Detailed information for compound 91713

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 281.23 | Formula: C12H7N7O2
  • H donors: 1 H acceptors: 4 LogP: 0.91 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1cccc(c1)n1nnc2n(c1=O)cnc2C(=O)N
  • InChi: 1S/C12H7N7O2/c13-5-7-2-1-3-8(4-7)19-12(21)18-6-15-9(10(14)20)11(18)16-17-19/h1-4,6H,(H2,14,20)
  • InChiKey: SUNHRZWSLLLZKU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0135 0.1335 0.1346
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Onchocerca volvulus 0.0042 0.0229 0.0842
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0847 0.9725 1
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0261 0.2812 0.2812
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0026 0.0048 0.0049
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus multilocularis glutamate receptor 2 0.013 0.127 0.127
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0261 0.2812 0.2877
Schistosoma mansoni opsin-like receptor 0.0073 0.0602 0.0599
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Schistosoma mansoni neuropeptide F-like receptor 0.0073 0.0602 0.0599
Schistosoma mansoni hypothetical protein 0.0073 0.0602 0.0599
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0073 0.0602 0.0619
Brugia malayi Serotonin receptor 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0599 0.0616
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0073 0.0602 0.0599
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0075 0.0629 0.0617
Echinococcus granulosus cyclin dependent kinase 1 0.0026 0.005 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0205 0.2152 0.2152
Trypanosoma cruzi Vacuolar proton pyrophosphatase 1, putative 0.0265 0.2859 0.2925
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus cyclin dependent kinase 5 0.0026 0.005 0.0052
Schistosoma mansoni neuropeptide F-like receptor 0.0073 0.0602 0.0599
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Echinococcus multilocularis purine nucleoside phosphorylase 0.0092 0.0824 0.0824
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0179 0.1854 0.1881
Echinococcus multilocularis tyrosine protein kinase Blk 0.003 0.0094 0.0094
Echinococcus multilocularis neuropeptides capa receptor 0.0073 0.0602 0.0602
Echinococcus granulosus 5'partial|biotin protein ligase 0.0027 0.0056 0.0058
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0023 0.0011 0.0011
Giardia lamblia Kinase, CMGC CDK 0.0026 0.005 0.002
Trypanosoma cruzi vacuolar-type proton translocating pyrophosphatase 1 0.0265 0.2859 0.2925
Leishmania major extracellular receptor, putative 0.0026 0.0048 0.0028
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0092 0.0824 0.0818
Loa Loa (eye worm) hypothetical protein 0.0049 0.0322 0.0331
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0049 0.0322 0.03
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0025 0.0031 0.0011
Echinococcus multilocularis hexokinase 0.0209 0.2198 0.2198
Giardia lamblia Hypothetical protein 0.0038 0.0186 0.016
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0023 0.0011 0.0011
Brugia malayi Receptor family ligand binding region containing protein 0.0031 0.011 0.0092
Loa Loa (eye worm) hypothetical protein 0.0025 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0038 0.0192 0.0166
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0092 0.0824 0.2879
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0826 0.0849
Entamoeba histolytica serine/threonine protein kinase, putative 0.0056 0.0402 0.1428
Echinococcus granulosus N terminal of biotin protein ligase 0.0052 0.0348 0.0358
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0205 0.2152 0.2152
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0075 0.0622 0.0639
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0092 0.0824 0.361
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0038 0.0192 0.0177
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0409 0.039
Brugia malayi G protein-coupled receptor F59B2.13 0.0073 0.0602 0.0599
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0025 0.0031 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Chlamydia trachomatis hypothetical protein 0.0052 0.0348 0.1175
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0199 0.2087 0.7421
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0038 0.0192 0.0197
Brugia malayi amidase 0.0198 0.2072 0.2114
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0075 0.0629 0.0617
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0826 0.083
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0095 0.0862 0.3065
Echinococcus multilocularis hexokinase 0.0209 0.2198 0.2198
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0026 0.005 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0076 0.0047
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0056 0.0402 0.0402
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0075 0.0622 0.0622
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.0311
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0073 0.0602 0.0602
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0058 0.042 0.0788
Plasmodium falciparum hexokinase 0.0209 0.2198 0.2244
Echinococcus multilocularis g protein coupled receptor 0.0073 0.0602 0.0602
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0025 0.0031 0.0011
Schistosoma mansoni fatty-acid amide hydrolase 0.0198 0.2072 0.2114
Echinococcus multilocularis purine nucleoside phosphorylase 0.0092 0.0824 0.0824
Entamoeba histolytica cell division protein kinase 2, putative 0.0026 0.005 0.0179
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.0602 0.0599
Schistosoma mansoni tyrosine kinase 0.0128 0.1251 0.1268
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0073 0.0602 0.0602
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.03
Loa Loa (eye worm) hexokinase 0.0065 0.05 0.0514
Echinococcus multilocularis neuropeptides capa receptor 0.0073 0.0602 0.0602
Echinococcus granulosus receptor type guanylyl cyclase 0.0031 0.011 0.0113
Plasmodium vivax aspartyl protease, putative 0.0042 0.0229 0.0215
Onchocerca volvulus 0.0086 0.0751 0.3269
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0073 0.0602 0.0599
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0026 0.005 0.0052
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0236 0.2524 0.258
Echinococcus multilocularis cyclin dependent kinase 0.0026 0.005 0.005
Schistosoma mansoni hexokinase 0.0209 0.2198 0.2244
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0236 0.2524 0.2572
Echinococcus multilocularis fmrfamide receptor 0.0073 0.0602 0.0602
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0048 0.0028
Loa Loa (eye worm) hypothetical protein 0.0042 0.0229 0.0235
Echinococcus multilocularis nmda type glutamate receptor 0.0208 0.2196 0.2196
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.0311
Plasmodium vivax plasmepsin IV, putative 0.0176 0.1811 0.1845
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0135 0.1335 0.1346
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0261 0.2812 0.2877
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0073 0.0602 0.0602
Brugia malayi GnHR receptor homolog 0.0073 0.0602 0.0599
Onchocerca volvulus 0.0073 0.0602 0.2577
Brugia malayi Glutamate receptor 2 precursor 0.0179 0.1844 0.1879
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0025 0.0031 0.0011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0205 0.2152 0.2152
Brugia malayi neuropeptide F receptor 0.0073 0.0602 0.0599
Plasmodium vivax vacuolar-type H+ pumping pyrophosphatase, putative 0.0265 0.2859 0.2925
Echinococcus granulosus serotonin receptor 0.0073 0.0602 0.0619
Schistosoma mansoni myosin xvIII 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0261 0.2812 1
Echinococcus granulosus protein kinase shaggy 0.0057 0.0409 0.042
Loa Loa (eye worm) biotin protein ligase 1 0.0038 0.0186 0.0191
Onchocerca volvulus 0.0065 0.0511 0.2153
Giardia lamblia Kinase, PLK 0.0056 0.0402 0.0383
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0847 0.9725 1
Plasmodium falciparum plasmepsin IV 0.0176 0.1811 0.1845
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0031 0.011 0.0289
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0262 0.2833 0.2898
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0048 0.0028
Onchocerca volvulus 0.0114 0.1085 0.4825
Loa Loa (eye worm) hexokinase 0.0209 0.2198 0.2261
Echinococcus multilocularis synaptic glycoprotein sc2 0.0049 0.0322 0.0322
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0073 0.0602 0.0602
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0049 0.0322 0.1144
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0076 0.0047
Brugia malayi Polyprenyl synthetase family protein 0.0847 0.9725 1
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0322 0.03
Echinococcus granulosus tyrosine kinase 0.003 0.0094 0.0097
Loa Loa (eye worm) hypothetical protein 0.0114 0.1085 0.1116
Brugia malayi neuropeptide F receptor 0.0073 0.0602 0.0599
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0179 0.1854 0.1881
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0092 0.0824 0.0828
Brugia malayi Dopamine receptor protein 2 0.0073 0.0602 0.0599
Echinococcus multilocularis purine nucleoside phosphorylase 0.0092 0.0824 0.0824
Plasmodium vivax aspartyl protease, putative 0.0042 0.0229 0.0215
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 2, putative 0.0265 0.2859 0.2925
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0826 0.0849
Loa Loa (eye worm) glutamate receptor 0.0026 0.0048 0.0049
Echinococcus multilocularis hexokinase type 2 0.0209 0.2198 0.2198
Entamoeba histolytica hypothetical protein 0.0026 0.0048 0.0169
Echinococcus multilocularis somatostatin receptor 0.0073 0.0602 0.0602
Brugia malayi Dopamine receptor protein 1 0.0073 0.0602 0.0599
Loa Loa (eye worm) aspartyl protease 6 0.0042 0.0229 0.0235
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Plasmodium falciparum polyprenol reductase, putative 0.0049 0.0322 0.0311
Echinococcus multilocularis tyrosine kinase 0.0031 0.011 0.011
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0176 0.1811 0.1862
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0135 0.1335 0.4748
Trypanosoma cruzi Biotin--acetyl-CoA-carboxylase ligase, putative 0.0038 0.0186 0.0171
Loa Loa (eye worm) SRC-1 0.0032 0.0119 0.0123
Trypanosoma cruzi polo-like protein kinase, putative 0.0056 0.0402 0.0393
Echinococcus granulosus fatty acid amide hydrolase 1 0.0198 0.2072 0.213
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0176 0.1811 0.1836
Plasmodium vivax biotin--[acetyl-CoA-carboxylase] synthetase, putative 0.0038 0.0186 0.0171
Entamoeba histolytica PH domain containing protein kinase, putative 0.0025 0.0031 0.0109
Schistosoma mansoni amine GPCR 0.0073 0.0602 0.0599
Wolbachia endosymbiont of Brugia malayi biotin-(acetyl-CoA carboxylase) ligase 0.0038 0.0186 0.0594
Echinococcus multilocularis sphingosine 1 phosphate lyase 1 0.0074 0.0615 0.0615
Trypanosoma brucei hexokinase 0.0209 0.2198 0.2244
Trypanosoma brucei Biotin--acetyl-CoA-carboxylase ligase, putative 0.0038 0.0186 0.0171
Schistosoma mansoni glutamate receptor AMPA 0.0179 0.1844 0.1879
Schistosoma mansoni glutamate receptor AMPA 0.0179 0.1844 0.1879
Trypanosoma brucei cdc2-related kinase 1 0.0026 0.005 0.0031
Trypanosoma cruzi hexokinase, putative 0.0209 0.2198 0.2244
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0847 0.9725 1
Onchocerca volvulus Tyrosine kinase homolog 0.0087 0.0759 0.331
Brugia malayi biotin--acetyl-CoA-carboxylase ligase family protein 0.0038 0.0186 0.0171
Entamoeba histolytica biotin--acetyl-CoA-carboxylase ligase, putative 0.0038 0.0186 0.0661
Echinococcus granulosus biogenic amine 5HT receptor 0.0073 0.0602 0.0619
Mycobacterium ulcerans hypothetical protein 0.0135 0.1335 0.1355
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Loa Loa (eye worm) G-protein coupled receptor 0.0073 0.0602 0.0619
Trypanosoma cruzi sphingosine 1-phosphate lyase, putative 0.0074 0.0615 0.0613
Brugia malayi Immunoglobulin I-set domain containing protein 0.0101 0.0933 0.0941
Entamoeba histolytica cell division protein kinase 2, putative 0.0026 0.005 0.0179
Onchocerca volvulus 0.0031 0.011 0.0289
Plasmodium falciparum plasmepsin VI 0.0176 0.1811 0.1845
Loa Loa (eye worm) amidase 0.0024 0.002 0.0021
Trypanosoma brucei hexokinase, putative 0.0209 0.2198 0.2244
Entamoeba histolytica hypothetical protein 0.0049 0.0322 0.1144
Echinococcus multilocularis purine nucleoside phosphorylase 0.0092 0.0824 0.0824
Mycobacterium ulcerans hypothetical protein 0.0049 0.0322 0.0311
Trypanosoma cruzi polo-like protein kinase, putative 0.0056 0.0402 0.0393
Schistosoma mansoni glutamate receptor NMDA 0.0338 0.372 0.3812
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0075 0.0622 0.0639
Echinococcus multilocularis g protein coupled receptor 0.0073 0.0602 0.0602
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0261 0.2812 0.2877
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0038 0.0192 0.0197
Trypanosoma brucei sphingosine 1-phosphate lyase, putative 0.0074 0.0615 0.0613
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0261 0.2812 1
Echinococcus multilocularis fmrfamide receptor 0.0073 0.0602 0.0602
Echinococcus granulosus tyrosine protein kinase Blk 0.003 0.0094 0.0097
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0049 0.0322 0.03
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0073 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Leishmania major protein kinase A catalytic subunit isoform 1 0.0025 0.0031 0.0011
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0026 0.005 0.0031
Trypanosoma cruzi sphingosine 1-phosphate lyase, putative 0.0074 0.0615 0.0613
Schistosoma mansoni opsin-like receptor 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.005 0.0031
Schistosoma mansoni growth hormone secretagogue receptor 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Leishmania major solanesyl-diphosphate synthase, putative 0.0261 0.2812 0.2877
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0336 0.3702 0.3702
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0058 0.042 0.0788
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0176 0.1811 0.1811
Loa Loa (eye worm) hypothetical protein 0.0065 0.0511 0.0525
Mycobacterium tuberculosis Possible lysophospholipase 0.0135 0.1335 0.1355
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.03
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0176 0.1811 0.1836
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0261 0.2812 0.2877
Onchocerca volvulus 0.0073 0.0602 0.2577
Onchocerca volvulus 0.0114 0.1085 0.4825
Onchocerca volvulus 0.0114 0.1085 0.4825
Echinococcus granulosus atrial natriuretic peptide receptor 0.0026 0.0048 0.0049
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0142 0.1417 0.143
Onchocerca volvulus 0.0073 0.0602 0.2577
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0454 0.509 0.5233
Echinococcus multilocularis cyclin dependent kinase 1 0.0026 0.005 0.005
Brugia malayi hypothetical protein 0.0042 0.0229 0.0215
Echinococcus granulosus tyrosine protein kinase Src42A 0.0025 0.0032 0.0033
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Plasmodium falciparum plasmepsin IX 0.0042 0.0229 0.0215
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Onchocerca volvulus 0.0073 0.0602 0.2577
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0114 0.1085 0.1116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Onchocerca volvulus 0.0209 0.2198 1
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0038 0.0192 0.0682
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0119 0.0123
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus nmda type glutamate receptor 0.0208 0.2196 0.2258
Echinococcus granulosus nmda type glutamate receptor 0.0102 0.0941 0.0968
Schistosoma mansoni biogenic amine receptor 0.0073 0.0602 0.0599
Echinococcus granulosus neuropeptides capa receptor 0.0073 0.0602 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Entamoeba histolytica hypothetical protein 0.0199 0.2087 0.7421
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0236 0.2524 0.2572
Onchocerca volvulus 0.0084 0.0731 0.3176
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0847 0.9725 0.9725
Echinococcus granulosus g protein coupled receptor 0.0073 0.0602 0.0619
Schistosoma mansoni biogenic amine (5HT) receptor 0.0073 0.0602 0.0599
Echinococcus granulosus tyrosine kinase 0.0031 0.011 0.0113
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Loa Loa (eye worm) hexokinase 0.0131 0.1282 0.1318
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0847 0.9725 1
Trypanosoma cruzi cdc2-related kinase 1 0.0026 0.005 0.0031
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus rho-associated protein kinase 1 0.0086 0.0751 0.0772
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0119 0.0119
Echinococcus granulosus hexokinase 0.0209 0.2198 0.2261
Echinococcus granulosus hexokinase type 2 0.0209 0.2198 0.2261
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni amidase 0.0198 0.2072 0.2114
Echinococcus multilocularis hexokinase 0.0209 0.2198 0.2198
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0025 0.0032 0.0032
Echinococcus granulosus c-Jun N-terminal kinases 0.0135 0.1329 0.1367
Trypanosoma brucei protein kinase, putative 0.0057 0.0409 0.04
Plasmodium falciparum plasmepsin I 0.0176 0.1811 0.1845
Brugia malayi sulfakinin receptor protein 0.0073 0.0602 0.0599
Schistosoma mansoni kinase 0.0029 0.0084 0.0066
Trypanosoma cruzi hexokinase, putative 0.0209 0.2198 0.2244
Onchocerca volvulus 0.0057 0.0409 0.1679
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.005 0.002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0073 0.0602 0.0619
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0132 0.1299 0.1318
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0135 0.1335 0.471
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0075 0.0629 0.0627
Entamoeba histolytica hypothetical protein, conserved 0.0025 0.0031 0.011
Brugia malayi protein-tyrosine kinase 0.003 0.0094 0.0076
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0038 0.0192 0.0177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Loa Loa (eye worm) hypothetical protein 0.0049 0.0322 0.0331
Trypanosoma cruzi UDP-glucoronosyl and UDP-glucosyl transferase, putative 0.0125 0.1209 0.1225
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0065 0.0511 0.0525
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0026 0.005 0.0052
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Loa Loa (eye worm) neuropeptide F receptor 0.0073 0.0602 0.0619
Echinococcus granulosus fatty acid amide hydrolase 1 0.0024 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0038 0.0192 0.0166
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0057 0.0409 0.04
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0073 0.0602 0.0619
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0847 0.9725 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0205 0.2152 0.2213
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0073 0.0602 0.0599
Giardia lamblia Kinase, CMGC CDK 0.0026 0.005 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.005 0.0031
Echinococcus granulosus orexin receptor type 2 0.0073 0.0602 0.0619
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0409 0.1453
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0026 0.005 0.0052
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0132 0.1299 0.1299
Brugia malayi hexokinase 0.0209 0.2198 0.2244
Loa Loa (eye worm) neuropeptide F receptor 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0075 0.0622 0.0622
Entamoeba histolytica PH domain containing protein kinase, putative 0.0025 0.0031 0.0109
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0025 0.0031 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0032 0.0119 0.0123
Leishmania major biotin/lipoate protein ligase-like protein 0.0038 0.0186 0.0171
Schistosoma mansoni hypothetical protein 0.0075 0.0622 0.062
Echinococcus granulosus synaptic glycoprotein sc2 0.0049 0.0322 0.0331
Entamoeba histolytica hexokinase 1 0.0209 0.2198 0.7818
Echinococcus granulosus hexokinase 0.0209 0.2198 0.2261
Loa Loa (eye worm) glutamate receptor 1 0.0179 0.1844 0.1896
Echinococcus multilocularis serotonin receptor 0.0073 0.0602 0.0602
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Onchocerca volvulus 0.0042 0.0229 0.0842
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0261 0.2812 0.2877
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0847 0.9725 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0511 0.0525
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0236 0.2524 0.8975
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0236 0.2524 0.258
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0024 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase Lyn 0.0034 0.0139 0.0143
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0049 0.0322 0.03
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0119 0.0119
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0261 0.2812 0.2812
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0073 0.0602 0.0619
Brugia malayi Eukaryotic aspartyl protease family protein 0.0042 0.0229 0.0215
Schistosoma mansoni neuropeptide f receptor 76f 0.0073 0.0602 0.0599
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0826 0.0826
Brugia malayi Protein kinase domain containing protein 0.0026 0.005 0.0031
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0236 0.2524 0.258
Entamoeba histolytica hexokinase 2 0.0209 0.2198 0.7818
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0073 0.0602 0.0602
Schistosoma mansoni alpha-1 adrenergic receptor 0.0073 0.0602 0.0599
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Echinococcus granulosus glutamate receptor subunit protein glur 0.0075 0.0622 0.0639
Echinococcus multilocularis dro:myosuppressin receptor 0.0073 0.0602 0.0602
Onchocerca volvulus Serine\/threonine kinase homolog 0.0056 0.0402 0.1646
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.0602 0.0619
Echinococcus multilocularis g protein coupled receptor 0.0073 0.0602 0.0602
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Schistosoma mansoni amine GPCR 0.0073 0.0602 0.0599
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.01 0.0917 0.0924
Loa Loa (eye worm) hypothetical protein 0.0074 0.0615 0.0632
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0454 0.509 0.5233
Loa Loa (eye worm) hypothetical protein 0.0262 0.2833 0.2913
Leishmania major protein kinase A catalytic subunit 0.0025 0.0031 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0261 0.2812 1
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0114 0.1085 0.1097
Schistosoma mansoni biogenic amine receptor 0.0073 0.0602 0.0599
Plasmodium vivax aspartyl proteinase, putative 0.0176 0.1811 0.1845
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0073 0.0602 0.0599
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0135 0.1335 0.1346
Brugia malayi Hexokinase family protein 0.0131 0.1282 0.13
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Echinococcus granulosus peptide allatostatin:somatostatin 0.0073 0.0602 0.0619
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0049 0.0322 0.0311
Plasmodium vivax hexokinase, putative 0.0209 0.2198 0.2244
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0026 0.0048 0.0048
Plasmodium falciparum lysophospholipase, putative 0.0135 0.1335 0.1355
Onchocerca volvulus 0.0114 0.1085 0.4825
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0075 0.0629 0.0627
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0073 0.0602 0.0619
Brugia malayi Dopamine receptor 0.0073 0.0602 0.0599
Brugia malayi follicle stimulating hormone receptor 0.0073 0.0602 0.0599
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Echinococcus multilocularis cyclin dependent kinase 1 0.0026 0.005 0.005
Trypanosoma cruzi monoglyceride lipase, putative 0.0135 0.1335 0.1355
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Trypanosoma cruzi Biotin--acetyl-CoA-carboxylase ligase, putative 0.0038 0.0186 0.0171
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.0311
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0049 0.0322 0.0311
Brugia malayi cell division control protein 2 homolog 0.0026 0.005 0.0031
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0038 0.0192 0.0166
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0058
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0114 0.1085 0.1097
Schistosoma mansoni sphingosine phosphate lyase 0.0074 0.0615 0.0613
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Leishmania major polyprenyl synthase, putative 0.0454 0.509 0.5223
Loa Loa (eye worm) RGC/RGC protein kinase 0.0031 0.011 0.0113
Onchocerca volvulus 0.0114 0.1085 0.4825
Schistosoma mansoni adenoreceptor 0.0073 0.0602 0.0599
Echinococcus granulosus glutamate receptor 2 0.0205 0.2152 0.2213
Echinococcus multilocularis Zinc finger, PHD finger 0.0038 0.0192 0.0192
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Schistosoma mansoni trans-prenyltransferase 0.0261 0.2812 0.2877
Echinococcus granulosus alpha 1A adrenergic receptor 0.0073 0.0602 0.0619
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 1 0.0265 0.2859 0.2925
Loa Loa (eye worm) RGC/RGC protein kinase 0.0031 0.011 0.0113
Brugia malayi Protein kinase domain containing protein 0.0263 0.2845 0.291
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0261 0.2812 0.2877
Onchocerca volvulus Neuropeptide F receptor homolog 0.0073 0.0602 0.2577
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0026 0.0048 0.0028
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0073 0.0602 0.0602
Echinococcus granulosus neuropeptide s receptor 0.0073 0.0602 0.0619
Onchocerca volvulus 0.0209 0.2198 1
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0038 0.0192 0.0682
Loa Loa (eye worm) hypothetical protein 0.0049 0.0313 0.0322
Echinococcus granulosus neuropeptide Y receptor 0.0073 0.0602 0.0619
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0092 0.0824 0.0828
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0092 0.0824 0.0828
Loa Loa (eye worm) hypothetical protein 0.0049 0.0313 0.0322
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0454 0.509 0.509
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Echinococcus granulosus dro:myosuppressin receptor 0.0073 0.0602 0.0619
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0135 0.1329 0.1367
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0075 0.0629 0.2236
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0065 0.0511 0.0525
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0058
Onchocerca volvulus 0.0073 0.0602 0.2577
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0205 0.2152 0.2152
Onchocerca volvulus 0.0209 0.2198 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0075 0.0629 0.0617
Loa Loa (eye worm) phosphatidylinositol 3 0.0067 0.0526 0.0541
Trypanosoma cruzi polyprenyl synthase, putative 0.0454 0.509 0.5223
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0032 0.0119 0.0119
Echinococcus multilocularis biotin protein ligase 0.0038 0.0186 0.0186
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0056 0.0402 0.0413
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Schistosoma mansoni glutamate receptor kainate 0.0179 0.1844 0.1879
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Plasmodium falciparum protein kinase 5 0.0026 0.005 0.0031
Trypanosoma brucei hexokinase 0.0209 0.2198 0.2244
Echinococcus multilocularis hormone sensitive lipase 0.0262 0.2833 0.2833
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0049 0.0322 0.0311
Brugia malayi G protein-coupled receptor 0.0073 0.0602 0.0599
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0073 0.0602 0.0602
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0049 0.0322 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.1335 0.1346
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Schistosoma mansoni amine GPCR 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus sphingosine 1 phosphate lyase 1 0.0074 0.0615 0.0632
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0205 0.2152 0.2213
Schistosoma mansoni glutamate receptor kainate 0.0179 0.1844 0.1879
Brugia malayi Hexokinase family protein 0.0065 0.05 0.0494
Echinococcus granulosus tyrosine protein kinase Src64B 0.0032 0.0119 0.0123
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0049 0.0322 0.1144
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0026 0.0048 0.0048
Plasmodium falciparum plasmepsin II 0.0176 0.1811 0.1845
Entamoeba histolytica hypothetical protein, conserved 0.0025 0.0031 0.011
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Mycobacterium ulcerans bifunctional protein BirA 0.0162 0.1643 0.1673
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0261 0.2812 1
Echinococcus granulosus metabotropic glutamate receptor 5 0.0026 0.0048 0.0049
Echinococcus granulosus cyclin dependent kinase 0.0026 0.005 0.0052
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Toxoplasma gondii aspartyl protease ASP3 0.0042 0.0229 0.0204
Echinococcus multilocularis nmda type glutamate receptor 0.0102 0.0941 0.0941
Echinococcus multilocularis tyrosine protein kinase Srms 0.003 0.0094 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.1329 0.1349
Brugia malayi putative neuropeptide receptor NPR1 0.0073 0.0602 0.0599
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0409 0.042
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Plasmodium falciparum lysophospholipase, putative 0.0135 0.1335 0.1355
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis cyclin dependent kinase 5 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0058 0.042 0.1431
Plasmodium falciparum esterase, putative 0.0135 0.1335 0.1355
Onchocerca volvulus 0.0131 0.1282 0.5739
Echinococcus granulosus fatty acid amide hydrolase 1 0.0198 0.2072 0.213
Plasmodium falciparum biotin protein ligase, putative 0.0038 0.0186 0.0171
Schistosoma mansoni protein kinase 0.0031 0.011 0.0092
Brugia malayi Synaptic glycoprotein SC2 0.0049 0.0322 0.0311
Echinococcus multilocularis sex peptide receptor 0.0073 0.0602 0.0602
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0073 0.0602 0.0602
Schistosoma mansoni purine nucleoside phosphorylase 0.0092 0.0824 0.0828
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0073 0.0602 0.0619
Echinococcus granulosus biogenic amine 5HT receptor 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Echinococcus multilocularis protein kinase shaggy 0.0057 0.0409 0.0409
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0025 0.0031 0.0011
Onchocerca volvulus 0.0114 0.1085 0.4825
Echinococcus granulosus hormone sensitive lipase 0.0262 0.2833 0.2913
Echinococcus granulosus glutamate NMDA receptor subunit 0.0338 0.372 0.3825
Echinococcus granulosus 7tm_1 domain containing protein 0.0073 0.0602 0.0619
Schistosoma mansoni glutamate receptor kainate 0.0179 0.1844 0.1879
Brugia malayi Polyprenyl synthetase family protein 0.0261 0.2812 0.2877
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.1335 0.1346
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0026 0.0048 0.0049
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Echinococcus multilocularis neuropeptide receptor 0.0073 0.0602 0.0602
Loa Loa (eye worm) hexokinase type II 0.0209 0.2198 0.2261
Plasmodium falciparum lysophospholipase, putative 0.0135 0.1335 0.1355
Toxoplasma gondii aspartyl protease 0.0042 0.0229 0.0204
Echinococcus granulosus somatostatin receptor 0.0073 0.0602 0.0619
Plasmodium falciparum V-type H(+)-translocating pyrophosphatase, putative 0.0265 0.2859 0.2925
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0049 0.0322 0.0311
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0847 0.9725 1
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.03
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Schistosoma mansoni biotin-protein ligase 0.0038 0.0186 0.0171
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0826 0.0826
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0338 0.372 0.372
Echinococcus multilocularis g-protein coupled receptor 0.0073 0.0602 0.0602
Loa Loa (eye worm) TK protein kinase 0.003 0.0094 0.0097
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0038 0.0192 0.0177
Onchocerca volvulus 0.0114 0.1085 0.4825
Leishmania major vacuolar-type proton translocating pyrophosphatase 1, putative 0.0265 0.2859 0.2925
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0261 0.2812 0.2877
Echinococcus multilocularis neuropeptide receptor A26 0.0073 0.0602 0.0602
Echinococcus multilocularis NMDA receptor 0.0075 0.0622 0.0622
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0262 0.2833 0.2898
Toxoplasma gondii V-type H(+)-translocating pyrophosphatase VP1 0.0265 0.2859 0.2917
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Plasmodium falciparum plasmepsin V 0.0042 0.0229 0.0215
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0205 0.2152 0.2213
Echinococcus granulosus neuropeptides capa receptor 0.0073 0.0602 0.0619
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0073 0.0602 0.0599
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Echinococcus multilocularis purine nucleoside phosphorylase 0.0073 0.0599 0.0599
Echinococcus multilocularis G protein coupled receptor 139 0.0073 0.0602 0.0602
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0049 0.0322 0.1144
Loa Loa (eye worm) hypothetical protein 0.0198 0.2072 0.213
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0032 0.0119 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0402 0.0393
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0409 0.039
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0075 0.0622 0.0622
Brugia malayi G-protein coupled receptor 0.0073 0.0602 0.0599
Brugia malayi Receptor family ligand binding region containing protein 0.0026 0.0048 0.0028
Echinococcus multilocularis N terminal of biotin protein ligase 0.0052 0.0348 0.0348
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Schistosoma mansoni tyrosine kinase 0.0136 0.1345 0.1365
Schistosoma mansoni tyrosine kinase 0.0032 0.0119 0.0102
Brugia malayi Hexokinase family protein 0.0209 0.2198 0.2244
Loa Loa (eye worm) hypothetical protein 0.0176 0.1811 0.1862
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0075 0.0629 0.0627
Brugia malayi Stress-activated protein kinase jnk-1 0.0135 0.1329 0.1349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Plasmodium vivax aspartyl protease, putative 0.0042 0.0229 0.0215
Echinococcus granulosus tyrosine protein kinase shark 0.0136 0.1345 0.1383
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0336 0.3702 0.3806
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0038 0.0192 0.0166
Schistosoma mansoni tyrosine kinase 0.0032 0.0119 0.0102
Loa Loa (eye worm) hypothetical protein 0.0125 0.1209 0.1243
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0409 0.039
Schistosoma mansoni neuropeptide receptor 0.0073 0.0602 0.0599
Onchocerca volvulus 0.0073 0.0602 0.2577
Schistosoma mansoni hypothetical protein 0.0073 0.0602 0.0599
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Entamoeba histolytica protein kinase, putative 0.0057 0.0409 0.1453
Brugia malayi Melatonin receptor type 1A 0.0073 0.0602 0.0599
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0261 0.2812 0.2877
Brugia malayi larval opioid receptor 0.0073 0.0602 0.0599
Echinococcus granulosus allatostatin A receptor 0.0073 0.0602 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0032 0.0119 0.0119
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0073 0.0602 0.0599
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0336 0.3702 0.3793
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Brugia malayi RE15519p 0.0073 0.0602 0.0599
Plasmodium falciparum plasmepsin VII 0.0042 0.0229 0.0215
Trypanosoma cruzi cdc2-related kinase 1 0.0026 0.005 0.0031
Onchocerca volvulus 0.0049 0.0322 0.1274
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0032 0.0119 0.0123
Plasmodium falciparum biotin--acetyl-CoA-carboxylase, putative 0.0038 0.0186 0.0171
Plasmodium falciparum plasmepsin III 0.0042 0.0229 0.0215
Echinococcus granulosus hypothetical protein 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0049 0.0313 0.0322
Treponema pallidum biotin--acetyl-CoA-carboxylase ligase 0.0173 0.1773 0.3458
Loa Loa (eye worm) melatonin receptor type 1A 0.0073 0.0602 0.0619
Brugia malayi Tachykinin-like peptides receptor 99D 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0132 0.1299 0.1336
Loa Loa (eye worm) RGC/RGC protein kinase 0.0031 0.011 0.0113
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0025 0.0031 0.0011
Echinococcus granulosus neuropeptide Y receptor 0.0073 0.0602 0.0619
Chlamydia trachomatis biotin synthetase 0.0038 0.0186 0.0594
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0032 0.0119 0.0119
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0026 0.0048 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0031 0.0011
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0075 0.0629 0.2236
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Plasmodium vivax protein kinase Crk2 0.0026 0.005 0.0031
Schistosoma mansoni neuropeptide receptor 0.0073 0.0602 0.0599
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0409 0.1453
Echinococcus granulosus sex peptide receptor 0.0073 0.0602 0.0619
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Echinococcus multilocularis glutamate receptor 2 0.0205 0.2152 0.2152
Trypanosoma brucei cdc2-related kinase 3 0.0026 0.005 0.0031
Leishmania major sphingosine 1-phosphate lyase 0.0074 0.0615 0.0613
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus multilocularis rho associated protein kinase 0.0086 0.0751 0.0751
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0025 0.0031 0.0011
Brugia malayi hypothetical protein 0.0049 0.0313 0.0302
Brugia malayi hexokinase type II 0.0066 0.0521 0.0516
Echinococcus granulosus hexokinase 0.0209 0.2198 0.2261
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0602 0.0619
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0046 0.0279 0.0256
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0409 0.039
Leishmania major protein kinase A catalytic subunit isoform 2 0.0025 0.0031 0.0011
Brugia malayi intracellular kinase 0.0057 0.0409 0.04
Loa Loa (eye worm) hypothetical protein 0.0065 0.0511 0.0525
Mycobacterium leprae POSSIBLE BIFUNCTIONAL PROTEIN BirA: BIOTIN OPERON REPRESSOR + BIOTIN--[ACETYL-COA-CARBOXYLASE] SYNTHETASE (BIOTIN--PROTEIN LIGAS 0.0027 0.0056 0.0129
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0075 0.0622 0.0639
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0092 0.0824 0.0818
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.003 0.0094 0.0097
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0073 0.0602 0.0599
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0073 0.0602 0.0619
Echinococcus granulosus glutamate receptor 2 0.013 0.127 0.1306
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0119 0.0119
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0073 0.0602 0.0599
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0826 0.083
Chlamydia trachomatis glutamine binding protein 0.0058 0.042 0.1431
Loa Loa (eye worm) glutamate receptor 2 0.0179 0.1844 0.1896
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus glutamate receptor NMDA 0.0076 0.0632 0.065
Loa Loa (eye worm) TYRA-2 protein 0.0073 0.0602 0.0619
Echinococcus granulosus metabotropic glutamate receptor 2 0.0026 0.0048 0.0049
Plasmodium vivax V-type H(+)-translocating pyrophosphatase, putative 0.0265 0.2859 0.2925
Onchocerca volvulus Hexokinase homolog 0.0131 0.1282 0.5739
Echinococcus multilocularis neuropeptide s receptor 0.0073 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Plasmodium vivax PST-A protein 0.0135 0.1335 0.1355
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Giardia lamblia Farnesyl diphosphate synthase 0.0847 0.9725 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0521 0.0536
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0038 0.0192 0.0177
Brugia malayi SRC-1 0.0032 0.0119 0.0102
Brugia malayi aspartic protease BmAsp-2, identical 0.0042 0.0229 0.0215
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0073 0.0602 0.0599
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Schistosoma mansoni tyrosine kinase 0.0031 0.011 0.0092
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Brugia malayi Serotonin receptor 0.0073 0.0602 0.0599
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0073 0.0599 0.0616
Onchocerca volvulus 0.0114 0.1085 0.4825
Brugia malayi G-protein coupled receptor 0.0073 0.0602 0.0599
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0261 0.2812 0.2892
Echinococcus multilocularis tyrosine protein kinase shark 0.0136 0.1345 0.1345
Plasmodium falciparum glycogen synthase kinase 3 0.0057 0.0409 0.04
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.005 0.002
Echinococcus multilocularis serotonin receptor 0.0073 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0031 0.011 0.0113
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.0602 0.0599
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.0311
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0261 0.2812 1
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Brugia malayi hypothetical protein 0.0042 0.0229 0.0215
Onchocerca volvulus 0.008 0.0681 0.2946
Loa Loa (eye worm) AGC/PKA protein kinase 0.0025 0.0031 0.0031
Echinococcus granulosus g protein coupled receptor 0.0073 0.0602 0.0619
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0135 0.1335 0.1346
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Echinococcus multilocularis neuropeptide Y receptor 0.0073 0.0602 0.0602
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0104 0.0964 0.0991
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0038 0.0192 0.0192
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0026 0.005 0.0052
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0114 0.1085 0.1097
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0057 0.0409 0.04
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0073 0.0602 0.0619
Brugia malayi AKH receptor 0.0073 0.0602 0.0599
Leishmania major phosphatidylinositol 3-kinase, putative 0.0038 0.0192 0.0177
Treponema pallidum hexokinase (hxk) 0.0209 0.2198 0.4297
Brugia malayi LBP/BPI 0.0049 0.0313 0.0302
Onchocerca volvulus 0.0065 0.0511 0.2153
Schistosoma mansoni glutamate receptor NMDA 0.0281 0.3046 0.3118
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0261 0.2812 0.2877
Echinococcus multilocularis allatostatin A receptor 0.0073 0.0602 0.0602
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0057 0.0409 0.0409
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0026 0.005 0.002
Loa Loa (eye worm) hypothetical protein 0.0142 0.1416 0.1456
Plasmodium vivax glycogen synthase kinase 3, putative 0.0057 0.0409 0.04
Brugia malayi Angiotensin-converting enzyme family protein 0.0744 0.8505 0.8743
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0826 0.0849
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Echinococcus granulosus tyrosine protein kinase Fyn 0.0032 0.0119 0.0123
Loa Loa (eye worm) polyprenyl synthetase 0.0847 0.9725 1
Plasmodium vivax polyprenol reductase, putative 0.0049 0.0322 0.0311
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0261 0.2812 1
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0262 0.2833 0.2898
Plasmodium falciparum plasmepsin X 0.0042 0.0229 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0313 0.0292
Loa Loa (eye worm) hypothetical protein 0.0065 0.0511 0.0525
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0236 0.2524 0.2572
Plasmodium vivax plasmepsin V, putative 0.0042 0.0229 0.0215
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0065 0.0511 0.0505
Plasmodium falciparum plasmepsin VIII, putative 0.0042 0.0229 0.0215
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0075 0.0629 0.0627
Mycobacterium tuberculosis Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (biotin--protein ligas 0.0027 0.0056 0.0037
Loa Loa (eye worm) G-protein coupled receptor 0.0073 0.0602 0.0619
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0025 0.0031 0.0011
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0073 0.0602 0.2577
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0132 0.1299 0.1336
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0057 0.0409 0.042
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0038 0.0192 0.0177
Leishmania major monoglyceride lipase, putative 0.0135 0.1335 0.1355
Schistosoma mansoni amine GPCR 0.0073 0.0602 0.0599
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0847 0.9725 1
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.0602 0.0619
Schistosoma mansoni histamine h1 receptor 0.0073 0.0602 0.0599
Brugia malayi Pyridoxal-dependent decarboxylase conserved domain containing protein 0.0074 0.0615 0.0613
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0228 0.2421 0.8609
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus multilocularis G-protein coupled receptor, putative 0.0073 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0032 0.0119 0.0119
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0073 0.0602 0.0602
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0049 0.0322 0.03
Trypanosoma cruzi cdc2-related kinase 3 0.0026 0.005 0.0031
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0065 0.0511 0.0505
Brugia malayi ORL1-like opioid receptor 0.0073 0.0602 0.0599
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0073 0.0602 0.0619
Leishmania major hexokinase, putative 0.0209 0.2198 0.2244
Schistosoma mansoni biotin-protein ligase 0.0052 0.0348 0.0338
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0261 0.2812 0.2877
Echinococcus granulosus fmrfamide receptor 0.0073 0.0602 0.0619
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0133 0.1303 0.1303
Echinococcus multilocularis purine nucleoside phosphorylase 0.0092 0.0824 0.0824
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0101 0.0933 0.096
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0038 0.0192 0.0197
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0198 0.2072 0.2072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0073 0.0602 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0402 0.0383
Schistosoma mansoni cathepsin D (A01 family) 0.0518 0.5847 0.6004
Echinococcus multilocularis biotin protein ligase 0.0038 0.0186 0.0186
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0348 0.1239
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0261 0.2812 0.2877
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0602 0.0602
Trypanosoma cruzi polyprenyl synthase, putative 0.0454 0.509 0.5223
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0826 0.083
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0073 0.0602 0.0602
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0135 0.1335 0.4748
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0026 0.0048 0.0048
Brugia malayi hypothetical protein 0.0026 0.0048 0.0028
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0847 0.9725 1
Trypanosoma brucei monoglyceride lipase, putative 0.0135 0.1335 0.1355
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.0311
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0042 0.0229 0.0204
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0032 0.0119 0.0119
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.0602 0.0599
Brugia malayi Pepsin A precursor 0.0042 0.0229 0.0215
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0073 0.0602 0.0599
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0067 0.0526 0.0521
Echinococcus multilocularis glutamate receptor NMDA 0.0076 0.0632 0.0632
Echinococcus granulosus neuropeptide FF receptor 2 0.0073 0.0602 0.0619
Toxoplasma gondii aspartyl protease ASP1 0.0176 0.1811 0.1836
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0409 0.042
Entamoeba histolytica s phingosine-1-phosphate lyase 1, putative 0.0074 0.0615 0.2187
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0073 0.0602 0.0599
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0049 0.0322 0.03
Loa Loa (eye worm) hypothetical protein 0.0066 0.0521 0.0536
Schistosoma mansoni glutathione synthetase 0.0261 0.2812 0.2877
Echinococcus granulosus g-protein coupled receptor 0.0073 0.0602 0.0619
Schistosoma mansoni hypothetical protein 0.0073 0.0602 0.0599
Loa Loa (eye worm) hypothetical protein 0.0049 0.0313 0.0322
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus granulosus g protein coupled receptor 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.0229 0.0215
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.0602 0.0619
Echinococcus multilocularis purine nucleoside phosphorylase 0.0073 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0049
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0198 0.2072 0.2072
Echinococcus multilocularis orexin receptor type 2 0.0073 0.0602 0.0602
Trypanosoma cruzi extracellular receptor, putative 0.0026 0.0048 0.0028
Echinococcus multilocularis purine nucleoside phosphorylase 0.0092 0.0824 0.0824
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0847 0.9725 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.003 0.0094 0.0094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Echinococcus multilocularis neuropeptide Y receptor 0.0073 0.0602 0.0602
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0057 0.0409 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0322 0.03
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0024 0.002 0.002
Loa Loa (eye worm) hexokinase 0.0209 0.2198 0.2261
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0176 0.1811 0.1845
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0038 0.0192 0.0166
Mycobacterium ulcerans lysophospholipase 0.0135 0.1335 0.1355
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0205 0.2152 0.2213
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Brugia malayi hypothetical protein 0.0065 0.0511 0.0505
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0847 0.9725 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0299 0.3265 0.3357
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0038 0.0192 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Echinococcus granulosus 7TM GPCR rhodopsin 0.0073 0.0602 0.0619
Trypanosoma cruzi cdc2-related kinase 3 0.0026 0.005 0.0031
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0049 0.0322 0.03
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0602 0.0599
Brugia malayi metabotropic glutamate receptor type 2 0.0026 0.0048 0.0028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0073 0.0602 0.0599
Echinococcus granulosus G protein coupled receptor 139 0.0073 0.0602 0.0619
Echinococcus multilocularis neuropeptide receptor 0.0073 0.0602 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0031 0.0011
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0049 0.0322 0.0331
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.0602 0.0602
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Echinococcus granulosus neuropeptide receptor 0.0073 0.0602 0.0619
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0847 0.9725 1
Schistosoma mansoni cathepsin D (A01 family) 0.0518 0.5847 0.6004
Schistosoma mansoni biogenic amine receptor 0.0073 0.0602 0.0599
Echinococcus multilocularis receptor type guanylyl cyclase 0.0031 0.011 0.011
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0024 0.002 0.002
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0261 0.2812 1
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0847 0.9725 1
Schistosoma mansoni neuropeptide receptor 0.0073 0.0602 0.0599
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0454 0.509 0.5223
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus multilocularis glutamate receptor 2 0.0179 0.1844 0.1844
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0073 0.0602 0.0599
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0057 0.0409 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0751 0.0753
Loa Loa (eye worm) hypothetical protein 0.0049 0.0322 0.0331
Schistosoma mansoni tyrosine kinase 0.0031 0.011 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0031 0.0011
Treponema pallidum octaprenyl-diphosphate synthase 0.0454 0.509 1
Brugia malayi putative neuropeptide receptor 0.0073 0.0602 0.0599
Echinococcus granulosus purine nucleoside phosphorylase 0.0092 0.0824 0.0847
Onchocerca volvulus 0.0049 0.0313 0.1236
Brugia malayi aspartic protease BmAsp-1, identical 0.0042 0.0229 0.0215
Schistosoma mansoni ATP-binding cassette transporter 0.0179 0.1844 0.1879
Loa Loa (eye worm) polyprenyl synthetase 0.0261 0.2812 0.2892
Trypanosoma brucei polo-like protein kinase 0.0056 0.0402 0.0393
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0038 0.0192 0.0177
Giardia lamblia Synaptic glycoprotein SC2 0.0049 0.0322 0.03
Onchocerca volvulus 0.0073 0.0602 0.2577
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0025 0.0031 0.0011
Onchocerca volvulus 0.0073 0.0602 0.2577
Echinococcus granulosus neuropeptide receptor A26 0.0073 0.0602 0.0619
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0261 0.2812 0.2892
Schistosoma mansoni amine GPCR 0.0073 0.0602 0.0599
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0263 0.2845 0.2925
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0073 0.0602 0.0599
Toxoplasma gondii hexokinase 0.0209 0.2198 0.2236
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.03
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0038 0.0192 0.0177
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0176 0.1811 0.1862
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0744 0.8505 0.8746
Loa Loa (eye worm) hypothetical protein 0.0065 0.0511 0.0525
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.0602 0.0602
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0065 0.0511 0.0505
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0049 0.0322 0.0311
Loa Loa (eye worm) AGC/PKA protein kinase 0.0025 0.0031 0.0031
Echinococcus granulosus tyrosine protein kinase Fyn 0.0032 0.0119 0.0123
Brugia malayi hypothetical protein 0.0073 0.0602 0.0599
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Echinococcus granulosus tachykinin peptides receptor 99D 0.0073 0.0602 0.0619
Brugia malayi serine/threonine-protein kinase plk-2 0.0056 0.0402 0.0393
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0229 0.0215
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0847 0.9725 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0073 0.0602 0.0599
Loa Loa (eye worm) amidase 0.0024 0.002 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0119 0.0119
Schistosoma mansoni purine nucleoside phosphorylase 0.0092 0.0824 0.0828
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0135 0.1329 0.1329
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0135 0.1335 0.1346
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0058 0.042 0.0412
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0056 0.0402 0.0413
Brugia malayi hypothetical protein 0.0065 0.0511 0.0505
Leishmania major farnesyl pyrophosphate synthase 0.0847 0.9725 1
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0042 0.0229 0.0235
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.005 0.002
Brugia malayi Glutamate receptor 1 precursor 0.0179 0.1844 0.1879
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0025 0.0031 0.0031
Trypanosoma brucei monoglyceride lipase, putative 0.0135 0.1335 0.1355
Echinococcus granulosus neuropeptide receptor 0.0073 0.0602 0.0619
Leishmania major hexokinase, putative 0.0209 0.2198 0.2244
Schistosoma mansoni memapsin-2 (A01 family) 0.0042 0.0229 0.0215
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0135 0.1335 0.1346
Brugia malayi Guanylyl cyclase protein 23 0.0031 0.011 0.0092
Brugia malayi Metabotropic glutamate receptor precursor. 0.0026 0.0048 0.0028
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0049 0.0322 0.0322
Onchocerca volvulus 0.0073 0.0602 0.2577
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0038 0.0192 0.0177
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0056 0.0402 0.0393
Loa Loa (eye worm) hypothetical protein 0.0042 0.0229 0.0235
Schistosoma mansoni neuropeptide receptor 0.0073 0.0602 0.0599
Schistosoma mansoni opsin-like receptor 0.0073 0.0602 0.0599
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0261 0.2812 0.2869
Schistosoma mansoni hypothetical protein 0.0073 0.0602 0.0599
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0073 0.0602 0.0619
Loa Loa (eye worm) hypothetical protein 0.0073 0.0602 0.0619
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0826 0.083
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0454 0.509 0.5223
Plasmodium falciparum V-type K+-independent H+-translocating inorganic pyrophosphatase 0.0265 0.2859 0.2925
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0058 0.042 0.0412

Activities

Activity type Activity value Assay description Source Reference
T1/2 (ADMET) = 2.6 min Half-life period of the compound was determined in 95% ethanol in dark at 28 degrees celsius. ChEMBL. 6694168

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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