Detailed information for compound 870045

Basic information

Technical information
  • TDR Targets ID: 870045
  • Name: 2-chloro-4-nitro-N-pyridin-4-ylbenzamide
  • MW: 277.663 | Formula: C12H8ClN3O3
  • H donors: 1 H acceptors: 4 LogP: 2.14 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc(cc1Cl)[N+](=O)[O-])Nc1ccncc1
  • InChi: 1S/C12H8ClN3O3/c13-11-7-9(16(18)19)1-2-10(11)12(17)15-8-3-5-14-6-4-8/h1-7H,(H,14,15,17)
  • InChiKey: AKIWNJPXDHCKDF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-chloro-4-nitro-N-(4-pyridyl)benzamide
  • 2-chloro-4-nitro-N-pyridin-4-yl-benzamide
  • Oprea1_724812
  • STK158537
  • EU-0033411
  • ZINC00225355

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis tubulin, putative 0.0022 0.0072 0.0212
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Loa Loa (eye worm) alpha-tubulin 0.0054 0.0398 0.038
Schistosoma mansoni NAD dehydrogenase 0.0083 0.0691 0.0673
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0061 0.0464 0.1371
Schistosoma mansoni smdr1 0.0019 0.0038 0.0019
Brugia malayi cDNA sequence BC016226 0.0083 0.0691 0.1997
Schistosoma mansoni multidrug resistance protein 0.0019 0.0038 0.0019
Leishmania major hypothetical protein, conserved 0.0023 0.008 0.0905
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0018 0.0031 0.0093
Onchocerca volvulus 0.0154 0.1421 0.8248
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trypanosoma cruzi histone deacetylase 1, putative 0.0041 0.0258 0.3562
Echinococcus granulosus tubulin gamma 1 chain 0.0039 0.0246 0.0675
Loa Loa (eye worm) acetyltransferase 0.0023 0.008 0.0061
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0061 0.0464 0.1371
Entamoeba histolytica hypothetical protein 0.0019 0.0038 0.0049
Echinococcus multilocularis bromodomain containing 2 0.0347 0.3384 0.3424
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0046 1
Echinococcus multilocularis tubulin beta 1 chain 0.0054 0.0393 0.0381
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0037 0.0224 0.0662
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.008 0.0905
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0061 0.0464 0.6479
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Loa Loa (eye worm) CBP-B 0.0023 0.008 0.0061
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0083 0.0691 1
Plasmodium vivax ABC transporter B family member 3, putative 0.0019 0.0038 0.0553
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0046 0.0673
Echinococcus multilocularis 0.0019 0.0038 0.002
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0038 0.002
Brugia malayi Thioredoxin reductase 0.0057 0.0428 0.1215
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0038 0.0269
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Leishmania major pentamidine resistance protein 1 0.0019 0.0038 0.0289
Schistosoma mansoni smdr2 0.0061 0.0464 0.0446
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0046 1
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0023 0.008 0.0181
Schistosoma mansoni transcription initiation factor tfiid 0.0023 0.008 0.0061
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0188 0.176 0.5174
Echinococcus multilocularis tubulin alpha 1C chain 0.0054 0.0398 0.0386
Entamoeba histolytica P-glycoprotein-2, putative 0.0061 0.0464 0.3112
Trypanosoma cruzi Bromodomain, putative 0.0023 0.008 0.0905
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0154 0.1421 0.42
Echinococcus multilocularis tubulin alpha chain 0.0054 0.0398 0.0386
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0038 0.0269
Entamoeba histolytica hypothetical protein 0.0023 0.008 0.0346
Schistosoma mansoni alpha tubulin 0.0054 0.0398 0.038
Echinococcus multilocularis Bromodomain containing protein 0.0154 0.1421 0.1427
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0061 0.0464 0.0507
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.0393 0.0381
Loa Loa (eye worm) tubulin alpha-2 chain 0.0054 0.0398 0.038
Trypanosoma brucei Bromodomain, putative 0.0023 0.008 0.0905
Brugia malayi Tubulin alpha chain 0.0054 0.0398 0.1128
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0061 0.0464 0.0446
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0428 0.041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.9846 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0021 0.006 0.0177
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0019
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.0083 0.0691 0.486
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0428 0.6083
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0083 0.0691 0.0684
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0019 0.0038 0.0289
Trypanosoma brucei tubulin gamma chain 0.0039 0.0246 0.3382
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0044 0.0025
Loa Loa (eye worm) tubulin beta-1 chain 0.0054 0.0393 0.0375
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0083 0.0691 1
Toxoplasma gondii exonuclease III APE 0.002 0.0044 0.031
Schistosoma mansoni alpha tubulin 0.0054 0.0398 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Schistosoma mansoni multidrug resistance protein 0.0061 0.0464 0.0446
Brugia malayi Bromodomain containing protein 0.0347 0.3384 1
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Schistosoma mansoni zinc finger protein 0.0023 0.008 0.0061
Echinococcus granulosus peregrin 0.0023 0.008 0.0181
Toxoplasma gondii histone deacetylase HDAC2 0.0041 0.0258 0.1816
Plasmodium vivax ABC transporter B family member 6, putative 0.0019 0.0038 0.0553
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0083 0.0691 1
Brugia malayi RE18450p 0.0083 0.0691 0.1997
Entamoeba histolytica tubulin alpha-1 chain 0.0054 0.0398 0.264
Giardia lamblia Hypothetical protein 0.0018 0.0031 0.009
Schistosoma mansoni hypothetical protein 0.0128 0.115 0.1133
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0083 0.0691 0.0673
Brugia malayi Tubulin gamma chain 0.0039 0.0246 0.0675
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.0061
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0347 0.3384 0.3372
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0398 0.1177
Loa Loa (eye worm) tubulin alpha chain 0.0054 0.0398 0.038
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.1323 0.1323
Brugia malayi BRM protein 0.0023 0.008 0.0181
Echinococcus granulosus geminin 0.0128 0.115 0.3362
Echinococcus multilocularis histone deacetylase 1 0.0041 0.0258 0.0244
Echinococcus granulosus tubulin alpha 1C chain 0.0054 0.0398 0.1128
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Plasmodium falciparum tubulin delta chain, putative 0.0017 0.0019 0.0272
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0042 0.0277 0.0818
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.0393 0.0381
Echinococcus granulosus tubulin alpha chain 0.0054 0.0398 0.1128
Trichomonas vaginalis histone deacetylase, putative 0.0041 0.0258 0.0763
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0038 0.002
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0021 0.006 0.0123
Trypanosoma cruzi beta tubulin, putative 0.0054 0.0393 0.5571
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0037 0.0224 0.0206
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.1175 0.1283
Echinococcus granulosus multidrug resistance protein 1 0.0042 0.0277 0.0767
Trichomonas vaginalis bromodomain-containing protein, putative 0.0347 0.3384 1
Echinococcus granulosus tubulin beta 4A class IVa 0.0054 0.0393 0.1113
Plasmodium vivax ABC transporter B family member 7, putative 0.0019 0.0038 0.0553
Echinococcus granulosus multidrug resistance protein 1 0.0061 0.0464 0.1323
Trichomonas vaginalis ABC transporter, putative 0.0061 0.0464 0.1371
Brugia malayi Tubulin alpha-2 chain 0.0054 0.0398 0.1128
Loa Loa (eye worm) glutathione reductase 0.0057 0.0428 0.041
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.0393 0.0381
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.1323 0.1446
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0019 0.0038 0.0038
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0083 0.0691 0.4744
Trichomonas vaginalis hypothetical protein 0.0023 0.008 0.0235
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0083 0.0691 0.0684
Loa Loa (eye worm) ABC transporter 0.0019 0.0038 0.0019
Toxoplasma gondii hypothetical protein 0.0023 0.008 0.056
Trichomonas vaginalis tubulin alpha chain, putative 0.0039 0.0246 0.0727
Loa Loa (eye worm) tubulin beta-4 chain 0.0054 0.0393 0.0375
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0038 0.0269
Brugia malayi ABC transporter family protein 0.0019 0.0038 0.0058
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0038 0.0269
Leishmania major hypothetical protein, conserved 0.0023 0.008 0.0905
Toxoplasma gondii bromodomain-containing protein 0.0023 0.008 0.056
Echinococcus granulosus Tubulin alpha 1 chain 0.0054 0.0398 0.1128
Echinococcus multilocularis tubulin subunit TubB 0.0054 0.0398 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trypanosoma brucei epsilon tubulin 0.0039 0.0246 0.3382
Leishmania major hypothetical protein, conserved 0.0083 0.0691 1
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.0061
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0023 0.008 0.0235
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Loa Loa (eye worm) hypothetical protein 0.0061 0.0464 0.0446
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Entamoeba histolytica bromodomain-containing protein 0.0023 0.008 0.0346
Plasmodium vivax ABC transporter B family member 4, putative 0.0019 0.0038 0.0553
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0019 0.0038 0.0289
Entamoeba histolytica tubulin family protein 0.0054 0.0393 0.2602
Schistosoma mansoni phd finger protein 0.0023 0.008 0.0061
Trypanosoma brucei alpha tubulin, putative 0.0022 0.0072 0.0787
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0039 0.0246 0.1731
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase GlpD2 0.0083 0.0691 0.0691
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0019 0.0038 0.0553
Loa Loa (eye worm) hypothetical protein 0.0041 0.0258 0.024
Brugia malayi acetyltransferase, GNAT family protein 0.0023 0.008 0.0181
Schistosoma mansoni fad oxidoreductase 0.0083 0.0691 0.0673
Echinococcus granulosus ATP binding cassette sub family B 0.0019 0.0038 0.0058
Echinococcus granulosus ATP binding cassette sub family B 0.0018 0.0031 0.0038
Loa Loa (eye worm) tubulin alpha 2 0.0037 0.0224 0.0206
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Onchocerca volvulus Putative fad oxidoreductase 0.0083 0.0691 0.3784
Echinococcus multilocularis multidrug resistance protein 1 0.0061 0.0464 0.0453
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0046 0.0673
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Echinococcus granulosus tubulin alpha 3 chain 0.0054 0.0398 0.1128
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0046 0.0412
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0019 0.0038 0.0553
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0023 0.008 0.0062
Echinococcus granulosus protein kinase C binding protein 1 0.0023 0.008 0.0181
Loa Loa (eye worm) beta-tubulin 0.0054 0.0393 0.0375
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0061 0.0464 0.3264
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Trypanosoma cruzi epsilon tubulin, putative 0.0039 0.0246 0.3382
Giardia lamblia Transcription regulatory protein SNF2 0.0023 0.008 0.0434
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Entamoeba histolytica P-glyco protein 6, putative 0.0061 0.0464 0.3112
Echinococcus granulosus histone acetyltransferase KAT2B 0.0023 0.008 0.0181
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0398 0.1177
Giardia lamblia Hypothetical protein 0.0023 0.008 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain containing protein, putative 0.0154 0.1421 0.42
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0019 0.0038 0.0289
Loa Loa (eye worm) hypothetical protein 0.0083 0.0691 0.0673
Brugia malayi multidrug resistance related protein 1 0.0019 0.0038 0.0058
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0023 0.008 0.0235
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0021 0.006 0.0614
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0019 0.0038 0.0042
Entamoeba histolytica P-glycoprotein-5 0.0061 0.0464 0.3112
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Echinococcus multilocularis tubulin alpha 3 chain 0.0054 0.0398 0.0386
Plasmodium falciparum ABC transporter B family member 7, putative 0.0019 0.0038 0.0553
Echinococcus granulosus beta tubulin 0.0054 0.0393 0.1113
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0046 0.0327
Entamoeba histolytica tubulin family protein 0.0054 0.0393 0.2602
Plasmodium falciparum thioredoxin reductase 0.0057 0.0428 0.6189
Echinococcus multilocularis tubulin alpha 3 chain 0.0054 0.0398 0.0386
Loa Loa (eye worm) hypothetical protein 0.006 0.0457 0.0439
Trichomonas vaginalis histone deacetylase, putative 0.0041 0.0258 0.0763
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0046 0.0327
Trypanosoma brucei beta tubulin 0.0054 0.0393 0.5571
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0019 0.0038 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Plasmodium falciparum glutathione reductase 0.0057 0.0428 0.6189
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Schistosoma mansoni tubulin subunit beta 0.0054 0.0393 0.0375
Trichomonas vaginalis tubulin epsilon chain, putative 0.0054 0.0393 0.1162
Echinococcus granulosus multidrug resistance protein 1 0.0042 0.0277 0.0767
Echinococcus granulosus histone deacetylase 3 0.0041 0.0258 0.0711
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Brugia malayi ATPase, AAA family protein 0.0023 0.008 0.0181
Brugia malayi histone deacetylase 3 (HD3) 0.0041 0.0258 0.0711
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0056
Brugia malayi ABC transporter 0.0018 0.0031 0.0038
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Brugia malayi TAZ zinc finger family protein 0.0023 0.008 0.0181
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0023 0.008 0.0062
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0018 0.0031 0.0093
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis tubulin alpha chain, putative 0.0054 0.0393 0.1162
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0023 0.008 0.0905
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0023 0.008 0.0235
Echinococcus granulosus ATP binding cassette sub family B 0.0019 0.0038 0.0058
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0061 0.0464 0.0453
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0019 0.0038 0.0113
Entamoeba histolytica P-glycoprotein 5, putative 0.0061 0.0464 0.3112
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0019 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0061 0.0464 0.0453
Entamoeba histolytica tubulin gamma chain 0.0039 0.0246 0.1544
Trichomonas vaginalis tubulin epsilon chain, putative 0.0017 0.0019 0.0056
Schistosoma mansoni multidrug resistance protein 0.0061 0.0464 0.0446
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0046 0.0412
Trichomonas vaginalis tubulin epsilon chain, putative 0.0054 0.0398 0.1177
Trypanosoma brucei beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0154 0.1421 0.42
Leishmania major p-glycoprotein 0.0061 0.0464 0.6624
Schistosoma mansoni histone deacetylase 0.0041 0.0258 0.024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Entamoeba histolytica ABC transporter, putative 0.0019 0.0038 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0044 0.013
Trichomonas vaginalis ABC transporter, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0021 0.006 0.0177
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0019 0.0038 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0046 0.0412
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0023 0.008 0.056
Trypanosoma cruzi histone deacetylase 1, putative 0.0041 0.0258 0.3562
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0083 0.0691 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0054 0.0398 0.1128
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Schistosoma mansoni tubulin subunit gamma 0.0039 0.0246 0.0228
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0019 0.0038 0.0042
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.0393 0.1113
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0056
Toxoplasma gondii beta tubulin 0.0054 0.0393 0.2766
Toxoplasma gondii histone lysine methyltransferase SET1 0.0023 0.008 0.056
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0046 0.0412
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Echinococcus multilocularis 0.0023 0.008 0.0062
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0046 0.0412
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0044 0.018
Trichomonas vaginalis bromodomain containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0023 0.008 0.0062
Trypanosoma cruzi Bromodomain, putative 0.0023 0.008 0.0905
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0046 0.0412
Onchocerca volvulus 0.0023 0.008 0.0049
Brugia malayi hypothetical protein 0.0182 0.1708 0.502
Loa Loa (eye worm) alpha-tubulin 0.0054 0.0398 0.038
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Echinococcus multilocularis peregrin 0.0023 0.008 0.0062
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Plasmodium vivax multidrug resistance protein 1, putative 0.0061 0.0464 0.6716
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Onchocerca volvulus 0.0023 0.008 0.0049
Trichomonas vaginalis abcb9, putative 0.0061 0.0464 0.1371
Schistosoma mansoni multidrug resistance protein 0.0061 0.0464 0.0446
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0019 0.0038 0.0289
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.0393 0.1113
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.0061
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0061 0.0464 0.6624
Echinococcus granulosus bromodomain containing 2 0.0347 0.3384 1
Brugia malayi Muscleblind-like protein 0.018 0.1687 0.4957
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0021 0.006 0.0041
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0023 0.008 0.0235
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0023 0.008 0.0905
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0023 0.008 0.1152
Toxoplasma gondii ABC transporter family protein 0.0019 0.0038 0.0269
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0046 0.0046
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Schistosoma mansoni multidrug resistance protein 0.0019 0.0038 0.0019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Schistosoma mansoni helicase 0.0023 0.008 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Trichomonas vaginalis tubulin, putative 0.0022 0.0072 0.0212
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0023 0.008 0.0181
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0019 0.0038 0.7023
Trichomonas vaginalis taga, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis histone deacetylase, putative 0.0041 0.0258 0.0763
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0236 0.0221
Plasmodium falciparum tubulin gamma chain 0.0039 0.0246 0.3562
Giardia lamblia Multidrug resistance-associated protein 1 0.0019 0.0038 0.0139
Loa Loa (eye worm) hypothetical protein 0.0061 0.0464 0.0446
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0083 0.0691 0.3784
Plasmodium falciparum glutathione reductase 0.002 0.0046 0.0673
Brugia malayi P-glycoprotein-like protein 0.0019 0.0038 0.0058
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0018 0.0031 0.0093
Trypanosoma brucei p-glycoprotein 0.0019 0.0038 0.0289
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0019 0.0038 0.0058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0044 0.0376
Echinococcus multilocularis peroxisome assembly protein 26 0.0054 0.0398 0.0386
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0044 0.0075
Brugia malayi beta-tubulin, identical 0.0054 0.0393 0.1113
Leishmania major ABC-thiol transporter 0.0019 0.0038 0.0289
Toxoplasma gondii alpha tubulin TUBA1 0.0054 0.0398 0.2803
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0272 0.0254
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Echinococcus granulosus bromodomain containing protein 8 0.0023 0.008 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Plasmodium falciparum histone deacetylase 1 0.0041 0.0258 0.3737
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0061 0.0464 0.1323
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.1323 0.1446
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0061 0.0464 0.1323
Loa Loa (eye worm) BEN-1 protein 0.0054 0.0393 0.0375
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0044 0.013
Plasmodium vivax tubulin alpha chain, putative 0.0054 0.0398 0.5766
Giardia lamblia Histone deacetylase 0.0041 0.0258 0.1707
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0046 0.0197
Echinococcus multilocularis geminin 0.0128 0.115 0.1151
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0083 0.0691 0.1997
Echinococcus multilocularis CREB binding protein 0.0023 0.008 0.0062
Trichomonas vaginalis lymphoid specific helicase, putative 0.0023 0.008 0.0235
Chlamydia trachomatis D-amino acid dehydrogenase 0.0083 0.0691 1
Mycobacterium ulcerans thiamine biosynthesis oxidoreductase ThiO 0.0083 0.0691 0.0691
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Loa Loa (eye worm) bromodomain containing protein 0.0154 0.1421 0.1405
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Trypanosoma brucei multidrug resistance protein E 0.0019 0.0038 0.0289
Echinococcus multilocularis tubulin epsilon chain 0.0039 0.0246 0.0231
Trypanosoma brucei beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0018 0.0031 0.009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Plasmodium falciparum alpha tubulin 2 0.0054 0.0398 0.5766
Brugia malayi ABC transporter transmembrane region family protein 0.0019 0.0038 0.0058
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0023 0.008 0.0049
Echinococcus multilocularis bromodomain containing protein 8 0.0023 0.008 0.0062
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase 0.0083 0.0691 0.0691
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0019 0.0038 0.0289
Brugia malayi hypothetical protein 0.0019 0.0038 0.0058
Brugia malayi multidrug resistance protein 3 0.0061 0.0464 0.1323
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0019
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Schistosoma mansoni ap endonuclease 0.002 0.0044 0.0025
Schistosoma mansoni bromodomain containing protein 0.0023 0.008 0.0061
Trypanosoma cruzi Bromodomain, putative 0.0023 0.008 0.0905
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Trichomonas vaginalis tubulin alpha chain, putative 0.0022 0.0072 0.0212
Schistosoma mansoni bromodomain containing 0.0023 0.008 0.0061
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0019 0.0038 0.0289
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Loa Loa (eye worm) hypothetical protein 0.0083 0.0691 0.0673
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0188 0.176 0.5174
Trypanosoma brucei Bromodomain factor 1 0.0023 0.008 0.0905
Entamoeba histolytica P-glycoprotein 6, putative 0.0019 0.0038 0.0049
Trypanosoma brucei epsilon tubulin 0.0039 0.0246 0.3382
Echinococcus multilocularis hypothetical protein 0.0054 0.0398 0.0386
Brugia malayi bromodomain containing protein 0.0023 0.008 0.0181
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0428 0.0467
Toxoplasma gondii alpha-tubulin I, putative 0.0054 0.0398 0.2803
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0019 0.0038 0.0038
Plasmodium vivax glutathione reductase, putative 0.0057 0.0428 0.6189
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Schistosoma mansoni tubulin subunit epsilon 0.0039 0.0246 0.0228
Echinococcus multilocularis tubulin alpha 1C chain 0.0054 0.0398 0.0386
Plasmodium falciparum bromodomain protein 1 0.0023 0.008 0.1152
Mycobacterium leprae Possible thiamine biosynthesis oxidoreductase ThiO 0.0083 0.0691 0.0691
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0083 0.0691 1
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Giardia lamblia Kinase, putative 0.0154 0.1421 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Toxoplasma gondii hypothetical protein 0.0083 0.0691 0.486
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0061 0.0464 0.3264
Schistosoma mansoni tubulin subunit beta 0.0054 0.0393 0.0375
Echinococcus multilocularis Tubulin alpha 1 chain 0.0054 0.0398 0.0386
Giardia lamblia Beta tubulin 0.0054 0.0393 0.2669
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0044 0.912
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.0393 0.1113
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0017 0.0019 0.0056
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0083 0.0691 0.1997
Leishmania major trypanothione reductase 0.0057 0.0428 0.6083
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.1175 0.1283
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0023 0.008 0.0905
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Echinococcus multilocularis muscleblind protein 0.018 0.1687 0.1697
Echinococcus multilocularis histone deacetylase 3 0.0041 0.0258 0.0244
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0044 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0044 0.0376
Brugia malayi hypothetical protein 0.0131 0.1186 0.3469
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0061 0.0464 0.1371
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Schistosoma mansoni fad oxidoreductase 0.0083 0.0691 0.0673
Onchocerca volvulus 0.0182 0.1708 1
Loa Loa (eye worm) hypothetical protein 0.0347 0.3384 0.3372
Plasmodium vivax bromodomain protein, putative 0.0023 0.008 0.1152
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0019 0.0038 0.0289
Giardia lamblia MRP-like ABC transporter 0.0019 0.0038 0.0139
Schistosoma mansoni tubulin subunit alpha 0.0054 0.0398 0.038
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0023 0.008 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trypanosoma brucei alpha tubulin 0.0054 0.0398 0.5648
Trichomonas vaginalis histone deacetylase, putative 0.0041 0.0258 0.0763
Echinococcus multilocularis Bromodomain containing protein 0.0023 0.008 0.0062
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0038 0.0269
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0021 0.006 0.0042
Toxoplasma gondii thioredoxin reductase 0.0057 0.0428 0.3008
Trichomonas vaginalis tubulin, putative 0.0017 0.0019 0.0056
Plasmodium vivax ABC transporter B family member 5, putative 0.0019 0.0038 0.0553
Trichomonas vaginalis histone deacetylase, putative 0.0041 0.0258 0.0763
Mycobacterium ulcerans cell division protein FtsZ 0.0017 0.0019 0.0019
Echinococcus granulosus tubulin alpha chain 0.0054 0.0398 0.1128
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0041 0.0258 0.0763
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Echinococcus multilocularis tubulin subunit beta 0.0054 0.0393 0.0381
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0083 0.0691 0.1997
Entamoeba histolytica tubulin alpha chain, putative 0.0054 0.0398 0.264
Plasmodium vivax tubulin epsilon chain, putative 0.0039 0.0246 0.3562
Trypanosoma brucei alpha tubulin 0.0054 0.0398 0.5648
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.1175 0.1283
Trichomonas vaginalis tubulin epsilon chain, putative 0.0054 0.0393 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0046 0.0082
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0046 0.0137
Plasmodium vivax tubulin beta chain, putative 0.0054 0.0393 0.5691
Loa Loa (eye worm) histone deacetylase 1 0.0041 0.0258 0.024
Echinococcus granulosus muscleblind protein 0.018 0.1687 0.4957
Echinococcus granulosus zinc finger protein 0.0023 0.008 0.0181
Loa Loa (eye worm) hypothetical protein 0.0083 0.0691 0.0673
Trichomonas vaginalis tubulin alpha chain, putative 0.0022 0.0072 0.0212
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0023 0.008 0.1152
Plasmodium falciparum multidrug resistance-associated protein 1 0.0019 0.0038 0.0553
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0054 0.0398 0.1177
Giardia lamblia Beta tubulin 0.0054 0.0393 0.2669
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0083 0.0691 0.1997
Plasmodium falciparum ABC transporter B family member 5, putative 0.0019 0.0038 0.0553
Echinococcus multilocularis tubulin alpha chain 0.0054 0.0398 0.0386
Schistosoma mansoni tubulin subunit beta 0.0054 0.0393 0.0375
Echinococcus granulosus beta tubulin 0.0054 0.0393 0.1113
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0061 0.0464 0.0453
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0019 0.0038 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0031 0.0093
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.1175 0.1175
Echinococcus granulosus tubulin subunit TubB 0.0054 0.0398 0.1128
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0188 0.176 0.1772
Trypanosoma cruzi alpha tubulin, putative 0.0054 0.0398 0.5648
Trichomonas vaginalis tubulin epsilon chain, putative 0.0054 0.0398 0.1177
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Echinococcus multilocularis Tubulin alpha 1 chain 0.0054 0.0398 0.0386
Leishmania major gamma-tubulin 0.0039 0.0246 0.3382
Schistosoma mansoni polybromo-1 0.0023 0.008 0.0061
Echinococcus multilocularis multidrug resistance protein 1 0.0061 0.0464 0.0453
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0021 0.006 0.0614
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.0393 0.0381
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0023 0.008 0.0235
Onchocerca volvulus 0.0061 0.0464 0.2397
Plasmodium falciparum ABC transporter B family member 4, putative 0.0019 0.0038 0.0553
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0083 0.0691 1
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0083 0.0691 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0038 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0046 0.0412
Brugia malayi alpha-tubulin 0.0054 0.0398 0.1128
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0236 0.0645
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Trichomonas vaginalis bromodomain-containing protein, putative 0.0215 0.2042 0.6035
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0428 0.1215
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0061 0.0464 0.0453
Schistosoma mansoni tubulin subunit beta 0.0054 0.0393 0.0375
Schistosoma mansoni bromodomain containing protein 0.0023 0.008 0.0061
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0083 0.0691 1
Plasmodium vivax tubulin gamma chain, putative 0.0039 0.0246 0.3562
Echinococcus multilocularis tubulin alpha chain 0.0054 0.0398 0.0386
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0083 0.0691 1
Loa Loa (eye worm) BEN-1 protein 0.0054 0.0393 0.0375
Entamoeba histolytica bromodomain-containing protein 0.0154 0.1421 1
Echinococcus granulosus CREB binding protein 0.0023 0.008 0.0181
Echinococcus granulosus multidrug resistance associated protein 7 0.0019 0.0038 0.0058
Echinococcus multilocularis protein kinase C binding protein 1 0.0023 0.008 0.0062
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0054 0.0393 0.0381
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Brugia malayi ABC transporter transmembrane region family protein 0.0018 0.0031 0.0038
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0398 0.1177
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0021 0.006 0.0041
Mycobacterium tuberculosis Probable reductase 0.013 0.1175 0.1283
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Brugia malayi Tubulin beta-1 chain 0.0054 0.0393 0.1113
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0041 0.0258 0.0763
Trichomonas vaginalis bromodomain-containing protein, putative 0.0215 0.2042 0.6035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Giardia lamblia Multidrug resistance-associated protein 1 0.0018 0.0031 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0017 0.0019 0.0132
Echinococcus granulosus tubulin subunit beta 0.0054 0.0393 0.1113
Trichomonas vaginalis bromodomain containing protein, putative 0.0023 0.008 0.0235
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0019 0.0038 0.0289
Echinococcus granulosus histone deacetylase 1 0.0041 0.0258 0.0711
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0032 0.0171 0.0506
Trichomonas vaginalis abcb9, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0038 0.0269
Echinococcus multilocularis muscleblind protein 1 0.018 0.1687 0.1697
Trypanosoma cruzi tubulin gamma chain 0.0039 0.0246 0.3382
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0018 0.0031 0.0013
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0044 0.0376
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0023 0.008 0.1152
Trypanosoma cruzi epsilon tubulin, putative 0.0039 0.0246 0.3382
Schistosoma mansoni tubulin subunit alpha 0.0054 0.0398 0.038
Echinococcus granulosus tubulin alpha chain 0.0054 0.0398 0.1128
Trichomonas vaginalis bromodomain containing protein, putative 0.0023 0.008 0.0235
Toxoplasma gondii beta-1 tubulin, putative 0.0054 0.0393 0.2766
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0061 0.0464 0.0453
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0023 0.008 0.0235
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0398 0.1177
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0019 0.0038 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Brugia malayi ABC transporter transmembrane region family protein 0.0019 0.0038 0.0058
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0236 0.0218
Plasmodium vivax delta tubulin, putative 0.0017 0.0019 0.0272
Entamoeba histolytica ATP-binding cassette protein, putative 0.0019 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0037 0.0224 0.0206
Toxoplasma gondii beta-tubulin, putative 0.0054 0.0393 0.2766
Loa Loa (eye worm) tubulin beta chain 0.0054 0.0393 0.0375
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Trypanosoma brucei alpha tubulin 0.0054 0.0398 0.5648
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.006 0.0457 0.1303
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Toxoplasma gondii bromodomain-containing protein 0.0023 0.008 0.056
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0022 0.0072 0.0212
Giardia lamblia Alpha-tubulin 0.0054 0.0398 0.2706
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0038 0.002
Giardia lamblia Alpha-tubulin 0.0054 0.0398 0.2706
Loa Loa (eye worm) hypothetical protein 0.0182 0.1708 0.1693
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0088 0.0745 0.5174
Schistosoma mansoni ap endonuclease 0.002 0.0044 0.0025
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Entamoeba histolytica bromodomain-containing protein 0.0154 0.1421 1
Echinococcus granulosus alpha tubulin 0.0054 0.0398 0.1128
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0061 0.0464 0.1371
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Echinococcus multilocularis ATP binding cassette sub family B 0.006 0.0457 0.0446
Giardia lamblia Hypothetical protein 0.0023 0.008 0.0434
Echinococcus granulosus global transcription activator snf2l2 0.0023 0.008 0.0181
Brugia malayi tubulin alpha chain - mouse 0.0054 0.0398 0.1128
Brugia malayi ABC transporter family protein 0.0061 0.0464 0.1323
Trichomonas vaginalis ABC transporter, putative 0.0061 0.0464 0.1371
Loa Loa (eye worm) hypothetical protein 0.0166 0.1544 0.1528
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0021 0.006 0.0614
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0019 0.0038 0.0289
Echinococcus granulosus Bromodomain containing protein 0.0023 0.008 0.0181
Trichomonas vaginalis tubulin gamma chain, putative 0.0039 0.0246 0.0727
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0236 0.0645
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.0061
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0044 0.0638
Entamoeba histolytica histone deacetylase, putative 0.0041 0.0258 0.1631
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0041 0.0258 0.0763
Toxoplasma gondii histone deacetylase HDAC3 0.0041 0.0258 0.1816
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0272 0.0254
Entamoeba histolytica P-glycoprotein 6, putative 0.0019 0.0038 0.0049
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Echinococcus granulosus PH interacting protein 0.0023 0.008 0.0181
Brugia malayi Tubulin beta chain 0.0022 0.0072 0.0157
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0023 0.008 0.0061
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0398 0.1177
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0013
Brugia malayi tubulin alpha-2 chain 0.0054 0.0398 0.1128
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.1323 0.1446
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trypanosoma brucei trypanothione reductase 0.0057 0.0428 0.6083
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0019 0.0038 0.0289
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0083 0.0691 0.0673
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.021 0.0621
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0044 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.1807 0.534
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Loa Loa (eye worm) tubulin alpha chain 0.0054 0.0398 0.038
Trypanosoma brucei Bromodomain, putative 0.0023 0.008 0.0905
Trypanosoma brucei epsilon tubulin 0.0039 0.0246 0.3382
Echinococcus multilocularis multidrug resistance protein 1 0.0042 0.0277 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0013
Entamoeba histolytica P-glycoprotein-2 0.0061 0.0464 0.3112
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0083 0.0691 1
Trichomonas vaginalis conserved hypothetical protein 0.0215 0.2042 0.6035
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Plasmodium falciparum tubulin epsilon chain, putative 0.0039 0.0246 0.3562
Echinococcus multilocularis tubulin alpha 0.0039 0.0246 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Echinococcus granulosus peroxisome assembly protein 26 0.0054 0.0398 0.1128
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0428 0.0416
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.1175 0.1283
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.1175 0.1283
Mycobacterium leprae Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase) 0.0083 0.0691 0.0691
Echinococcus multilocularis polybromo 1 0.0023 0.008 0.0062
Schistosoma mansoni multidrug resistance protein 0.0019 0.0038 0.0019
Entamoeba histolytica ATP-binding cassette protein, putative 0.0019 0.0038 0.0049
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.0994 1 1
Plasmodium falciparum bromodomain protein 2, putative 0.0023 0.008 0.1152
Plasmodium vivax multidrug resistance protein 2, putative 0.0019 0.0038 0.0553
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0023 0.008 0.0181
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Echinococcus granulosus tubulin beta 1 chain 0.0054 0.0393 0.1113
Trypanosoma brucei Bromodomain, putative 0.0023 0.008 0.0905
Loa Loa (eye worm) hypothetical protein 0.018 0.1687 0.1671
Trichomonas vaginalis tubulin gamma chain, putative 0.0054 0.0393 0.1162
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0019 0.0038 0.0269
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0046 0.0673
Echinococcus granulosus polybromo 1 0.0023 0.008 0.0181
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0044 0.0026
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0044 0.912
Schistosoma mansoni alpha tubulin 0.0054 0.0398 0.038
Echinococcus multilocularis PH interacting protein 0.0023 0.008 0.0062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis tubulin, putative 0.0054 0.0393 0.1162
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0044 0.0048
Brugia malayi ABC transporter family protein 0.0019 0.0038 0.0058
Plasmodium falciparum thioredoxin reductase 0.002 0.0046 0.0673
Brugia malayi glutathione reductase 0.0057 0.0428 0.1215
Entamoeba histolytica multidrug resistance protein, putative 0.0019 0.0038 0.0049
Loa Loa (eye worm) tubulin alpha 2 0.0037 0.0224 0.0206
Entamoeba histolytica bromodomain-containing protein 0.0023 0.008 0.0346
Echinococcus granulosus tubulin alpha chain 0.0054 0.0398 0.1128
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Loa Loa (eye worm) ABC transporter 0.0019 0.0038 0.0019
Echinococcus granulosus tubulin alpha 1C chain 0.0054 0.0398 0.1128
Entamoeba histolytica P-glycoprotein-2 0.0061 0.0464 0.3112
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0019 0.0038 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Trypanosoma cruzi Bromodomain, putative 0.0023 0.008 0.0905
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Trichomonas vaginalis tubulin gamma chain, putative 0.0039 0.0246 0.0727
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0021 0.006 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trypanosoma cruzi Bromodomain, putative 0.0023 0.008 0.0905
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0023 0.008 0.0235
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Echinococcus multilocularis tubulin alpha chain 0.0054 0.0398 0.0386
Leishmania major histone deacetylase, putative 0.0041 0.0258 0.3562
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0083 0.0691 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0046 0.0046
Echinococcus granulosus tubulin alpha 0.0039 0.0246 0.0675
Loa Loa (eye worm) BRM protein 0.0023 0.008 0.0061
Entamoeba histolytica bromodomain-containing protein 0.0023 0.008 0.0346
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0044 0.009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0072 0.0212
Plasmodium falciparum tubulin beta chain 0.0054 0.0393 0.5691
Echinococcus multilocularis zinc finger protein 0.0023 0.008 0.0062
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0021 0.006 0.0614
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0044 0.0638
Plasmodium vivax bromodomain protein, putative 0.0023 0.008 0.1152
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.008 0.0061
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Entamoeba histolytica ankyrin repeat protein, putative 0.0023 0.008 0.0346
Loa Loa (eye worm) tubulin beta-2A chain 0.0054 0.0393 0.0375
Entamoeba histolytica ATP-binding cassette protein, putative 0.0019 0.0038 0.0049
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Trypanosoma cruzi multidrug resistance protein E, putative 0.0019 0.0038 0.0289
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0023 0.008 0.0235
Schistosoma mansoni tubulin subunit beta 0.0054 0.0393 0.0375
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0046 0.0137
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0046 0.0412
Trichomonas vaginalis bromodomain containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis abcb9, putative 0.0061 0.0464 0.1371
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0019 0.0038 0.0038
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0083 0.0691 0.3784
Loa Loa (eye worm) hypothetical protein 0.0021 0.006 0.0041
Trypanosoma brucei histone deacetylase 1 0.0041 0.0258 0.3562
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.021 0.0621
Echinococcus granulosus Tubulin alpha 1 chain 0.0054 0.0398 0.1128
Schistosoma mansoni tubulin subunit beta 0.0054 0.0393 0.0375
Schistosoma mansoni d-amino acid oxidase 0.0994 1 1
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0046 0.0082
Trypanosoma brucei beta tubulin 0.0039 0.0246 0.3382
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0046 0.0673
Brugia malayi Bromodomain containing protein 0.0347 0.3384 1
Schistosoma mansoni tubulin subunit alpha 0.0054 0.0398 0.038
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.0393 0.1113
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0019 0.0038 0.0019
Trichomonas vaginalis histone deacetylase, putative 0.0041 0.0258 0.0763
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Brugia malayi Tubulin alpha-2 chain 0.0054 0.0398 0.1128
Brugia malayi Histone deacetylase 1 0.0041 0.0258 0.0711
Plasmodium vivax tubulin alpha chain, putative 0.0054 0.0398 0.5766
Echinococcus granulosus multidrug resistance protein 1 0.0061 0.0464 0.1323
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0428 0.6189
Plasmodium falciparum bromodomain protein, putative 0.0023 0.008 0.1152
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0017 0.0019 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Schistosoma mansoni bromodomain containing protein 0.0023 0.008 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Trichomonas vaginalis ABC transporter, putative 0.0061 0.0464 0.1371
Entamoeba histolytica bromodomain-containing protein 0.0154 0.1421 1
Echinococcus multilocularis beta tubulin 0.0054 0.0393 0.0381
Toxoplasma gondii ABC transporter, putative 0.0019 0.0038 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Giardia lamblia Multidrug resistance-associated protein 1 0.0019 0.0038 0.0139
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Mycobacterium tuberculosis Possible thiamine biosynthesis oxidoreductase ThiO 0.0083 0.0691 0.0755
Plasmodium falciparum multidrug resistance protein 1 0.0061 0.0464 0.6716
Entamoeba histolytica P-glycoprotein-1 0.0061 0.0464 0.3112
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Toxoplasma gondii bromodomain-containing protein 0.0154 0.1421 1
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0083 0.0691 0.0691
Trichomonas vaginalis bromodomain containing protein, putative 0.0215 0.2042 0.6035
Leishmania major p-glycoprotein e 0.0019 0.0038 0.0289
Leishmania major epsilon tubulin, putative 0.0039 0.0246 0.3382
Loa Loa (eye worm) multidrug resistance protein 3 0.0061 0.0464 0.0446
Trichomonas vaginalis bromodomain-containing protein, putative 0.0347 0.3384 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Schistosoma mansoni histone deacetylase 0.0041 0.0258 0.024
Leishmania major histone deacetylase, putative 0.0041 0.0258 0.3562
Onchocerca volvulus Brd8 homolog 0.0023 0.008 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.1421 0.42
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0083 0.0691 0.0673
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0994 1 1
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0021 0.006 0.0123
Giardia lamblia Gamma tubulin 0.0039 0.0246 0.1621
Loa Loa (eye worm) hypothetical protein 0.0054 0.0398 0.038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Plasmodium falciparum ABC transporter B family member 3, putative 0.0019 0.0038 0.0553
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0083 0.0691 1
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0023 0.008 0.056
Loa Loa (eye worm) tubulin gamma chain 0.0039 0.0246 0.0228
Brugia malayi polybromodomain protein 0.0023 0.008 0.0181
Echinococcus multilocularis tubulin gamma 1 chain 0.0039 0.0246 0.0231
Schistosoma mansoni multidrug resistance protein 0.0019 0.0038 0.0019
Giardia lamblia Beta tubulin 0.0054 0.0393 0.2669
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0046 0.0412
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0083 0.0691 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0019 0.0038 0.0049
Brugia malayi ABC transporter family protein 0.0019 0.0038 0.0058
Echinococcus granulosus CREB binding protein 0.0023 0.008 0.0181
Echinococcus granulosus tubulin alpha 3 chain 0.0054 0.0398 0.1128
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.0083 0.0691 1
Brugia malayi ABC transporter 0.0019 0.0038 0.0058
Trypanosoma brucei AAA ATPase, putative 0.0023 0.008 0.0905
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.0393 0.0381
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Leishmania major hypothetical protein, conserved 0.0083 0.0691 1
Treponema pallidum NADH oxidase 0.002 0.0046 1
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.0911 0.9153 1
Mycobacterium leprae cell division protein FtsZ 0.0017 0.0019 0.0019
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0023 0.008 0.056
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0046 0.0412
Echinococcus granulosus tubulin epsilon chain 0.0039 0.0246 0.0675
Loa Loa (eye worm) tubulin alpha-3 chain 0.0032 0.0171 0.0153
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0046 0.0028
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0398 0.1177
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.006 0.0177
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0061 0.0464 0.1323
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Echinococcus granulosus Bromodomain containing protein 0.0023 0.008 0.0181
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.0393 0.1113
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0061 0.0464 0.1371
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0019
Trypanosoma cruzi bromodomain factor 2 protein 0.0023 0.008 0.0905
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Echinococcus granulosus tubulin alpha chain 0.0054 0.0398 0.1128
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0019 0.0038 0.0289
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis tubulin alpha chain, putative 0.0022 0.0072 0.0212
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0044 0.0376
Loa Loa (eye worm) ABC transporter 0.0019 0.0038 0.0019
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Schistosoma mansoni multidrug resistance protein 0.0019 0.0038 0.0019
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0046 0.0051
Loa Loa (eye worm) histone deacetylase 3 0.0041 0.0258 0.024
Trypanosoma cruzi bromodomain-containing protein 3 0.0023 0.008 0.0905
Echinococcus multilocularis beta tubulin 0.0054 0.0393 0.0381
Trypanosoma brucei beta tubulin 0.0054 0.0393 0.5571
Plasmodium vivax bromodomain protein, putative 0.0023 0.008 0.1152
Echinococcus multilocularis Tubulin alpha 1 chain 0.0054 0.0398 0.0386
Loa Loa (eye worm) hypothetical protein 0.018 0.1687 0.1671
Toxoplasma gondii bromodomain-containing protein 0.0023 0.008 0.056
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Schistosoma mansoni hypothetical protein 0.0128 0.115 0.1133
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Plasmodium falciparum multidrug resistance protein 2 0.0019 0.0038 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235
Plasmodium falciparum ABC transporter B family member 6, putative 0.0019 0.0038 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.006 0.0177
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0023 0.008 0.0061
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trypanosoma brucei alpha tubulin 0.0054 0.0398 0.5648
Schistosoma mansoni multidrug resistance protein 0.0018 0.0031 0.0013
Plasmodium vivax SET domain containing protein 0.0023 0.008 0.1152
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0061
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0019 0.0038 0.7023
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.0393 0.1162
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0061 0.0464 0.1371
Trichomonas vaginalis bromodomain-containing protein, putative 0.0154 0.1421 0.42
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0019 0.0038 0.0289
Plasmodium vivax histone deacetylase 1, putative 0.0041 0.0258 0.3737
Trypanosoma cruzi Bromodomain factor 1 0.0023 0.008 0.0905
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Plasmodium falciparum multidrug resistance-associated protein 2 0.0019 0.0038 0.0553
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0083 0.0691 1
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0088 0.0745 0.513
Leishmania major alpha tubulin 0.0054 0.0398 0.5648
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0061 0.0464 0.1323
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0166
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0019 0.0038 0.0289
Trichomonas vaginalis bromodomain-containing protein, putative 0.0215 0.2042 0.6035
Brugia malayi histone deacetylase 1 (HD1) 0.0041 0.0258 0.0711
Trichomonas vaginalis tubulin gamma chain, putative 0.0017 0.0019 0.0056
Brugia malayi Bromodomain containing protein 0.0023 0.008 0.0181
Schistosoma mansoni CREB-binding protein 2 0.0023 0.008 0.0061
Loa Loa (eye worm) hypothetical protein 0.0032 0.0171 0.0153
Echinococcus multilocularis global transcription activator snf2l2 0.0023 0.008 0.0062
Mycobacterium tuberculosis Cell division protein FtsZ 0.0017 0.0019 0.0021
Leishmania major beta tubulin 0.0054 0.0393 0.5571
Echinococcus multilocularis multidrug resistance associated protein 7 0.0019 0.0038 0.002
Echinococcus granulosus multidrug resistance associated protein 1 0.0019 0.0038 0.0058
Echinococcus multilocularis tubulin alpha chain 0.0054 0.0398 0.0386
Echinococcus granulosus multidrug resistance protein 1 0.0061 0.0464 0.1323
Echinococcus multilocularis multidrug resistance associated protein 1 0.0019 0.0038 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Plasmodium falciparum alpha tubulin 1 0.0054 0.0398 0.5766
Trichomonas vaginalis bromodomain-containing protein, putative 0.0023 0.008 0.0235
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0061 0.0464 0.1371
Giardia lamblia ABC transporter, putative 0.0019 0.0038 0.0139
Toxoplasma gondii bromodomain-containing protein 0.0023 0.008 0.056
Brugia malayi polybromodomain protein 0.0023 0.008 0.0181
Loa Loa (eye worm) hypothetical protein 0.0182 0.17 0.1684
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0019 0.0038 0.0289
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0046 0.0028
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.006 0.0177
Brugia malayi PHD-finger family protein 0.0023 0.008 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0235

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.122 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10.3183 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 14.1254 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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