Detailed information for compound 911577

Basic information

Technical information
  • TDR Targets ID: 911577
  • Name: ethyl 1,5-bis(4-methylphenyl)-4,6-dioxo-3a,6a -dihydropyrrolo[3,4-d]pyrazole-3-carboxylate
  • MW: 391.42 | Formula: C22H21N3O4
  • H donors: 0 H acceptors: 3 LogP: 3.8 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1=NN(C2C1C(=O)N(C2=O)c1ccc(cc1)C)c1ccc(cc1)C
  • InChi: 1S/C22H21N3O4/c1-4-29-22(28)18-17-19(25(23-18)16-11-7-14(3)8-12-16)21(27)24(20(17)26)15-9-5-13(2)6-10-15/h5-12,17,19H,4H2,1-3H3
  • InChiKey: HWABDGNIOJVAKM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,5-bis(4-methylphenyl)-4,6-dioxo-3a,6a-dihydropyrrolo[3,4-d]pyrazole-3-carboxylic acid ethyl ester
  • 4,6-diketo-1,5-bis(4-methylphenyl)-3a,6a-dihydropyrrolo[3,4-d]pyrazole-3-carboxylic acid ethyl ester
  • ST5433475
  • Oprea1_714146

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0026 0.0078 0.0199
Brugia malayi G-protein coupled receptor 0.0026 0.0078 0.0199
Echinococcus granulosus neuroglian 0.0031 0.0115 0.0168
Echinococcus granulosus sphingomyelin synthase protein 1 0.0034 0.0142 0.0211
Schistosoma mansoni bromodomain containing protein 0.002 0.0033 0.0027
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Echinococcus granulosus alpha 1A adrenergic receptor 0.0026 0.0078 0.0112
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0026 0.0616
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0026 1
Trichomonas vaginalis cgi-62, putative 0.0034 0.0142 0.34
Brugia malayi hypothetical protein 0.0025 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0078 0.0112
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0076 0.0455 0.0696
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0026 0.0067
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.008 0.048 0.5
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0292 0.0741
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0025 0.0071 0.0101
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0099 0.0252
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0469 0.3391 0.3387
Brugia malayi larval opioid receptor 0.0026 0.0078 0.0199
Brugia malayi ShTK domain containing protein 0.0093 0.0577 0.1467
Echinococcus granulosus hypothetical protein 0.0026 0.0078 0.0112
Echinococcus granulosus zinc finger protein 0.002 0.0033 0.0041
Schistosoma mansoni zinc finger protein 0.002 0.0033 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.008 0.048 0.0735
Brugia malayi hypothetical protein 0.0025 0.0072 0.0183
Toxoplasma gondii hypothetical protein 0.008 0.048 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0011 0.0027
Echinococcus granulosus somatostatin receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Treponema pallidum sodium- and chloride- dependent transporter 0.0469 0.3391 0.5
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0026 0.1465
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0026 0.0078 0.0072
Schistosoma mansoni amine GPCR 0.0026 0.0078 0.0072
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.005 0.0126
Brugia malayi mbt repeat family protein 0.0541 0.3935 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0026 0.1476
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0972 0.2471
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus multilocularis Sterile alpha motif SAM 0.0034 0.0142 0.0211
Echinococcus multilocularis polyhomeotic protein 2 0.0034 0.0142 0.0211
Echinococcus granulosus pdz domain containing protein 0.0034 0.0142 0.0211
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0078 0.0112
Schistosoma mansoni septate junction protein 0.0018 0.0022 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Loa Loa (eye worm) TK protein kinase 0.0017 0.0011 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Onchocerca volvulus 0.0017 0.0009 0.0024
Schistosoma mansoni cell adhesion molecule 0.0018 0.0022 0.0016
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0026 0.0078 0.0112
Echinococcus granulosus hemicentin 1 0.0018 0.0022 0.0025
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0025 0.0072 0.0183
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0018 0.0022 0.0025
Echinococcus granulosus defective proboscis extension response 0.0018 0.0021 0.0023
Loa Loa (eye worm) AIDA-1b 0.0034 0.0142 0.0361
Echinococcus multilocularis roundabout 2 0.0018 0.0022 0.0025
Brugia malayi SET domain containing protein 0.0017 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0159 0.0405
Echinococcus granulosus neuropeptide receptor A26 0.0026 0.0078 0.0112
Schistosoma mansoni amine GPCR 0.0026 0.0078 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Trypanosoma cruzi Kinesin-13 5, putative 0.0034 0.0142 1
Onchocerca volvulus 0.0054 0.029 0.0737
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0026 0.0078 0.0199
Leishmania major DNA polymerase eta, putative 0.0019 0.0026 1
Brugia malayi hypothetical protein 0.0025 0.0072 0.0183
Echinococcus granulosus histone acetyltransferase MYST2 0.0147 0.0982 0.1517
Schistosoma mansoni polyhomeotic 0.0034 0.0142 0.0136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Brugia malayi Cation transporter family protein 0.0054 0.0292 0.0741
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0054 0.0292 0.0741
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.048 0.0474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Schistosoma mansoni hypothetical protein 0.0034 0.0142 0.0136
Echinococcus multilocularis dnaJ subfamily B 0.0267 0.188 0.2912
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0123 0.0805 0.08
Echinococcus multilocularis serotonin receptor 0.0026 0.0078 0.0112
Schistosoma mansoni hypothetical protein 0.0026 0.0078 0.0072
Onchocerca volvulus 0.0026 0.0078 0.0199
Echinococcus granulosus serotonin transporter 0.0469 0.3391 0.5259
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0417 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0018 0.0022 0.0025
Onchocerca volvulus 0.008 0.048 0.1219
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.048 0.0474
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0078 0.0072
Echinococcus multilocularis liprin alpha 2 0.0034 0.0142 0.0211
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Schistosoma mansoni bromodomain containing protein 0.002 0.0033 0.0027
Onchocerca volvulus 0.0054 0.0292 0.0741
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0026 0.0078 0.0112
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Echinococcus multilocularis serotonin transporter 0.0469 0.3391 0.5259
Loa Loa (eye worm) hypothetical protein 0.0469 0.3391 0.8618
Echinococcus granulosus g-protein coupled receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0018 0.0022 0.0057
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0054 0.0292 0.0443
Schistosoma mansoni titin 0.0018 0.0022 0.0016
Brugia malayi G protein-coupled receptor 0.0026 0.0078 0.0199
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0026 0.0078 0.0072
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.002 0.0033 0.0041
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0 0.5
Echinococcus multilocularis lachesin 0.0018 0.0022 0.0025
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0018 0.0022 0.0057
Schistosoma mansoni cell adhesion molecule 0.0018 0.0022 0.0016
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0093 0.0577 0.1467
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0072 0.0183
Brugia malayi Serotonin receptor 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0123 0.0805 0.1242
Brugia malayi PHD-finger family protein 0.002 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Brugia malayi Tachykinin-like peptides receptor 99D 0.0026 0.0078 0.0199
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0054
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.048 0.1219
Echinococcus granulosus tumor suppressor p53 binding protein 1 0.0321 0.2288 0.3545
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0147 0.0982 0.1517
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0078 0.0112
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Onchocerca volvulus 0.0034 0.0142 0.0361
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0054 0.0292 0.0741
Brugia malayi Prion-like- 0.0018 0.0022 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0078 0.0199
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0093 0.0577 0.1467
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0248 0.0629
Onchocerca volvulus 0.0026 0.0078 0.0199
Toxoplasma gondii hypothetical protein 0.0025 0.0072 0.1393
Loa Loa (eye worm) hypothetical protein 0.0093 0.0577 0.1467
Loa Loa (eye worm) melatonin receptor type 1A 0.0026 0.0078 0.0199
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0034 0.0142 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0443 0.3196 0.8123
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0204 0.4891
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.0078 0.0112
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0026 0.0078 0.0112
Schistosoma mansoni DNA polymerase eta 0.0019 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) norepinephrine transporter 0.0469 0.3391 0.8618
Brugia malayi bicaudal-C 0.0034 0.0142 0.0361
Brugia malayi hypothetical protein 0.0018 0.0021 0.0054
Trypanosoma cruzi Kinesin-13 5, putative 0.0034 0.0142 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0123 0.0805 0.2047
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.048 0.1219
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0026 0.0078 0.0199
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.048 0.0735
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.048 0.0474
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0028 0.0091 0.0131
Onchocerca volvulus 0.0093 0.0577 0.1467
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0078 0.0112
Onchocerca volvulus Tankyrase homolog 0.0034 0.0142 0.0361
Brugia malayi PHD-finger family protein 0.0016 0.0006 0.0016
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.008 0.048 0.0735
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.0022 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0147 0.0982 0.2497
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0026 0.1465
Schistosoma mansoni chromobox protein 0.0193 0.1332 0.1326
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Brugia malayi G protein-coupled receptor F59B2.13 0.0026 0.0078 0.0199
Echinococcus granulosus roundabout 2 0.0018 0.0022 0.0025
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0178 1
Echinococcus granulosus glycine receptor subunit beta 0.0054 0.0292 0.0443
Brugia malayi Dopamine receptor protein 2 0.0026 0.0078 0.0199
Schistosoma mansoni biogenic amine receptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0078 0.0112
Echinococcus granulosus SAM and MBT domain containing protein 0.047 0.3404 0.5279
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0016 0.0006 0.0016
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0054 0.0292 0.0741
Onchocerca volvulus Neuropeptide F receptor homolog 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni alpha-1 adrenergic receptor 0.0026 0.0078 0.0072
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0876 0.6443 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.002 0.0033 0.0041
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0204 0.4182
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0026 0.0078 0.0112
Schistosoma mansoni nAChR subunit 0.0025 0.0072 0.0066
Echinococcus granulosus dro:myosuppressin receptor 0.0026 0.0078 0.0112
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.048 0.0474
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0026 0.1465
Schistosoma mansoni biogenic amine receptor 0.0026 0.0078 0.0072
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni hypothetical protein 0.0033 0.0133 0.0126
Onchocerca volvulus 0.0054 0.0292 0.0741
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0026 0.0078 0.0112
Onchocerca volvulus 0.0026 0.0078 0.0199
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0113 0.0731 0.1125
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0147 0.0982 0.1517
Schistosoma mansoni hypothetical protein 0.0026 0.0078 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.0507 0.0501
Brugia malayi Cation transporter family protein 0.0054 0.0292 0.0741
Trypanosoma cruzi hypothetical protein 0.0034 0.0142 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.048 0.0474
Onchocerca volvulus 0.0093 0.0577 0.1467
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0078 0.0112
Schistosoma mansoni amine GPCR 0.0026 0.0078 0.0072
Brugia malayi AIDA-1b 0.0034 0.0142 0.0361
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0292 0.0443
Loa Loa (eye worm) acetylcholine receptor protein 0.0025 0.0072 0.0183
Loa Loa (eye worm) solute carrier family 6 member 4 0.0469 0.3391 0.8618
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Echinococcus multilocularis histone acetyltransferase myst3 0.0051 0.0264 0.0401
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Schistosoma mansoni spingomyelin synthetase-related 0.0034 0.0142 0.0136
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0026 0.0031
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0078 0.0072
Brugia malayi jmjC domain containing protein 0.0025 0.0071 0.018
Loa Loa (eye worm) GABA receptor subunit 0.0029 0.0104 0.0264
Echinococcus granulosus neuropeptide FF receptor 2 0.0026 0.0078 0.0112
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0204 0.4182
Schistosoma mansoni sex comb on midleg homolog 0.0363 0.2601 0.2597
Echinococcus granulosus roundabout 2 0.0018 0.0022 0.0025
Onchocerca volvulus 0.0026 0.0078 0.0199
Echinococcus multilocularis neuropeptide FF receptor 2 0.0026 0.0078 0.0112
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0469 0.3391 0.8618
Schistosoma mansoni DNAj-like protein 0.0034 0.0142 0.0136
Echinococcus multilocularis Immunoglobulin 0.0018 0.0021 0.0023
Echinococcus granulosus polyhomeotic proximal chromatin protein 0.0034 0.0142 0.0211
Onchocerca volvulus Putative nachr subunit 0.0123 0.0805 0.2047
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0025 0.0072 0.0102
Echinococcus multilocularis lysine specific demethylase 5A 0.0076 0.0454 0.0695
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Loa Loa (eye worm) ACC-1 protein 0.0054 0.0292 0.0741
Echinococcus granulosus polycomb protein SCMH1 0.0363 0.2601 0.4032
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Schistosoma mansoni amine GPCR 0.0026 0.0078 0.0072
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0034 0.0142 0.0211
Loa Loa (eye worm) ShTK domain-containing protein 0.0093 0.0577 0.1467
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) F/Y-rich family protein 0.0016 0.0006 0.0016
Schistosoma mansoni nephrin 0.0018 0.0022 0.0016
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0026 0.0078 0.0199
Onchocerca volvulus 0.0029 0.0104 0.0264
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0078 0.0072
Echinococcus granulosus cpg binding protein 0.0035 0.0146 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0248 0.0629
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0078 0.0112
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0078 0.0112
Schistosoma mansoni jumonji/arid domain-containing protein 0.0092 0.0576 0.057
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0026 0.0078 0.0072
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.048 0.0474
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.048 0.0474
Echinococcus granulosus L aminoadipate semialdehyde 0.0054 0.029 0.0441
Echinococcus multilocularis glycine receptor subunit beta 0.0054 0.0292 0.0443
Onchocerca volvulus 0.0034 0.0142 0.0361
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0122 0.2445
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Brugia malayi hypothetical protein 0.008 0.048 0.1219
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Echinococcus multilocularis sex peptide receptor 0.0026 0.0078 0.0112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0025 0.0072 0.0183
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.008 0.048 0.0735
Loa Loa (eye worm) hypothetical protein 0.0469 0.3391 0.8618
Echinococcus multilocularis G-protein coupled receptor, putative 0.0026 0.0078 0.0112
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0292 0.0285
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0026 0.0078 0.0199
Echinococcus granulosus polyhomeotic protein 2 0.0034 0.0142 0.0211
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Toxoplasma gondii hypothetical protein 0.008 0.048 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Echinococcus granulosus liprin alpha 2 0.0034 0.0142 0.0211
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0054 0.0292 0.0741
Echinococcus multilocularis pdz domain containing protein 0.0034 0.0142 0.0211
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0078 0.0112
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0147 0.0982 0.2497
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0028 0.0091 0.0085
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0078 0.0112
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0178 0.3618
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0123 0.0805 0.08
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0018 0.0022 0.0057
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.048 0.0474
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.0022 0.0025
Loa Loa (eye worm) serotonin transporter b 0.0469 0.3391 0.8618
Onchocerca volvulus 0.0016 0.0006 0.0016
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni sodium-dependent amino acid transporter 0.008 0.048 0.0474
Schistosoma mansoni sodium/chloride dependent transporter 0.0469 0.3391 0.3387
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0292 0.0741
Schistosoma mansoni cell adhesion molecule 0.0018 0.0022 0.0016
Echinococcus granulosus roundabout 2 0.0037 0.0159 0.0238
Schistosoma mansoni acetylcholine receptor subunit beta 0.0025 0.0072 0.0066
Echinococcus granulosus dna polymerase eta 0.0019 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Echinococcus multilocularis G protein coupled receptor 139 0.0026 0.0078 0.0112
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0078 0.0112
Echinococcus granulosus sex peptide receptor 0.0026 0.0078 0.0112
Echinococcus granulosus p2X purinoceptor 4 0.0664 0.4852 0.7529
Brugia malayi Liprin-alpha 2 0.0034 0.0142 0.0361
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0025 0.0072 0.0102
Echinococcus multilocularis Sterile alpha motif type 0.0034 0.0142 0.0211
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Echinococcus multilocularis neuroglian 0.0031 0.0115 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0026 0.0078 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0142 0.34
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Loa Loa (eye worm) jmjC domain-containing protein 0.0136 0.0899 0.2283
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) TYRA-2 protein 0.0026 0.0078 0.0199
Plasmodium falciparum zinc finger protein, putative 0.0017 0.0015 0.0181
Schistosoma mansoni neuropeptide receptor 0.0026 0.0078 0.0072
Schistosoma mansoni cell adhesion molecule 0.0024 0.0066 0.006
Schistosoma mansoni myelin transcription factor 1 myt1 0.0147 0.0982 0.0977
Loa Loa (eye worm) ACC-1 protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0054 0.0292 0.0741
Plasmodium vivax JmjC domain containing protein 0.0029 0.0098 0.1935
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0204 0.0307
Schistosoma mansoni hypothetical protein 0.0321 0.2288 0.2283
Onchocerca volvulus 0.0025 0.0072 0.0183
Loa Loa (eye worm) acetyltransferase 0.0145 0.0972 0.2471
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.047 0.3404 0.34
Onchocerca volvulus 0.0398 0.2866 0.7283
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0066 0.0379 0.0964
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Echinococcus granulosus neuropeptide receptor 0.0026 0.0078 0.0112
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0054 0.0292 0.0443
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0123 0.0805 0.1242
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0011 0.0007
Brugia malayi PHD-finger family protein 0.0016 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0018 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.0182 0.0175
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0204 0.4182
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0029 0.0099 0.0252
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0123 0.0805 0.1242
Echinococcus multilocularis zinc finger protein 0.002 0.0033 0.0041
Schistosoma mansoni nAChR subunit 0.0025 0.0072 0.0066
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0041 0.0105
Echinococcus granulosus neuropeptide s receptor 0.0026 0.0078 0.0112
Echinococcus granulosus tachykinin peptides receptor 99D 0.0026 0.0078 0.0112
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0011 0.0027
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Echinococcus multilocularis dro:myosuppressin receptor 0.0026 0.0078 0.0112
Echinococcus multilocularis p2X purinoceptor 4 0.0664 0.4852 0.7529
Echinococcus multilocularis dna polymerase eta 0.0019 0.0026 0.0031
Plasmodium falciparum transporter, putative 0.008 0.048 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0018 0.0021 0.0023
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0292 0.0285
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.005 0.0043
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0292 0.0443
Echinococcus multilocularis g-protein coupled receptor 0.0026 0.0078 0.0112
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0123 0.0805 0.1242
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0292 0.0443
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Echinococcus granulosus tyrosine protein kinase otk 0.0018 0.0022 0.0025
Onchocerca volvulus 0.0026 0.0078 0.0199
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0178 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Onchocerca volvulus 0.0026 0.0078 0.0199
Onchocerca volvulus 0.0026 0.0078 0.0199
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0076 0.0455 0.1155
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0078 0.0112
Echinococcus granulosus peptide allatostatin:somatostatin 0.0026 0.0078 0.0112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0072 0.0183
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.008 0.048 0.0735
Schistosoma mansoni microtubule-associated protein tau 0.045 0.3252 0.3247
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0054 0.0292 0.0741
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0026 0.0067
Schistosoma mansoni biogenic amine receptor 0.0026 0.0078 0.0072
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0972 0.1501
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0078 0.0072
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0025 0.0072 0.0102
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 24 0.0034 0.0142 1
Brugia malayi Sphingomyelin synthase-related 1 0.0034 0.0142 0.0361
Echinococcus granulosus histone acetyltransferase myst3 0.0051 0.0264 0.0401
Echinococcus multilocularis hemicentin 1 0.0018 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0093 0.0577 0.1467
Brugia malayi Melatonin receptor type 1A 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Onchocerca volvulus 0.0025 0.0072 0.0183
Echinococcus granulosus 7tm_1 domain containing protein 0.0026 0.0078 0.0112
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0026 0.0078 0.0199
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0026 0.0078 0.0112
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.0022 0.0025
Brugia malayi Peroxidasin 0.0018 0.0022 0.0057
Brugia malayi mbt repeat family protein 0.0364 0.2608 0.6628
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0098 0.1935
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0123 0.0805 0.2047
Schistosoma mansoni neuropeptide receptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni adenoreceptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0104 0.0264
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.048 0.1219
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Brugia malayi excitatory GABA receptor EXP-1A 0.0054 0.0292 0.0741
Onchocerca volvulus 0.0016 0.0006 0.0016
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0054 0.029 0.0737
Brugia malayi Fibronectin type III domain containing protein 0.0018 0.0021 0.0054
Onchocerca volvulus 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0469 0.3391 0.8618
Schistosoma mansoni Protein aveugle 0.0034 0.0142 0.0136
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus granulosus contactin 0.0018 0.0022 0.0025
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0025 0.0072 0.0183
Onchocerca volvulus 0.008 0.048 0.1219
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0054 0.0292 0.0285
Loa Loa (eye worm) PHD-finger family protein 0.0016 0.0006 0.0016
Toxoplasma gondii PLU-1 family protein 0.0043 0.0207 0.4241
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0054 0.0292 0.0443
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0037 0.0159 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.0126
Echinococcus multilocularis neuroglian 0.0018 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0067
Echinococcus granulosus neuropeptide receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0123 0.0805 0.1242
Onchocerca volvulus 0.0093 0.0577 0.1467
Echinococcus multilocularis SAM and MBT domain containing protein 0.047 0.3404 0.5279
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.005 0.0043
Loa Loa (eye worm) CHromoDomain protein family member 0.0028 0.0091 0.0231
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Brugia malayi Cation transporter family protein 0.0123 0.0805 0.2047
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0066 0.0093
Trichomonas vaginalis inhibitor of growth, putative 0.0016 0.0006 0.0139
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni tyrosinase precursor 0.0093 0.0577 0.0571
Trypanosoma brucei SAM domain (Sterile alpha motif), putative 0.0034 0.0142 1
Schistosoma mansoni myosin xvIII 0.0026 0.0078 0.0072
Onchocerca volvulus 0.0019 0.0024 0.0062
Loa Loa (eye worm) LGC-31 protein 0.0054 0.0292 0.0741
Schistosoma mansoni tyrosinase precursor 0.0093 0.0577 0.0571
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0054 0.0292 0.0443
Leishmania major DNA polymerase kappa, putative 0.0019 0.0026 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Echinococcus granulosus nAChR subunit 0.0029 0.0104 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.048 0.1219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus granulosus g protein coupled receptor 0.0026 0.0078 0.0112
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0093 0.0577 0.1467
Echinococcus granulosus dnaJ subfamily B 0.0267 0.188 0.2912
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Plasmodium vivax amine transporter, putative 0.008 0.048 1
Echinococcus granulosus twitchin 0.0031 0.0115 0.0168
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0123 0.0805 0.2047
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.048 0.0735
Brugia malayi Shank2E 0.0034 0.0142 0.0361
Echinococcus granulosus serotonin receptor 0.0026 0.0078 0.0112
Brugia malayi RE15519p 0.0026 0.0078 0.0199
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0076 0.0455 0.0696
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0026 1
Onchocerca volvulus 0.0123 0.0805 0.2047
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0113 0.0731 0.1125
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0078 0.0112
Schistosoma mansoni myst-related protein 0.0017 0.0015 0.0009
Echinococcus multilocularis polyhomeotic proximal chromatin protein 0.0034 0.0142 0.0211
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0026 0.0078 0.0199
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0123 0.0805 0.1242
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0049 0.0248 0.0629
Brugia malayi G-protein coupled receptor 0.0026 0.0078 0.0199
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0026 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0026 0.0078 0.0199
Brugia malayi hypothetical protein 0.0034 0.0142 0.0361
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.048 0.0474
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.048 0.0735
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Brugia malayi Dopamine receptor 0.0026 0.0078 0.0199
Brugia malayi hypothetical protein 0.0025 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Entamoeba histolytica hypothetical protein 0.0029 0.0104 0.5841
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.048 0.1219
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni neuropeptide receptor 0.0026 0.0078 0.0072
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0025 0.0072 0.0102
Brugia malayi GnHR receptor homolog 0.0026 0.0078 0.0199
Schistosoma mansoni neuroglian 0.0018 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Echinococcus granulosus orexin receptor type 2 0.0026 0.0078 0.0112
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0029 0.0104 0.0097
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0292 0.0443
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0026 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0025 0.0071 0.0101
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0361
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0104 0.0097
Echinococcus granulosus allatostatin A receptor 0.0026 0.0078 0.0112
Echinococcus granulosus p2X purinoceptor 4 0.0664 0.4852 0.7529
Loa Loa (eye worm) hypothetical protein 0.0054 0.029 0.0737
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0026 0.0078 0.0112
Onchocerca volvulus 0.008 0.048 0.1219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0168
Loa Loa (eye worm) hypothetical protein 0.0443 0.3196 0.8123
Echinococcus granulosus microtubule associated protein 2 0.045 0.3252 0.5042
Loa Loa (eye worm) hypothetical protein 0.0033 0.0133 0.0337
Loa Loa (eye worm) tyrosinase 1 0.0093 0.0577 0.1467
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0123 0.0805 0.2047
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Toxoplasma gondii histone lysine methyltransferase SET1 0.0039 0.0176 0.3595
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Giardia lamblia Giardia trophozoite antigen GTA-1 0.0034 0.0142 0.7658
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0078 0.0112
Echinococcus granulosus voltage gated potassium channel 0.0022 0.005 0.0067
Schistosoma mansoni P2X receptor subunit 0.0664 0.4852 0.4849
Onchocerca volvulus 0.0026 0.0078 0.0199
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0026 0.0078 0.0199
Echinococcus multilocularis Immunoglobulin 0.0018 0.0021 0.0023
Echinococcus multilocularis L aminoadipate semialdehyde 0.0054 0.029 0.0441
Onchocerca volvulus 0.0123 0.0805 0.2047
Schistosoma mansoni growth hormone secretagogue receptor 0.0026 0.0078 0.0072
Schistosoma mansoni neurotransmitter gated ion channel 0.0025 0.0072 0.0066
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.048 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0054
Brugia malayi PHD-finger family protein 0.0016 0.0006 0.0016
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0054 0.0292 0.0741
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0078 0.0072
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0417 1
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0025 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Onchocerca volvulus 0.0016 0.0006 0.0016
Schistosoma mansoni hypothetical protein 0.0267 0.188 0.1875
Echinococcus granulosus chromobox protein 2 0.0193 0.1332 0.206
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0054 0.0292 0.0741
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.005 0.0067
Schistosoma mansoni hypothetical protein 0.0026 0.0078 0.0072
Onchocerca volvulus 0.0054 0.0292 0.0741
Echinococcus granulosus neuroglian 0.0018 0.0022 0.0025
Onchocerca volvulus 0.0034 0.0142 0.0361
Echinococcus granulosus dna polymerase kappa 0.0019 0.0026 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Schistosoma mansoni sex comb on midleg homolog 0.0363 0.2601 0.2597
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.048 0.0735
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0054 0.0292 0.0741
Loa Loa (eye worm) PHD-finger family protein 0.0016 0.0006 0.0016
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0034 0.0142 0.0136
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0093 0.0577 0.1467
Schistosoma mansoni tyrosine kinase 0.0023 0.0055 0.0049
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.0026 0.0078 0.0072
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.048 1
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0026 0.1465
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0942 0.1453
Plasmodium vivax protein kinase, putative 0.0039 0.0175 0.3571
Onchocerca volvulus 0.0093 0.0577 0.1467
Echinococcus granulosus Immunoglobulin 0.0018 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi Bromodomain associated family protein 0.0016 0.0006 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.0507 0.0501
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni neuropeptide receptor 0.0026 0.0078 0.0072
Echinococcus multilocularis glycine receptor subunit beta 0.0054 0.0292 0.0443
Echinococcus multilocularis nAChR subunit 0.0054 0.0292 0.0443
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Echinococcus multilocularis roundabout 2 0.0037 0.0159 0.0238
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Brugia malayi neuropeptide F receptor 0.0026 0.0078 0.0199
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Echinococcus granulosus peroxidasin 0.0018 0.0022 0.0025
Loa Loa (eye worm) tnks protein 0.0034 0.0142 0.0361
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0026 1
Loa Loa (eye worm) MBCTL1 0.0147 0.0982 0.2497
Echinococcus granulosus g protein coupled receptor 0.0026 0.0078 0.0112
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0018 0.0021 0.0015
Schistosoma mansoni myst-related protein 0.0017 0.0015 0.0009
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0204 0.4891
Echinococcus multilocularis somatostatin receptor 0.0026 0.0078 0.0112
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.048 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Schistosoma mansoni hypothetical protein 0.0026 0.0078 0.0072
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0025 0.0072 0.0183
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.005 0.0067
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0292 0.0741
Schistosoma mansoni P2X receptor subunit 0.0304 0.2158 0.2154
Schistosoma mansoni amine GPCR 0.0026 0.0078 0.0072
Echinococcus multilocularis liprin alpha 2 0.0034 0.0142 0.0211
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0026 0.0078 0.0199
Echinococcus multilocularis nAChR subunit 0.0029 0.0104 0.0151
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Brugia malayi Serotonin receptor 0.0026 0.0078 0.0199
Schistosoma mansoni lip-related protein (liprin) alpha 0.0034 0.0142 0.0136
Echinococcus multilocularis serotonin receptor 0.0026 0.0078 0.0112
Echinococcus multilocularis peroxidasin 0.0018 0.0022 0.0025
Loa Loa (eye worm) CXXC zinc finger family protein 0.0019 0.0024 0.0062
Brugia malayi hypothetical protein 0.0016 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Onchocerca volvulus 0.0025 0.0072 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Schistosoma mansoni SET domain protein 0.0017 0.0009 0.0003
Echinococcus granulosus glycine receptor subunit beta 0.0054 0.0292 0.0443
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi Dopamine receptor protein 1 0.0026 0.0078 0.0199
Onchocerca volvulus 0.0034 0.0142 0.0361
Brugia malayi sulfakinin receptor protein 0.0026 0.0078 0.0199
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0078 0.0112
Onchocerca volvulus 0.0469 0.3391 0.8618
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0078 0.0072
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0054 0.0292 0.0443
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Brugia malayi hypothetical protein 0.0034 0.0142 0.0361
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0029 0.0104 0.0264
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0034 0.0142 0.34
Loa Loa (eye worm) ShTK domain-containing protein 0.0093 0.0577 0.1467
Echinococcus granulosus lysine specific demethylase 5A 0.0092 0.0576 0.0885
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0076 0.0455 0.1155
Loa Loa (eye worm) hypothetical protein 0.0541 0.3935 1
Schistosoma mansoni phd finger protein 0.0051 0.0264 0.0258
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0026 0.0078 0.0112
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0078 0.0112
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0026 0.1465
Brugia malayi CHD4 protein 0.0028 0.0091 0.0231
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Echinococcus multilocularis microtubule associated protein 2 0.045 0.3252 0.5042
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0078 0.0112
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0025 0.0072 0.0102
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Schistosoma mansoni jumonji/arid domain-containing protein 0.0092 0.0576 0.057
Giardia lamblia Kinesin-13 0.0034 0.0142 0.7658
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) mbt repeat family protein 0.0364 0.2608 0.6628
Echinococcus multilocularis p2X purinoceptor 4 0.0664 0.4852 0.7529
Brugia malayi ORL1-like opioid receptor 0.0026 0.0078 0.0199
Echinococcus multilocularis hemicentin 1 0.0018 0.0022 0.0025
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0104 0.0264
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0026 0.0078 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Brugia malayi CXXC zinc finger family protein 0.0019 0.0024 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni nephrin 0.0031 0.0115 0.0108
Onchocerca volvulus 0.0034 0.0142 0.0361
Brugia malayi neuropeptide F receptor 0.0026 0.0078 0.0199
Echinococcus granulosus fmrfamide receptor 0.0026 0.0078 0.0112
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0026 0.0616
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi cask-interacting protein 2 0.0034 0.0142 0.0361
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0078 0.0112
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0034 0.0142 0.0361
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0054
Echinococcus granulosus liprin alpha 2 0.0034 0.0142 0.0211
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0078 0.0199
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0292 0.0443
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0078 0.0112
Schistosoma mansoni hypothetical protein 0.0034 0.0142 0.0136
Schistosoma mansoni P2X receptor subunit 0.0664 0.4852 0.4849
Echinococcus granulosus lachesin 0.0018 0.0022 0.0025
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0071 0.0065
Echinococcus multilocularis chromobox protein 2 0.0193 0.1332 0.206
Echinococcus granulosus Sterile alpha motif SAM 0.0034 0.0142 0.0211
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0026 0.0067
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.008 0.048 0.0735
Brugia malayi Common central domain of tyrosinase family protein 0.0093 0.0577 0.1467
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni vesicular amine transporter 0.0023 0.0059 0.0053
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0054 0.0292 0.0443
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0876 0.6443 1
Echinococcus multilocularis roundabout 2 0.0018 0.0022 0.0025
Onchocerca volvulus 0.0123 0.0805 0.2047
Trypanosoma brucei unspecified product 0.0019 0.0026 0.1465
Echinococcus granulosus p2X purinoceptor 4 0.0664 0.4852 0.7529
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0123 0.0805 0.2047
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0133 0.0337
Plasmodium falciparum amino acid transporter, putative 0.008 0.048 1
Schistosoma mansoni roundabout 0.0018 0.0022 0.0016
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0011 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0078 0.0199
Echinococcus multilocularis tyrosine protein kinase otk 0.0018 0.0022 0.0025
Echinococcus multilocularis tumor suppressor p53 binding protein 1 0.0321 0.2288 0.3545
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.008 0.048 0.1219
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0026 0.0078 0.0112
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0034 0.0142 0.0361
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0072 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0026 0.1465
Brugia malayi PHD-finger family protein 0.0016 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0054 0.029 0.0284
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi hypothetical protein 0.0025 0.0072 0.0183
Echinococcus multilocularis p2X purinoceptor 4 0.0664 0.4852 0.7529
Brugia malayi AKH receptor 0.0026 0.0078 0.0199
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.0078 0.0112
Schistosoma mansoni cpg binding protein 0.0035 0.0146 0.014
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0078 0.0112
Echinococcus granulosus 7TM GPCR rhodopsin 0.0026 0.0078 0.0112
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0292 0.0741
Schistosoma mansoni histamine h1 receptor 0.0026 0.0078 0.0072
Echinococcus granulosus g protein coupled receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0018 0.0022 0.0057
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0018 0.0022 0.0016
Schistosoma mansoni neurotransmitter gated ion channel 0.0025 0.0072 0.0066
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0026 0.0078 0.0112
Onchocerca volvulus 0.0029 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0741
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0018 0.0021 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0026 0.002
Schistosoma mansoni P2X receptor subunit 0.0304 0.2158 0.2154
Schistosoma mansoni Protein aveugle 0.0034 0.0142 0.0136
Schistosoma mansoni opsin-like receptor 0.0026 0.0078 0.0072
Echinococcus granulosus nAChR subunit 0.0054 0.0292 0.0443
Echinococcus multilocularis neuropeptide s receptor 0.0026 0.0078 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0078 0.0072
Brugia malayi Bromodomain containing protein 0.002 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0098 0.0618 0.1569
Echinococcus granulosus Sterile alpha motif type 0.0034 0.0142 0.0211
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Onchocerca volvulus Tyrosine kinase homolog 0.0017 0.0011 0.0027
Schistosoma mansoni septate junction protein 0.0018 0.0022 0.0016
Echinococcus multilocularis polycomb protein SCMH1 0.0363 0.2601 0.4032
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0104 0.0097
Schistosoma mansoni opsin-like receptor 0.0026 0.0078 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0022 0.0057
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0026 0.0031
Schistosoma mansoni cpg binding protein 0.0035 0.0146 0.014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0248 0.0629
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0078 0.0112
Echinococcus granulosus G protein coupled receptor 139 0.0026 0.0078 0.0112
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0054 0.0292 0.0443
Echinococcus multilocularis orexin receptor type 2 0.0026 0.0078 0.0112
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0054 0.0292 0.0443
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0972 0.0966
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0057
Onchocerca volvulus 0.0026 0.0078 0.0199
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0292 0.0741
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0078 0.0112
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0264
Onchocerca volvulus 0.0026 0.0078 0.0199
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.0078 0.0072
Schistosoma mansoni nAChR subunit 0.0054 0.0292 0.0285
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0028 0.0091 0.0131
Brugia malayi PHD-finger family protein 0.0016 0.0006 0.0016
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0018 0.0022 0.0057
Echinococcus multilocularis neuropeptide receptor A26 0.0026 0.0078 0.0112
Echinococcus multilocularis histone acetyltransferase MYST2 0.0147 0.0982 0.1517
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Brugia malayi jmjC domain containing protein 0.0136 0.0899 0.2283
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0054
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0026 0.002
Echinococcus multilocularis allatostatin A receptor 0.0026 0.0078 0.0112
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0026 0.0078 0.0072
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0292 0.0285
Schistosoma mansoni opsin-like receptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0199
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0054
Brugia malayi hypothetical protein 0.0026 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0183
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0836
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0021 0.0054
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.005 0.0067
Plasmodium vivax hypothetical protein, conserved 0.008 0.048 1
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0054 0.0292 0.0443
Onchocerca volvulus 0.0034 0.0142 0.0361
Schistosoma mansoni cpg binding protein 0.0019 0.0024 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0139
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0034 0.0142 0.0211
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0026 0.0031
Schistosoma mansoni acetylcholine receptor-related 0.0025 0.0072 0.0066
Brugia malayi coiled-coil like protein 1 0.0034 0.0142 0.0361
Echinococcus multilocularis cpg binding protein 0.0035 0.0146 0.0218
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.048 0.0735
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0054
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0292 0.0443
Brugia malayi hypothetical protein 0.0016 0.0006 0.0016
Onchocerca volvulus 0.0016 0.0006 0.0016
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0026 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.008 0.048 0.1219
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0541 0.3935 1
Brugia malayi putative neuropeptide receptor 0.0026 0.0078 0.0199
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.048 0.0474
Brugia malayi putative neuropeptide receptor NPR1 0.0026 0.0078 0.0199
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.048 0.0735
Brugia malayi follicle stimulating hormone receptor 0.0026 0.0078 0.0199

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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