropeptide FF receptor 2 0.0102 0.0119 0.0402
Schistosoma mansoni ap endonuclease 0.0039 0.0028 0.0206
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Onchocerca volvulus 0.0344 0.0465 0.6851
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.001 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0102 0.0119 0.0176
Brugia malayi MH2 domain containing protein 0.0053 0.0049 0.0437
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0033 0.002 0.003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0028 0.0012 0.0018
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0091 0.0103 0.0788
Echinococcus granulosus G protein coupled receptor 139 0.0102 0.0119 0.0402
Echinococcus multilocularis jumonji domain containing protein 0.0072 0.0075 0.0112
Echinococcus granulosus tachykinin peptides receptor 99D 0.0102 0.0119 0.0402
Onchocerca volvulus 0.0102 0.0119 0.174
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0071 0.1803
Echinococcus multilocularis geminin 0.0835 0.117 0.1735
Schistosoma mansoni hypothetical protein 0.0282 0.0376 0.2892
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Schistosoma mansoni amine GPCR 0.0102 0.0119 0.0909
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0077 0.0588
Brugia malayi jmjC domain containing protein 0.0066 0.0067 0.0603
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0045 0.0037 0.0125
Schistosoma mansoni nuclear receptor 0.0021 0.0003 0.0015
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0028 0.0041
Brugia malayi Nucleotidyl transferase family protein 0.0034 0.0022 0.0192
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0077 0.0588
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0129 0.099
Mycobacterium tuberculosis Conserved hypothetical protein 0.1214 0.1714 0.1713
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.0119 0.0402
Loa Loa (eye worm) inositol-1 0.0069 0.0071 0.0602
Onchocerca volvulus 0.0026 0.001 0.0134
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0003 0.0151
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0029 0.0014 0.0021
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus multilocularis lysosomal alpha glucosidase 0.0147 0.0183 0.0271
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Onchocerca volvulus 0.0036 0.0024 0.0335
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0001 0.0033
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0018
Onchocerca volvulus 0.0102 0.0119 0.174
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0006 0.0051
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0113 0.0135 0.02
Onchocerca volvulus 0.0021 0.0003 0.0028
Echinococcus multilocularis neuropeptide s receptor 0.0102 0.0119 0.0176
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0052 0.0046 0.035
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0742 0.1036 0.9494
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Brugia malayi Trypsin family protein 0.0037 0.0025 0.0222
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0003 0.0041
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0045 0.0037 0.0125
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Onchocerca volvulus 0.0102 0.0119 0.174
Mycobacterium ulcerans hypothetical protein 0.0037 0.0025 0.0025
Echinococcus multilocularis neutral alpha glucosidase AB 0.0033 0.0019 0.0028
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0212
Plasmodium falciparum phosphodiesterase gamma, putative 0.0103 0.012 0.8892
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.0119 0.0909
Onchocerca volvulus Protein ultraspiracle homolog 0.0045 0.0037 0.0531
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.002 0.0497
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0119 0.0176
Schistosoma mansoni nuclear receptor 0.0021 0.0003 0.0015
Echinococcus granulosus dynactin 5 p25 0.0033 0.002 0.0069
Schistosoma mansoni neuropeptide receptor 0.0102 0.0119 0.0909
Brugia malayi Trypsin-like protease protein 5 0.0037 0.0025 0.0222
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.0119 0.0176
Plasmodium falciparum cysteine repeat modular protein 1 0.006 0.0058 0.4291
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0074 0.0079 0.0079
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0069 0.0071 0.0071
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.001 0.001
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0001 0.0003
Loa Loa (eye worm) nuclear factor I 0.0029 0.0015 0.0123
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0113 0.0135 0.103
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Onchocerca volvulus 0.0037 0.0025 0.0357
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0045 0.0037 0.0277
Brugia malayi Pre-SET motif family protein 0.0036 0.0024 0.0208
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0029 0.0014 0.0347
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus granulosus geminin 0.0835 0.117 0.3958
Plasmodium vivax cysteine repeat modular protein 1, putative 0.006 0.0058 0.4291
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0028 0.0245
Brugia malayi hypothetical protein 0.0037 0.0025 0.0222
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0071 0.1923
Brugia malayi GnHR receptor homolog 0.0102 0.0119 0.1082
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0075 0.008 0.0721
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.6992 1 1
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0037 0.0025 0.0037
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.001 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.012 0.3251
Loa Loa (eye worm) MH1 domain-containing protein 0.0053 0.0049 0.0411
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0151 0.1157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0103 0.012 0.0405
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0003 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.0119 0.0402
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Brugia malayi isocitrate dehydrogenase 0.0034 0.0021 0.0187
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.0129 0.9608
Brugia malayi Pax transcription factor protein 2 0.0184 0.0236 0.2158
Mycobacterium ulcerans d-alpha-D-mannose-1-phosphate guanylyltransferase ManB 0.0034 0.0022 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0045 0.0037 0.0312
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0154 0.0193 0.0654
Mycobacterium tuberculosis Conserved hypothetical protein 0.1214 0.1714 0.1713
Brugia malayi MH2 domain containing protein 0.078 0.1091 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Schistosoma mansoni hypothetical protein 0.013 0.0159 0.1221
Onchocerca volvulus 0.006 0.0058 0.0843
Loa Loa (eye worm) latrophilin receptor protein 2 0.013 0.0159 0.1346
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Echinococcus granulosus peptide allatostatin:somatostatin 0.0102 0.0119 0.0402
Brugia malayi CXXC zinc finger family protein 0.0058 0.0056 0.0503
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0034 0.0022 0.0074
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.0103 0.012 0.1012
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.0391 1
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.0119 0.0909
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Brugia malayi GDP-mannose pyrophosphorylase B 0.0034 0.0022 0.0192
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0046 0.0038 0.0959
Onchocerca volvulus 0.0102 0.0119 0.174
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Onchocerca volvulus 0.0085 0.0094 0.1373
Echinococcus granulosus mothers against decapentaplegic 6 0.0024 0.0006 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0037 0.033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0119 0.0909
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Brugia malayi hypothetical protein 0.0283 0.0379 0.3467
Loa Loa (eye worm) hypothetical protein 0.0512 0.0707 0.5973
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0169 0.0215 0.0318
Schistosoma mansoni cpg binding protein 0.0061 0.0061 0.0459
Loa Loa (eye worm) hypothetical protein 0.0344 0.0465 0.393
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0033 0.0019 0.0161
Echinococcus granulosus CREB binding protein 0.0056 0.0053 0.0179
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0018
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0033 0.0019 0.0093
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Schistosoma mansoni lozenge 0.0043 0.0034 0.0256
Schistosoma mansoni alpha-glucosidase 0.0126 0.0153 0.1175
Loa Loa (eye worm) hypothetical protein 0.0571 0.0791 0.6683
Brugia malayi G protein-coupled receptor F59B2.13 0.0102 0.0119 0.1082
Schistosoma mansoni hypothetical protein 0.0102 0.0119 0.0909
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0154 0.0193 0.1634
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Echinococcus granulosus orexin receptor type 2 0.0102 0.0119 0.0402
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0391 1
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0103 0.012 0.3049
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.012 0.3049
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0003 0.0017
Onchocerca volvulus 0.0037 0.0025 0.0357
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0103 0.012 0.3049
Loa Loa (eye worm) hypothetical protein 0.002 0 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0033 0.002 0.0149
Trypanosoma cruzi serine acetyltransferase, putative 0.0033 0.002 0.0497
Echinococcus multilocularis serotonin receptor 0.0102 0.0119 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0045 0.0037 0.0312
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0102 0.0119 0.0176
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Toxoplasma gondii GDP-D-mannose pyrophosphorylase 0.0034 0.0022 0.0107
Brugia malayi Dopamine receptor 0.0102 0.0119 0.1082
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0021 0.0522
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0102 0.0119 0.0176
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0154 0.0193 0.1765
Echinococcus granulosus g protein coupled receptor 0.0102 0.0119 0.0402
Brugia malayi MH1 domain containing protein 0.0053 0.0049 0.0437
Echinococcus granulosus 7TM GPCR rhodopsin 0.0102 0.0119 0.0402
Schistosoma mansoni neuropeptide receptor 0.0102 0.0119 0.0909
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0045 0.0037 0.0531
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0062 0.0092
Mycobacterium ulcerans transferase 0.0033 0.002 0.002
Echinococcus granulosus 7tm_1 domain containing protein 0.0102 0.0119 0.0402
Loa Loa (eye worm) hypothetical protein 0.0103 0.012 0.1012
Schistosoma mansoni histamine h1 receptor 0.0102 0.0119 0.0909
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.001 0.001
Plasmodium falciparum glutathione reductase 0.0029 0.0014 0.1041
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0003 0.0017
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0075 0.008 0.0606
Schistosoma mansoni neuropeptide receptor 0.0102 0.0119 0.0909
Plasmodium falciparum ataxin-2 like protein, putative 0.0062 0.0061 0.4505
Schistosoma mansoni smad 0.0053 0.0049 0.0367
Loa Loa (eye worm) dehydrogenase 0.002 0.0001 0.0008
Echinococcus multilocularis transmembrane protease serine 3 0.0037 0.0025 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0045 0.0037 0.033
Echinococcus granulosus fmrfamide receptor 0.0102 0.0119 0.0402
Echinococcus granulosus glycoprotein Antigen 5 0.0037 0.0025 0.0085
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0103 0.012 0.109
Echinococcus multilocularis smad 0.0053 0.0049 0.0072
Onchocerca volvulus 0.0102 0.0119 0.174
Echinococcus granulosus hypothetical protein 0.002 0.0001 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.0045 0.0037 0.0531
Toxoplasma gondii aldehyde dehydrogenase 0.0223 0.0292 0.1489
Mycobacterium leprae POSSIBLE TRANSFERASE 0.0033 0.002 0.0019
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.0003 0.0015
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0142 0.0176 0.2581
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0037 0.033
Brugia malayi Matrixin family protein 0.0051 0.0046 0.0414
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0055
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0029 0.0014 0.1041
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0021 0.0187
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0034 0.0022 0.0537
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0001 0.0003
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0103 0.012 0.8892
Entamoeba histolytica acetyltransferase, putative 0.0033 0.002 0.1449
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0019 0.0495
Schistosoma mansoni amine GPCR 0.0102 0.0119 0.0909
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0021 0.0072
Toxoplasma gondii hypothetical protein 0.0047 0.004 0.0199
Trichomonas vaginalis set domain proteins, putative 0.0275 0.0366 1
Mycobacterium ulcerans hypothetical protein 0.1214 0.1714 0.1713
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0003 0.001
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0001 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0045 0.0037 0.033
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.0119 0.0402
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0001 0.0001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0102 0.0119 0.174
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0742 0.1036 0.3503
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Brugia malayi photoreceptor-specific nuclear receptor 0.0045 0.0037 0.033
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.0129 0.3296
Schistosoma mansoni jumonji domain containing protein 0.0134 0.0165 0.1264
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Mycobacterium tuberculosis Probable oxidoreductase 0.1176 0.1659 0.1659
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0046 0.0038 0.0324
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0844 0.1183 0.1754
Trypanosoma brucei GDP-mannose pyrophosphorylase 0.0034 0.0022 0.0537
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0003 0.0024
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0102 0.0119 0.1082
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0045 0.0037 0.0055
Echinococcus multilocularis GPCR, family 2 0.013 0.0159 0.0236
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.002 0.0497
Brugia malayi nuclear hormone receptor 0.0021 0.0003 0.0017
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Toxoplasma gondii hypothetical protein 0.0029 0.0014 0.0069
Giardia lamblia Rab geranylgeranyltransferase 0.0029 0.0014 0.0114
Brugia malayi Trypsin family protein 0.0396 0.0541 0.4954
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0045 0.0037 0.0312
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0071 0.1803
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0077 0.0653
Toxoplasma gondii PHD-finger domain-containing protein 0.0052 0.0046 0.0233
Loa Loa (eye worm) TYRA-2 protein 0.0102 0.0119 0.1004
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0072 0.0075 0.0254
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0024 0.0175
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0103 0.012 0.8892
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0028 0.0685
Loa Loa (eye worm) MH2 domain-containing protein 0.0053 0.0049 0.0411
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0391 1
Echinococcus granulosus microtubule associated protein 2 0.0827 0.1159 0.3919
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0037 0.033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0223 0.0292 0.0291
Trichomonas vaginalis sucrase-isomaltase, putative 0.0033 0.0019 0.0495
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) hypothetical protein 0.007 0.0073 0.0614
Echinococcus granulosus neuropeptide receptor 0.0102 0.0119 0.0402
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0045 0.0037 0.0312
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0003 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0045 0.0037 0.033
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Schistosoma mansoni hypothetical protein 0.0835 0.117 0.9013
Brugia malayi Bromodomain containing protein 0.0053 0.0049 0.0438
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.0119 0.1004
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0019 0.0464
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.002 0.0497
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0021 0.0003 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0025 0.0186
Entamoeba histolytica translation initiation factor eIF-2B epsilon subunit, putative 0.0034 0.0022 0.1565
Brugia malayi serine/threonine-protein kinase plk-2 0.0109 0.0129 0.1178
Brugia malayi nuclear receptor NHR-88 0.0021 0.0003 0.0017
Loa Loa (eye worm) steroid hormone receptor 0.0045 0.0037 0.0312
Onchocerca volvulus 0.0037 0.0025 0.0357
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0037 0.0055
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0037 0.033
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.001 0.0678
Leishmania major hypothetical protein, conserved 0.0103 0.012 0.3049
Echinococcus granulosus allatostatin A receptor 0.0102 0.0119 0.0402
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0024 0.0175
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0103 0.012 0.109
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0103 0.012 0.0178
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0006 0.0043
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0067 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Mycobacterium tuberculosis Possible siderophore-binding protein 0.0033 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus granulosus inositol monophosphatase 1 0.0069 0.0071 0.0241
Onchocerca volvulus 0.0102 0.0119 0.174
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0024 0.0006 0.001
Brugia malayi ecdysteroid receptor 0.0045 0.0037 0.033
Onchocerca volvulus 0.0275 0.0366 0.5395
Brugia malayi putative neuropeptide receptor NPR1 0.0102 0.0119 0.1082
Schistosoma mansoni CREB-binding protein 2 0.0091 0.0103 0.0788
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0083 0.0092 0.2334
Leishmania major serine acetyltransferase 0.0033 0.002 0.0497
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0154 0.0193 0.1483
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0102 0.0119 0.1004
Brugia malayi hypothetical protein 0.0033 0.002 0.0178
Echinococcus multilocularis enteropeptidase 0.0037 0.0025 0.0037
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0021 0.0032
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0844 0.1183 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Giardia lamblia hypothetical protein 0.0103 0.012 0.1005
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0001 0.0033
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0103 0.012 0.0916
Brugia malayi TAR-binding protein 0.0073 0.0077 0.07
Schistosoma mansoni glucosamine-1-phosphate N-acetyltransferase 0.0034 0.0022 0.0161
Echinococcus multilocularis dynactin 5 p25 0.0033 0.002 0.003
Loa Loa (eye worm) hypothetical protein 0.007 0.0073 0.0614
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.8892
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0021 0.1551
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0046 0.0038 0.0191
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0019 0.0495
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Wolbachia endosymbiont of Brugia malayi carbonic anhydrase 0.0033 0.002 0.0019
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0004 0.0024
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.013 0.0159 0.0236
Echinococcus multilocularis neuropeptide FF receptor 2 0.0102 0.0119 0.0176
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Schistosoma mansoni hypothetical protein 0.0395 0.0539 0.4146
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Onchocerca volvulus 0.0102 0.0119 0.174
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0018
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.0129 0.3296
Brugia malayi hypothetical protein 0.0024 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0212
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0028 0.0027
Echinococcus granulosus oxidoreductase 0.002 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0037 0.0025 0.0186
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0001 0.0003
Brugia malayi hypothetical protein 0.0344 0.0465 0.4257
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0119 0.0176
Echinococcus granulosus g protein coupled receptor 0.0102 0.0119 0.0402
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0055
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0102 0.0119 0.0402
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.1214 0.1714 0.8769
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Trichomonas vaginalis sugar-1-phosphate guanyl transferase, putative 0.0034 0.0022 0.0573
Loa Loa (eye worm) transcription factor SMAD2 0.078 0.1091 0.9221
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0001 0.0003
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0103 0.012 0.109
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.0539 0.0799
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0109 0.0129 0.1094
Loa Loa (eye worm) pax transcription factor protein 2 0.0184 0.0236 0.1996
Brugia malayi mothers against decapentaplegic homolog 3 0.0024 0.0006 0.0051
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0412 0.0563 0.5157
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0033 0.002 0.053
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0223 0.0292 0.0291
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0003 0.0004
Brugia malayi hypothetical protein 0.0021 0.0003 0.0017
Echinococcus multilocularis transcription factor Dp 1 0.0048 0.0042 0.0062
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0014 0.0347
Echinococcus multilocularis G-protein coupled receptor, putative 0.0102 0.0119 0.0176
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0242 0.0319 0.2695
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0069 0.0071 0.5256
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.002 0.1478
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0103 0.012 0.0916
Brugia malayi nuclear receptor RXR 0.0021 0.0003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0103 0.012 0.1012
Brugia malayi follicle stimulating hormone receptor 0.0102 0.0119 0.1082
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0071 0.1803
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.0391 1
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0014 0.0347
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0009 0.0072
Onchocerca volvulus 0.0025 0.0009 0.0116
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0077 0.0653
Loa Loa (eye worm) matrixin family protein 0.0047 0.004 0.0338
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.013 0.0159 0.0236
Echinococcus multilocularis dro:myosuppressin receptor 0.0102 0.0119 0.0176
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0058 0.1465
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0119 0.0402
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0077 0.0588
Brugia malayi hypothetical protein 0.0033 0.002 0.0178
Echinococcus multilocularis Mastin 0.0037 0.0025 0.0037
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0003 0.0017
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0396 0.0541 0.4572
Brugia malayi Pre-SET motif family protein 0.0242 0.0319 0.2916
Mycobacterium leprae PROBABLE HYDROLASE 0.0026 0.0009 0.0009
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0103 0.012 0.109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0003 0.0004
Brugia malayi ORL1-like opioid receptor 0.0102 0.0119 0.1082
Trypanosoma cruzi PAB1-binding protein , putative 0.0062 0.0061 0.1539
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3049
Entamoeba histolytica acetyltransferase, putative 0.0033 0.002 0.1449
Echinococcus multilocularis oxidoreductase 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Schistosoma mansoni retinoic acid receptor RXR 0.0045 0.0037 0.0277
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0028 0.0093
Onchocerca volvulus 0.0045 0.0037 0.0531
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0031 0.0777
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0223 0.0292 0.7462
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0003 0.0004
Brugia malayi latrophilin 2 splice variant baaae 0.0282 0.0376 0.3443
Entamoeba histolytica hypothetical protein 0.0078 0.0084 0.6219
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0037 0.0277
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0028 0.0147
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.001 0.0678
Echinococcus multilocularis fmrfamide receptor 0.0102 0.0119 0.0176
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0003 0.001
Entamoeba histolytica acetyltransferase, putative 0.0033 0.002 0.1449
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.0119 0.0909
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) hypothetical protein 0.002 0 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0033 0.002 0.0172
Loa Loa (eye worm) hypothetical protein 0.002 0 0.0004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0102 0.0119 0.0402
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0113 0.0135 0.0455
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0084
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0029 0.0014 0.1041
Leishmania major GDP-mannose pyrophosphorylase 0.0034 0.0022 0.0537
Plasmodium falciparum dynactin subunit 5, putative 0.0033 0.002 0.1478
Brugia malayi Dopamine receptor protein 1 0.0102 0.0119 0.1082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0102 0.0119 0.1004
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0003 0.0024
Mycobacterium ulcerans hypothetical protein 0.0026 0.001 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Brugia malayi eIF4-gamma/eIF5/eIF2-epsilon family protein 0.0033 0.002 0.0178
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0021 0.0522
Plasmodium vivax hypothetical protein, conserved 0.0033 0.002 0.1478
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0103 0.012 0.3049
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.001 0.001
Echinococcus granulosus peregrin 0.0053 0.0049 0.0165
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0029 0.0014 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.012 0.3049
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.0119 0.0402
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0004 0.0014
Giardia lamblia Hypothetical protein 0.0103 0.012 0.1005
Entamoeba histolytica acetyltransferase, putative 0.0033 0.002 0.1449
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.002 0.0497
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.02
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.0119 0.0176
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0067 0.0564
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0034 0.0022 0.0537
Brugia malayi hypothetical protein 0.004 0.003 0.0262
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0103 0.012 0.3049
Schistosoma mansoni microtubule-associated protein tau 0.0827 0.1159 0.8924
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0103 0.012 0.0178
Leishmania major hypothetical protein, conserved 0.0033 0.002 0.0497
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Giardia lamblia Translation initiation factor 0.0033 0.002 0.0164
Plasmodium vivax mannose-1-phosphate guanyltransferase, putative 0.0034 0.0022 0.1593
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Schistosoma mansoni myosin xvIII 0.0102 0.0119 0.0909
Toxoplasma gondii thioredoxin reductase 0.0029 0.0014 0.0069
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0046 0.0038 0.0959
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0021 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0193 0.0192
Echinococcus granulosus mothers against decapentaplegic 5 0.0053 0.0049 0.0164
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0021 0.0522
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0033 0.002 0.002
Plasmodium vivax dynactin subunit 5, putative 0.0033 0.002 0.1478
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0033 0.002 0.1449
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0029 0.0014 0.0347
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Entamoeba histolytica serine acetyltransferase 1 0.0033 0.002 0.1449
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0103 0.012 0.3049
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0021 0.0157
Mycobacterium ulcerans aldehyde dehydrogenase 0.0223 0.0292 0.0291
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0074 0.0079 0.0079
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0396 0.0541 0.4162
Brugia malayi steroid hormone receptor 0.0045 0.0037 0.033
Brugia malayi TAZ zinc finger family protein 0.0091 0.0103 0.0938
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0019 0.0495
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0028 0.0685
Schistosoma mansoni inositol monophosphatase 0.0069 0.0071 0.0542
Schistosoma mansoni survival motor neuron protein 0.0058 0.0055 0.0419
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.001 0.001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0147 0.0183 0.1667
Trypanosoma cruzi Translation initiation factor eIF-2B subunit epsilon, putative 0.0034 0.0022 0.0537
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma cruzi serine acetyltransferase, putative 0.0033 0.002 0.0497
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0038 0.1023
Onchocerca volvulus 0.0492 0.0678 1
Echinococcus granulosus neuropeptide s receptor 0.0102 0.0119 0.0402
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus multilocularis mannose 1 phosphate guanyltransferase 0.0034 0.0022 0.0032
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Onchocerca volvulus Alhambra homolog 0.0052 0.0046 0.0671
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0003 0.0024
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0062 0.0061 0.006
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0029 0.0014 0.1011
Mycobacterium ulcerans serine acetyltransferase CysE 0.0033 0.002 0.002
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.8892
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0045 0.0037 0.033
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0103 0.012 0.3049
Echinococcus granulosus Smad4 0.0053 0.0049 0.0164
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0102 0.0119 0.0402
Echinococcus granulosus lamin 0.0025 0.0009 0.003
Loa Loa (eye worm) MH2 domain-containing protein 0.078 0.1091 0.9221
Brugia malayi nuclear receptor NHR-88 0.0045 0.0037 0.033
Entamoeba histolytica hypothetical protein 0.0021 0.0003 0.0118
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0072 0.0075 0.0571
Onchocerca volvulus 0.0075 0.008 0.116
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus multilocularis peregrin 0.0053 0.0049 0.0072
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0033 0.002 0.1449
Echinococcus granulosus dro:myosuppressin receptor 0.0102 0.0119 0.0402
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Loa Loa (eye worm) hypothetical protein 0.0088 0.0099 0.0839
Brugia malayi Melatonin receptor type 1A 0.0102 0.0119 0.1082
Brugia malayi Dopamine receptor protein 2 0.0102 0.0119 0.1082
Onchocerca volvulus 0.003 0.0016 0.0216
Echinococcus granulosus neuropeptide receptor 0.0102 0.0119 0.0402
Plasmodium falciparum thioredoxin reductase 0.0029 0.0014 0.1041
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0071 0.1803
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0075 0.0075
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0045 0.0037 0.0055
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0053 0.0049 0.0072
Trypanosoma brucei trypanothione reductase 0.0029 0.0014 0.0347
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus granulosus Mastin 0.0037 0.0025 0.0085
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.1214 0.1714 0.1713
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0024 0.0035
Loa Loa (eye worm) hypothetical protein 0.0844 0.1183 1
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0102 0.0119 0.0176
Schistosoma mansoni amine GPCR 0.0102 0.0119 0.0909
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0113 0.0135 1
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0119 0.0909
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0053 0.0049 0.0367
Echinococcus granulosus expressed protein 0.0293 0.0393 0.1329
Leishmania major hypothetical protein, conserved 0.006 0.0058 0.1465
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0083 0.0092 0.2334
Loa Loa (eye worm) DR-78 0.0021 0.0003 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0019 0.014
Schistosoma mansoni alpha-1 adrenergic receptor 0.0102 0.0119 0.0909
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0102 0.0119 0.174
Entamoeba histolytica hypothetical protein 0.0078 0.0084 0.6219
Brugia malayi putative neuropeptide receptor 0.0102 0.0119 0.1082
Leishmania major trypanothione reductase 0.0029 0.0014 0.0347
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0029 0.0014 0.0049
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0109 0.0129 0.0192
Brugia malayi nuclear receptor RXR 0.0024 0.0006 0.0051
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0028 0.0234
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0102 0.0119 0.0176
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3049
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0046 0.0393
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Plasmodium vivax phosphodiesterase gamma, putative 0.0103 0.012 0.8892
Brugia malayi MH1 domain containing protein 0.0053 0.0049 0.0437
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.0119 0.0176
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0021 0.0003 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0025 0.0186
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0154 0.0193 0.0287
Schistosoma mansoni hypothetical protein 0.0058 0.0055 0.0419
Schistosoma mansoni neuropeptide receptor 0.0102 0.0119 0.0909
Onchocerca volvulus Matrilysin homolog 0.0047 0.004 0.0576
Onchocerca volvulus 0.0029 0.0014 0.0199
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0119 0.0909
Echinococcus multilocularis mitogen activated protein kinase 3 0.0046 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Onchocerca volvulus 0.0102 0.0119 0.174
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0075 0.0075
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.002 0 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Chlamydia trachomatis UDP-3-O-acylglucosamine N-acyltransferase 0.0033 0.002 1
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0034 0.0022 0.0185
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0067 0.0068 0.0067
Schistosoma mansoni coup transcription factor 0.0045 0.0037 0.0277
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0019 0.1354
Loa Loa (eye worm) dynactin 5 0.0033 0.002 0.0172
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0083 0.0092 0.0835
Brugia malayi MH1 domain containing protein 0.0029 0.0015 0.0125
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0026 0.001 0.0083
Schistosoma mansoni hypothetical protein 0.0835 0.117 0.9013
Onchocerca volvulus 0.0184 0.0236 0.3472
Brugia malayi hypothetical protein 0.0492 0.0678 0.6215
Brugia malayi G-protein coupled receptor 0.0102 0.0119 0.1082
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0009 0.0075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0067 0.0507
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0077 0.0588
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0029 0.0014 0.0347
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.012 0.3049
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0045 0.0037 0.033
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0021 0.0003 0.0002
Brugia malayi tailless protein 0.0021 0.0003 0.0017
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0024 0.0006 0.0022
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0109 0.0129 0.0438
Plasmodium falciparum mannose-1-phosphate guanyltransferase, putative 0.0034 0.0022 0.1593
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0084 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.012 0.3251
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0102 0.0119 0.1082
Onchocerca volvulus 0.0021 0.0003 0.0028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.001 0.0678
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Entamoeba histolytica serine acetyltransferase 1 0.0033 0.002 0.1449
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.005 0.1354
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0019 0.0495
Onchocerca volvulus 0.0102 0.0119 0.174
Echinococcus granulosus neutral alpha glucosidase AB 0.0033 0.0019 0.0064
Echinococcus granulosus PHD finger protein rhinoceros 0.0052 0.0046 0.0157
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0055 0.0499
Echinococcus multilocularis tissue type plasminogen activator 0.006 0.0058 0.0086
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0078 0.0084 0.6219
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.0119 0.0909
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.0074 0.0079 0.0079
Trypanosoma brucei nucleotidyl transferase, putative 0.0034 0.0022 0.0537
Schistosoma mansoni hypothetical protein 0.0078 0.0084 0.0641
Echinococcus granulosus sex peptide receptor 0.0102 0.0119 0.0402
Onchocerca volvulus 0.0028 0.0012 0.0163
Schistosoma mansoni growth hormone secretagogue receptor 0.0102 0.0119 0.0909
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0103 0.012 0.0405
Echinococcus multilocularis mitogen activated protein kinase 0.0046 0.0038 0.0057
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0002 0.0087
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0011
Leishmania major alpha glucosidase II subunit, putative 0.0033 0.0019 0.0464
Brugia malayi AMP-binding enzyme family protein 0.0026 0.001 0.0083
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0019 0.0495
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0069 0.0071 0.007
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0003 0.0017
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0103 0.012 0.0178
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus multilocularis thioredoxin glutathione reductase 0.003 0.0015 0.0022
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0021 0.0032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0072 0.0075 0.0075
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0033 0.002 0.0019
Schistosoma mansoni RAR-like nuclear receptor 0.0045 0.0037 0.0277
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0102 0.0119 0.0909
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0103 0.012 0.0916
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0102 0.0119 0.0909
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0412 0.0563 0.4759
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0021 0.0021
Schistosoma mansoni ap endonuclease 0.0039 0.0028 0.0206
Schistosoma mansoni smad 0.0024 0.0006 0.0043
Echinococcus granulosus tissue type plasminogen activator 0.006 0.0058 0.0196
Brugia malayi MH2 domain containing protein 0.0053 0.0049 0.0437
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0103 0.012 0.0405
Echinococcus granulosus g-protein coupled receptor 0.0102 0.0119 0.0402
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Schistosoma mansoni hypothetical protein 0.0052 0.0046 0.035
Onchocerca volvulus 0.0021 0.0003 0.0028
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0113 0.0135 0.3658
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0102 0.0119 0.0909
Loa Loa (eye worm) RNA binding protein 0.0073 0.0077 0.0653
Brugia malayi RE15519p 0.0102 0.0119 0.1082
Schistosoma mansoni inositol monophosphatase 0.0069 0.0071 0.0542
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2081 0.2957 0.4383
Schistosoma mansoni Smad4 0.0024 0.0006 0.0043
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0004 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0134 0.0684
Loa Loa (eye worm) hypothetical protein 0.0344 0.0465 0.393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Loa Loa (eye worm) hypothetical protein 0.0142 0.0176 0.1486
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0069 0.0071 0.036
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0077 0.0115
Toxoplasma gondii cytochrome p450 superfamily protein 0.1382 0.1954 1
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.8892
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0045 0.0037 0.033
Loa Loa (eye worm) hypothetical protein 0.013 0.0159 0.1346
Brugia malayi larval opioid receptor 0.0102 0.0119 0.1082
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0103 0.012 0.0178
Loa Loa (eye worm) hypothetical protein 0.0025 0.0008 0.0069
Echinococcus granulosus enteropeptidase 0.0037 0.0025 0.0085
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.004 0.0576
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.0119 0.0176
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0037 0.0025 0.0085
Plasmodium falciparum phd finger protein, putative 0.0052 0.0046 0.3421
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0077 0.0083 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0103 0.012 0.3049
Brugia malayi neuropeptide F receptor 0.0102 0.0119 0.1082
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0103 0.012 0.3049
Schistosoma mansoni smad1 5 8 and 0.0053 0.0049 0.0367
Brugia malayi hypothetical protein 0.0024 0.0006 0.0051
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0072 0.0075 0.068
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.001 0.001
Echinococcus multilocularis cpg binding protein 0.0061 0.0061 0.009
Onchocerca volvulus 0.0058 0.0055 0.0803
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus multilocularis lamin dm0 0.0025 0.0009 0.0013
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Schistosoma mansoni hypothetical protein 0.003 0.0016 0.0113
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0046 0.0038 0.0959
Chlamydia trachomatis acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase 0.0033 0.002 1
Entamoeba histolytica acetyltransferase, putative 0.0033 0.002 0.1449
Brugia malayi Serotonin receptor 0.0102 0.0119 0.1082
Plasmodium vivax SET domain protein, putative 0.0036 0.0024 0.1726
Toxoplasma gondii hypothetical protein 0.0084 0.0093 0.0469
Schistosoma mansoni lamin 0.0025 0.0009 0.0061
Trypanosoma brucei protein kinase, putative 0.0046 0.0038 0.0959
Plasmodium falciparum phosphodiesterase delta, putative 0.0103 0.012 0.8892
Loa Loa (eye worm) trypsin family protein 0.0037 0.0025 0.0212
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0844 0.1183 0.4002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0037 0.0055
Echinococcus multilocularis thyroid hormone receptor alpha 0.0045 0.0037 0.0055
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0154 0.0193 0.0287
Brugia malayi MH1 domain containing protein 0.0029 0.0015 0.0125
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0024 0.0175
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Echinococcus granulosus neuropeptide receptor A26 0.0102 0.0119 0.0402
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.001 0.0233
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0021 0.0104
Mycobacterium ulcerans hypothetical protein 0.0154 0.0193 0.0192
Schistosoma mansoni hypothetical protein 0.013 0.0159 0.1221
Echinococcus multilocularis CREB binding protein 0.0063 0.0062 0.0092
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0037 0.0125
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0034 0.0022 0.0021
Echinococcus granulosus cpg binding protein 0.0061 0.0061 0.0205
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0844 0.1183 0.9113
Brugia malayi hypothetical protein 0.0078 0.0084 0.0763
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0028 0.0012 0.0041
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0045 0.0037 0.0125
Brugia malayi AKH receptor 0.0102 0.0119 0.1082
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.002 0.053
Onchocerca volvulus 0.0037 0.0025 0.0357
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Onchocerca volvulus Serine\/threonine kinase homolog 0.0109 0.0129 0.1896
Echinococcus granulosus somatostatin receptor 0.0102 0.0119 0.0402
Trypanosoma cruzi PAB1-binding protein , putative 0.0062 0.0061 0.1539
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0003 0.0041
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0103 0.012 0.0916
Onchocerca volvulus 0.0102 0.0119 0.174
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.6992 1 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.0119 0.0176
Brugia malayi hypothetical protein 0.0033 0.002 0.0178
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0077 0.07
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0019 0.0495
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0031 0.0777
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Giardia lamblia Rab geranylgeranyltransferase 0.0113 0.0135 0.1131
Loa Loa (eye worm) glutathione reductase 0.0029 0.0014 0.0122
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0028 0.073
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.0119 0.1004
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0067 0.0507
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0003 0.0008
Echinococcus granulosus steroid dehydrogenase 0.002 0.0001 0.0003
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0021 0.0003 0.1022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0083 0.0092 0.0701
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Trypanosoma brucei PAB1-binding protein , putative 0.0062 0.0061 0.1539
Plasmodium vivax thioredoxin reductase, putative 0.0029 0.0014 0.1041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0037 0.0025 0.0085
Brugia malayi RNA binding protein 0.0073 0.0077 0.07
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Trichomonas vaginalis mannose-1-phosphate guanyltransferase, putative 0.0033 0.002 0.053
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0102 0.0119 0.0176
Leishmania major hypothetical protein, conserved 0.0033 0.002 0.0497
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0034 0.0022 0.0032
Toxoplasma gondii LsmAD domain-containing protein 0.0062 0.0061 0.0307
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0102 0.0119 0.0909
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.002 0.0497
Echinococcus multilocularis neuropeptide receptor 0.0102 0.0119 0.0176
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0003 0.0017
Entamoeba histolytica acetyltransferase, putative 0.0033 0.002 0.1449
Schistosoma mansoni gdp-mannose pyrophosphorylase b isoform 2 0.0034 0.0022 0.0161
Onchocerca volvulus 0.0102 0.0119 0.174
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0045 0.0037 0.0125
Brugia malayi Latrophilin receptor protein 2 0.013 0.0159 0.1453
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.0119 0.1004
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0072 0.0075 0.0111
Loa Loa (eye worm) Smad1 0.0053 0.0049 0.0411
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0154 0.0193 0.1483
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0037 0.0277
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0103 0.012 0.3049
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0742 0.1036 0.1536
Loa Loa (eye worm) hypothetical protein 0.002 0 0.0004
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0067 0.0068 0.0068
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0103 0.012 0.0178
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0037 0.033
Schistosoma mansoni alpha glucosidase 0.0033 0.0019 0.014
Brugia malayi hypothetical protein 0.0062 0.0061 0.055
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0045 0.0037 0.0312
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0103 0.012 0.1012
Onchocerca volvulus 0.0102 0.0119 0.174
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0033 0.002 0.1449
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0003 0.0028
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Brugia malayi Serine carboxypeptidase S28 family protein 0.007 0.0073 0.0658
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0025 0.0186
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0055
Echinococcus multilocularis PHD finger protein rhinoceros 0.0052 0.0046 0.0069
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0024 0.0006 0.0081
Brugia malayi hypothetical protein 0.0102 0.0119 0.1082
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0119 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.002 0.0172
Loa Loa (eye worm) runx1 0.0043 0.0034 0.0289
Schistosoma mansoni opsin-like receptor 0.0102 0.0119 0.0909
Entamoeba histolytica ankyrin, putative 0.0033 0.002 0.1449
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.007 0.0073 0.0108
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0055
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0046 0.0038 0.0959
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0044 0.1107
Schistosoma mansoni neuropeptide f receptor 76f 0.0102 0.0119 0.0909
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0071 0.1923
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4723 0.6746 1
Echinococcus granulosus mothers against decapentaplegic 2 0.0024 0.0006 0.0022
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Echinococcus multilocularis mothers against decapentaplegic 2 0.0024 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0412 0.0563 0.4759
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.002 0.0497
Schistosoma mansoni dynactin subunit P25 0.0033 0.002 0.0149
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0003 0.001
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0084 0.0641
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0844 0.1183 0.1754
Brugia malayi intermediate filament protein 0.0025 0.0009 0.0072
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0029 0.0014 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.002 0.0497
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0001 0.0033
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0003 0.0015
Echinococcus granulosus alpha 1A adrenergic receptor 0.0102 0.0119 0.0402
Loa Loa (eye worm) hypothetical protein 0.0113 0.0135 0.1138
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0102 0.0119 0.0909
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Schistosoma mansoni biogenic amine receptor 0.0102 0.0119 0.0909
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0113 0.0135 0.3658
Onchocerca volvulus 0.0037 0.0025 0.0357
Entamoeba histolytica serine acetyltransferase, putative 0.0033 0.002 0.1449
Brugia malayi Hemopexin family protein 0.003 0.0016 0.0134
Echinococcus granulosus lamin dm0 0.0025 0.0009 0.003
Loa Loa (eye worm) thioredoxin reductase 0.0029 0.0014 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.012 0.3251
Leishmania major hypothetical protein, conserved 0.0033 0.002 0.0497
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Leishmania major cAMP-specific phosphodiesterase, putative 0.0103 0.012 0.3049
Echinococcus multilocularis inositol monophosphatase 1 0.0069 0.0071 0.0106
Echinococcus granulosus transcription factor Dp 1 0.0048 0.0042 0.0141
Loa Loa (eye worm) hypothetical protein 0.0052 0.0046 0.0392
Onchocerca volvulus 0.0102 0.0119 0.174
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Echinococcus granulosus g protein coupled receptor 0.0102 0.0119 0.0402
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus granulosus intermediate filament protein 0.0025 0.0009 0.003
Echinococcus granulosus mannose 1 phosphate guanyltransferase 0.0034 0.0022 0.0074
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0024 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0037 0.0125
Echinococcus multilocularis lysosomal alpha glucosidase 0.0147 0.0183 0.0271
Loa Loa (eye worm) matrixin family protein 0.0051 0.0046 0.0389
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0004 0.0034
Schistosoma mansoni opsin-like receptor 0.0102 0.0119 0.0909
Trypanosoma brucei hypothetical protein, conserved 0.0103 0.012 0.3049
Onchocerca volvulus 0.036 0.0488 0.7193
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0102 0.0119 0.1082
Trichomonas vaginalis inositol monophosphatase, putative 0.0069 0.0071 0.1923
Echinococcus multilocularis ecdysone induced protein 78C 0.0045 0.0037 0.0055
Brugia malayi neuropeptide F receptor 0.0102 0.0119 0.1082
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0001 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.0062 0.0061 0.4505
Schistosoma mansoni aldehyde dehydrogenase 0.0223 0.0292 0.2242
Schistosoma mansoni aldehyde dehydrogenase 0.0223 0.0292 0.2242
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Brugia malayi nuclear hormone receptor 0.0045 0.0037 0.033
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0212
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.007 0.0073 0.0553
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0102 0.0119 0.1082
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0046 0.0038 0.0959
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0003 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0119 0.0402
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.001 0.0009
Mycobacterium ulcerans hypothetical protein 0.0033 0.002 0.002
Brugia malayi MH2 domain containing protein 0.0024 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.008
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0028 0.2024
Plasmodium vivax glutathione reductase, putative 0.0029 0.0014 0.1041
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0103 0.012 0.109
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0062 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0055
Brugia malayi Thioredoxin reductase 0.0029 0.0014 0.0124
Echinococcus granulosus tm gpcr rhodopsin 0.2081 0.2957 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0084 0.0093 0.2507
Echinococcus multilocularis neuropeptide receptor 0.0102 0.0119 0.0176
Schistosoma mansoni hypothetical protein 0.006 0.0058 0.044
Schistosoma mansoni kinase 0.0056 0.0052 0.0397
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0045 0.0037 0.0055
Onchocerca volvulus 0.0025 0.0009 0.0116
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.0119 0.0402
Schistosoma mansoni zinc finger protein 0.0021 0.0003 0.0015
Plasmodium vivax hypothetical protein, conserved 0.002 0.0001 0.0033
Loa Loa (eye worm) melatonin receptor type 1A 0.0102 0.0119 0.1004
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0844 0.1183 0.4002
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0103 0.012 0.3049
Brugia malayi N-terminal motif family protein 0.0142 0.0176 0.1604
Mycobacterium tuberculosis Probable dehydrogenase 0.0067 0.0068 0.0068
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0742 0.1036 0.8754
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0001 0.0003
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0103 0.012 0.3049
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.017 0.4347
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0014 0.0347
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Trypanosoma brucei glucosidase, putative 0.0033 0.0019 0.0464
Loa Loa (eye worm) TK/ROR protein kinase 0.006 0.0058 0.0491
Toxoplasma gondii eukaryotic initiation factor 2B epsilon subunit, putative 0.0033 0.002 0.0099
Schistosoma mansoni biogenic amine receptor 0.0102 0.0119 0.0909
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0006 0.0055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.0119 0.0176
Mycobacterium leprae PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) 0.0033 0.002 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0029 0.0014 0.037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.006 0.0058 0.0491
Mycobacterium ulcerans hydrolase 0.0026 0.0009 0.0009
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0102 0.0119 0.0402
Brugia malayi nuclear receptor NHR-67 0.0021 0.0003 0.0017
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0021 0.0032
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0028 0.0685
Onchocerca volvulus 0.0396 0.0541 0.7971
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus granulosus transmembrane protease serine 3 0.0037 0.0025 0.0085
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.013 0.0159 0.1453
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0025 0.0186
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0103 0.012 0.109
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0028 0.073
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0067 0.0068 0.0068
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0025 0.0186
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0024 0.021
Schistosoma mansoni hypothetical protein 0.0033 0.002 0.0149
Schistosoma mansoni adenoreceptor 0.0102 0.0119 0.0909
Echinococcus multilocularis microtubule associated protein 2 0.0827 0.1159 0.1718
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0014 0.0347
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0045 0.0037 0.0312
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.013 0.0159 0.0539
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.012 0.3049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0028 0.0685
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0037 0.0025 0.0222
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0056 0.0471
Schistosoma mansoni hypothetical protein 0.0102 0.0119 0.0909
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0003 0.0015
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.8892
Echinococcus granulosus mitogen activated protein kinase 3 0.0046 0.0038 0.013
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0925 0.1298 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus multilocularis mothers against decapentaplegic 5 0.0053 0.0049 0.0072
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0113 0.0135 0.1226
Onchocerca volvulus 0.0102 0.0119 0.174
Echinococcus granulosus smad 0.0053 0.0049 0.0164
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0003 0.0015
Echinococcus granulosus survival motor neuron protein 1 0.0283 0.0379 0.1282
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0021 0.0522
Brugia malayi jmjC domain containing protein 0.0169 0.0215 0.1961
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Mycobacterium tuberculosis Probable reductase 0.0067 0.0068 0.0068
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0009 0.0075
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0037 0.0025 0.0186
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Schistosoma mansoni hypothetical protein 0.0028 0.0012 0.0086
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0083 0.0092 0.0311
Brugia malayi sulfakinin receptor protein 0.0102 0.0119 0.1082
Loa Loa (eye worm) hypothetical protein 0.0396 0.0541 0.4572
Echinococcus granulosus tar DNA binding protein 0.0073 0.0077 0.0261
Mycobacterium tuberculosis Possible transferase 0.0033 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0046 0.3421
Brugia malayi PHD-finger family protein 0.0052 0.0046 0.0417
Echinococcus multilocularis serotonin receptor 0.0102 0.0119 0.0176
Echinococcus multilocularis G protein coupled receptor 139 0.0102 0.0119 0.0176
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0113 0.0135 0.3658
Echinococcus granulosus dnaJ subfamily B 0.0395 0.0539 0.1823
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0028 0.0027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0003 0.0004
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0168 0.0213 0.1638
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0029 0.0014 0.0347
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0008
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0103 0.012 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Schistosoma mansoni biogenic amine receptor 0.0102 0.0119 0.0909
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0103 0.012 0.0405
Treponema pallidum licC protein (licC) 0.1214 0.1714 1
Echinococcus multilocularis allatostatin A receptor 0.0102 0.0119 0.0176
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0286
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.0036 0.027
Echinococcus multilocularis FTZ F1 alpha 0.0045 0.0037 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0119 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0037 0.033
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0019 0.1354
Brugia malayi hypothetical protein 0.0021 0.0003 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0119 0.0909
Schistosoma mansoni hypothetical protein 0.013 0.0159 0.1221
Plasmodium vivax hypothetical protein, conserved 0.002 0.0002 0.0087
Mycobacterium ulcerans short chain dehydrogenase 0.1176 0.1659 0.1659
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0046 0.0038 0.0959
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0154 0.0193 0.1483
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0014 0.0347
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.0119 0.1004
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Echinococcus granulosus hypothetical protein 0.0102 0.0119 0.0402
Brugia malayi Steroid receptor seven-up type 2 0.0045 0.0037 0.033
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0003 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0003 0.0002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0412 0.0563 0.5157
Echinococcus granulosus thioredoxin glutathione reductase 0.003 0.0015 0.0051
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Mycobacterium ulcerans hypothetical protein 0.1214 0.1714 0.1713
Mycobacterium ulcerans aldehyde dehydrogenase 0.0223 0.0292 0.0291
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0062 0.0061 0.0515
Brugia malayi MAP kinase sur-1 0.0046 0.0038 0.0343
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.001 0.0233
Toxoplasma gondii hypothetical protein 0.0033 0.002 0.0099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.012 0.0608
Loa Loa (eye worm) hypothetical protein 0.0283 0.0379 0.3202
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0312
Echinococcus multilocularis mothers against decapentaplegic 6 0.0024 0.0006 0.001
Schistosoma mansoni smad1 5 8 and 0.0053 0.0049 0.0367
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0031 0.0777
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0019 0.0495
Onchocerca volvulus 0.0058 0.0056 0.0809
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Schistosoma mansoni amine GPCR 0.0102 0.0119 0.0909
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0001 0.0001
Brugia malayi glutathione reductase 0.0029 0.0014 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.012 0.3049
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0029 0.0014 0.0124
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0113 0.0135 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.0119 0.0909
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.0119 0.0402
Echinococcus multilocularis neuropeptide receptor A26 0.0102 0.0119 0.0176
Echinococcus multilocularis g-protein coupled receptor 0.0102 0.0119 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0014 0.0347
Loa Loa (eye worm) hypothetical protein 0.0033 0.002 0.0172
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0212
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0003
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0072 0.0075 0.1901
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0075
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.007 0.0073 0.0246
Echinococcus granulosus L aminoadipate semialdehyde 0.0075 0.008 0.0269
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0084
Schistosoma mansoni intermediate filament proteins 0.0025 0.0009 0.0061
Schistosoma mansoni hypothetical protein 0.0037 0.0025 0.0186
Echinococcus granulosus FTZ F1 alpha 0.0045 0.0037 0.0125
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0029 0.0014 0.0122
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0037 0.0277
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0038 0.1023
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0103 0.012 0.3251
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Brugia malayi hypothetical protein 0.0033 0.002 0.0178
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0083 0.0092 0.2334
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0009 0.0009
Giardia lamblia PHD finger protein 15 0.0052 0.0046 0.0384
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.013 0.0159 0.0539
Loa Loa (eye worm) hypothetical protein 0.0075 0.008 0.0672
Loa Loa (eye worm) hypothetical protein 0.0102 0.0119 0.1004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0033 0.0019 0.0166
Brugia malayi ecdysone receptor 0.0021 0.0003 0.0017
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0021 0.1551
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0129 0.3514
Brugia malayi Smad1 0.0053 0.0049 0.0437
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0024
Schistosoma mansoni hypothetical protein 0.0102 0.0119 0.0909
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0045 0.0037 0.0277
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0001 0.0003
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0102 0.0119 0.1004
Echinococcus multilocularis expressed protein 0.0293 0.0393 0.0583
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0025 0.0186
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0045 0.0037 0.0277
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0102 0.0119 0.0176
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0083 0.0092 0.0136
Toxoplasma gondii kringle domain-containing protein 0.006 0.0058 0.0292
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0396 0.0541 0.4162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0119 0.0176
Brugia malayi Trypsin family protein 0.0037 0.0025 0.0222
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0119 0.0176
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0147 0.0183 0.1543
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0571 0.0791 0.6087
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.002 0.0068
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0123
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.002 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.0119 0.0402
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.017 0.4347
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0103 0.012 0.3251
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0083 0.0092 0.2334
Brugia malayi PHD-finger family protein 0.002 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0282 0.0376 0.318
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0103 0.012 0.0405
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0102 0.0119 0.0909
Echinococcus multilocularis lamin 0.0025 0.0009 0.0013
Brugia malayi conserved hypotetical protein 0.0021 0.0003 0.0017
Schistosoma mansoni cpg binding protein 0.0058 0.0056 0.0423
Echinococcus multilocularis survival motor neuron protein 1 0.0283 0.0379 0.0562
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0003
Brugia malayi Kringle domain containing protein 0.006 0.0058 0.0524
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0021 0.0032
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0024 0.008
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0004 0.0028
Schistosoma mansoni Smad4 0.0024 0.0006 0.0043
Loa Loa (eye worm) PHD-finger family protein 0.0052 0.0046 0.0392
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0021 0.018
Onchocerca volvulus 0.0102 0.0119 0.174
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0571 0.0791 0.7245

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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