Detailed information for compound 787064

Basic information

Technical information
  • TDR Targets ID: 787064
  • Name: 3-methyl-N-(4-methylphenyl)-2-(thiophen-2-yls ulfonylamino)butanamide
  • MW: 352.472 | Formula: C16H20N2O3S2
  • H donors: 2 H acceptors: 3 LogP: 3.53 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C(C(=O)Nc1ccc(cc1)C)NS(=O)(=O)c1cccs1)C
  • InChi: 1S/C16H20N2O3S2/c1-11(2)15(18-23(20,21)14-5-4-10-22-14)16(19)17-13-8-6-12(3)7-9-13/h4-11,15,18H,1-3H3,(H,17,19)
  • InChiKey: QWRWQZHAZJFCSR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-methyl-N-(4-methylphenyl)-2-(2-thienylsulfonylamino)butanamide
  • 3-methyl-N-(4-methylphenyl)-2-(2-thienylsulfonylamino)butyramide
  • EU-0056908

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0046 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Brugia malayi celfurPC protein 0.0013 0.0017 0.0075
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.004 0.0209 0.093
Leishmania major lysyl-tRNA synthetase, putative 0.0072 0.0441 0.1991
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0018 0.0053 0.2114
Leishmania major 4-coumarate:coa ligase-like protein 0.0095 0.0601 0.2714
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0069 0.0312
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0013 0.0017 0.0017
Plasmodium falciparum protein kinase 7 0.0916 0.6492 0.6631
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0402 0.3463
Onchocerca volvulus 0.0028 0.0122 0.0915
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0046 0.0249 1
Onchocerca volvulus 0.0046 0.0249 0.1905
Onchocerca volvulus 0.0046 0.0249 0.1905
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0011 0.0001 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0095 0.0601 0.5254
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.006 0.0267
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0261 0.1162
Schistosoma mansoni sugar transporter 0.0046 0.0249 0.0249
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0034 0.0169 0.1489
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0766 0.341
Trichomonas vaginalis glucose transporter, putative 0.0101 0.0643 0.2864
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Trypanosoma cruzi hexose transporter, putative 0.0101 0.0643 0.2907
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0013 0.0017 0.0017
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0312
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0033 0.0033
Brugia malayi Hint module family protein 0.0049 0.0275 0.1223
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0122 0.0945
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0071 0.043 0.3712
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.2214 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.043 0.1913
Loa Loa (eye worm) 63kd antigen 0.0011 0.0001 0.0004
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0122 0.1743
Chlamydia trachomatis threonine--tRNA ligase 0.0018 0.0053 0.1193
Entamoeba histolytica protein kinase, putative 0.0045 0.0243 0.3627
Schistosoma mansoni hypothetical protein 0.0132 0.0867 0.0867
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Plasmodium vivax hexose transporter 0.0324 0.2247 0.2295
Plasmodium vivax sugar transporter, putative 0.0046 0.0249 0.0254
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0033 0.0148
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0033 0.0033
Echinococcus granulosus Furin 1 0.0013 0.0017 0.0017
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Brugia malayi Ets-domain containing protein 0.0071 0.0431 0.1917
Schistosoma mansoni patched 1 0.0045 0.0243 0.0243
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0122 0.0547
Leishmania major hypothetical protein, conserved 0.0016 0.0038 0.0169
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.006 0.0267
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.006 0.006
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.01 0.0637 0.0637
Toxoplasma gondii subtilisin SUB5 0.0013 0.0017 0.0025
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Treponema pallidum glycyl-tRNA synthetase 0.0011 0.0001 0.002
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0122 0.0551
Mycobacterium ulcerans hypothetical protein 0.0168 0.113 1
Trichomonas vaginalis ubiquitin, putative 0.0011 0.0004 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0009 0.0039
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0038 0.0192
Echinococcus multilocularis solute carrier family 22 0.0046 0.0249 0.0249
Loa Loa (eye worm) sugar transporter 0.0046 0.0249 0.111
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0013 0.0017 0.0075
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0069
Brugia malayi MH2 domain containing protein 0.0118 0.0766 0.341
Plasmodium vivax lysine--tRNA ligase, putative 0.0072 0.0441 0.045
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0637 0.2833
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0038 0.0172
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0122 0.0543
Toxoplasma gondii sugar transporter ST2 0.0046 0.0249 0.0383
Brugia malayi hypothetical protein 0.0046 0.0249 0.111
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0053 0.0054
Onchocerca volvulus 0.0046 0.0249 0.1905
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0243 0.0243
Echinococcus multilocularis GPCR, family 2 0.0015 0.0033 0.0033
Trypanosoma brucei glucose transporter 2A 0.0101 0.0643 0.2904
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0017 0.0075
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0122 0.0945
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0122 0.0124
Entamoeba histolytica protein kinase, putative 0.01 0.0637 0.9508
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0072 0.0441 0.1994
Plasmodium falciparum small ubiquitin-related modifier 0.0032 0.0155 0.0158
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0053 0.0238
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0111 0.0111
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0016 0.0038 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Plasmodium falciparum calcium-dependent protein kinase 1 0.01 0.0637 0.065
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0033 0.0148
Chlamydia trachomatis proline--tRNA ligase 0.0034 0.0169 0.3815
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0272 0.1212
Leishmania major glucose transporter, lmgt1 0.0101 0.0643 0.2904
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Plasmodium vivax subtilisin-like serine protease, putative 0.0013 0.0017 0.0016
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0072 0.0441 0.1991
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.006 0.0091
Plasmodium falciparum hexose transporter 0.0324 0.2247 0.2295
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0046 0.0249 0.2203
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0011 0.0001 0.0004
Echinococcus granulosus expressed conserved protein 0.0098 0.0624 0.0624
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Echinococcus granulosus lysyl tRNA synthetase 0.0072 0.0441 0.0441
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Onchocerca volvulus 0.0047 0.0261 0.1995
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0122 0.0547
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Schistosoma mansoni ets-related 0.0215 0.1465 0.1465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus granulosus dna polymerase eta 0.002 0.0069 0.0069
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0013 0.0017 0.0017
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0013 0.0017 0.0142
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0011 0.0001 0.0001
Plasmodium falciparum protein kinase 6 0.1377 0.979 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0024 0.0103
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0013 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0026 0.0111 0.1659
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0053 0.0466
Giardia lamblia Glycyl-tRNA synthetase 0.0018 0.0053 0.0849
Leishmania major subtilisin-like serine peptidase 0.0013 0.0017 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0122 0.0187
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0038 0.0169
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0053 0.0241
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0095 0.0601 0.9692
Giardia lamblia Hexose transporter 0.0046 0.0249 0.4016
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Brugia malayi hypothetical protein 0.0011 0.0004 0.0018
Brugia malayi Cam kinase protein 1 0.01 0.0637 0.2833
Echinococcus multilocularis Small ubiquitin modifier 2 0.0032 0.0155 0.0155
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0053 0.0329
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.006 0.027
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0053 0.0238
Loa Loa (eye worm) hypothetical protein 0.0095 0.0601 0.2676
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0122 0.0547
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0011 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0071 0.043 0.1913
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0045 0.0243 0.0243
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Schistosoma mansoni glucose transport protein 0.0324 0.2247 0.2247
Loa Loa (eye worm) hypothetical protein 0.0097 0.062 0.2759
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0249 0.111
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0033
Toxoplasma gondii subtilisin SUB12 0.0013 0.0017 0.0025
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.2214 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0104 0.067 1
Leishmania major DNA polymerase kappa, putative 0.002 0.0069 0.0308
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0446 0.0446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0324 0.2247 0.2247
Toxoplasma gondii anticodon binding domain-containing protein 0.0011 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0095 0.0601 0.2676
Trypanosoma brucei unspecified product 0.002 0.0069 0.0308
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis glucose transporter, putative 0.0046 0.0249 0.111
Schistosoma mansoni threonyl-tRNA synthetase 0.0011 0.0001 0.0001
Schistosoma mansoni protein kinase 0.01 0.0637 0.0637
Toxoplasma gondii sugar transporter ST1 0.0046 0.0249 0.0383
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0039
Leishmania major protein kinase, putative 0.01 0.0637 0.2873
Brugia malayi neuroendocrine convertase 1 precursor 0.0013 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.0307
Loa Loa (eye worm) hypothetical protein 0.0231 0.1582 0.704
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0122 0.0551
Brugia malayi proprotein convertase 2 0.0013 0.0017 0.0075
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0069 0.0469
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0431 0.0431
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0046 0.0249 0.2203
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0012 0.0009 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0017 0.0075
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0045 0.0243 0.0243
Trypanosoma brucei glucose transporter 1E 0.0101 0.0643 0.2904
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.006 0.027
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.006 0.006
Trichomonas vaginalis sugar transporter, putative 0.0101 0.0643 0.2864
Brugia malayi Fli-1 protein 0.0215 0.1465 0.6521
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0097 0.062 0.2759
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0046 0.0249 0.0249
Schistosoma mansoni glucose transport protein 0.0324 0.2247 0.2247
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0053 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0122 0.0543
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0122 0.0543
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0053 0.0238
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0053 0.0054
Brugia malayi Ets-domain containing protein 0.0071 0.0431 0.1917
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Plasmodium vivax subtilisin-like protease 2, putative 0.0013 0.0017 0.0016
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0013 0.0017 0.0076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.1007 0.4549
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Echinococcus multilocularis calcium dependent protein kinase 0.0093 0.059 0.059
Onchocerca volvulus 0.0028 0.0122 0.0915
Mycobacterium ulcerans hypothetical protein 0.0016 0.0038 0.0331
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.006 0.0267
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0069 0.1031
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0111 0.017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0011 0.0001 0.0012
Echinococcus multilocularis Niemann Pick C1 protein 0.0149 0.099 0.099
Echinococcus multilocularis protein dispatched 1 0.0051 0.0288 0.0288
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Echinococcus granulosus calcium dependent protein kinase 0.0093 0.059 0.059
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0013 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0039
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.1007 0.4547
Brugia malayi Sugar transporter family protein 0.0046 0.0249 0.111
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0053 0.0053
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Trypanosoma brucei THT1 - hexose transporter, putative 0.0101 0.0643 0.2904
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0061 0.0363 0.5744
Entamoeba histolytica acyl-CoA synthetase, putative 0.0095 0.0601 0.8982
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0095 0.0601 0.9692
Echinococcus granulosus Sugar transporter ERD6 protein 0.0046 0.0249 0.0249
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0122 0.0547
Leishmania major histidyl-tRNA synthetase, putative 0.0011 0.0001 0.0002
Echinococcus multilocularis Niemann Pick C1 protein 0.0104 0.067 0.067
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.01 0.0637 0.098
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0049 0.0272 0.1212
Loa Loa (eye worm) hypothetical protein 0.0191 0.1292 0.5751
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0072 0.0441 0.3904
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.1582 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0001 0.0001
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0013 0.0017 0.0017
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0013 0.0017 0.0142
Schistosoma mansoni protein kinase 0.01 0.0637 0.0637
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0308
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Onchocerca volvulus 0.0046 0.0249 0.1905
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0122 0.0187
Giardia lamblia Sugar-proton symporter 0.0046 0.0249 0.4016
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.01 0.0637 0.065
Brugia malayi lysyl-tRNA synthetase 0.0072 0.0441 0.1965
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.0307
Loa Loa (eye worm) hypothetical protein 0.0071 0.043 0.1913
Echinococcus granulosus dna polymerase kappa 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0095 0.0601 0.2676
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0095 0.0601 0.5321
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0113 0.0736 0.3322
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0243 0.0243
Onchocerca volvulus 0.0046 0.0249 0.1905
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0122 0.0945
Brugia malayi Sugar transporter family protein 0.0324 0.2247 1
Trypanosoma cruzi hexose transporter, putative 0.0101 0.0643 0.2907
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0011 0.0001 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.006 0.0266
Schistosoma mansoni site-1 peptidase (S08 family) 0.0013 0.0017 0.0017
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0095 0.0601 0.5321
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0122 0.0122
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0072 0.0441 0.1965
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0111 0.0494
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0001 0.0001
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0122 0.1073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0001 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0446 0.0446
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0312
Loa Loa (eye worm) hypothetical protein 0.0033 0.0162 0.072
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0111 0.0498
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0053 0.0053
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0011 0.0001 0.0001
Echinococcus multilocularis membrane bound transcription factor site 1 0.0013 0.0017 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0402 0.3463
Echinococcus multilocularis Furin 1 0.0013 0.0017 0.0017
Echinococcus granulosus solute carrier family 22 0.0046 0.0249 0.0249
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0011 0.0001 0.0005
Onchocerca volvulus 0.0046 0.0249 0.1905
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0053 0.0238
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0122 0.0543
Echinococcus granulosus ubiquitin 0.0011 0.0004 0.0004
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0249 0.111
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0018 0.0053 0.2114
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Brugia malayi hypothetical protein 0.0046 0.0249 0.111
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0038 0.017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0013 0.0017 0.0072
Leishmania major 4-coumarate:coa ligase-like protein 0.0095 0.0601 0.2714
Loa Loa (eye worm) hypothetical protein 0.0049 0.0275 0.1223
Loa Loa (eye worm) hypothetical protein 0.0071 0.043 0.1913
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0643 0.2864
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0069 0.0307
Leishmania major small ubiquitin protein, putative 0.0032 0.0155 0.0698
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.006 0.0267
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0122 0.0945
Echinococcus granulosus Niemann Pick C1 protein 0.0104 0.067 0.067
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0095 0.0601 0.5254
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0122 0.0124
Entamoeba histolytica protein kinase, putative 0.01 0.0637 0.9508
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0111 0.0111
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0315 0.1424
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0106 0.0681 0.0681
Entamoeba histolytica hypothetical protein 0.0072 0.0441 0.6593
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0011 0.0001 0.0001
Plasmodium vivax small ubiquitin-related modifier, putative 0.0032 0.0155 0.0158
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0069 0.0307
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0122 0.0945
Echinococcus granulosus furin 0.0013 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0038 0.0172
Loa Loa (eye worm) hypothetical protein 0.0097 0.062 0.2759
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0011 0.0001 0.0005
Trichomonas vaginalis myo-inositol transporter, putative 0.0046 0.0249 0.111
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0308
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0122 0.0551
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0075
Schistosoma mansoni protein kinase 0.01 0.0637 0.0637
Onchocerca volvulus 0.0028 0.0122 0.0915
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0113 0.0736 0.1132
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0033 0.0033
Schistosoma mansoni site-1 peptidase (S08 family) 0.0013 0.0017 0.0017
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.006 0.0266
Echinococcus granulosus Niemann Pick C1 protein 0.0149 0.099 0.099
Toxoplasma gondii subtilisin SUB1 0.0188 0.1271 0.1957
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0122 0.0945
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0524 0.3681 0.5669
Schistosoma mansoni microtubule-associated protein tau 0.1406 1 1
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0013 0.0017 0.0075
Plasmodium falciparum subtilisin-like protease 1 0.0188 0.1271 0.1297
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0249 0.111
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0011 0.0001 0.0017
Toxoplasma gondii lysine-tRNA ligase 0.0072 0.0441 0.0679
Trypanosoma brucei histidyl-tRNA synthetase 0.0011 0.0001 0.0002
Brugia malayi hypothetical protein 0.0231 0.1582 0.704
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0249 0.111
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0072 0.0441 0.3904
Toxoplasma gondii subtilisin SUB9 0.0013 0.0017 0.0025
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0046 0.0249 0.2091
Plasmodium falciparum subtilisin-like protease 3 0.0013 0.0017 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0122 0.0945
Onchocerca volvulus 0.0046 0.0249 0.1905
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0113 0.0736 0.332
Trypanosoma brucei mitochondrial DNA polymerase beta 0.032 0.2214 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0122 0.0945
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.006 0.0267
Leishmania major glucose transporter, lmgt2 0.0101 0.0643 0.2904
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0038 0.017
Echinococcus multilocularis histidyl tRNA synthetase 0.0011 0.0001 0.0001
Plasmodium falciparum subtilisin-like protease 2 0.0013 0.0017 0.0016
Trypanosoma brucei THT1 - hexose transporter, putative 0.0101 0.0643 0.2904
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0245 0.1106
Treponema pallidum threonyl-tRNA synthetase 0.0018 0.0053 0.3127
Trypanosoma brucei sugar transporter, putative 0.0046 0.0249 0.1123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0249 0.111
Loa Loa (eye worm) hypothetical protein 0.0104 0.067 0.298
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Loa Loa (eye worm) hypothetical protein 0.0049 0.0275 0.1223
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0122 0.1073
Leishmania major myo-inositol/proton symporter (MIT) 0.0046 0.0249 0.1123
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0097 0.062 0.062
Leishmania major mitochondrial DNA polymerase beta 0.032 0.2214 1
Trypanosoma cruzi small ubiquitin protein, putative 0.0032 0.0155 0.0702
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0272 0.1212
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0073 0.0446 0.0446
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0012 0.0009 0.0012
Echinococcus multilocularis hedgehog 0.0181 0.122 0.122
Brugia malayi AMP-binding enzyme family protein 0.0095 0.0601 0.2676
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.01 0.0637 0.2873
Trichomonas vaginalis sugar transport protein, putative 0.0046 0.0249 0.111
Onchocerca volvulus 0.0046 0.0249 0.1905
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0053 0.0053
Onchocerca volvulus 0.0046 0.0249 0.1905
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.006 0.006
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0046 0.0249 0.2091
Brugia malayi Aspartyl-tRNA synthetase 0.0011 0.0001 0.0004
Echinococcus multilocularis 0.0013 0.0017 0.0017
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0069 0.0308
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0046 0.0249 0.1123
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0111 0.0111
Trypanosoma cruzi hexose transporter, putative 0.0046 0.0249 0.1127
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0053 0.0607
Giardia lamblia Threonyl-tRNA synthetase 0.0018 0.0053 0.0849
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0858 0.6075 0.6075
Plasmodium vivax subtilisin-like protease 1 0.0188 0.1271 0.1297
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0148
Toxoplasma gondii subtilisin SUB4 0.0013 0.0017 0.0025
Schistosoma mansoni survival motor neuron protein 0.0047 0.0261 0.0261
Trypanosoma brucei unspecified product 0.0014 0.0024 0.0103
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0071 0.043 0.1913
Brugia malayi major facilitator superfamily protein 0.0046 0.0249 0.111
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0061 0.0363 0.3113
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0122 0.0187
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Entamoeba histolytica acyl-CoA synthetase, putative 0.0095 0.0601 0.8982
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0011 0.0001 0.0012
Toxoplasma gondii subtilisin SUB8 0.0013 0.0017 0.0025
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0122 0.1073
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0033 0.0148
Giardia lamblia Prolyl-tRNA synthetase 0.0097 0.062 1
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0122 0.1743
Loa Loa (eye worm) endoprotease bli-4 0.0013 0.0017 0.0075
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma cruzi hexose transporter, putative 0.0101 0.0643 0.2907
Echinococcus multilocularis neuroendocrine convertase 2 0.0013 0.0017 0.0017
Echinococcus granulosus GPCR family 2 0.0015 0.0033 0.0033
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0046 0.0249 0.0254
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.006 0.0893
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0446 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0017 0.0075
Leishmania major DNA polymerase eta, putative 0.002 0.0069 0.0308
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0272 0.1212
Entamoeba histolytica ubiquitin like protein 0.0032 0.0155 0.232
Trypanosoma cruzi hexose transporter, putative 0.0055 0.0317 0.143
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.2247 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Mycobacterium ulcerans hypothetical protein 0.0095 0.0601 0.5321
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus multilocularis microtubule associated protein 2 0.1406 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0122 0.0543
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0243 0.0243
Echinococcus multilocularis lysyl tRNA synthetase 0.0072 0.0441 0.0441
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Schistosoma mansoni hypothetical protein 0.0047 0.0261 0.0261
Brugia malayi Hint module family protein 0.0049 0.0275 0.1223
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0018 0.0053 0.0797
Brugia malayi Sugar transporter family protein 0.0046 0.0249 0.111
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0122 0.0543
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Loa Loa (eye worm) hypothetical protein 0.01 0.0637 0.2833
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0122 0.1073
Leishmania major glycyl tRNA synthetase, putative 0.0011 0.0001 0.0002
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0095 0.0601 0.2676
Echinococcus granulosus Desert hedgehog protein 0.0181 0.122 0.122
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0053 0.0238
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0072 0.0441 0.704
Leishmania major hypothetical protein, conserved 0.0046 0.0249 0.1123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0097 0.062 0.062
Schistosoma mansoni lysyl-tRNA synthetase 0.0072 0.0441 0.0441
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0055 0.0315 0.1403
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Schistosoma mansoni hypothetical protein 0.0043 0.0232 0.0232
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0097 0.062 0.2759
Echinococcus granulosus neuroendocrine convertase 2 0.0013 0.0017 0.0017
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0038 0.0172
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0113 0.0736 0.332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0402 0.3463
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0122 0.0543
Leishmania major 4-coumarate:coa ligase-like protein 0.0095 0.0601 0.2714
Brugia malayi Subtilase family protein 0.0013 0.0017 0.0075
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0431 0.0431
Trichomonas vaginalis glucose transporter, putative 0.0101 0.0643 0.2864
Schistosoma mansoni furin-1 (S08 family) 0.0013 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0038 0.017
Toxoplasma gondii subtilisin SUB10 0.0013 0.0017 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Chlamydia trachomatis histidine--tRNA ligase 0.0011 0.0001 0.0008
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.006 0.027
Loa Loa (eye worm) hypothetical protein 0.0079 0.0489 0.2177
Echinococcus multilocularis solute carrier family 22 0.0046 0.0249 0.0249
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0053 0.0238
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0238
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0095 0.0601 0.5321
Entamoeba histolytica hypothetical protein 0.0073 0.0446 0.6661
Schistosoma mansoni glucose transporter 0.0046 0.0249 0.0249
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0071 0.043 0.9736
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0038 0.0172
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Giardia lamblia Sentrin 0.0032 0.0155 0.2496
Trypanosoma cruzi small ubiquitin protein, putative 0.0032 0.0155 0.0702
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0069 0.0307
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.006 0.0271
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0097 0.062 0.9259
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0122 0.0122
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0122 0.1073
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0033
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0053 0.0081
Onchocerca volvulus 0.0028 0.0122 0.0915
Toxoplasma gondii subtilisin SUB11 0.0013 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Toxoplasma gondii subtilisin SUB6 0.0013 0.0017 0.0025
Leishmania major glucose transporter, lmgt3 0.0101 0.0643 0.2904
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Echinococcus granulosus membrane bound transcription factor site 1 0.0013 0.0017 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0017 0.0075
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0122 0.1743
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.006 0.0893
Echinococcus granulosus histidyl tRNA synthetase 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus multilocularis protein patched 0.0045 0.0243 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0024 0.0103
Plasmodium vivax acyl-CoA synthetase, putative 0.0071 0.043 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0243 0.1082
Onchocerca volvulus 0.0046 0.0249 0.1905
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Plasmodium falciparum calcium-dependent protein kinase 2 0.01 0.0637 0.065
Treponema pallidum prolyl-tRNA synthetase 0.0034 0.0169 1
Onchocerca volvulus 0.0046 0.0249 0.1905
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0069 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Schistosoma mansoni sugar transporter 0.0046 0.0249 0.0249
Plasmodium falciparum lysine--tRNA ligase 0.0072 0.0441 0.045
Trypanosoma cruzi sugar transporter, putative 0.0046 0.0249 0.1127
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0312
Toxoplasma gondii transporter, major facilitator family protein 0.0046 0.0249 0.0383
Entamoeba histolytica hypothetical protein 0.0073 0.0446 0.6661
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0101 0.0643 0.2864
Toxoplasma gondii protein kinase, putative 0.0916 0.6492 1
Onchocerca volvulus 0.0046 0.0249 0.1905
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0524 0.3681 0.3759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Mycobacterium ulcerans acyl-CoA synthetase 0.0095 0.0601 0.5321
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0111 0.0502
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.01 0.0637 0.065
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0032 0.0155 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.1582 0.1582
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0766 0.341
Loa Loa (eye worm) hypothetical protein 0.0095 0.0601 0.2676
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0001 0.0004
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0013 0.0017 0.0017
Entamoeba histolytica acyl-coA synthetase, putative 0.0095 0.0601 0.8982
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0249 0.111
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0122 0.1073
Echinococcus granulosus General substrate transporter 0.0279 0.192 0.192
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.006 0.0266
Brugia malayi major facilitator superfamily protein 0.0046 0.0249 0.111
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0053 0.0238
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0094 0.0696
Onchocerca volvulus 0.0095 0.0601 0.4637
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0075
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0243 0.0243
Brugia malayi Niemann-Pick C1 protein precursor 0.0104 0.067 0.298
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0604
Echinococcus granulosus solute carrier family 22 0.0046 0.0249 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus multilocularis expressed conserved protein 0.0098 0.0624 0.0624
Mycobacterium tuberculosis Conserved hypothetical protein 0.0168 0.113 1
Plasmodium falciparum acyl-CoA synthetase 0.0071 0.043 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0018
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0604
Plasmodium vivax CDK-related protein kinase 6, putative 0.1377 0.979 1
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0033 0.0033
Giardia lamblia GTOR 0.0019 0.006 0.0953
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0053 0.0053
Brugia malayi hypothetical protein 0.0046 0.0249 0.111
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Trypanosoma brucei subtilisin peptidase 0.0013 0.0017 0.0072
Trypanosoma cruzi hexose transporter 0.0101 0.0643 0.2907
Toxoplasma gondii subtilisin SUB7 0.0013 0.0017 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0024 0.0103
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0122 0.0543
Onchocerca volvulus 0.0046 0.0249 0.1905
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0122 0.1073
Echinococcus granulosus synaptic vesicle 2 protein 0.0046 0.0249 0.0249
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0122 0.1821
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0637 0.2833
Onchocerca volvulus 0.0046 0.0249 0.1905
Schistosoma mansoni gabp alpha 0.0071 0.0431 0.0431
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0155 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0038 0.0354
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.006 0.006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Onchocerca volvulus 0.0046 0.0249 0.1905
Plasmodium falciparum calcium-dependent protein kinase 3 0.01 0.0637 0.065
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.1007 0.4547
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Entamoeba histolytica hypothetical protein 0.0073 0.0446 0.6661
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0018
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.006 0.027
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0191 0.1292 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.01 0.0637 0.2833
Mycobacterium ulcerans acyl-CoA synthetase 0.0095 0.0601 0.5321
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0122 0.0543
Loa Loa (eye worm) subtilase 0.0013 0.0017 0.0075
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0431 0.1917
Giardia lamblia Lysyl-tRNA synthetase 0.0072 0.0441 0.7117
Plasmodium vivax proline--tRNA ligase, putative 0.0113 0.0736 0.075
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0013 0.0017 0.0142
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0045 0.0243 0.0243
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0013 0.0017 0.0017
Loa Loa (eye worm) oxidoreductase 0.0028 0.0122 0.0543
Echinococcus multilocularis solute carrier family 22 0.0046 0.0249 0.0249
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.01 0.0637 0.2833
Loa Loa (eye worm) hypothetical protein 0.0072 0.0441 0.1965
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.006 0.0267
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0402 0.3463
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0249 0.111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Loa Loa (eye worm) hypothetical protein 0.0028 0.0122 0.0543
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0053 0.0081
Echinococcus multilocularis synaptic vesicle 2 protein 0.0046 0.0249 0.0249
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Schistosoma mansoni sugar transporter 0.0046 0.0249 0.0249
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0069 0.0069
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0122 0.0945
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus multilocularis ubiquitin 0.0011 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0111 0.0494
Echinococcus granulosus Small ubiquitin modifier 2 0.0032 0.0155 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0085 0.0382
Entamoeba histolytica protein kinase, putative 0.0045 0.0243 0.3627
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.006 0.0267
Brugia malayi N-terminal motif family protein 0.0191 0.1292 0.5751
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0011 0.0001 0.0003
Toxoplasma gondii small ubiquitin family modifier, putative 0.0032 0.0155 0.0238
Brugia malayi endoprotease bli-4 precursor 0.0013 0.0017 0.0075
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0069 0.0308
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.006 0.0268
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.006 0.027
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0643 0.2864
Toxoplasma gondii hypothetical protein 0.0052 0.0292 0.0449
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0308
Onchocerca volvulus 0.0013 0.0017 0.0099
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0097 0.062 0.062
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0063 0.0377 0.168
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0097 0.062 0.062
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Schistosoma mansoni lysyl-tRNA synthetase 0.0072 0.0441 0.0441
Brugia malayi Ubiquitin-like protein SMT3 0.0032 0.0155 0.0691
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Onchocerca volvulus 0.0046 0.0249 0.1905
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0245 0.1106
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.006 0.0267
Schistosoma mansoni hypothetical protein 0.0033 0.0162 0.0162
Trypanosoma brucei THT1 - hexose transporter, putative 0.0101 0.0643 0.2904
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0085 0.0377
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0013 0.0017 0.0076
Trypanosoma cruzi histidyl-tRNA synthetase 0.0011 0.0001 0.0005
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0097 0.062 0.2759
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.01 0.0637 0.098
Loa Loa (eye worm) proprotein convertase 2 0.0013 0.0017 0.0075
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0001 0.0005
Plasmodium falciparum calcium-dependent protein kinase 4 0.01 0.0637 0.065
Plasmodium vivax calcium-dependent protein kinase, putative 0.01 0.0637 0.065
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.01 0.0637 0.065
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0122 0.0945
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.006 0.0267
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0122 0.1073
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Brugia malayi CHE-14 protein 0.0045 0.0243 0.1082
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0637 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Loa Loa (eye worm) hypothetical protein 0.0061 0.0357 0.1589
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.006 0.006
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0095 0.0601 0.5321
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0162 0.072
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0013 0.0017 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Echinococcus multilocularis dna polymerase kappa 0.002 0.0069 0.0069
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Plasmodium falciparum proline--tRNA ligase 0.0113 0.0736 0.075
Schistosoma mansoni hypothetical protein 0.0043 0.0232 0.0232
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0243 0.1082
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Schistosoma mansoni DNA polymerase eta 0.002 0.0069 0.0069
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0308
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0245 0.1106
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0113 0.0736 0.3322
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0245 0.1102
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0097 0.062 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0324 0.2247 0.2247
Trypanosoma cruzi subtilisin peptidase 0.0013 0.0017 0.0076
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0061 0.0363 0.3113
Echinococcus multilocularis solute carrier family 22 0.0046 0.0249 0.0249
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.006 0.0266
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0122 0.0551
Echinococcus multilocularis General substrate transporter 0.0279 0.192 0.192
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0249 0.111
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0018 0.0053 0.0797
Echinococcus granulosus solute carrier family 22 0.0046 0.0249 0.0249
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0122 0.1073
Brugia malayi hypothetical protein 0.0073 0.0446 0.1985
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0122 0.0547
Schistosoma mansoni glucose transport protein 0.0324 0.2247 0.2247
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0249 0.111
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0013 0.0017 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.006 0.0266
Schistosoma mansoni sugar transporter 0.0046 0.0249 0.0249
Schistosoma mansoni hypothetical protein 0.0043 0.0232 0.0232
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0122 0.1073
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0122 0.0543
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0001 0.0005
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0011 0.0001 0.0001
Chlamydia trachomatis lysine--tRNA ligase 0.0072 0.0441 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0122 0.0945
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Onchocerca volvulus Putative transporter 0.0046 0.0249 0.1905
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0113 0.0736 0.332
Loa Loa (eye worm) fli-1 protein 0.0215 0.1465 0.6521
Plasmodium falciparum mitogen-activated protein kinase 2 0.0524 0.3681 0.3759
Schistosoma mansoni hypothetical protein 0.0324 0.2247 0.2247
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0249 0.111
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0011 0.0001 0.0001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0069 0.0069
Trichomonas vaginalis sugar transporter, putative 0.0101 0.0643 0.2864
Leishmania major glucose transporter/membrane transporter D2, putative 0.0101 0.0643 0.2904
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0053 0.0466
Leishmania major hypothetical protein, conserved 0.0016 0.0038 0.0169
Giardia lamblia DINP protein human, muc B family 0.002 0.0069 0.1102
Plasmodium falciparum calcium-dependent protein kinase 5 0.01 0.0637 0.065
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Trypanosoma brucei small ubiquitin-related modifier 0.0032 0.0155 0.0698
Echinococcus multilocularis dna polymerase eta 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0045 0.0243 0.1082
Schistosoma mansoni hypothetical protein 0.0043 0.0232 0.0232
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0053 0.0241
Toxoplasma gondii sugar transporter ST3 0.0046 0.0249 0.0383
Entamoeba histolytica hypothetical protein 0.0073 0.0446 0.6661
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0122 0.0543
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0249 0.111
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.043 0.3801
Toxoplasma gondii subtilisin SUB2 0.0013 0.0017 0.0025
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0053 0.0238
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0045 0.0243 0.0243
Trypanosoma cruzi glucose transporter, putative 0.0046 0.0249 0.1127
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.111
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.01 0.0637 0.098
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0017 0.0075
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0637 0.0637
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.006 0.0267
Loa Loa (eye worm) sugar transporter 0.0324 0.2247 1
Mycobacterium ulcerans integral membrane transport protein 0.0046 0.0249 0.2203
Trypanosoma brucei unspecified product 0.0014 0.0024 0.0103
Toxoplasma gondii facilitative glucose transporter GT1 0.0324 0.2247 0.346
Echinococcus granulosus solute carrier family 22 0.0046 0.0249 0.0249
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0069
Trypanosoma brucei glucose transporter, putative 0.0101 0.0643 0.2904
Mycobacterium ulcerans sugar transporter 0.0046 0.0249 0.2203
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0053 0.0238
Mycobacterium ulcerans acyl-CoA synthetase 0.0095 0.0601 0.5321
Loa Loa (eye worm) SMO-1 protein 0.0032 0.0155 0.0691
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0001 0.0001

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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