Detailed information for compound 106656

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 538.597 | Formula: C23H38N8O7
  • H donors: 7 H acceptors: 7 LogP: -2.46 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 3
  • SMILES: NC(=NCCC[C@@H]1C(=O)NCC(=O)N[C@H](CC(=O)O)C(=O)NC/C=C\CC(=O)N[C@@H](C(=O)N1C)C(C)C)N
  • InChi: 1S/C23H38N8O7/c1-13(2)19-22(38)31(3)15(7-6-10-27-23(24)25)21(37)28-12-17(33)29-14(11-18(34)35)20(36)26-9-5-4-8-16(32)30-19/h4-5,13-15,19H,6-12H2,1-3H3,(H,26,36)(H,28,37)(H,29,33)(H,30,32)(H,34,35)(H4,24,25,27)/b5-4-/t14-,15-,19-/m1/s1
  • InChiKey: JJJYFRMPJYJNIF-MVOMDFKXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni integrin alpha Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus granulosus integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin alpha pat-2 Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum IPR013513,Integrin alpha chain, C-terminal cytoplasmic region,domain-containing Get druggable targets OG5_129341 All targets in OG5_129341
Brugia malayi Integrin alpha pat-2 precursor Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06476 integrin alpha 2B, putative Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus multilocularis integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Leishmania major metacaspase, putative 0.0016 0.0005 0.0014
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0356 0.2155 1
Echinococcus granulosus ring and YY1 binding protein 0.0568 0.3496 0.3492
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0031 0.0101 0.0101
Schistosoma mansoni RNA binding protein 0.0568 0.3496 0.3492
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0104 0.0559 0.0554
Toxoplasma gondii ran binding protein 0.0568 0.3496 0.3496
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0029 0.0087 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0559 0.1587
Leishmania major DNA polymerase kappa, putative 0.0091 0.0477 0.1366
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Echinococcus granulosus neutral alpha glucosidase AB 0.0022 0.0042 0.0036
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0074 0.0373 0.1729
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.006 0.0281 0.0276
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0029 0.0087 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Echinococcus multilocularis lysosomal alpha glucosidase 0.0098 0.0523 0.0518
Entamoeba histolytica hypothetical protein 0.005 0.0222 0.2013
Trypanosoma brucei PAB1-binding protein , putative 0.0016 0.0007 0.0021
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1596 1 1
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Schistosoma mansoni hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.0885 0.088
Trypanosoma brucei DNA repair protein, putative 0.0029 0.0087 0.0249
Onchocerca volvulus 0.0568 0.3496 0.3492
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0035 0.0127 0.0122
Brugia malayi Calcitonin receptor-like protein seb-1 0.0069 0.0344 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0029 0.0087 0.0082
Toxoplasma gondii hypothetical protein 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) runx1 0.0041 0.0167 0.0162
Echinococcus multilocularis microtubule associated protein 2 0.1376 0.8608 0.8607
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0029 0.0087 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0086 0.045 0.0446
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0265 0.026
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0048 0.021 0.0205
Brugia malayi Zinc finger protein 183 homolog 0.0029 0.0087 0.0082
Plasmodium vivax trophozoite exported protein 1, putative 0.0029 0.0087 0.0087
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0054 0.0243 0.0238
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.005 0.0222 0.0217
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Brugia malayi hypothetical protein 0.0037 0.0141 0.0136
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0059 0.0279 0.0797
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0022 0.0043 0.0038
Plasmodium vivax ataxin-2 like protein, putative 0.0016 0.0007 0.0007
Brugia malayi Pip kinase protein 2 0.0105 0.0569 0.0565
Giardia lamblia Zinc finger domain 0.0029 0.0087 0.0634
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0265 0.026
Schistosoma mansoni integrin alpha-ps 0.0043 0.0177 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0029 0.0087 0.0082
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0265 0.026
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0029 0.0087 0.0082
Mycobacterium ulcerans hypothetical protein 0.0222 0.1307 0.6064
Leishmania major hypothetical protein, conserved 0.0568 0.3496 1
Echinococcus multilocularis Protein lozenge 0.0041 0.0167 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Schistosoma mansoni hypothetical protein 0.0022 0.0043 0.0038
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0568 0.3496 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0059 0.0279 0.0784
Schistosoma mansoni alpha glucosidase 0.0022 0.0042 0.0036
Echinococcus granulosus dna polymerase eta 0.0137 0.0772 0.0767
Loa Loa (eye worm) hypothetical protein 0.0137 0.0772 0.0767
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0074 0.0373 0.0368
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0074 0.0373 0.0368
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0105 0.0569 0.0565
Plasmodium vivax multidomain scavenger receptor, putative 0.0037 0.0141 0.0141
Echinococcus granulosus RING finger protein 185 0.0029 0.0087 0.0082
Loa Loa (eye worm) CXXC zinc finger family protein 0.0036 0.0131 0.0126
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0122 0.0673 0.0669
Schistosoma mansoni caspase-3 (C14 family) 0.006 0.0281 0.0276
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0035 0.0127 0.0122
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0568 0.3496 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Schistosoma mansoni alpha-glucosidase 0.0084 0.0437 0.0432
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0029 0.0087 0.0087
Toxoplasma gondii hypothetical protein 0.0029 0.0087 0.0087
Brugia malayi CXXC zinc finger family protein 0.0036 0.0131 0.0126
Schistosoma mansoni cpg binding protein 0.0036 0.0131 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.021 0.0205
Brugia malayi latrophilin 2 splice variant baaae 0.0047 0.0205 0.02
Echinococcus multilocularis histone acetyltransferase MYST2 0.0035 0.0127 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Loa Loa (eye worm) glutathione reductase 0.0024 0.0059 0.0054
Brugia malayi Glycosyl hydrolases family 31 protein 0.0098 0.0523 0.0518
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0016 0.0005 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0222 0.1307 0.6064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.021 0.0587
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0559 0.1587
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0048 0.021 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Brugia malayi hypothetical protein 0.0016 0.0007 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0056 0.0257 0.1194
Schistosoma mansoni hypothetical protein 0.1596 1 1
Schistosoma mansoni DNA helicase recq1 0.0018 0.0019 0.0013
Brugia malayi ThiF family protein 0.0021 0.0034 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0074 0.0211
Mycobacterium ulcerans DNA polymerase IV 0.0104 0.0559 0.2595
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0019 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0054 0.0245 0.024
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0326 0.0321
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0031 0.0102 0.0102
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0029 0.0087 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.0037 0.0141 0.0136
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Brugia malayi Glycosyl hydrolases family 31 protein 0.0022 0.0042 0.0036
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Trypanosoma brucei trypanothione reductase 0.0024 0.0059 0.0169
Loa Loa (eye worm) hypothetical protein 0.0105 0.0569 0.0565
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0015 0 0.5
Schistosoma mansoni hypothetical protein 0.0022 0.0043 0.0038
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0029 0.0087 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0568 0.3496 1
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0042 0.0105
Onchocerca volvulus RING finger protein 141 homolog 0.0029 0.0087 0.0082
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus granulosus integrin alpha ps 0.004 0.0155 0.015
Schistosoma mansoni hypothetical protein 0.0054 0.0243 0.0238
Plasmodium falciparum LCCL domain-containing protein 0.0037 0.0141 0.0141
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0002
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0105 0.0569 0.0565
Echinococcus granulosus ring finger protein 113a 0.0029 0.0087 0.0082
Chlamydia trachomatis DNA topoisomerase I 0.1596 1 1
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0031 0.0102 0.0097
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Onchocerca volvulus 0.0568 0.3496 0.3492
Giardia lamblia DNA damage repair protein 0.0027 0.0074 0.0511
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Loa Loa (eye worm) pip kinase 2 0.0105 0.0569 0.0565
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0016 0.0005 0.0005
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Onchocerca volvulus 0.0568 0.3496 0.3492
Plasmodium vivax RING zinc finger protein, putative 0.0029 0.0087 0.0087
Trichomonas vaginalis DNA polymerase eta, putative 0.0104 0.0559 0.0554
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0559 0.1587
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1596 1 1
Brugia malayi hypothetical protein 0.0331 0.1997 0.1993
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Onchocerca volvulus 0.0029 0.0087 0.0082
Loa Loa (eye worm) integrin alpha pat-2 0.0285 0.1705 0.1701
Echinococcus granulosus Zinc finger RanBP2 type 0.0568 0.3496 0.3492
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0019 0.0019
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.006 0.0281 0.0276
Echinococcus multilocularis GPCR, family 2 0.0022 0.0043 0.0038
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0018 0.0016 0.0031
Plasmodium vivax DNA repair protein REV1, putative 0.0027 0.0074 0.0074
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0086 0.045 0.0446
Toxoplasma gondii RING zinc finger protein 0.0029 0.0087 0.0087
Trypanosoma cruzi DNA polymerase eta, putative 0.0137 0.0772 0.2196
Loa Loa (eye worm) mbt repeat family protein 0.0031 0.0099 0.0094
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Echinococcus multilocularis zinc finger protein Ran binding 0.0568 0.3496 0.3492
Loa Loa (eye worm) hypothetical protein 0.0031 0.0102 0.0097
Onchocerca volvulus 0.0054 0.0245 0.024
Onchocerca volvulus 0.0029 0.0087 0.0082
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0029 0.0087 0.0082
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Brugia malayi RING zinc finger protein 0.0029 0.0087 0.0082
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0029 0.0087 0.0235
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0181 0.0176
Loa Loa (eye worm) hypothetical protein 0.0568 0.3496 0.3492
Trypanosoma brucei unspecified product 0.0099 0.0532 0.1522
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0054 0.0243 0.0238
Echinococcus multilocularis dna polymerase kappa 0.0104 0.0559 0.0554
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0029 0.0087 0.0082
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0385 0.038
Onchocerca volvulus 0.0031 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0331 0.1997 0.1993
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Echinococcus granulosus ring finger protein 170 0.0029 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.004 0.0155 0.015
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0074 0.0373 0.0368
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0022 0.0043 0.0038
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.021 0.0601
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0136
Brugia malayi hypothetical protein 0.0029 0.0087 0.0082
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0568 0.3496 0.3492
Brugia malayi B-box zinc finger family protein 0.0029 0.0087 0.0082
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0031 0.0102 0.0097
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0029 0.0087 0.0082
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0074 0.0211
Echinococcus granulosus histone acetyltransferase MYST2 0.0035 0.0127 0.0122
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Chlamydia trachomatis SWIB complex protein 0.1596 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Loa Loa (eye worm) doublecortin family protein 0.0037 0.0141 0.0136
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0021 0.0034 0.0029
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0054 0.0243 0.0238
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0265 0.026
Loa Loa (eye worm) hypothetical protein 0.0162 0.0927 0.0922
Loa Loa (eye worm) thioredoxin reductase 0.0024 0.0059 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.0007 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0042 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0013
Schistosoma mansoni hypothetical protein 0.0029 0.0087 0.0082
Schistosoma mansoni hypothetical protein 0.0568 0.3496 0.3492
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Schistosoma mansoni loxhd1 0.0037 0.0141 0.0136
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.0532 0.1522
Brugia malayi hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.0568 0.3496 1
Onchocerca volvulus Protein neuralized homolog 0.0029 0.0087 0.0082
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1596 1 1
Loa Loa (eye worm) brahma associated protein 0.1596 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0089 0.0089
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0022 0.0042 0.0042
Brugia malayi YY1-associated factor 2 0.0568 0.3496 0.3492
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0022 0.0042 0.0036
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0074 0.0373 0.0368
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0031 0.0102 0.0097
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0086 0.045 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Echinococcus multilocularis dna polymerase eta 0.0137 0.0772 0.0767
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0136
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0021 0.0034 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0074 0.0373 0.1729
Onchocerca volvulus 0.0568 0.3496 0.3492
Echinococcus granulosus cpg binding protein 0.0038 0.0144 0.0139
Schistosoma mansoni caspase-7 (C14 family) 0.006 0.0281 0.0276
Leishmania major mitochondrial DNA polymerase beta 0.0421 0.2567 0.7344
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0092 0.0489 0.2267
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0199 0.1165 0.3331
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0029 0.0087 0.0082
Giardia lamblia Ser/Thr protein kinase 0.0029 0.0087 0.0634
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1596 1 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0048 0.021 0.1771
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0568 0.3496 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0265 0.026
Echinococcus multilocularis integrin alpha ps 0.0083 0.0428 0.0423
Entamoeba histolytica hypothetical protein 0.005 0.0222 0.2013
Echinococcus granulosus lysosomal alpha glucosidase 0.0098 0.0523 0.0518
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0029 0.0087 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.0885 0.088
Mycobacterium ulcerans aldehyde dehydrogenase 0.0039 0.0153 0.0709
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma brucei glucosidase, putative 0.0022 0.0042 0.0119
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0091 0.0477 0.1366
Echinococcus granulosus RUN 0.0037 0.0141 0.0136
Entamoeba histolytica hypothetical protein 0.0029 0.0087 0.0791
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Toxoplasma gondii hypothetical protein 0.0068 0.0334 0.0334
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0042 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0104 0.0559 0.16
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trichomonas vaginalis ankyrin, putative 0.0029 0.0087 0.0082
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Schistosoma mansoni integrin alpha-ps 0.0083 0.0428 0.0423
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0022 0.0042 0.0378
Brugia malayi Doublecortin family protein 0.0037 0.0141 0.0136
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0052 0.0149
Loa Loa (eye worm) hypothetical protein 0.0331 0.1997 0.1993
Brugia malayi Thioredoxin reductase 0.0024 0.0059 0.0054
Trichomonas vaginalis hypothetical protein 0.0029 0.0087 0.0082
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0031 0.0099 0.0094
Echinococcus multilocularis L aminoadipate semialdehyde 0.0054 0.0245 0.024
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0019 0.0019
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0021 0.0034 0.0029
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0199 0.1165 0.3331
Trypanosoma brucei chrX additional, unordered contigs 0.0027 0.0074 0.0211
Schistosoma mansoni DNA polymerase eta 0.0137 0.0772 0.0767
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0057 0.0265 0.026
Entamoeba histolytica deoxycytidyl transferase, putative 0.0086 0.045 0.4093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0568 0.3496 1
Giardia lamblia Kinase, NEK 0.0029 0.0087 0.0634
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0031 0.0099 0.0094
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0021 0.0034 0.0034
Trypanosoma brucei predicted zinc finger protein 0.0029 0.0087 0.0249
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0056 0.0257 0.1194
Toxoplasma gondii LsmAD domain-containing protein 0.0016 0.0007 0.0007
Plasmodium vivax thioredoxin reductase, putative 0.0024 0.0059 0.0059
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0356 0.2155 0.2155
Onchocerca volvulus 0.0057 0.0262 0.0257
Echinococcus multilocularis RUN 0.0037 0.0141 0.0136
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Toxoplasma gondii hypothetical protein 0.0029 0.0087 0.0087
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Schistosoma mansoni peter pan-related 0.0029 0.0087 0.0082
Schistosoma mansoni aldehyde dehydrogenase 0.0039 0.0153 0.0148
Schistosoma mansoni TRABID protein (C64 family) 0.0568 0.3496 0.3492
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0059 0.0279 0.0784
Echinococcus multilocularis SAM and MBT domain containing protein 0.0031 0.0099 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0582 0.0577
Schistosoma mansoni hypothetical protein 0.1596 1 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0025 0.0061 0.0056
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1596 1 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0024 0.0059 0.0274
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0029 0.0087 0.0087
Leishmania major DNA polymerase eta, putative 0.0137 0.0772 0.2207
Echinococcus multilocularis ring finger protein 113a 0.0029 0.0087 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0074 0.0211
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0062 0.0297 0.1377
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Brugia malayi Probable ATP-dependent helicase DHX35 0.0121 0.0672 0.0667
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0048 0.021 0.0205
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Brugia malayi hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0029 0.0087 0.0082
Trypanosoma brucei ring finger containing protein 0.0029 0.0087 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Entamoeba histolytica hypothetical protein 0.005 0.0222 0.2013
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0183 0.0522
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0022 0.0043 0.0038
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0072 0.0361 0.1019
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0105 0.0569 0.0565
Schistosoma mansoni cpg binding protein 0.0038 0.0144 0.0139
Loa Loa (eye worm) hypothetical protein 0.014 0.0788 0.0783
Schistosoma mansoni hypothetical protein 0.0022 0.0043 0.0038
Brugia malayi brahma associated protein 60 kDa 0.1596 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0183 0.0178
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0029 0.0087 0.0082
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0123 0.0118
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0042 0.0036
Mycobacterium tuberculosis Probable reductase 0.0056 0.0257 0.1194
Trichomonas vaginalis sucrase-isomaltase, putative 0.0022 0.0042 0.0036
Schistosoma mansoni rnf5 0.0029 0.0087 0.0082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0039 0.0153 0.0709
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Onchocerca volvulus 0.1596 1 1
Loa Loa (eye worm) ThiF family protein 0.0021 0.0034 0.0029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0062 0.0297 0.1377
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.0885 0.088
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0029 0.0087 0.0249
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Plasmodium vivax metacaspase 1, putative 0.0016 0.0005 0.0005
Giardia lamblia Kinase, NEK 0.0029 0.0087 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.0885 0.088
Brugia malayi hypothetical protein 0.005 0.0222 0.0217
Leishmania major hypothetical protein, conserved 0.0568 0.3496 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0086 0.045 0.0446
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0059 0.0279 0.0784
Loa Loa (eye worm) hypothetical protein 0.0031 0.0099 0.0094
Leishmania major hypothetical protein, conserved 0.0568 0.3496 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0022 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.0568 0.3496 0.3492
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0421 0.2567 0.7344
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0029 0.0087 0.0634
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Brugia malayi Integrin alpha cytoplasmic region family protein 0.014 0.0788 0.0783
Schistosoma mansoni zinc finger protein 0.0029 0.0087 0.0082
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0568 0.3496 0.3492
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0054 0.0243 0.0238
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0421 0.2567 0.734
Echinococcus granulosus zinc finger protein Ran binding 0.0568 0.3496 0.3492
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0074 0.0197
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0181 0.0176
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0029 0.0087 0.0082
Toxoplasma gondii helicase, putative 0.0029 0.0087 0.0087
Echinococcus granulosus bloom syndrome protein 0.0044 0.0181 0.0176
Echinococcus multilocularis integrin alpha ps 0.0083 0.0428 0.0423
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0048 0.021 0.0205
Plasmodium falciparum RING zinc finger protein, putative 0.0029 0.0087 0.0087
Brugia malayi hypothetical protein 0.0029 0.0087 0.0082
Mycobacterium ulcerans DNA polymerase IV 0.0104 0.0559 0.2595
Brugia malayi SWIB/MDM2 domain containing protein 0.1596 1 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trypanosoma cruzi hypothetical protein 0.0029 0.0087 0.0235
Trichomonas vaginalis ankyrin, putative 0.0029 0.0087 0.0082
Echinococcus multilocularis SWI:SNF matrix associated 0.1596 1 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0568 0.3496 0.3492
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0074 0.0211
Toxoplasma gondii thioredoxin reductase 0.0024 0.0059 0.0059
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0183 0.106 0.1056
Schistosoma mansoni apoptosis regulator bax 0.0054 0.0243 0.0238
Trypanosoma brucei metacaspase MCA2 0.0016 0.0005 0.0014
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0568 0.3496 0.3492
Schistosoma mansoni hypothetical protein 0.0188 0.1091 0.1086
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0029 0.0087 0.0087
Echinococcus multilocularis ubiquitin specific protease 41 0.0048 0.021 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0054 0.0245 0.024
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Mycobacterium tuberculosis Probable dehydrogenase 0.0056 0.0257 0.1194
Plasmodium falciparum glutathione reductase 0.0024 0.0059 0.0059
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0091 0.0091
Toxoplasma gondii hypothetical protein 0.0029 0.0087 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0568 0.3496 1
Plasmodium falciparum DNA repair protein REV1, putative 0.0027 0.0074 0.0074
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Schistosoma mansoni cellular tumor antigen P53 0.0201 0.1175 0.117
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.021 0.0205
Schistosoma mansoni polycystin 1-related 0.0037 0.0141 0.0136
Leishmania major hypothetical protein 0.0029 0.0087 0.0249
Leishmania major DNA damage repair protein, putative 0.0027 0.0074 0.0211
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1596 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0205
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0155 0.0885 0.088
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0074 0.0197
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0028 0.0083 0.0078
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Schistosoma mansoni lozenge 0.0041 0.0167 0.0162
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0183 0.0522
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0054 0.0243 0.0238
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Plasmodium falciparum trophozoite exported protein 1 0.0029 0.0087 0.0087
Mycobacterium tuberculosis Probable oxidoreductase 0.0062 0.0297 0.1377
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0356 0.2155 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Leishmania major ubiquitin-activating enzyme-like protein 0.0021 0.0034 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0092 0.0489 0.2267
Echinococcus granulosus SWI:SNF matrix associated 0.1596 1 1
Schistosoma mansoni lipoxygenase 0.0183 0.106 0.1056
Echinococcus granulosus GPCR family 2 0.0022 0.0043 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.0007 0.0007
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0183 0.106 0.1056
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0052 0.0135
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0189 0.11 1
Plasmodium falciparum zinc finger protein, putative 0.0029 0.0087 0.0087
Leishmania major hypothetical protein, conserved 0.0568 0.3496 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0074 0.0197
Schistosoma mansoni rab6-interacting 0.0037 0.0141 0.0136
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Echinococcus multilocularis SWI:SNF matrix associated 0.1596 1 1
Schistosoma mansoni cpg binding protein 0.0038 0.0144 0.0139
Schistosoma mansoni hypothetical protein 0.0022 0.0043 0.0038
Leishmania major DNA polymerase kappa, putative 0.0027 0.0074 0.0211
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0074 0.0373 0.1729
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0105 0.0569 0.0565
Plasmodium vivax DNA repair protein RAD5, putative 0.0029 0.0087 0.0087
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0568 0.3496 1
Trypanosoma cruzi hypothetical protein, conserved 0.0568 0.3496 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0016 0.0005 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0568 0.3496 1
Giardia lamblia Kinase 0.0029 0.0087 0.0634
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0029 0.0087 0.0082
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0042 0.0036
Trypanosoma cruzi hypothetical protein 0.0029 0.0087 0.0235
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1596 1 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Echinococcus granulosus dnaJ subfamily B 0.051 0.313 0.3127
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0568 0.3496 0.3492
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0105 0.0569 0.0565
Mycobacterium tuberculosis Conserved hypothetical protein 0.0086 0.045 0.209
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0022 0.0042 0.0036
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0029 0.0087 0.0082
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1596 1 1
Trichomonas vaginalis conserved hypothetical protein 0.1596 1 1
Trypanosoma brucei metacaspase 5, putative 0.0016 0.0005 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0559 0.1587
Echinococcus multilocularis RING finger protein 185 0.0029 0.0087 0.0082
Onchocerca volvulus 0.0037 0.0141 0.0136
Schistosoma mansoni rab6-interacting 0.0037 0.0141 0.0136
Giardia lamblia Fructose-bisphosphate aldolase 0.0189 0.11 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0568 0.3496 0.3496
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0582 0.0577
Echinococcus multilocularis integrin alpha 3 0.0142 0.08 0.0795
Trypanosoma brucei unspecified product 0.006 0.0281 0.0804
Schistosoma mansoni hypothetical protein 0.0037 0.0141 0.0136
Schistosoma mansoni lipoxygenase 0.0116 0.0635 0.0631
Schistosoma mansoni hypothetical protein 0.0054 0.0243 0.0238
Echinococcus multilocularis SWI:SNF matrix associated 0.1596 1 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.021 0.0587
Onchocerca volvulus Putative RING finger protein 207 0.0029 0.0087 0.0082
Echinococcus granulosus microtubule associated protein 2 0.1376 0.8608 0.8607
Echinococcus granulosus Polycystic kidney disease protein 0.0037 0.0141 0.0136
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Entamoeba histolytica hypothetical protein 0.005 0.0222 0.2013
Schistosoma mansoni DNA helicase recq5 0.0018 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0102 0.0549 0.0544
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Echinococcus granulosus integrin alpha ps 0.0083 0.0428 0.0423
Schistosoma mansoni aldehyde dehydrogenase 0.0039 0.0153 0.0148
Onchocerca volvulus Glucosylceramidase homolog 0.0102 0.0547 0.0543
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0029 0.0087 0.0082
Schistosoma mansoni DNA polymerase IV / kappa 0.0027 0.0074 0.0069
Loa Loa (eye worm) hypothetical protein 0.0121 0.0672 0.0667
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Toxoplasma gondii ThiF family protein 0.0021 0.0034 0.0034
Echinococcus multilocularis ring and YY1 binding protein 0.0568 0.3496 0.3492
Loa Loa (eye worm) MBCTL1 0.0035 0.0127 0.0122
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Echinococcus multilocularis integrin alpha ps 0.004 0.0155 0.015
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0308 0.0881
Echinococcus multilocularis lipoxygenase domain containing protein 0.0037 0.0141 0.0136
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0122 0.0673 0.0669
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0039 0.0153 0.0437
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Echinococcus multilocularis caspase 0.006 0.0281 0.0276
Plasmodium falciparum metacaspase 1 0.0016 0.0005 0.0005
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0059 0.0155
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0568 0.3496 0.3496
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0189 0.11 1
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0052 0.0047
Onchocerca volvulus 0.0037 0.0141 0.0136
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0074 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Brugia malayi Neuralized family protein 0.0029 0.0087 0.0082
Plasmodium falciparum thioredoxin reductase 0.0024 0.0059 0.0059
Mycobacterium ulcerans hypothetical protein 0.0027 0.0074 0.0342
Echinococcus granulosus lipoxygenase domain containing protein 0.0037 0.0141 0.0136
Echinococcus granulosus dna polymerase kappa 0.0104 0.0559 0.0554
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Schistosoma mansoni alpha-glucosidase 0.0084 0.0437 0.0432
Brugia malayi Latrophilin receptor protein 2 0.0022 0.0043 0.0038
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0054 0.0243 0.0238
Plasmodium vivax ubiquitin activating enzyme, putative 0.0031 0.0102 0.0102
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0039 0.0153 0.0148
Echinococcus granulosus polycomb protein SCMH1 0.0031 0.0099 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0199 0.1165 0.3322
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0091 0.0477 0.1366
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0308 0.0881
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Trypanosoma cruzi WLM domain containing protein, putative 0.0568 0.3496 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0155 0.0885 0.088
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0086 0.045 0.0446
Leishmania major alpha glucosidase II subunit, putative 0.0022 0.0042 0.0119
Leishmania major trypanothione reductase 0.0024 0.0059 0.0169
Brugia malayi RING finger protein 20 0.0029 0.0087 0.0082
Schistosoma mansoni microtubule-associated protein tau 0.1376 0.8608 0.8607
Echinococcus granulosus caspase 0.006 0.0281 0.0276
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0181 0.0176
Schistosoma mansoni peter pan-related 0.0029 0.0087 0.0082
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0568 0.3496 0.3492
Onchocerca volvulus 0.0036 0.0131 0.0126
Plasmodium vivax glutathione reductase, putative 0.0024 0.0059 0.0059
Schistosoma mansoni zinc finger protein 0.0568 0.3496 0.3492
Leishmania major DNA polymerase eta, putative 0.0078 0.0395 0.113
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0029 0.0087 0.0082
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0029 0.0087 0.0087
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Echinococcus granulosus lipoxygenase domain containing protein 0.0037 0.0141 0.0136
Echinococcus granulosus cell growth regulator with ring finger domain 0.0029 0.0087 0.0082
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0019 0.0013
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0021 0.0034 0.0098
Entamoeba histolytica hypothetical protein 0.0029 0.0087 0.0791
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.021 0.0205
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0057 0.0265 0.026
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Leishmania major DNA repair protein-like protein 0.0029 0.0087 0.0249
Schistosoma mansoni sex comb on midleg homolog 0.0031 0.0099 0.0094
Plasmodium falciparum metacaspase-like protein 0.0016 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Schistosoma mansoni brg-1 associated factor 0.1596 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Toxoplasma gondii aldehyde dehydrogenase 0.0039 0.0153 0.0153
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0048 0.021 0.0205
Trypanosoma brucei unspecified product 0.006 0.0281 0.0804
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0062 0.0297 0.1377
Trypanosoma brucei metacaspase MCA3 0.0016 0.0005 0.0014
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Brugia malayi ThiF family protein 0.0031 0.0102 0.0097
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus multilocularis neutral alpha glucosidase AB 0.0022 0.0042 0.0036
Onchocerca volvulus 0.0029 0.0087 0.0082
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0074 0.0373 0.1066
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0029 0.0087 0.0082
Leishmania major hypothetical protein, conserved 0.0568 0.3496 1
Loa Loa (eye worm) hypothetical protein 0.0568 0.3496 0.3492
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0069 0.0344 0.0339
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0048 0.021 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0098 0.0523 0.0518
Onchocerca volvulus 0.0029 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0082
Giardia lamblia Zinc finger domain 0.0029 0.0087 0.0634
Schistosoma mansoni myelin transcription factor 1 myt1 0.0035 0.0127 0.0122
Brugia malayi hypothetical protein 0.0029 0.0087 0.0082
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0039 0.0153 0.0709
Brugia malayi mbt repeat family protein 0.0031 0.0099 0.0094
Leishmania major hypothetical protein, conserved 0.0016 0.0007 0.0021
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0029 0.0087 0.0082
Schistosoma mansoni terminal deoxycytidyl transferase 0.0086 0.045 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.0547 0.0543
Treponema pallidum fructose-bisphosphate aldolase 0.0189 0.11 0.5105
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0113 0.0618 0.0614
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0056 0.0257 0.1194
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0265 0.026
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0056 0.0257 0.1194
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0421 0.2567 0.734
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0356 0.2155 0.2155
Echinococcus multilocularis 0.0029 0.0087 0.0082
Schistosoma mansoni hypothetical protein 0.1596 1 1
Schistosoma mansoni hypothetical protein 0.005 0.0222 0.0217
Loa Loa (eye worm) DEAH box polypeptide 35 0.0121 0.0672 0.0667
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0019 0.0013
Echinococcus multilocularis ring finger protein 170 0.0029 0.0087 0.0082
Schistosoma mansoni transcription factor LCR-F1 0.005 0.0222 0.0217
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0568 0.3496 1
Echinococcus multilocularis dnaJ subfamily B 0.051 0.313 0.3127
Toxoplasma gondii hypothetical protein 0.0031 0.0102 0.0102
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.0007 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.0137 0.0772 0.0767
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0019 0.0013
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0559 0.16
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0022 0.0042 0.0036
Onchocerca volvulus 0.0113 0.0618 0.0614
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0029 0.0087 0.0235
Loa Loa (eye worm) hypothetical protein 0.0145 0.0821 0.0817
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0249
Onchocerca volvulus 0.0331 0.1997 0.1993
Trypanosoma cruzi DNA polymerase eta, putative 0.0078 0.0395 0.1117
Giardia lamblia DINP protein human, muc B family 0.0091 0.0477 0.4242
Echinococcus multilocularis tumor protein p63 0.1372 0.8585 0.8585
Entamoeba histolytica zinc finger domain containing protein 0.0029 0.0087 0.0791
Schistosoma mansoni fusion 0.0568 0.3496 0.3492
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0042 0.0105
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0029 0.0087 0.0249
Onchocerca volvulus 0.0029 0.0087 0.0082
Echinococcus multilocularis thioredoxin glutathione reductase 0.0025 0.0061 0.0056
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0122
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0042 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0104 0.0559 0.16
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0568 0.3496 0.3492
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0021 0.0034 0.0083
Brugia malayi Integrin alpha pat-2 precursor 0.0185 0.1073 0.1068
Echinococcus granulosus tumor protein p63 0.1372 0.8585 0.8585
Echinococcus multilocularis lysosomal alpha glucosidase 0.0098 0.0523 0.0518
Echinococcus multilocularis caspase 3 0.0044 0.018 0.0175
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Onchocerca volvulus 0.0029 0.0087 0.0082
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0092 0.0489 0.2267
Loa Loa (eye worm) hypothetical protein 0.0568 0.3496 0.3492
Treponema pallidum hypothetical protein 0.0356 0.2155 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0189 0.11 0.1096
Brugia malayi polk-prov protein 0.0044 0.0183 0.0178
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0022 0.0042 0.0378
Echinococcus multilocularis cpg binding protein 0.0038 0.0144 0.0139
Entamoeba histolytica SPRY domain protein 0.0029 0.0087 0.0791
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0019 0.0013
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0019 0.0013
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0356 0.2155 1
Trypanosoma brucei Metacaspase-4 0.0016 0.0005 0.0014
Loa Loa (eye worm) RecQ helicase 0.0044 0.0181 0.0176
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0029 0.0087 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0029 0.0087 0.0087
Echinococcus granulosus SAM and MBT domain containing protein 0.0031 0.0099 0.0094
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0568 0.3496 0.3492
Loa Loa (eye worm) hypothetical protein 0.0043 0.0177 0.0172
Echinococcus granulosus integrin alpha 3 0.0142 0.08 0.0795
Brugia malayi mbt repeat family protein 0.0031 0.0099 0.0094
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0056 0.0257 0.1194
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0039 0.0153 0.0148
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0249
Loa Loa (eye worm) RING finger protein 20 0.0029 0.0087 0.0082
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0069 0.0344 0.0339
Loa Loa (eye worm) hypothetical protein 0.0568 0.3496 0.3492
Schistosoma mansoni ring finger protein 151 0.0029 0.0087 0.0082
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0035 0.0127 0.0122
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0333 0.0333
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0052 0.0474
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0054 0.0245 0.024
Echinococcus granulosus L aminoadipate semialdehyde 0.0054 0.0245 0.024
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0021 0.0034 0.0034
Brugia malayi hypothetical protein 0.0029 0.0087 0.0082
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0091 0.0477 0.2215
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0022 0.0043 0.0038
Schistosoma mansoni hypothetical protein 0.0054 0.0243 0.0238
Leishmania major hypothetical protein, unknown function 0.0029 0.0087 0.0249
Loa Loa (eye worm) apoptosis regulator protein 0.0054 0.0243 0.0238
Schistosoma mansoni hypothetical protein 0.0029 0.0087 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.0885 0.088
Brugia malayi hypothetical protein 0.0113 0.0618 0.0614
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0087 0.0235
Brugia malayi Zinc finger, C2H2 type family protein 0.0029 0.0087 0.0082
Echinococcus multilocularis Polycystic kidney disease protein 0.0037 0.0141 0.0136
Echinococcus granulosus caspase 3 0.0044 0.018 0.0175
Brugia malayi glutathione reductase 0.0024 0.0059 0.0054
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0181 0.0176
Trypanosoma cruzi WLM domain containing protein, putative 0.0568 0.3496 1
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Brugia malayi hypothetical protein 0.0037 0.0141 0.0136
Loa Loa (eye worm) latrophilin receptor protein 2 0.0022 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.0201 0.1175 0.117
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Schistosoma mansoni mind bomb 0.0029 0.0087 0.0082
Plasmodium vivax hypothetical protein, conserved 0.1596 1 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0147 0.0147
Giardia lamblia Hypothetical protein 0.0029 0.0087 0.0634
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0078 0.0395 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0308 0.0881
Trichomonas vaginalis ion channel nompc, putative 0.0029 0.0087 0.0082
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0048 0.021 0.191
Schistosoma mansoni sex comb on midleg homolog 0.0031 0.0099 0.0094
Plasmodium vivax zinc finger protein, putative 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0054 0.0243 0.0238
Schistosoma mansoni hypothetical protein 0.0047 0.0205 0.02
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0048 0.021 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0087 0.0082
Trypanosoma brucei DNA polymerase eta, putative 0.0137 0.0772 0.2207
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0568 0.3496 1
Schistosoma mansoni integrin alpha 0.0185 0.1073 0.1068
Echinococcus granulosus ubiquitin specific protease 41 0.0048 0.021 0.0205
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0052 0.0149
Trichomonas vaginalis ankyrin, putative 0.0029 0.0087 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.0885 0.088
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.005 0.0222 0.0217
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0048 0.021 0.0601
Trypanosoma brucei metacaspase 0.0016 0.0005 0.0014
Giardia lamblia Ribonuclease 0.0029 0.0087 0.0634
Schistosoma mansoni hypothetical protein 0.051 0.313 0.3127
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0029 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0047 0.0205 0.02
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0029 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.004 0.0155 0.015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0069 0.0344 0.0339
Echinococcus multilocularis polycomb protein SCMH1 0.0031 0.0099 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0087 0.0082
Onchocerca volvulus 0.0201 0.1175 0.117
Loa Loa (eye worm) RiNg Finger protein family member 0.0029 0.0087 0.0082
Giardia lamblia Protein 21.1 0.0029 0.0087 0.0634
Trichomonas vaginalis maltase-glucoamylase, putative 0.0022 0.0042 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0039 0.0153 0.0709
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0029 0.0087 0.0235
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0265 0.026

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.2 uM Inhibition of platelet aggregation using human platelet rich plasma (hPRP) assay (200microL, 2-3 x 10e 8 platelets/mL, n=1) ChEMBL. No reference
IC50 (functional) = 0.2 uM Inhibition of platelet aggregation using human platelet rich plasma (hPRP) assay (200microL, 2-3 x 10e 8 platelets/mL, n=1) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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