Detailed information for compound 888055

Basic information

Technical information
  • TDR Targets ID: 888055
  • Name: 4-iodo-N-(2-phenylphenyl)benzenesulfonamide
  • MW: 435.279 | Formula: C18H14INO2S
  • H donors: 1 H acceptors: 2 LogP: 4.72 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Ic1ccc(cc1)S(=O)(=O)Nc1ccccc1c1ccccc1
  • InChi: 1S/C18H14INO2S/c19-15-10-12-16(13-11-15)23(21,22)20-18-9-5-4-8-17(18)14-6-2-1-3-7-14/h1-13,20H
  • InChiKey: LPGQJASYFHCMKH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii hypothetical protein 0.0054 0.0213 0.1962
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0535 0.2882 0.3385
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0019 0.0011
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0052 0.0338
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0174 0.0932
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0145
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.0019 0.0076
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0019 0.068
Schistosoma mansoni ran 0.0022 0.0033 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0077 0.0342 0.0431
Entamoeba histolytica hypothetical protein 0.0074 0.032 0.5697
Entamoeba histolytica hypothetical protein 0.0074 0.032 0.5697
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0123 0.0641
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.003 0.0079 0.0145
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.003 0.0079 0.0082
Echinococcus granulosus allatostatin A receptor 0.0535 0.2882 0.3385
Onchocerca volvulus 0.0077 0.0342 0.0431
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0395
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0535 0.2882 0.6043
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0099 0.019
Echinococcus granulosus neuropeptide Y receptor 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0123 0.0907
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0607 0.6697
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0535 0.2882 0.2876
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0371 0.0683
Echinococcus multilocularis neuropeptides capa receptor 0.0535 0.2882 0.2876
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0052 0.0338
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Loa Loa (eye worm) hypothetical protein 0.0076 0.0335 0.0685
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0548 0.304
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0174 0.0932
Echinococcus granulosus neuropeptide s receptor 0.0535 0.2882 0.3385
Schistosoma mansoni hypothetical protein 0.0535 0.2882 0.3385
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0535 0.2882 0.5199
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Brugia malayi jmjC domain containing protein 0.0058 0.0234 0.0489
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0123 0.0134
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0079 0.0145
Plasmodium vivax phosphodiesterase gamma, putative 0.003 0.0079 0.0673
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0083 0.0714
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.0545 0.3023
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.012 0.022
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0545 0.1002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Echinococcus multilocularis orexin receptor type 2 0.0535 0.2882 0.2876
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0108 0.0098
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0045 0.0082
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.075 0.1556
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0123 0.1967
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0548 0.6031
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0548 0.1133
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0052 0.0375
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0083 0.0375 0.0431
Echinococcus multilocularis lamin 0.0056 0.022 0.0211
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0083 0.0371 0.0427
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0125 0.2015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Echinococcus multilocularis somatostatin receptor 0.0535 0.2882 0.2876
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Leishmania major DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.005 0.0186 0.0177
Echinococcus granulosus somatostatin receptor 0.0535 0.2882 0.3385
Echinococcus granulosus serotonin receptor 0.0535 0.2882 0.3385
Loa Loa (eye worm) neuropeptide F receptor 0.0535 0.2882 0.6037
Toxoplasma gondii hypothetical protein 0.0019 0.0019 0.0091
Brugia malayi MAP kinase sur-1 0.0114 0.0545 0.1141
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0112 0.0531 0.1112
Leishmania major GTP-binding protein, putative 0.0022 0.0033 0.0132
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.012 0.0625
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0079 0.0395
Brugia malayi hypothetical protein 0.0043 0.0149 0.0309
Loa Loa (eye worm) beta-lactamase 0.0038 0.0123 0.0239
Onchocerca volvulus 0.0535 0.2882 0.5199
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0147
Echinococcus granulosus fmrfamide receptor 0.0535 0.2882 0.3385
Onchocerca volvulus 0.0535 0.2882 0.5199
Loa Loa (eye worm) intermediate filament protein 0.0056 0.022 0.0442
Echinococcus granulosus neuropeptide receptor A26 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Entamoeba histolytica transcription factor BTF3, putative 0.0038 0.012 0.191
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0535 0.2882 0.3385
Echinococcus multilocularis importin subunit beta 1 0.003 0.0076 0.0067
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0267 0.1456
Brugia malayi putative neuropeptide receptor 0.0535 0.2882 0.6043
Echinococcus multilocularis serotonin receptor 0.0535 0.2882 0.2876
Onchocerca volvulus 0.0038 0.0123 0.0021
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.022 0.0458
Plasmodium falciparum basic transcription factor 3b, putative 0.0038 0.012 0.7946
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0125 0.0608 0.5761
Schistosoma mansoni hypothetical protein 0.0074 0.032 0.0367
Echinococcus multilocularis muscleblind protein 1 0.0174 0.0878 0.087
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0123 0.1187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Echinococcus granulosus transcription factor btf3 0.0038 0.012 0.013
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0033 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0205 0.1048 0.1224
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0033 0.0132
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.003 0.0079 0.1147
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0052 0.0239
Brugia malayi Dopamine receptor protein 1 0.0535 0.2882 0.6043
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0123 0.0226
Schistosoma mansoni single-minded 0.0049 0.0182 0.0204
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0607 0.0704
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0395
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0052 0.0338
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0052 0.0375
Echinococcus multilocularis neuropeptides capa receptor 0.0535 0.2882 0.2876
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0116
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0019 0.001
Schistosoma mansoni hypothetical protein 0.0535 0.2882 0.3385
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0193 0.0982 0.0974
Brugia malayi jmjC domain containing protein 0.0058 0.0234 0.0489
Brugia malayi hypothetical protein 0.0043 0.0149 0.0309
Loa Loa (eye worm) hypothetical protein 0.0074 0.0323 0.066
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.015 0.1359
Loa Loa (eye worm) hypothetical protein 0.0077 0.0342 0.0699
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0234 0.0225
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0186 0.0373
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0083 0.0371 0.6697
Echinococcus granulosus g protein coupled receptor 0.0535 0.2882 0.3385
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Schistosoma mansoni ran 0.0022 0.0033 0.0028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0123 0.0239
Brugia malayi RNA, U transporter 1 0.0084 0.038 0.0794
Brugia malayi hypothetical protein 0.0164 0.082 0.1718
Echinococcus granulosus importin subunit beta 1 0.003 0.0076 0.0079
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0535 0.2882 0.2876
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0121 0.0582 0.0675
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.019 0.0968 0.096
Echinococcus multilocularis neuropeptide s receptor 0.0535 0.2882 0.2876
Schistosoma mansoni growth hormone secretagogue receptor 0.0535 0.2882 0.3385
Echinococcus granulosus survival motor neuron protein 1 0.0254 0.1322 0.1547
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Leishmania major mitochondrial DNA polymerase beta 0.0337 0.1782 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0052 0.0375
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Echinococcus multilocularis neuropeptide receptor 0.0535 0.2882 0.2876
Echinococcus multilocularis microtubule associated protein 2 0.1546 0.8497 0.8495
Schistosoma mansoni neuropeptide receptor 0.0535 0.2882 0.3385
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0123 0.1187
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Echinococcus multilocularis snurportin 1 0.0317 0.167 0.1662
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0076 0.0377
Onchocerca volvulus 0.0038 0.0123 0.0021
Onchocerca volvulus 0.0056 0.022 0.0202
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0079 0.0145
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0234 0.0265
Schistosoma mansoni hypothetical protein 0.0535 0.2882 0.3385
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0125 0.0608 0.0599
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0586 0.3163 0.6633
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0052 0.0338
Brugia malayi G protein-coupled receptor F59B2.13 0.0535 0.2882 0.6043
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0083 0.0714
Echinococcus granulosus g protein coupled receptor 0.0535 0.2882 0.3385
Onchocerca volvulus 0.0535 0.2882 0.5199
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0019 0.0037
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0114 0.0545 0.3023
Echinococcus multilocularis adenylate cyclase 9 0.0077 0.0342 0.0333
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0343 0.0334
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0371 0.0683
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0608 0.0705
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0343 0.0393
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0205 0.1048 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0234 0.0265
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0052 0.0338
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0099 0.0509
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0099 0.019
Trichomonas vaginalis ran, putative 0.0022 0.0033 0.006
Mycobacterium ulcerans beta-lactamase 0.0038 0.0123 0.1187
Onchocerca volvulus 0.0535 0.2882 0.5199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0371 0.0683
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0535 0.2882 0.3385
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0149 0.0293
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0182 0.0204
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0045 0.0082
Brugia malayi hypoxia-induced factor 1 0.0151 0.075 0.157
Loa Loa (eye worm) hypothetical protein 0.0043 0.0149 0.0293
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0875 0.4768 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0108 0.0116
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0607 0.6697
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.012 0.0625
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0123 0.0641
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0083 0.0714
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0205 0.1048 0.5861
Schistosoma mansoni hypothetical protein 0.0535 0.2882 0.3385
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.005 0.0186 0.0389
Brugia malayi larval opioid receptor 0.0535 0.2882 0.6043
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0099 0.0509
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0535 0.2882 0.2876
Brugia malayi phosphofructokinase 0.0115 0.0548 0.1147
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0083 0.5
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0123 0.0114
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0079 0.0395
Echinococcus granulosus hypothetical protein 0.0535 0.2882 0.3385
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0535 0.2882 0.3385
Brugia malayi beta-lactamase family protein 0.0038 0.0123 0.0255
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0052 0.0338
Loa Loa (eye worm) adenylyl cyclase 3 0.0183 0.0928 0.1931
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0064 0.0267 0.0491
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0033 0.0028
Onchocerca volvulus 0.0052 0.0199 0.0164
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0083 0.5324
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0535 0.2882 0.3385
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0099 0.0509
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0064 0.0267 0.0491
Schistosoma mansoni loxhd1 0.0043 0.0149 0.0164
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0099 0.0919
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0052 0.0375
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Echinococcus granulosus G protein coupled receptor 139 0.0535 0.2882 0.3385
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.003 0.0079 0.0147
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0123 0.0134
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0052 0.0408
Brugia malayi Serotonin receptor 0.0535 0.2882 0.6043
Echinococcus multilocularis g protein coupled receptor 0.0535 0.2882 0.2876
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0234 0.0265
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0535 0.2882 0.3385
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0052 0.0375
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.1782 1
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.003 0.0079 0.0395
Plasmodium falciparum importin beta, putative 0.003 0.0076 0.4795
Plasmodium vivax importin-beta 2, putative 0.003 0.0076 0.0643
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0052 0.0375
Echinococcus granulosus dna polymerase eta 0.0019 0.0019 0.0011
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0535 0.2882 0.6043
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0083 0.0375 0.0689
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.015 0.0166
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Schistosoma mansoni neuropeptide receptor 0.0535 0.2882 0.3385
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.005 0.0186 0.0209
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0019 0.0077
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0174 0.0878 0.1826
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0083 0.0375 0.2062
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0535 0.2882 0.6037
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Onchocerca volvulus 0.0535 0.2882 0.5199
Schistosoma mansoni neuropeptide f receptor 76f 0.0535 0.2882 0.3385
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0145
Giardia lamblia Kinase, CMGC MAPK 0.0114 0.0545 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0083 0.0375 0.2062
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0045 0.0201
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0112 0.0232
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Onchocerca volvulus 0.0535 0.2882 0.5199
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0123 0.0907
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0019 0.0054
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0548 1
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0123 0.0226
Brugia malayi sulfakinin receptor protein 0.0535 0.2882 0.6043
Onchocerca volvulus 0.0535 0.2882 0.5199
Leishmania major cAMP-specific phosphodiesterase, putative 0.003 0.0079 0.0395
Echinococcus multilocularis serotonin receptor 0.0535 0.2882 0.2876
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0052 0.0338
Leishmania major hypothetical protein, conserved 0.0038 0.0123 0.0641
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0535 0.2882 0.3385
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0052 0.0338
Entamoeba histolytica hypothetical protein 0.0024 0.0045 0.0493
Brugia malayi PAS domain containing protein 0.0049 0.0182 0.038
Echinococcus granulosus adenylate cyclase type IX 0.0109 0.0516 0.0597
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0607 0.0704
Echinococcus granulosus biogenic amine 5HT receptor 0.0535 0.2882 0.3385
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0607 0.575
Brugia malayi follicle stimulating hormone receptor 0.0766 0.4163 0.8731
Brugia malayi beta-lactamase family protein 0.0038 0.0123 0.0255
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0076 0.0377
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0052 0.0338
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0083 0.0371 0.0427
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.019 0.0968 0.2015
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0607 0.0704
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0548 0.0635
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0083 0.5
Echinococcus multilocularis g-protein coupled receptor 0.0535 0.2882 0.2876
Echinococcus multilocularis RUN 0.0043 0.0149 0.014
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.003 0.0079 0.0145
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0083 0.0371 0.2043
Schistosoma mansoni lamin 0.0056 0.022 0.0248
Onchocerca volvulus 0.0043 0.0149 0.0069
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0033 0.0132
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0371 0.2043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0079 0.0145
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0079 0.0145
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0317 0.167 0.3489
Toxoplasma gondii ABC1 family protein 0.0038 0.0123 0.1094
Echinococcus granulosus GPCR family 2 0.0035 0.0108 0.0116
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0019 0.0077
Brugia malayi G-protein coupled receptor 0.0535 0.2882 0.6043
Mycobacterium tuberculosis Conserved protein 0.0038 0.0123 0.0907
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Onchocerca volvulus 0.0535 0.2882 0.5199
Brugia malayi beta-lactamase 0.0038 0.0123 0.0255
Echinococcus granulosus neuropeptides capa receptor 0.0535 0.2882 0.3385
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.015 0.0141
Echinococcus granulosus intermediate filament protein 0.0056 0.022 0.0248
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0052 0.0375
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0052 0.0375
Toxoplasma gondii NAC domain-containing protein 0.0038 0.012 0.1066
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0052 0.0375
Schistosoma mansoni neuropeptide receptor 0.0535 0.2882 0.3385
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0535 0.2882 0.2876
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0083 0.0375 0.0431
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0608 0.0705
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0535 0.2882 0.2876
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0535 0.2882 0.2876
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Schistosoma mansoni biogenic amine (5HT) receptor 0.0535 0.2882 0.3385
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0114 0.0545 0.5158
Mycobacterium tuberculosis Conserved hypothetical protein 0.0177 0.0897 0.708
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0123 0.1094
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0052 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0607 0.4767
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.0968 0.113
Loa Loa (eye worm) hypothetical protein 0.0043 0.0149 0.0293
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0083 0.5324
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0123 0.0907
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0083 0.0375 0.2062
Echinococcus multilocularis dna polymerase eta 0.0019 0.0019 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0535 0.2882 0.6037
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.003 0.0079 0.0082
Schistosoma mansoni histamine h1 receptor 0.0535 0.2882 0.3385
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Echinococcus granulosus adenylate cyclase 9 0.0077 0.0342 0.0392
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0083 0.0714
Onchocerca volvulus 0.0535 0.2882 0.5199
Brugia malayi Pre-SET motif family protein 0.0125 0.0608 0.1273
Brugia malayi Inositol-1 0.0043 0.015 0.0313
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis adenylate cyclase type IX 0.0109 0.0516 0.0507
Onchocerca volvulus 0.0535 0.2882 0.5199
Echinococcus granulosus tm gpcr rhodopsin 0.0535 0.2882 0.3385
Schistosoma mansoni inositol monophosphatase 0.0043 0.015 0.0166
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0125 0.0608 0.0599
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.015 0.0797
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0535 0.2882 0.2876
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0371 0.2043
Brugia malayi hypothetical protein 0.0128 0.0625 0.1308
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.019 0.0968 0.096
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.015 0.0797
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.012 0.022
Mycobacterium tuberculosis Conserved protein 0.0038 0.0123 0.0907
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0052 0.0338
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0545 0.1002
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0145
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0548 0.1008
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0108 0.0223
Entamoeba histolytica hypothetical protein 0.0038 0.012 0.191
Trypanosoma brucei protein kinase, putative 0.0114 0.0545 0.3023
Echinococcus multilocularis muscleblind protein 0.0174 0.0878 0.087
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0545 0.0632
Plasmodium falciparum cGMP-specific phosphodiesterase 0.003 0.0079 0.5021
Mycobacterium ulcerans hypothetical protein 0.0038 0.0123 0.1187
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.002
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0033 0.0023
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0145
Echinococcus granulosus 7TM GPCR rhodopsin 0.0535 0.2882 0.3385
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0052 0.0239
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0535 0.2882 0.3385
Onchocerca volvulus 0.0535 0.2882 0.5199
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0054
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Loa Loa (eye worm) hypothetical protein 0.0125 0.0608 0.1258
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.003 0.0079 0.0082
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Echinococcus granulosus single minded 2 0.0036 0.0112 0.0121
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0052 0.0338
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0083 0.0153
Loa Loa (eye worm) hypothetical protein 0.0038 0.0123 0.0239
Schistosoma mansoni amine GPCR 0.0535 0.2882 0.3385
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0205 0.1048 0.5861
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Schistosoma mansoni biogenic amine receptor 0.0535 0.2882 0.3385
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.015 0.0277
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0123 0.0239
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0083 0.122
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus dna polymerase kappa 0.0019 0.0019 0.0011
Schistosoma mansoni hypothetical protein 0.0025 0.0052 0.005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.006 0.006
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0083 0.1227
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0116
Brugia malayi putative neuropeptide receptor NPR1 0.0535 0.2882 0.6043
Echinococcus multilocularis mitogen activated protein kinase 3 0.0114 0.0545 0.0537
Echinococcus granulosus tm gpcr rhodopsin 0.0535 0.2882 0.3385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.1782 1
Brugia malayi latrophilin 2 splice variant baaae 0.0076 0.0335 0.0701
Plasmodium falciparum phosphodiesterase gamma, putative 0.003 0.0079 0.5021
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0123 0.0226
Echinococcus granulosus neuropeptides capa receptor 0.0535 0.2882 0.3385
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus peptide allatostatin:somatostatin 0.0535 0.2882 0.3385
Echinococcus granulosus tm gpcr rhodopsin 0.0535 0.2882 0.3385
Schistosoma mansoni neuropeptide F-like receptor 0.0535 0.2882 0.3385
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.015 0.2486
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.0545 0.3023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0112 0.0531 0.1098
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.003 0.0079 0.007
Echinococcus granulosus geminin 0.0198 0.1008 0.1177
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0205 0.1048 1
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0052 0.0375
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.032 0.0367
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.019 0.0968 0.2028
Brugia malayi Dopamine receptor 0.0535 0.2882 0.6043
Schistosoma mansoni inositol monophosphatase 0.0043 0.015 0.0166
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0535 0.2882 0.2876
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0033 0.0225
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0535 0.2882 0.6037
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0159 0.0797 0.4442
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0052 0.0375
Leishmania major cytochrome p450-like protein 0.0025 0.0052 0.0239
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.5021
Echinococcus granulosus lamin 0.0056 0.022 0.0248
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0099 0.019
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0052 0.0375
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.015 0.0277
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0009 0.0017
Brugia malayi isocitrate dehydrogenase 0.0018 0.0009 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0548 0.1008
Schistosoma mansoni lipoxygenase 0.0193 0.0982 0.1146
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0083 0.0371 0.0427
Onchocerca volvulus Neuropeptide F receptor homolog 0.0535 0.2882 0.5199
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Echinococcus multilocularis sex peptide receptor 0.0535 0.2882 0.2876
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0019 0.0001
Brugia malayi Serotonin receptor 0.0535 0.2882 0.6043
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.003 0.0079 0.0163
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0083 0.0371 0.6659
Schistosoma mansoni amine GPCR 0.0535 0.2882 0.3385
Brugia malayi MH2 domain containing protein 0.0128 0.0624 0.1306
Echinococcus multilocularis g protein coupled receptor 0.0535 0.2882 0.2876
Schistosoma mansoni hypothetical protein 0.0076 0.0335 0.0384
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0112 0.0531 0.1112
Mycobacterium leprae Probable lipase LipE 0.0038 0.0123 0.1967
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Plasmodium vivax SET domain protein, putative 0.0125 0.0608 0.5761
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0535 0.2882 0.6043
Entamoeba histolytica Ran family GTPase 0.0022 0.0033 0.026
Echinococcus multilocularis G-protein coupled receptor, putative 0.0535 0.2882 0.2876
Schistosoma mansoni biogenic amine (5HT) receptor 0.0535 0.2882 0.3385
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0548 0.0635
Schistosoma mansoni DNA polymerase eta 0.0019 0.0019 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0535 0.2882 0.2876
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0207 0.038
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Loa Loa (eye worm) hypothetical protein 0.0027 0.006 0.0107
Schistosoma mansoni myosin xvIII 0.0535 0.2882 0.3385
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.019 0.0968 0.113
Echinococcus multilocularis neuropeptide FF receptor 2 0.0535 0.2882 0.2876
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0083 0.0153
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0673
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Brugia malayi RE15519p 0.0535 0.2882 0.6043
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0033 0.0132
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Loa Loa (eye worm) neuropeptide F receptor 0.0535 0.2882 0.6037
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0766 0.4163 0.8729
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Brugia malayi cytochrome P450 0.0025 0.0052 0.0105
Plasmodium vivax basic transcription factor 3b, putative 0.0038 0.012 0.1066
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0535 0.2882 0.3385
Schistosoma mansoni polycystin 1-related 0.0043 0.0149 0.0164
Leishmania major importin beta-1 subunit, putative 0.0024 0.0045 0.0201
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Schistosoma mansoni amine GPCR 0.0535 0.2882 0.3385
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0149 0.0164
Brugia malayi Cytochrome P450 family protein 0.0034 0.0099 0.0206
Echinococcus granulosus rhodopsin orphan GPCR 0.0535 0.2882 0.3385
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0079 0.0163
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0205 0.1048 0.104
Echinococcus multilocularis fmrfamide receptor 0.0535 0.2882 0.2876
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0234 0.0265
Schistosoma mansoni hypothetical protein 0.0198 0.1008 0.1177
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0535 0.2882 0.2876
Schistosoma mansoni amine GPCR 0.0535 0.2882 0.3385
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0114 0.0545 0.1126
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0535 0.2882 0.3385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Echinococcus granulosus neuropeptide Y receptor 0.0535 0.2882 0.3385
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0125 0.0608 0.0705
Echinococcus granulosus microtubule associated protein 2 0.1546 0.8497 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0149 0.1341
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0545 0.1002
Plasmodium falciparum cGMP-specific phosphodiesterase 0.003 0.0079 0.5021
Echinococcus granulosus ubiquitin specific protease 41 0.0083 0.0371 0.0427
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.0207
Onchocerca volvulus 0.0535 0.2882 0.5199
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Brugia malayi hypothetical protein 0.0074 0.032 0.067
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Brugia malayi Cytochrome P450 family protein 0.0025 0.0052 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0548 1
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis transcription factor btf3 0.0038 0.012 0.0111
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0149 1
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Brugia malayi hypothetical protein 0.0254 0.1322 0.2771
Echinococcus granulosus 7tm_1 domain containing protein 0.0535 0.2882 0.3385
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.006 0.0051
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0019 0.0034
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.032 0.0312
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0149 0.014
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0535 0.2882 0.2876
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.5021
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0548 0.1008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0535 0.2882 0.3385
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0114 0.0545 0.3023
Brugia malayi Muscleblind-like protein 0.0174 0.0878 0.184
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0079 0.0395
Echinococcus granulosus g protein coupled receptor 0.0535 0.2882 0.3385
Brugia malayi Cytochrome P450 family protein 0.0034 0.0099 0.0206
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0083 0.0375 0.0689
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0033 0.0225
Schistosoma mansoni cytochrome P450 0.0025 0.0052 0.005
Echinococcus multilocularis neuropeptide Y receptor 0.0535 0.2882 0.2876
Echinococcus granulosus RUN 0.0043 0.0149 0.0164
Brugia malayi neuropeptide F receptor 0.0535 0.2882 0.6043
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.003 0.0079 0.0395
Loa Loa (eye worm) hypothetical protein 0.0335 0.177 0.3701
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0535 0.2882 0.2876
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0234 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0052 0.0338
Onchocerca volvulus 0.0535 0.2882 0.5199
Brugia malayi Pre-SET motif family protein 0.0875 0.4768 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0174 0.0932
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Brugia malayi G-protein coupled receptor 0.0535 0.2882 0.6043
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0147
Loa Loa (eye worm) hypothetical protein 0.0174 0.0878 0.1826
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0123 0.0907
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0123 0.0134
Loa Loa (eye worm) hypothetical protein 0.0056 0.022 0.0442
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0033 0.0261
Onchocerca volvulus 0.0043 0.0149 0.0069
Schistosoma mansoni hypothetical protein 0.0043 0.0149 0.0164
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0019 0.0001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0108 0.0207
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0186 0.0343
Schistosoma mansoni rab6-interacting 0.0043 0.0149 0.0164
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.022 0.0442
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0079 0.0395
Giardia lamblia Hypothetical protein 0.003 0.0079 0.1147
Mycobacterium leprae Conserved hypothetical protein 0.0025 0.0052 0.0621
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0205 0.1048 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0052 0.0338
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0535 0.2882 0.2876
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.005 0.0186 0.0343
Toxoplasma gondii hypothetical protein 0.0053 0.0207 0.1902
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0149 0.014
Echinococcus multilocularis neuropeptide receptor A26 0.0535 0.2882 0.2876
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0045 0.0082
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0052 0.0338
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0545 0.1002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.015 0.0277
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0019 0.0011
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0548 0.1133
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Leishmania major hypothetical protein, conserved 0.003 0.0079 0.0395
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0114 0.0545 0.3023
Loa Loa (eye worm) hypothetical protein 0.0254 0.1322 0.2759
Echinococcus granulosus snurportin 1 0.0317 0.167 0.1956
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0607 0.6697
Echinococcus multilocularis GPCR, family 2 0.0035 0.0108 0.0098
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0548 0.1008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0019 0.0034
Echinococcus granulosus tachykinin peptides receptor 99D 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus sex peptide receptor 0.0535 0.2882 0.3385
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0079 0.0163
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0019 0.0054
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0149 0.0164
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0624 0.1291
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0371 0.2043
Loa Loa (eye worm) melatonin receptor type 1A 0.0535 0.2882 0.6037
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0268 0.0545
Brugia malayi Cytochrome P450 family protein 0.0064 0.0268 0.0561
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0535 0.2882 0.2876
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0123 0.0907
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0548 0.304
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0083 0.0153
Loa Loa (eye worm) hypothetical protein 0.0038 0.0123 0.0239
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0019 0.0091
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0114 0.0545 0.3023
Echinococcus granulosus mitogen activated protein kinase 3 0.0114 0.0545 0.0632
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Loa Loa (eye worm) hypothetical protein 0.0054 0.0214 0.043
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Leishmania major cytochrome p450-like protein 0.0025 0.0052 0.0239
Leishmania major DNA polymerase eta, putative 0.0019 0.0019 0.0054
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0123 0.0255
Loa Loa (eye worm) hypothetical protein 0.0038 0.0123 0.0239
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0019 0.0054
Schistosoma mansoni hypothetical protein 0.0317 0.167 0.1956
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0535 0.2882 0.6037
Schistosoma mansoni microtubule-associated protein tau 0.1546 0.8497 1
Schistosoma mansoni transcription factor btf3 0.0038 0.012 0.013
Brugia malayi 6-phosphofructokinase 0.0115 0.0548 0.1147
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0083 0.0375 0.2062
Onchocerca volvulus 0.0074 0.0323 0.0397
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Mycobacterium ulcerans lipase LipD 0.0038 0.0123 0.1187
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0108 0.0098
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0112 0.0103
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0079 0.0673
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0052 0.0338
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0586 0.3163 0.3716
Echinococcus multilocularis allatostatin A receptor 0.0535 0.2882 0.2876
Schistosoma mansoni lipoxygenase 0.0116 0.0555 0.0643
Echinococcus multilocularis neuropeptide receptor 0.0535 0.2882 0.2876
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0116
Schistosoma mansoni hypothetical protein 0.0198 0.1008 0.1177
Schistosoma mansoni survival motor neuron protein 0.0052 0.0199 0.0224
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0083 0.0375 0.0366
Entamoeba histolytica hypothetical protein 0.0074 0.032 0.5697
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Echinococcus granulosus g-protein coupled receptor 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0052 0.0338
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0079 0.0395
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0076 0.0141
Echinococcus granulosus lamin dm0 0.0056 0.022 0.0248
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0586 0.3163 0.3716
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0535 0.2882 0.3385
Mycobacterium leprae putative cytochrome p450 0.0025 0.0052 0.0621
Loa Loa (eye worm) inositol-1 0.0043 0.015 0.0297
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0054
Echinococcus granulosus dro:myosuppressin receptor 0.0535 0.2882 0.3385
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0548 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0608 0.0705
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.003 0.0079 0.007
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0205 0.1048 0.5861
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0123 0.0641
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0797 0.4442
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0123 0.0226
Brugia malayi Importin beta-1 subunit 0.003 0.0076 0.0157
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.005 0.0186 0.0209
Trypanosoma brucei unspecified product 0.0019 0.0019 0.0054
Onchocerca volvulus 0.0535 0.2882 0.5199
Brugia malayi intermediate filament protein 0.0056 0.022 0.0458
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0234 0.0225
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0083 0.0153
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.003 0.0079 0.0082
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0052 0.0375
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus multilocularis survival motor neuron protein 1 0.0254 0.1322 0.1314
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0205 0.1048 0.5861
Onchocerca volvulus 0.0038 0.0123 0.0021
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0052 0.0239
Loa Loa (eye worm) hypothetical protein 0.0112 0.0531 0.1098
Echinococcus multilocularis lamin dm0 0.0056 0.022 0.0211
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0052 0.0239
Schistosoma mansoni hypothetical protein 0.0052 0.0199 0.0224
Mycobacterium tuberculosis Conserved protein 0.0038 0.0123 0.0907
Loa Loa (eye worm) ICD-1 protein 0.0038 0.012 0.0233
Schistosoma mansoni alpha-1 adrenergic receptor 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.015 0.0797
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0548 0.304
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.003 0.0079 0.0082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Schistosoma mansoni opsin-like receptor 0.0535 0.2882 0.3385
Plasmodium falciparum phosphodiesterase delta, putative 0.003 0.0079 0.5021
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0076 0.0158
Loa Loa (eye worm) hypothetical protein 0.0038 0.0123 0.0239
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Brugia malayi Doublecortin family protein 0.0043 0.0149 0.0309
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0083 0.0714
Brugia malayi Adenylyl cyclase protein 0.0077 0.0342 0.0714
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0607 0.0598
Entamoeba histolytica hypothetical protein 0.0074 0.032 0.5697
Onchocerca volvulus 0.0535 0.2882 0.5199
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0052 0.0338
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0052 0.0375
Loa Loa (eye worm) hypothetical protein 0.0038 0.0123 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0079 0.0395
Schistosoma mansoni neuropeptide F-like receptor 0.0535 0.2882 0.3385
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0535 0.2882 0.6043
Brugia malayi G protein-coupled receptor 0.0535 0.2882 0.6043
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0083 0.0371 0.0776
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0083 0.0375 0.2062
Brugia malayi 6-phosphofructokinase 0.0115 0.0548 0.1147
Schistosoma mansoni opsin-like receptor 0.0535 0.2882 0.3385
Echinococcus multilocularis fmrfamide receptor 0.0535 0.2882 0.2876
Leishmania major hypothetical protein, conserved 0.003 0.0079 0.0395
Echinococcus granulosus neuropeptide FF receptor 2 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0052 0.0338
Trichomonas vaginalis set domain proteins, putative 0.0995 0.5439 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0149 0.014
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.032 0.0367
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0083 0.0371 0.0427
Echinococcus multilocularis 0.0025 0.0052 0.0042
Echinococcus granulosus Solute carrier family 22 5 0.1012 0.5533 0.6509
Onchocerca volvulus 0.0535 0.2882 0.5199
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0234 0.0473
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.003 0.0079 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0375 0.0689
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0535 0.2882 0.3385
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0112 0.1061
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0083 0.0371 0.0363
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0116
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0019 0.002
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0052 0.0375
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0548 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0624 0.1291
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0535 0.2882 0.3385
Brugia malayi neuropeptide F receptor 0.0535 0.2882 0.6043
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0123 0.0907
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.014
Leishmania major basic transcription factor 3a, putative 0.0038 0.012 0.0625
Echinococcus multilocularis ubiquitin specific protease 41 0.0083 0.0371 0.0363
Brugia malayi Dopamine receptor protein 2 0.0535 0.2882 0.6043
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0232 0.1256
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0548 1
Echinococcus multilocularis mitogen activated protein kinase 0.0114 0.0545 0.0537
Echinococcus granulosus neuropeptide receptor 0.0535 0.2882 0.3385
Echinococcus multilocularis geminin 0.0198 0.1008 0.1
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0535 0.2882 0.3385
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.1263 1
Loa Loa (eye worm) TYRA-2 protein 0.0535 0.2882 0.6037
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Schistosoma mansoni neuropeptide receptor 0.0535 0.2882 0.3385
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0149 0.0164
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0108 0.0116
Trypanosoma brucei transcription factor BTF3, putative 0.0038 0.012 0.0625
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0548 0.43
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0019 0.0011
Onchocerca volvulus 0.0125 0.0608 0.0931
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.0968 0.113
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0207 0.038
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.015 0.15
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0033 0.0066
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0125 0.0927
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0548 0.1133
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0052 0.0375
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0123 0.0226
Echinococcus multilocularis G protein coupled receptor 139 0.0535 0.2882 0.2876
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0114 0.0545 0.3023
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0079 0.0145
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0083 0.0153
Echinococcus multilocularis musashi 0.0056 0.022 0.0211
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0077 0.0342 0.0431
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0033 0.1675
Brugia malayi ORL1-like opioid receptor 0.0535 0.2882 0.6043
Onchocerca volvulus 0.0996 0.544 1
Loa Loa (eye worm) G-protein coupled receptor 0.0535 0.2882 0.6037
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0083 0.0375 0.0689
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0054
Schistosoma mansoni importin beta-1 0.003 0.0076 0.0079
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0174 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0207 0.038
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0052 0.0338
Loa Loa (eye worm) cytochrome P450 0.0025 0.0052 0.0089
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0083 0.0153
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0079 0.0145
Loa Loa (eye worm) PDE1B protein 0.0586 0.3163 0.6628
Schistosoma mansoni biogenic amine receptor 0.0535 0.2882 0.3385
Trichomonas vaginalis esterase, putative 0.0038 0.0123 0.0226
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0019 0.0091
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0095
Onchocerca volvulus 0.0056 0.022 0.0202
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.015 0.0797
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0535 0.2882 0.3385
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0186 0.0343
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0083 0.0375 0.0689
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0019 0.0037
Schistosoma mansoni biogenic amine receptor 0.0535 0.2882 0.3385
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0052 0.0375
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0535 0.2882 0.6043
Schistosoma mansoni intermediate filament proteins 0.0056 0.022 0.0248
Echinococcus granulosus muscleblind protein 0.0174 0.0878 0.1024
Schistosoma mansoni adenoreceptor 0.0535 0.2882 0.3385
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0052 0.0375
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Echinococcus granulosus mitogen activated protein kinase 0.0114 0.0545 0.0632
Schistosoma mansoni lamin 0.0056 0.022 0.0248
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.0019 0.0076
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0199 0.0415
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0108 0.0223
Loa Loa (eye worm) hypothetical protein 0.0083 0.0371 0.0761
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0548 0.0635
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0052 0.0239
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Brugia malayi hypothetical protein 0.0535 0.2882 0.6043
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0052 0.0375
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0607 0.337
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0337 0.1782 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0125 0.0608 0.0705
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0586 0.3163 0.3157
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Brugia malayi AKH receptor 0.0535 0.2882 0.6043
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0052 0.0375
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.0968 0.113
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0797 0.4442
Echinococcus multilocularis rhodopsin orphan GPCR 0.0535 0.2882 0.2876
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0548 0.054
Echinococcus granulosus biogenic amine 5HT receptor 0.0535 0.2882 0.3385
Giardia lamblia hypothetical protein 0.003 0.0079 0.1147
Brugia malayi Tachykinin-like peptides receptor 99D 0.0535 0.2882 0.6043
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.003 0.0079 0.0395
Schistosoma mansoni opsin-like receptor 0.0535 0.2882 0.3385
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0083 0.0371 0.0363
Brugia malayi GnHR receptor homolog 0.0535 0.2882 0.6043
Schistosoma mansoni amine GPCR 0.0535 0.2882 0.3385
Leishmania major cytochrome p450-like protein 0.0034 0.0099 0.0509
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.019 0.0968 0.113
Onchocerca volvulus 0.0535 0.2882 0.5199
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0076 0.0643
Echinococcus granulosus orexin receptor type 2 0.0535 0.2882 0.3385
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0034
Toxoplasma gondii hypothetical protein 0.0019 0.0019 0.0091
Echinococcus multilocularis neuropeptide Y receptor 0.0535 0.2882 0.2876
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0193 0.0982 0.1146
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0535 0.2882 0.3385
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.015 0.5
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.003 0.0079 0.007
Echinococcus multilocularis dro:myosuppressin receptor 0.0535 0.2882 0.2876
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0019 0.001
Echinococcus multilocularis g protein coupled receptor 0.0535 0.2882 0.2876
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.012 0.022
Loa Loa (eye worm) G-protein coupled receptor 0.0535 0.2882 0.6037
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0147
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0123 0.0907
Mycobacterium ulcerans hypothetical protein 0.0177 0.0897 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Echinococcus granulosus neuropeptide receptor 0.0535 0.2882 0.3385
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.003 0.0079 0.0082
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0083 0.0153
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0535 0.2882 0.3385
Loa Loa (eye worm) hypothetical protein 0.0164 0.082 0.1704
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.005 0.0186 0.0389
Brugia malayi beta-NAC-like protein 0.0038 0.012 0.0249
Loa Loa (eye worm) hypothetical protein 0.0535 0.2882 0.6037
Echinococcus granulosus alpha 1A adrenergic receptor 0.0535 0.2882 0.3385
Schistosoma mansoni rab6-interacting 0.0043 0.0149 0.0164
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0079 0.0395
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0079 0.0673
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0535 0.2882 0.3385
Brugia malayi Melatonin receptor type 1A 0.0535 0.2882 0.6043

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.